FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2409, 221 aa
  1>>>pF1KE2409 221 - 221 aa - 221 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.4156+/-0.000289; mu= 9.1940+/- 0.018
 mean_var=91.4710+/-18.401, 0's: 0 Z-trim(119.9): 7  B-trim: 0 in 0/54
 Lambda= 0.134101
 statistics sampled from 34568 (34575) to 34568 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.405), width:  16
 Scan time:  5.480

The best scores are:                                      opt bits E(85289)
NP_085048 (OMIM: 612050) NEDD4 family-interacting  ( 221) 1506 300.6 1.4e-81
XP_006719903 (OMIM: 610041) PREDICTED: NEDD4 famil ( 335)  822 168.3 1.3e-41
NP_061953 (OMIM: 610041) NEDD4 family-interacting  ( 336)  822 168.3 1.3e-41
NP_001154879 (OMIM: 610041) NEDD4 family-interacti ( 316)  410 88.6 1.2e-17


>>NP_085048 (OMIM: 612050) NEDD4 family-interacting prot  (221 aa)
 initn: 1506 init1: 1506 opt: 1506  Z-score: 1585.9  bits: 300.6 E(85289): 1.4e-81
Smith-Waterman score: 1506; 100.0% identity (100.0% similar) in 221 aa overlap (1-221:1-221)

               10        20        30        40        50        60
pF1KE2 MALALAALAAVEPACGSRYQQLQNEEESGEPEQAAGDAPPPYSSISAESAAYFDYKDESG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 MALALAALAAVEPACGSRYQQLQNEEESGEPEQAAGDAPPPYSSISAESAAYFDYKDESG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 FPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEDFVGRDDFDDADQLRIGNDGIFML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 FPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEDFVGRDDFDDADQLRIGNDGIFML
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 TFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 TFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWL
              130       140       150       160       170       180

              190       200       210       220 
pF1KE2 WWVFLVLGFLLFLRGFINYAKVRKMPETFSNLPRTRVLFIY
       :::::::::::::::::::::::::::::::::::::::::
NP_085 WWVFLVLGFLLFLRGFINYAKVRKMPETFSNLPRTRVLFIY
              190       200       210       220 

>>XP_006719903 (OMIM: 610041) PREDICTED: NEDD4 family-in  (335 aa)
 initn: 910 init1: 669 opt: 822  Z-score: 867.9  bits: 168.3 E(85289): 1.3e-41
Smith-Waterman score: 822; 56.6% identity (76.3% similar) in 219 aa overlap (9-220:117-334)

                                     10         20        30       
pF1KE2                       MALALAALAAVE-PACGSRYQQLQNEEESGEPEQAAGD
                                     .:.: :  ..   :.  .  :. :   . .
XP_006 KPDPEPGRMDHHQPGTGRYQLLNEEDNSESSAIEQPPTSNPAPQIV-QAASSAPALETDS
         90       100       110       120       130        140     

        40        50        60         70        80        90      
pF1KE2 APPPYSSISAESAAYFDYKDESGF-PKPPSYNVATTLPSYDEAERTKAEATIPLVPG---
       .:::::::..:  .  : .  . : : :: :.:::.::.:::::..:: :    .     
XP_006 SPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQ
         150       160       170       180       190       200     

             100       110       120       130       140       150 
pF1KE2 --RDEDFVGRDDFDDADQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAIS
         ..:.   ::::.::::::.::::::::.:::::.:::.:: ::::.:.. ::::::: 
XP_006 RIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAIC
         210       220       230       240       250       260     

             160       170       180       190       200       210 
pF1KE2 GFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPETFSN
       :::::::::::::::: :: :::.:::::::.:::::.:::.:::.:: :::.: :... 
XP_006 GFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAA
         270       280       290       300       310       320     

             220 
pF1KE2 LPRTRVLFIY
         ::: .:. 
XP_006 AHRTRYFFLL
         330     

>>NP_061953 (OMIM: 610041) NEDD4 family-interacting prot  (336 aa)
 initn: 922 init1: 669 opt: 822  Z-score: 867.9  bits: 168.3 E(85289): 1.3e-41
Smith-Waterman score: 826; 55.9% identity (73.1% similar) in 238 aa overlap (12-220:99-335)

                                  10        20        30           
pF1KE2                    MALALAALAAVEPACGSRYQQLQNEEESGE-----------
                                     .:. : ::: : :::...:           
NP_061 SSTGVAVGAEHGEDSLSRKPDPEPGRMDHHQPGTG-RYQVLLNEEDNSESSAIEQPPTSN
       70        80        90       100        110       120       

                           40        50        60         70       
pF1KE2 --PE--QAAGDAP--------PPYSSISAESAAYFDYKDESGF-PKPPSYNVATTLPSYD
         :.  :::..::        ::::::..:  .  : .  . : : :: :.:::.::.::
NP_061 PAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYD
       130       140       150       160       170       180       

        80        90            100       110       120       130  
pF1KE2 EAERTKAEATIPLVPG-----RDEDFVGRDDFDDADQLRIGNDGIFMLTFFMAFLFNWIG
       :::..:: :    .       ..:.   ::::.::::::.::::::::.:::::.:::.:
NP_061 EAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFNWLG
       190       200       210       220       230       240       

            140       150       160       170       180       190  
pF1KE2 FFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLF
       : ::::.:.. ::::::: :::::::::::::::: :: :::.:::::::.:::::.:::
NP_061 FCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLF
       250       260       270       280       290       300       

            200       210       220 
pF1KE2 LRGFINYAKVRKMPETFSNLPRTRVLFIY
       .:::.:: :::.: :...   ::: .:. 
NP_061 FRGFVNYLKVRNMSESMAAAHRTRYFFLL
       310       320       330      

>>NP_001154879 (OMIM: 610041) NEDD4 family-interacting p  (316 aa)
 initn: 762 init1: 410 opt: 410  Z-score: 437.5  bits: 88.6 E(85289): 1.2e-17
Smith-Waterman score: 664; 50.0% identity (65.5% similar) in 238 aa overlap (12-220:99-315)

                                  10        20        30           
pF1KE2                    MALALAALAAVEPACGSRYQQLQNEEESGE-----------
                                     .:. : ::: : :::...:           
NP_001 SSTGVAVGAEHGEDSLSRKPDPEPGRMDHHQPGTG-RYQVLLNEEDNSESSAIEQPPTSN
       70        80        90       100        110       120       

                           40        50        60         70       
pF1KE2 --PE--QAAGDAP--------PPYSSISAESAAYFDYKDESGF-PKPPSYNVATTLPSYD
         :.  :::..::        ::::::..:  .  : .  . : : :: :.:::.::.::
NP_001 PAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYD
       130       140       150       160       170       180       

        80        90            100       110       120       130  
pF1KE2 EAERTKAEATIPLVPG-----RDEDFVGRDDFDDADQLRIGNDGIFMLTFFMAFLFNWIG
       :::..:: :    .       ..:.   ::::.::::::.::::::::.::         
NP_001 EAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFF---------
       190       200       210       220       230                 

            140       150       160       170       180       190  
pF1KE2 FFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLF
                  .:::::: :::::::::::::::: :: :::.:::::::.:::::.:::
NP_001 -----------TGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLF
                 240       250       260       270       280       

            200       210       220 
pF1KE2 LRGFINYAKVRKMPETFSNLPRTRVLFIY
       .:::.:: :::.: :...   ::: .:. 
NP_001 FRGFVNYLKVRNMSESMAAAHRTRYFFLL
       290       300       310      




221 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 20:48:17 2016 done: Sat Nov  5 20:48:17 2016
 Total Scan time:  5.480 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]