Result of FASTA (omim) for
pFN21AE2384
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2384, 316 aa
1>>>pF1KE2384 316 - 316 aa - 316 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8597+/-0.000359; mu= 18.8922+/- 0.022
mean_var=71.5265+/-14.443, 0's: 0 Z-trim(113.6): 66 B-trim: 47 in 1/50
Lambda= 0.151649
statistics sampled from 22888 (22956) to 22888 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.269), width: 16
Scan time: 7.530
The best scores are: opt bits E(85289)
NP_001619 (OMIM: 103880) aldose reductase isoform ( 316) 2138 476.8 2.4e-134
NP_064695 (OMIM: 604707) aldo-keto reductase famil ( 316) 1573 353.2 4e-97
XP_011514543 (OMIM: 616336) PREDICTED: aldo-keto r ( 316) 1489 334.9 1.4e-91
XP_016867713 (OMIM: 616336) PREDICTED: aldo-keto r ( 344) 1401 315.6 9e-86
NP_001074007 (OMIM: 616336) aldo-keto reductase fa ( 344) 1401 315.6 9e-86
NP_001333071 (OMIM: 103880) aldose reductase isofo ( 172) 1159 262.4 4.7e-70
XP_005250291 (OMIM: 103880) PREDICTED: aldose redu ( 172) 1159 262.4 4.7e-70
NP_005980 (OMIM: 235555,604741) 3-oxo-5-beta-stero ( 326) 1095 248.7 1.2e-65
NP_001189342 (OMIM: 103830) alcohol dehydrogenase ( 325) 1080 245.4 1.2e-64
NP_001189343 (OMIM: 103830) alcohol dehydrogenase ( 325) 1080 245.4 1.2e-64
NP_697021 (OMIM: 103830) alcohol dehydrogenase [NA ( 325) 1080 245.4 1.2e-64
NP_006057 (OMIM: 103830) alcohol dehydrogenase [NA ( 325) 1080 245.4 1.2e-64
NP_001344 (OMIM: 600449) aldo-keto reductase famil ( 323) 1069 243.0 6.3e-64
NP_995317 (OMIM: 600450,614279) aldo-keto reductas ( 323) 1064 241.9 1.3e-63
NP_001345 (OMIM: 600450,614279) aldo-keto reductas ( 323) 1064 241.9 1.3e-63
NP_001809 (OMIM: 600451,614279) aldo-keto reductas ( 323) 1061 241.2 2.1e-63
NP_001240837 (OMIM: 603966) aldo-keto reductase fa ( 323) 1048 238.4 1.5e-62
NP_003730 (OMIM: 603966) aldo-keto reductase famil ( 323) 1046 237.9 2.1e-62
XP_011514718 (OMIM: 604707) PREDICTED: aldo-keto r ( 277) 1029 234.2 2.4e-61
NP_001177836 (OMIM: 235555,604741) 3-oxo-5-beta-st ( 290) 980 223.5 4.2e-58
XP_011538794 (OMIM: 103830) PREDICTED: alcohol deh ( 214) 663 154.0 2.5e-37
XP_011538793 (OMIM: 103830) PREDICTED: alcohol deh ( 214) 663 154.0 2.5e-37
XP_011514719 (OMIM: 604707) PREDICTED: aldo-keto r ( 175) 645 150.0 3.4e-36
NP_001307956 (OMIM: 600450,614279) aldo-keto reduc ( 297) 609 142.3 1.2e-33
NP_001177835 (OMIM: 235555,604741) 3-oxo-5-beta-st ( 285) 456 108.8 1.4e-23
XP_016871280 (OMIM: 600449) PREDICTED: aldo-keto r ( 297) 394 95.3 1.7e-19
NP_001128713 (OMIM: 600450,614279) aldo-keto reduc ( 139) 382 92.3 6e-19
NP_001240838 (OMIM: 603966) aldo-keto reductase fa ( 138) 369 89.5 4.3e-18
NP_003462 (OMIM: 601141) voltage-gated potassium c ( 408) 145 40.9 0.0054
NP_742128 (OMIM: 601142) voltage-gated potassium c ( 353) 144 40.6 0.0056
XP_005263571 (OMIM: 601142) PREDICTED: voltage-gat ( 353) 144 40.6 0.0056
XP_016858109 (OMIM: 601142) PREDICTED: voltage-gat ( 400) 144 40.7 0.0061
XP_016858108 (OMIM: 601142) PREDICTED: voltage-gat ( 420) 144 40.7 0.0064
XP_016858107 (OMIM: 601142) PREDICTED: voltage-gat ( 420) 144 40.7 0.0064
NP_001186791 (OMIM: 601142) voltage-gated potassiu ( 415) 142 40.3 0.0085
XP_016858110 (OMIM: 601142) PREDICTED: voltage-gat ( 435) 142 40.3 0.0088
>>NP_001619 (OMIM: 103880) aldose reductase isoform 1 [H (316 aa)
initn: 2138 init1: 2138 opt: 2138 Z-score: 2532.8 bits: 476.8 E(85289): 2.4e-134
Smith-Waterman score: 2138; 100.0% identity (100.0% similar) in 316 aa overlap (1-316:1-316)
10 20 30 40 50 60
pF1KE2 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA
250 260 270 280 290 300
310
pF1KE2 LLSCTSHKDYPFHEEF
::::::::::::::::
NP_001 LLSCTSHKDYPFHEEF
310
>>NP_064695 (OMIM: 604707) aldo-keto reductase family 1 (316 aa)
initn: 1613 init1: 1573 opt: 1573 Z-score: 1864.7 bits: 353.2 E(85289): 4e-97
Smith-Waterman score: 1573; 70.6% identity (91.5% similar) in 316 aa overlap (1-316:1-316)
10 20 30 40 50 60
pF1KE2 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ
::. . :.. :::::.:::::::: :.: ::::::::.::::::::.:::::.::: :::
NP_064 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK
::..:..::::.:::::::: :. :. ::. : .:::.::::.:::.:::::: ::: :
NP_064 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP
..:: :..::.. . ...::.: :::::::::::::.:.:::.:.:.: .::::::::::
NP_064 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK
..::.:::::::::::::::.::::.::::::::::::::::::::::::::.:: ::::
NP_064 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA
:.::.::::::: .:::..:::::::: ::.::..::::.::...:.:.::.:::::.:
NP_064 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN
250 260 270 280 290 300
310
pF1KE2 LLSCTSHKDYPFHEEF
.:. . .::::. :.
NP_064 VLQSSHLEDYPFNAEY
310
>>XP_011514543 (OMIM: 616336) PREDICTED: aldo-keto reduc (316 aa)
initn: 1529 init1: 1489 opt: 1489 Z-score: 1765.4 bits: 334.9 E(85289): 1.4e-91
Smith-Waterman score: 1489; 67.4% identity (88.6% similar) in 316 aa overlap (1-316:1-316)
10 20 30 40 50 60
pF1KE2 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ
::. . :.. :::::.:::::.: :.: ::::::::. :::::::. :.:..::: :::
XP_011 MATFVELSTKAKMPIVGLGTWRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK
::..:..: ::.::::::.: :. :. ::. : .:::.::::.:::.:::::: ::: :
XP_011 EKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP
.::: :..::.. . ..::.: :::::::::::::.:.:::::.:.: .::::::::::
XP_011 DFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK
..::.:::::::::::::::.::::.::::::::::::::::::::::::::.:: ::::
XP_011 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA
:.:::::::::: .:::..:::::.:: .:.::..::::.::...:.:.::.:::::.
XP_011 HKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFD
250 260 270 280 290 300
310
pF1KE2 LLSCTSHKDYPFHEEF
. . .:.:: :.
XP_011 FKEFSHLEDFPFDAEY
310
>>XP_016867713 (OMIM: 616336) PREDICTED: aldo-keto reduc (344 aa)
initn: 1408 init1: 1387 opt: 1401 Z-score: 1660.9 bits: 315.6 E(85289): 9e-86
Smith-Waterman score: 1401; 68.4% identity (89.3% similar) in 291 aa overlap (26-316:54-344)
10 20 30 40 50
pF1KE2 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV
:.: ::::::::. :::::::. :.:..::
XP_016 VGPLTGLKSSLLKDTTSAGPLLRPYPASLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEV
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE2 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG
: :::::..:..: ::.::::::.: :. :. ::. : .:::.::::.:::.:::::: :
XP_016 GEAIQEKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE2 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG
:: : .::: :..::.. . ..::.: :::::::::::::.:.:::::.:.: .:::::
XP_016 FKTGDDFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPG
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE2 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIK
:::::..::.:::::::::::::::.::::.::::::::::::::::::::::::::.::
XP_016 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIK
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE2 AIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRN
:::::.:::::::::: .:::..:::::.:: .:.::..::::.::...:.:.::.:::
XP_016 EIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRN
270 280 290 300 310 320
300 310
pF1KE2 WRVCALLSCTSHKDYPFHEEF
::. . . .:.:: :.
XP_016 WRAFDFKEFSHLEDFPFDAEY
330 340
>>NP_001074007 (OMIM: 616336) aldo-keto reductase family (344 aa)
initn: 1408 init1: 1387 opt: 1401 Z-score: 1660.9 bits: 315.6 E(85289): 9e-86
Smith-Waterman score: 1401; 68.4% identity (89.3% similar) in 291 aa overlap (26-316:54-344)
10 20 30 40 50
pF1KE2 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV
:.: ::::::::. :::::::. :.:..::
NP_001 VGPLTGLKSSLLKDTTSAGPLLRPYPASLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEV
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE2 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG
: :::::..:..: ::.::::::.: :. :. ::. : .:::.::::.:::.:::::: :
NP_001 GEAIQEKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE2 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG
:: : .::: :..::.. . ..::.: :::::::::::::.:.:::::.:.: .:::::
NP_001 FKTGDDFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPG
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE2 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIK
:::::..::.:::::::::::::::.::::.::::::::::::::::::::::::::.::
NP_001 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIK
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE2 AIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRN
:::::.:::::::::: .:::..:::::.:: .:.::..::::.::...:.:.::.:::
NP_001 EIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRN
270 280 290 300 310 320
300 310
pF1KE2 WRVCALLSCTSHKDYPFHEEF
::. . . .:.:: :.
NP_001 WRAFDFKEFSHLEDFPFDAEY
330 340
>>NP_001333071 (OMIM: 103880) aldose reductase isoform 2 (172 aa)
initn: 1159 init1: 1159 opt: 1159 Z-score: 1378.7 bits: 262.4 E(85289): 4.7e-70
Smith-Waterman score: 1159; 100.0% identity (100.0% similar) in 172 aa overlap (145-316:1-172)
120 130 140 150 160 170
pF1KE2 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP
::::::::::::::::::::::::::::::
NP_001 MEELVDEGLVKAIGISNFNHLQVEMILNKP
10 20 30
180 190 200 210 220 230
pF1KE2 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRI
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE2 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR
100 110 120 130 140 150
300 310
pF1KE2 NWRVCALLSCTSHKDYPFHEEF
::::::::::::::::::::::
NP_001 NWRVCALLSCTSHKDYPFHEEF
160 170
>>XP_005250291 (OMIM: 103880) PREDICTED: aldose reductas (172 aa)
initn: 1159 init1: 1159 opt: 1159 Z-score: 1378.7 bits: 262.4 E(85289): 4.7e-70
Smith-Waterman score: 1159; 100.0% identity (100.0% similar) in 172 aa overlap (145-316:1-172)
120 130 140 150 160 170
pF1KE2 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP
::::::::::::::::::::::::::::::
XP_005 MEELVDEGLVKAIGISNFNHLQVEMILNKP
10 20 30
180 190 200 210 220 230
pF1KE2 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRI
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE2 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR
100 110 120 130 140 150
300 310
pF1KE2 NWRVCALLSCTSHKDYPFHEEF
::::::::::::::::::::::
XP_005 NWRVCALLSCTSHKDYPFHEEF
160 170
>>NP_005980 (OMIM: 235555,604741) 3-oxo-5-beta-steroid 4 (326 aa)
initn: 1024 init1: 756 opt: 1095 Z-score: 1299.4 bits: 248.7 E(85289): 1.2e-65
Smith-Waterman score: 1095; 50.0% identity (77.0% similar) in 318 aa overlap (4-316:9-326)
10 20 30 40 50
pF1KE2 MASRLLLNNGAKMPILGLGTWK----SPPGQVTEAVKVAIDVGYRHIDCAHVYQN
:. :..: ..::.::::.. .: : . .::::::.:::::: :..:::
NP_005 MDLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 ENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIH
:.::: ::.::. : :.::..: .::: : : .:. . ..:: :.:::.:::.:.
NP_005 EHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 WPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMIL
: .:::: :..: ::.:. . .:. :: ::: : ::::..:.::::. :.:.::
NP_005 VPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELIL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 NKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP-WAKPEDPSLLE
::::::.::. ::.:::::.:: ::...::.. ::.:::::::. : :.. .: ::.
NP_005 NKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 DPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLL
: ..... ..:::.::...:: .::..:::::: . ::: :::..::: :. ..: .
NP_005 DALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIE
250 260 270 280 290 300
300 310
pF1KE2 SYNRNWRVCALLSCTSHKDYPFHEEF
. :.: : :: .: .::::.:.
NP_005 ALNKNVRFVELLMWRDHPEYPFHDEY
310 320
>>NP_001189342 (OMIM: 103830) alcohol dehydrogenase [NAD (325 aa)
initn: 1076 init1: 484 opt: 1080 Z-score: 1281.7 bits: 245.4 E(85289): 1.2e-64
Smith-Waterman score: 1087; 49.5% identity (75.7% similar) in 325 aa overlap (2-316:3-325)
10 20 30 40 50
pF1KE2 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI
:: .::..: :::..::::::: :::: ::: :..::::::::: .: :: :.: :.
NP_001 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 QEKLRE-QVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP
.: . ..: :::::..:::: : :. :. : .:::.::.:.::::::.::: .:.
NP_001 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 GKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY
: . :: . .:.. ..:. .:: :.: :: .:::.:.:.:::: :.. ::. ...
NP_001 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR-
130 140 150 160 170
180 190 200 210 220 230
pF1KE2 KPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIA
::: :.::::::.:..:: .::..:. ::::::::: :: : :..: :::.: . :.:
NP_001 -PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 AKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR-
:.... ::.:.:. .::... ::::.:: :: .:.::::: .: ..: : . :.:::
NP_001 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY
240 250 260 270 280 290
300 310
pF1KE2 VCALLSC--------TSHKDYPFHEEF
. .:. ..: :::.. .
NP_001 IVPMLTVDGKRVPRDAGHPLYPFNDPY
300 310 320
>>NP_001189343 (OMIM: 103830) alcohol dehydrogenase [NAD (325 aa)
initn: 1076 init1: 484 opt: 1080 Z-score: 1281.7 bits: 245.4 E(85289): 1.2e-64
Smith-Waterman score: 1087; 49.5% identity (75.7% similar) in 325 aa overlap (2-316:3-325)
10 20 30 40 50
pF1KE2 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI
:: .::..: :::..::::::: :::: ::: :..::::::::: .: :: :.: :.
NP_001 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 QEKLRE-QVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP
.: . ..: :::::..:::: : :. :. : .:::.::.:.::::::.::: .:.
NP_001 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 GKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY
: . :: . .:.. ..:. .:: :.: :: .:::.:.:.:::: :.. ::. ...
NP_001 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR-
130 140 150 160 170
180 190 200 210 220 230
pF1KE2 KPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIA
::: :.::::::.:..:: .::..:. ::::::::: :: : :..: :::.: . :.:
NP_001 -PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 AKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR-
:.... ::.:.:. .::... ::::.:: :: .:.::::: .: ..: : . :.:::
NP_001 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY
240 250 260 270 280 290
300 310
pF1KE2 VCALLSC--------TSHKDYPFHEEF
. .:. ..: :::.. .
NP_001 IVPMLTVDGKRVPRDAGHPLYPFNDPY
300 310 320
316 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:57:05 2016 done: Mon Nov 7 01:57:06 2016
Total Scan time: 7.530 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]