Result of FASTA (ccds) for
pFN21AE2358
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2358, 421 aa
1>>>pF1KE2358 421 - 421 aa - 421 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5151+/-0.000753; mu= 16.6195+/- 0.045
mean_var=74.8255+/-15.153, 0's: 0 Z-trim(110.1): 15 B-trim: 409 in 1/51
Lambda= 0.148269
statistics sampled from 11362 (11373) to 11362 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.716), E-opt: 0.2 (0.349), width: 16
Scan time: 3.210
The best scores are: opt bits E(32554)
CCDS32117.1 ACOT1 gene_id:641371|Hs108|chr14 ( 421) 2884 626.0 2.1e-179
CCDS9816.1 ACOT2 gene_id:10965|Hs108|chr14 ( 483) 2857 620.3 1.3e-177
CCDS9817.1 ACOT4 gene_id:122970|Hs108|chr14 ( 421) 2089 456.0 3.2e-128
CCDS6752.1 BAAT gene_id:570|Hs108|chr9 ( 418) 1150 255.1 9.3e-68
CCDS32118.1 ACOT6 gene_id:641372|Hs108|chr14 ( 207) 863 193.5 1.6e-49
>>CCDS32117.1 ACOT1 gene_id:641371|Hs108|chr14 (421 aa)
initn: 2884 init1: 2884 opt: 2884 Z-score: 3334.5 bits: 626.0 E(32554): 2.1e-179
Smith-Waterman score: 2884; 100.0% identity (100.0% similar) in 421 aa overlap (1-421:1-421)
10 20 30 40 50 60
pF1KE2 MAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 DLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPDPGRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 DLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPDPGRLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CRVRHERYFLPPGVRREPVRAGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRASLLAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 CRVRHERYFLPPGVRREPVRAGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRASLLAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KGFAVMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSHPEVKGPGVGLLGISKGGELCLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 KGFAVMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSHPEVKGPGVGLLGISKGGELCLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 MASFLKGITAAVVINGSVANVGGTLRYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MASFLKGITAAVVINGSVANVGGTLRYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 EGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 EGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 YIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 YIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSK
370 380 390 400 410 420
pF1KE2 V
:
CCDS32 V
>>CCDS9816.1 ACOT2 gene_id:10965|Hs108|chr14 (483 aa)
initn: 2857 init1: 2857 opt: 2857 Z-score: 3302.4 bits: 620.3 E(32554): 1.3e-177
Smith-Waterman score: 2857; 98.8% identity (100.0% similar) in 421 aa overlap (1-421:63-483)
10 20 30
pF1KE2 MAATLILEPAGRCCWDEPVRIAVRGLAPEQ
::::::::::::::::::::::::::::::
CCDS98 LYQWSLKSSAQFLGSPQLRQVGQIIRVPARMAATLILEPAGRCCWDEPVRIAVRGLAPEQ
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE2 PVTLRASLRDEKGALFQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 PVTLRASLRDEKGALFQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPL
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE2 VRLVKRDVRTPLAVELEVLDGHDPDPGRLLCRVRHERYFLPPGVRREPVRAGRVRGTLFL
:::::::::::::::::::::::::::::::..:::::::::::::::::.:::::::::
CCDS98 VRLVKRDVRTPLAVELEVLDGHDPDPGRLLCQTRHERYFLPPGVRREPVRVGRVRGTLFL
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE2 PPEPGPFPGIVDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 PPEPGPFPGIVDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEE
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE2 AVNYLLSHPEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLRYKGE
:.:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
CCDS98 AMNYLLSHPEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLHYKGE
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE2 TLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 TLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWK
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE2 SEFYANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEPRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 SEFYANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEPRA
400 410 420 430 440 450
400 410 420
pF1KE2 HAMAQVDAWKQLQTFFHKHLGGHEGTIPSKV
:::::::::::::::::::::::::::::::
CCDS98 HAMAQVDAWKQLQTFFHKHLGGHEGTIPSKV
460 470 480
>>CCDS9817.1 ACOT4 gene_id:122970|Hs108|chr14 (421 aa)
initn: 2132 init1: 2079 opt: 2089 Z-score: 2415.4 bits: 456.0 E(32554): 3.2e-128
Smith-Waterman score: 2089; 70.6% identity (89.3% similar) in 419 aa overlap (1-418:1-419)
10 20 30 40 50 60
pF1KE2 MAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGEL
:.::::::: :::::.:::::::::::::: :::::::::::::::.::::: ::. :::
CCDS98 MSATLILEPPGRCCWNEPVRIAVRGLAPEQRVTLRASLRDEKGALFRAHARYCADARGEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 DLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPDPGRLL
:::::::::::::::::::::::::::::. :..::::. :..:::::::::::.:::::
CCDS98 DLERAPALGGSFAGLEPMGLLWALEPEKPFWRFLKRDVQIPFVVELEVLDGHDPEPGRLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CRVRHERYFLPPGVRREPVRAGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRASLLAG
:...:::.::::::::. :::::::.:::::: :::::::.:.:: ::::::::::::::
CCDS98 CQAQHERHFLPPGVRRQSVRAGRVRATLFLPPGPGPFPGIIDIFGIGGGLLEYRASLLAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KGFAVMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSHPEVKGPGVGLLGISKGGELCLS
.:::..::::::.::::..:... :::::::: :.:.::.:::::.:::::: :...:::
CCDS98 HGFATLALAYYNFEDLPNNMDNISLEYFEEAVCYMLQHPQVKGPGIGLLGISLGADICLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 MASFLKGITAAVVINGSVANVGGTLRYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPL
::::::...:.: :::: . . .. :: ..::.: . ::::. .: .::::. :. .
CCDS98 MASFLKNVSATVSINGSGISGNTAINYKHSSIPPLGYDLRRIKVAFSGLVDIVDIRNALV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 EGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGH
: . :.::.:.:.. .:..::::::::.::.::. . .::::::..:::::::: :::
CCDS98 GGYKNPSMIPIEKAQGPILLIVGQDDHNWRSELYAQTVSERLQAHGKEKPQIICYPGTGH
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 YIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGT-IPS
:::::::::: :::: :... .:::::::::. :: :::::. .:: ::::: . : .:
CCDS98 YIEPPYFPLCPASLHRLLNKHVIWGGEPRAHSKAQEDAWKQILAFFCKHLGGTQKTAVPK
370 380 390 400 410 420
420
pF1KE2 KV
CCDS98 L
>>CCDS6752.1 BAAT gene_id:570|Hs108|chr9 (418 aa)
initn: 1171 init1: 543 opt: 1150 Z-score: 1330.0 bits: 255.1 E(32554): 9.3e-68
Smith-Waterman score: 1150; 45.9% identity (72.6% similar) in 401 aa overlap (16-410:14-410)
10 20 30 40 50 60
pF1KE2 MAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGEL
::::.: . :: : : :...:::.::.: .: ..:.:::. .::.
CCDS67 MIQLTATPVSALVDEPVHIRATGLIPFQMVSFQASLEDENGDMFYSQAHYRANEFGEV
10 20 30 40 50
70 80 90 100 110
pF1KE2 DLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRT-PLAVELEVLDGHDPDPGRL
::..: .:::.. :..::::.:.:.::: :.::.:::: . :. :.... : . ...
CCDS67 DLNHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQVQVKLYDLELIVNNKV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 LCRVRH----ERYFLPPGVRREPVRAGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRA
. ::... ::: : :: ::.::.::::: : :::..:.:: :::::.::
CCDS67 ASAPKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGVIDLFGGLGGLLEFRA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 SLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSHPEVKGPGVGLLGISKGG
::::..::: .::::.::::::. :. :::::::.:.:: ::.: : :::.... .:
CCDS67 SLLASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVGVVSVCQGV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 ELCLSMASFLKGITAAVVINGSVANVGGTLRYKGETLPPVGVNRNRIKVTKDGYADIVDV
.. :::: .:: .::.:.:::. : :.:. :. . . :... : .. .
CCDS67 QIGLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNALGLLELYRT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 LNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICY
... : .: : :.:.:.. :::.::. :.. .:. .:..: .:. ::. . .. :
CCDS67 FETTQVGASQYLF-PIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGKNNWTLLSY
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 PETGHYIEPPYFPLCRASL-HALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHE
: .:: ::::: ::: :: : : . :::: :: :: :::..: :..:::
CCDS67 PGAGHLIEPPYSPLCCASTTHDLR---LHWGGEVIPHAAAQEHAWKEIQRFLRKHLIPDV
360 370 380 390 400 410
420
pF1KE2 GTIPSKV
CCDS67 TSQL
>>CCDS32118.1 ACOT6 gene_id:641372|Hs108|chr14 (207 aa)
initn: 875 init1: 855 opt: 863 Z-score: 1002.7 bits: 193.5 E(32554): 1.6e-49
Smith-Waterman score: 863; 57.5% identity (87.0% similar) in 207 aa overlap (215-421:1-207)
190 200 210 220 230 240
pF1KE2 VMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSHPEVKGPGVGLLGISKGGELCLSMASF
.:.::.::::...:::.::::.::::::::
CCDS32 MLQHPKVKGPSIALLGFSKGGDLCLSMASF
10 20 30
250 260 270 280 290 300
pF1KE2 LKGITAAVVINGSVANVGGTLRYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPD
::::::.:.::. :::. . :.:: .: . . ...:.::.:. ..:. ..::: .
CCDS32 LKGITATVLINACVANTVAPLHYKDMIIPKLVDDLGKVKITKSGFLTFMDTWSNPLEEHN
40 50 60 70 80 90
310 320 330 340 350 360
pF1KE2 QKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGHYIEP
..:..:.:.:. :::.::.::..:::::::. : .::::::...::::::::::: :.:
CCDS32 HQSLVPLEKAQVPFLFIVGMDDQSWKSEFYAQIASERLQAHGKERPQIICYPETGHCIDP
100 110 120 130 140 150
370 380 390 400 410 420
pF1KE2 PYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSKV
:::: :::.::..: :..::::.::. ::::::.:.::::::::.:.... ::.
CCDS32 PYFPPSRASVHAVLGEAIFYGGEPKAHSKAQVDAWQQIQTFFHKHLNGKKSVKHSKI
160 170 180 190 200
421 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:22:51 2016 done: Sun Nov 6 12:22:51 2016
Total Scan time: 3.210 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]