Result of FASTA (omim) for
pFN21AE2350
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2350, 446 aa
1>>>pF1KE2350 446 - 446 aa - 446 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3355+/-0.000378; mu= 12.4908+/- 0.023
mean_var=104.6326+/-22.830, 0's: 0 Z-trim(114.4): 141 B-trim: 1181 in 1/53
Lambda= 0.125384
statistics sampled from 24027 (24221) to 24027 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.284), width: 16
Scan time: 9.320
The best scores are: opt bits E(85289)
NP_036585 (OMIM: 605842) transducin beta-like prot ( 447) 2941 543.0 5.9e-154
XP_006715986 (OMIM: 605842) PREDICTED: transducin ( 414) 2661 492.3 9.8e-139
XP_011514329 (OMIM: 605842) PREDICTED: transducin ( 282) 1835 342.8 6.9e-94
NP_620640 (OMIM: 601787) transcription initiation ( 745) 223 51.5 9e-06
NP_001151 (OMIM: 602233) apoptotic protease-activa (1194) 217 50.5 2.8e-05
NP_863658 (OMIM: 602233) apoptotic protease-activa (1205) 217 50.5 2.8e-05
XP_011534221 (OMIM: 612870) PREDICTED: PH-interact (1001) 200 47.4 0.0002
XP_005248786 (OMIM: 612870) PREDICTED: PH-interact (1820) 200 47.6 0.00033
NP_060404 (OMIM: 612870) PH-interacting protein [H (1821) 200 47.6 0.00033
NP_008882 (OMIM: 601787) transcription initiation ( 800) 188 45.2 0.00076
NP_006775 (OMIM: 604737) WD repeat-containing prot ( 943) 178 43.4 0.003
NP_037361 (OMIM: 602233) apoptotic protease-activa (1237) 179 43.7 0.0033
NP_863651 (OMIM: 602233) apoptotic protease-activa (1248) 179 43.7 0.0034
NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 166 40.9 0.0058
>>NP_036585 (OMIM: 605842) transducin beta-like protein (447 aa)
initn: 2941 init1: 2941 opt: 2941 Z-score: 2885.0 bits: 543.0 E(85289): 5.9e-154
Smith-Waterman score: 2941; 99.1% identity (99.3% similar) in 444 aa overlap (1-444:1-444)
10 20 30 40 50 60
pF1KE2 MELSQMSELMGLSVLLGLLALMATAAVARGWLRAGEERSGRPACQKANGFPPDKSSGSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MELSQMSELMGLSVLLGLLALMATAAVARGWLRAGEERSGRPACQKANGFPPDKSSGSKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QKQYQRIRKEKPQQHNFTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTIRIWSTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QKQYQRIRKEKPQQHNFTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTIRIWSTK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DFLQREHRSMRANVELDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGYTFTATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DFLQREHRSMRANVELDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGYTFTATP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EDFPKKHKAPVIDIGIANTGKFIMTASSDTTVLIWSLKGQVLSTINTNQMNNTHAAVSPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EDFPKKHKAPVIDIGIANTGKFIMTASSDTTVLIWSLKGQVLSTINTNQMNNTHAAVSPC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GRFVASCGFTPDVKVWEVCFGKKGEFQEVVRAFELKGHSAAVHSFAFSNDSRRMASVSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GRFVASCGFTPDVKVWEVCFGKKGEFQEVVRAFELKGHSAAVHSFAFSNDSRRMASVSKD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GTWKLWDTDVEYKKKQDPYLLKTGRFEEAAGAAPCRLALSPNAQVLALASGSSIHLYNTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GTWKLWDTDVEYKKKQDPYLLKTGRFEEAAGAAPCRLALSPNAQVLALASGSSIHLYNTR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RGEKEECFERVHGECIANLSFDITGRFLASCGDRAVRLFHNTPGHRAMVEEMQGHLKRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RGEKEECFERVHGECIANLSFDITGRFLASCGDRAVRLFHNTPGHRAMVEEMQGHLKRAS
370 380 390 400 410 420
430 440
pF1KE2 NESTRQRLQQQLTQAQVTLGGPGAED
:::::::::::::::: :: . ::
NP_036 NESTRQRLQQQLTQAQETLKSLGALKK
430 440
>>XP_006715986 (OMIM: 605842) PREDICTED: transducin beta (414 aa)
initn: 2661 init1: 2661 opt: 2661 Z-score: 2611.7 bits: 492.3 E(85289): 9.8e-139
Smith-Waterman score: 2661; 99.0% identity (99.2% similar) in 400 aa overlap (45-444:12-411)
20 30 40 50 60 70
pF1KE2 LLGLLALMATAAVARGWLRAGEERSGRPACQKANGFPPDKSSGSKKQKQYQRIRKEKPQQ
::::::::::::::::::::::::::::::
XP_006 MLTSHPRVLSGQKANGFPPDKSSGSKKQKQYQRIRKEKPQQ
10 20 30 40
80 90 100 110 120 130
pF1KE2 HNFTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTIRIWSTKDFLQREHRSMRANV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HNFTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTIRIWSTKDFLQREHRSMRANV
50 60 70 80 90 100
140 150 160 170 180 190
pF1KE2 ELDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGYTFTATPEDFPKKHKAPVIDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGYTFTATPEDFPKKHKAPVIDI
110 120 130 140 150 160
200 210 220 230 240 250
pF1KE2 GIANTGKFIMTASSDTTVLIWSLKGQVLSTINTNQMNNTHAAVSPCGRFVASCGFTPDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GIANTGKFIMTASSDTTVLIWSLKGQVLSTINTNQMNNTHAAVSPCGRFVASCGFTPDVK
170 180 190 200 210 220
260 270 280 290 300 310
pF1KE2 VWEVCFGKKGEFQEVVRAFELKGHSAAVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VWEVCFGKKGEFQEVVRAFELKGHSAAVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKK
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE2 KQDPYLLKTGRFEEAAGAAPCRLALSPNAQVLALASGSSIHLYNTRRGEKEECFERVHGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQDPYLLKTGRFEEAAGAAPCRLALSPNAQVLALASGSSIHLYNTRRGEKEECFERVHGE
290 300 310 320 330 340
380 390 400 410 420 430
pF1KE2 CIANLSFDITGRFLASCGDRAVRLFHNTPGHRAMVEEMQGHLKRASNESTRQRLQQQLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CIANLSFDITGRFLASCGDRAVRLFHNTPGHRAMVEEMQGHLKRASNESTRQRLQQQLTQ
350 360 370 380 390 400
440
pF1KE2 AQVTLGGPGAED
:: :: . ::
XP_006 AQETLKSLGALKK
410
>>XP_011514329 (OMIM: 605842) PREDICTED: transducin beta (282 aa)
initn: 1835 init1: 1835 opt: 1835 Z-score: 1806.6 bits: 342.8 E(85289): 6.9e-94
Smith-Waterman score: 1835; 98.6% identity (98.9% similar) in 279 aa overlap (166-444:1-279)
140 150 160 170 180 190
pF1KE2 LDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGYTFTATPEDFPKKHKAPVIDIG
::::::::::::::::::::::::::::::
XP_011 MTKREDGGYTFTATPEDFPKKHKAPVIDIG
10 20 30
200 210 220 230 240 250
pF1KE2 IANTGKFIMTASSDTTVLIWSLKGQVLSTINTNQMNNTHAAVSPCGRFVASCGFTPDVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IANTGKFIMTASSDTTVLIWSLKGQVLSTINTNQMNNTHAAVSPCGRFVASCGFTPDVKV
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE2 WEVCFGKKGEFQEVVRAFELKGHSAAVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WEVCFGKKGEFQEVVRAFELKGHSAAVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKK
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE2 QDPYLLKTGRFEEAAGAAPCRLALSPNAQVLALASGSSIHLYNTRRGEKEECFERVHGEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDPYLLKTGRFEEAAGAAPCRLALSPNAQVLALASGSSIHLYNTRRGEKEECFERVHGEC
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE2 IANLSFDITGRFLASCGDRAVRLFHNTPGHRAMVEEMQGHLKRASNESTRQRLQQQLTQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IANLSFDITGRFLASCGDRAVRLFHNTPGHRAMVEEMQGHLKRASNESTRQRLQQQLTQA
220 230 240 250 260 270
440
pF1KE2 QVTLGGPGAED
: :: . ::
XP_011 QETLKSLGALKK
280
>>NP_620640 (OMIM: 601787) transcription initiation fact (745 aa)
initn: 168 init1: 110 opt: 223 Z-score: 224.7 bits: 51.5 E(85289): 9e-06
Smith-Waterman score: 241; 27.4% identity (54.8% similar) in 292 aa overlap (86-361:467-733)
60 70 80 90 100 110
pF1KE2 SGSKKQKQYQRIRKEKPQQHNFTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTIR
:....: .. .: ..... .: : :.:
NP_620 KLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQG-LTAVDVTDDSSLIAGGFADSTVR
440 450 460 470 480 490
120 130 140 150 160 170
pF1KE2 IWSTKDFLQREHRSMRANVELDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGYT
.::. .. ::.. .: . . . : : :. ... :... . : .
NP_620 VWSVT---PKKLRSVKQASDL--SLIDKESDDVLERIMDEKTASELKILYGHSGPVYGAS
500 510 520 530 540 550
180 190 200 210 220
pF1KE2 FT-----ATPEDFPKK----HKAPVIDIGIANTGKFIMTASSDTTVLIWS-LKGQVLSTI
:. :: . : . : : : . ..... :.:.: :: .:. :.:. . :
NP_620 FSPDRLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVR-I
560 570 580 590 600
230 240 250 260 270 280
pF1KE2 NTNQMNNTHA-AVSPCGRFVASCGFTPDVKVWEVCFGKKGEFQEVVRAFELKGHSAAVHS
:.. . :. . :: :::.:. . : .:.. : . . :::::. .: :
NP_620 FTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHG--------LMVGELKGHTDTVCS
610 620 630 640 650 660
290 300 310 320 330 340
pF1KE2 FAFSNDSRRMASVSKDGTWKLWDTDVEYKKKQDPYLLKTGRFEEAAGAAPCRLALSPNAQ
. :: :.. .:: : :.: .:::. : .: :.: : :.: .. : :.:
NP_620 LRFSRDGEILASGSMDNTVRLWDA---IKAFED---LETDDFTTATG----HINLPENSQ
670 680 690 700 710
350 360 370 380 390
pF1KE2 VLALA-----SGSSIHLYNTRRGEKEECFERVHGECIANLSFDITGRFLASCGDRAVRLF
: :. : .::. :::
NP_620 ELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSPQ
720 730 740
>>NP_001151 (OMIM: 602233) apoptotic protease-activating (1194 aa)
initn: 253 init1: 113 opt: 217 Z-score: 215.9 bits: 50.5 E(85289): 2.8e-05
Smith-Waterman score: 217; 27.2% identity (54.5% similar) in 224 aa overlap (185-399:643-855)
160 170 180 190 200 210
pF1KE2 LANGDTLRVFKMTKREDGGYTFTATPEDFPKKHKAPVIDIGIANTGKFIMTASSDTTVLI
: :. :. .... .:: : : : : :
NP_001 SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKI
620 630 640 650 660 670
220 230 240 250 260 270
pF1KE2 W-SLKGQVLSTIN--TNQMNNTHAAVSPCGRFVASCGFTPDVKVWEVCFGKKGEFQEVVR
: :. :... : . ..:.: : . : ..:. . .:.:.. :. :
NP_001 WNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN-------QKECR
680 690 700 710 720
280 290 300 310 320
pF1KE2 AFELKGHSAAVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKK----QDPYLLKTGRFE
. ::. .:. :: :.. .:: : ::: ::::. ..: .. .: :
NP_001 N-TMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQE
730 740 750 760 770 780
330 340 350 360 370 380
pF1KE2 EAAGAAPCRLALSPNAQVLALASGSSIHLYNT-RRGEKEECFERVHGECIANLSFDITGR
. . : . : .. . .:. ..: :.:: :.. .: : : . .. :. :
NP_001 DMEVIVKC-CSWSADGARIMVAAKNKIFLWNTDSRSKVADC--RGHLSWVHGVMFSPDGS
790 800 810 820 830 840
390 400 410 420 430 440
pF1KE2 -FLASCGDRAVRLFHNTPGHRAMVEEMQGHLKRASNESTRQRLQQQLTQAQVTLGGPGAE
::.: :...::.
NP_001 SFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQ
850 860 870 880 890 900
>>NP_863658 (OMIM: 602233) apoptotic protease-activating (1205 aa)
initn: 253 init1: 113 opt: 217 Z-score: 215.8 bits: 50.5 E(85289): 2.8e-05
Smith-Waterman score: 217; 27.2% identity (54.5% similar) in 224 aa overlap (185-399:654-866)
160 170 180 190 200 210
pF1KE2 LANGDTLRVFKMTKREDGGYTFTATPEDFPKKHKAPVIDIGIANTGKFIMTASSDTTVLI
: :. :. .... .:: : : : : :
NP_863 SEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKI
630 640 650 660 670 680
220 230 240 250 260 270
pF1KE2 W-SLKGQVLSTIN--TNQMNNTHAAVSPCGRFVASCGFTPDVKVWEVCFGKKGEFQEVVR
: :. :... : . ..:.: : . : ..:. . .:.:.. :. :
NP_863 WNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN-------QKECR
690 700 710 720 730
280 290 300 310 320
pF1KE2 AFELKGHSAAVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKK----QDPYLLKTGRFE
. ::. .:. :: :.. .:: : ::: ::::. ..: .. .: :
NP_863 N-TMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQE
740 750 760 770 780 790
330 340 350 360 370 380
pF1KE2 EAAGAAPCRLALSPNAQVLALASGSSIHLYNT-RRGEKEECFERVHGECIANLSFDITGR
. . : . : .. . .:. ..: :.:: :.. .: : : . .. :. :
NP_863 DMEVIVKC-CSWSADGARIMVAAKNKIFLWNTDSRSKVADC--RGHLSWVHGVMFSPDGS
800 810 820 830 840 850
390 400 410 420 430 440
pF1KE2 -FLASCGDRAVRLFHNTPGHRAMVEEMQGHLKRASNESTRQRLQQQLTQAQVTLGGPGAE
::.: :...::.
NP_863 SFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQ
860 870 880 890 900 910
>>XP_011534221 (OMIM: 612870) PREDICTED: PH-interacting (1001 aa)
initn: 223 init1: 102 opt: 200 Z-score: 200.3 bits: 47.4 E(85289): 0.0002
Smith-Waterman score: 211; 23.3% identity (54.1% similar) in 296 aa overlap (40-316:131-398)
10 20 30 40 50 60
pF1KE2 MGLSVLLGLLALMATAAVARGWLRAGEERSGRPACQKAN-GFPPDKSSG--SKKQKQYQR
::: . .: : ::. .. :.: . :
XP_011 LGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKYR
110 120 130 140 150 160
70 80 90 100 110 120
pF1KE2 IRKEKPQQHNFTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTIRIWSTKD--FLQ
... : . : . . .: ... :. :. .:. . : .:: ..::.: : .:
XP_011 LERLVPTA-VYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLA
170 180 190 200 210
130 140 150 160 170 180
pF1KE2 --REHRSMRANVELDHATLVRFSPDCRAFI-VW-LANGDTLRVFKMTKREDGGYTFTATP
: : . ... ... . . . .: .: :: : . : :.. :.. . :
XP_011 TLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQ-------GHSASITS
220 230 240 250 260 270
190 200 210 220 230
pF1KE2 EDFPKKHKAPVIDIGIANTGKFIMTASSDTTVLIWSLKGQVLSTINTNQMNNTH------
.: .:. ... ... ....: :. .: . .:. :: . :.
XP_011 LQF-----SPLC----SGSKRYLSSTGADGTICFWLWDAGTLK-INPRPAKFTERPRPGV
280 290 300 310 320
240 250 260 270 280 290
pF1KE2 ----AAVSPCGRFVASCGFTPDVKVWEVCFGKKGEFQEVVRAFELKGHSAAVHSFAFSND
.. : : :.:. . ..:. ::. :. ... ::. :. : :. :::
XP_011 QMICSSFSAGGMFLATGSTDHIIRVY--FFGS-GQPEKIS---ELEFHTDKVDSIQFSNT
330 340 350 360 370
300 310 320 330 340 350
pF1KE2 SRRMASVSKDGTWKLWDTDVEYKKKQDPYLLKTGRFEEAAGAAPCRLALSPNAQVLALAS
: :..: :.::: ..: ..:...
XP_011 SNRFVSGSRDGTARIW----QFKRREWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAW
380 390 400 410 420 430
>>XP_005248786 (OMIM: 612870) PREDICTED: PH-interacting (1820 aa)
initn: 223 init1: 102 opt: 200 Z-score: 196.6 bits: 47.6 E(85289): 0.00033
Smith-Waterman score: 211; 23.3% identity (54.1% similar) in 296 aa overlap (40-316:131-398)
10 20 30 40 50 60
pF1KE2 MGLSVLLGLLALMATAAVARGWLRAGEERSGRPACQKAN-GFPPDKSSG--SKKQKQYQR
::: . .: : ::. .. :.: . :
XP_005 LGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKYR
110 120 130 140 150 160
70 80 90 100 110 120
pF1KE2 IRKEKPQQHNFTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTIRIWSTKD--FLQ
... : . : . . .: ... :. :. .:. . : .:: ..::.: : .:
XP_005 LERLVPTA-VYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLA
170 180 190 200 210
130 140 150 160 170 180
pF1KE2 --REHRSMRANVELDHATLVRFSPDCRAFI-VW-LANGDTLRVFKMTKREDGGYTFTATP
: : . ... ... . . . .: .: :: : . : :.. :.. . :
XP_005 TLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQ-------GHSASITS
220 230 240 250 260 270
190 200 210 220 230
pF1KE2 EDFPKKHKAPVIDIGIANTGKFIMTASSDTTVLIWSLKGQVLSTINTNQMNNTH------
.: .:. ... ... ....: :. .: . .:. :: . :.
XP_005 LQF-----SPLC----SGSKRYLSSTGADGTICFWLWDAGTLK-INPRPAKFTERPRPGV
280 290 300 310 320
240 250 260 270 280 290
pF1KE2 ----AAVSPCGRFVASCGFTPDVKVWEVCFGKKGEFQEVVRAFELKGHSAAVHSFAFSND
.. : : :.:. . ..:. ::. :. ... ::. :. : :. :::
XP_005 QMICSSFSAGGMFLATGSTDHIIRVY--FFGS-GQPEKIS---ELEFHTDKVDSIQFSNT
330 340 350 360 370
300 310 320 330 340 350
pF1KE2 SRRMASVSKDGTWKLWDTDVEYKKKQDPYLLKTGRFEEAAGAAPCRLALSPNAQVLALAS
: :..: :.::: ..: ..:...
XP_005 SNRFVSGSRDGTARIW----QFKRREWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAW
380 390 400 410 420 430
>>NP_060404 (OMIM: 612870) PH-interacting protein [Homo (1821 aa)
initn: 223 init1: 102 opt: 200 Z-score: 196.6 bits: 47.6 E(85289): 0.00033
Smith-Waterman score: 211; 23.3% identity (54.1% similar) in 296 aa overlap (40-316:131-398)
10 20 30 40 50 60
pF1KE2 MGLSVLLGLLALMATAAVARGWLRAGEERSGRPACQKAN-GFPPDKSSG--SKKQKQYQR
::: . .: : ::. .. :.: . :
NP_060 LGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKYR
110 120 130 140 150 160
70 80 90 100 110 120
pF1KE2 IRKEKPQQHNFTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTIRIWSTKD--FLQ
... : . : . . .: ... :. :. .:. . : .:: ..::.: : .:
NP_060 LERLVPTA-VYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLA
170 180 190 200 210
130 140 150 160 170 180
pF1KE2 --REHRSMRANVELDHATLVRFSPDCRAFI-VW-LANGDTLRVFKMTKREDGGYTFTATP
: : . ... ... . . . .: .: :: : . : :.. :.. . :
NP_060 TLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQ-------GHSASITS
220 230 240 250 260 270
190 200 210 220 230
pF1KE2 EDFPKKHKAPVIDIGIANTGKFIMTASSDTTVLIWSLKGQVLSTINTNQMNNTH------
.: .:. ... ... ....: :. .: . .:. :: . :.
NP_060 LQF-----SPLC----SGSKRYLSSTGADGTICFWLWDAGTLK-INPRPAKFTERPRPGV
280 290 300 310 320
240 250 260 270 280 290
pF1KE2 ----AAVSPCGRFVASCGFTPDVKVWEVCFGKKGEFQEVVRAFELKGHSAAVHSFAFSND
.. : : :.:. . ..:. ::. :. ... ::. :. : :. :::
NP_060 QMICSSFSAGGMFLATGSTDHIIRVY--FFGS-GQPEKIS---ELEFHTDKVDSIQFSNT
330 340 350 360 370
300 310 320 330 340 350
pF1KE2 SRRMASVSKDGTWKLWDTDVEYKKKQDPYLLKTGRFEEAAGAAPCRLALSPNAQVLALAS
: :..: :.::: ..: ..:...
NP_060 SNRFVSGSRDGTARIW----QFKRREWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAW
380 390 400 410 420 430
>>NP_008882 (OMIM: 601787) transcription initiation fact (800 aa)
initn: 216 init1: 110 opt: 188 Z-score: 190.0 bits: 45.2 E(85289): 0.00076
Smith-Waterman score: 265; 27.8% identity (51.2% similar) in 320 aa overlap (52-361:501-788)
30 40 50 60 70 80
pF1KE2 MATAAVARGWLRAGEERSGRPACQKANGFPPDKSSGSKKQKQYQRIRKEKPQ-QHNFTHR
: : . :. .. . : ::. . . . .
NP_008 QGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDE
480 490 500 510 520 530
90 100 110 120 130
pF1KE2 LLAAALK---SHSGNISCMDFSSNGKYLATCADDRTIRIWSTKDFLQREHRSMRANVELD
:. :: .::: . .:: . .:: . ..: :.:.:: . : . . :
NP_008 KTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWD
540 550 560 570 580 590
140 150 160 170 180 190
pF1KE2 HATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGYTFTATPEDFPKKHKAPVIDIGIA
..::: :. .: :: .. . : : . : : : .
NP_008 ----TQFSPYGYYFV----SGGHDRVARLWATDH--YQ----PLRIFAGHLADVNCTRFH
600 610 620 630
200 210 220 230 240 250
pF1KE2 NTGKFIMTASSDTTVLIWSLKGQVLSTINTNQMNNTHA-AVSPCGRFVASCGFTPDVKVW
..... :.:.: :: .:.. . : :.. . :. . :: :::.:. . : .:
NP_008 PNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLW
640 650 660 670 680 690
260 270 280 290 300 310
pF1KE2 EVCFGKKGEFQEVVRAFELKGHSAAVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKKQ
.. : . . :::::. .: :. :: :.. .:: : :.: .:::. : .
NP_008 DIGHG--------LMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDA---IKAFE
700 710 720 730 740
320 330 340 350 360 370
pF1KE2 DPYLLKTGRFEEAAGAAPCRLALSPNAQVLALA-----SGSSIHLYNTRRGEKEECFERV
: :.: : :.: .. : :.: : :. : .::. :::
NP_008 D---LETDDFTTATG----HINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYS
750 760 770 780 790
380 390 400 410 420 430
pF1KE2 HGECIANLSFDITGRFLASCGDRAVRLFHNTPGHRAMVEEMQGHLKRASNESTRQRLQQQ
NP_008 PQ
800
446 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:37:34 2016 done: Mon Nov 7 01:37:35 2016
Total Scan time: 9.320 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]