Result of FASTA (ccds) for
pFN21AE2337
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2337, 867 aa
1>>>pF1KE2337 867 - 867 aa - 867 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6559+/-0.00111; mu= 1.3374+/- 0.066
mean_var=229.6621+/-46.367, 0's: 0 Z-trim(109.7): 38 B-trim: 0 in 0/52
Lambda= 0.084631
statistics sampled from 11080 (11098) to 11080 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.341), width: 16
Scan time: 3.930
The best scores are: opt bits E(32554)
CCDS7849.1 E2F8 gene_id:79733|Hs108|chr11 ( 867) 5678 707.0 3.6e-203
CCDS9016.1 E2F7 gene_id:144455|Hs108|chr12 ( 911) 911 125.0 6e-28
>>CCDS7849.1 E2F8 gene_id:79733|Hs108|chr11 (867 aa)
initn: 5678 init1: 5678 opt: 5678 Z-score: 3761.1 bits: 707.0 E(32554): 3.6e-203
Smith-Waterman score: 5678; 100.0% identity (100.0% similar) in 867 aa overlap (1-867:1-867)
10 20 30 40 50 60
pF1KE2 MENEKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKEGSQGEPWTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 MENEKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKEGSQGEPWTPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ANLKMLISAVSPEIRNRDQKRGLFDNRSGLPEAKDCIHEHLSGDEFEKSQPSRKEKSLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 ANLKMLISAVSPEIRNRDQKRGLFDNRSGLPEAKDCIHEHLSGDEFEKSQPSRKEKSLGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 LCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 HGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKSYSIEDHIIKSNTGPNGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 HGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKSYSIEDHIIKSNTGPNGH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 PDMCFVELPGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 PDMCFVELPGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 EDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 EDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 IHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 IHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 TNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 TNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 AEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 SPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 ERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 ERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 SALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 SALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALAS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 SHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 RATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 RATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMD
790 800 810 820 830 840
850 860
pF1KE2 FEGANKTSLGTLFVPQRKLEVSTEDVH
:::::::::::::::::::::::::::
CCDS78 FEGANKTSLGTLFVPQRKLEVSTEDVH
850 860
>>CCDS9016.1 E2F7 gene_id:144455|Hs108|chr12 (911 aa)
initn: 1206 init1: 499 opt: 911 Z-score: 615.2 bits: 125.0 E(32554): 6e-28
Smith-Waterman score: 1401; 37.3% identity (61.1% similar) in 934 aa overlap (2-863:27-907)
10 20 30
pF1KE2 MEN-EKENLFCEPHKRGLMKTPLKESTTANIVLAE
:: .:::.: . ..: :::.:. .
CCDS90 MEVNCLTLKDLISPRQPRLDFAVEDGENAQKENIFVD-RSRMAPKTPIKNEPIDLSKQKK
10 20 30 40 50
40 50 60 70 80 90
pF1KE2 IQPDFGPLTTPTKPKEGSQGEPWTPTANLKMLISAVSPEIRNRDQKRGLFDNRSGLPEA-
. :. .:.: :.: . .:.:::::::::::::::.::.::.:..:.::: . .:
CCDS90 FTPERNPIT-PVKFVDRQQAEPWTPTANLKMLISAASPDIRDREKKKGLFRPIENKDDAF
60 70 80 90 100 110
100 110 120 130 140
pF1KE2 KDCIHEHLSGD----EFEKSQPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEE
: .. . :: ::::..::::.:::::::.:::::::.:: . .. : :::::
CCDS90 TDSLQLDVVGDSAVDEFEKQRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVS
120 130 140 150 160 170
150 160 170 180 190 200
pF1KE2 LNVERRRIYDIVNVLESLHMVSRLAKNRYTWHGRHNLNKTLGTLKSIGEENKYAEQIMMI
:.:::::::::::::::::.:::.:::.: :::::.: ::: .:. .:::.:: ::. ..
CCDS90 LGVERRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLPKTLRNLQRLGEEQKYEEQMAYL
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE2 KKKEYEQEFDFIKSYSIEDHIIKSNTGPNGHPDMCFVELPGVEFRAASVNSRKDKSLRVM
..: :.:.: .:.. .. :.. :... .. .... . ..:.:::::::::.:
CCDS90 QQK----ELDLI-DYKFGER--KKDGDPDSQEQQ-LLDFSEPDCPSSSANSRKDKSLRIM
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE2 SQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRRLYDIANVLSSLDLIK
::::::::::: .::.:.::::::: :. . :.::::::.::::::::::.:: :::
CCDS90 SQKFVMLFLVSKTKIVTLDVAAKILI-EESQDAPDHSKFKTKVRRLYDIANVLTSLALIK
300 310 320 330 340
330 340 350 360 370 380
pF1KE2 KVHVTEERGRKPAFKWTGPEISPNTSGSSPVIHFTPSDL-EVRRSSK---ENCAKNLFST
:::::::::::::::: :: .:.. .. . : : :..: . . :::.
CCDS90 KVHVTEERGRKPAFKWIGP--VDFSSSDEELVDVSASVLPELKRETYGQIQVCAKQ----
350 360 370 380 390 400
390 400 410 420 430 440
pF1KE2 RGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICK
...:: :. . :.. : .::.:: :::: . . :.:. . ....:::. .
CCDS90 ----KLARHGSF-NTVQASERIQRKVNSEPSSPYREE-----QGSGGYSLEIGSLAAVYR
410 420 430 440 450
450 460 470 480 490
pF1KE2 MQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPL------
...:..:. . : . :. ::::. : .... : . : .:. :
CCDS90 QKIEDNSQGKAFASKRVVPPSSSLDPVAPF-PVLSVDPEYCVNPLAHPVFSVAQTDLQAF
460 470 480 490 500 510
500 510 520 530 540 550
pF1KE2 -IPSPLSSAVPLILPQAPSGPSYAIYLQPTQ-AHQSVT--PPQGLSPTVCTTHSSKATGS
. . :.. : . : .: :. :.:. : : .. : .: . . . :.::
CCDS90 SMQNGLNGQVDVSLASAASAVES---LKPALLAGQPLVYVPSASLFMLYGSLQEGPASGS
520 530 540 550 560
560 570 580 590 600
pF1KE2 KDSTDATTEKAANDTSKASASTRPGSLL----PAPERQGAKSR-TRE----PAGERGSKR
. : . .: . .:: . : : : . : .: .:: : . :.
CCDS90 GSERDDRSSEAPATVELSSAPSAQKRLCEERKPQEEDEPATKRQSREYEDGPLSLVMPKK
570 580 590 600 610 620
610 620 630 640 650
pF1KE2 ASMLEDSGSKKKFKE----DLKGLE---NVSATLFPSGYLIPLTQCSS-LGAESILS---
: : .: : . . :: .. .. :. :: . :: : : .
CCDS90 PSDSTDLASPKTMGNRASIPLKDIHVNGQLPAAEEISGKATANSLVSSEWGNPSRNTDVE
630 640 650 660 670 680
660 670 680 690 700
pF1KE2 --GKENSSALSPNHRIY---SSPIAGV----IPVTSSEL------TAVNFPSFHVTPLKL
.::: :. :. : .:: ::. . ...:. .. ..::: : : .
CCDS90 KPSKENESTKEPSLLQYLCVQSP-AGLNGFNVLLSGSQTPPTVGPSSGQLPSFSV-PCMV
690 700 710 720 730 740
710 720 730 740 750
pF1KE2 MVSPTSVAAVPVGNSPALASSHPVPIQN-----PSSAIVNFTLQHLGLISPNVQLSASPG
. :: .. :: :::. : :... :... :::.: :: :. :: ..:
CCDS90 LPSPP-LGPFPVLYSPAM----PGPVSSTLGALPNTGPVNFSLPGLGSIA---QLLVGPT
750 760 770 780 790
760 770 780 790 800
pF1KE2 SGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQS-----QPN-----GQSVAVTGA
. . : : . :.. :. :.. . ::: ..: ::. :. :.:.
CCDS90 AVVNPKSSTLPSAD--PQ----LQSQPSLNLSPVMSRSHSVVQQPESPVYVGHPVSVVKL
800 810 820 830 840 850
810 820 830 840 850 860
pF1KE2 QQ-PVPVTPKGSQLVA-ESFFRTPGGPTKPTSSSCMDFEGANKTSLGTLFVPQRKLEVST
.: :::::::. : . :.::.:::. :. . .. : .: ::.::. .
CCDS90 HQSPVPVTPKSIQRTHRETFFKTPGSLGDPVLKRRERNQSRNTSS------AQRRLEIPS
860 870 880 890 900
pF1KE2 EDVH
CCDS90 GGAD
910
867 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:13:44 2016 done: Sun Nov 6 15:13:44 2016
Total Scan time: 3.930 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]