Result of FASTA (omim) for
pFN21AE2316
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2316, 398 aa
1>>>pF1KE2316 398 - 398 aa - 398 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9686+/-0.000297; mu= 19.0495+/- 0.019
mean_var=64.3943+/-13.067, 0's: 0 Z-trim(117.2): 34 B-trim: 150 in 2/50
Lambda= 0.159827
statistics sampled from 28909 (28950) to 28909 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.339), width: 16
Scan time: 7.430
The best scores are: opt bits E(85289)
NP_443168 (OMIM: 300663) cysteine protease ATG4A i ( 398) 2751 642.7 4.4e-184
NP_001308216 (OMIM: 300663) cysteine protease ATG4 ( 321) 2227 521.9 8.8e-148
NP_840055 (OMIM: 300663) cysteine protease ATG4A i ( 321) 2227 521.9 8.8e-148
NP_001308217 (OMIM: 300663) cysteine protease ATG4 ( 321) 2227 521.9 8.8e-148
XP_011529144 (OMIM: 300663) PREDICTED: cysteine pr ( 321) 2227 521.9 8.8e-148
NP_001308219 (OMIM: 300663) cysteine protease ATG4 ( 226) 1546 364.7 1.2e-100
NP_037457 (OMIM: 611338) cysteine protease ATG4B i ( 393) 1502 354.7 2.2e-97
XP_016859127 (OMIM: 611338) PREDICTED: cysteine pr ( 457) 1502 354.8 2.4e-97
NP_847896 (OMIM: 611338) cysteine protease ATG4B i ( 380) 1462 345.5 1.3e-94
XP_005247050 (OMIM: 611338) PREDICTED: cysteine pr ( 405) 1462 345.5 1.3e-94
XP_005247049 (OMIM: 611338) PREDICTED: cysteine pr ( 415) 1462 345.5 1.4e-94
XP_016859126 (OMIM: 611338) PREDICTED: cysteine pr ( 479) 1462 345.6 1.5e-94
NP_840054 (OMIM: 300663) cysteine protease ATG4A i ( 336) 1457 344.3 2.5e-94
XP_011529143 (OMIM: 300663) PREDICTED: cysteine pr ( 340) 1444 341.3 2.1e-93
XP_016859129 (OMIM: 611338) PREDICTED: cysteine pr ( 319) 1218 289.2 9.5e-78
XP_005247053 (OMIM: 611338) PREDICTED: cysteine pr ( 319) 1218 289.2 9.5e-78
XP_016859128 (OMIM: 611338) PREDICTED: cysteine pr ( 341) 1178 280.0 6e-75
XP_005247052 (OMIM: 611338) PREDICTED: cysteine pr ( 341) 1178 280.0 6e-75
NP_001308218 (OMIM: 300663) cysteine protease ATG4 ( 259) 933 223.4 4.9e-58
XP_006722990 (OMIM: 611340) PREDICTED: cysteine pr ( 360) 352 89.5 1.3e-17
XP_005271345 (OMIM: 611339) PREDICTED: cysteine pr ( 458) 349 88.9 2.6e-17
NP_835739 (OMIM: 611339) cysteine protease ATG4C [ ( 458) 349 88.9 2.6e-17
NP_116241 (OMIM: 611339) cysteine protease ATG4C [ ( 458) 349 88.9 2.6e-17
XP_011540615 (OMIM: 611339) PREDICTED: cysteine pr ( 423) 326 83.6 9.8e-16
NP_001268433 (OMIM: 611340) cysteine protease ATG4 ( 411) 256 67.5 6.9e-11
NP_116274 (OMIM: 611340) cysteine protease ATG4D i ( 474) 256 67.5 7.7e-11
XP_016858090 (OMIM: 611339) PREDICTED: cysteine pr ( 418) 218 58.7 3e-08
XP_016858089 (OMIM: 611339) PREDICTED: cysteine pr ( 418) 218 58.7 3e-08
>>NP_443168 (OMIM: 300663) cysteine protease ATG4A isofo (398 aa)
initn: 2751 init1: 2751 opt: 2751 Z-score: 3425.8 bits: 642.7 E(85289): 4.4e-184
Smith-Waterman score: 2751; 100.0% identity (100.0% similar) in 398 aa overlap (1-398:1-398)
10 20 30 40 50 60
pF1KE2 MESVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 MESVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 FSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 RKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 DIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 VDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 HCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 HCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWP
310 320 330 340 350 360
370 380 390
pF1KE2 PFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV
::::::::::::::::::::::::::::::::::::::
NP_443 PFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV
370 380 390
>>NP_001308216 (OMIM: 300663) cysteine protease ATG4A is (321 aa)
initn: 2227 init1: 2227 opt: 2227 Z-score: 2774.2 bits: 521.9 E(85289): 8.8e-148
Smith-Waterman score: 2227; 100.0% identity (100.0% similar) in 321 aa overlap (78-398:1-321)
50 60 70 80 90 100
pF1KE2 DISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQ
::::::::::::::::::::::::::::::
NP_001 MLRCGQMMLAQALICRHLGRDWSWEKQKEQ
10 20 30
110 120 130 140 150 160
pF1KE2 PKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSL
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE2 AVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE2 PLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFV
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE2 DTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLR
220 230 240 250 260 270
350 360 370 380 390
pF1KE2 MFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV
280 290 300 310 320
>>NP_840055 (OMIM: 300663) cysteine protease ATG4A isofo (321 aa)
initn: 2227 init1: 2227 opt: 2227 Z-score: 2774.2 bits: 521.9 E(85289): 8.8e-148
Smith-Waterman score: 2227; 100.0% identity (100.0% similar) in 321 aa overlap (78-398:1-321)
50 60 70 80 90 100
pF1KE2 DISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQ
::::::::::::::::::::::::::::::
NP_840 MLRCGQMMLAQALICRHLGRDWSWEKQKEQ
10 20 30
110 120 130 140 150 160
pF1KE2 PKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_840 PKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSL
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE2 AVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_840 AVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE2 PLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_840 PLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFV
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE2 DTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_840 DTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLR
220 230 240 250 260 270
350 360 370 380 390
pF1KE2 MFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_840 MFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV
280 290 300 310 320
>>NP_001308217 (OMIM: 300663) cysteine protease ATG4A is (321 aa)
initn: 2227 init1: 2227 opt: 2227 Z-score: 2774.2 bits: 521.9 E(85289): 8.8e-148
Smith-Waterman score: 2227; 100.0% identity (100.0% similar) in 321 aa overlap (78-398:1-321)
50 60 70 80 90 100
pF1KE2 DISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQ
::::::::::::::::::::::::::::::
NP_001 MLRCGQMMLAQALICRHLGRDWSWEKQKEQ
10 20 30
110 120 130 140 150 160
pF1KE2 PKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSL
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE2 AVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE2 PLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFV
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE2 DTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLR
220 230 240 250 260 270
350 360 370 380 390
pF1KE2 MFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV
280 290 300 310 320
>>XP_011529144 (OMIM: 300663) PREDICTED: cysteine protea (321 aa)
initn: 2227 init1: 2227 opt: 2227 Z-score: 2774.2 bits: 521.9 E(85289): 8.8e-148
Smith-Waterman score: 2227; 100.0% identity (100.0% similar) in 321 aa overlap (78-398:1-321)
50 60 70 80 90 100
pF1KE2 DISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQ
::::::::::::::::::::::::::::::
XP_011 MLRCGQMMLAQALICRHLGRDWSWEKQKEQ
10 20 30
110 120 130 140 150 160
pF1KE2 PKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSL
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE2 AVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE2 PLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFV
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE2 DTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLR
220 230 240 250 260 270
350 360 370 380 390
pF1KE2 MFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV
280 290 300 310 320
>>NP_001308219 (OMIM: 300663) cysteine protease ATG4A is (226 aa)
initn: 1546 init1: 1546 opt: 1546 Z-score: 1927.7 bits: 364.7 E(85289): 1.2e-100
Smith-Waterman score: 1546; 100.0% identity (100.0% similar) in 226 aa overlap (173-398:1-226)
150 160 170 180 190 200
pF1KE2 GEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPD
::::::::::::::::::::::::::::::
NP_001 MDNTVVIEDIKKMCRVLPLSADTAGDRPPD
10 20 30
210 220 230 240 250 260
pF1KE2 SLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGALGGKPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGALGGKPN
40 50 60 70 80 90
270 280 290 300 310 320
pF1KE2 NAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGF
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE2 FCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTE
160 170 180 190 200 210
390
pF1KE2 QLEEFDLEEDFEILSV
::::::::::::::::
NP_001 QLEEFDLEEDFEILSV
220
>>NP_037457 (OMIM: 611338) cysteine protease ATG4B isofo (393 aa)
initn: 1512 init1: 877 opt: 1502 Z-score: 1869.4 bits: 354.7 E(85289): 2.2e-97
Smith-Waterman score: 1502; 55.8% identity (80.3% similar) in 391 aa overlap (15-398:13-393)
10 20 30 40 50 60
pF1KE2 MESVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRK
:... :..:.:.: :::::... . :::...:::...:::::::..
NP_037 MDAATLTYDTLRFAEF-EDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKN
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 FSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLD
: ::::::.::.:::::::::::..::::.:::::::: : ..:.:: : .:. :.:
NP_037 FPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFID
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 RKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIE
::: :::::.::::::::::::.:.:::::::::::::.:: :.::::...::::::.:
NP_037 RKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVME
120 130 140 150 160 170
190 200 210 220 230
pF1KE2 DIKKMCRV-LPLSADTAGDRPPDSLTASN---QSKGTSAYCSAWKPLLLIVPLRLGINQI
.:...::. .: .. :: : :: : . .. : :.::.:..:::::...:
NP_037 EIRRLCRTSVPCAGATA--FPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 NPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVN
: .::...:.:: ::::::..:::::.:.::::..:.:::.::::::: :. .. .
NP_037 NEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 DQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQK-EILKENLRMFELVQKH
:..::: . : ::.: .::::.:.::::: : ::..::. :.: .: : :::::. .
NP_037 DESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQ
300 310 320 330 340 350
360 370 380 390
pF1KE2 PSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEF-DLE-EDFEILSV
::: : :.: . . . : .:.::.: : : :::::::.
NP_037 PSHL------ACPDVLNLSLDSSD-VERLERFFDSEDEDFEILSL
360 370 380 390
>>XP_016859127 (OMIM: 611338) PREDICTED: cysteine protea (457 aa)
initn: 1512 init1: 877 opt: 1502 Z-score: 1868.5 bits: 354.8 E(85289): 2.4e-97
Smith-Waterman score: 1502; 55.8% identity (80.3% similar) in 391 aa overlap (15-398:77-457)
10 20 30 40
pF1KE2 MESVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSK
:... :..:.:.: :::::... . :::..
XP_016 YGTDTMATMTVCSAPGGSGCVATLTYDTLRFAEF-EDFPETSEPVWILGRKYSIFTEKDE
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE2 LLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQ
.:::...:::::::..: ::::::.::.:::::::::::..::::.:::::::: : ..
XP_016 ILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQR
110 120 130 140 150 160
110 120 130 140 150 160
pF1KE2 KEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEW
:.:: : .:. :.:::: :::::.::::::::::::.:.:::::::::::::.:: :
XP_016 KRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTW
170 180 190 200 210 220
170 180 190 200 210 220
pF1KE2 NSLAVYVSMDNTVVIEDIKKMCRV-LPLSADTAGDRPPDSLTASN---QSKGTSAYCSAW
.::::...::::::.:.:...::. .: .. :: : :: : . .. : :
XP_016 SSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATA--FPADSDRHCNGFPAGAEVTNRPSPW
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE2 KPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDP
.::.:..:::::...:: .::...:.:: ::::::..:::::.:.::::..:.:::.:::
XP_016 RPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDP
290 300 310 320 330 340
290 300 310 320 330
pF1KE2 HTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQK-
:::: :. .. . :..::: . : ::.: .::::.:.::::: : ::..::. :.:
XP_016 HTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKL
350 360 370 380 390 400
340 350 360 370 380 390
pF1KE2 EILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEF-DLE-EDFEILS
.: : :::::. .::: : :.: . . . : .:.::.: : : :::::::
XP_016 SLLGGALPMFELVELQPSHL------ACPDVLNLSLDSSD-VERLERFFDSEDEDFEILS
410 420 430 440 450
pF1KE2 V
.
XP_016 L
>>NP_847896 (OMIM: 611338) cysteine protease ATG4B isofo (380 aa)
initn: 1482 init1: 877 opt: 1462 Z-score: 1819.8 bits: 345.5 E(85289): 1.3e-94
Smith-Waterman score: 1462; 57.6% identity (82.8% similar) in 349 aa overlap (15-358:13-358)
10 20 30 40 50 60
pF1KE2 MESVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRK
:... :..:.:.: :::::... . :::...:::...:::::::..
NP_847 MDAATLTYDTLRFAEF-EDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKN
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 FSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLD
: ::::::.::.:::::::::::..::::.:::::::: : ..:.:: : .:. :.:
NP_847 FPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFID
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 RKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIE
::: :::::.::::::::::::.:.:::::::::::::.:: :.::::...::::::.:
NP_847 RKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVME
120 130 140 150 160 170
190 200 210 220 230
pF1KE2 DIKKMCRV-LPLSADTAGDRPPDSLTASN---QSKGTSAYCSAWKPLLLIVPLRLGINQI
.:...::. .: .. :: : :: : . .. : :.::.:..:::::...:
NP_847 EIRRLCRTSVPCAGATA--FPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 NPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVN
: .::...:.:: ::::::..:::::.:.::::..:.:::.::::::: :. .. .
NP_847 NEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 DQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQK-EILKENLRMFELVQKH
:..::: . : ::.: .::::.:.::::: : ::..::. :.: .: : :::::. .
NP_847 DESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQ
300 310 320 330 340 350
360 370 380 390
pF1KE2 PSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV
:::
NP_847 PSHLACPDVLNLSLGESCQVQILLM
360 370 380
>>XP_005247050 (OMIM: 611338) PREDICTED: cysteine protea (405 aa)
initn: 1512 init1: 877 opt: 1462 Z-score: 1819.4 bits: 345.5 E(85289): 1.3e-94
Smith-Waterman score: 1487; 55.1% identity (79.5% similar) in 396 aa overlap (15-398:13-405)
10 20 30 40 50 60
pF1KE2 MESVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRK
:... :..:.:.: :::::... . :::...:::...:::::::..
XP_005 MDAATLTYDTLRFAEF-EDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKN
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 FSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLD
: ::::::.::.:::::::::::..::::.:::::::: : ..:.:: : .:. :.:
XP_005 FPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFID
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 RKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIE
::: :::::.::::::::::::.:.:::::::::::::.:: :.::::...::::::.:
XP_005 RKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVME
120 130 140 150 160 170
190 200 210 220 230
pF1KE2 DIKKMCRV-LPLSADTAGDRPPDSLTASN---QSKGTSAYCSAWKPLLLIVPLRLGINQI
.:...::. .: .. :: : :: : . .. : :.::.:..:::::...:
XP_005 EIRRLCRTSVPCAGATA--FPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 NPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVN
: .::...:.:: ::::::..:::::.:.::::..:.:::.::::::: :. .. .
XP_005 NEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 DQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQK-EILKENLRMFELVQKH
:..::: . : ::.: .::::.:.::::: : ::..::. :.: .: : :::::. .
XP_005 DESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQ
300 310 320 330 340 350
360 370 380 390
pF1KE2 PSHW--PPFVPPAKPEVTTTGAEFI-DST--EQLEEF-DLE-EDFEILSV
::: : . . : . . . ::. :.::.: : : :::::::.
XP_005 PSHLACPDVLNLSLGESCQVQVGSLGDSSDVERLERFFDSEDEDFEILSL
360 370 380 390 400
398 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:45:24 2016 done: Sun Nov 6 12:45:25 2016
Total Scan time: 7.430 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]