Result of FASTA (omim) for
pFN21AE2297
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2297, 1660 aa
1>>>pF1KE2297 1660 - 1660 aa - 1660 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.9085+/-0.000468; mu= -15.9562+/- 0.029
mean_var=596.4002+/-123.988, 0's: 0 Z-trim(122.7): 111 B-trim: 0 in 0/60
Lambda= 0.052518
statistics sampled from 41267 (41386) to 41267 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.485), width: 16
Scan time: 19.570
The best scores are: opt bits E(85289)
XP_016859056 (OMIM: 613555) PREDICTED: methylcytos (1702) 11461 885.0 0
XP_011530988 (OMIM: 613555) PREDICTED: methylcytos (1776) 11461 885.1 0
XP_005264244 (OMIM: 613555) PREDICTED: methylcytos (1795) 11461 885.1 0
NP_001274420 (OMIM: 613555) methylcytosine dioxyge (1795) 11461 885.1 0
XP_011530989 (OMIM: 613555) PREDICTED: methylcytos (1718) 6454 505.7 1.5e-141
XP_011530987 (OMIM: 613555) PREDICTED: methylcytos (1792) 6454 505.7 1.5e-141
XP_011530984 (OMIM: 613555) PREDICTED: methylcytos (1811) 6454 505.7 1.5e-141
XP_011530986 (OMIM: 613555) PREDICTED: methylcytos (1811) 6454 505.7 1.5e-141
XP_011530985 (OMIM: 613555) PREDICTED: methylcytos (1811) 6454 505.7 1.5e-141
XP_016859055 (OMIM: 613555) PREDICTED: methylcytos (1811) 6454 505.7 1.5e-141
XP_011530990 (OMIM: 613555) PREDICTED: methylcytos (1050) 6286 492.8 6.9e-138
XP_011530992 (OMIM: 613555) PREDICTED: methylcytos ( 953) 5227 412.5 9.1e-114
XP_011530991 (OMIM: 613555) PREDICTED: methylcytos ( 953) 5227 412.5 9.1e-114
NP_001120680 (OMIM: 612839,614286) methylcytosine (2002) 2045 171.7 5.9e-41
XP_005263139 (OMIM: 612839,614286) PREDICTED: meth (2002) 2045 171.7 5.9e-41
NP_085128 (OMIM: 607790) methylcytosine dioxygenas (2136) 1727 147.6 1.1e-33
XP_006714305 (OMIM: 612839,614286) PREDICTED: meth (1902) 1123 101.8 6.1e-20
XP_011538509 (OMIM: 607790) PREDICTED: methylcytos (1494) 1076 98.1 6e-19
XP_016872178 (OMIM: 607790) PREDICTED: methylcytos (1494) 1076 98.1 6e-19
XP_016872177 (OMIM: 607790) PREDICTED: methylcytos (1512) 1076 98.2 6.1e-19
XP_016872176 (OMIM: 607790) PREDICTED: methylcytos (1512) 1076 98.2 6.1e-19
XP_016872175 (OMIM: 607790) PREDICTED: methylcytos (1516) 1076 98.2 6.1e-19
XP_011538507 (OMIM: 607790) PREDICTED: methylcytos (1528) 1076 98.2 6.1e-19
XP_011538506 (OMIM: 607790) PREDICTED: methylcytos (2165) 1076 98.3 7.9e-19
XP_011538508 (OMIM: 607790) PREDICTED: methylcytos (1501) 459 51.4 7.1e-05
XP_011536691 (OMIM: 601234) PREDICTED: nascent pol (2078) 396 46.8 0.0025
XP_006719476 (OMIM: 601234) PREDICTED: nascent pol (2082) 396 46.8 0.0025
XP_006719477 (OMIM: 601234) PREDICTED: nascent pol (2082) 396 46.8 0.0025
XP_006719475 (OMIM: 601234) PREDICTED: nascent pol (2082) 396 46.8 0.0025
NP_001121182 (OMIM: 208250,604283) proteoglycan 4 (1270) 382 45.5 0.0036
XP_016855492 (OMIM: 208250,604283) PREDICTED: prot (1270) 382 45.5 0.0036
XP_016855491 (OMIM: 208250,604283) PREDICTED: prot (1311) 382 45.5 0.0037
NP_001121181 (OMIM: 208250,604283) proteoglycan 4 (1311) 382 45.5 0.0037
NP_001290161 (OMIM: 208250,604283) proteoglycan 4 (1361) 382 45.5 0.0038
NP_001121180 (OMIM: 208250,604283) proteoglycan 4 (1363) 382 45.5 0.0038
NP_005798 (OMIM: 208250,604283) proteoglycan 4 iso (1404) 382 45.5 0.0039
>>XP_016859056 (OMIM: 613555) PREDICTED: methylcytosine (1702 aa)
initn: 11461 init1: 11461 opt: 11461 Z-score: 4712.8 bits: 885.0 E(85289): 0
Smith-Waterman score: 11461; 100.0% identity (100.0% similar) in 1660 aa overlap (1-1660:43-1702)
10 20 30
pF1KE2 MDSGPVYHGDSRQLSASGVPVNGAREPAGP
::::::::::::::::::::::::::::::
XP_016 AGEGAGPWGQGAAVKTGSELSPVDGPVPGQMDSGPVYHGDSRQLSASGVPVNGAREPAGP
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE2 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE2 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE2 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE2 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE2 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE2 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE2 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
440 450 460 470 480 490
460 470 480 490 500 510
pF1KE2 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
500 510 520 530 540 550
520 530 540 550 560 570
pF1KE2 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
560 570 580 590 600 610
580 590 600 610 620 630
pF1KE2 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
620 630 640 650 660 670
640 650 660 670 680 690
pF1KE2 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
680 690 700 710 720 730
700 710 720 730 740 750
pF1KE2 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
740 750 760 770 780 790
760 770 780 790 800 810
pF1KE2 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
800 810 820 830 840 850
820 830 840 850 860 870
pF1KE2 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
860 870 880 890 900 910
880 890 900 910 920 930
pF1KE2 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQVTNEEIAIDCRLGLKEGRPFAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQVTNEEIAIDCRLGLKEGRPFAG
920 930 940 950 960 970
940 950 960 970 980 990
pF1KE2 VTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQLHVLPLYKMANTDEFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQLHVLPLYKMANTDEFG
980 990 1000 1010 1020 1030
1000 1010 1020 1030 1040 1050
pF1KE2 SEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKAAAEKKKIQKEKLSTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKAAAEKKKIQKEKLSTPE
1040 1050 1060 1070 1080 1090
1060 1070 1080 1090 1100 1110
pF1KE2 KIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSFKYSGNAVVESYSVLGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSFKYSGNAVVESYSVLGN
1100 1110 1120 1130 1140 1150
1120 1130 1140 1150 1160 1170
pF1KE2 CRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGFPSSNPVFPSQFLGPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGFPSSNPVFPSQFLGPGA
1160 1170 1180 1190 1200 1210
1180 1190 1200 1210 1220 1230
pF1KE2 WGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDAHHPTPHHQQPAYPGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDAHHPTPHHQQPAYPGPK
1220 1230 1240 1250 1260 1270
1240 1250 1260 1270 1280 1290
pF1KE2 EYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEPVPRDAGKMGKTPLSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEPVPRDAGKMGKTPLSEV
1280 1290 1300 1310 1320 1330
1300 1310 1320 1330 1340 1350
pF1KE2 SQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVPDKLSSFGASCLAPSHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVPDKLSSFGASCLAPSHF
1340 1350 1360 1370 1380 1390
1360 1370 1380 1390 1400 1410
pF1KE2 TDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPSLTEKPWALGAGDFNSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPSLTEKPWALGAGDFNSA
1400 1410 1420 1430 1440 1450
1420 1430 1440 1450 1460 1470
pF1KE2 LKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSSEKLFGALKSEEKLWDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSSEKLFGALKSEEKLWDP
1460 1470 1480 1490 1500 1510
1480 1490 1500 1510 1520 1530
pF1KE2 FSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDENIGGVAVAPAHGSILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDENIGGVAVAPAHGSILI
1520 1530 1540 1550 1560 1570
1540 1550 1560 1570 1580 1590
pF1KE2 ECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALWEAKMKQLAERARARQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALWEAKMKQLAERARARQE
1580 1590 1600 1610 1620 1630
1600 1610 1620 1630 1640 1650
pF1KE2 EAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQALAVPTDSAVTVSSYAYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQALAVPTDSAVTVSSYAYT
1640 1650 1660 1670 1680 1690
1660
pF1KE2 KVTGPYSRWI
::::::::::
XP_016 KVTGPYSRWI
1700
>>XP_011530988 (OMIM: 613555) PREDICTED: methylcytosine (1776 aa)
initn: 11461 init1: 11461 opt: 11461 Z-score: 4712.6 bits: 885.1 E(85289): 0
Smith-Waterman score: 11461; 100.0% identity (100.0% similar) in 1660 aa overlap (1-1660:117-1776)
10 20 30
pF1KE2 MDSGPVYHGDSRQLSASGVPVNGAREPAGP
::::::::::::::::::::::::::::::
XP_011 RKCEVLKKKVGLLKETGSELSPVDGPVPGQMDSGPVYHGDSRQLSASGVPVNGAREPAGP
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE2 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE2 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE2 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE2 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
330 340 350 360 370 380
280 290 300 310 320 330
pF1KE2 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
390 400 410 420 430 440
340 350 360 370 380 390
pF1KE2 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
450 460 470 480 490 500
400 410 420 430 440 450
pF1KE2 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
510 520 530 540 550 560
460 470 480 490 500 510
pF1KE2 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
570 580 590 600 610 620
520 530 540 550 560 570
pF1KE2 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
630 640 650 660 670 680
580 590 600 610 620 630
pF1KE2 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
690 700 710 720 730 740
640 650 660 670 680 690
pF1KE2 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
750 760 770 780 790 800
700 710 720 730 740 750
pF1KE2 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
810 820 830 840 850 860
760 770 780 790 800 810
pF1KE2 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
870 880 890 900 910 920
820 830 840 850 860 870
pF1KE2 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
930 940 950 960 970 980
880 890 900 910 920 930
pF1KE2 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQVTNEEIAIDCRLGLKEGRPFAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQVTNEEIAIDCRLGLKEGRPFAG
990 1000 1010 1020 1030 1040
940 950 960 970 980 990
pF1KE2 VTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQLHVLPLYKMANTDEFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQLHVLPLYKMANTDEFG
1050 1060 1070 1080 1090 1100
1000 1010 1020 1030 1040 1050
pF1KE2 SEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKAAAEKKKIQKEKLSTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKAAAEKKKIQKEKLSTPE
1110 1120 1130 1140 1150 1160
1060 1070 1080 1090 1100 1110
pF1KE2 KIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSFKYSGNAVVESYSVLGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSFKYSGNAVVESYSVLGN
1170 1180 1190 1200 1210 1220
1120 1130 1140 1150 1160 1170
pF1KE2 CRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGFPSSNPVFPSQFLGPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGFPSSNPVFPSQFLGPGA
1230 1240 1250 1260 1270 1280
1180 1190 1200 1210 1220 1230
pF1KE2 WGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDAHHPTPHHQQPAYPGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDAHHPTPHHQQPAYPGPK
1290 1300 1310 1320 1330 1340
1240 1250 1260 1270 1280 1290
pF1KE2 EYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEPVPRDAGKMGKTPLSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEPVPRDAGKMGKTPLSEV
1350 1360 1370 1380 1390 1400
1300 1310 1320 1330 1340 1350
pF1KE2 SQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVPDKLSSFGASCLAPSHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVPDKLSSFGASCLAPSHF
1410 1420 1430 1440 1450 1460
1360 1370 1380 1390 1400 1410
pF1KE2 TDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPSLTEKPWALGAGDFNSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPSLTEKPWALGAGDFNSA
1470 1480 1490 1500 1510 1520
1420 1430 1440 1450 1460 1470
pF1KE2 LKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSSEKLFGALKSEEKLWDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSSEKLFGALKSEEKLWDP
1530 1540 1550 1560 1570 1580
1480 1490 1500 1510 1520 1530
pF1KE2 FSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDENIGGVAVAPAHGSILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDENIGGVAVAPAHGSILI
1590 1600 1610 1620 1630 1640
1540 1550 1560 1570 1580 1590
pF1KE2 ECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALWEAKMKQLAERARARQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALWEAKMKQLAERARARQE
1650 1660 1670 1680 1690 1700
1600 1610 1620 1630 1640 1650
pF1KE2 EAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQALAVPTDSAVTVSSYAYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQALAVPTDSAVTVSSYAYT
1710 1720 1730 1740 1750 1760
1660
pF1KE2 KVTGPYSRWI
::::::::::
XP_011 KVTGPYSRWI
1770
>>XP_005264244 (OMIM: 613555) PREDICTED: methylcytosine (1795 aa)
initn: 11461 init1: 11461 opt: 11461 Z-score: 4712.5 bits: 885.1 E(85289): 0
Smith-Waterman score: 11461; 100.0% identity (100.0% similar) in 1660 aa overlap (1-1660:136-1795)
10 20 30
pF1KE2 MDSGPVYHGDSRQLSASGVPVNGAREPAGP
::::::::::::::::::::::::::::::
XP_005 AGEGAGPWGQGAAVKTGSELSPVDGPVPGQMDSGPVYHGDSRQLSASGVPVNGAREPAGP
110 120 130 140 150 160
40 50 60 70 80 90
pF1KE2 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
170 180 190 200 210 220
100 110 120 130 140 150
pF1KE2 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
230 240 250 260 270 280
160 170 180 190 200 210
pF1KE2 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
290 300 310 320 330 340
220 230 240 250 260 270
pF1KE2 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
350 360 370 380 390 400
280 290 300 310 320 330
pF1KE2 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
410 420 430 440 450 460
340 350 360 370 380 390
pF1KE2 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
470 480 490 500 510 520
400 410 420 430 440 450
pF1KE2 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
530 540 550 560 570 580
460 470 480 490 500 510
pF1KE2 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
590 600 610 620 630 640
520 530 540 550 560 570
pF1KE2 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
650 660 670 680 690 700
580 590 600 610 620 630
pF1KE2 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
710 720 730 740 750 760
640 650 660 670 680 690
pF1KE2 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
770 780 790 800 810 820
700 710 720 730 740 750
pF1KE2 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
830 840 850 860 870 880
760 770 780 790 800 810
pF1KE2 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
890 900 910 920 930 940
820 830 840 850 860 870
pF1KE2 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
950 960 970 980 990 1000
880 890 900 910 920 930
pF1KE2 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQVTNEEIAIDCRLGLKEGRPFAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQVTNEEIAIDCRLGLKEGRPFAG
1010 1020 1030 1040 1050 1060
940 950 960 970 980 990
pF1KE2 VTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQLHVLPLYKMANTDEFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQLHVLPLYKMANTDEFG
1070 1080 1090 1100 1110 1120
1000 1010 1020 1030 1040 1050
pF1KE2 SEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKAAAEKKKIQKEKLSTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKAAAEKKKIQKEKLSTPE
1130 1140 1150 1160 1170 1180
1060 1070 1080 1090 1100 1110
pF1KE2 KIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSFKYSGNAVVESYSVLGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSFKYSGNAVVESYSVLGN
1190 1200 1210 1220 1230 1240
1120 1130 1140 1150 1160 1170
pF1KE2 CRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGFPSSNPVFPSQFLGPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGFPSSNPVFPSQFLGPGA
1250 1260 1270 1280 1290 1300
1180 1190 1200 1210 1220 1230
pF1KE2 WGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDAHHPTPHHQQPAYPGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDAHHPTPHHQQPAYPGPK
1310 1320 1330 1340 1350 1360
1240 1250 1260 1270 1280 1290
pF1KE2 EYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEPVPRDAGKMGKTPLSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEPVPRDAGKMGKTPLSEV
1370 1380 1390 1400 1410 1420
1300 1310 1320 1330 1340 1350
pF1KE2 SQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVPDKLSSFGASCLAPSHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVPDKLSSFGASCLAPSHF
1430 1440 1450 1460 1470 1480
1360 1370 1380 1390 1400 1410
pF1KE2 TDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPSLTEKPWALGAGDFNSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPSLTEKPWALGAGDFNSA
1490 1500 1510 1520 1530 1540
1420 1430 1440 1450 1460 1470
pF1KE2 LKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSSEKLFGALKSEEKLWDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSSEKLFGALKSEEKLWDP
1550 1560 1570 1580 1590 1600
1480 1490 1500 1510 1520 1530
pF1KE2 FSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDENIGGVAVAPAHGSILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDENIGGVAVAPAHGSILI
1610 1620 1630 1640 1650 1660
1540 1550 1560 1570 1580 1590
pF1KE2 ECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALWEAKMKQLAERARARQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALWEAKMKQLAERARARQE
1670 1680 1690 1700 1710 1720
1600 1610 1620 1630 1640 1650
pF1KE2 EAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQALAVPTDSAVTVSSYAYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQALAVPTDSAVTVSSYAYT
1730 1740 1750 1760 1770 1780
1660
pF1KE2 KVTGPYSRWI
::::::::::
XP_005 KVTGPYSRWI
1790
>>NP_001274420 (OMIM: 613555) methylcytosine dioxygenase (1795 aa)
initn: 11461 init1: 11461 opt: 11461 Z-score: 4712.5 bits: 885.1 E(85289): 0
Smith-Waterman score: 11461; 100.0% identity (100.0% similar) in 1660 aa overlap (1-1660:136-1795)
10 20 30
pF1KE2 MDSGPVYHGDSRQLSASGVPVNGAREPAGP
::::::::::::::::::::::::::::::
NP_001 AGEGAGPWGQGAAVKTGSELSPVDGPVPGQMDSGPVYHGDSRQLSASGVPVNGAREPAGP
110 120 130 140 150 160
40 50 60 70 80 90
pF1KE2 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
170 180 190 200 210 220
100 110 120 130 140 150
pF1KE2 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
230 240 250 260 270 280
160 170 180 190 200 210
pF1KE2 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
290 300 310 320 330 340
220 230 240 250 260 270
pF1KE2 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
350 360 370 380 390 400
280 290 300 310 320 330
pF1KE2 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
410 420 430 440 450 460
340 350 360 370 380 390
pF1KE2 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
470 480 490 500 510 520
400 410 420 430 440 450
pF1KE2 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
530 540 550 560 570 580
460 470 480 490 500 510
pF1KE2 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
590 600 610 620 630 640
520 530 540 550 560 570
pF1KE2 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
650 660 670 680 690 700
580 590 600 610 620 630
pF1KE2 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
710 720 730 740 750 760
640 650 660 670 680 690
pF1KE2 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
770 780 790 800 810 820
700 710 720 730 740 750
pF1KE2 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
830 840 850 860 870 880
760 770 780 790 800 810
pF1KE2 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
890 900 910 920 930 940
820 830 840 850 860 870
pF1KE2 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
950 960 970 980 990 1000
880 890 900 910 920 930
pF1KE2 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQVTNEEIAIDCRLGLKEGRPFAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQVTNEEIAIDCRLGLKEGRPFAG
1010 1020 1030 1040 1050 1060
940 950 960 970 980 990
pF1KE2 VTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQLHVLPLYKMANTDEFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQLHVLPLYKMANTDEFG
1070 1080 1090 1100 1110 1120
1000 1010 1020 1030 1040 1050
pF1KE2 SEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKAAAEKKKIQKEKLSTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKAAAEKKKIQKEKLSTPE
1130 1140 1150 1160 1170 1180
1060 1070 1080 1090 1100 1110
pF1KE2 KIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSFKYSGNAVVESYSVLGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSFKYSGNAVVESYSVLGN
1190 1200 1210 1220 1230 1240
1120 1130 1140 1150 1160 1170
pF1KE2 CRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGFPSSNPVFPSQFLGPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGFPSSNPVFPSQFLGPGA
1250 1260 1270 1280 1290 1300
1180 1190 1200 1210 1220 1230
pF1KE2 WGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDAHHPTPHHQQPAYPGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDAHHPTPHHQQPAYPGPK
1310 1320 1330 1340 1350 1360
1240 1250 1260 1270 1280 1290
pF1KE2 EYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEPVPRDAGKMGKTPLSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEPVPRDAGKMGKTPLSEV
1370 1380 1390 1400 1410 1420
1300 1310 1320 1330 1340 1350
pF1KE2 SQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVPDKLSSFGASCLAPSHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVPDKLSSFGASCLAPSHF
1430 1440 1450 1460 1470 1480
1360 1370 1380 1390 1400 1410
pF1KE2 TDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPSLTEKPWALGAGDFNSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPSLTEKPWALGAGDFNSA
1490 1500 1510 1520 1530 1540
1420 1430 1440 1450 1460 1470
pF1KE2 LKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSSEKLFGALKSEEKLWDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSSEKLFGALKSEEKLWDP
1550 1560 1570 1580 1590 1600
1480 1490 1500 1510 1520 1530
pF1KE2 FSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDENIGGVAVAPAHGSILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDENIGGVAVAPAHGSILI
1610 1620 1630 1640 1650 1660
1540 1550 1560 1570 1580 1590
pF1KE2 ECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALWEAKMKQLAERARARQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALWEAKMKQLAERARARQE
1670 1680 1690 1700 1710 1720
1600 1610 1620 1630 1640 1650
pF1KE2 EAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQALAVPTDSAVTVSSYAYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQALAVPTDSAVTVSSYAYT
1730 1740 1750 1760 1770 1780
1660
pF1KE2 KVTGPYSRWI
::::::::::
NP_001 KVTGPYSRWI
1790
>>XP_011530989 (OMIM: 613555) PREDICTED: methylcytosine (1718 aa)
initn: 6386 init1: 6287 opt: 6454 Z-score: 2662.5 bits: 505.7 E(85289): 1.5e-141
Smith-Waterman score: 11419; 99.0% identity (99.0% similar) in 1676 aa overlap (1-1660:43-1718)
10 20 30
pF1KE2 MDSGPVYHGDSRQLSASGVPVNGAREPAGP
::::::::::::::::::::::::::::::
XP_011 AGEGAGPWGQGAAVKTGSELSPVDGPVPGQMDSGPVYHGDSRQLSASGVPVNGAREPAGP
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE2 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE2 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE2 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE2 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE2 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE2 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE2 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
440 450 460 470 480 490
460 470 480 490 500 510
pF1KE2 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
500 510 520 530 540 550
520 530 540 550 560 570
pF1KE2 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
560 570 580 590 600 610
580 590 600 610 620 630
pF1KE2 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
620 630 640 650 660 670
640 650 660 670 680 690
pF1KE2 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
680 690 700 710 720 730
700 710 720 730 740 750
pF1KE2 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
740 750 760 770 780 790
760 770 780 790 800 810
pF1KE2 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
800 810 820 830 840 850
820 830 840 850 860 870
pF1KE2 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
860 870 880 890 900 910
880 890 900 910
pF1KE2 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQ----------------VTNEEI
:::::::::::::::::::::::::::::::::::::: ::::::
XP_011 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQLGPLSQKTSLLQSKGKVTNEEI
920 930 940 950 960 970
920 930 940 950 960 970
pF1KE2 AIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQ
980 990 1000 1010 1020 1030
980 990 1000 1010 1020 1030
pF1KE2 LHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKA
1040 1050 1060 1070 1080 1090
1040 1050 1060 1070 1080 1090
pF1KE2 AAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSF
1100 1110 1120 1130 1140 1150
1100 1110 1120 1130 1140 1150
pF1KE2 KYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGF
1160 1170 1180 1190 1200 1210
1160 1170 1180 1190 1200 1210
pF1KE2 PSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDA
1220 1230 1240 1250 1260 1270
1220 1230 1240 1250 1260 1270
pF1KE2 HHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEP
1280 1290 1300 1310 1320 1330
1280 1290 1300 1310 1320 1330
pF1KE2 VPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVP
1340 1350 1360 1370 1380 1390
1340 1350 1360 1370 1380 1390
pF1KE2 DKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPS
1400 1410 1420 1430 1440 1450
1400 1410 1420 1430 1440 1450
pF1KE2 LTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSS
1460 1470 1480 1490 1500 1510
1460 1470 1480 1490 1500 1510
pF1KE2 EKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDE
1520 1530 1540 1550 1560 1570
1520 1530 1540 1550 1560 1570
pF1KE2 NIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALW
1580 1590 1600 1610 1620 1630
1580 1590 1600 1610 1620 1630
pF1KE2 EAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQAL
1640 1650 1660 1670 1680 1690
1640 1650 1660
pF1KE2 AVPTDSAVTVSSYAYTKVTGPYSRWI
::::::::::::::::::::::::::
XP_011 AVPTDSAVTVSSYAYTKVTGPYSRWI
1700 1710
>>XP_011530987 (OMIM: 613555) PREDICTED: methylcytosine (1792 aa)
initn: 6386 init1: 6287 opt: 6454 Z-score: 2662.3 bits: 505.7 E(85289): 1.5e-141
Smith-Waterman score: 11419; 99.0% identity (99.0% similar) in 1676 aa overlap (1-1660:117-1792)
10 20 30
pF1KE2 MDSGPVYHGDSRQLSASGVPVNGAREPAGP
::::::::::::::::::::::::::::::
XP_011 RKCEVLKKKVGLLKETGSELSPVDGPVPGQMDSGPVYHGDSRQLSASGVPVNGAREPAGP
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE2 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE2 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE2 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE2 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
330 340 350 360 370 380
280 290 300 310 320 330
pF1KE2 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
390 400 410 420 430 440
340 350 360 370 380 390
pF1KE2 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
450 460 470 480 490 500
400 410 420 430 440 450
pF1KE2 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
510 520 530 540 550 560
460 470 480 490 500 510
pF1KE2 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
570 580 590 600 610 620
520 530 540 550 560 570
pF1KE2 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
630 640 650 660 670 680
580 590 600 610 620 630
pF1KE2 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
690 700 710 720 730 740
640 650 660 670 680 690
pF1KE2 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
750 760 770 780 790 800
700 710 720 730 740 750
pF1KE2 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
810 820 830 840 850 860
760 770 780 790 800 810
pF1KE2 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
870 880 890 900 910 920
820 830 840 850 860 870
pF1KE2 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
930 940 950 960 970 980
880 890 900 910
pF1KE2 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQ----------------VTNEEI
:::::::::::::::::::::::::::::::::::::: ::::::
XP_011 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQLGPLSQKTSLLQSKGKVTNEEI
990 1000 1010 1020 1030 1040
920 930 940 950 960 970
pF1KE2 AIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQ
1050 1060 1070 1080 1090 1100
980 990 1000 1010 1020 1030
pF1KE2 LHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKA
1110 1120 1130 1140 1150 1160
1040 1050 1060 1070 1080 1090
pF1KE2 AAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSF
1170 1180 1190 1200 1210 1220
1100 1110 1120 1130 1140 1150
pF1KE2 KYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGF
1230 1240 1250 1260 1270 1280
1160 1170 1180 1190 1200 1210
pF1KE2 PSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDA
1290 1300 1310 1320 1330 1340
1220 1230 1240 1250 1260 1270
pF1KE2 HHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEP
1350 1360 1370 1380 1390 1400
1280 1290 1300 1310 1320 1330
pF1KE2 VPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVP
1410 1420 1430 1440 1450 1460
1340 1350 1360 1370 1380 1390
pF1KE2 DKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPS
1470 1480 1490 1500 1510 1520
1400 1410 1420 1430 1440 1450
pF1KE2 LTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSS
1530 1540 1550 1560 1570 1580
1460 1470 1480 1490 1500 1510
pF1KE2 EKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDE
1590 1600 1610 1620 1630 1640
1520 1530 1540 1550 1560 1570
pF1KE2 NIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALW
1650 1660 1670 1680 1690 1700
1580 1590 1600 1610 1620 1630
pF1KE2 EAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQAL
1710 1720 1730 1740 1750 1760
1640 1650 1660
pF1KE2 AVPTDSAVTVSSYAYTKVTGPYSRWI
::::::::::::::::::::::::::
XP_011 AVPTDSAVTVSSYAYTKVTGPYSRWI
1770 1780 1790
>>XP_011530984 (OMIM: 613555) PREDICTED: methylcytosine (1811 aa)
initn: 6386 init1: 6287 opt: 6454 Z-score: 2662.2 bits: 505.7 E(85289): 1.5e-141
Smith-Waterman score: 11419; 99.0% identity (99.0% similar) in 1676 aa overlap (1-1660:136-1811)
10 20 30
pF1KE2 MDSGPVYHGDSRQLSASGVPVNGAREPAGP
::::::::::::::::::::::::::::::
XP_011 AGEGAGPWGQGAAVKTGSELSPVDGPVPGQMDSGPVYHGDSRQLSASGVPVNGAREPAGP
110 120 130 140 150 160
40 50 60 70 80 90
pF1KE2 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
170 180 190 200 210 220
100 110 120 130 140 150
pF1KE2 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
230 240 250 260 270 280
160 170 180 190 200 210
pF1KE2 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
290 300 310 320 330 340
220 230 240 250 260 270
pF1KE2 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
350 360 370 380 390 400
280 290 300 310 320 330
pF1KE2 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
410 420 430 440 450 460
340 350 360 370 380 390
pF1KE2 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
470 480 490 500 510 520
400 410 420 430 440 450
pF1KE2 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
530 540 550 560 570 580
460 470 480 490 500 510
pF1KE2 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
590 600 610 620 630 640
520 530 540 550 560 570
pF1KE2 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
650 660 670 680 690 700
580 590 600 610 620 630
pF1KE2 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
710 720 730 740 750 760
640 650 660 670 680 690
pF1KE2 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
770 780 790 800 810 820
700 710 720 730 740 750
pF1KE2 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
830 840 850 860 870 880
760 770 780 790 800 810
pF1KE2 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
890 900 910 920 930 940
820 830 840 850 860 870
pF1KE2 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
950 960 970 980 990 1000
880 890 900 910
pF1KE2 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQ----------------VTNEEI
:::::::::::::::::::::::::::::::::::::: ::::::
XP_011 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQLGPLSQKTSLLQSKGKVTNEEI
1010 1020 1030 1040 1050 1060
920 930 940 950 960 970
pF1KE2 AIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQ
1070 1080 1090 1100 1110 1120
980 990 1000 1010 1020 1030
pF1KE2 LHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKA
1130 1140 1150 1160 1170 1180
1040 1050 1060 1070 1080 1090
pF1KE2 AAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSF
1190 1200 1210 1220 1230 1240
1100 1110 1120 1130 1140 1150
pF1KE2 KYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGF
1250 1260 1270 1280 1290 1300
1160 1170 1180 1190 1200 1210
pF1KE2 PSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDA
1310 1320 1330 1340 1350 1360
1220 1230 1240 1250 1260 1270
pF1KE2 HHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEP
1370 1380 1390 1400 1410 1420
1280 1290 1300 1310 1320 1330
pF1KE2 VPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVP
1430 1440 1450 1460 1470 1480
1340 1350 1360 1370 1380 1390
pF1KE2 DKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPS
1490 1500 1510 1520 1530 1540
1400 1410 1420 1430 1440 1450
pF1KE2 LTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSS
1550 1560 1570 1580 1590 1600
1460 1470 1480 1490 1500 1510
pF1KE2 EKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDE
1610 1620 1630 1640 1650 1660
1520 1530 1540 1550 1560 1570
pF1KE2 NIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALW
1670 1680 1690 1700 1710 1720
1580 1590 1600 1610 1620 1630
pF1KE2 EAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQAL
1730 1740 1750 1760 1770 1780
1640 1650 1660
pF1KE2 AVPTDSAVTVSSYAYTKVTGPYSRWI
::::::::::::::::::::::::::
XP_011 AVPTDSAVTVSSYAYTKVTGPYSRWI
1790 1800 1810
>>XP_011530986 (OMIM: 613555) PREDICTED: methylcytosine (1811 aa)
initn: 6386 init1: 6287 opt: 6454 Z-score: 2662.2 bits: 505.7 E(85289): 1.5e-141
Smith-Waterman score: 11419; 99.0% identity (99.0% similar) in 1676 aa overlap (1-1660:136-1811)
10 20 30
pF1KE2 MDSGPVYHGDSRQLSASGVPVNGAREPAGP
::::::::::::::::::::::::::::::
XP_011 AGEGAGPWGQGAAVKTGSELSPVDGPVPGQMDSGPVYHGDSRQLSASGVPVNGAREPAGP
110 120 130 140 150 160
40 50 60 70 80 90
pF1KE2 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
170 180 190 200 210 220
100 110 120 130 140 150
pF1KE2 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
230 240 250 260 270 280
160 170 180 190 200 210
pF1KE2 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
290 300 310 320 330 340
220 230 240 250 260 270
pF1KE2 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
350 360 370 380 390 400
280 290 300 310 320 330
pF1KE2 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
410 420 430 440 450 460
340 350 360 370 380 390
pF1KE2 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
470 480 490 500 510 520
400 410 420 430 440 450
pF1KE2 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
530 540 550 560 570 580
460 470 480 490 500 510
pF1KE2 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
590 600 610 620 630 640
520 530 540 550 560 570
pF1KE2 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
650 660 670 680 690 700
580 590 600 610 620 630
pF1KE2 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
710 720 730 740 750 760
640 650 660 670 680 690
pF1KE2 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
770 780 790 800 810 820
700 710 720 730 740 750
pF1KE2 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
830 840 850 860 870 880
760 770 780 790 800 810
pF1KE2 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
890 900 910 920 930 940
820 830 840 850 860 870
pF1KE2 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
950 960 970 980 990 1000
880 890 900 910
pF1KE2 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQ----------------VTNEEI
:::::::::::::::::::::::::::::::::::::: ::::::
XP_011 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQLGPLSQKTSLLQSKGKVTNEEI
1010 1020 1030 1040 1050 1060
920 930 940 950 960 970
pF1KE2 AIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQ
1070 1080 1090 1100 1110 1120
980 990 1000 1010 1020 1030
pF1KE2 LHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKA
1130 1140 1150 1160 1170 1180
1040 1050 1060 1070 1080 1090
pF1KE2 AAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSF
1190 1200 1210 1220 1230 1240
1100 1110 1120 1130 1140 1150
pF1KE2 KYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGF
1250 1260 1270 1280 1290 1300
1160 1170 1180 1190 1200 1210
pF1KE2 PSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDA
1310 1320 1330 1340 1350 1360
1220 1230 1240 1250 1260 1270
pF1KE2 HHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEP
1370 1380 1390 1400 1410 1420
1280 1290 1300 1310 1320 1330
pF1KE2 VPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVP
1430 1440 1450 1460 1470 1480
1340 1350 1360 1370 1380 1390
pF1KE2 DKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPS
1490 1500 1510 1520 1530 1540
1400 1410 1420 1430 1440 1450
pF1KE2 LTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSS
1550 1560 1570 1580 1590 1600
1460 1470 1480 1490 1500 1510
pF1KE2 EKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDE
1610 1620 1630 1640 1650 1660
1520 1530 1540 1550 1560 1570
pF1KE2 NIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALW
1670 1680 1690 1700 1710 1720
1580 1590 1600 1610 1620 1630
pF1KE2 EAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQAL
1730 1740 1750 1760 1770 1780
1640 1650 1660
pF1KE2 AVPTDSAVTVSSYAYTKVTGPYSRWI
::::::::::::::::::::::::::
XP_011 AVPTDSAVTVSSYAYTKVTGPYSRWI
1790 1800 1810
>>XP_011530985 (OMIM: 613555) PREDICTED: methylcytosine (1811 aa)
initn: 6386 init1: 6287 opt: 6454 Z-score: 2662.2 bits: 505.7 E(85289): 1.5e-141
Smith-Waterman score: 11419; 99.0% identity (99.0% similar) in 1676 aa overlap (1-1660:136-1811)
10 20 30
pF1KE2 MDSGPVYHGDSRQLSASGVPVNGAREPAGP
::::::::::::::::::::::::::::::
XP_011 AGEGAGPWGQGAAVKTGSELSPVDGPVPGQMDSGPVYHGDSRQLSASGVPVNGAREPAGP
110 120 130 140 150 160
40 50 60 70 80 90
pF1KE2 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
170 180 190 200 210 220
100 110 120 130 140 150
pF1KE2 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
230 240 250 260 270 280
160 170 180 190 200 210
pF1KE2 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
290 300 310 320 330 340
220 230 240 250 260 270
pF1KE2 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
350 360 370 380 390 400
280 290 300 310 320 330
pF1KE2 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
410 420 430 440 450 460
340 350 360 370 380 390
pF1KE2 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
470 480 490 500 510 520
400 410 420 430 440 450
pF1KE2 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
530 540 550 560 570 580
460 470 480 490 500 510
pF1KE2 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
590 600 610 620 630 640
520 530 540 550 560 570
pF1KE2 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
650 660 670 680 690 700
580 590 600 610 620 630
pF1KE2 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
710 720 730 740 750 760
640 650 660 670 680 690
pF1KE2 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
770 780 790 800 810 820
700 710 720 730 740 750
pF1KE2 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
830 840 850 860 870 880
760 770 780 790 800 810
pF1KE2 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
890 900 910 920 930 940
820 830 840 850 860 870
pF1KE2 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
950 960 970 980 990 1000
880 890 900 910
pF1KE2 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQ----------------VTNEEI
:::::::::::::::::::::::::::::::::::::: ::::::
XP_011 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQLGPLSQKTSLLQSKGKVTNEEI
1010 1020 1030 1040 1050 1060
920 930 940 950 960 970
pF1KE2 AIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQ
1070 1080 1090 1100 1110 1120
980 990 1000 1010 1020 1030
pF1KE2 LHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKA
1130 1140 1150 1160 1170 1180
1040 1050 1060 1070 1080 1090
pF1KE2 AAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSF
1190 1200 1210 1220 1230 1240
1100 1110 1120 1130 1140 1150
pF1KE2 KYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGF
1250 1260 1270 1280 1290 1300
1160 1170 1180 1190 1200 1210
pF1KE2 PSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDA
1310 1320 1330 1340 1350 1360
1220 1230 1240 1250 1260 1270
pF1KE2 HHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEP
1370 1380 1390 1400 1410 1420
1280 1290 1300 1310 1320 1330
pF1KE2 VPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVP
1430 1440 1450 1460 1470 1480
1340 1350 1360 1370 1380 1390
pF1KE2 DKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPS
1490 1500 1510 1520 1530 1540
1400 1410 1420 1430 1440 1450
pF1KE2 LTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSS
1550 1560 1570 1580 1590 1600
1460 1470 1480 1490 1500 1510
pF1KE2 EKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDE
1610 1620 1630 1640 1650 1660
1520 1530 1540 1550 1560 1570
pF1KE2 NIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALW
1670 1680 1690 1700 1710 1720
1580 1590 1600 1610 1620 1630
pF1KE2 EAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQAL
1730 1740 1750 1760 1770 1780
1640 1650 1660
pF1KE2 AVPTDSAVTVSSYAYTKVTGPYSRWI
::::::::::::::::::::::::::
XP_011 AVPTDSAVTVSSYAYTKVTGPYSRWI
1790 1800 1810
>>XP_016859055 (OMIM: 613555) PREDICTED: methylcytosine (1811 aa)
initn: 6386 init1: 6287 opt: 6454 Z-score: 2662.2 bits: 505.7 E(85289): 1.5e-141
Smith-Waterman score: 11419; 99.0% identity (99.0% similar) in 1676 aa overlap (1-1660:136-1811)
10 20 30
pF1KE2 MDSGPVYHGDSRQLSASGVPVNGAREPAGP
::::::::::::::::::::::::::::::
XP_016 AGEGAGPWGQGAAVKTGSELSPVDGPVPGQMDSGPVYHGDSRQLSASGVPVNGAREPAGP
110 120 130 140 150 160
40 50 60 70 80 90
pF1KE2 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLGTGGPWRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFN
170 180 190 200 210 220
100 110 120 130 140 150
pF1KE2 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW
230 240 250 260 270 280
160 170 180 190 200 210
pF1KE2 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS
290 300 310 320 330 340
220 230 240 250 260 270
pF1KE2 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS
350 360 370 380 390 400
280 290 300 310 320 330
pF1KE2 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ
410 420 430 440 450 460
340 350 360 370 380 390
pF1KE2 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ
470 480 490 500 510 520
400 410 420 430 440 450
pF1KE2 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP
530 540 550 560 570 580
460 470 480 490 500 510
pF1KE2 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP
590 600 610 620 630 640
520 530 540 550 560 570
pF1KE2 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD
650 660 670 680 690 700
580 590 600 610 620 630
pF1KE2 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV
710 720 730 740 750 760
640 650 660 670 680 690
pF1KE2 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEF
770 780 790 800 810 820
700 710 720 730 740 750
pF1KE2 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELMEERYGEKGKAIRIEKVIYTGKEGKSS
830 840 850 860 870 880
760 770 780 790 800 810
pF1KE2 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTLYQELTD
890 900 910 920 930 940
820 830 840 850 860 870
pF1KE2 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKFR
950 960 970 980 990 1000
880 890 900 910
pF1KE2 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQ----------------VTNEEI
:::::::::::::::::::::::::::::::::::::: ::::::
XP_016 LAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAYQNQLGPLSQKTSLLQSKGKVTNEEI
1010 1020 1030 1040 1050 1060
920 930 940 950 960 970
pF1KE2 AIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGKIPEDEQ
1070 1080 1090 1100 1110 1120
980 990 1000 1010 1020 1030
pF1KE2 LHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKA
1130 1140 1150 1160 1170 1180
1040 1050 1060 1070 1080 1090
pF1KE2 AAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLKPSLKVEPQNHFSSF
1190 1200 1210 1220 1230 1240
1100 1110 1120 1130 1140 1150
pF1KE2 KYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGF
1250 1260 1270 1280 1290 1300
1160 1170 1180 1190 1200 1210
pF1KE2 PSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGAEFAELPSQAVPTDA
1310 1320 1330 1340 1350 1360
1220 1230 1240 1250 1260 1270
pF1KE2 HHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRSIKQEPVDPLTQAEP
1370 1380 1390 1400 1410 1420
1280 1290 1300 1310 1320 1330
pF1KE2 VPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGSWGVFSSGESPAIVP
1430 1440 1450 1460 1470 1480
1340 1350 1360 1370 1380 1390
pF1KE2 DKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSPCKFGNSTSALAGPS
1490 1500 1510 1520 1530 1540
1400 1410 1420 1430 1440 1450
pF1KE2 LTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQLDRAWQSFGLPLGSS
1550 1560 1570 1580 1590 1600
1460 1470 1480 1490 1500 1510
pF1KE2 EKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEEEELWSDSEHNFLDE
1610 1620 1630 1640 1650 1660
1520 1530 1540 1550 1560 1570
pF1KE2 NIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALW
1670 1680 1690 1700 1710 1720
1580 1590 1600 1610 1620 1630
pF1KE2 EAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQAL
1730 1740 1750 1760 1770 1780
1640 1650 1660
pF1KE2 AVPTDSAVTVSSYAYTKVTGPYSRWI
::::::::::::::::::::::::::
XP_016 AVPTDSAVTVSSYAYTKVTGPYSRWI
1790 1800 1810
1660 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 10:32:58 2016 done: Sun Nov 6 10:33:01 2016
Total Scan time: 19.570 Total Display time: 1.120
Function used was FASTA [36.3.4 Apr, 2011]