Result of FASTA (omim) for
pFN21AE2295
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2295, 2136 aa
1>>>pF1KE2295 2136 - 2136 aa - 2136 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4300+/-0.000479; mu= 6.0814+/- 0.030
mean_var=220.0160+/-46.135, 0's: 0 Z-trim(116.0): 63 B-trim: 1597 in 1/55
Lambda= 0.086466
statistics sampled from 26872 (26930) to 26872 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.316), width: 16
Scan time: 18.240
The best scores are: opt bits E(85289)
NP_085128 (OMIM: 607790) methylcytosine dioxygenas (2136) 14256 1793.2 0
XP_011538506 (OMIM: 607790) PREDICTED: methylcytos (2165) 10713 1351.2 0
XP_011538508 (OMIM: 607790) PREDICTED: methylcytos (1501) 9838 1242.0 0
XP_011538507 (OMIM: 607790) PREDICTED: methylcytos (1528) 6494 824.8 0
XP_016872175 (OMIM: 607790) PREDICTED: methylcytos (1516) 6398 812.9 0
XP_016872177 (OMIM: 607790) PREDICTED: methylcytos (1512) 6386 811.4 0
XP_016872176 (OMIM: 607790) PREDICTED: methylcytos (1512) 6386 811.4 0
XP_011538509 (OMIM: 607790) PREDICTED: methylcytos (1494) 6274 797.4 0
XP_016872178 (OMIM: 607790) PREDICTED: methylcytos (1494) 6274 797.4 0
XP_005263139 (OMIM: 612839,614286) PREDICTED: meth (2002) 1809 240.5 1.5e-61
NP_001120680 (OMIM: 612839,614286) methylcytosine (2002) 1809 240.5 1.5e-61
XP_016859056 (OMIM: 613555) PREDICTED: methylcytos (1702) 1727 230.2 1.5e-58
XP_011530988 (OMIM: 613555) PREDICTED: methylcytos (1776) 1727 230.2 1.6e-58
XP_005264244 (OMIM: 613555) PREDICTED: methylcytos (1795) 1727 230.2 1.6e-58
NP_001274420 (OMIM: 613555) methylcytosine dioxyge (1795) 1727 230.2 1.6e-58
XP_011530990 (OMIM: 613555) PREDICTED: methylcytos (1050) 1154 158.6 3.4e-37
XP_011530989 (OMIM: 613555) PREDICTED: methylcytos (1718) 1155 158.9 4.7e-37
XP_011530987 (OMIM: 613555) PREDICTED: methylcytos (1792) 1155 158.9 4.9e-37
XP_011530986 (OMIM: 613555) PREDICTED: methylcytos (1811) 1155 158.9 4.9e-37
XP_011530984 (OMIM: 613555) PREDICTED: methylcytos (1811) 1155 158.9 4.9e-37
XP_011530985 (OMIM: 613555) PREDICTED: methylcytos (1811) 1155 158.9 4.9e-37
XP_016859055 (OMIM: 613555) PREDICTED: methylcytos (1811) 1155 158.9 4.9e-37
XP_006714305 (OMIM: 612839,614286) PREDICTED: meth (1902) 1029 143.2 2.8e-32
XP_011530991 (OMIM: 613555) PREDICTED: methylcytos ( 953) 623 92.3 2.8e-17
XP_011530992 (OMIM: 613555) PREDICTED: methylcytos ( 953) 623 92.3 2.8e-17
XP_011530586 (OMIM: 611645) PREDICTED: CXXC-type z ( 367) 291 50.7 3.7e-05
NP_079488 (OMIM: 611645) CXXC-type zinc finger pro ( 367) 291 50.7 3.7e-05
XP_016864141 (OMIM: 611645) PREDICTED: CXXC-type z ( 367) 291 50.7 3.7e-05
NP_057547 (OMIM: 612752) CXXC-type zinc finger pro ( 322) 281 49.4 8e-05
NP_001304138 (OMIM: 612752) CXXC-type zinc finger ( 322) 281 49.4 8e-05
NP_001304133 (OMIM: 612752) CXXC-type zinc finger ( 322) 281 49.4 8e-05
NP_001304130 (OMIM: 612752) CXXC-type zinc finger ( 322) 281 49.4 8e-05
NP_001304129 (OMIM: 612752) CXXC-type zinc finger ( 322) 281 49.4 8e-05
XP_016865062 (OMIM: 612752) PREDICTED: CXXC-type z ( 322) 281 49.4 8e-05
NP_001304136 (OMIM: 612752) CXXC-type zinc finger ( 322) 281 49.4 8e-05
NP_001304137 (OMIM: 612752) CXXC-type zinc finger ( 322) 281 49.4 8e-05
NP_001304140 (OMIM: 612752) CXXC-type zinc finger ( 322) 281 49.4 8e-05
NP_001304132 (OMIM: 612752) CXXC-type zinc finger ( 322) 281 49.4 8e-05
NP_001304139 (OMIM: 612752) CXXC-type zinc finger ( 322) 281 49.4 8e-05
NP_001304128 (OMIM: 612752) CXXC-type zinc finger ( 322) 281 49.4 8e-05
NP_001304131 (OMIM: 612752) CXXC-type zinc finger ( 322) 281 49.4 8e-05
NP_001304135 (OMIM: 612752) CXXC-type zinc finger ( 322) 281 49.4 8e-05
NP_001304134 (OMIM: 612752) CXXC-type zinc finger ( 322) 281 49.4 8e-05
>>NP_085128 (OMIM: 607790) methylcytosine dioxygenase TE (2136 aa)
initn: 14256 init1: 14256 opt: 14256 Z-score: 9617.2 bits: 1793.2 E(85289): 0
Smith-Waterman score: 14256; 99.9% identity (100.0% similar) in 2136 aa overlap (1-2136:1-2136)
10 20 30 40 50 60
pF1KE2 MSRSRHARPSRLVRKEDVNKKKKNSQLRKTTKGANKNVASVKTLSPGKLKQLIQERDVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 MSRSRHARPSRLVRKEDVNKKKKNSQLRKTTKGANKNVASVKTLSPGKLKQLIQERDVKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KTEPKPPVPVRSLLTRAGAARMNLDRTEVLFQNPESLTCNGFTMALRSTSLSRRLSQPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 KTEPKPPVPVRSLLTRAGAARMNLDRTEVLFQNPESLTCNGFTMALRSTSLSRRLSQPPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VVAKSKKVPLSKGLEKQHDCDYKILPALGVKHSENDSVPMQDTQVLPDIETLIGVQNPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 VVAKSKKVPLSKGLEKQHDCDYKILPALGVKHSENDSVPMQDTQVLPDIETLIGVQNPSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LKGKSQETTQFWTQRVEDSKINIPTHSGPAAEILPGPLEGTRCGEGLFSEETLNDTSGSP
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
NP_085 LKGKSQETTQFWSQRVEDSKINIPTHSGPAAEILPGPLEGTRCGEGLFSEETLNDTSGSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KMFAQDTVCAPFPQRVTPKVTSQGNPSIQLEELGSRVESLKLSDSYLDPIKSEHDCYPTS
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_085 KMFAQDTVCAPFPQRATPKVTSQGNPSIQLEELGSRVESLKLSDSYLDPIKSEHDCYPTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SLNKVIPDLNLRNCLALGGSTSPTSVIKFLLAGSKQATLGAKPDHQEAFEATANQQEVSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 SLNKVIPDLNLRNCLALGGSTSPTSVIKFLLAGSKQATLGAKPDHQEAFEATANQQEVSD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TTSFLGQAFGAIPHQWELPGADPVHGEALGETPDLPEIPGAIPVQGEVFGTILDQQETLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 TTSFLGQAFGAIPHQWELPGADPVHGEALGETPDLPEIPGAIPVQGEVFGTILDQQETLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 MSGSVVPDLPVFLPVPPNPIATFNAPSKWPEPQSTVSYGLAVQGAIQILPLGSGHTPQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 MSGSVVPDLPVFLPVPPNPIATFNAPSKWPEPQSTVSYGLAVQGAIQILPLGSGHTPQSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SNSEKNSLPPVMAISNVENEKQVHISFLPANTQGFPLAPERGLFHASLGIAQLSQAGPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 SNSEKNSLPPVMAISNVENEKQVHISFLPANTQGFPLAPERGLFHASLGIAQLSQAGPSK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SDRGSSQVSVTSTVHVVNTTVVTMPVPMVSTSSSSYTTLLPTLEKKKRKRCGVCEPCQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 SDRGSSQVSVTSTVHVVNTTVVTMPVPMVSTSSSSYTTLLPTLEKKKRKRCGVCEPCQQK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 TNCGECTYCKNRKNSHQICKKRKCEELKKKPSVVVPLEVIKENKRPQREKKPKVLKADFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 TNCGECTYCKNRKNSHQICKKRKCEELKKKPSVVVPLEVIKENKRPQREKKPKVLKADFD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 NKPVNGPKSESMDYSRCGHGEEQKLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 NKPVNGPKSESMDYSRCGHGEEQKLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 HVKGDFSANVPEAEKSKNSEVDKKRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 HVKGDFSANVPEAEKSKNSEVDKKRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 EFGKTLENNSYKFLKDTANHKNAMSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 EFGKTLENNSYKFLKDTANHKNAMSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSH
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 SIINHHASIHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 SIINHHASIHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 SEAPSENSSPSKSEKDEESEQRTASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 SEAPSENSSPSKSEKDEESEQRTASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 KQSSCNTVVFNGQTTTLSNSHINSATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 KQSSCNTVVFNGQTTTLSNSHINSATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 IAQGIITLDNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 IAQGIITLDNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 LTQLASIIKINYIKPEDKKVESTPTSLVTCNVQQKYNQEKGTMQQKPPSSVHNNHGSSLT
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_085 LTQLASIIKINYIKPEDKKVESTPTSLVTCNVQQKYNQEKGTIQQKPPSSVHNNHGSSLT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 KQKNPTQKKTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 KQKNPTQKKTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 FCPHDFPTVFGKISSSTKIWKPLAQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 FCPHDFPTVFGKISSSTKIWKPLAQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 DSLSLFHLKTESNGKAFTDKAYNSQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 DSLSLFHLKTESNGKAFTDKAYNSQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIR
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 FQQVVKEQLMHQRLPTLPGISHETPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 FQQVVKEQLMHQRLPTLPGISHETPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSF
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 GTSEFSTVDSAQKNFNDYAMNFFTNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 GTSEFSTVDSAQKNFNDYAMNFFTNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 GAGPSVAAVREIMENRYGQKGNAIRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 GAGPSVAAVREIMENRYGQKGNAIRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLC
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 LVRQRTGHHCPTAVMVVLIMVWDGIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 LVRQRTGHHCPTAVMVVLIMVWDGIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRT
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 CTCQGIDPETCGASFSFGCSWSMYFNGCKFGRSPSPRRFRIDPSSPLHEKNLEDNLQSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 CTCQGIDPETCGASFSFGCSWSMYFNGCKFGRSPSPRRFRIDPSSPLHEKNLEDNLQSLA
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 TRLAPIYKQYAPVAYQNQVEYENVARECRLGSKEGRPFSGVTACLDFCAHPHRDIHNMNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 TRLAPIYKQYAPVAYQNQVEYENVARECRLGSKEGRPFSGVTACLDFCAHPHRDIHNMNN
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 GSTVVCTLTREDNRSLGVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKSGAIEVLAPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 GSTVVCTLTREDNRSLGVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKSGAIEVLAPR
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 RKKRTCFTQPVPRSGKKRAAMMTEVLAHKIRAVEKKPIPRIKRKNNSTTTNNSKPSSLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 RKKRTCFTQPVPRSGKKRAAMMTEVLAHKIRAVEKKPIPRIKRKNNSTTTNNSKPSSLPT
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 LGSNTETVQPEVKSETEPHFILKSSDNTKTYSLMPSAPHPVKEASPGFSWSPKTASATPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 LGSNTETVQPEVKSETEPHFILKSSDNTKTYSLMPSAPHPVKEASPGFSWSPKTASATPA
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 PLKNDATASCGFSERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLPTLSAPVMEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 PLKNDATASCGFSERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLPTLSAPVMEP
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 LINSEPSTGVTEPLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPPSDEPLSDDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 LINSEPSTGVTEPLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPPSDEPLSDDPL
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 SPAEEKLPHIDEYWSDSEHIFLDANIGGVAIAPAHGSVLIECARRELHATTPVEHPNRNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 SPAEEKLPHIDEYWSDSEHIFLDANIGGVAIAPAHGSVLIECARRELHATTPVEHPNRNH
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE2 PTRLSLVFYQHKNLNKPQHGFELNKIKFEAKEAKNKKMKASEQKDQAANEGPEQSSEVNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 PTRLSLVFYQHKNLNKPQHGFELNKIKFEAKEAKNKKMKASEQKDQAANEGPEQSSEVNE
2050 2060 2070 2080 2090 2100
2110 2120 2130
pF1KE2 LNQIPSHKALTLTHDNVVTVSPYALTHVAGPYNHWV
::::::::::::::::::::::::::::::::::::
NP_085 LNQIPSHKALTLTHDNVVTVSPYALTHVAGPYNHWV
2110 2120 2130
>>XP_011538506 (OMIM: 607790) PREDICTED: methylcytosine (2165 aa)
initn: 10755 init1: 10713 opt: 10713 Z-score: 7228.5 bits: 1351.2 E(85289): 0
Smith-Waterman score: 14188; 98.5% identity (98.7% similar) in 2165 aa overlap (1-2136:1-2165)
10 20 30 40 50 60
pF1KE2 MSRSRHARPSRLVRKEDVNKKKKNSQLRKTTKGANKNVASVKTLSPGKLKQLIQERDVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRSRHARPSRLVRKEDVNKKKKNSQLRKTTKGANKNVASVKTLSPGKLKQLIQERDVKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KTEPKPPVPVRSLLTRAGAARMNLDRTEVLFQNPESLTCNGFTMALRSTSLSRRLSQPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTEPKPPVPVRSLLTRAGAARMNLDRTEVLFQNPESLTCNGFTMALRSTSLSRRLSQPPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VVAKSKKVPLSKGLEKQHDCDYKILPALGVKHSENDSVPMQDTQVLPDIETLIGVQNPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVAKSKKVPLSKGLEKQHDCDYKILPALGVKHSENDSVPMQDTQVLPDIETLIGVQNPSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LKGKSQETTQFWTQRVEDSKINIPTHSGPAAEILPGPLEGTRCGEGLFSEETLNDTSGSP
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGKSQETTQFWSQRVEDSKINIPTHSGPAAEILPGPLEGTRCGEGLFSEETLNDTSGSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KMFAQDTVCAPFPQRVTPKVTSQGNPSIQLEELGSRVESLKLSDSYLDPIKSEHDCYPTS
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMFAQDTVCAPFPQRATPKVTSQGNPSIQLEELGSRVESLKLSDSYLDPIKSEHDCYPTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SLNKVIPDLNLRNCLALGGSTSPTSVIKFLLAGSKQATLGAKPDHQEAFEATANQQEVSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLNKVIPDLNLRNCLALGGSTSPTSVIKFLLAGSKQATLGAKPDHQEAFEATANQQEVSD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TTSFLGQAFGAIPHQWELPGADPVHGEALGETPDLPEIPGAIPVQGEVFGTILDQQETLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTSFLGQAFGAIPHQWELPGADPVHGEALGETPDLPEIPGAIPVQGEVFGTILDQQETLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 MSGSVVPDLPVFLPVPPNPIATFNAPSKWPEPQSTVSYGLAVQGAIQILPLGSGHTPQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSGSVVPDLPVFLPVPPNPIATFNAPSKWPEPQSTVSYGLAVQGAIQILPLGSGHTPQSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SNSEKNSLPPVMAISNVENEKQVHISFLPANTQGFPLAPERGLFHASLGIAQLSQAGPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNSEKNSLPPVMAISNVENEKQVHISFLPANTQGFPLAPERGLFHASLGIAQLSQAGPSK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SDRGSSQVSVTSTVHVVNTTVVTMPVPMVSTSSSSYTTLLPTLEKKKRKRCGVCEPCQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDRGSSQVSVTSTVHVVNTTVVTMPVPMVSTSSSSYTTLLPTLEKKKRKRCGVCEPCQQK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 TNCGECTYCKNRKNSHQICKKRKCEELKKKPSVVVPLEVIKENKRPQREKKPKVLKADFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNCGECTYCKNRKNSHQICKKRKCEELKKKPSVVVPLEVIKENKRPQREKKPKVLKADFD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 NKPVNGPKSESMDYSRCGHGEEQKLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKPVNGPKSESMDYSRCGHGEEQKLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 HVKGDFSANVPEAEKSKNSEVDKKRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVKGDFSANVPEAEKSKNSEVDKKRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 EFGKTLENNSYKFLKDTANHKNAMSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFGKTLENNSYKFLKDTANHKNAMSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSH
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 SIINHHASIHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIINHHASIHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 SEAPSENSSPSKSEKDEESEQRTASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAPSENSSPSKSEKDEESEQRTASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 KQSSCNTVVFNGQTTTLSNSHINSATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQSSCNTVVFNGQTTTLSNSHINSATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 IAQGIITLDNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAQGIITLDNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 LTQLASIIKINYIKPEDKKVESTPTSLVTCNVQQKYNQEKGTMQQKPPSSVHNNHGSSLT
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
XP_011 LTQLASIIKINYIKPEDKKVESTPTSLVTCNVQQKYNQEKGTIQQKPPSSVHNNHGSSLT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 KQKNPTQKKTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQKNPTQKKTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 FCPHDFPTVFGKISSSTKIWKPLAQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FCPHDFPTVFGKISSSTKIWKPLAQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 DSLSLFHLKTESNGKAFTDKAYNSQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSLSLFHLKTESNGKAFTDKAYNSQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIR
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 FQQVVKEQLMHQRLPTLPGISHETPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQQVVKEQLMHQRLPTLPGISHETPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSF
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 GTSEFSTVDSAQKNFNDYAMNFFTNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTSEFSTVDSAQKNFNDYAMNFFTNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 GAGPSVAAVREIMENRYGQKGNAIRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAGPSVAAVREIMENRYGQKGNAIRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLC
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 LVRQRTGHHCPTAVMVVLIMVWDGIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVRQRTGHHCPTAVMVVLIMVWDGIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRT
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600
pF1KE2 CTCQGIDPETCGASFSFGCSWSMYFNGCKFGRSPSPRRFRIDPSSPLH------------
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTCQGIDPETCGASFSFGCSWSMYFNGCKFGRSPSPRRFRIDPSSPLHTYYERITKGRNP
1570 1580 1590 1600 1610 1620
1610 1620 1630 1640 1650
pF1KE2 -----------------EKNLEDNLQSLATRLAPIYKQYAPVAYQNQVEYENVARECRLG
:::::::::::::::::::::::::::::::::::::::::::
XP_011 ERRYMKPERISPGHEAMEKNLEDNLQSLATRLAPIYKQYAPVAYQNQVEYENVARECRLG
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KE2 SKEGRPFSGVTACLDFCAHPHRDIHNMNNGSTVVCTLTREDNRSLGVIPQDEQLHVLPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKEGRPFSGVTACLDFCAHPHRDIHNMNNGSTVVCTLTREDNRSLGVIPQDEQLHVLPLY
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KE2 KLSDTDEFGSKEGMEAKIKSGAIEVLAPRRKKRTCFTQPVPRSGKKRAAMMTEVLAHKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLSDTDEFGSKEGMEAKIKSGAIEVLAPRRKKRTCFTQPVPRSGKKRAAMMTEVLAHKIR
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KE2 AVEKKPIPRIKRKNNSTTTNNSKPSSLPTLGSNTETVQPEVKSETEPHFILKSSDNTKTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVEKKPIPRIKRKNNSTTTNNSKPSSLPTLGSNTETVQPEVKSETEPHFILKSSDNTKTY
1810 1820 1830 1840 1850 1860
1840 1850 1860 1870 1880 1890
pF1KE2 SLMPSAPHPVKEASPGFSWSPKTASATPAPLKNDATASCGFSERSSTPHCTMPSGRLSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLMPSAPHPVKEASPGFSWSPKTASATPAPLKNDATASCGFSERSSTPHCTMPSGRLSGA
1870 1880 1890 1900 1910 1920
1900 1910 1920 1930 1940 1950
pF1KE2 NAAAADGPGISQLGEVAPLPTLSAPVMEPLINSEPSTGVTEPLTPHQPNHQPSFLTSPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAAAADGPGISQLGEVAPLPTLSAPVMEPLINSEPSTGVTEPLTPHQPNHQPSFLTSPQD
1930 1940 1950 1960 1970 1980
1960 1970 1980 1990 2000 2010
pF1KE2 LASSPMEEDEQHSEADEPPSDEPLSDDPLSPAEEKLPHIDEYWSDSEHIFLDANIGGVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LASSPMEEDEQHSEADEPPSDEPLSDDPLSPAEEKLPHIDEYWSDSEHIFLDANIGGVAI
1990 2000 2010 2020 2030 2040
2020 2030 2040 2050 2060 2070
pF1KE2 APAHGSVLIECARRELHATTPVEHPNRNHPTRLSLVFYQHKNLNKPQHGFELNKIKFEAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APAHGSVLIECARRELHATTPVEHPNRNHPTRLSLVFYQHKNLNKPQHGFELNKIKFEAK
2050 2060 2070 2080 2090 2100
2080 2090 2100 2110 2120 2130
pF1KE2 EAKNKKMKASEQKDQAANEGPEQSSEVNELNQIPSHKALTLTHDNVVTVSPYALTHVAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAKNKKMKASEQKDQAANEGPEQSSEVNELNQIPSHKALTLTHDNVVTVSPYALTHVAGP
2110 2120 2130 2140 2150 2160
pF1KE2 YNHWV
:::::
XP_011 YNHWV
>>XP_011538508 (OMIM: 607790) PREDICTED: methylcytosine (1501 aa)
initn: 9838 init1: 9838 opt: 9838 Z-score: 6640.9 bits: 1242.0 E(85289): 0
Smith-Waterman score: 9838; 99.8% identity (100.0% similar) in 1487 aa overlap (1-1487:1-1487)
10 20 30 40 50 60
pF1KE2 MSRSRHARPSRLVRKEDVNKKKKNSQLRKTTKGANKNVASVKTLSPGKLKQLIQERDVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRSRHARPSRLVRKEDVNKKKKNSQLRKTTKGANKNVASVKTLSPGKLKQLIQERDVKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KTEPKPPVPVRSLLTRAGAARMNLDRTEVLFQNPESLTCNGFTMALRSTSLSRRLSQPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTEPKPPVPVRSLLTRAGAARMNLDRTEVLFQNPESLTCNGFTMALRSTSLSRRLSQPPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VVAKSKKVPLSKGLEKQHDCDYKILPALGVKHSENDSVPMQDTQVLPDIETLIGVQNPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVAKSKKVPLSKGLEKQHDCDYKILPALGVKHSENDSVPMQDTQVLPDIETLIGVQNPSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LKGKSQETTQFWTQRVEDSKINIPTHSGPAAEILPGPLEGTRCGEGLFSEETLNDTSGSP
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGKSQETTQFWSQRVEDSKINIPTHSGPAAEILPGPLEGTRCGEGLFSEETLNDTSGSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KMFAQDTVCAPFPQRVTPKVTSQGNPSIQLEELGSRVESLKLSDSYLDPIKSEHDCYPTS
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMFAQDTVCAPFPQRATPKVTSQGNPSIQLEELGSRVESLKLSDSYLDPIKSEHDCYPTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SLNKVIPDLNLRNCLALGGSTSPTSVIKFLLAGSKQATLGAKPDHQEAFEATANQQEVSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLNKVIPDLNLRNCLALGGSTSPTSVIKFLLAGSKQATLGAKPDHQEAFEATANQQEVSD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TTSFLGQAFGAIPHQWELPGADPVHGEALGETPDLPEIPGAIPVQGEVFGTILDQQETLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTSFLGQAFGAIPHQWELPGADPVHGEALGETPDLPEIPGAIPVQGEVFGTILDQQETLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 MSGSVVPDLPVFLPVPPNPIATFNAPSKWPEPQSTVSYGLAVQGAIQILPLGSGHTPQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSGSVVPDLPVFLPVPPNPIATFNAPSKWPEPQSTVSYGLAVQGAIQILPLGSGHTPQSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SNSEKNSLPPVMAISNVENEKQVHISFLPANTQGFPLAPERGLFHASLGIAQLSQAGPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNSEKNSLPPVMAISNVENEKQVHISFLPANTQGFPLAPERGLFHASLGIAQLSQAGPSK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SDRGSSQVSVTSTVHVVNTTVVTMPVPMVSTSSSSYTTLLPTLEKKKRKRCGVCEPCQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDRGSSQVSVTSTVHVVNTTVVTMPVPMVSTSSSSYTTLLPTLEKKKRKRCGVCEPCQQK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 TNCGECTYCKNRKNSHQICKKRKCEELKKKPSVVVPLEVIKENKRPQREKKPKVLKADFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNCGECTYCKNRKNSHQICKKRKCEELKKKPSVVVPLEVIKENKRPQREKKPKVLKADFD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 NKPVNGPKSESMDYSRCGHGEEQKLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKPVNGPKSESMDYSRCGHGEEQKLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 HVKGDFSANVPEAEKSKNSEVDKKRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVKGDFSANVPEAEKSKNSEVDKKRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 EFGKTLENNSYKFLKDTANHKNAMSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFGKTLENNSYKFLKDTANHKNAMSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSH
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 SIINHHASIHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIINHHASIHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 SEAPSENSSPSKSEKDEESEQRTASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAPSENSSPSKSEKDEESEQRTASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 KQSSCNTVVFNGQTTTLSNSHINSATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQSSCNTVVFNGQTTTLSNSHINSATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 IAQGIITLDNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAQGIITLDNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 LTQLASIIKINYIKPEDKKVESTPTSLVTCNVQQKYNQEKGTMQQKPPSSVHNNHGSSLT
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
XP_011 LTQLASIIKINYIKPEDKKVESTPTSLVTCNVQQKYNQEKGTIQQKPPSSVHNNHGSSLT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 KQKNPTQKKTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQKNPTQKKTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 FCPHDFPTVFGKISSSTKIWKPLAQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FCPHDFPTVFGKISSSTKIWKPLAQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 DSLSLFHLKTESNGKAFTDKAYNSQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSLSLFHLKTESNGKAFTDKAYNSQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIR
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 FQQVVKEQLMHQRLPTLPGISHETPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQQVVKEQLMHQRLPTLPGISHETPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSF
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 GTSEFSTVDSAQKNFNDYAMNFFTNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTSEFSTVDSAQKNFNDYAMNFFTNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 GAGPSVAAVREIMENRYGQKGNAIRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLC
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAGPSVAAVREIMENRYGQKGNAIRIEIVVYTGKEGKSSHGCPIAKWGEGPKANSTQGMP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 LVRQRTGHHCPTAVMVVLIMVWDGIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRT
XP_011 W
>>XP_011538507 (OMIM: 607790) PREDICTED: methylcytosine (1528 aa)
initn: 6536 init1: 6494 opt: 6494 Z-score: 4386.4 bits: 824.8 E(85289): 0
Smith-Waterman score: 9969; 98.0% identity (98.1% similar) in 1527 aa overlap (639-2136:2-1528)
610 620 630 640 650 660
pF1KE2 CKNRKNSHQICKKRKCEELKKKPSVVVPLEVIKENKRPQREKKPKVLKADFDNKPVNGPK
::::::::::::::::::::::::::::::
XP_011 MVIKENKRPQREKKPKVLKADFDNKPVNGPK
10 20 30
670 680 690 700 710 720
pF1KE2 SESMDYSRCGHGEEQKLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTDHVKGDFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESMDYSRCGHGEEQKLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTDHVKGDFSA
40 50 60 70 80 90
730 740 750 760 770 780
pF1KE2 NVPEAEKSKNSEVDKKRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIEEFGKTLEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVPEAEKSKNSEVDKKRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIEEFGKTLEN
100 110 120 130 140 150
790 800 810 820 830 840
pF1KE2 NSYKFLKDTANHKNAMSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSHSIINHHAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSYKFLKDTANHKNAMSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSHSIINHHAS
160 170 180 190 200 210
850 860 870 880 890 900
pF1KE2 IHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQLSEAPSENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQLSEAPSENS
220 230 240 250 260 270
910 920 930 940 950 960
pF1KE2 SPSKSEKDEESEQRTASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLEKQSSCNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPSKSEKDEESEQRTASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLEKQSSCNTV
280 290 300 310 320 330
970 980 990 1000 1010 1020
pF1KE2 VFNGQTTTLSNSHINSATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKSIAQGIITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFNGQTTTLSNSHINSATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKSIAQGIITL
340 350 360 370 380 390
1030 1040 1050 1060 1070 1080
pF1KE2 DNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQLTQLASII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQLTQLASII
400 410 420 430 440 450
1090 1100 1110 1120 1130 1140
pF1KE2 KINYIKPEDKKVESTPTSLVTCNVQQKYNQEKGTMQQKPPSSVHNNHGSSLTKQKNPTQK
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_011 KINYIKPEDKKVESTPTSLVTCNVQQKYNQEKGTIQQKPPSSVHNNHGSSLTKQKNPTQK
460 470 480 490 500 510
1150 1160 1170 1180 1190 1200
pF1KE2 KTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQFCPHDFPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQFCPHDFPT
520 530 540 550 560 570
1210 1220 1230 1240 1250 1260
pF1KE2 VFGKISSSTKIWKPLAQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPLDSLSLFHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFGKISSSTKIWKPLAQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPLDSLSLFHL
580 590 600 610 620 630
1270 1280 1290 1300 1310 1320
pF1KE2 KTESNGKAFTDKAYNSQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIRFQQVVKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTESNGKAFTDKAYNSQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIRFQQVVKEQ
640 650 660 670 680 690
1330 1340 1350 1360 1370 1380
pF1KE2 LMHQRLPTLPGISHETPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSFGTSEFSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMHQRLPTLPGISHETPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSFGTSEFSTV
700 710 720 730 740 750
1390 1400 1410 1420 1430 1440
pF1KE2 DSAQKNFNDYAMNFFTNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHLGAGPSVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSAQKNFNDYAMNFFTNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHLGAGPSVAA
760 770 780 790 800 810
1450 1460 1470 1480 1490 1500
pF1KE2 VREIMENRYGQKGNAIRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLCLVRQRTGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VREIMENRYGQKGNAIRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLCLVRQRTGH
820 830 840 850 860 870
1510 1520 1530 1540 1550 1560
pF1KE2 HCPTAVMVVLIMVWDGIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRTCTCQGIDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HCPTAVMVVLIMVWDGIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRTCTCQGIDP
880 890 900 910 920 930
1570 1580 1590 1600
pF1KE2 ETCGASFSFGCSWSMYFNGCKFGRSPSPRRFRIDPSSPLH--------------------
::::::::::::::::::::::::::::::::::::::::
XP_011 ETCGASFSFGCSWSMYFNGCKFGRSPSPRRFRIDPSSPLHTYYERITKGRNPERRYMKPE
940 950 960 970 980 990
1610 1620 1630 1640 1650
pF1KE2 ---------EKNLEDNLQSLATRLAPIYKQYAPVAYQNQVEYENVARECRLGSKEGRPFS
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RISPGHEAMEKNLEDNLQSLATRLAPIYKQYAPVAYQNQVEYENVARECRLGSKEGRPFS
1000 1010 1020 1030 1040 1050
1660 1670 1680 1690 1700 1710
pF1KE2 GVTACLDFCAHPHRDIHNMNNGSTVVCTLTREDNRSLGVIPQDEQLHVLPLYKLSDTDEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVTACLDFCAHPHRDIHNMNNGSTVVCTLTREDNRSLGVIPQDEQLHVLPLYKLSDTDEF
1060 1070 1080 1090 1100 1110
1720 1730 1740 1750 1760 1770
pF1KE2 GSKEGMEAKIKSGAIEVLAPRRKKRTCFTQPVPRSGKKRAAMMTEVLAHKIRAVEKKPIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSKEGMEAKIKSGAIEVLAPRRKKRTCFTQPVPRSGKKRAAMMTEVLAHKIRAVEKKPIP
1120 1130 1140 1150 1160 1170
1780 1790 1800 1810 1820 1830
pF1KE2 RIKRKNNSTTTNNSKPSSLPTLGSNTETVQPEVKSETEPHFILKSSDNTKTYSLMPSAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIKRKNNSTTTNNSKPSSLPTLGSNTETVQPEVKSETEPHFILKSSDNTKTYSLMPSAPH
1180 1190 1200 1210 1220 1230
1840 1850 1860 1870 1880 1890
pF1KE2 PVKEASPGFSWSPKTASATPAPLKNDATASCGFSERSSTPHCTMPSGRLSGANAAAADGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVKEASPGFSWSPKTASATPAPLKNDATASCGFSERSSTPHCTMPSGRLSGANAAAADGP
1240 1250 1260 1270 1280 1290
1900 1910 1920 1930 1940 1950
pF1KE2 GISQLGEVAPLPTLSAPVMEPLINSEPSTGVTEPLTPHQPNHQPSFLTSPQDLASSPMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GISQLGEVAPLPTLSAPVMEPLINSEPSTGVTEPLTPHQPNHQPSFLTSPQDLASSPMEE
1300 1310 1320 1330 1340 1350
1960 1970 1980 1990 2000 2010
pF1KE2 DEQHSEADEPPSDEPLSDDPLSPAEEKLPHIDEYWSDSEHIFLDANIGGVAIAPAHGSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEQHSEADEPPSDEPLSDDPLSPAEEKLPHIDEYWSDSEHIFLDANIGGVAIAPAHGSVL
1360 1370 1380 1390 1400 1410
2020 2030 2040 2050 2060 2070
pF1KE2 IECARRELHATTPVEHPNRNHPTRLSLVFYQHKNLNKPQHGFELNKIKFEAKEAKNKKMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IECARRELHATTPVEHPNRNHPTRLSLVFYQHKNLNKPQHGFELNKIKFEAKEAKNKKMK
1420 1430 1440 1450 1460 1470
2080 2090 2100 2110 2120 2130
pF1KE2 ASEQKDQAANEGPEQSSEVNELNQIPSHKALTLTHDNVVTVSPYALTHVAGPYNHWV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASEQKDQAANEGPEQSSEVNELNQIPSHKALTLTHDNVVTVSPYALTHVAGPYNHWV
1480 1490 1500 1510 1520
>>XP_016872175 (OMIM: 607790) PREDICTED: methylcytosine (1516 aa)
initn: 6440 init1: 6398 opt: 6398 Z-score: 4321.7 bits: 812.9 E(85289): 0
Smith-Waterman score: 9873; 97.8% identity (98.0% similar) in 1515 aa overlap (651-2136:2-1516)
630 640 650 660 670 680
pF1KE2 KRKCEELKKKPSVVVPLEVIKENKRPQREKKPKVLKADFDNKPVNGPKSESMDYSRCGHG
.: . :::::::::::::::::::::::::
XP_016 MRPYITKADFDNKPVNGPKSESMDYSRCGHG
10 20 30
690 700 710 720 730 740
pF1KE2 EEQKLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTDHVKGDFSANVPEAEKSKNSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQKLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTDHVKGDFSANVPEAEKSKNSE
40 50 60 70 80 90
750 760 770 780 790 800
pF1KE2 VDKKRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIEEFGKTLENNSYKFLKDTANH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDKKRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIEEFGKTLENNSYKFLKDTANH
100 110 120 130 140 150
810 820 830 840 850 860
pF1KE2 KNAMSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSHSIINHHASIHNEGDQPKTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNAMSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSHSIINHHASIHNEGDQPKTPE
160 170 180 190 200 210
870 880 890 900 910 920
pF1KE2 NIPSKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQLSEAPSENSSPSKSEKDEESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIPSKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQLSEAPSENSSPSKSEKDEESE
220 230 240 250 260 270
930 940 950 960 970 980
pF1KE2 QRTASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLEKQSSCNTVVFNGQTTTLSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRTASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLEKQSSCNTVVFNGQTTTLSNS
280 290 300 310 320 330
990 1000 1010 1020 1030 1040
pF1KE2 HINSATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKSIAQGIITLDNCSNDLHQLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HINSATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKSIAQGIITLDNCSNDLHQLPP
340 350 360 370 380 390
1050 1060 1070 1080 1090 1100
pF1KE2 RNNEVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQLTQLASIIKINYIKPEDKKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNNEVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQLTQLASIIKINYIKPEDKKV
400 410 420 430 440 450
1110 1120 1130 1140 1150 1160
pF1KE2 ESTPTSLVTCNVQQKYNQEKGTMQQKPPSSVHNNHGSSLTKQKNPTQKKTKSTPSRDRRK
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 ESTPTSLVTCNVQQKYNQEKGTIQQKPPSSVHNNHGSSLTKQKNPTQKKTKSTPSRDRRK
460 470 480 490 500 510
1170 1180 1190 1200 1210 1220
pF1KE2 KKPTVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQFCPHDFPTVFGKISSSTKIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKPTVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQFCPHDFPTVFGKISSSTKIW
520 530 540 550 560 570
1230 1240 1250 1260 1270 1280
pF1KE2 KPLAQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPLDSLSLFHLKTESNGKAFTDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPLAQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPLDSLSLFHLKTESNGKAFTDK
580 590 600 610 620 630
1290 1300 1310 1320 1330 1340
pF1KE2 AYNSQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIRFQQVVKEQLMHQRLPTLPGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYNSQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIRFQQVVKEQLMHQRLPTLPGI
640 650 660 670 680 690
1350 1360 1370 1380 1390 1400
pF1KE2 SHETPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSFGTSEFSTVDSAQKNFNDYAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHETPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSFGTSEFSTVDSAQKNFNDYAM
700 710 720 730 740 750
1410 1420 1430 1440 1450 1460
pF1KE2 NFFTNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHLGAGPSVAAVREIMENRYGQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFFTNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHLGAGPSVAAVREIMENRYGQK
760 770 780 790 800 810
1470 1480 1490 1500 1510 1520
pF1KE2 GNAIRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLCLVRQRTGHHCPTAVMVVLIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNAIRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLCLVRQRTGHHCPTAVMVVLIM
820 830 840 850 860 870
1530 1540 1550 1560 1570 1580
pF1KE2 VWDGIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRTCTCQGIDPETCGASFSFGCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VWDGIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRTCTCQGIDPETCGASFSFGCS
880 890 900 910 920 930
1590 1600 1610
pF1KE2 WSMYFNGCKFGRSPSPRRFRIDPSSPLH-----------------------------EKN
:::::::::::::::::::::::::::: :::
XP_016 WSMYFNGCKFGRSPSPRRFRIDPSSPLHTYYERITKGRNPERRYMKPERISPGHEAMEKN
940 950 960 970 980 990
1620 1630 1640 1650 1660 1670
pF1KE2 LEDNLQSLATRLAPIYKQYAPVAYQNQVEYENVARECRLGSKEGRPFSGVTACLDFCAHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDNLQSLATRLAPIYKQYAPVAYQNQVEYENVARECRLGSKEGRPFSGVTACLDFCAHP
1000 1010 1020 1030 1040 1050
1680 1690 1700 1710 1720 1730
pF1KE2 HRDIHNMNNGSTVVCTLTREDNRSLGVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRDIHNMNNGSTVVCTLTREDNRSLGVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKS
1060 1070 1080 1090 1100 1110
1740 1750 1760 1770 1780 1790
pF1KE2 GAIEVLAPRRKKRTCFTQPVPRSGKKRAAMMTEVLAHKIRAVEKKPIPRIKRKNNSTTTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAIEVLAPRRKKRTCFTQPVPRSGKKRAAMMTEVLAHKIRAVEKKPIPRIKRKNNSTTTN
1120 1130 1140 1150 1160 1170
1800 1810 1820 1830 1840 1850
pF1KE2 NSKPSSLPTLGSNTETVQPEVKSETEPHFILKSSDNTKTYSLMPSAPHPVKEASPGFSWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSKPSSLPTLGSNTETVQPEVKSETEPHFILKSSDNTKTYSLMPSAPHPVKEASPGFSWS
1180 1190 1200 1210 1220 1230
1860 1870 1880 1890 1900 1910
pF1KE2 PKTASATPAPLKNDATASCGFSERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKTASATPAPLKNDATASCGFSERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLP
1240 1250 1260 1270 1280 1290
1920 1930 1940 1950 1960 1970
pF1KE2 TLSAPVMEPLINSEPSTGVTEPLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSAPVMEPLINSEPSTGVTEPLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPPS
1300 1310 1320 1330 1340 1350
1980 1990 2000 2010 2020 2030
pF1KE2 DEPLSDDPLSPAEEKLPHIDEYWSDSEHIFLDANIGGVAIAPAHGSVLIECARRELHATT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEPLSDDPLSPAEEKLPHIDEYWSDSEHIFLDANIGGVAIAPAHGSVLIECARRELHATT
1360 1370 1380 1390 1400 1410
2040 2050 2060 2070 2080 2090
pF1KE2 PVEHPNRNHPTRLSLVFYQHKNLNKPQHGFELNKIKFEAKEAKNKKMKASEQKDQAANEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVEHPNRNHPTRLSLVFYQHKNLNKPQHGFELNKIKFEAKEAKNKKMKASEQKDQAANEG
1420 1430 1440 1450 1460 1470
2100 2110 2120 2130
pF1KE2 PEQSSEVNELNQIPSHKALTLTHDNVVTVSPYALTHVAGPYNHWV
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEQSSEVNELNQIPSHKALTLTHDNVVTVSPYALTHVAGPYNHWV
1480 1490 1500 1510
>>XP_016872177 (OMIM: 607790) PREDICTED: methylcytosine (1512 aa)
initn: 6428 init1: 6386 opt: 6386 Z-score: 4313.6 bits: 811.4 E(85289): 0
Smith-Waterman score: 9861; 97.9% identity (98.1% similar) in 1512 aa overlap (654-2136:1-1512)
630 640 650 660 670 680
pF1KE2 CEELKKKPSVVVPLEVIKENKRPQREKKPKVLKADFDNKPVNGPKSESMDYSRCGHGEEQ
.:.:::::::::::::::::::::::::::
XP_016 MLQADFDNKPVNGPKSESMDYSRCGHGEEQ
10 20 30
690 700 710 720 730 740
pF1KE2 KLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTDHVKGDFSANVPEAEKSKNSEVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTDHVKGDFSANVPEAEKSKNSEVDK
40 50 60 70 80 90
750 760 770 780 790 800
pF1KE2 KRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIEEFGKTLENNSYKFLKDTANHKNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIEEFGKTLENNSYKFLKDTANHKNA
100 110 120 130 140 150
810 820 830 840 850 860
pF1KE2 MSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSHSIINHHASIHNEGDQPKTPENIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSHSIINHHASIHNEGDQPKTPENIP
160 170 180 190 200 210
870 880 890 900 910 920
pF1KE2 SKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQLSEAPSENSSPSKSEKDEESEQRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQLSEAPSENSSPSKSEKDEESEQRT
220 230 240 250 260 270
930 940 950 960 970 980
pF1KE2 ASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLEKQSSCNTVVFNGQTTTLSNSHIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLEKQSSCNTVVFNGQTTTLSNSHIN
280 290 300 310 320 330
990 1000 1010 1020 1030 1040
pF1KE2 SATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKSIAQGIITLDNCSNDLHQLPPRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKSIAQGIITLDNCSNDLHQLPPRNN
340 350 360 370 380 390
1050 1060 1070 1080 1090 1100
pF1KE2 EVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQLTQLASIIKINYIKPEDKKVEST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQLTQLASIIKINYIKPEDKKVEST
400 410 420 430 440 450
1110 1120 1130 1140 1150 1160
pF1KE2 PTSLVTCNVQQKYNQEKGTMQQKPPSSVHNNHGSSLTKQKNPTQKKTKSTPSRDRRKKKP
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 PTSLVTCNVQQKYNQEKGTIQQKPPSSVHNNHGSSLTKQKNPTQKKTKSTPSRDRRKKKP
460 470 480 490 500 510
1170 1180 1190 1200 1210 1220
pF1KE2 TVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQFCPHDFPTVFGKISSSTKIWKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQFCPHDFPTVFGKISSSTKIWKPL
520 530 540 550 560 570
1230 1240 1250 1260 1270 1280
pF1KE2 AQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPLDSLSLFHLKTESNGKAFTDKAYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPLDSLSLFHLKTESNGKAFTDKAYN
580 590 600 610 620 630
1290 1300 1310 1320 1330 1340
pF1KE2 SQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIRFQQVVKEQLMHQRLPTLPGISHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIRFQQVVKEQLMHQRLPTLPGISHE
640 650 660 670 680 690
1350 1360 1370 1380 1390 1400
pF1KE2 TPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSFGTSEFSTVDSAQKNFNDYAMNFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSFGTSEFSTVDSAQKNFNDYAMNFF
700 710 720 730 740 750
1410 1420 1430 1440 1450 1460
pF1KE2 TNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHLGAGPSVAAVREIMENRYGQKGNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHLGAGPSVAAVREIMENRYGQKGNA
760 770 780 790 800 810
1470 1480 1490 1500 1510 1520
pF1KE2 IRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLCLVRQRTGHHCPTAVMVVLIMVWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLCLVRQRTGHHCPTAVMVVLIMVWD
820 830 840 850 860 870
1530 1540 1550 1560 1570 1580
pF1KE2 GIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRTCTCQGIDPETCGASFSFGCSWSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRTCTCQGIDPETCGASFSFGCSWSM
880 890 900 910 920 930
1590 1600 1610
pF1KE2 YFNGCKFGRSPSPRRFRIDPSSPLH-----------------------------EKNLED
::::::::::::::::::::::::: ::::::
XP_016 YFNGCKFGRSPSPRRFRIDPSSPLHTYYERITKGRNPERRYMKPERISPGHEAMEKNLED
940 950 960 970 980 990
1620 1630 1640 1650 1660 1670
pF1KE2 NLQSLATRLAPIYKQYAPVAYQNQVEYENVARECRLGSKEGRPFSGVTACLDFCAHPHRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLQSLATRLAPIYKQYAPVAYQNQVEYENVARECRLGSKEGRPFSGVTACLDFCAHPHRD
1000 1010 1020 1030 1040 1050
1680 1690 1700 1710 1720 1730
pF1KE2 IHNMNNGSTVVCTLTREDNRSLGVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKSGAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHNMNNGSTVVCTLTREDNRSLGVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKSGAI
1060 1070 1080 1090 1100 1110
1740 1750 1760 1770 1780 1790
pF1KE2 EVLAPRRKKRTCFTQPVPRSGKKRAAMMTEVLAHKIRAVEKKPIPRIKRKNNSTTTNNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVLAPRRKKRTCFTQPVPRSGKKRAAMMTEVLAHKIRAVEKKPIPRIKRKNNSTTTNNSK
1120 1130 1140 1150 1160 1170
1800 1810 1820 1830 1840 1850
pF1KE2 PSSLPTLGSNTETVQPEVKSETEPHFILKSSDNTKTYSLMPSAPHPVKEASPGFSWSPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSSLPTLGSNTETVQPEVKSETEPHFILKSSDNTKTYSLMPSAPHPVKEASPGFSWSPKT
1180 1190 1200 1210 1220 1230
1860 1870 1880 1890 1900 1910
pF1KE2 ASATPAPLKNDATASCGFSERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLPTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASATPAPLKNDATASCGFSERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLPTLS
1240 1250 1260 1270 1280 1290
1920 1930 1940 1950 1960 1970
pF1KE2 APVMEPLINSEPSTGVTEPLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPPSDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APVMEPLINSEPSTGVTEPLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPPSDEP
1300 1310 1320 1330 1340 1350
1980 1990 2000 2010 2020 2030
pF1KE2 LSDDPLSPAEEKLPHIDEYWSDSEHIFLDANIGGVAIAPAHGSVLIECARRELHATTPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSDDPLSPAEEKLPHIDEYWSDSEHIFLDANIGGVAIAPAHGSVLIECARRELHATTPVE
1360 1370 1380 1390 1400 1410
2040 2050 2060 2070 2080 2090
pF1KE2 HPNRNHPTRLSLVFYQHKNLNKPQHGFELNKIKFEAKEAKNKKMKASEQKDQAANEGPEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPNRNHPTRLSLVFYQHKNLNKPQHGFELNKIKFEAKEAKNKKMKASEQKDQAANEGPEQ
1420 1430 1440 1450 1460 1470
2100 2110 2120 2130
pF1KE2 SSEVNELNQIPSHKALTLTHDNVVTVSPYALTHVAGPYNHWV
::::::::::::::::::::::::::::::::::::::::::
XP_016 SSEVNELNQIPSHKALTLTHDNVVTVSPYALTHVAGPYNHWV
1480 1490 1500 1510
>>XP_016872176 (OMIM: 607790) PREDICTED: methylcytosine (1512 aa)
initn: 6428 init1: 6386 opt: 6386 Z-score: 4313.6 bits: 811.4 E(85289): 0
Smith-Waterman score: 9861; 97.9% identity (98.1% similar) in 1512 aa overlap (654-2136:1-1512)
630 640 650 660 670 680
pF1KE2 CEELKKKPSVVVPLEVIKENKRPQREKKPKVLKADFDNKPVNGPKSESMDYSRCGHGEEQ
.:.:::::::::::::::::::::::::::
XP_016 MLQADFDNKPVNGPKSESMDYSRCGHGEEQ
10 20 30
690 700 710 720 730 740
pF1KE2 KLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTDHVKGDFSANVPEAEKSKNSEVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTDHVKGDFSANVPEAEKSKNSEVDK
40 50 60 70 80 90
750 760 770 780 790 800
pF1KE2 KRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIEEFGKTLENNSYKFLKDTANHKNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIEEFGKTLENNSYKFLKDTANHKNA
100 110 120 130 140 150
810 820 830 840 850 860
pF1KE2 MSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSHSIINHHASIHNEGDQPKTPENIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSHSIINHHASIHNEGDQPKTPENIP
160 170 180 190 200 210
870 880 890 900 910 920
pF1KE2 SKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQLSEAPSENSSPSKSEKDEESEQRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQLSEAPSENSSPSKSEKDEESEQRT
220 230 240 250 260 270
930 940 950 960 970 980
pF1KE2 ASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLEKQSSCNTVVFNGQTTTLSNSHIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLEKQSSCNTVVFNGQTTTLSNSHIN
280 290 300 310 320 330
990 1000 1010 1020 1030 1040
pF1KE2 SATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKSIAQGIITLDNCSNDLHQLPPRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKSIAQGIITLDNCSNDLHQLPPRNN
340 350 360 370 380 390
1050 1060 1070 1080 1090 1100
pF1KE2 EVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQLTQLASIIKINYIKPEDKKVEST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQLTQLASIIKINYIKPEDKKVEST
400 410 420 430 440 450
1110 1120 1130 1140 1150 1160
pF1KE2 PTSLVTCNVQQKYNQEKGTMQQKPPSSVHNNHGSSLTKQKNPTQKKTKSTPSRDRRKKKP
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 PTSLVTCNVQQKYNQEKGTIQQKPPSSVHNNHGSSLTKQKNPTQKKTKSTPSRDRRKKKP
460 470 480 490 500 510
1170 1180 1190 1200 1210 1220
pF1KE2 TVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQFCPHDFPTVFGKISSSTKIWKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQFCPHDFPTVFGKISSSTKIWKPL
520 530 540 550 560 570
1230 1240 1250 1260 1270 1280
pF1KE2 AQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPLDSLSLFHLKTESNGKAFTDKAYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPLDSLSLFHLKTESNGKAFTDKAYN
580 590 600 610 620 630
1290 1300 1310 1320 1330 1340
pF1KE2 SQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIRFQQVVKEQLMHQRLPTLPGISHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIRFQQVVKEQLMHQRLPTLPGISHE
640 650 660 670 680 690
1350 1360 1370 1380 1390 1400
pF1KE2 TPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSFGTSEFSTVDSAQKNFNDYAMNFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSFGTSEFSTVDSAQKNFNDYAMNFF
700 710 720 730 740 750
1410 1420 1430 1440 1450 1460
pF1KE2 TNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHLGAGPSVAAVREIMENRYGQKGNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHLGAGPSVAAVREIMENRYGQKGNA
760 770 780 790 800 810
1470 1480 1490 1500 1510 1520
pF1KE2 IRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLCLVRQRTGHHCPTAVMVVLIMVWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLCLVRQRTGHHCPTAVMVVLIMVWD
820 830 840 850 860 870
1530 1540 1550 1560 1570 1580
pF1KE2 GIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRTCTCQGIDPETCGASFSFGCSWSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRTCTCQGIDPETCGASFSFGCSWSM
880 890 900 910 920 930
1590 1600 1610
pF1KE2 YFNGCKFGRSPSPRRFRIDPSSPLH-----------------------------EKNLED
::::::::::::::::::::::::: ::::::
XP_016 YFNGCKFGRSPSPRRFRIDPSSPLHTYYERITKGRNPERRYMKPERISPGHEAMEKNLED
940 950 960 970 980 990
1620 1630 1640 1650 1660 1670
pF1KE2 NLQSLATRLAPIYKQYAPVAYQNQVEYENVARECRLGSKEGRPFSGVTACLDFCAHPHRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLQSLATRLAPIYKQYAPVAYQNQVEYENVARECRLGSKEGRPFSGVTACLDFCAHPHRD
1000 1010 1020 1030 1040 1050
1680 1690 1700 1710 1720 1730
pF1KE2 IHNMNNGSTVVCTLTREDNRSLGVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKSGAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHNMNNGSTVVCTLTREDNRSLGVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKSGAI
1060 1070 1080 1090 1100 1110
1740 1750 1760 1770 1780 1790
pF1KE2 EVLAPRRKKRTCFTQPVPRSGKKRAAMMTEVLAHKIRAVEKKPIPRIKRKNNSTTTNNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVLAPRRKKRTCFTQPVPRSGKKRAAMMTEVLAHKIRAVEKKPIPRIKRKNNSTTTNNSK
1120 1130 1140 1150 1160 1170
1800 1810 1820 1830 1840 1850
pF1KE2 PSSLPTLGSNTETVQPEVKSETEPHFILKSSDNTKTYSLMPSAPHPVKEASPGFSWSPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSSLPTLGSNTETVQPEVKSETEPHFILKSSDNTKTYSLMPSAPHPVKEASPGFSWSPKT
1180 1190 1200 1210 1220 1230
1860 1870 1880 1890 1900 1910
pF1KE2 ASATPAPLKNDATASCGFSERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLPTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASATPAPLKNDATASCGFSERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLPTLS
1240 1250 1260 1270 1280 1290
1920 1930 1940 1950 1960 1970
pF1KE2 APVMEPLINSEPSTGVTEPLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPPSDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APVMEPLINSEPSTGVTEPLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPPSDEP
1300 1310 1320 1330 1340 1350
1980 1990 2000 2010 2020 2030
pF1KE2 LSDDPLSPAEEKLPHIDEYWSDSEHIFLDANIGGVAIAPAHGSVLIECARRELHATTPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSDDPLSPAEEKLPHIDEYWSDSEHIFLDANIGGVAIAPAHGSVLIECARRELHATTPVE
1360 1370 1380 1390 1400 1410
2040 2050 2060 2070 2080 2090
pF1KE2 HPNRNHPTRLSLVFYQHKNLNKPQHGFELNKIKFEAKEAKNKKMKASEQKDQAANEGPEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPNRNHPTRLSLVFYQHKNLNKPQHGFELNKIKFEAKEAKNKKMKASEQKDQAANEGPEQ
1420 1430 1440 1450 1460 1470
2100 2110 2120 2130
pF1KE2 SSEVNELNQIPSHKALTLTHDNVVTVSPYALTHVAGPYNHWV
::::::::::::::::::::::::::::::::::::::::::
XP_016 SSEVNELNQIPSHKALTLTHDNVVTVSPYALTHVAGPYNHWV
1480 1490 1500 1510
>>XP_011538509 (OMIM: 607790) PREDICTED: methylcytosine (1494 aa)
initn: 6316 init1: 6274 opt: 6274 Z-score: 4238.2 bits: 797.4 E(85289): 0
Smith-Waterman score: 9749; 98.0% identity (98.1% similar) in 1494 aa overlap (672-2136:1-1494)
650 660 670 680 690 700
pF1KE2 ENKRPQREKKPKVLKADFDNKPVNGPKSESMDYSRCGHGEEQKLELNPHTVENVTKNEDS
::::::::::::::::::::::::::::::
XP_011 MDYSRCGHGEEQKLELNPHTVENVTKNEDS
10 20 30
710 720 730 740 750 760
pF1KE2 MTGIEVEKWTQNKKSQLTDHVKGDFSANVPEAEKSKNSEVDKKRTKSPKLFVQTVRNGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTGIEVEKWTQNKKSQLTDHVKGDFSANVPEAEKSKNSEVDKKRTKSPKLFVQTVRNGIK
40 50 60 70 80 90
770 780 790 800 810 820
pF1KE2 HVHCLPAETNVSFKKFNIEEFGKTLENNSYKFLKDTANHKNAMSSVATDMSCDHLKGRSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVHCLPAETNVSFKKFNIEEFGKTLENNSYKFLKDTANHKNAMSSVATDMSCDHLKGRSN
100 110 120 130 140 150
830 840 850 860 870 880
pF1KE2 VLVFQQPGFNCSSIPHSSHSIINHHASIHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLVFQQPGFNCSSIPHSSHSIINHHASIHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLM
160 170 180 190 200 210
890 900 910 920 930 940
pF1KE2 KDRRLTLEQVVAIEALTQLSEAPSENSSPSKSEKDEESEQRTASLLNSCKAILYTVRKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDRRLTLEQVVAIEALTQLSEAPSENSSPSKSEKDEESEQRTASLLNSCKAILYTVRKDL
220 230 240 250 260 270
950 960 970 980 990 1000
pF1KE2 QDPNLQGEPPKLNHCPSLEKQSSCNTVVFNGQTTTLSNSHINSATNQASTKSHEYSKVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDPNLQGEPPKLNHCPSLEKQSSCNTVVFNGQTTTLSNSHINSATNQASTKSHEYSKVTN
280 290 300 310 320 330
1010 1020 1030 1040 1050 1060
pF1KE2 SLSLFIPKSNSSKIDTNKSIAQGIITLDNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSLFIPKSNSSKIDTNKSIAQGIITLDNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSD
340 350 360 370 380 390
1070 1080 1090 1100 1110 1120
pF1KE2 DLSCQDATHTQIEEDVATQLTQLASIIKINYIKPEDKKVESTPTSLVTCNVQQKYNQEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSCQDATHTQIEEDVATQLTQLASIIKINYIKPEDKKVESTPTSLVTCNVQQKYNQEKG
400 410 420 430 440 450
1130 1140 1150 1160 1170 1180
pF1KE2 TMQQKPPSSVHNNHGSSLTKQKNPTQKKTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSY
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIQQKPPSSVHNNHGSSLTKQKNPTQKKTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSY
460 470 480 490 500 510
1190 1200 1210 1220 1230 1240
pF1KE2 MYGTICDIWIASKFQNFGQFCPHDFPTVFGKISSSTKIWKPLAQTRSIMQPKTVFPPLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYGTICDIWIASKFQNFGQFCPHDFPTVFGKISSSTKIWKPLAQTRSIMQPKTVFPPLTQ
520 530 540 550 560 570
1250 1260 1270 1280 1290 1300
pF1KE2 IKLQRYPESAEEKVKVEPLDSLSLFHLKTESNGKAFTDKAYNSQVQLTVNANQKAHPLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKLQRYPESAEEKVKVEPLDSLSLFHLKTESNGKAFTDKAYNSQVQLTVNANQKAHPLTQ
580 590 600 610 620 630
1310 1320 1330 1340 1350 1360
pF1KE2 PSSPPNQCANVMAGDDQIRFQQVVKEQLMHQRLPTLPGISHETPLPESALTLRNVNVVCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSPPNQCANVMAGDDQIRFQQVVKEQLMHQRLPTLPGISHETPLPESALTLRNVNVVCS
640 650 660 670 680 690
1370 1380 1390 1400 1410 1420
pF1KE2 GGITVVSTKSEEEVCSSSFGTSEFSTVDSAQKNFNDYAMNFFTNPTKNLVSITKDSELPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGITVVSTKSEEEVCSSSFGTSEFSTVDSAQKNFNDYAMNFFTNPTKNLVSITKDSELPT
700 710 720 730 740 750
1430 1440 1450 1460 1470 1480
pF1KE2 CSCLDRVIQKDKGPYYTHLGAGPSVAAVREIMENRYGQKGNAIRIEIVVYTGKEGKSSHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSCLDRVIQKDKGPYYTHLGAGPSVAAVREIMENRYGQKGNAIRIEIVVYTGKEGKSSHG
760 770 780 790 800 810
1490 1500 1510 1520 1530 1540
pF1KE2 CPIAKWVLRRSSDEEKVLCLVRQRTGHHCPTAVMVVLIMVWDGIPLPMADRLYTELTENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPIAKWVLRRSSDEEKVLCLVRQRTGHHCPTAVMVVLIMVWDGIPLPMADRLYTELTENL
820 830 840 850 860 870
1550 1560 1570 1580 1590 1600
pF1KE2 KSYNGHPTDRRCTLNENRTCTCQGIDPETCGASFSFGCSWSMYFNGCKFGRSPSPRRFRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSYNGHPTDRRCTLNENRTCTCQGIDPETCGASFSFGCSWSMYFNGCKFGRSPSPRRFRI
880 890 900 910 920 930
1610 1620 1630
pF1KE2 DPSSPLH-----------------------------EKNLEDNLQSLATRLAPIYKQYAP
::::::: ::::::::::::::::::::::::
XP_011 DPSSPLHTYYERITKGRNPERRYMKPERISPGHEAMEKNLEDNLQSLATRLAPIYKQYAP
940 950 960 970 980 990
1640 1650 1660 1670 1680 1690
pF1KE2 VAYQNQVEYENVARECRLGSKEGRPFSGVTACLDFCAHPHRDIHNMNNGSTVVCTLTRED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAYQNQVEYENVARECRLGSKEGRPFSGVTACLDFCAHPHRDIHNMNNGSTVVCTLTRED
1000 1010 1020 1030 1040 1050
1700 1710 1720 1730 1740 1750
pF1KE2 NRSLGVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKSGAIEVLAPRRKKRTCFTQPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRSLGVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKSGAIEVLAPRRKKRTCFTQPVP
1060 1070 1080 1090 1100 1110
1760 1770 1780 1790 1800 1810
pF1KE2 RSGKKRAAMMTEVLAHKIRAVEKKPIPRIKRKNNSTTTNNSKPSSLPTLGSNTETVQPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSGKKRAAMMTEVLAHKIRAVEKKPIPRIKRKNNSTTTNNSKPSSLPTLGSNTETVQPEV
1120 1130 1140 1150 1160 1170
1820 1830 1840 1850 1860 1870
pF1KE2 KSETEPHFILKSSDNTKTYSLMPSAPHPVKEASPGFSWSPKTASATPAPLKNDATASCGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSETEPHFILKSSDNTKTYSLMPSAPHPVKEASPGFSWSPKTASATPAPLKNDATASCGF
1180 1190 1200 1210 1220 1230
1880 1890 1900 1910 1920 1930
pF1KE2 SERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLPTLSAPVMEPLINSEPSTGVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLPTLSAPVMEPLINSEPSTGVTE
1240 1250 1260 1270 1280 1290
1940 1950 1960 1970 1980 1990
pF1KE2 PLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPPSDEPLSDDPLSPAEEKLPHIDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPPSDEPLSDDPLSPAEEKLPHIDE
1300 1310 1320 1330 1340 1350
2000 2010 2020 2030 2040 2050
pF1KE2 YWSDSEHIFLDANIGGVAIAPAHGSVLIECARRELHATTPVEHPNRNHPTRLSLVFYQHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YWSDSEHIFLDANIGGVAIAPAHGSVLIECARRELHATTPVEHPNRNHPTRLSLVFYQHK
1360 1370 1380 1390 1400 1410
2060 2070 2080 2090 2100 2110
pF1KE2 NLNKPQHGFELNKIKFEAKEAKNKKMKASEQKDQAANEGPEQSSEVNELNQIPSHKALTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLNKPQHGFELNKIKFEAKEAKNKKMKASEQKDQAANEGPEQSSEVNELNQIPSHKALTL
1420 1430 1440 1450 1460 1470
2120 2130
pF1KE2 THDNVVTVSPYALTHVAGPYNHWV
::::::::::::::::::::::::
XP_011 THDNVVTVSPYALTHVAGPYNHWV
1480 1490
>>XP_016872178 (OMIM: 607790) PREDICTED: methylcytosine (1494 aa)
initn: 6316 init1: 6274 opt: 6274 Z-score: 4238.2 bits: 797.4 E(85289): 0
Smith-Waterman score: 9749; 98.0% identity (98.1% similar) in 1494 aa overlap (672-2136:1-1494)
650 660 670 680 690 700
pF1KE2 ENKRPQREKKPKVLKADFDNKPVNGPKSESMDYSRCGHGEEQKLELNPHTVENVTKNEDS
::::::::::::::::::::::::::::::
XP_016 MDYSRCGHGEEQKLELNPHTVENVTKNEDS
10 20 30
710 720 730 740 750 760
pF1KE2 MTGIEVEKWTQNKKSQLTDHVKGDFSANVPEAEKSKNSEVDKKRTKSPKLFVQTVRNGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTGIEVEKWTQNKKSQLTDHVKGDFSANVPEAEKSKNSEVDKKRTKSPKLFVQTVRNGIK
40 50 60 70 80 90
770 780 790 800 810 820
pF1KE2 HVHCLPAETNVSFKKFNIEEFGKTLENNSYKFLKDTANHKNAMSSVATDMSCDHLKGRSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVHCLPAETNVSFKKFNIEEFGKTLENNSYKFLKDTANHKNAMSSVATDMSCDHLKGRSN
100 110 120 130 140 150
830 840 850 860 870 880
pF1KE2 VLVFQQPGFNCSSIPHSSHSIINHHASIHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLVFQQPGFNCSSIPHSSHSIINHHASIHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLM
160 170 180 190 200 210
890 900 910 920 930 940
pF1KE2 KDRRLTLEQVVAIEALTQLSEAPSENSSPSKSEKDEESEQRTASLLNSCKAILYTVRKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDRRLTLEQVVAIEALTQLSEAPSENSSPSKSEKDEESEQRTASLLNSCKAILYTVRKDL
220 230 240 250 260 270
950 960 970 980 990 1000
pF1KE2 QDPNLQGEPPKLNHCPSLEKQSSCNTVVFNGQTTTLSNSHINSATNQASTKSHEYSKVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDPNLQGEPPKLNHCPSLEKQSSCNTVVFNGQTTTLSNSHINSATNQASTKSHEYSKVTN
280 290 300 310 320 330
1010 1020 1030 1040 1050 1060
pF1KE2 SLSLFIPKSNSSKIDTNKSIAQGIITLDNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSLFIPKSNSSKIDTNKSIAQGIITLDNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSD
340 350 360 370 380 390
1070 1080 1090 1100 1110 1120
pF1KE2 DLSCQDATHTQIEEDVATQLTQLASIIKINYIKPEDKKVESTPTSLVTCNVQQKYNQEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLSCQDATHTQIEEDVATQLTQLASIIKINYIKPEDKKVESTPTSLVTCNVQQKYNQEKG
400 410 420 430 440 450
1130 1140 1150 1160 1170 1180
pF1KE2 TMQQKPPSSVHNNHGSSLTKQKNPTQKKTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSY
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIQQKPPSSVHNNHGSSLTKQKNPTQKKTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSY
460 470 480 490 500 510
1190 1200 1210 1220 1230 1240
pF1KE2 MYGTICDIWIASKFQNFGQFCPHDFPTVFGKISSSTKIWKPLAQTRSIMQPKTVFPPLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYGTICDIWIASKFQNFGQFCPHDFPTVFGKISSSTKIWKPLAQTRSIMQPKTVFPPLTQ
520 530 540 550 560 570
1250 1260 1270 1280 1290 1300
pF1KE2 IKLQRYPESAEEKVKVEPLDSLSLFHLKTESNGKAFTDKAYNSQVQLTVNANQKAHPLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKLQRYPESAEEKVKVEPLDSLSLFHLKTESNGKAFTDKAYNSQVQLTVNANQKAHPLTQ
580 590 600 610 620 630
1310 1320 1330 1340 1350 1360
pF1KE2 PSSPPNQCANVMAGDDQIRFQQVVKEQLMHQRLPTLPGISHETPLPESALTLRNVNVVCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSSPPNQCANVMAGDDQIRFQQVVKEQLMHQRLPTLPGISHETPLPESALTLRNVNVVCS
640 650 660 670 680 690
1370 1380 1390 1400 1410 1420
pF1KE2 GGITVVSTKSEEEVCSSSFGTSEFSTVDSAQKNFNDYAMNFFTNPTKNLVSITKDSELPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGITVVSTKSEEEVCSSSFGTSEFSTVDSAQKNFNDYAMNFFTNPTKNLVSITKDSELPT
700 710 720 730 740 750
1430 1440 1450 1460 1470 1480
pF1KE2 CSCLDRVIQKDKGPYYTHLGAGPSVAAVREIMENRYGQKGNAIRIEIVVYTGKEGKSSHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSCLDRVIQKDKGPYYTHLGAGPSVAAVREIMENRYGQKGNAIRIEIVVYTGKEGKSSHG
760 770 780 790 800 810
1490 1500 1510 1520 1530 1540
pF1KE2 CPIAKWVLRRSSDEEKVLCLVRQRTGHHCPTAVMVVLIMVWDGIPLPMADRLYTELTENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPIAKWVLRRSSDEEKVLCLVRQRTGHHCPTAVMVVLIMVWDGIPLPMADRLYTELTENL
820 830 840 850 860 870
1550 1560 1570 1580 1590 1600
pF1KE2 KSYNGHPTDRRCTLNENRTCTCQGIDPETCGASFSFGCSWSMYFNGCKFGRSPSPRRFRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSYNGHPTDRRCTLNENRTCTCQGIDPETCGASFSFGCSWSMYFNGCKFGRSPSPRRFRI
880 890 900 910 920 930
1610 1620 1630
pF1KE2 DPSSPLH-----------------------------EKNLEDNLQSLATRLAPIYKQYAP
::::::: ::::::::::::::::::::::::
XP_016 DPSSPLHTYYERITKGRNPERRYMKPERISPGHEAMEKNLEDNLQSLATRLAPIYKQYAP
940 950 960 970 980 990
1640 1650 1660 1670 1680 1690
pF1KE2 VAYQNQVEYENVARECRLGSKEGRPFSGVTACLDFCAHPHRDIHNMNNGSTVVCTLTRED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAYQNQVEYENVARECRLGSKEGRPFSGVTACLDFCAHPHRDIHNMNNGSTVVCTLTRED
1000 1010 1020 1030 1040 1050
1700 1710 1720 1730 1740 1750
pF1KE2 NRSLGVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKSGAIEVLAPRRKKRTCFTQPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRSLGVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKSGAIEVLAPRRKKRTCFTQPVP
1060 1070 1080 1090 1100 1110
1760 1770 1780 1790 1800 1810
pF1KE2 RSGKKRAAMMTEVLAHKIRAVEKKPIPRIKRKNNSTTTNNSKPSSLPTLGSNTETVQPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSGKKRAAMMTEVLAHKIRAVEKKPIPRIKRKNNSTTTNNSKPSSLPTLGSNTETVQPEV
1120 1130 1140 1150 1160 1170
1820 1830 1840 1850 1860 1870
pF1KE2 KSETEPHFILKSSDNTKTYSLMPSAPHPVKEASPGFSWSPKTASATPAPLKNDATASCGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSETEPHFILKSSDNTKTYSLMPSAPHPVKEASPGFSWSPKTASATPAPLKNDATASCGF
1180 1190 1200 1210 1220 1230
1880 1890 1900 1910 1920 1930
pF1KE2 SERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLPTLSAPVMEPLINSEPSTGVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLPTLSAPVMEPLINSEPSTGVTE
1240 1250 1260 1270 1280 1290
1940 1950 1960 1970 1980 1990
pF1KE2 PLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPPSDEPLSDDPLSPAEEKLPHIDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPPSDEPLSDDPLSPAEEKLPHIDE
1300 1310 1320 1330 1340 1350
2000 2010 2020 2030 2040 2050
pF1KE2 YWSDSEHIFLDANIGGVAIAPAHGSVLIECARRELHATTPVEHPNRNHPTRLSLVFYQHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YWSDSEHIFLDANIGGVAIAPAHGSVLIECARRELHATTPVEHPNRNHPTRLSLVFYQHK
1360 1370 1380 1390 1400 1410
2060 2070 2080 2090 2100 2110
pF1KE2 NLNKPQHGFELNKIKFEAKEAKNKKMKASEQKDQAANEGPEQSSEVNELNQIPSHKALTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLNKPQHGFELNKIKFEAKEAKNKKMKASEQKDQAANEGPEQSSEVNELNQIPSHKALTL
1420 1430 1440 1450 1460 1470
2120 2130
pF1KE2 THDNVVTVSPYALTHVAGPYNHWV
::::::::::::::::::::::::
XP_016 THDNVVTVSPYALTHVAGPYNHWV
1480 1490
>>XP_005263139 (OMIM: 612839,614286) PREDICTED: methylcy (2002 aa)
initn: 2130 init1: 999 opt: 1809 Z-score: 1226.1 bits: 240.5 E(85289): 1.5e-61
Smith-Waterman score: 1859; 35.1% identity (62.6% similar) in 1070 aa overlap (941-1970:653-1674)
920 930 940 950 960 970
pF1KE2 SKSEKDEESEQRTASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLEKQSSCNTVVF
.: :. : . : .: :. . :: :.:
XP_005 KTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFH
630 640 650 660 670 680
980 990 1000 1010
pF1KE2 -----NGQTTTLSN----SHINSATNQAS--TKSHEYSKVTNSLSLFIPKSNSSKIDTNK
..:: : . .:.:. .... ..:: .. .. . :.::.. :.
XP_005 FQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQ
690 700 710 720 730 740
1020 1030 1040 1050 1060 1070
pF1KE2 SIAQGIITLDNCSNDLHQLP-PR-NNEVEYCNQLLDSSKKLDSDDLSCQDATHTQIE-ED
. : . . : . :. .: :. ::. . .... ..: . : . ...: ..
XP_005 QQQQKL-QIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQYSKSSEFETHN
750 760 770 780 790 800
1080 1090 1100 1110 1120 1130
pF1KE2 VATQLTQLASIIKINYIKPEDKKVESTPTSL-VTCNVQQKYNQEKGTMQQKPPSSVHNNH
: : .. .: . : .: .. ..:. .. :.:. . . .:. . .: . :.
XP_005 VQMGLEEVQNINRRN--SPYSQTMKSSACKIQVSCSNNTHLVSENKEQTTHPELFAGNKT
810 820 830 840 850
1140 1150 1160 1170 1180 1190
pF1KE2 GSSLTKQKNPTQKKTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSYMYGTICDIWIASKF
. : :.. :..: .. .::.. :: .. : . : :
XP_005 QNLHHMQYFPNN----VIPKQDLLHR-----CFQEQE-QKSQQASVLQGYKNRNQDMSGQ
860 870 880 890 900
1200 1210 1220 1230 1240 1250
pF1KE2 Q--NFGQ--FCPHDFPTVFGKISSSTKIWKPLAQTRSIMQPKTV-FPPLTQIKLQRYPES
: ...: . :. .:: ... ..:.. : : : ::. ..
XP_005 QAAQLAQQRYLIHNHANVFPVPDQGG------SHTQTPPQKDTQKHAALRWHLLQKQEQQ
910 920 930 940 950 960
1260 1270 1280 1290 1300 1310
pF1KE2 AEEKVKVEPLDSLSLFHLKTESNGKAFTDKAYNSQVQLTVNANQKAHPLTQPSSPPNQCA
.. ..: : .:.: . : .. .. . :. . .:. .:: .:
XP_005 QTQQPQTESCHSQMHRPIKVEPGCKP------HACMHTAPPENKTWKKVTKQENPPASCD
970 980 990 1000 1010
1320 1330 1340 1350 1360
pF1KE2 NVMAGDDQIRFQQVVKEQLMHQRLPTLPGISHETPLPESALTLRN---VNVVCSGGITVV
:: :: . :.:.: . . : . ..::::.. :.: :: .::.
XP_005 NV---------QQKSIIETMEQHLKQFHAKSL---FDHKALTLKSQKQVKVEMSGPVTVL
1020 1030 1040 1050 1060
1370 1380 1390 1400 1410
pF1KE2 STKSE-----------EEVCSSSFGTSEFSTVDSAQKNFNDYAMNFFTNPTKNLVS--IT
. .. :. .:: : :. :. .:: . ... .: :::.. .
XP_005 TRQTTAAELDSHTPALEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVK
1070 1080 1090 1100 1110 1120
1420 1430 1440 1450 1460 1470
pF1KE2 KDSELPTCSCLDRVIQKDKGPYYTHLGAGPSVAAVREIMENRYGQKGNAIRIEIVVYTGK
. ..:.: :....:.::.::.::::::::.:::.:::::.:.::::.::::: :.::::
XP_005 TQYDFPSCRCVEQIIEKDEGPFYTHLGAGPNVAAIREIMEERFGQKGKAIRIERVIYTGK
1130 1140 1150 1160 1170 1180
1480 1490 1500 1510 1520 1530
pF1KE2 EGKSSHGCPIAKWVLRRSSDEEKVLCLVRQRTGHHCPTAVMVVLIMVWDGIPLPMADRLY
:::::.::::::::.::::.:::.:::::.:.:: : .::.:.::.::.:::: .::.::
XP_005 EGKSSQGCPIAKWVVRRSSSEEKLLCLVRERAGHTCEAAVIVILILVWEGIPLSLADKLY
1190 1200 1210 1220 1230 1240
1540 1550 1560 1570 1580 1590
pF1KE2 TELTENLKSYNGHPTDRRCTLNENRTCTCQGIDPETCGASFSFGCSWSMYFNGCKFGRSP
.::::.:..: : :.:::.:::.:::.:::.::::::::::::::::::.:::::.::
XP_005 SELTETLRKY-GTLTNRRCALNEERTCACQGLDPETCGASFSFGCSWSMYYNGCKFARSK
1250 1260 1270 1280 1290 1300
1600 1610 1620 1630 1640 1650
pF1KE2 SPRRFRIDPSSPLHEKNLEDNLQSLATRLAPIYKQYAPVAYQNQVEYENVARECRLGSKE
::.:.. ..: .:..::..::.:.: .:: ::. :: ::.::.:::. : ::::: ::
XP_005 IPRKFKLLGDDPKEEEKLESHLQNLSTLMAPTYKKLAPDAYNNQIEYEHRAPECRLGLKE
1310 1320 1330 1340 1350 1360
1660 1670 1680 1690 1700 1710
pF1KE2 GRPFSGVTACLDFCAHPHRDIHNMNNGSTVVCTLTREDNRSLGVIPQDEQLHVLPLYKLS
:::::::::::::::: :::.:::.::::.:::::::::: .: :.:::::::::::.:
XP_005 GRPFSGVTACLDFCAHAHRDLHNMQNGSTLVCTLTREDNREFGGKPEDEQLHVLPLYKVS
1370 1380 1390 1400 1410 1420
1720 1730 1740 1750 1760 1770
pF1KE2 DTDEFGSKEGMEAKIKSGAIEVLAPRRKKRTCFTQPVPRSGKKRAAMMTEVLAHKIRAVE
:.::::: :..: : .::::.::. :.: ...:: .. ..: .. :.:. ..:
XP_005 DVDEFGSVEAQEEKKRSGAIQVLSSFRRKVRMLAEPV-KTCRQRKLEAKKAAAEKLSSLE
1430 1440 1450 1460 1470 1480
1780 1790 1800 1810 1820 1830
pF1KE2 KKPIPRIKRKNNSTTTNNSKPSSLPT-LGSNTETVQPEVKSETEPHFILKSSDNTKTYSL
.. :.:. . :.... .: :. . : ... .:. . :. . . .
XP_005 NSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQR
1490 1500 1510 1520 1530 1540
1840 1850 1860 1870 1880 1890
pF1KE2 -MPSAPH-PVKEASPGFSWSPKTASATPAPLKNDATASCGFSERSSTPHCTMPSGRLSGA
. . :: : :. ..: : .: : : .. . :. :. : : . : .
XP_005 PQQQQPHHPQTESVNSYSASGSTNPYMRRP--NPVSPYPNSSHTSDIYGSTSPMNFYSTS
1550 1560 1570 1580 1590 1600
1900 1910 1920 1930 1940 1950
pF1KE2 NAAAADGPGISQLGEVAPLP-TLSAPVMEPLINSEPSTGVTEPLTPHQPNHQPSFLTSPQ
. :: : ... . . : : :. .. : . . . .: . .:. ...:. ..:.
XP_005 SQAA--GSYLNSSNPMNPYPGLLNQNTQYPSYQCNGNLSV-DNCSPYLGSYSPQ--SQPM
1610 1620 1630 1640 1650
1960 1970 1980 1990 2000 2010
pF1KE2 DLASSPMEEDEQHSEADEPPSDEPLSDDPLSPAEEKLPHIDEYWSDSEHIFLDANIGGVA
:: : .. :. . ::
XP_005 DLYRYPSQDPL--SKLSLPPIHTLYQPRFGNSQSFTSKYLGYGNQNMQGDGFSSCTIRPN
1660 1670 1680 1690 1700 1710
>--
initn: 528 init1: 414 opt: 510 Z-score: 350.4 bits: 78.4 E(85289): 8.9e-13
Smith-Waterman score: 510; 50.0% identity (78.1% similar) in 160 aa overlap (1991-2136:1844-2002)
1970 1980 1990 2000 2010 2020
pF1KE2 EQHSEADEPPSDEPLSDDPLSPAEEKLPHIDEYWSDSEHIFLDANIGGVAIAPAHGSVLI
:: :::::. ::: .:::::.::.:::.::
XP_005 GGLHKLSDANGQEKQPLALVQGVASGAEDNDEVWSDSEQSFLDPDIGGVAVAPTHGSILI
1820 1830 1840 1850 1860 1870
2030 2040 2050 2060 2070
pF1KE2 ECARRELHATTPVEHPNRNHPTRLSLVFYQHKNLNKPQHGFELNKIKFEAKEAKNKK---
:::.::::::::...::::::::.::::::::..:.:.::. : . :. :..:..:.
XP_005 ECAKRELHATTPLKNPNRNHPTRISLVFYQHKSMNEPKHGLALWEAKM-AEKAREKEEEC
1880 1890 1900 1910 1920 1930
2080 2090 2100 2110 2120
pF1KE2 ---------MKASEQKDQAANEGPEQSSEVNELNQIPS--HKALTLTHDNVVTVSPYALT
.:. .: . :...:: . : : : ......: :..::.::::.:
XP_005 EKYGPDYVPQKSHGKKVKREPAEPHETSEPTYLRFIKSLAERTMSVTTDSTVTTSPYAFT
1940 1950 1960 1970 1980 1990
2130
pF1KE2 HVAGPYNHWV
.:.::::...
XP_005 RVTGPYNRYI
2000
2136 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:27:16 2016 done: Sun Nov 6 15:27:18 2016
Total Scan time: 18.240 Total Display time: 1.120
Function used was FASTA [36.3.4 Apr, 2011]