Result of FASTA (omim) for
pFN21AE2280
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2280, 406 aa
1>>>pF1KE2280 406 - 406 aa - 406 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9410+/-0.000327; mu= 13.9505+/- 0.020
mean_var=84.0840+/-16.675, 0's: 0 Z-trim(117.4): 83 B-trim: 267 in 1/54
Lambda= 0.139868
statistics sampled from 29319 (29404) to 29319 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.345), width: 16
Scan time: 8.890
The best scores are: opt bits E(85289)
NP_064575 (OMIM: 610088) olfactomedin-like protein ( 406) 2761 566.8 3.3e-161
XP_016857337 (OMIM: 610088) PREDICTED: olfactomedi ( 386) 2504 514.9 1.3e-145
NP_001273281 (OMIM: 610088) olfactomedin-like prot ( 386) 2504 514.9 1.3e-145
NP_001273282 (OMIM: 610088) olfactomedin-like prot ( 345) 2349 483.6 3.1e-136
NP_001269541 (OMIM: 605366) noelin isoform 5 [Homo ( 458) 354 81.1 5.9e-15
NP_055094 (OMIM: 605366) noelin isoform 1 precurso ( 467) 354 81.2 6e-15
NP_001269540 (OMIM: 605366) noelin isoform 4 precu ( 485) 354 81.2 6.2e-15
NP_000252 (OMIM: 137750,601652) myocilin precursor ( 504) 346 79.6 2e-14
NP_001269644 (OMIM: 615899) olfactomedin-like prot ( 438) 344 79.1 2.3e-14
XP_005251817 (OMIM: 615899) PREDICTED: olfactomedi ( 569) 344 79.2 2.9e-14
XP_006717052 (OMIM: 615899) PREDICTED: olfactomedi ( 616) 344 79.2 3.1e-14
NP_872293 (OMIM: 615899) olfactomedin-like protein ( 652) 344 79.2 3.2e-14
XP_016881970 (OMIM: 616416) PREDICTED: adhesion G ( 878) 315 73.4 2.4e-12
NP_001284635 (OMIM: 607018) adhesion G protein-cou (1123) 316 73.7 2.5e-12
XP_016856287 (OMIM: 607018) PREDICTED: adhesion G (1163) 316 73.7 2.6e-12
XP_016856286 (OMIM: 607018) PREDICTED: adhesion G (1173) 316 73.7 2.6e-12
NP_001284634 (OMIM: 607018) adhesion G protein-cou (1177) 316 73.7 2.6e-12
XP_016856284 (OMIM: 607018) PREDICTED: adhesion G (1181) 316 73.7 2.6e-12
XP_016856285 (OMIM: 607018) PREDICTED: adhesion G (1186) 316 73.7 2.7e-12
XP_016856283 (OMIM: 607018) PREDICTED: adhesion G (1191) 316 73.7 2.7e-12
XP_016856282 (OMIM: 607018) PREDICTED: adhesion G (1225) 316 73.7 2.7e-12
NP_036434 (OMIM: 607018) adhesion G protein-couple (1403) 316 73.8 3.1e-12
NP_001284633 (OMIM: 607018) adhesion G protein-cou (1403) 316 73.8 3.1e-12
XP_016856281 (OMIM: 607018) PREDICTED: adhesion G (1408) 316 73.8 3.1e-12
NP_001317574 (OMIM: 607018) adhesion G protein-cou (1416) 316 73.8 3.1e-12
XP_016856279 (OMIM: 607018) PREDICTED: adhesion G (1421) 316 73.8 3.1e-12
XP_016856278 (OMIM: 607018) PREDICTED: adhesion G (1446) 316 73.8 3.1e-12
XP_005270725 (OMIM: 607018) PREDICTED: adhesion G (1446) 316 73.8 3.1e-12
XP_016856277 (OMIM: 607018) PREDICTED: adhesion G (1451) 316 73.8 3.1e-12
XP_016856276 (OMIM: 607018) PREDICTED: adhesion G (1459) 316 73.8 3.2e-12
XP_005270723 (OMIM: 607018) PREDICTED: adhesion G (1459) 316 73.8 3.2e-12
XP_016856275 (OMIM: 607018) PREDICTED: adhesion G (1463) 316 73.8 3.2e-12
XP_016856274 (OMIM: 607018) PREDICTED: adhesion G (1463) 316 73.8 3.2e-12
XP_016856273 (OMIM: 607018) PREDICTED: adhesion G (1464) 316 73.8 3.2e-12
XP_016856271 (OMIM: 607018) PREDICTED: adhesion G (1464) 316 73.8 3.2e-12
XP_016856272 (OMIM: 607018) PREDICTED: adhesion G (1464) 316 73.8 3.2e-12
XP_006710552 (OMIM: 607018) PREDICTED: adhesion G (1464) 316 73.8 3.2e-12
XP_006710548 (OMIM: 607018) PREDICTED: adhesion G (1464) 316 73.8 3.2e-12
XP_006710551 (OMIM: 607018) PREDICTED: adhesion G (1464) 316 73.8 3.2e-12
XP_016881969 (OMIM: 616416) PREDICTED: adhesion G (1420) 315 73.6 3.6e-12
XP_011526103 (OMIM: 616416) PREDICTED: adhesion G (1425) 315 73.6 3.6e-12
NP_055736 (OMIM: 616416) adhesion G protein-couple (1469) 315 73.6 3.7e-12
NP_001275752 (OMIM: 607567) noelin-3 isoform 3 [Ho ( 383) 307 71.6 3.7e-12
XP_016855729 (OMIM: 607567) PREDICTED: noelin-3 is ( 383) 307 71.6 3.7e-12
NP_001008701 (OMIM: 616416) adhesion G protein-cou (1474) 315 73.6 3.7e-12
XP_016881968 (OMIM: 616416) PREDICTED: adhesion G (1476) 315 73.6 3.7e-12
XP_016881967 (OMIM: 616416) PREDICTED: adhesion G (1482) 315 73.6 3.7e-12
XP_005259875 (OMIM: 616416) PREDICTED: adhesion G (1493) 315 73.6 3.7e-12
XP_016881966 (OMIM: 616416) PREDICTED: adhesion G (1499) 315 73.6 3.7e-12
XP_011526100 (OMIM: 616416) PREDICTED: adhesion G (1500) 315 73.6 3.7e-12
>>NP_064575 (OMIM: 610088) olfactomedin-like protein 3 i (406 aa)
initn: 2761 init1: 2761 opt: 2761 Z-score: 3015.2 bits: 566.8 E(85289): 3.3e-161
Smith-Waterman score: 2761; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406)
10 20 30 40 50 60
pF1KE2 MGPSTPLLILFLLSWSGPLQGQQHHLVEYMERRLAALEERLAQCQDQSSRHAAELRDFKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MGPSTPLLILFLLSWSGPLQGQQHHLVEYMERRLAALEERLAQCQDQSSRHAAELRDFKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KMLPLLEVAEKEREALRTEADTISGRVDRLEREVDYLETQNPALPCVEFDEKVTGGPGTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 KMLPLLEVAEKEREALRTEADTISGRVDRLEREVDYLETQNPALPCVEFDEKVTGGPGTK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GKGRRNEKYDMVTDCGYTISQVRSMKILKRFGGPAGLWTKDPLGQTEKIYVLDGTQNDTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 GKGRRNEKYDMVTDCGYTISQVRSMKILKRFGGPAGLWTKDPLGQTEKIYVLDGTQNDTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 FVFPRLRDFTLAMAARKASRVRVPFPWVGTGQLVYGGFLYFARRPPGRPGGGGEMENTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 FVFPRLRDFTLAMAARKASRVRVPFPWVGTGQLVYGGFLYFARRPPGRPGGGGEMENTLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LIKFHLANRTVVDSSVFPAEGLIPPYGLTADTYIDLAADEEGLWAVYATREDDRHLCLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 LIKFHLANRTVVDSSVFPAEGLIPPYGLTADTYIDLAADEEGLWAVYATREDDRHLCLAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 LDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERA
310 320 330 340 350 360
370 380 390 400
pF1KE2 ALPYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV
::::::::::::::::::::::::::::::::::::::::::::::
NP_064 ALPYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV
370 380 390 400
>>XP_016857337 (OMIM: 610088) PREDICTED: olfactomedin-li (386 aa)
initn: 2504 init1: 2504 opt: 2504 Z-score: 2735.2 bits: 514.9 E(85289): 1.3e-145
Smith-Waterman score: 2504; 100.0% identity (100.0% similar) in 368 aa overlap (39-406:19-386)
10 20 30 40 50 60
pF1KE2 ILFLLSWSGPLQGQQHHLVEYMERRLAALEERLAQCQDQSSRHAAELRDFKNKMLPLLEV
::::::::::::::::::::::::::::::
XP_016 MAQWHCSQRTQAGGHGVGERLAQCQDQSSRHAAELRDFKNKMLPLLEV
10 20 30 40
70 80 90 100 110 120
pF1KE2 AEKEREALRTEADTISGRVDRLEREVDYLETQNPALPCVEFDEKVTGGPGTKGKGRRNEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEKEREALRTEADTISGRVDRLEREVDYLETQNPALPCVEFDEKVTGGPGTKGKGRRNEK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 YDMVTDCGYTISQVRSMKILKRFGGPAGLWTKDPLGQTEKIYVLDGTQNDTAFVFPRLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDMVTDCGYTISQVRSMKILKRFGGPAGLWTKDPLGQTEKIYVLDGTQNDTAFVFPRLRD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 FTLAMAARKASRVRVPFPWVGTGQLVYGGFLYFARRPPGRPGGGGEMENTLQLIKFHLAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTLAMAARKASRVRVPFPWVGTGQLVYGGFLYFARRPPGRPGGGGEMENTLQLIKFHLAN
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE2 RTVVDSSVFPAEGLIPPYGLTADTYIDLAADEEGLWAVYATREDDRHLCLAKLDPQTLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTVVDSSVFPAEGLIPPYGLTADTYIDLAADEEGLWAVYATREDDRHLCLAKLDPQTLDT
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE2 EQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERAALPYFPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERAALPYFPRR
290 300 310 320 330 340
370 380 390 400
pF1KE2 YGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV
::::::::::::::::::::::::::::::::::::::
XP_016 YGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV
350 360 370 380
>>NP_001273281 (OMIM: 610088) olfactomedin-like protein (386 aa)
initn: 2504 init1: 2504 opt: 2504 Z-score: 2735.2 bits: 514.9 E(85289): 1.3e-145
Smith-Waterman score: 2504; 100.0% identity (100.0% similar) in 368 aa overlap (39-406:19-386)
10 20 30 40 50 60
pF1KE2 ILFLLSWSGPLQGQQHHLVEYMERRLAALEERLAQCQDQSSRHAAELRDFKNKMLPLLEV
::::::::::::::::::::::::::::::
NP_001 MAQWHCSQRTQAGGHGVGERLAQCQDQSSRHAAELRDFKNKMLPLLEV
10 20 30 40
70 80 90 100 110 120
pF1KE2 AEKEREALRTEADTISGRVDRLEREVDYLETQNPALPCVEFDEKVTGGPGTKGKGRRNEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEKEREALRTEADTISGRVDRLEREVDYLETQNPALPCVEFDEKVTGGPGTKGKGRRNEK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 YDMVTDCGYTISQVRSMKILKRFGGPAGLWTKDPLGQTEKIYVLDGTQNDTAFVFPRLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDMVTDCGYTISQVRSMKILKRFGGPAGLWTKDPLGQTEKIYVLDGTQNDTAFVFPRLRD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 FTLAMAARKASRVRVPFPWVGTGQLVYGGFLYFARRPPGRPGGGGEMENTLQLIKFHLAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTLAMAARKASRVRVPFPWVGTGQLVYGGFLYFARRPPGRPGGGGEMENTLQLIKFHLAN
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE2 RTVVDSSVFPAEGLIPPYGLTADTYIDLAADEEGLWAVYATREDDRHLCLAKLDPQTLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTVVDSSVFPAEGLIPPYGLTADTYIDLAADEEGLWAVYATREDDRHLCLAKLDPQTLDT
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE2 EQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERAALPYFPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERAALPYFPRR
290 300 310 320 330 340
370 380 390 400
pF1KE2 YGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV
::::::::::::::::::::::::::::::::::::::
NP_001 YGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV
350 360 370 380
>>NP_001273282 (OMIM: 610088) olfactomedin-like protein (345 aa)
initn: 2349 init1: 2349 opt: 2349 Z-score: 2566.9 bits: 483.6 E(85289): 3.1e-136
Smith-Waterman score: 2349; 100.0% identity (100.0% similar) in 345 aa overlap (62-406:1-345)
40 50 60 70 80 90
pF1KE2 RRLAALEERLAQCQDQSSRHAAELRDFKNKMLPLLEVAEKEREALRTEADTISGRVDRLE
::::::::::::::::::::::::::::::
NP_001 MLPLLEVAEKEREALRTEADTISGRVDRLE
10 20 30
100 110 120 130 140 150
pF1KE2 REVDYLETQNPALPCVEFDEKVTGGPGTKGKGRRNEKYDMVTDCGYTISQVRSMKILKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REVDYLETQNPALPCVEFDEKVTGGPGTKGKGRRNEKYDMVTDCGYTISQVRSMKILKRF
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE2 GGPAGLWTKDPLGQTEKIYVLDGTQNDTAFVFPRLRDFTLAMAARKASRVRVPFPWVGTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGPAGLWTKDPLGQTEKIYVLDGTQNDTAFVFPRLRDFTLAMAARKASRVRVPFPWVGTG
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE2 QLVYGGFLYFARRPPGRPGGGGEMENTLQLIKFHLANRTVVDSSVFPAEGLIPPYGLTAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLVYGGFLYFARRPPGRPGGGGEMENTLQLIKFHLANRTVVDSSVFPAEGLIPPYGLTAD
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE2 TYIDLAADEEGLWAVYATREDDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYIDLAADEEGLWAVYATREDDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTL
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE2 YVVYNTRPASRARIQCSFDASGTLTPERAALPYFPRRYGAHASLRYNPRERQLYAWDDGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVVYNTRPASRARIQCSFDASGTLTPERAALPYFPRRYGAHASLRYNPRERQLYAWDDGY
280 290 300 310 320 330
400
pF1KE2 QIVYKLEMRKKEEEV
:::::::::::::::
NP_001 QIVYKLEMRKKEEEV
340
>>NP_001269541 (OMIM: 605366) noelin isoform 5 [Homo sap (458 aa)
initn: 487 init1: 228 opt: 354 Z-score: 389.4 bits: 81.1 E(85289): 5.9e-15
Smith-Waterman score: 520; 28.5% identity (57.4% similar) in 383 aa overlap (27-399:95-449)
10 20 30 40 50
pF1KE2 MGPSTPLLILFLLSWSGPLQGQQHHLVEYMERRLAALEERLAQCQDQSSRHAA-EL
:: :: .. .:: .. : ... ..: : ..
NP_001 KQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQF
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE2 RDFKNKM---LPLLEVAEKEREALRTEADTISGRVDRLEREVDYLETQNPALPCVEFDEK
. .: :: ::. : :. ...: . .... .. :. . . ..::
NP_001 KAIKAKMDELRPLIPVLEE----YKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDEL
130 140 150 160 170 180
120 130 140 150 160 170
pF1KE2 VTGGPGTKGKGRRNEKYDMVTDCGYTISQVRSMKILKRFGGPAGLWTKDPLGQT--EKIY
. . . . : . :: .. . . .: :. : : :::. ....
NP_001 QSRVSNLEERLRACMQK---LACG-KLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVW
190 200 210 220 230
180 190 200 210 220
pF1KE2 VLDGTQNDTAFV--FPRLRDFTLAMAARKASRVRVPFPWVGTGQLVYGGFLYFARRPPGR
.:: .:. :: . . :: : . . . :.: :: ::::.::.: .:: .
NP_001 YMDGYHNNR-FVREYKSMVDF---MNTDNFTSHRLPHPWSGTGQVVYNGSIYFNK-----
240 250 260 270 280
230 240 250 260 270 280
pF1KE2 PGGGGEMENTLQLIKFHLANRTVVDSSVFPAEGL--IPPYGLTADTYIDLAADEEGLWAV
.. .:.: : ..:.. . . : . :. . . ::: .:: :::::
NP_001 -------FQSHIIIRFDLKTETILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDESGLWAV
290 300 310 320 330 340
290 300 310 320 330 340
pF1KE2 YATREDDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQ
::: .. .. ...::: .:.: : :.: :...: ::.:::::::. . .....
NP_001 YATNQNAGNIVVSRLDPVSLQTLQTWNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYA
350 360 370 380 390 400
350 360 370 380 390 400
pF1KE2 CSFDASGTLTPERAALPYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV
. .:: : : .: : .:. . : :::..: ::::..:.::.:.. .
NP_001 YQTNAS---TYEYIDIP-FQNKYSHISMLDYNPKDRALYAWNNGHQILYNVTLFHVIRSD
410 420 430 440 450
NP_001 EL
>>NP_055094 (OMIM: 605366) noelin isoform 1 precursor [H (467 aa)
initn: 487 init1: 228 opt: 354 Z-score: 389.3 bits: 81.2 E(85289): 6e-15
Smith-Waterman score: 520; 28.5% identity (57.4% similar) in 383 aa overlap (27-399:104-458)
10 20 30 40 50
pF1KE2 MGPSTPLLILFLLSWSGPLQGQQHHLVEYMERRLAALEERLAQCQDQSSRHAA-EL
:: :: .. .:: .. : ... ..: : ..
NP_055 KQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQF
80 90 100 110 120 130
60 70 80 90 100 110
pF1KE2 RDFKNKM---LPLLEVAEKEREALRTEADTISGRVDRLEREVDYLETQNPALPCVEFDEK
. .: :: ::. : :. ...: . .... .. :. . . ..::
NP_055 KAIKAKMDELRPLIPVLEE----YKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDEL
140 150 160 170 180
120 130 140 150 160 170
pF1KE2 VTGGPGTKGKGRRNEKYDMVTDCGYTISQVRSMKILKRFGGPAGLWTKDPLGQT--EKIY
. . . . : . :: .. . . .: :. : : :::. ....
NP_055 QSRVSNLEERLRACMQK---LACG-KLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVW
190 200 210 220 230 240
180 190 200 210 220
pF1KE2 VLDGTQNDTAFV--FPRLRDFTLAMAARKASRVRVPFPWVGTGQLVYGGFLYFARRPPGR
.:: .:. :: . . :: : . . . :.: :: ::::.::.: .:: .
NP_055 YMDGYHNNR-FVREYKSMVDF---MNTDNFTSHRLPHPWSGTGQVVYNGSIYFNK-----
250 260 270 280 290
230 240 250 260 270 280
pF1KE2 PGGGGEMENTLQLIKFHLANRTVVDSSVFPAEGL--IPPYGLTADTYIDLAADEEGLWAV
.. .:.: : ..:.. . . : . :. . . ::: .:: :::::
NP_055 -------FQSHIIIRFDLKTETILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDESGLWAV
300 310 320 330 340
290 300 310 320 330 340
pF1KE2 YATREDDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQ
::: .. .. ...::: .:.: : :.: :...: ::.:::::::. . .....
NP_055 YATNQNAGNIVVSRLDPVSLQTLQTWNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYA
350 360 370 380 390 400
350 360 370 380 390 400
pF1KE2 CSFDASGTLTPERAALPYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV
. .:: : : .: : .:. . : :::..: ::::..:.::.:.. .
NP_055 YQTNAS---TYEYIDIP-FQNKYSHISMLDYNPKDRALYAWNNGHQILYNVTLFHVIRSD
410 420 430 440 450 460
NP_055 EL
>>NP_001269540 (OMIM: 605366) noelin isoform 4 precursor (485 aa)
initn: 487 init1: 228 opt: 354 Z-score: 389.1 bits: 81.2 E(85289): 6.2e-15
Smith-Waterman score: 520; 28.5% identity (57.4% similar) in 383 aa overlap (27-399:122-476)
10 20 30 40 50
pF1KE2 MGPSTPLLILFLLSWSGPLQGQQHHLVEYMERRLAALEERLAQCQDQSSRHAA-EL
:: :: .. .:: .. : ... ..: : ..
NP_001 KQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQF
100 110 120 130 140 150
60 70 80 90 100 110
pF1KE2 RDFKNKM---LPLLEVAEKEREALRTEADTISGRVDRLEREVDYLETQNPALPCVEFDEK
. .: :: ::. : :. ...: . .... .. :. . . ..::
NP_001 KAIKAKMDELRPLIPVLEE----YKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDEL
160 170 180 190 200
120 130 140 150 160 170
pF1KE2 VTGGPGTKGKGRRNEKYDMVTDCGYTISQVRSMKILKRFGGPAGLWTKDPLGQT--EKIY
. . . . : . :: .. . . .: :. : : :::. ....
NP_001 QSRVSNLEERLRACMQK---LACG-KLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVW
210 220 230 240 250 260
180 190 200 210 220
pF1KE2 VLDGTQNDTAFV--FPRLRDFTLAMAARKASRVRVPFPWVGTGQLVYGGFLYFARRPPGR
.:: .:. :: . . :: : . . . :.: :: ::::.::.: .:: .
NP_001 YMDGYHNNR-FVREYKSMVDF---MNTDNFTSHRLPHPWSGTGQVVYNGSIYFNK-----
270 280 290 300 310
230 240 250 260 270 280
pF1KE2 PGGGGEMENTLQLIKFHLANRTVVDSSVFPAEGL--IPPYGLTADTYIDLAADEEGLWAV
.. .:.: : ..:.. . . : . :. . . ::: .:: :::::
NP_001 -------FQSHIIIRFDLKTETILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDESGLWAV
320 330 340 350 360
290 300 310 320 330 340
pF1KE2 YATREDDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQ
::: .. .. ...::: .:.: : :.: :...: ::.:::::::. . .....
NP_001 YATNQNAGNIVVSRLDPVSLQTLQTWNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYA
370 380 390 400 410 420
350 360 370 380 390 400
pF1KE2 CSFDASGTLTPERAALPYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV
. .:: : : .: : .:. . : :::..: ::::..:.::.:.. .
NP_001 YQTNAS---TYEYIDIP-FQNKYSHISMLDYNPKDRALYAWNNGHQILYNVTLFHVIRSD
430 440 450 460 470 480
NP_001 EL
>>NP_000252 (OMIM: 137750,601652) myocilin precursor [Ho (504 aa)
initn: 371 init1: 226 opt: 346 Z-score: 380.1 bits: 79.6 E(85289): 2e-14
Smith-Waterman score: 438; 27.6% identity (55.4% similar) in 410 aa overlap (28-401:115-503)
10 20 30 40 50
pF1KE2 MGPSTPLLILFLLSWSGPLQGQQHHLVEYMERRLAALEERLAQCQDQSSRHAAELRD
: ..:.:..:... .:: .. ::.
NP_000 LEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRE----RDQLETQTRELET
90 100 110 120 130 140
60 70 80 90 100
pF1KE2 FKNKMLPLLEVAEKEREALRTEADTISGRVDRLEREVDYLET-QNP-------ALP----
...: : :.:.. :: : .... :.. .:: :. : : :.:
NP_000 AYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSR
150 160 170 180 190 200
110 120 130 140
pF1KE2 --------CVEFDE---KVTGGPGTKGKGRRNEKY----DMVTDCGYTI--SQVRSMKIL
. :.: ..: :... . : . : :: . .. ...
NP_000 EVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTA
210 220 230 240 250 260
150 160 170 180 190 200
pF1KE2 KRFGGPAGLWTKDPLGQ----TEKIYVLDGTQNDTAFVFPRLRDFTLAMAARKASRVRV-
. . : :.: .:: : . .: . .:. :: :. . :.:..
NP_000 ETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEY--DLISQFMQGYPSKVHIL
270 280 290 300 310
210 220 230 240 250 260
pF1KE2 PFPWVGTGQLVYGGFLYFARRPPGRPGGGGEMENTLQLIKFHLANRTVVDSSVFPAEGLI
: : .:: .::.: ::: :.: .. .:...: ..:: . .:. :
NP_000 PRPLESTGAVVYSGSLYFQ---------GAESRT---VIRYELNTETVKAEKEIPGAGYH
320 330 340 350 360
270 280 290 300 310 320
pF1KE2 P--PYGLTADTYIDLAADEEGLWAVYATREDDRHLCLAKLDPQTLDTEQQWDTPCPRENA
::. . : ::::.:: :::..:.: : . :.::.:..:. :: :.: ....
NP_000 GQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSV
370 380 390 400 410 420
330 340 350 360 370 380
pF1KE2 EAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERAALPYFPRRYGAHASLRYNPRE
::.::::::.: .. .. : .. ..: .:: . ..: : :: . . ::: :
NP_000 ANAFIICGTLYTV-SSYTSADATVNFAYD-TGTGISKTLTIP-FKNRYKYSSMIDYNPLE
430 440 450 460 470 480
390 400
pF1KE2 RQLYAWDDGYQIVYKLEMRKKEEEV
..:.:::. ...: ... :
NP_000 KKLFAWDNLNMVTYDIKLSKM
490 500
>>NP_001269644 (OMIM: 615899) olfactomedin-like protein (438 aa)
initn: 289 init1: 112 opt: 344 Z-score: 378.8 bits: 79.1 E(85289): 2.3e-14
Smith-Waterman score: 417; 29.8% identity (57.2% similar) in 292 aa overlap (116-397:169-434)
90 100 110 120 130 140
pF1KE2 RVDRLEREVDYLETQNPALPCVEFDEKVTGGPGTKGKGRRNEKYDMVTDCGYTISQVRSM
:: ....::. ..: :. :
NP_001 GTPTSIPATTTTATTTPTPTTSLLPTEPPSGPEVSSQGRE-------ASCEGTLRAVDPP
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE2 KILKRFGGPAGLWTKDPLGQTEKIYVLDGTQNDTAFVFPRLRDFTLAMAARKASRVRVPF
. .: : : ::: .. ..::: . ... : :..: .: .. ..:.
NP_001 VRHHSYGRHEGAWMKDPAARDDRIYVTNYYYGNSLVEFRNLENFK---QGRWSNMYKLPY
200 210 220 230 240
210 220 230 240 250 260
pF1KE2 PWVGTGQLVYGGFLYFARRPPGRPGGGGEMENTLQLIKFHLANRTVVDSSVFP--AEGLI
:.:::..:: : .:. : : ..::. : .: :.. ...: .
NP_001 NWIGTGHVVYQGAFYYNR------------AFTKNIIKYDLRQRFVASWALLPDVVYEDT
250 260 270 280 290
270 280 290 300 310
pF1KE2 PPYGLTADTYIDLAADEEGLWAVYATREDDRH------LCLAKLDPQTLDT--EQQWDTP
:. . . ::.:.:: :::..: . ::: . :..::: :.. : : :
NP_001 TPWKWRGHSDIDFAVDESGLWVIYPAV-DDRDEAQPEVIVLSRLDPGDLSVHRETTWKTR
300 310 320 330 340 350
320 330 340 350 360 370
pF1KE2 CPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERAALPYFPRRYGAHASL
:.. :..:: ::.: .: ..... .:: . : : : ::.. ... ...
NP_001 LRRNSYGNCFLVCGILYAV-DTYNQQEGQVAYAFD-THTGTDARPQLPFL-NEHAYTTQI
360 370 380 390 400 410
380 390 400
pF1KE2 RYNPRERQLYAWDDGYQIVYKLEMRKKEEEV
:::.:: :::::.:.:..: :
NP_001 DYNPKERVLYAWDNGHQLTYTLHFVV
420 430
>>XP_005251817 (OMIM: 615899) PREDICTED: olfactomedin-li (569 aa)
initn: 289 init1: 112 opt: 344 Z-score: 377.1 bits: 79.2 E(85289): 2.9e-14
Smith-Waterman score: 409; 31.1% identity (58.8% similar) in 257 aa overlap (151-397:328-565)
130 140 150 160 170 180
pF1KE2 GKGRRNEKYDMVTDCGYTISQVRSMKILKRFGGPAGLWTKDPLGQTEKIYVLDGTQNDTA
.: : : ::: .. ..::: . ...
XP_005 KQEVTEAVAGREASCEGTLRAVDPPVRHHSYGRHEGAWMKDPAARDDRIYVTNYYYGNSL
300 310 320 330 340 350
190 200 210 220 230 240
pF1KE2 FVFPRLRDFTLAMAARKASRVRVPFPWVGTGQLVYGGFLYFARRPPGRPGGGGEMENTLQ
: :..: .: .. ..:. :.:::..:: : .:. : : .
XP_005 VEFRNLENFK---QGRWSNMYKLPYNWIGTGHVVYQGAFYYNR------------AFTKN
360 370 380 390 400
250 260 270 280 290
pF1KE2 LIKFHLANRTVVDSSVFP--AEGLIPPYGLTADTYIDLAADEEGLWAVYATREDDRH---
.::. : .: :.. ...: . :. . . ::.:.:: :::..: . :::
XP_005 IIKYDLRQRFVASWALLPDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPAV-DDRDEAQ
410 420 430 440 450 460
300 310 320 330 340 350
pF1KE2 ---LCLAKLDPQTLDT--EQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFD
. :..::: :.. : : : :.. :..:: ::.: .: ..... .::
XP_005 PEVIVLSRLDPGDLSVHRETTWKTRLRRNSYGNCFLVCGILYAV-DTYNQQEGQVAYAFD
470 480 490 500 510 520
360 370 380 390 400
pF1KE2 ASGTLTPERAALPYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV
. : : : ::.. ... ... :::.:: :::::.:.:..: :
XP_005 -THTGTDARPQLPFL-NEHAYTTQIDYNPKERVLYAWDNGHQLTYTLHFVV
530 540 550 560
406 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:00:57 2016 done: Mon Nov 7 02:00:59 2016
Total Scan time: 8.890 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]