FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2265, 448 aa
  1>>>pF1KE2265 448 - 448 aa - 448 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0063+/-0.000366; mu= 14.1718+/- 0.023
 mean_var=78.5046+/-15.331, 0's: 0 Z-trim(114.9): 16  B-trim: 245 in 1/51
 Lambda= 0.144753
 statistics sampled from 24951 (24961) to 24951 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.293), width:  16
 Scan time:  9.430

The best scores are:                                      opt bits E(85289)
NP_060426 (OMIM: 611244) tRNA wybutosine-synthesiz ( 448) 3087 654.3 1.9e-187
NP_065861 (OMIM: 611023,616539) tRNA (guanine(37)- ( 509)  153 41.6  0.0059
XP_011535319 (OMIM: 611023,616539) PREDICTED: tRNA ( 536)  153 41.6  0.0062
XP_005267973 (OMIM: 611023,616539) PREDICTED: tRNA ( 537)  153 41.6  0.0062


>>NP_060426 (OMIM: 611244) tRNA wybutosine-synthesizing   (448 aa)
 initn: 3087 init1: 3087 opt: 3087  Z-score: 3486.3  bits: 654.3 E(85289): 1.9e-187
Smith-Waterman score: 3087; 99.8% identity (99.8% similar) in 448 aa overlap (1-448:1-448)

               10        20        30        40        50        60
pF1KE2 MRENVVVSNMERESGKPVAVVAVVTEPRFTQRYREYLQRQKLFDTQHRVEKMPDGSVALP
       ::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
NP_060 MRENVVVSNMERESGKPVAVVAVVTEPWFTQRYREYLQRQKLFDTQHRVEKMPDGSVALP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 VLGETLPEQHLQELRNRVAPGSPCMLTQLPDPVPSKRAQGCSPAQKLCLEVSRWVEGRGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VLGETLPEQHLQELRNRVAPGSPCMLTQLPDPVPSKRAQGCSPAQKLCLEVSRWVEGRGV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 KWSAELEADLPRSWQRHGNLLLLSEDCFQAKQWKNLGPELWETVALALGVQRLAKRGRVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KWSAELEADLPRSWQRHGNLLLLSEDCFQAKQWKNLGPELWETVALALGVQRLAKRGRVS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 PDGTRTPAVTLLLGDHGWVEHVDNGIRYKFDVTQCMFSFGNITEKLRVASLSCAGEVLVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PDGTRTPAVTLLLGDHGWVEHVDNGIRYKFDVTQCMFSFGNITEKLRVASLSCAGEVLVD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 LYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVALRNNLEINGVADRCQIHFGDNRKLKLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVALRNNLEINGVADRCQIHFGDNRKLKLS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 NIADRVILGLIPSSEEGWPIACQVLRQDAGGILHIHQNVESFPGKNLQALGVSKVEKEHW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NIADRVILGLIPSSEEGWPIACQVLRQDAGGILHIHQNVESFPGKNLQALGVSKVEKEHW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 LYPQQITTNQWKNGATRDSRGKMLSPATKPEWQRWAESAETRIATLLQQVHGKPWKTQIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LYPQQITTNQWKNGATRDSRGKMLSPATKPEWQRWAESAETRIATLLQQVHGKPWKTQIL
              370       380       390       400       410       420

              430       440        
pF1KE2 HIQPVKSYAPHVDHIVLDLECCPCPSVG
       ::::::::::::::::::::::::::::
NP_060 HIQPVKSYAPHVDHIVLDLECCPCPSVG
              430       440        

>>NP_065861 (OMIM: 611023,616539) tRNA (guanine(37)-N1)-  (509 aa)
 initn: 119 init1:  96 opt: 153  Z-score: 174.0  bits: 41.6 E(85289): 0.0059
Smith-Waterman score: 153; 26.2% identity (58.4% similar) in 149 aa overlap (185-332:248-393)

          160       170       180       190       200        210   
pF1KE2 NLGPELWETVALALGVQRLAKRGRVSPDGTRTPAVTLLLGDHGWVEHV-DNGIRYKFDVT
                                     :.  . .: :... . .: .:.  :.:: .
NP_065 FKHLIGQVMIDKNPGITSAVNKINNIDNMYRNFQMEVLSGEQNMMTKVRENNYTYEFDFS
       220       230       240       250       260       270       

           220       230       240       250       260       270   
pF1KE2 QCMFSFGNITEKLRVASLSCAGEVLVDLYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVA
       . ...    ::. :.. :   :.:: :..::.: :..:  :      : : . ::..   
NP_065 KVYWNPRLSTEHSRITELLKPGDVLFDVFAGVGPFAIP--VAKKNCTVFANDLNPESHKW
       280       290       300       310         320       330     

           280       290       300       310       320       330   
pF1KE2 LRNNLEINGVADRCQIHFGDNRKLKLSNIADRVILGLIPSSEEGWPIACQVLRQDAGGIL
       :  : ..: : .. ..   :.. . :.. . . .. :.  :.:  : .  :.   : .: 
NP_065 LLYNCKLNKVDQKVKVFNLDGKDF-LQGPVKEELMQLLGLSKERKPSVHVVMNLPAKAIE
         340       350        360       370       380       390    

           340       350       360       370       380       390   
pF1KE2 HIHQNVESFPGKNLQALGVSKVEKEHWLYPQQITTNQWKNGATRDSRGKMLSPATKPEWQ
                                                                   
NP_065 FLSAFKWLLDGQPCSSEFLPIVHCYSFSKDANPAEDVRQRAGAVLGISLEACSSVHLVRN
          400       410       420       430       440       450    

>>XP_011535319 (OMIM: 611023,616539) PREDICTED: tRNA (gu  (536 aa)
 initn: 120 init1:  96 opt: 153  Z-score: 173.7  bits: 41.6 E(85289): 0.0062
Smith-Waterman score: 153; 26.2% identity (58.4% similar) in 149 aa overlap (185-332:275-420)

          160       170       180       190       200        210   
pF1KE2 NLGPELWETVALALGVQRLAKRGRVSPDGTRTPAVTLLLGDHGWVEHV-DNGIRYKFDVT
                                     :.  . .: :... . .: .:.  :.:: .
XP_011 FKHLIGQVMIDKNPGITSAVNKINNIDNMYRNFQMEVLSGEQNMMTKVRENNYTYEFDFS
          250       260       270       280       290       300    

           220       230       240       250       260       270   
pF1KE2 QCMFSFGNITEKLRVASLSCAGEVLVDLYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVA
       . ...    ::. :.. :   :.:: :..::.: :..:  :      : : . ::..   
XP_011 KVYWNPRLSTEHSRITELLKPGDVLFDVFAGVGPFAIP--VAKKNCTVFANDLNPESHKW
          310       320       330       340         350       360  

           280       290       300       310       320       330   
pF1KE2 LRNNLEINGVADRCQIHFGDNRKLKLSNIADRVILGLIPSSEEGWPIACQVLRQDAGGIL
       :  : ..: : .. ..   :.. . :.. . . .. :.  :.:  : .  :.   : .: 
XP_011 LLYNCKLNKVDQKVKVFNLDGKDF-LQGPVKEELMQLLGLSKERKPSVHVVMNLPAKAIE
            370       380        390       400       410       420 

           340       350       360       370       380       390   
pF1KE2 HIHQNVESFPGKNLQALGVSKVEKEHWLYPQQITTNQWKNGATRDSRGKMLSPATKPEWQ
                                                                   
XP_011 FLSAFKWLLDGQPCSSEFLPIVHCYSFSKDANPAEDVRQRAGAVLGISLEACSSVHLVRN
             430       440       450       460       470       480 

>>XP_005267973 (OMIM: 611023,616539) PREDICTED: tRNA (gu  (537 aa)
 initn: 119 init1:  96 opt: 153  Z-score: 173.7  bits: 41.6 E(85289): 0.0062
Smith-Waterman score: 153; 26.2% identity (58.4% similar) in 149 aa overlap (185-332:276-421)

          160       170       180       190       200        210   
pF1KE2 NLGPELWETVALALGVQRLAKRGRVSPDGTRTPAVTLLLGDHGWVEHV-DNGIRYKFDVT
                                     :.  . .: :... . .: .:.  :.:: .
XP_005 FKHLIGQVMIDKNPGITSAVNKINNIDNMYRNFQMEVLSGEQNMMTKVRENNYTYEFDFS
         250       260       270       280       290       300     

           220       230       240       250       260       270   
pF1KE2 QCMFSFGNITEKLRVASLSCAGEVLVDLYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVA
       . ...    ::. :.. :   :.:: :..::.: :..:  :      : : . ::..   
XP_005 KVYWNPRLSTEHSRITELLKPGDVLFDVFAGVGPFAIP--VAKKNCTVFANDLNPESHKW
         310       320       330       340         350       360   

           280       290       300       310       320       330   
pF1KE2 LRNNLEINGVADRCQIHFGDNRKLKLSNIADRVILGLIPSSEEGWPIACQVLRQDAGGIL
       :  : ..: : .. ..   :.. . :.. . . .. :.  :.:  : .  :.   : .: 
XP_005 LLYNCKLNKVDQKVKVFNLDGKDF-LQGPVKEELMQLLGLSKERKPSVHVVMNLPAKAIE
           370       380        390       400       410       420  

           340       350       360       370       380       390   
pF1KE2 HIHQNVESFPGKNLQALGVSKVEKEHWLYPQQITTNQWKNGATRDSRGKMLSPATKPEWQ
                                                                   
XP_005 FLSAFKWLLDGQPCSSEFLPIVHCYSFSKDANPAEDVRQRAGAVLGISLEACSSVHLVRN
            430       440       450       460       470       480  




448 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 15:53:20 2016 done: Mon Nov  7 15:53:21 2016
 Total Scan time:  9.430 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]