Result of FASTA (omim) for
pFN21AE2258
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2258, 117 aa
1>>>pF1KE2258 117 - 117 aa - 117 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6604+/-0.000297; mu= 13.4550+/- 0.018
mean_var=54.7427+/-10.976, 0's: 0 Z-trim(116.3): 15 B-trim: 44 in 1/54
Lambda= 0.173345
statistics sampled from 27314 (27328) to 27314 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.32), width: 16
Scan time: 4.270
The best scores are: opt bits E(85289)
NP_009209 (OMIM: 605125) gamma-aminobutyric acid r ( 117) 780 202.4 1.4e-52
NP_113600 (OMIM: 607420) gamma-aminobutyric acid r ( 117) 698 181.9 2.1e-46
XP_005253401 (OMIM: 607420) PREDICTED: gamma-amino ( 146) 578 151.9 2.7e-37
NP_009216 (OMIM: 607452) gamma-aminobutyric acid r ( 117) 462 122.8 1.2e-28
XP_005273196 (OMIM: 609605) PREDICTED: microtubule ( 147) 296 81.4 4.6e-16
NP_001004343 (OMIM: 609605) microtubule-associated ( 147) 296 81.4 4.6e-16
NP_073729 (OMIM: 609604) microtubule-associated pr ( 125) 247 69.1 2e-12
NP_115903 (OMIM: 601242) microtubule-associated pr ( 121) 240 67.3 6.5e-12
XP_011527387 (OMIM: 601242) PREDICTED: microtubule ( 182) 240 67.4 9.1e-12
XP_011527385 (OMIM: 601242) PREDICTED: microtubule ( 223) 240 67.5 1.1e-11
XP_011527386 (OMIM: 601242) PREDICTED: microtubule ( 223) 240 67.5 1.1e-11
NP_852610 (OMIM: 601242) microtubule-associated pr ( 125) 223 63.1 1.3e-10
>>NP_009209 (OMIM: 605125) gamma-aminobutyric acid recep (117 aa)
initn: 780 init1: 780 opt: 780 Z-score: 1064.9 bits: 202.4 E(85289): 1.4e-52
Smith-Waterman score: 780; 100.0% identity (100.0% similar) in 117 aa overlap (1-117:1-117)
10 20 30 40 50 60
pF1KE2 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQF
10 20 30 40 50 60
70 80 90 100 110
pF1KE2 YFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 YFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
70 80 90 100 110
>>NP_113600 (OMIM: 607420) gamma-aminobutyric acid recep (117 aa)
initn: 698 init1: 698 opt: 698 Z-score: 954.1 bits: 181.9 E(85289): 2.1e-46
Smith-Waterman score: 698; 87.1% identity (96.6% similar) in 116 aa overlap (1-116:1-116)
10 20 30 40 50 60
pF1KE2 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQF
::: :::.:::: :..::::::::::::::::::::::::. ::::.:::::::::::::
NP_113 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQF
10 20 30 40 50 60
70 80 90 100 110
pF1KE2 YFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
::::::::::: ::::::::::.::::::::::::...::::.:::.:::::::::
NP_113 YFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK
70 80 90 100 110
>>XP_005253401 (OMIM: 607420) PREDICTED: gamma-aminobuty (146 aa)
initn: 578 init1: 578 opt: 578 Z-score: 790.5 bits: 151.9 E(85289): 2.7e-37
Smith-Waterman score: 578; 88.5% identity (95.8% similar) in 96 aa overlap (1-96:1-96)
10 20 30 40 50 60
pF1KE2 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQF
::: :::.:::: :..::::::::::::::::::::::::. ::::.:::::::::::::
XP_005 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQF
10 20 30 40 50 60
70 80 90 100 110
pF1KE2 YFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
::::::::::: ::::::::::.::::::::::::.
XP_005 YFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEVMVLVAQYWMPSSAVWHPLALVLD
70 80 90 100 110 120
XP_005 ALITHLRSGAEGVIYPDPLTYGSVRL
130 140
>>NP_009216 (OMIM: 607452) gamma-aminobutyric acid recep (117 aa)
initn: 483 init1: 462 opt: 462 Z-score: 635.1 bits: 122.8 E(85289): 1.2e-28
Smith-Waterman score: 462; 57.3% identity (88.0% similar) in 117 aa overlap (1-117:1-117)
10 20 30 40 50 60
pF1KE2 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQF
::...::.: .:.: :. ::: ::::::::::::. ..: :.::.:::::::.::.::
NP_009 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQF
10 20 30 40 50 60
70 80 90 100 110
pF1KE2 YFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
...:::::.: .: :.:.::....: .: ::::::.....:: :::.::: :...:.
NP_009 MWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF
70 80 90 100 110
>>XP_005273196 (OMIM: 609605) PREDICTED: microtubule-ass (147 aa)
initn: 308 init1: 138 opt: 296 Z-score: 409.3 bits: 81.4 E(85289): 4.6e-16
Smith-Waterman score: 296; 38.6% identity (76.3% similar) in 114 aa overlap (5-116:13-126)
10 20 30 40 50
pF1KE2 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKAR-IGDLDKKKYLV
.:... . :. : :: :.:...::.::. :. . ::: :.::
XP_005 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 PSDLTVGQFYFLIRKRIHLRAEDALFFFVNN-VIPPTSATMGQLYQEHHEEDFFLYIAYS
:..::. :: .::.:. ::: .:....::: . ::::...:.....:: :.:..:.
XP_005 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
70 80 90 100 110 120
pF1KE2 DESVYGL
.. ..:
XP_005 SQETFGCLESAAPRDGSSLEDRPCNPL
130 140
>>NP_001004343 (OMIM: 609605) microtubule-associated pro (147 aa)
initn: 308 init1: 138 opt: 296 Z-score: 409.3 bits: 81.4 E(85289): 4.6e-16
Smith-Waterman score: 296; 38.6% identity (76.3% similar) in 114 aa overlap (5-116:13-126)
10 20 30 40 50
pF1KE2 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKAR-IGDLDKKKYLV
.:... . :. : :: :.:...::.::. :. . ::: :.::
NP_001 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 PSDLTVGQFYFLIRKRIHLRAEDALFFFVNN-VIPPTSATMGQLYQEHHEEDFFLYIAYS
:..::. :: .::.:. ::: .:....::: . ::::...:.....:: :.:..:.
NP_001 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
70 80 90 100 110 120
pF1KE2 DESVYGL
.. ..:
NP_001 SQETFGCLESAAPRDGSSLEDRPCNPL
130 140
>>NP_073729 (OMIM: 609604) microtubule-associated protei (125 aa)
initn: 232 init1: 111 opt: 247 Z-score: 344.1 bits: 69.1 E(85289): 2e-12
Smith-Waterman score: 247; 31.3% identity (78.3% similar) in 115 aa overlap (5-117:7-121)
10 20 30 40 50
pF1KE2 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAP-KARIGDLDKKKYLVPSDLTV
.:... ::.: . . ::...: ..:::.:. . .. ::: :.:::. ...
NP_073 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 GQFYFLIRKRIHLRAEDALFFFVN-NVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYG
... .::.:..: :..:.:..:: . . .:. ....:. ...:: :::..:... ..:
NP_073 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG
70 80 90 100 110 120
pF1KE2 L
.
NP_073 MKLSV
>>NP_115903 (OMIM: 601242) microtubule-associated protei (121 aa)
initn: 223 init1: 104 opt: 240 Z-score: 334.9 bits: 67.3 E(85289): 6.5e-12
Smith-Waterman score: 240; 30.4% identity (77.4% similar) in 115 aa overlap (5-117:7-121)
10 20 30 40 50
pF1KE2 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAP-KARIGDLDKKKYLVPSDLTV
.:... : : .: ..:: ..:...:::.:. . .. ::: :.:::. ...
NP_115 MPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 GQFYFLIRKRIHLRAEDALFFFVN-NVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYG
... .::.:..: .:.:..:: . . .:. ....:.....:: :::..:... ..:
NP_115 SELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFG
70 80 90 100 110 120
pF1KE2 L
.
NP_115 F
>>XP_011527387 (OMIM: 601242) PREDICTED: microtubule-ass (182 aa)
initn: 223 init1: 104 opt: 240 Z-score: 332.3 bits: 67.4 E(85289): 9.1e-12
Smith-Waterman score: 240; 30.4% identity (77.4% similar) in 115 aa overlap (5-117:68-182)
10 20 30
pF1KE2 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVE
.:... : : .: ..:: ..:...:::.:
XP_011 RSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIE
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE2 KAP-KARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVN-NVIPPTSATMG
. . .. ::: :.:::. ...... .::.:..: .:.:..:: . . .:. ..
XP_011 RYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIA
100 110 120 130 140 150
100 110
pF1KE2 QLYQEHHEEDFFLYIAYSDESVYGL
..:.....:: :::..:... ..:.
XP_011 DIYEQEKDEDGFLYMVYASQETFGF
160 170 180
>>XP_011527385 (OMIM: 601242) PREDICTED: microtubule-ass (223 aa)
initn: 223 init1: 104 opt: 240 Z-score: 331.0 bits: 67.5 E(85289): 1.1e-11
Smith-Waterman score: 240; 30.4% identity (77.4% similar) in 115 aa overlap (5-117:109-223)
10 20 30
pF1KE2 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVE
.:... : : .: ..:: ..:...:::.:
XP_011 RSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIE
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE2 KAP-KARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVN-NVIPPTSATMG
. . .. ::: :.:::. ...... .::.:..: .:.:..:: . . .:. ..
XP_011 RYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIA
140 150 160 170 180 190
100 110
pF1KE2 QLYQEHHEEDFFLYIAYSDESVYGL
..:.....:: :::..:... ..:.
XP_011 DIYEQEKDEDGFLYMVYASQETFGF
200 210 220
117 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 15:55:03 2016 done: Mon Nov 7 15:55:04 2016
Total Scan time: 4.270 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]