Result of FASTA (ccds) for
pFN21AE2255
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2255, 374 aa
1>>>pF1KE2255 374 - 374 aa - 374 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2457+/-0.000815; mu= 16.4129+/- 0.049
mean_var=97.6818+/-25.975, 0's: 0 Z-trim(107.6): 247 B-trim: 1181 in 2/50
Lambda= 0.129768
statistics sampled from 9384 (9697) to 9384 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.298), width: 16
Scan time: 2.910
The best scores are: opt bits E(32554)
CCDS1124.1 RXFP4 gene_id:339403|Hs108|chr1 ( 374) 2516 481.8 4.1e-136
CCDS3137.1 AGTR1 gene_id:185|Hs108|chr3 ( 359) 510 106.2 4.5e-23
CCDS82855.1 AGTR1 gene_id:185|Hs108|chr3 ( 388) 510 106.3 4.8e-23
CCDS82854.1 AGTR1 gene_id:185|Hs108|chr3 ( 394) 510 106.3 4.8e-23
CCDS14569.1 AGTR2 gene_id:186|Hs108|chrX ( 363) 494 103.3 3.7e-22
CCDS42856.1 SSTR4 gene_id:6754|Hs108|chr20 ( 388) 490 102.5 6.4e-22
CCDS329.1 OPRD1 gene_id:4985|Hs108|chr1 ( 372) 482 101.0 1.8e-21
CCDS2516.1 ACKR3 gene_id:57007|Hs108|chr2 ( 362) 473 99.3 5.6e-21
CCDS6151.1 NPBWR1 gene_id:2831|Hs108|chr8 ( 328) 467 98.2 1.1e-20
CCDS13556.1 OPRL1 gene_id:4987|Hs108|chr20 ( 370) 455 96.0 5.8e-20
CCDS10429.1 SSTR5 gene_id:6755|Hs108|chr16 ( 364) 453 95.6 7.5e-20
CCDS55069.1 OPRM1 gene_id:4988|Hs108|chr6 ( 389) 451 95.2 1e-19
CCDS47508.1 OPRM1 gene_id:4988|Hs108|chr6 ( 392) 451 95.2 1e-19
CCDS47505.1 OPRM1 gene_id:4988|Hs108|chr6 ( 397) 451 95.2 1e-19
CCDS55070.1 OPRM1 gene_id:4988|Hs108|chr6 ( 400) 451 95.2 1e-19
CCDS47506.1 OPRM1 gene_id:4988|Hs108|chr6 ( 403) 451 95.3 1e-19
CCDS47504.1 OPRM1 gene_id:4988|Hs108|chr6 ( 406) 451 95.3 1e-19
CCDS43517.1 OPRM1 gene_id:4988|Hs108|chr6 ( 418) 451 95.3 1.1e-19
CCDS47507.1 OPRM1 gene_id:4988|Hs108|chr6 ( 420) 451 95.3 1.1e-19
CCDS43518.1 OPRM1 gene_id:4988|Hs108|chr6 ( 446) 451 95.3 1.1e-19
CCDS47503.1 OPRM1 gene_id:4988|Hs108|chr6 ( 493) 451 95.3 1.2e-19
CCDS46420.1 CXCR4 gene_id:7852|Hs108|chr2 ( 352) 447 94.4 1.6e-19
CCDS33295.1 CXCR4 gene_id:7852|Hs108|chr2 ( 356) 447 94.4 1.6e-19
CCDS1405.1 GPR25 gene_id:2848|Hs108|chr1 ( 361) 447 94.5 1.6e-19
CCDS13944.1 SSTR3 gene_id:6753|Hs108|chr22 ( 418) 445 94.1 2.3e-19
CCDS2733.1 CCR9 gene_id:10803|Hs108|chr3 ( 357) 433 91.8 9.9e-19
CCDS2732.1 CCR9 gene_id:10803|Hs108|chr3 ( 369) 433 91.8 1e-18
CCDS9942.1 BDKRB2 gene_id:624|Hs108|chr14 ( 391) 433 91.9 1.1e-18
CCDS14416.1 CXCR3 gene_id:2833|Hs108|chrX ( 368) 432 91.7 1.2e-18
CCDS48135.1 CXCR3 gene_id:2833|Hs108|chrX ( 415) 432 91.7 1.2e-18
CCDS2656.1 CCR4 gene_id:1233|Hs108|chr3 ( 360) 426 90.5 2.5e-18
CCDS12012.1 GALR1 gene_id:2587|Hs108|chr18 ( 349) 425 90.3 2.8e-18
CCDS2739.1 CCR5 gene_id:1234|Hs108|chr3 ( 352) 425 90.3 2.8e-18
CCDS46813.1 CCR2 gene_id:729230|Hs108|chr3 ( 360) 424 90.1 3.2e-18
CCDS13557.1 NPBWR2 gene_id:2832|Hs108|chr20 ( 333) 419 89.2 5.8e-18
CCDS9666.1 SSTR1 gene_id:6751|Hs108|chr14 ( 391) 413 88.1 1.4e-17
CCDS8402.1 CXCR5 gene_id:643|Hs108|chr11 ( 372) 410 87.5 2e-17
CCDS43078.1 CCR2 gene_id:729230|Hs108|chr3 ( 374) 410 87.5 2e-17
CCDS13958.1 GALR3 gene_id:8484|Hs108|chr22 ( 368) 408 87.2 2.6e-17
CCDS55071.1 OPRM1 gene_id:4988|Hs108|chr6 ( 300) 405 86.5 3.3e-17
CCDS55068.1 OPRM1 gene_id:4988|Hs108|chr6 ( 319) 405 86.5 3.5e-17
CCDS2368.1 GPR1 gene_id:2825|Hs108|chr2 ( 355) 404 86.4 4.3e-17
CCDS43069.1 CX3CR1 gene_id:1524|Hs108|chr3 ( 355) 403 86.2 4.8e-17
CCDS11691.1 SSTR2 gene_id:6752|Hs108|chr17 ( 369) 403 86.2 5e-17
CCDS54571.1 CX3CR1 gene_id:1524|Hs108|chr3 ( 387) 403 86.2 5.1e-17
CCDS9943.1 BDKRB1 gene_id:623|Hs108|chr14 ( 353) 402 86.0 5.5e-17
CCDS33063.1 C5AR1 gene_id:728|Hs108|chr19 ( 350) 401 85.8 6.2e-17
CCDS6152.1 OPRK1 gene_id:4986|Hs108|chr8 ( 380) 399 85.5 8.5e-17
CCDS2737.1 CCR1 gene_id:1230|Hs108|chr3 ( 355) 390 83.8 2.6e-16
CCDS2684.1 CCR8 gene_id:1237|Hs108|chr3 ( 355) 380 81.9 9.6e-16
>>CCDS1124.1 RXFP4 gene_id:339403|Hs108|chr1 (374 aa)
initn: 2516 init1: 2516 opt: 2516 Z-score: 2557.1 bits: 481.8 E(32554): 4.1e-136
Smith-Waterman score: 2516; 99.7% identity (99.7% similar) in 374 aa overlap (1-374:1-374)
10 20 30 40 50 60
pF1KE2 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLGNLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLGNLAV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKMVLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKMVLTA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 TVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPTAVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPTAVFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VEGEVCGVRLCLLRFPSRYWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFLQRRQRRRQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VEGEVCGVRLCLLRFPSRYWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFLQRRQRRRQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTYVFPVTTCLAHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTYVFPVTTCLAHS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQVALKQVGRRWVASNPRESR
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
CCDS11 NSCLNPVLYCLLRREPRQALAGTFRDLRLRLWPQGGGWVQQVALKQVGRRWVASNPRESR
310 320 330 340 350 360
370
pF1KE2 PSTLLTNLDRGTPG
::::::::::::::
CCDS11 PSTLLTNLDRGTPG
370
>>CCDS3137.1 AGTR1 gene_id:185|Hs108|chr3 (359 aa)
initn: 271 init1: 236 opt: 510 Z-score: 527.6 bits: 106.2 E(32554): 4.5e-23
Smith-Waterman score: 510; 28.4% identity (63.5% similar) in 299 aa overlap (27-315:16-308)
10 20 30 40 50 60
pF1KE2 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLGNLAV
:: : . . .:. :... ..:..:: :
CCDS31 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLV
10 20 30 40
70 80 90 100 110 120
pF1KE2 LWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKMVLTA
. :. . ...:..::::::: . ::::.::. .:....::::. :::.. ..
CCDS31 VIVIYFYMKLK--TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASAS
50 60 70 80 90 100
130 140 150 160 170
pF1KE2 TVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPTA---
. .:.:::.::.: ::. :: ... . ... :... . .: :.:...:.
CCDS31 VSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 -VFGVEGEVCGVRLCLLRFPSR---YWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFLQR
:: .:. .. .: ... :. .: : . .:.:. :. .: ::: :. :..
CCDS31 NVFFIEN--TNITVCAFHYESQNSTLPIG-LGLTKNILGFLFPFLIILTSYTLIWKALKK
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE2 R---QRRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTYV
:. . . . . . .: ::. :.:... :. ::... .. . . : .
CCDS31 AYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIR-DCRIADIVDTA
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE2 FPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQVALKQVGRR
.:.: :.:. :.::::..: .: ..
CCDS31 MPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSD
290 300 310 320 330 340
>>CCDS82855.1 AGTR1 gene_id:185|Hs108|chr3 (388 aa)
initn: 271 init1: 236 opt: 510 Z-score: 527.2 bits: 106.3 E(32554): 4.8e-23
Smith-Waterman score: 510; 28.4% identity (63.5% similar) in 299 aa overlap (27-315:45-337)
10 20 30 40 50
pF1KE2 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLG
:: : . . .:. :... ..:..:
CCDS82 VFDIVFATNSTQVIKMILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFG
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE2 NLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKM
: :. :. . ...:..::::::: . ::::.::. .:....::::. :::.
CCDS82 NSLVVIVIYFYMKLK--TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKI
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE2 VLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPT
. ... .:.:::.::.: ::. :: ... . ... :... . .: :.:...:.
CCDS82 ASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPA
140 150 160 170 180 190
180 190 200 210 220
pF1KE2 A----VFGVEGEVCGVRLCLLRFPSR---YWLGAYQLQRVVLAFMVPLGVITTSYLLLLA
:: .:. .. .: ... :. .: : . .:.:. :. .: ::: :.
CCDS82 IIHRNVFFIEN--TNITVCAFHYESQNSTLPIG-LGLTKNILGFLFPFLIILTSYTLIWK
200 210 220 230 240
230 240 250 260 270 280
pF1KE2 FLQRR---QRRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTI
:.. :. . . . . . .: ::. :.:... :. ::... .. . . :
CCDS82 ALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIR-DCRIADI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE2 QTYVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQVALKQ
..:.: :.:. :.::::..: .: ..
CCDS82 VDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSY
310 320 330 340 350 360
>>CCDS82854.1 AGTR1 gene_id:185|Hs108|chr3 (394 aa)
initn: 271 init1: 236 opt: 510 Z-score: 527.1 bits: 106.3 E(32554): 4.8e-23
Smith-Waterman score: 510; 28.4% identity (63.5% similar) in 299 aa overlap (27-315:51-343)
10 20 30 40 50
pF1KE2 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLG
:: : . . .:. :... ..:..:
CCDS82 VFDIVFATNSTQVIKMILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFG
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE2 NLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKM
: :. :. . ...:..::::::: . ::::.::. .:....::::. :::.
CCDS82 NSLVVIVIYFYMKLK--TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKI
90 100 110 120 130
120 130 140 150 160 170
pF1KE2 VLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPT
. ... .:.:::.::.: ::. :: ... . ... :... . .: :.:...:.
CCDS82 ASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPA
140 150 160 170 180 190
180 190 200 210 220
pF1KE2 A----VFGVEGEVCGVRLCLLRFPSR---YWLGAYQLQRVVLAFMVPLGVITTSYLLLLA
:: .:. .. .: ... :. .: : . .:.:. :. .: ::: :.
CCDS82 IIHRNVFFIEN--TNITVCAFHYESQNSTLPIG-LGLTKNILGFLFPFLIILTSYTLIWK
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE2 FLQRR---QRRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTI
:.. :. . . . . . .: ::. :.:... :. ::... .. . . :
CCDS82 ALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIR-DCRIADI
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE2 QTYVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQVALKQ
..:.: :.:. :.::::..: .: ..
CCDS82 VDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSY
320 330 340 350 360 370
>>CCDS14569.1 AGTR2 gene_id:186|Hs108|chrX (363 aa)
initn: 396 init1: 198 opt: 494 Z-score: 511.4 bits: 103.3 E(32554): 3.7e-22
Smith-Waterman score: 494; 31.4% identity (59.0% similar) in 334 aa overlap (13-335:20-342)
10 20 30 40 50
pF1KE2 MPTLNTSASPPTFFWANASGG--SVLSADDAPMPVKFLALRLMVALAYGLVGA
: .: ::. :.:. .. : .. :. .. : .. .
CCDS14 MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPIL----YYIIFV
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 IGLLGNLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGG
::.: :..:. .. : ...: :. ..::::.::: : :::.::. . . : ::
CCDS14 IGFLVNIVVVTLF--CCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 ALCKMVLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAAL
..::. . .::..::::.:: .:: :: : . . . :. : :: : :
CCDS14 VMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPL-VWCMACL
120 130 140 150 160 170
180 190 200 210 220
pF1KE2 VTVPTAVF-GVEG-EVCGVRLCLLRFPS-RY--WLGAYQLQRVVLAFMVPLGVITTSYLL
..:: : :. : :: :.. :: .: : .. :.. .:.:..:: :.: :.
CCDS14 SSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 LLAFLQRRQ---RRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNST-
. : . . . : : . . .: .:..::.: ::.:. .:. . .. ::
CCDS14 IRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVI--NSCE
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE2 FYTIQTYVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQV
.. ..: . :. .:::.:: :::.. . .: : ..:: : ::
CCDS14 VIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFR--VPITWLQGKRESMSC
300 310 320 330 340
350 360 370
pF1KE2 ALKQVGRRWVASNPRESRPSTLLTNLDRGTPG
CCDS14 RKSSSLREMETFVS
350 360
>>CCDS42856.1 SSTR4 gene_id:6754|Hs108|chr20 (388 aa)
initn: 418 init1: 216 opt: 490 Z-score: 507.0 bits: 102.5 E(32554): 6.4e-22
Smith-Waterman score: 490; 32.2% identity (61.1% similar) in 332 aa overlap (16-337:23-338)
10 20 30 40 50
pF1KE2 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALA--YGLVGA
::::.. . . . . : : :::. :.::
CCDS42 MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAG-MVAIQCIYALVCL
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 IGLLGNLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGG
.::.:: :..:. :. . .. ...:::.:: . :..:: :. .:: :::::.
CCDS42 VGLVGNALVIFVILRYAKMKTA--TNIYLLNLAVADELFMLSVPFVASSAALR-HWPFGS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 ALCKMVLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAAL
.::. ::.. ::...:.: .:.::: :: .:. .:. :.. .:.:: :. :
CCDS42 VLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLL
120 130 140 150 160 170
180 190 200 210 220
pF1KE2 VTVPTAVFGVEGEVCGVRL--CLLRFPSRYWLGAYQLQRVVLAFMVPLGVITTSYLLLL-
::.: :.:. . : . : :..: : ... . .:.:..:. .: :::..
CCDS42 VTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 -----AFLQRRQRRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTF
:. :.::.. . ..: : ..:. : :::.: .:: : ...:
CCDS42 KMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVT----------
240 250 260 270 280
290 300 310 320 330 340
pF1KE2 YTIQTYVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQVA
.... : :. :...::: ::.:: .: . :. . .. :: : .::
CCDS42 -SLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLC-LRCCLLEGAGGAEEEPL
290 300 310 320 330 340
350 360 370
pF1KE2 LKQVGRRWVASNPRESRPSTLLTNLDRGTPG
CCDS42 DYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
350 360 370 380
>>CCDS329.1 OPRD1 gene_id:4985|Hs108|chr1 (372 aa)
initn: 385 init1: 219 opt: 482 Z-score: 499.1 bits: 101.0 E(32554): 1.8e-21
Smith-Waterman score: 483; 31.7% identity (57.7% similar) in 331 aa overlap (2-312:5-321)
10 20 30 40
pF1KE2 MPTLNTSASPPTFFWANAS---------GGSVLSADDAPMPVKFLALRLMVALAYGL
:. .. .:: : :::: .:. :. . .. ::: . .. :.
CCDS32 MEPAPSAGAELQPPLF--ANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSA
10 20 30 40 50
50 60 70 80 90 100
pF1KE2 VGAIGLLGNLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWP
: :.:::::. :.. . .. . .. ..::::::: . :::: .:. .. ::
CCDS32 VCAVGLLGNVLVMFGIVRYTKMKTA--TNIYIFNLALADALATSTLPFQSAKYLMET-WP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE2 FGGALCKMVLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAA
:: ::: ::. :...::: .: .:: :: .: . . :.. .. .:.
CCDS32 FGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 AALVTVPTAVFGVEGEVCGVRLCLLRFPSR--YWLGAYQLQRVVLAFMVPLGVITTSYLL
:. : :: :..: :. .:.:.::: :: . .. ..::.::. .::. : :
CCDS32 ASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGL
180 190 200 210 220 230
230 240 250 260 270
pF1KE2 LLA------FLQRRQRRRQDSRVVARSVRILVASFFLCWFPNHV-VTLWGVLVKFDLVPW
.: .:. ... .. : ..: : ..:..: .:: : :. : .: .:: .:
CCDS32 MLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVW-TLVDID----
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE2 NSTFYTIQTYVFPVTTCLA--HSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGG
: . :.: ..:: :::::: .:
CCDS32 ----RRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFS
300 310 320 330 340
340 350 360 370
pF1KE2 WVQQVALKQVGRRWVASNPRESRPSTLLTNLDRGTPG
CCDS32 RAREATARERVTACTPSDGPGGGAAA
350 360 370
>>CCDS2516.1 ACKR3 gene_id:57007|Hs108|chr2 (362 aa)
initn: 452 init1: 209 opt: 473 Z-score: 490.1 bits: 99.3 E(32554): 5.6e-21
Smith-Waterman score: 473; 28.6% identity (59.7% similar) in 318 aa overlap (15-324:19-330)
10 20 30 40 50
pF1KE2 MPTLNTSASPPTFFWA-NASGGSVLSADDAP-MPVKFLALRLMVALAYGLVGAIGL
: :.: :... : :: : . : . .. : .. .::.
CCDS25 MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTL-SFIYIFIFVIGM
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 LGNLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALC
..: .:.:: : .. : . ...:::.::: ..::.: :.. . .::.: :
CCDS25 IANSVVVWV--NIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 KMVLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTV
:.. .:...:::..: .:: :: ... .. . . . :.. . :: : :..
CCDS25 KVTHLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSL
120 130 140 150 160 170
180 190 200 210 220
pF1KE2 PTAVF--GVEGEVCGVRLCLLRFPS---RYWLGAYQLQRVVLAFMVPLGVITTSYLLLL-
: . . : . . : .: . :: ...: :::.: ::...:.. :.::
CCDS25 PDTYYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLAR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 AFLQRRQRRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQT
:. ......:: . : :. :..::.: ::..: .. . .:.. .
CCDS25 AISASSDQEKHSSRKIIFS---YVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALF
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE2 YVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQVALKQVG
.. :: ::. . :.::::: .. :. : : .:
CCDS25 TALHVTQCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEY
300 310 320 330 340 350
350 360 370
pF1KE2 RRWVASNPRESRPSTLLTNLDRGTPG
CCDS25 SALEQSTK
360
>>CCDS6151.1 NPBWR1 gene_id:2831|Hs108|chr8 (328 aa)
initn: 437 init1: 123 opt: 467 Z-score: 484.6 bits: 98.2 E(32554): 1.1e-20
Smith-Waterman score: 510; 35.5% identity (61.2% similar) in 338 aa overlap (5-318:3-320)
10 20 30 40 50
pF1KE2 MPTLNTSASPPTFFW-ANASGGS-VLSADDA----PMPVKFLALRLMVALAYGLVGAIGL
:.: : : : ::::: . .:: ..: :.:. : . : ..:... :.::
CCDS61 MDNASFSEP---WPANASGPDPALSCSNASTLAPLPAP---LAVAVPVVYAVICAVGL
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 LGNLAVLWVLSNCARRAP--GPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGA
:: :::.:: ::: .. :..:::.:: ..:.::. :. : .::::
CCDS61 AGNSAVLYVLL----RAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLR-QWPFGEL
60 70 80 90 100
120 130 140 150 160
pF1KE2 LCKMVLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHL---SLFWARIATLAVWAAA
.::.... :...:....:..:. :: :: .:.. . .. . :: ..::::. .
CCDS61 MCKLIVAIDQYNTFSSLYFLTVMSADRYLVV-LATAESRRVAGRTYSAARAVSLAVWGIV
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE2 ALVTVPTAVFGVEGEVCGVRLCLLRFPS--RYWLGAYQLQRVVLAFMVPLGVITTSYLLL
.::..: :::. . : : :.: ::. .: : .: .::.: .:...: . : :
CCDS61 TLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTL
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE2 LAFLQR-------RQRRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWN
: :. . .: .::. : :: : .::: : :. :. : . :: : .
CCDS61 LCRLHAMRLDSHAKALERAKKRVTFLVVAIL-AVCLLCWTPYHLSTV--VALTTDL-PQT
230 240 250 260 270 280
290 300 310 320 330
pF1KE2 STFYTIQTYVFPVTTCLAHSNSCLNPVLYCLL----RREPRQALAGTFRDLRSRLWPQGG
.:. .. : :...:::::: :: .: ::. ::
CCDS61 PLVIAISYFI----TSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
290 300 310 320
340 350 360 370
pF1KE2 GWVQQVALKQVGRRWVASNPRESRPSTLLTNLDRGTPG
>>CCDS13556.1 OPRL1 gene_id:4987|Hs108|chr20 (370 aa)
initn: 389 init1: 182 opt: 455 Z-score: 471.8 bits: 96.0 E(32554): 5.8e-20
Smith-Waterman score: 476; 32.7% identity (59.7% similar) in 318 aa overlap (5-312:28-322)
10 20 30
pF1KE2 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLA
: : :: .. ::: :. : :. .:
CCDS13 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLL-NASHGAFL-----PLGLKVTI
10 20 30 40 50
40 50 60 70 80 90
pF1KE2 LRLMVALAYGLVGAIGLLGNLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFW
. :..:. : ::::: :..:. .. . .. ..::::::: . :::::
CCDS13 VGLYLAVCVG-----GLLGNCLVMYVILRHTKMKTA--TNIYIFNLALADTLVLLTLPFQ
60 70 80 90 100
100 110 120 130 140 150
pF1KE2 AAESALDFHWPFGGALCKMVLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFW
... : : ::::.:::: :.. :...: : .::.:: :: .. .
CCDS13 GTDILLGF-WPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSK
110 120 130 140 150 160
160 170 180 190 200 210
pF1KE2 ARIATLAVWAAAALVTVPTAVFGVEGEVCGVRL-CLLRFPS--RYWLGAYQLQRVVLAFM
:. ...:.:: :..: ::.:..: ..: .. ::...:. :: .. . ...:.
CCDS13 AQAVNVAIWALASVVGVPVAIMG-SAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFI
170 180 190 200 210 220
220 230 240 250 260
pF1KE2 VPLGVITTSYLLLLA------FLQRRQRRRQDSRVVARSVRILVASFFLCWFPNHVVTL-
::. ::.. : :.. .:. ... .. : ..: : ..:: : :: : .: .:
CCDS13 VPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLA
230 240 250 260 270 280
270 280 290 300 310 320
pF1KE2 WGVLVKFDLVPWNSTFYTIQTYVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDL
:. :. : . : .: . : :.. ::::::.:: .:
CCDS13 QGLGVQ----PSSETAVAILRFC----TALGYVNSCLNPILYAFLDENFKACFRKFCCAS
290 300 310 320 330
330 340 350 360 370
pF1KE2 RSRLWPQGGGWVQQVALKQVGRRWVASNPRESRPSTLLTNLDRGTPG
CCDS13 ALRRDVQVSDRVRSIAKDVALACKTSETVPRPA
340 350 360 370
374 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 07:56:26 2016 done: Sun Nov 6 07:56:27 2016
Total Scan time: 2.910 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]