Result of FASTA (omim) for
pFN21AE2246
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2246, 300 aa
1>>>pF1KE2246 300 - 300 aa - 300 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6138+/-0.000311; mu= 11.4635+/- 0.019
mean_var=143.6943+/-27.813, 0's: 0 Z-trim(122.3): 131 B-trim: 210 in 2/54
Lambda= 0.106993
statistics sampled from 40011 (40173) to 40011 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.797), E-opt: 0.2 (0.471), width: 16
Scan time: 8.290
The best scores are: opt bits E(85289)
NP_003814 (OMIM: 603361) tumor necrosis factor rec ( 300) 2139 341.0 1.8e-93
NP_002537 (OMIM: 239000,602643) tumor necrosis fac ( 401) 597 103.1 9.7e-22
NP_001057 (OMIM: 191191) tumor necrosis factor rec ( 461) 472 83.8 6.9e-16
XP_011540365 (OMIM: 191191) PREDICTED: tumor necro ( 462) 472 83.8 6.9e-16
XP_011540362 (OMIM: 191191) PREDICTED: tumor necro ( 484) 472 83.8 7.1e-16
XP_016857700 (OMIM: 191191) PREDICTED: tumor necro ( 491) 472 83.8 7.2e-16
XP_016857701 (OMIM: 191191) PREDICTED: tumor necro ( 440) 463 82.4 1.7e-15
XP_016857702 (OMIM: 191191) PREDICTED: tumor necro ( 440) 463 82.4 1.7e-15
XP_006719046 (OMIM: 600979) PREDICTED: tumor necro ( 255) 416 74.9 1.8e-13
XP_005253745 (OMIM: 600979) PREDICTED: tumor necro ( 399) 418 75.4 2e-13
NP_002333 (OMIM: 600979) tumor necrosis factor rec ( 435) 417 75.3 2.4e-13
XP_016866233 (OMIM: 605732) PREDICTED: tumor necro ( 444) 412 74.5 4.1e-13
NP_055267 (OMIM: 605732) tumor necrosis factor rec ( 655) 412 74.7 5.4e-13
NP_001257916 (OMIM: 600979) tumor necrosis factor ( 416) 405 73.4 8.3e-13
NP_003811 (OMIM: 602746) tumor necrosis factor rec ( 283) 353 65.2 1.7e-10
NP_001257878 (OMIM: 174810,602080,603499,612301) t ( 263) 342 63.5 5.1e-10
NP_001257879 (OMIM: 174810,602080,603499,612301) t ( 337) 342 63.6 6.1e-10
NP_001257880 (OMIM: 174810,602080,603499,612301) t ( 299) 340 63.3 6.9e-10
NP_003830 (OMIM: 174810,602080,603499,612301) tumo ( 616) 342 63.9 9.3e-10
XP_006711082 (OMIM: 602746) PREDICTED: tumor necro ( 197) 330 61.5 1.5e-09
NP_001284534 (OMIM: 602746) tumor necrosis factor ( 184) 325 60.7 2.4e-09
XP_011524546 (OMIM: 174810,602080,603499,612301) P ( 621) 331 62.2 3e-09
NP_001289682 (OMIM: 109535,606843) tumor necrosis ( 237) 315 59.3 8.5e-09
XP_016883624 (OMIM: 109535,606843) PREDICTED: tumo ( 323) 315 59.4 1.1e-08
XP_016883626 (OMIM: 109535,606843) PREDICTED: tumo ( 222) 308 58.2 1.7e-08
NP_001241 (OMIM: 109535,606843) tumor necrosis fac ( 277) 308 58.3 2e-08
NP_001309350 (OMIM: 109535,606843) tumor necrosis ( 281) 308 58.3 2e-08
XP_016881554 (OMIM: 174810,602080,603499,612301) P ( 566) 285 55.0 3.9e-07
NP_690593 (OMIM: 109535,606843) tumor necrosis fac ( 203) 277 53.4 4.4e-07
XP_016883625 (OMIM: 109535,606843) PREDICTED: tumo ( 289) 277 53.5 5.7e-07
XP_011540743 (OMIM: 153243) PREDICTED: tumor necro ( 594) 276 53.7 1.1e-06
NP_001234 (OMIM: 153243) tumor necrosis factor rec ( 595) 276 53.7 1.1e-06
NP_002498 (OMIM: 162010) tumor necrosis factor rec ( 427) 236 47.4 6e-05
XP_016858210 (OMIM: 602746) PREDICTED: tumor necro ( 186) 229 45.9 7.1e-05
XP_016858209 (OMIM: 602746) PREDICTED: tumor necro ( 199) 224 45.2 0.00013
XP_016857721 (OMIM: 600315,615593) PREDICTED: tumo ( 277) 220 44.7 0.00025
NP_003318 (OMIM: 600315,615593) tumor necrosis fac ( 277) 220 44.7 0.00025
XP_011540377 (OMIM: 600315,615593) PREDICTED: tumo ( 303) 220 44.7 0.00026
XP_016857720 (OMIM: 600315,615593) PREDICTED: tumo ( 303) 220 44.7 0.00026
NP_683700 (OMIM: 603905) tumor necrosis factor rec ( 234) 213 43.6 0.00046
NP_004186 (OMIM: 603905) tumor necrosis factor rec ( 241) 213 43.6 0.00047
XP_016858211 (OMIM: 603905) PREDICTED: tumor necro ( 347) 213 43.7 0.00061
NP_001307548 (OMIM: 134637,601859) tumor necrosis ( 197) 209 42.9 0.00063
NP_690611 (OMIM: 134637,601859) tumor necrosis fac ( 220) 209 42.9 0.00068
NP_690610 (OMIM: 134637,601859) tumor necrosis fac ( 314) 209 43.1 0.00087
NP_000034 (OMIM: 134637,601859) tumor necrosis fac ( 335) 209 43.1 0.00091
XP_011538069 (OMIM: 134637,601859) PREDICTED: tumo ( 350) 209 43.1 0.00094
XP_006717882 (OMIM: 134637,601859) PREDICTED: tumo ( 362) 209 43.1 0.00097
XP_011538068 (OMIM: 134637,601859) PREDICTED: tumo ( 362) 209 43.1 0.00097
XP_011538067 (OMIM: 134637,601859) PREDICTED: tumo ( 368) 209 43.1 0.00098
>>NP_003814 (OMIM: 603361) tumor necrosis factor recepto (300 aa)
initn: 2139 init1: 2139 opt: 2139 Z-score: 1799.2 bits: 341.0 E(85289): 1.8e-93
Smith-Waterman score: 2139; 100.0% identity (100.0% similar) in 300 aa overlap (1-300:1-300)
10 20 30 40 50 60
pF1KE2 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH
250 260 270 280 290 300
>>NP_002537 (OMIM: 239000,602643) tumor necrosis factor (401 aa)
initn: 637 init1: 564 opt: 597 Z-score: 511.3 bits: 103.1 E(85289): 9.7e-22
Smith-Waterman score: 597; 37.7% identity (64.5% similar) in 231 aa overlap (10-236:3-227)
10 20 30 40 50
pF1KE2 MRALEGPGLSLLCLVLALPALLPVPAVRGVAET--PTYPWRDAETGERLVCAQCPPGTFV
.::: .: ..: . . :: : : : ::...:.: .:::::..
NP_002 MNNLLCCAL---VFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYL
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 QRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTG
.. : :.:.::: ..::. :. ..: ::. .: : . . :. ::::.:.:. :
NP_002 KQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 FFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALG
. . :::.: ::::: ::. ::: .:: :. :: : :: .::. :. : ::...:
NP_002 RYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 LALNVPGSSSHDTLCTSCTGFPLSTRVPGAEE--CERAVIDFVAFQDISIKRLQRLLQAL
: :. :...::..: .: ::. : . ::.: . :.. .. . :. :.. :
NP_002 LLLTQKGNATHDNIC---SGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNL
180 190 200 210 220
240 250 260 270 280 290
pF1KE2 EAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERF
NP_002 PGTKVNAESVERIKRQHSSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGH
230 240 250 260 270 280
>>NP_001057 (OMIM: 191191) tumor necrosis factor recepto (461 aa)
initn: 446 init1: 234 opt: 472 Z-score: 406.2 bits: 83.8 E(85289): 6.9e-16
Smith-Waterman score: 472; 34.8% identity (58.1% similar) in 210 aa overlap (8-208:13-213)
10 20 30 40 50
pF1KE2 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGER---LVCAQC
:: : . :::: . : : : : : .. . :..:
NP_001 MAPVAVWAALAVGLELWAAAHALPAQV---AFTPYAPEPGSTCRLREYYDQTAQMCCSKC
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 PPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRA
:: .. : . : :.: : :::.::.. .: :. :. . :..:: .::
NP_001 SPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRI
60 70 80 90 100 110
120 130 140 150 160
pF1KE2 CRCRTGFFA----HAG--FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSE
: :: :.. . : .: .: :: :: ::: .... :.:: ::::: ..::..
NP_001 CTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTD
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 QCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISI
:.::. :.... .::..: :..::: . : . .:::
NP_001 ICRPHQICNVVA----IPGNASMDAVCTSTS--PTRSMAPGAVHLPQPVSTRSQHTQPTP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 KRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMP
NP_001 EPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKP
240 250 260 270 280 290
>>XP_011540365 (OMIM: 191191) PREDICTED: tumor necrosis (462 aa)
initn: 446 init1: 234 opt: 472 Z-score: 406.2 bits: 83.8 E(85289): 6.9e-16
Smith-Waterman score: 472; 34.8% identity (58.1% similar) in 210 aa overlap (8-208:13-213)
10 20 30 40 50
pF1KE2 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGER---LVCAQC
:: : . :::: . : : : : : .. . :..:
XP_011 MAPVAVWAALAVGLELWAAAHALPAQV---AFTPYAPEPGSTCRLREYYDQTAQMCCSKC
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 PPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRA
:: .. : . : :.: : :::.::.. .: :. :. . :..:: .::
XP_011 SPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRI
60 70 80 90 100 110
120 130 140 150 160
pF1KE2 CRCRTGFFA----HAG--FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSE
: :: :.. . : .: .: :: :: ::: .... :.:: ::::: ..::..
XP_011 CTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTD
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 QCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISI
:.::. :.... .::..: :..::: . : . .:::
XP_011 ICRPHQICNVVA----IPGNASMDAVCTSTS--PTRSMAPGAVHLPQPVSTRSQHTQPTP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 KRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMP
XP_011 EPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKP
240 250 260 270 280 290
>>XP_011540362 (OMIM: 191191) PREDICTED: tumor necrosis (484 aa)
initn: 446 init1: 234 opt: 472 Z-score: 405.9 bits: 83.8 E(85289): 7.1e-16
Smith-Waterman score: 472; 34.8% identity (58.1% similar) in 210 aa overlap (8-208:13-213)
10 20 30 40 50
pF1KE2 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGER---LVCAQC
:: : . :::: . : : : : : .. . :..:
XP_011 MAPVAVWAALAVGLELWAAAHALPAQV---AFTPYAPEPGSTCRLREYYDQTAQMCCSKC
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 PPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRA
:: .. : . : :.: : :::.::.. .: :. :. . :..:: .::
XP_011 SPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRI
60 70 80 90 100 110
120 130 140 150 160
pF1KE2 CRCRTGFFA----HAG--FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSE
: :: :.. . : .: .: :: :: ::: .... :.:: ::::: ..::..
XP_011 CTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTD
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 QCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISI
:.::. :.... .::..: :..::: . : . .:::
XP_011 ICRPHQICNVVA----IPGNASMDAVCTSTS--PTRSMAPGAVHLPQPVSTRSQHTQPTP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 KRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMP
XP_011 EPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKP
240 250 260 270 280 290
>>XP_016857700 (OMIM: 191191) PREDICTED: tumor necrosis (491 aa)
initn: 417 init1: 234 opt: 472 Z-score: 405.9 bits: 83.8 E(85289): 7.2e-16
Smith-Waterman score: 472; 34.8% identity (58.1% similar) in 210 aa overlap (8-208:13-213)
10 20 30 40 50
pF1KE2 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGER---LVCAQC
:: : . :::: . : : : : : .. . :..:
XP_016 MAPVAVWAALAVGLELWAAAHALPAQV---AFTPYAPEPGSTCRLREYYDQTAQMCCSKC
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 PPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRA
:: .. : . : :.: : :::.::.. .: :. :. . :..:: .::
XP_016 SPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRI
60 70 80 90 100 110
120 130 140 150 160
pF1KE2 CRCRTGFFA----HAG--FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSE
: :: :.. . : .: .: :: :: ::: .... :.:: ::::: ..::..
XP_016 CTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTD
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 QCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISI
:.::. :.... .::..: :..::: . : . .:::
XP_016 ICRPHQICNVVA----IPGNASMDAVCTSTS--PTRSMAPGAVHLPQPVSTRSQHTQPTP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 KRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMP
XP_016 EPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKP
240 250 260 270 280 290
>>XP_016857701 (OMIM: 191191) PREDICTED: tumor necrosis (440 aa)
initn: 414 init1: 231 opt: 463 Z-score: 399.0 bits: 82.4 E(85289): 1.7e-15
Smith-Waterman score: 463; 36.3% identity (63.1% similar) in 168 aa overlap (47-208:1-162)
20 30 40 50 60 70
pF1KE2 ALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPR
. :..: :: .. : . : :.: :
XP_016 MCCSKCSPGQHAKVFCTKTSDTVCDSCEDS
10 20 30
80 90 100 110 120 130
pF1KE2 HYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFA----HAG--FCLEHA
:::.::.. .: :. :. . :..:: .:: : :: :.. . : .:
XP_016 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE2 SCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHD
.: :: :: ::: .... :.:: ::::: ..::.. :.::. :.... .::..: :
XP_016 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVA----IPGNASMD
100 110 120 130 140
200 210 220 230 240 250
pF1KE2 TLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPEGWGPTPRAGR
..::: . : . .:::
XP_016 AVCTSTS--PTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGST
150 160 170 180 190 200
>>XP_016857702 (OMIM: 191191) PREDICTED: tumor necrosis (440 aa)
initn: 414 init1: 231 opt: 463 Z-score: 399.0 bits: 82.4 E(85289): 1.7e-15
Smith-Waterman score: 463; 36.3% identity (63.1% similar) in 168 aa overlap (47-208:1-162)
20 30 40 50 60 70
pF1KE2 ALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPR
. :..: :: .. : . : :.: :
XP_016 MCCSKCSPGQHAKVFCTKTSDTVCDSCEDS
10 20 30
80 90 100 110 120 130
pF1KE2 HYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFA----HAG--FCLEHA
:::.::.. .: :. :. . :..:: .:: : :: :.. . : .:
XP_016 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE2 SCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHD
.: :: :: ::: .... :.:: ::::: ..::.. :.::. :.... .::..: :
XP_016 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVA----IPGNASMD
100 110 120 130 140
200 210 220 230 240 250
pF1KE2 TLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPEGWGPTPRAGR
..::: . : . .:::
XP_016 AVCTSTS--PTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGST
150 160 170 180 190 200
>>XP_006719046 (OMIM: 600979) PREDICTED: tumor necrosis (255 aa)
initn: 382 init1: 182 opt: 416 Z-score: 362.8 bits: 74.9 E(85289): 1.8e-13
Smith-Waterman score: 416; 34.3% identity (55.1% similar) in 207 aa overlap (3-193:6-210)
10 20 30 40 50
pF1KE2 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPW--RDAET-----GERLVCA
: .:::. :::.: .:: . ..: . :: : .:. :.
XP_006 MLLPWATSAPGLAWGPLVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCS
10 20 30 40 50 60
60 70 80 90 100
pF1KE2 QCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYL---ERCRYCNVLCGEREEEARACHA
.:::::.:. : : :.:. : :.. :::: . :: :. . : :: : .
XP_006 RCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGL--EEIAPCTS
70 80 90 100 110
110 120 130 140 150 160
pF1KE2 THNRACRCRTGFFAHA-----GFCLEHASCPPGAGV-IAPGTPSQNTQCQPCPPGTFSAS
.. :::. :.: : : ..::::. . . . . :..: :: : :. .
XP_006 KRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNT
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 SSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAF
:: : .:::: : ::. .::... :: :
XP_006 SSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSEPALSKGVENLQALLY
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 QDISIKRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALR
XP_006 QAATGSSEASFPTLSPL
240 250
>>XP_005253745 (OMIM: 600979) PREDICTED: tumor necrosis (399 aa)
initn: 382 init1: 182 opt: 418 Z-score: 362.0 bits: 75.4 E(85289): 2e-13
Smith-Waterman score: 420; 31.9% identity (51.0% similar) in 263 aa overlap (3-249:6-240)
10 20 30 40 50
pF1KE2 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPW--RDAET-----GERLVCA
: .:::. :::.: .:: . ..: . :: : .:. :.
XP_005 MLLPWATSAPGLAWGPLVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCS
10 20 30 40 50 60
60 70 80 90 100
pF1KE2 QCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYL---ERCRYCNVLCGEREEEARACHA
.:::::.:. : : :.:. : :.. :::: . :: :. . : :: : .
XP_005 RCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGL--EEIAPCTS
70 80 90 100 110
110 120 130 140 150 160
pF1KE2 THNRACRCRTGFFAHA-----GFCLEHASCPPGAGV-IAPGTPSQNTQCQPCPPGTFSAS
.. :::. :.: : : ..::::. . . . . :..: :: : :. .
XP_005 KRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNT
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 SSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAF
:: : .:::: : ::. .::... :: : . :: :
XP_005 SSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKN----PLEPLPP---------------
180 190 200 210
230 240 250 260 270 280
pF1KE2 QDISIKRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALR
..: . :.: :.: ::.: ::
XP_005 -EMSGSLLKR------RPQGEGPNPVAGSWEPPKAHPYFPDLVQPLLPISGDVSPVSTGL
220 230 240 250 260 270
300 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:00:33 2016 done: Sun Nov 6 13:00:35 2016
Total Scan time: 8.290 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]