Result of FASTA (ccds) for
pFN21AE2245
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2245, 217 aa
1>>>pF1KE2245 217 - 217 aa - 217 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5448+/-0.000815; mu= 11.4489+/- 0.049
mean_var=63.0824+/-12.802, 0's: 0 Z-trim(106.3): 58 B-trim: 101 in 1/49
Lambda= 0.161481
statistics sampled from 8860 (8918) to 8860 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.274), width: 16
Scan time: 1.950
The best scores are: opt bits E(32554)
CCDS2289.1 DUSP19 gene_id:142679|Hs108|chr2 ( 217) 1419 339.2 1.2e-93
CCDS46469.1 DUSP19 gene_id:142679|Hs108|chr2 ( 166) 601 148.6 2.2e-36
CCDS1528.1 DUSP10 gene_id:11221|Hs108|chr1 ( 482) 344 88.9 6e-18
CCDS8157.1 SSH3 gene_id:54961|Hs108|chr11 ( 659) 332 86.1 5.5e-17
CCDS33766.2 DUSP7 gene_id:1849|Hs108|chr3 ( 419) 328 85.1 7e-17
CCDS2016.1 DUSP2 gene_id:1844|Hs108|chr2 ( 314) 313 81.6 6.1e-16
CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 ( 232) 308 80.4 1e-15
CCDS9033.1 DUSP6 gene_id:1848|Hs108|chr12 ( 381) 310 80.9 1.2e-15
CCDS14724.1 DUSP9 gene_id:1852|Hs108|chrX ( 384) 310 80.9 1.2e-15
CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 ( 235) 306 79.9 1.5e-15
CCDS82606.1 DUSP15 gene_id:128853|Hs108|chr20 ( 295) 307 80.2 1.5e-15
CCDS4380.1 DUSP1 gene_id:1843|Hs108|chr5 ( 367) 307 80.2 1.9e-15
CCDS55882.1 SSH1 gene_id:54434|Hs108|chr12 ( 692) 304 79.6 5.3e-15
CCDS53825.1 SSH1 gene_id:54434|Hs108|chr12 ( 703) 304 79.6 5.4e-15
CCDS9711.1 STYX gene_id:6815|Hs108|chr14 ( 223) 297 77.8 6e-15
CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 ( 303) 298 78.1 6.7e-15
CCDS9121.1 SSH1 gene_id:54434|Hs108|chr12 (1049) 304 79.7 7.7e-15
CCDS6072.1 DUSP4 gene_id:1846|Hs108|chr8 ( 394) 298 78.1 8.5e-15
CCDS7566.1 DUSP5 gene_id:1847|Hs108|chr10 ( 384) 294 77.2 1.6e-14
CCDS1234.1 DUSP12 gene_id:11266|Hs108|chr1 ( 340) 287 75.5 4.4e-14
CCDS11253.1 SSH2 gene_id:85464|Hs108|chr17 (1423) 290 76.5 9.7e-14
CCDS74024.1 SSH2 gene_id:85464|Hs108|chr17 (1450) 290 76.5 9.9e-14
CCDS13883.1 DUSP18 gene_id:150290|Hs108|chr22 ( 188) 278 73.4 1.1e-13
CCDS4468.1 DUSP22 gene_id:56940|Hs108|chr6 ( 184) 271 71.7 3.4e-13
CCDS69035.1 DUSP22 gene_id:56940|Hs108|chr6 ( 205) 271 71.7 3.7e-13
CCDS33418.1 DUSP28 gene_id:285193|Hs108|chr2 ( 176) 269 71.2 4.4e-13
CCDS14264.1 DUSP21 gene_id:63904|Hs108|chrX ( 190) 265 70.3 9.1e-13
CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 ( 198) 265 70.3 9.4e-13
CCDS7724.1 DUSP8 gene_id:1850|Hs108|chr11 ( 625) 269 71.4 1.4e-12
CCDS8650.1 DUSP16 gene_id:80824|Hs108|chr12 ( 665) 269 71.4 1.5e-12
CCDS7346.1 DUSP13 gene_id:51207|Hs108|chr10 ( 198) 252 67.3 7.7e-12
CCDS31224.1 DUSP13 gene_id:51207|Hs108|chr10 ( 248) 252 67.3 9.4e-12
CCDS53542.1 DUSP13 gene_id:51207|Hs108|chr10 ( 188) 247 66.1 1.6e-11
CCDS6092.1 DUSP26 gene_id:78986|Hs108|chr8 ( 211) 243 65.2 3.5e-11
CCDS31223.1 DUPD1 gene_id:338599|Hs108|chr10 ( 220) 237 63.8 9.5e-11
>>CCDS2289.1 DUSP19 gene_id:142679|Hs108|chr2 (217 aa)
initn: 1419 init1: 1419 opt: 1419 Z-score: 1794.7 bits: 339.2 E(32554): 1.2e-93
Smith-Waterman score: 1419; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KE2 MYSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDARIHVVEEVEPSSGGGCGYVQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 MYSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDARIHVVEEVEPSSGGGCGYVQDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 SSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 PETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLV
130 140 150 160 170 180
190 200 210
pF1KE2 KNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS
:::::::::::::::::::::::::::::::::::::
CCDS22 KNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS
190 200 210
>>CCDS46469.1 DUSP19 gene_id:142679|Hs108|chr2 (166 aa)
initn: 601 init1: 601 opt: 601 Z-score: 766.7 bits: 148.6 E(32554): 2.2e-36
Smith-Waterman score: 979; 76.5% identity (76.5% similar) in 217 aa overlap (1-217:1-166)
10 20 30 40 50 60
pF1KE2 MYSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDARIHVVEEVEPSSGGGCGYVQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MYSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDARIHVVEEVEPSSGGGCGYVQDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDL
:::::::::::::::::::::::::::::::
CCDS46 SSDLQVGVIKPWLLLGSQDAAHDLDTLKKNK-----------------------------
70 80 90
130 140 150 160 170 180
pF1KE2 PETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLV
::::::::::::::::::::::::::::::::::::::
CCDS46 ----------------------DGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLV
100 110 120
190 200 210
pF1KE2 KNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS
:::::::::::::::::::::::::::::::::::::
CCDS46 KNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS
130 140 150 160
>>CCDS1528.1 DUSP10 gene_id:11221|Hs108|chr1 (482 aa)
initn: 354 init1: 277 opt: 344 Z-score: 435.7 bits: 88.9 E(32554): 6e-18
Smith-Waterman score: 344; 39.6% identity (71.1% similar) in 149 aa overlap (69-212:325-470)
40 50 60 70 80 90
pF1KE2 RIHVVEEVEPSSGGGCGYVQDLSSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNV
: :.:.::... :.::::... .. ...::
CCDS15 EVGGGASAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINV
300 310 320 330 340 350
100 110 120 130 140 150
pF1KE2 A-----YGVENAFLSDFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAG
. : :... :.:: . : . :. .:: : :::::::.. .:.::.::
CCDS15 TTHLPLYHYEKGL---FNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAG
360 370 380 390 400 410
160 170 180 190 200 210
pF1KE2 VSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQEGKESNKCDRIQ
:::.:.:::..::. . ..:.:...::. :: : :: .:: :: ..: ... ::
CCDS15 VSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRIL
420 430 440 450 460 470
pF1KE2 ENSS
CCDS15 TPKLMGVETVV
480
>>CCDS8157.1 SSH3 gene_id:54961|Hs108|chr11 (659 aa)
initn: 332 init1: 332 opt: 332 Z-score: 418.4 bits: 86.1 E(32554): 5.5e-17
Smith-Waterman score: 332; 40.6% identity (69.2% similar) in 133 aa overlap (69-201:332-464)
40 50 60 70 80 90
pF1KE2 RIHVVEEVEPSSGGGCGYVQDLSSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNV
: : : :::. : .:. :..:.::::::.
CCDS81 LRLGLPLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQRNRVTHILNM
310 320 330 340 350 360
100 110 120 130 140 150
pF1KE2 AYGVENAFLSDFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAA
: ..: . :::... . : ...: .. : .::: :. . :::::. ::::.:
CCDS81 AREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSA
370 380 390 400 410 420
160 170 180 190 200 210
pF1KE2 AIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS
: :... :.. . :. .:. :.. :: :: ::..::. ::
CCDS81 ATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQSHVWEQKVG
430 440 450 460 470 480
CCDS81 GVSPEEHPAPEVSTPFPPLPPEPEGGGEEKVVGMEESQAAPKEEPGPRPRINLRGVMRSI
490 500 510 520 530 540
>>CCDS33766.2 DUSP7 gene_id:1849|Hs108|chr3 (419 aa)
initn: 322 init1: 247 opt: 328 Z-score: 416.5 bits: 85.1 E(32554): 7e-17
Smith-Waterman score: 328; 39.3% identity (69.0% similar) in 145 aa overlap (69-210:248-392)
40 50 60 70 80 90
pF1KE2 RIHVVEEVEPSSGGGCGYVQDLSSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNV
: :.: :: . .::.: : . .::::
CCDS33 DGESDRELPSSATESDGSPVPSSQPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNV
220 230 240 250 260 270
100 110 120 130 140 150
pF1KE2 AYGVENAFL--SDFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSR
. .. ::: ..::::.: : : :. ..::: . ::.::. : ::::: ::.::
CCDS33 TPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISR
280 290 300 310 320 330
160 170 180 190 200 210
pF1KE2 AAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQEG-KESNKCDRIQEN
........::.. . :...:...:: . .: :: .:: :: ... :. ::
CCDS33 SVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGLSSPCDNHASS
340 350 360 370 380 390
pF1KE2 SS
CCDS33 EQLYFSTPTNHNLFPLNTLEST
400 410
>>CCDS2016.1 DUSP2 gene_id:1844|Hs108|chr2 (314 aa)
initn: 293 init1: 293 opt: 313 Z-score: 399.6 bits: 81.6 E(32554): 6.1e-16
Smith-Waterman score: 313; 40.6% identity (69.2% similar) in 133 aa overlap (69-201:176-308)
40 50 60 70 80 90
pF1KE2 RIHVVEEVEPSSGGGCGYVQDLSSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNV
: :.:.::: . . ::. :. .: .:::
CCDS20 APAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLNV
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE2 AYGVENAFLSDFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAA
. . : : . : :::: . : ..: ..: : . ::. .: . : :::::.::.::.:
CCDS20 SASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSA
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE2 AIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS
.: ...::.:... . ::..::. : : :: .:: :: ..
CCDS20 TICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH
270 280 290 300 310
>>CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 (232 aa)
initn: 302 init1: 217 opt: 308 Z-score: 395.4 bits: 80.4 E(32554): 1e-15
Smith-Waterman score: 308; 37.4% identity (66.0% similar) in 147 aa overlap (67-213:4-146)
40 50 60 70 80 90
pF1KE2 DARIHVVEEVEPSSGGGCGYVQDLSSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHIL
::. : : ::. :.::: : .::.:::.
CCDS82 MTEGVL-PGLYLGNFIDAKDLDQLGRNKITHII
10 20 30
100 110 120 130 140 150
pF1KE2 NVAYGVENAFLSDFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSR
.. . . .:.:.:: : . : ::. : ..: ::..::. . . : :::: ::.::
CCDS82 SI-HESPQPLLQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE2 AAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENS
...:: ...:. .. ... .: .:: :: :: .::. . : :.. : :
CCDS82 STTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEF--GWASSQKLRRQLEE
100 110 120 130 140
pF1KE2 S
CCDS82 RFGESPFRDEEELRALLPLCKRCRQGSATSASSAGPHSAASEGTVQRLVPRTPREAHRPL
150 160 170 180 190 200
>>CCDS9033.1 DUSP6 gene_id:1848|Hs108|chr12 (381 aa)
initn: 300 init1: 233 opt: 310 Z-score: 394.5 bits: 80.9 E(32554): 1.2e-15
Smith-Waterman score: 310; 37.2% identity (69.0% similar) in 145 aa overlap (69-210:210-354)
40 50 60 70 80 90
pF1KE2 RIHVVEEVEPSSGGGCGYVQDLSSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNV
: :.: :: . .::.:.. . .::::
CCDS90 IESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNV
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE2 AYGVENAFLS--DFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSR
. .. : : . .: ::.: : : :. ..::: . ::.::. :. ::::: ::.::
CCDS90 TPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISR
240 250 260 270 280 290
160 170 180 190 200 210
pF1KE2 AAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQEG-KESNKCDRIQEN
........::.. . :...:...:: . .: :: .:: :: ... :. ::
CCDS90 SVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPA
300 310 320 330 340 350
pF1KE2 SS
CCDS90 QQLYFTTPSNQNVYQVDSLQST
360 370 380
>>CCDS14724.1 DUSP9 gene_id:1852|Hs108|chrX (384 aa)
initn: 301 init1: 252 opt: 310 Z-score: 394.4 bits: 80.9 E(32554): 1.2e-15
Smith-Waterman score: 311; 37.6% identity (65.0% similar) in 157 aa overlap (54-201:185-341)
30 40 50 60 70
pF1KE2 TTLTGKKIIETWKDARIHVVEEVEPSSGGGCGYVQDLSSDLQVGV-------IKPWLLLG
:: .. .. ::. : : : ::
CCDS14 GPVPVVGLGSLCLGSDCSDAESEADRDSMSCGLDSEGATPPPVGLRASFPVQILPNLYLG
160 170 180 190 200 210
80 90 100 110 120 130
pF1KE2 SQDAAHDLDTLKKNKVTHILNVAYGVENAFLS--DFTYKSISILDLPETNILSYFPECFE
: . .:..: : . .::::. .. : : . :: ::.: : : :. .::: .:
CCDS14 SARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIE
220 230 240 250 260 270
140 150 160 170 180 190
pF1KE2 FIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFM
::.:: .. ::::: :::::........::.. . :...:..::: . .: :: .::
CCDS14 FIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFM
280 290 300 310 320 330
200 210
pF1KE2 EQLRTYQEGKESNKCDRIQENSS
:: ..
CCDS14 GQLLDFERSLRLEERHSQEQGSGGQASAASNPPSFFTTPTSDGAFELAPT
340 350 360 370 380
>>CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 (235 aa)
initn: 302 init1: 217 opt: 306 Z-score: 392.8 bits: 79.9 E(32554): 1.5e-15
Smith-Waterman score: 306; 36.6% identity (65.5% similar) in 145 aa overlap (69-213:8-149)
40 50 60 70 80 90
pF1KE2 RIHVVEEVEPSSGGGCGYVQDLSSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNV
. : : ::. :.::: : .::.:::...
CCDS13 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISI
10 20 30
100 110 120 130 140 150
pF1KE2 AYGVENAFLSDFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAA
. . .:.:.:: : . : ::. : ..: ::..::. . . : :::: ::.::..
CCDS13 -HESPQPLLQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRST
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE2 AIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS
.:: ...:. .. ... .: .:: :: :: .::. . : :.. : :
CCDS13 TIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEF--GWASSQKLRRQLEERF
100 110 120 130 140 150
CCDS13 GESPFRDEEELRALLPLCKRCRQGSATSASSAGPHSAASEGTVQRLVPRTPREAHRPLPL
160 170 180 190 200 210
217 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:55:08 2016 done: Sun Nov 6 23:55:08 2016
Total Scan time: 1.950 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]