Result of FASTA (ccds) for
pFN21AE2244
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2244, 252 aa
1>>>pF1KE2244 252 - 252 aa - 252 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4661+/-0.000777; mu= 13.7806+/- 0.047
mean_var=64.1715+/-12.660, 0's: 0 Z-trim(108.1): 36 B-trim: 44 in 1/50
Lambda= 0.160104
statistics sampled from 9935 (9971) to 9935 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.306), width: 16
Scan time: 2.310
The best scores are: opt bits E(32554)
CCDS9500.1 FGF14 gene_id:2259|Hs108|chr13 ( 252) 1718 405.2 2.2e-113
CCDS9501.1 FGF14 gene_id:2259|Hs108|chr13 ( 247) 1225 291.3 4.2e-79
CCDS3301.1 FGF12 gene_id:2257|Hs108|chr3 ( 243) 938 225.0 3.7e-59
CCDS46983.1 FGF12 gene_id:2257|Hs108|chr3 ( 181) 933 223.8 6.4e-59
CCDS55511.1 FGF13 gene_id:2258|Hs108|chrX ( 226) 931 223.4 1.1e-58
CCDS55513.1 FGF13 gene_id:2258|Hs108|chrX ( 255) 931 223.4 1.2e-58
CCDS14665.1 FGF13 gene_id:2258|Hs108|chrX ( 245) 919 220.6 7.9e-58
CCDS14664.1 FGF13 gene_id:2258|Hs108|chrX ( 192) 910 218.5 2.7e-57
CCDS55512.1 FGF13 gene_id:2258|Hs108|chrX ( 199) 908 218.0 3.8e-57
CCDS11105.1 FGF11 gene_id:2256|Hs108|chr17 ( 225) 780 188.5 3.4e-48
CCDS9298.1 FGF9 gene_id:2254|Hs108|chr13 ( 208) 419 105.1 4e-23
CCDS5998.1 FGF20 gene_id:26281|Hs108|chr8 ( 211) 413 103.7 1.1e-22
CCDS75996.1 FGF16 gene_id:8823|Hs108|chrX ( 207) 401 100.9 7.1e-22
CCDS34021.1 FGF5 gene_id:2250|Hs108|chr4 ( 268) 337 86.2 2.5e-17
CCDS10131.1 FGF7 gene_id:2252|Hs108|chr15 ( 194) 312 80.3 1e-15
CCDS8194.1 FGF4 gene_id:2249|Hs108|chr11 ( 206) 303 78.3 4.6e-15
CCDS12037.1 FGF22 gene_id:27006|Hs108|chr19 ( 170) 294 76.2 1.6e-14
CCDS3950.1 FGF10 gene_id:2255|Hs108|chr5 ( 208) 287 74.6 6e-14
CCDS4275.1 FGF1 gene_id:2246|Hs108|chr5 ( 155) 280 72.9 1.4e-13
CCDS8527.1 FGF6 gene_id:2251|Hs108|chr12 ( 208) 281 73.2 1.6e-13
CCDS8195.1 FGF3 gene_id:2248|Hs108|chr11 ( 239) 248 65.6 3.5e-11
CCDS34059.1 FGF2 gene_id:2247|Hs108|chr4 ( 288) 243 64.5 9.2e-11
>>CCDS9500.1 FGF14 gene_id:2259|Hs108|chr13 (252 aa)
initn: 1718 init1: 1718 opt: 1718 Z-score: 2148.9 bits: 405.2 E(32554): 2.2e-113
Smith-Waterman score: 1718; 100.0% identity (100.0% similar) in 252 aa overlap (1-252:1-252)
10 20 30 40 50 60
pF1KE2 MVKPVPLFRRTDFKLLLCNHKDLFFLRVSKLLDCFSPKSMWFLWNIFSKGTHMLQCLCGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 MVKPVPLFRRTDFKLLLCNHKDLFFLRVSKLLDCFSPKSMWFLWNIFSKGTHMLQCLCGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SLKKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 SLKKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 IQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 IQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 NKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 NKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIM
190 200 210 220 230 240
250
pF1KE2 NGGKPVNKSKTT
::::::::::::
CCDS95 NGGKPVNKSKTT
250
>>CCDS9501.1 FGF14 gene_id:2259|Hs108|chr13 (247 aa)
initn: 1223 init1: 1223 opt: 1225 Z-score: 1533.6 bits: 291.3 E(32554): 4.2e-79
Smith-Waterman score: 1225; 96.9% identity (97.4% similar) in 192 aa overlap (62-252:56-247)
40 50 60 70 80 90
pF1KE2 LDCFSPKSMWFLWNIFSKGTHMLQCLCGKSLKKNK-NPTDPQLKGIVTRLYCRQGYYLQM
::: . :::::::::::::::::::::
CCDS95 ASRRRSSPSKNRGLCNGNLVDIFSKVRIFGLKKRRLRRQDPQLKGIVTRLYCRQGYYLQM
30 40 50 60 70 80
100 110 120 130 140 150
pF1KE2 HPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 HPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKF
90 100 110 120 130 140
160 170 180 190 200 210
pF1KE2 KESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 KESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAM
150 160 170 180 190 200
220 230 240 250
pF1KE2 YREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
::::::::::::::::::::::::::::::::::::::::::
CCDS95 YREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
210 220 230 240
>>CCDS3301.1 FGF12 gene_id:2257|Hs108|chr3 (243 aa)
initn: 924 init1: 886 opt: 938 Z-score: 1175.5 bits: 225.0 E(32554): 3.7e-59
Smith-Waterman score: 938; 71.4% identity (88.3% similar) in 196 aa overlap (57-251:54-243)
30 40 50 60 70 80
pF1KE2 RVSKLLDCFSPKSMWFLWNIFSKGTHMLQCLC-GKSLKKNKNPTDPQLKGIVTRLYCRQG
.: :.. . : .::::::::::. .::
CCDS33 VSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKRPVRRRP-EPQLKGIVTRLFSQQG
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE2 YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFT
:.:::::::..:::::.... :::::::::::::::::::..::.::::::::: :..::
CCDS33 YFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFT
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE2 PECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKP
::::::::::::::::::: :::::::::::::::::::: :::::::::::..::.:::
CCDS33 PECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKP
150 160 170 180 190 200
210 220 230 240 250
pF1KE2 LEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
.:: ::::::::..:: : : :...:.. ::::: ::...:
CCDS33 IEVCMYREPSLHEIGE---KQG--RSRKSSGTPTMNGGKVVNQDST
210 220 230 240
>>CCDS46983.1 FGF12 gene_id:2257|Hs108|chr3 (181 aa)
initn: 924 init1: 886 opt: 933 Z-score: 1171.2 bits: 223.8 E(32554): 6.4e-59
Smith-Waterman score: 933; 75.3% identity (91.2% similar) in 182 aa overlap (70-251:5-181)
40 50 60 70 80 90
pF1KE2 MWFLWNIFSKGTHMLQCLCGKSLKKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGT
.::::::::::. .:::.:::::::..:::
CCDS46 MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGT
10 20 30
100 110 120 130 140 150
pF1KE2 KDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYY
::.... :::::::::::::::::::..::.::::::::: :..::::::::::::::::
CCDS46 KDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYY
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE2 VIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDV
::::: :::::::::::::::::::: :::::::::::..::.:::.:: ::::::::..
CCDS46 VIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEI
100 110 120 130 140 150
220 230 240 250
pF1KE2 GETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
:: : : :...:.. ::::: ::...:
CCDS46 GE---KQGR--SRKSSGTPTMNGGKVVNQDST
160 170 180
>>CCDS55511.1 FGF13 gene_id:2258|Hs108|chrX (226 aa)
initn: 938 init1: 902 opt: 931 Z-score: 1167.2 bits: 223.4 E(32554): 1.1e-58
Smith-Waterman score: 931; 66.3% identity (86.5% similar) in 208 aa overlap (47-252:19-226)
20 30 40 50 60 70
pF1KE2 LCNHKDLFFLRVSKLLDCFSPKSMWFLWNIFSKGTHMLQCLCGKSL--KKNKNPTDPQLK
: : . : :.. :.: .: .::::
CCDS55 MLRQDSIQSAELKKKESPFRAKCHEIFCCPLKQVHHKENTEPEEPQLK
10 20 30 40
80 90 100 110 120 130
pF1KE2 GIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNG
::::.:: ::::.::.. ::..:::::.... ::::::::::::::::::.: ::.:::.
CCDS55 GIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNS
50 60 70 80 90 100
140 150 160 170 180 190
pF1KE2 EGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKK
::::: :::::::::::::::::::: ::::.::::.:::.:.:::::::. ::::.:::
CCDS55 EGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK
110 120 130 140 150 160
200 210 220 230 240 250
pF1KE2 TKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
.:::::::::::.::::.::::::. : . . ::.:: :.:...:::: ......:
CCDS55 NKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHNEST
170 180 190 200 210 220
>>CCDS55513.1 FGF13 gene_id:2258|Hs108|chrX (255 aa)
initn: 938 init1: 902 opt: 931 Z-score: 1166.4 bits: 223.4 E(32554): 1.2e-58
Smith-Waterman score: 931; 66.3% identity (86.5% similar) in 208 aa overlap (47-252:48-255)
20 30 40 50 60 70
pF1KE2 LCNHKDLFFLRVSKLLDCFSPKSMWFLWNIFSKGTHMLQCLCGKSL--KKNKNPTDPQLK
: : . : :.. :.: .: .::::
CCDS55 LDDAPPGTQEYIMLRQDSIQSAELKKKESPFRAKCHEIFCCPLKQVHHKENTEPEEPQLK
20 30 40 50 60 70
80 90 100 110 120 130
pF1KE2 GIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNG
::::.:: ::::.::.. ::..:::::.... ::::::::::::::::::.: ::.:::.
CCDS55 GIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNS
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE2 EGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKK
::::: :::::::::::::::::::: ::::.::::.:::.:.:::::::. ::::.:::
CCDS55 EGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE2 TKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
.:::::::::::.::::.::::::. : . . ::.:: :.:...:::: ......:
CCDS55 NKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHNEST
200 210 220 230 240 250
>>CCDS14665.1 FGF13 gene_id:2258|Hs108|chrX (245 aa)
initn: 921 init1: 902 opt: 919 Z-score: 1151.7 bits: 220.6 E(32554): 7.9e-58
Smith-Waterman score: 919; 65.9% identity (87.0% similar) in 208 aa overlap (45-252:44-245)
20 30 40 50 60 70
pF1KE2 LLLCNHKDLFFLRVSKLLDCFSPKSMWFLWNIFSKGTHMLQCLCGKSLKKNKNPTDPQLK
:.::. : :.. .. . : .::::
CCDS14 RQAREREKSNACKCVSSPSKGKTSCDKNKLNVFSRVK-----LFGSKKRRRRRP-EPQLK
20 30 40 50 60
80 90 100 110 120 130
pF1KE2 GIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNG
::::.:: ::::.::.. ::..:::::.... ::::::::::::::::::.: ::.:::.
CCDS14 GIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNS
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE2 EGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKK
::::: :::::::::::::::::::: ::::.::::.:::.:.:::::::. ::::.:::
CCDS14 EGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE2 TKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
.:::::::::::.::::.::::::. : . . ::.:: :.:...:::: ......:
CCDS14 NKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHNEST
190 200 210 220 230 240
>>CCDS14664.1 FGF13 gene_id:2258|Hs108|chrX (192 aa)
initn: 938 init1: 902 opt: 910 Z-score: 1142.1 bits: 218.5 E(32554): 2.7e-57
Smith-Waterman score: 910; 70.6% identity (91.4% similar) in 187 aa overlap (66-252:6-192)
40 50 60 70 80 90
pF1KE2 SPKSMWFLWNIFSKGTHMLQCLCGKSLKKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGA
:. ..::::::::.:: ::::.::.. ::.
CCDS14 MALLRKSYSEPQLKGIVTKLYSRQGYHLQLQADGT
10 20 30
100 110 120 130 140 150
pF1KE2 LDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVF
.:::::.... ::::::::::::::::::.: ::.:::.::::: :::::::::::::::
CCDS14 IDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTPECKFKESVF
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE2 ENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPS
::::: ::::.::::.:::.:.:::::::. ::::.:::.:::::::::::.::::.:::
CCDS14 ENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPS
100 110 120 130 140 150
220 230 240 250
pF1KE2 LHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
:::. : . . ::.:: :.:...:::: ......:
CCDS14 LHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHNEST
160 170 180 190
>>CCDS55512.1 FGF13 gene_id:2258|Hs108|chrX (199 aa)
initn: 938 init1: 902 opt: 908 Z-score: 1139.4 bits: 218.0 E(32554): 3.8e-57
Smith-Waterman score: 908; 69.6% identity (91.1% similar) in 191 aa overlap (63-252:9-199)
40 50 60 70 80 90
pF1KE2 DCFSPKSMWFLWNIFSKGTHMLQCLCGKSLKKNKNPT-DPQLKGIVTRLYCRQGYYLQMH
:..:. . .::::::::.:: ::::.::..
CCDS55 MSGKVTKPKEEKDASKEPQLKGIVTKLYSRQGYHLQLQ
10 20 30
100 110 120 130 140 150
pF1KE2 PDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFK
::..:::::.... ::::::::::::::::::.: ::.:::.::::: :::::::::::
CCDS55 ADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTPECKFK
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE2 ESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMY
::::::::: ::::.::::.:::.:.:::::::. ::::.:::.:::::::::::.::::
CCDS55 ESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPLKVAMY
100 110 120 130 140 150
220 230 240 250
pF1KE2 REPSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
.::::::. : . . ::.:: :.:...:::: ......:
CCDS55 KEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHNEST
160 170 180 190
>>CCDS11105.1 FGF11 gene_id:2256|Hs108|chr17 (225 aa)
initn: 771 init1: 771 opt: 780 Z-score: 978.8 bits: 188.5 E(32554): 3.4e-48
Smith-Waterman score: 780; 65.7% identity (85.7% similar) in 175 aa overlap (57-230:52-225)
30 40 50 60 70 80
pF1KE2 RVSKLLDCFSPKSMWFLWNIFSKGTHMLQCLCG-KSLKKNKNPTDPQLKGIVTRLYCRQG
::: . . ...: .::::::::.:.::::
CCDS11 RPVSAQRRVCPRGTKSLCQKQLLILLSKVRLCGGRPARPDRGP-EPQLKGIVTKLFCRQG
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE2 YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFT
.::: .:::...:: .:... : :::::::::::.::..: : :.:::.:: :: : ::
CCDS11 FYLQANPDGSIQGTPEDTSSFTHFNLIPVGLRVVTIQSAKLGHYMAMNAEGLLYSSPHFT
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE2 PECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKP
::.::: :::::::.:.: ::::..:::::.:::.::::.:::::::::: :::::::
CCDS11 AECRFKECVFENYYVLYASALYRQRRSGRAWYLGLDKEGQVMKGNRVKKTKAAAHFLPKL
150 160 170 180 190 200
210 220 230 240 250
pF1KE2 LEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
::::::.:::::.: :. :. .:
CCDS11 LEVAMYQEPSLHSVPEASPSSPPAP
210 220
252 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:32:50 2016 done: Sun Nov 6 14:32:51 2016
Total Scan time: 2.310 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]