Result of FASTA (ccds) for
pFN21AE2234
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2234, 263 aa
1>>>pF1KE2234 263 - 263 aa - 263 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4313+/-0.000787; mu= 14.4260+/- 0.047
mean_var=78.2714+/-15.890, 0's: 0 Z-trim(109.5): 65 B-trim: 2 in 1/50
Lambda= 0.144968
statistics sampled from 10830 (10901) to 10830 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.335), width: 16
Scan time: 2.000
The best scores are: opt bits E(32554)
CCDS4760.1 DMB gene_id:3109|Hs108|chr6 ( 263) 1824 390.6 5.8e-109
CCDS4754.1 DOB gene_id:3112|Hs108|chr6 ( 273) 286 69.0 4e-12
CCDS4765.1 DPB1 gene_id:3115|Hs108|chr6 ( 258) 281 67.9 8e-12
CCDS59006.1 DQB1 gene_id:3119|Hs108|chr6 ( 269) 276 66.9 1.7e-11
CCDS78128.1 DQB2 gene_id:3120|Hs108|chr6 ( 264) 275 66.7 1.9e-11
CCDS47409.1 DRB1 gene_id:3123|Hs108|chr6 ( 266) 273 66.2 2.6e-11
CCDS43451.1 DQB1 gene_id:3119|Hs108|chr6 ( 261) 266 64.8 7.1e-11
>>CCDS4760.1 DMB gene_id:3109|Hs108|chr6 (263 aa)
initn: 1824 init1: 1824 opt: 1824 Z-score: 2069.7 bits: 390.6 E(32554): 5.8e-109
Smith-Waterman score: 1824; 99.6% identity (99.6% similar) in 263 aa overlap (1-263:1-263)
10 20 30 40 50 60
pF1KE2 MITFLPLLLGLSLGCTGAGGFVAHVESTCLLDDAGTPKDFTYCISFNKDLLTCWDPEENK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MITFLPLLLGLSLGCTGAGGFVAHVESTCLLDDAGTPKDFTYCISFNKDLLTCWDPEENK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MAPCEFGVLNSLANVLSQHLNQKDTLMQRLRNGLQNCATHTQPFWGSLTNRTRPPSVQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MAPCEFGVLNSLANVLSQHLNQKDTLMQRLRNGLQNCATHTQPFWGSLTNRTRPPSVQVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 KTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHSSAHKTAQPNGDWTYQTLSHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 KTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHSSAHKTAQPNGDWTYQTLSHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 ALTPSYGDTYTCVVEHIGAPEPILRDWTPGLSPMQTLKVSVSAVTLGLGLIIFSLGVISW
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
CCDS47 ALTPSYGDTYTCVVEHTGAPEPILRDWTPGLSPMQTLKVSVSAVTLGLGLIIFSLGVISW
190 200 210 220 230 240
250 260
pF1KE2 RRAGHSSYTPLPGSNYSEGWHIS
:::::::::::::::::::::::
CCDS47 RRAGHSSYTPLPGSNYSEGWHIS
250 260
>>CCDS4754.1 DOB gene_id:3112|Hs108|chr6 (273 aa)
initn: 246 init1: 143 opt: 286 Z-score: 331.1 bits: 69.0 E(32554): 4e-12
Smith-Waterman score: 286; 26.5% identity (59.1% similar) in 264 aa overlap (1-257:13-264)
10 20 30 40
pF1KE2 MITFLPLLLGLSLGCTGAGGFVAHVESTCLLDDAGTPK-DFTYCISFN
.... : ... : . :: .... : . . :: : .:. . ::
CCDS47 MGSGWVPWVVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTN-GTEKVQFVVRFIFN
10 20 30 40 50
50 60 70 80 90 100
pF1KE2 KDLLTCWDPEENKMAPCEFGVLNSLANVLSQHLNQKDTLMQRLRNGLQNCATHTQPFWGS
. . .: . . : .:..:.. ... :.. :..: :..... :. . .
CCDS47 LEEYVRFDSDVG-----MFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE2 LT-NRTRPPSVQV-AKTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHSSAHKT
.: .: : : : . ::. .. .: : : ::::... : : ::. . .. .
CCDS47 FTVGRKVQPEVTVYPERTPL-LHQHNLLHCSVTGFYPGDIKIKWFLNGQ---EERAGVMS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 AQP--NGDWTYQTLSHLALTPSYGDTYTCVVEHIGAPEPILRDWTPGLSPMQTLKVSVSA
. : :::::.::. : .:: : .:::.:.: . :. .: . : .. :. .
CCDS47 TGPIRNGDWTFQTVVMLEMTPELGHVYTCLVDHSSLLSPVSVEWR-AQSEYSWRKMLSGI
180 190 200 210 220
230 240 250 260
pF1KE2 VTLGLGLIIFSLGVISWRRAGHSSY--TPLPGSNYSEGWHIS
... ::::.. .:.. :: ...: : . :.. :
CCDS47 AAFLLGLIFLLVGIVIQLRA-QKGYVRTQMSGNEVSRAVLLPQSC
230 240 250 260 270
>>CCDS4765.1 DPB1 gene_id:3115|Hs108|chr6 (258 aa)
initn: 238 init1: 136 opt: 281 Z-score: 325.8 bits: 67.9 E(32554): 8e-12
Smith-Waterman score: 281; 30.9% identity (56.4% similar) in 181 aa overlap (65-243:73-250)
40 50 60 70 80 90
pF1KE2 GTPKDFTYCISFNKDLLTCWDPEENKMAPCEFGVLNSLANVLSQHLN-QKDTLMQRLRNG
:: ... :. ... : ::: : ..
CCDS47 ECYAFNGTQRFLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVP
50 60 70 80 90 100
100 110 120 130 140 150
pF1KE2 LQNCATHTQPFWGSLTNRTR-PPSVQVAKTTPFNTREPVMLACYVWGFYPAEVTITWRKN
. : :. . : .: . : : :.:. . .. .:.:.: :::. . . : :
CCDS47 DRMC-RHNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLN
110 120 130 140 150 160
160 170 180 190 200 210
pF1KE2 GKLVMPHSSAHKTAQPNGDWTYQTLSHLALTPSYGDTYTCVVEHIGAPEPILRDWTPGLS
:. . . . :::::.: : : .::. ::.::: ::: . :. .: . :
CCDS47 GQEETAGVVSTNLIR-NGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWK-AQS
170 180 190 200 210
220 230 240 250 260
pF1KE2 PMQTLKVSVSAVTLGLGLIIFSLGVISWRRAGHSSYTPLPGSNYSEGWHIS
:. ..: . ::::: ..:.. ::.
CCDS47 DSARSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA
220 230 240 250
>>CCDS59006.1 DQB1 gene_id:3119|Hs108|chr6 (269 aa)
initn: 228 init1: 156 opt: 276 Z-score: 319.8 bits: 66.9 E(32554): 1.7e-11
Smith-Waterman score: 276; 29.7% identity (58.2% similar) in 182 aa overlap (77-252:90-264)
50 60 70 80 90 100
pF1KE2 NKDLLTCWDPEENKMAPCEFGVLNSLANVLSQHLNQKDTLMQRLRNGLQNCATHTQP--F
... :.. ... : :.. :. :
CCDS59 TRYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAF
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE2 WGSLTNRTRPP-SVQVAKTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHSSAH
: : :..: ... ..: .: .. .:.: : :::... . : .: . . .:
CCDS59 RGILQRRVEPTVTISPSRTEALNHHN--LLVCSVTDFYPGQIKVRWFRNDQ----EETAG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 KTAQP---NGDWTYQTLSHLALTPSYGDTYTCVVEHIGAPEPILRDWTPGLSPMQTLKVS
.. : :::::.: : : .::. ::.::: ::: . :: .: :. :.
CCDS59 VVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQS-KML
180 190 200 210 220 230
230 240 250 260
pF1KE2 VSAVTLGLGLIIFSLGVISWRRAGHSSYTPLPGSNYSEGWHIS
.. . ::::...::.: .:. .. : :
CCDS59 SGVGGFVLGLIFLGLGLIIRQRSQKGPQGPPPAGLLH
240 250 260
>>CCDS78128.1 DQB2 gene_id:3120|Hs108|chr6 (264 aa)
initn: 253 init1: 155 opt: 275 Z-score: 318.8 bits: 66.7 E(32554): 1.9e-11
Smith-Waterman score: 275; 28.7% identity (52.1% similar) in 188 aa overlap (65-252:74-259)
40 50 60 70 80 90
pF1KE2 GTPKDFTYCISFNKDLLTCWDPEENKMAPCEFGVLNSLANVLSQHLNQKDTLMQRLRNGL
:: ... :. . . : :: : :.
CCDS78 YFTNGTERVRGVARYIYNREEYGRFDSDVGEFQAVTELGRSIEDWNNYKDFLEQERAAVD
50 60 70 80 90 100
100 110 120 130 140 150
pF1KE2 QNCATHTQPFWGSLTNRTRPPSVQVAKTTPFNTREPVMLACYVWGFYPAEVTITWRKNGK
. : . . . .: :.: .. . . .:.: : ::::.. . : .: .
CCDS78 KVCRHNYEAELRTTLQRQVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQ
110 120 130 140 150 160
160 170 180 190 200 210
pF1KE2 LVMPHSSAHKTAQPNGDWTYQTLSHLALTPSYGDTYTCVVEHIGAPEPILRDWTPGLSPM
. . . :::::.: : : .::. :: ::: ::: . :: .:
CCDS78 EETAGVVSTSLIR-NGDWTFQILVMLEITPQRGDIYTCQVEHPSLQSPITVEWRAQSESA
170 180 190 200 210 220
220 230 240 250 260
pF1KE2 QTLKVSVSAVTLGLGLIIFSLGVISWRRAGHSSYTPLPGSNYSEGWHIS
:. :. . . ::::...::.: .:. .. : :
CCDS78 QS-KMLSGIGGFVLGLIFLGLGLIIRHRGQKGPRGPPPAGLLH
230 240 250 260
>>CCDS47409.1 DRB1 gene_id:3123|Hs108|chr6 (266 aa)
initn: 215 init1: 125 opt: 273 Z-score: 316.5 bits: 66.2 E(32554): 2.6e-11
Smith-Waterman score: 273; 29.5% identity (56.8% similar) in 190 aa overlap (65-250:75-261)
40 50 60 70 80 90
pF1KE2 GTPKDFTYCISFNKDLLTCWDPEENKMAPCEFGVLNSLANVLSQHLNQKDTLMQRLRNGL
:: ... :. ... :.. .... : ..
CCDS47 HFFNGTERVRFLDRYFYNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAV
50 60 70 80 90 100
100 110 120 130 140 150
pF1KE2 QNCATHTQPFWGSLTNRTR-PPSVQV--AKTTPFNTREPVMLACYVWGFYPAEVTITWRK
.. :. :.: . : :.: : .:: :.. .. .:.: : ::::. . . :
CCDS47 DTYCRHNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHN--LLVCSVSGFYPGSIEVRWFL
110 120 130 140 150 160
160 170 180 190 200 210
pF1KE2 NGKLVMPHSSAHKTAQPNGDWTYQTLSHLALTPSYGDTYTCVVEHIGAPEPILRDWTPGL
::. . : :::::.::: : .: :..::: ::: .. :. .:
CCDS47 NGQEEKAGMVSTGLIQ-NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARS
170 180 190 200 210 220
220 230 240 250 260
pF1KE2 SPMQTLKVS-VSAVTLGLGLIIFSLGVISWRRAGHSSYTPLPGSNYSEGWHIS
:. .: :.. .::: .. .: . . :::. :
CCDS47 ESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS
230 240 250 260
>>CCDS43451.1 DQB1 gene_id:3119|Hs108|chr6 (261 aa)
initn: 228 init1: 156 opt: 266 Z-score: 308.7 bits: 64.8 E(32554): 7.1e-11
Smith-Waterman score: 266; 30.1% identity (59.0% similar) in 173 aa overlap (77-243:90-255)
50 60 70 80 90 100
pF1KE2 NKDLLTCWDPEENKMAPCEFGVLNSLANVLSQHLNQKDTLMQRLRNGLQNCATHTQP--F
... :.. ... : :.. :. :
CCDS43 TRYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAF
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE2 WGSLTNRTRPP-SVQVAKTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHSSAH
: : :..: ... ..: .: .. .:.: : :::... . : .: . . .:
CCDS43 RGILQRRVEPTVTISPSRTEALNHHN--LLVCSVTDFYPGQIKVRWFRNDQ----EETAG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 KTAQP---NGDWTYQTLSHLALTPSYGDTYTCVVEHIGAPEPILRDWTPGLSPMQTLKVS
.. : :::::.: : : .::. ::.::: ::: . :: .: :. :.
CCDS43 VVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQS-KML
180 190 200 210 220 230
230 240 250 260
pF1KE2 VSAVTLGLGLIIFSLGVISWRRAGHSSYTPLPGSNYSEGWHIS
.. . ::::...::.: .:.
CCDS43 SGVGGFVLGLIFLGLGLIIRQRSQKGLLH
240 250 260
263 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:27:13 2016 done: Mon Nov 7 00:27:13 2016
Total Scan time: 2.000 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]