Result of FASTA (omim) for
pFN21AE2229
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2229, 245 aa
1>>>pF1KE2229 245 - 245 aa - 245 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8269+/-0.000285; mu= 18.3603+/- 0.018
mean_var=81.2090+/-16.203, 0's: 0 Z-trim(119.7): 25 B-trim: 437 in 1/52
Lambda= 0.142322
statistics sampled from 34038 (34065) to 34038 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.399), width: 16
Scan time: 7.570
The best scores are: opt bits E(85289)
NP_689772 (OMIM: 612546) Williams-Beuren syndrome ( 245) 1673 352.3 4.5e-97
XP_016867266 (OMIM: 612546) PREDICTED: Williams-Be ( 271) 1093 233.3 3.4e-61
XP_016867267 (OMIM: 612546) PREDICTED: Williams-Be ( 271) 1093 233.3 3.4e-61
XP_011514081 (OMIM: 615733) PREDICTED: probable 18 ( 248) 149 39.4 0.0071
NP_059998 (OMIM: 615733) probable 18S rRNA (guanin ( 281) 149 39.5 0.0077
NP_001189489 (OMIM: 615733) probable 18S rRNA (gua ( 298) 149 39.5 0.0081
>>NP_689772 (OMIM: 612546) Williams-Beuren syndrome chro (245 aa)
initn: 1673 init1: 1673 opt: 1673 Z-score: 1863.8 bits: 352.3 E(85289): 4.5e-97
Smith-Waterman score: 1673; 98.8% identity (99.2% similar) in 245 aa overlap (1-245:1-245)
10 20 30 40 50 60
pF1KE2 MAQEEGGSLPEVRARVRAAHGIPDLAQKLHFYDRWAPDYDQDVATLLYRAPRLAVDCLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MAQEEGGSLPEVRARVRAAHGIPDLAQKLHFYDRWAPDYDQDVATLLYRAPRLAVDCLTQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ALPGPPHSALILDVACGTGLVAAELRAPGFLQLHGVDGSPGMLEQARAPGLYQRLSLCTL
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
NP_689 ALPGPPHSALILDVACGTGLVAAELRAPGFLQLHGVDGSPGMLEQAQAPGLYQRLSLCTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GQEPLPSPEGTFDAVLIVGALSDGQVPCNAIPELHVTKPGGLVCLTTRTNWSNLQYKEAL
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
NP_689 GQEPLPSPEGTFDAVLIVGALSDGQVPCNAIPELHVTKPGGLVCLTTRTNSSNLQYKEAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EATLDRLEQAGMWEGLVAWPVDRLWTAGSWLPPSWWWYPASLPRMASSPALSTCTESGRR
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_689 EATLDRLEQAGMWEGLVAWPVDRLWTAGSWLPPSWRWYPASLPRMASSPALSTCTESGRR
190 200 210 220 230 240
pF1KE2 PRLRK
:::::
NP_689 PRLRK
>>XP_016867266 (OMIM: 612546) PREDICTED: Williams-Beuren (271 aa)
initn: 1144 init1: 1093 opt: 1093 Z-score: 1219.7 bits: 233.3 E(85289): 3.4e-61
Smith-Waterman score: 1611; 89.3% identity (89.7% similar) in 271 aa overlap (1-245:1-271)
10 20 30 40 50 60
pF1KE2 MAQEEGGSLPEVRARVRAAHGIPDLAQKLHFYDRWAPDYDQDVATLLYRAPRLAVDCLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQEEGGSLPEVRARVRAAHGIPDLAQKLHFYDRWAPDYDQDVATLLYRAPRLAVDCLTQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ALPGPPHSALILDVACGTGLVAAELRAPGFLQLHGVDGSPGMLEQARAPGLYQRLSLCTL
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
XP_016 ALPGPPHSALILDVACGTGLVAAELRAPGFLQLHGVDGSPGMLEQAQAPGLYQRLSLCTL
70 80 90 100 110 120
130 140 150 160
pF1KE2 GQEPLPSPEGTFDAVLIVGALSDGQVPCNAIPELHVTKPG--------------------
::::::::::::::::::::::::::::::::::::::::
XP_016 GQEPLPSPEGTFDAVLIVGALSDGQVPCNAIPELHVTKPGTTIPSRDGPGLWLLPLPHLT
130 140 150 160 170 180
170 180 190 200 210
pF1KE2 ------GLVCLTTRTNWSNLQYKEALEATLDRLEQAGMWEGLVAWPVDRLWTAGSWLPPS
:::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_016 YPSPPGGLVCLTTRTNSSNLQYKEALEATLDRLEQAGMWEGLVAWPVDRLWTAGSWLPPS
190 200 210 220 230 240
220 230 240
pF1KE2 WWWYPASLPRMASSPALSTCTESGRRPRLRK
: :::::::::::::::::::::::::::::
XP_016 WRWYPASLPRMASSPALSTCTESGRRPRLRK
250 260 270
>>XP_016867267 (OMIM: 612546) PREDICTED: Williams-Beuren (271 aa)
initn: 1144 init1: 1093 opt: 1093 Z-score: 1219.7 bits: 233.3 E(85289): 3.4e-61
Smith-Waterman score: 1611; 89.3% identity (89.7% similar) in 271 aa overlap (1-245:1-271)
10 20 30 40 50 60
pF1KE2 MAQEEGGSLPEVRARVRAAHGIPDLAQKLHFYDRWAPDYDQDVATLLYRAPRLAVDCLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQEEGGSLPEVRARVRAAHGIPDLAQKLHFYDRWAPDYDQDVATLLYRAPRLAVDCLTQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ALPGPPHSALILDVACGTGLVAAELRAPGFLQLHGVDGSPGMLEQARAPGLYQRLSLCTL
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
XP_016 ALPGPPHSALILDVACGTGLVAAELRAPGFLQLHGVDGSPGMLEQAQAPGLYQRLSLCTL
70 80 90 100 110 120
130 140 150 160
pF1KE2 GQEPLPSPEGTFDAVLIVGALSDGQVPCNAIPELHVTKPG--------------------
::::::::::::::::::::::::::::::::::::::::
XP_016 GQEPLPSPEGTFDAVLIVGALSDGQVPCNAIPELHVTKPGTTIPSRDGPGLWLLPLPHLT
130 140 150 160 170 180
170 180 190 200 210
pF1KE2 ------GLVCLTTRTNWSNLQYKEALEATLDRLEQAGMWEGLVAWPVDRLWTAGSWLPPS
:::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_016 YPSPPGGLVCLTTRTNSSNLQYKEALEATLDRLEQAGMWEGLVAWPVDRLWTAGSWLPPS
190 200 210 220 230 240
220 230 240
pF1KE2 WWWYPASLPRMASSPALSTCTESGRRPRLRK
: :::::::::::::::::::::::::::::
XP_016 WRWYPASLPRMASSPALSTCTESGRRPRLRK
250 260 270
>>XP_011514081 (OMIM: 615733) PREDICTED: probable 18S rR (248 aa)
initn: 128 init1: 64 opt: 149 Z-score: 172.6 bits: 39.4 E(85289): 0.0071
Smith-Waterman score: 149; 31.7% identity (54.0% similar) in 139 aa overlap (13-150:4-131)
10 20 30 40 50 60
pF1KE2 MAQEEGGSLPEVRARVRAAHGIPDLAQKLHFYDRWAPDYDQDVATLLYRAPRLAVDCLTQ
:.: : :: : .: . . : : .. . .. :.: : .
XP_011 MASRGR-RPEHGGPP---ELFYDETEARKYVRN-SRMIDIQTRMAGRAL-E
10 20 30 40
70 80 90 100 110
pF1KE2 ALPGPPHSA-LILDVACGTGLVAAELRAPGFLQLHGVDGSPGMLEQARAPGLYQRLSLCT
: : .. .::..::::: .. : : . :.: ::.::..: . : :
XP_011 LLYLPENKPCYLLDIGCGTGLSGSYLSDEGHYWV-GLDISPAMLDEAVDREIEGDLLLGD
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 LGQEPLPSPEGTFDAVLIVGALSDGQVPCNAIPELHVTKPGGLVCLTTRTNWSNLQYKEA
.:: .: ::::. . ..:. : :::
XP_011 MGQ-GIPFKPGTFDGCISISAV---QWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAV
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 LEATLDRLEQAGMWEGLVAWPVDRLWTAGSWLPPSWWWYPASLPRMASSPALSTCTESGR
XP_011 LQLYPENSEQLELITTQATKAGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEVPIKDV
170 180 190 200 210 220
>>NP_059998 (OMIM: 615733) probable 18S rRNA (guanine-N( (281 aa)
initn: 128 init1: 64 opt: 149 Z-score: 171.9 bits: 39.5 E(85289): 0.0077
Smith-Waterman score: 149; 31.7% identity (54.0% similar) in 139 aa overlap (13-150:4-131)
10 20 30 40 50 60
pF1KE2 MAQEEGGSLPEVRARVRAAHGIPDLAQKLHFYDRWAPDYDQDVATLLYRAPRLAVDCLTQ
:.: : :: : .: . . : : .. . .. :.: : .
NP_059 MASRGR-RPEHGGPP---ELFYDETEARKYVRN-SRMIDIQTRMAGRAL-E
10 20 30 40
70 80 90 100 110
pF1KE2 ALPGPPHSA-LILDVACGTGLVAAELRAPGFLQLHGVDGSPGMLEQARAPGLYQRLSLCT
: : .. .::..::::: .. : : . :.: ::.::..: . : :
NP_059 LLYLPENKPCYLLDIGCGTGLSGSYLSDEGHYWV-GLDISPAMLDEAVDREIEGDLLLGD
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 LGQEPLPSPEGTFDAVLIVGALSDGQVPCNAIPELHVTKPGGLVCLTTRTNWSNLQYKEA
.:: .: ::::. . ..:. : :::
NP_059 MGQ-GIPFKPGTFDGCISISAV---QWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAV
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 LEATLDRLEQAGMWEGLVAWPVDRLWTAGSWLPPSWWWYPASLPRMASSPALSTCTESGR
NP_059 LQLYPENSEQLELITTQATKAGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQ
170 180 190 200 210 220
>>NP_001189489 (OMIM: 615733) probable 18S rRNA (guanine (298 aa)
initn: 128 init1: 64 opt: 149 Z-score: 171.6 bits: 39.5 E(85289): 0.0081
Smith-Waterman score: 149; 31.7% identity (54.0% similar) in 139 aa overlap (13-150:4-131)
10 20 30 40 50 60
pF1KE2 MAQEEGGSLPEVRARVRAAHGIPDLAQKLHFYDRWAPDYDQDVATLLYRAPRLAVDCLTQ
:.: : :: : .: . . : : .. . .. :.: : .
NP_001 MASRGR-RPEHGGPP---ELFYDETEARKYVRN-SRMIDIQTRMAGRAL-E
10 20 30 40
70 80 90 100 110
pF1KE2 ALPGPPHSA-LILDVACGTGLVAAELRAPGFLQLHGVDGSPGMLEQARAPGLYQRLSLCT
: : .. .::..::::: .. : : . :.: ::.::..: . : :
NP_001 LLYLPENKPCYLLDIGCGTGLSGSYLSDEGHYWV-GLDISPAMLDEAVDREIEGDLLLGD
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 LGQEPLPSPEGTFDAVLIVGALSDGQVPCNAIPELHVTKPGGLVCLTTRTNWSNLQYKEA
.:: .: ::::. . ..:. : :::
NP_001 MGQ-GIPFKPGTFDGCISISAV---QWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAV
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 LEATLDRLEQAGMWEGLVAWPVDRLWTAGSWLPPSWWWYPASLPRMASSPALSTCTESGR
NP_001 LQLYPENSEQLELITTQATKAGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQ
170 180 190 200 210 220
245 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:16:08 2016 done: Mon Nov 7 00:16:09 2016
Total Scan time: 7.570 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]