Result of FASTA (omim) for
pFN21AE2222
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2222, 246 aa
1>>>pF1KE2222 246 - 246 aa - 246 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1400+/-0.000326; mu= 15.7183+/- 0.020
mean_var=70.8518+/-14.870, 0's: 0 Z-trim(115.9): 18 B-trim: 1132 in 1/53
Lambda= 0.152370
statistics sampled from 26644 (26653) to 26644 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.313), width: 16
Scan time: 6.840
The best scores are: opt bits E(85289)
NP_037525 (OMIM: 606906) rRNA methyltransferase 2, ( 246) 1657 373.0 2.7e-103
NP_803188 (OMIM: 300499,309549) putative tRNA (cyt ( 327) 397 96.1 8.2e-20
XP_005272652 (OMIM: 300499,309549) PREDICTED: puta ( 327) 397 96.1 8.2e-20
NP_036412 (OMIM: 300499,309549) putative tRNA (cyt ( 329) 397 96.1 8.2e-20
XP_016884871 (OMIM: 300499,309549) PREDICTED: puta ( 335) 397 96.1 8.4e-20
XP_011542197 (OMIM: 300499,309549) PREDICTED: puta ( 335) 397 96.1 8.4e-20
XP_011542196 (OMIM: 300499,309549) PREDICTED: puta ( 337) 397 96.1 8.4e-20
XP_011542195 (OMIM: 300499,309549) PREDICTED: puta ( 337) 397 96.1 8.4e-20
>>NP_037525 (OMIM: 606906) rRNA methyltransferase 2, mit (246 aa)
initn: 1657 init1: 1657 opt: 1657 Z-score: 1975.3 bits: 373.0 E(85289): 2.7e-103
Smith-Waterman score: 1657; 100.0% identity (100.0% similar) in 246 aa overlap (1-246:1-246)
10 20 30 40 50 60
pF1KE2 MAGYLKLVCVSFQRQGFHTVGSRCKNRTGAEHLWLTRHLRDPFVKAAKVESYRCRSAFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MAGYLKLVCVSFQRQGFHTVGSRCKNRTGAEHLWLTRHLRDPFVKAAKVESYRCRSAFKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 LEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GATFLCPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 GATFLCPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TPDILQPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 TPDILQPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGR
190 200 210 220 230 240
pF1KE2 KGTVKQ
::::::
NP_037 KGTVKQ
>>NP_803188 (OMIM: 300499,309549) putative tRNA (cytidin (327 aa)
initn: 363 init1: 178 opt: 397 Z-score: 476.7 bits: 96.1 E(85289): 8.2e-20
Smith-Waterman score: 397; 33.5% identity (65.6% similar) in 209 aa overlap (36-244:5-206)
10 20 30 40 50 60
pF1KE2 KLVCVSFQRQGFHTVGSRCKNRTGAEHLWLTRHLRDPFVKAAKVESYRCRSAFKLLEVNE
.. :: . . :: ...: :::::::....
NP_803 MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDK
10 20 30
70 80 90 100 110 120
pF1KE2 RHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLEGATFL
. :... :..: ::::.:::: ::... :. : :..::: . :: :.. .
NP_803 EFQLFQGVTRAVDLCAAPGSWSQVLSQKIGGQGS------GHVVAVDLQAMAPLPGVVQI
40 50 60 70 80
130 140 150 160 170 180
pF1KE2 CPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSVTPDIL
.:.:. :...:.. . : ::... : ::..::..:.:. .: :. :... .:
NP_803 -QGDITQLSTAKEIIQHFKGCPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVL
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 QPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGRKGTVK
.::: :. : . : . : .: :..: ::..::. : :.. . : .: .
NP_803 KPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAKPRSSRNSSIEAFAVCQGYDPPEGFIP
150 160 170 180 190 200
pF1KE2 Q
NP_803 DLSKPLLDHSYDFNQLDGPTRIIVPFVTCGDLSSYDSDRSYPLDLEGGSEYKYTPPTQPP
210 220 230 240 250 260
>>XP_005272652 (OMIM: 300499,309549) PREDICTED: putative (327 aa)
initn: 363 init1: 178 opt: 397 Z-score: 476.7 bits: 96.1 E(85289): 8.2e-20
Smith-Waterman score: 397; 33.5% identity (65.6% similar) in 209 aa overlap (36-244:5-206)
10 20 30 40 50 60
pF1KE2 KLVCVSFQRQGFHTVGSRCKNRTGAEHLWLTRHLRDPFVKAAKVESYRCRSAFKLLEVNE
.. :: . . :: ...: :::::::....
XP_005 MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDK
10 20 30
70 80 90 100 110 120
pF1KE2 RHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLEGATFL
. :... :..: ::::.:::: ::... :. : :..::: . :: :.. .
XP_005 EFQLFQGVTRAVDLCAAPGSWSQVLSQKIGGQGS------GHVVAVDLQAMAPLPGVVQI
40 50 60 70 80
130 140 150 160 170 180
pF1KE2 CPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSVTPDIL
.:.:. :...:.. . : ::... : ::..::..:.:. .: :. :... .:
XP_005 -QGDITQLSTAKEIIQHFKGCPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVL
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 QPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGRKGTVK
.::: :. : . : . : .: :..: ::..::. : :.. . : .: .
XP_005 KPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAKPRSSRNSSIEAFAVCQGYDPPEGFIP
150 160 170 180 190 200
pF1KE2 Q
XP_005 DLSKPLLDHSYDFNQLDGPTRIIVPFVTCGDLSSYDSDRSYPLDLEGGSEYKYTPPTQPP
210 220 230 240 250 260
>>NP_036412 (OMIM: 300499,309549) putative tRNA (cytidin (329 aa)
initn: 363 init1: 178 opt: 397 Z-score: 476.6 bits: 96.1 E(85289): 8.2e-20
Smith-Waterman score: 397; 33.5% identity (65.6% similar) in 209 aa overlap (36-244:5-206)
10 20 30 40 50 60
pF1KE2 KLVCVSFQRQGFHTVGSRCKNRTGAEHLWLTRHLRDPFVKAAKVESYRCRSAFKLLEVNE
.. :: . . :: ...: :::::::....
NP_036 MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDK
10 20 30
70 80 90 100 110 120
pF1KE2 RHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLEGATFL
. :... :..: ::::.:::: ::... :. : :..::: . :: :.. .
NP_036 EFQLFQGVTRAVDLCAAPGSWSQVLSQKIGGQGS------GHVVAVDLQAMAPLPGVVQI
40 50 60 70 80
130 140 150 160 170 180
pF1KE2 CPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSVTPDIL
.:.:. :...:.. . : ::... : ::..::..:.:. .: :. :... .:
NP_036 -QGDITQLSTAKEIIQHFKGCPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVL
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 QPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGRKGTVK
.::: :. : . : . : .: :..: ::..::. : :.. . : .: .
NP_036 KPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAKPRSSRNSSIEAFAVCQGYDPPEGFIP
150 160 170 180 190 200
pF1KE2 Q
NP_036 DLSKPLLDHSYDPDFNQLDGPTRIIVPFVTCGDLSSYDSDRSYPLDLEGGSEYKYTPPTQ
210 220 230 240 250 260
>>XP_016884871 (OMIM: 300499,309549) PREDICTED: putative (335 aa)
initn: 363 init1: 178 opt: 397 Z-score: 476.5 bits: 96.1 E(85289): 8.4e-20
Smith-Waterman score: 397; 33.5% identity (65.6% similar) in 209 aa overlap (36-244:5-206)
10 20 30 40 50 60
pF1KE2 KLVCVSFQRQGFHTVGSRCKNRTGAEHLWLTRHLRDPFVKAAKVESYRCRSAFKLLEVNE
.. :: . . :: ...: :::::::....
XP_016 MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDK
10 20 30
70 80 90 100 110 120
pF1KE2 RHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLEGATFL
. :... :..: ::::.:::: ::... :. : :..::: . :: :.. .
XP_016 EFQLFQGVTRAVDLCAAPGSWSQVLSQKIGGQGS------GHVVAVDLQAMAPLPGVVQI
40 50 60 70 80
130 140 150 160 170 180
pF1KE2 CPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSVTPDIL
.:.:. :...:.. . : ::... : ::..::..:.:. .: :. :... .:
XP_016 -QGDITQLSTAKEIIQHFKGCPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVL
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 QPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGRKGTVK
.::: :. : . : . : .: :..: ::..::. : :.. . : .: .
XP_016 KPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAKPRSSRNSSIEAFAVCQGYDPPEGFIP
150 160 170 180 190 200
pF1KE2 Q
XP_016 DLSKPLLDHSYDFNQLDGPTRIIVPFVTCGDLSSYDSDRSYPLDLEGGSEYKYTPPTQPP
210 220 230 240 250 260
>>XP_011542197 (OMIM: 300499,309549) PREDICTED: putative (335 aa)
initn: 363 init1: 178 opt: 397 Z-score: 476.5 bits: 96.1 E(85289): 8.4e-20
Smith-Waterman score: 397; 33.5% identity (65.6% similar) in 209 aa overlap (36-244:5-206)
10 20 30 40 50 60
pF1KE2 KLVCVSFQRQGFHTVGSRCKNRTGAEHLWLTRHLRDPFVKAAKVESYRCRSAFKLLEVNE
.. :: . . :: ...: :::::::....
XP_011 MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDK
10 20 30
70 80 90 100 110 120
pF1KE2 RHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLEGATFL
. :... :..: ::::.:::: ::... :. : :..::: . :: :.. .
XP_011 EFQLFQGVTRAVDLCAAPGSWSQVLSQKIGGQGS------GHVVAVDLQAMAPLPGVVQI
40 50 60 70 80
130 140 150 160 170 180
pF1KE2 CPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSVTPDIL
.:.:. :...:.. . : ::... : ::..::..:.:. .: :. :... .:
XP_011 -QGDITQLSTAKEIIQHFKGCPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVL
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 QPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGRKGTVK
.::: :. : . : . : .: :..: ::..::. : :.. . : .: .
XP_011 KPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAKPRSSRNSSIEAFAVCQGYDPPEGFIP
150 160 170 180 190 200
pF1KE2 Q
XP_011 DLSKPLLDHSYDFNQLDGPTRIIVPFVTCGDLSSYDSDRSYPLDLEGGSEYKYTPPTQPP
210 220 230 240 250 260
>>XP_011542196 (OMIM: 300499,309549) PREDICTED: putative (337 aa)
initn: 363 init1: 178 opt: 397 Z-score: 476.5 bits: 96.1 E(85289): 8.4e-20
Smith-Waterman score: 397; 33.5% identity (65.6% similar) in 209 aa overlap (36-244:5-206)
10 20 30 40 50 60
pF1KE2 KLVCVSFQRQGFHTVGSRCKNRTGAEHLWLTRHLRDPFVKAAKVESYRCRSAFKLLEVNE
.. :: . . :: ...: :::::::....
XP_011 MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDK
10 20 30
70 80 90 100 110 120
pF1KE2 RHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLEGATFL
. :... :..: ::::.:::: ::... :. : :..::: . :: :.. .
XP_011 EFQLFQGVTRAVDLCAAPGSWSQVLSQKIGGQGS------GHVVAVDLQAMAPLPGVVQI
40 50 60 70 80
130 140 150 160 170 180
pF1KE2 CPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSVTPDIL
.:.:. :...:.. . : ::... : ::..::..:.:. .: :. :... .:
XP_011 -QGDITQLSTAKEIIQHFKGCPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVL
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 QPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGRKGTVK
.::: :. : . : . : .: :..: ::..::. : :.. . : .: .
XP_011 KPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAKPRSSRNSSIEAFAVCQGYDPPEGFIP
150 160 170 180 190 200
pF1KE2 Q
XP_011 DLSKPLLDHSYDPDFNQLDGPTRIIVPFVTCGDLSSYDSDRSYPLDLEGGSEYKYTPPTQ
210 220 230 240 250 260
>>XP_011542195 (OMIM: 300499,309549) PREDICTED: putative (337 aa)
initn: 363 init1: 178 opt: 397 Z-score: 476.5 bits: 96.1 E(85289): 8.4e-20
Smith-Waterman score: 397; 33.5% identity (65.6% similar) in 209 aa overlap (36-244:5-206)
10 20 30 40 50 60
pF1KE2 KLVCVSFQRQGFHTVGSRCKNRTGAEHLWLTRHLRDPFVKAAKVESYRCRSAFKLLEVNE
.. :: . . :: ...: :::::::....
XP_011 MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDK
10 20 30
70 80 90 100 110 120
pF1KE2 RHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLEGATFL
. :... :..: ::::.:::: ::... :. : :..::: . :: :.. .
XP_011 EFQLFQGVTRAVDLCAAPGSWSQVLSQKIGGQGS------GHVVAVDLQAMAPLPGVVQI
40 50 60 70 80
130 140 150 160 170 180
pF1KE2 CPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSVTPDIL
.:.:. :...:.. . : ::... : ::..::..:.:. .: :. :... .:
XP_011 -QGDITQLSTAKEIIQHFKGCPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVL
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 QPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGRKGTVK
.::: :. : . : . : .: :..: ::..::. : :.. . : .: .
XP_011 KPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAKPRSSRNSSIEAFAVCQGYDPPEGFIP
150 160 170 180 190 200
pF1KE2 Q
XP_011 DLSKPLLDHSYDPDFNQLDGPTRIIVPFVTCGDLSSYDSDRSYPLDLEGGSEYKYTPPTQ
210 220 230 240 250 260
246 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 15:56:45 2016 done: Mon Nov 7 15:56:46 2016
Total Scan time: 6.840 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]