Result of FASTA (ccds) for
pFN21AE2220
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2220, 174 aa
1>>>pF1KE2220 174 - 174 aa - 174 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4148+/-0.000689; mu= 11.7144+/- 0.041
mean_var=62.9792+/-12.601, 0's: 0 Z-trim(109.6): 17 B-trim: 54 in 1/50
Lambda= 0.161613
statistics sampled from 10985 (11000) to 10985 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.716), E-opt: 0.2 (0.338), width: 16
Scan time: 1.840
The best scores are: opt bits E(32554)
CCDS2379.1 CRYGC gene_id:1420|Hs108|chr2 ( 174) 1251 299.7 5.9e-82
CCDS2380.1 CRYGB gene_id:1419|Hs108|chr2 ( 175) 1020 245.9 9.6e-66
CCDS33367.1 CRYGA gene_id:1418|Hs108|chr2 ( 174) 972 234.7 2.2e-62
CCDS2378.1 CRYGD gene_id:1421|Hs108|chr2 ( 174) 920 222.5 1e-58
CCDS3275.1 CRYGS gene_id:1427|Hs108|chr3 ( 178) 698 170.8 3.9e-43
CCDS13830.1 CRYBB3 gene_id:1417|Hs108|chr22 ( 211) 400 101.3 3.7e-22
CCDS13831.1 CRYBB2 gene_id:1415|Hs108|chr22 ( 205) 388 98.5 2.5e-21
CCDS13840.1 CRYBB1 gene_id:1414|Hs108|chr22 ( 252) 382 97.2 8e-21
CCDS11249.1 CRYBA1 gene_id:1411|Hs108|chr17 ( 215) 371 94.6 4.1e-20
CCDS13841.1 CRYBA4 gene_id:1413|Hs108|chr22 ( 196) 351 89.9 9.6e-19
CCDS2429.1 CRYBA2 gene_id:1412|Hs108|chr2 ( 197) 330 85.0 2.9e-17
CCDS5926.1 CRYGN gene_id:155051|Hs108|chr7 ( 182) 321 82.9 1.1e-16
CCDS34506.1 AIM1 gene_id:202|Hs108|chr6 (1723) 292 76.5 8.9e-14
CCDS78289.1 CRYGN gene_id:155051|Hs108|chr7 ( 125) 275 72.1 1.4e-13
>>CCDS2379.1 CRYGC gene_id:1420|Hs108|chr2 (174 aa)
initn: 1251 init1: 1251 opt: 1251 Z-score: 1584.9 bits: 299.7 E(32554): 5.9e-82
Smith-Waterman score: 1251; 100.0% identity (100.0% similar) in 174 aa overlap (1-174:1-174)
10 20 30 40 50 60
pF1KE2 MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GEYPDYQQWMGLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 GEYPDYQQWMGLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 IRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 IRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
130 140 150 160 170
>>CCDS2380.1 CRYGB gene_id:1419|Hs108|chr2 (175 aa)
initn: 592 init1: 592 opt: 1020 Z-score: 1293.7 bits: 245.9 E(32554): 9.6e-66
Smith-Waterman score: 1020; 78.9% identity (93.1% similar) in 175 aa overlap (1-174:1-175)
10 20 30 40 50 60
pF1KE2 MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR
:::::::::::::::::: :::::::::::::::::::::::::.::::::::.::.:::
CCDS23 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
10 20 30 40 50 60
70 80 90 100 110
pF1KE2 GEYPDYQQWMGLSDSIRSCCLIP-QTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLS
::::::::::::::::::::::: .. ..:...:.:.. .: : ::..:: :.::::::.
CCDS23 GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCISVQDRFHLT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 EIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
::.::.:::: :.:::.:::::::::::: :::: :::: .::.::::::.:::
CCDS23 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
130 140 150 160 170
>>CCDS33367.1 CRYGA gene_id:1418|Hs108|chr2 (174 aa)
initn: 972 init1: 972 opt: 972 Z-score: 1233.3 bits: 234.7 E(32554): 2.2e-62
Smith-Waterman score: 972; 74.7% identity (90.2% similar) in 174 aa overlap (1-174:1-174)
10 20 30 40 50 60
pF1KE2 MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR
:::::::::: :::: :. .:::::. ::::::::::.::::::::::::::.::.:::
CCDS33 MGKITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GEYPDYQQWMGLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE
:.:::::.:::::::..:: .::.: ::.::::::.:..::: ::..:: . . :.: :
CCDS33 GKYPDYQHWMGLSDSVQSCRIIPHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPE
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 IRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
: :::::::::::::.:::::::::::: .::: .:::. :::.::::::.:::
CCDS33 IYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTDLY
130 140 150 160 170
>>CCDS2378.1 CRYGD gene_id:1421|Hs108|chr2 (174 aa)
initn: 1060 init1: 920 opt: 920 Z-score: 1167.8 bits: 222.5 E(32554): 1e-58
Smith-Waterman score: 920; 71.7% identity (90.2% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KE2 MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR
:::::.::::.:::: :: ..: ::::::.::::: ::.::::::::.:::.: ::.:::
CCDS23 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GEYPDYQQWMGLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE
:.: :.:::::::::.::: :::.. :::.:::::::..: :.:..::: .::::...:
CCDS23 GDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNE
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 IRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
:.::.:::: :::::: ::::::::: : .::: ::::: .:..::::::.:.
CCDS23 IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVIDFS
130 140 150 160 170
>>CCDS3275.1 CRYGS gene_id:1427|Hs108|chr3 (178 aa)
initn: 649 init1: 367 opt: 698 Z-score: 887.9 bits: 170.8 E(32554): 3.9e-43
Smith-Waterman score: 698; 53.5% identity (79.7% similar) in 172 aa overlap (3-172:7-178)
10 20 30 40 50
pF1KE2 MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQY
:::::::. :::: :. :: ... :.::::::.::.: : .:::::. : .:
CCDS32 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 LLRRGEYPDYQQWMGLSDSIRSCCLI--PQTVSHRLRLYEREDHKGLMMELSEDCPSIQD
.: .::::.::.::::.: . :: . :. .......:. : .: :.: .::::::..
CCDS32 ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 RFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
.::. ::.: .:::: :..::::::::::::: .:::. :::: . . :.::.:.
CCDS32 QFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
130 140 150 160 170
>>CCDS13830.1 CRYBB3 gene_id:1417|Hs108|chr22 (211 aa)
initn: 347 init1: 168 opt: 400 Z-score: 511.2 bits: 101.3 E(32554): 3.7e-22
Smith-Waterman score: 400; 34.9% identity (68.0% similar) in 175 aa overlap (3-172:25-199)
10 20 30
pF1KE2 MGKITFYEDRAFQGRSYETTTDCPNL-QPYFSRCNSIR
:. .:: . :::. : ...::.: . . . .::.
CCDS13 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE2 VESGCWMLYERPNYQGQQYLLRRGEYPDYQQWMGLSDSIRSCCLIPQTVS---HRLRLYE
:::: :. .: ..:.:..:..:.:: .. : . :: : : ... :.:.:.:
CCDS13 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFE
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE2 REDHKGLMMEL-SEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRR
.: ::. ..: ::. . ... :.....: :: ::.:.::::::... :::.
CCDS13 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
130 140 150 160 170 180
160 170
pF1KE2 CQDWGAMDAKAGSLRRVVDLY
..: : . . :.::. :
CCDS13 WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
190 200 210
>>CCDS13831.1 CRYBB2 gene_id:1415|Hs108|chr22 (205 aa)
initn: 399 init1: 164 opt: 388 Z-score: 496.3 bits: 98.5 E(32554): 2.5e-21
Smith-Waterman score: 388; 36.0% identity (66.9% similar) in 178 aa overlap (3-173:18-193)
10 20 30 40
pF1KE2 MGKITFYEDRAFQGRSYETTTDCPNLQPY-FSRCNSIRVESGCWM
:: ..:.. :::.:.: . ::::. . .:. :..: :.
CCDS13 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
10 20 30 40 50 60
50 60 70 80 90
pF1KE2 LYERPNYQGQQYLLRRGEYPDYQQWMGL--SDSIRSCCLIPQTVS---HRLRLYEREDHK
::. : .:.:.....:::: ...: . .::. : : : :. :.. ::: .
CCDS13 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSS--LRPIKVDSQEHKIILYENPNFT
70 80 90 100 110
100 110 120 130 140 150
pF1KE2 GLMMEL-SEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWG
: ::. ..: ::.. . . .. :..: : :: :. :.::: ::::. .:. .:.:
CCDS13 GKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFG
120 130 140 150 160 170
160 170
pF1KE2 AMDAKAGSLRRVVDLY
: .. :.::. :.
CCDS13 APHPQVQSVRRIRDMQWHQRGAFHPSN
180 190 200
>>CCDS13840.1 CRYBB1 gene_id:1414|Hs108|chr22 (252 aa)
initn: 350 init1: 174 opt: 382 Z-score: 487.3 bits: 97.2 E(32554): 8e-21
Smith-Waterman score: 382; 34.9% identity (64.6% similar) in 175 aa overlap (3-172:60-234)
10 20 30
pF1KE2 MGKITFYEDRAFQGRSYETTTDCPNLQPY-FS
... .: . :::: : . .: :: :.
CCDS13 GTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADRGFD
30 40 50 60 70 80
40 50 60 70 80
pF1KE2 RCNSIRVESGCWMLYERPNYQGQQYLLRRGEYPDYQQWMGLSDSIRSCCLIPQTVS---H
: :: : .: :. .:. :..:....:..:::: .. : . : : . : .. :
CCDS13 RVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDAQEH
90 100 110 120 130 140
90 100 110 120 130 140
pF1KE2 RLRLYEREDHKGLMMELS-EDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLR
.. :.: . :: .:.. .: ::. ... :..: : :: :. :.::: ::::.
CCDS13 KISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQYLLE
150 160 170 180 190 200
150 160 170
pF1KE2 PQEYRRCQDWGAMDAKAGSLRRVVDLY
: ..:. ..:::.. . ::::. :
CCDS13 PGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
210 220 230 240 250
>>CCDS11249.1 CRYBA1 gene_id:1411|Hs108|chr17 (215 aa)
initn: 288 init1: 143 opt: 371 Z-score: 474.5 bits: 94.6 E(32554): 4.1e-20
Smith-Waterman score: 398; 35.5% identity (66.1% similar) in 183 aa overlap (3-170:32-213)
10 20 30
pF1KE2 MGKITFYEDRAFQGRSYETTTDCPNLQPY-FS
:::.:... :::. .: :..:::.. :.
CCDS11 ETQAEQQELETLPTTKMAQTNPTPGSLGPWKITIYDQENFQGKRMEFTSSCPNVSERSFD
10 20 30 40 50 60
40 50 60 70 80
pF1KE2 RCNSIRVESGCWMLYERPNYQGQQYLLRRGEYPDYQQWMGLSD-------SIRSCCLIPQ
:..:::: :. ::. .. :::..:.::::: .. : : . :.: : .
CCDS11 NVRSLKVESGAWIGYEHTSFCGQQFILERGEYPRWDAWSGSNAYHIERLMSFRPICSANH
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE2 TVSHRLRLYEREDHKGLMMELSEDCPSIQDR-FHLSEIRSLHVLEGCWVLYELPNYRGRQ
: .. ..:.:. : . :.:.: ::.: . .:. :... : :: :. :.::: :
CCDS11 KES-KMTIFEKENFIGRQWEISDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGYQ
130 140 150 160 170 180
150 160 170
pF1KE2 YLLRPQ----EYRRCQDWG--AMDAKAGSLRRVVDLY
:.:. . .:.. ..:: :. .. :.::.
CCDS11 YILECDHHGGDYKHWREWGSHAQTSQIQSIRRIQQ
190 200 210
>>CCDS13841.1 CRYBA4 gene_id:1413|Hs108|chr22 (196 aa)
initn: 329 init1: 141 opt: 351 Z-score: 450.0 bits: 89.9 E(32554): 9.6e-19
Smith-Waterman score: 376; 35.7% identity (65.4% similar) in 182 aa overlap (3-170:13-194)
10 20 30 40
pF1KE2 MGKITFYEDRAFQGRSYETTTDCPN-LQPYFSRCNSIRVESGCWMLYERP
:.. ... .:::: .: :..::. :. : :..: :: :. .:.
CCDS13 MTLQCTKSAGPWKMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 NYQGQQYLLRRGEYPDYQQWMGLS--DSIRSCCLIPQTVSH----RLRLYEREDHKGLMM
..:::::.:.:::::... : : . . : . : . .. :: ..:.:. :
CCDS13 GFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKG
70 80 90 100 110 120
110 120 130 140 150
pF1KE2 ELSEDCPSIQDR-FHLSEIRSLHVLEGCWVLYELPNYRGRQYLLR----PQEYRRCQDWG
:::.: ::.: .. .:. :.:: : :: ..:.::: ::.:. .:.. ..::
CCDS13 ELSDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWG
130 140 150 160 170 180
160 170
pF1KE2 --AMDAKAGSLRRVVDLY
: .. :.::.
CCDS13 SHAPTFQVQSIRRIQQ
190
174 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:05:05 2016 done: Sun Nov 6 18:05:05 2016
Total Scan time: 1.840 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]