Result of FASTA (omim) for
pFN21AE2213
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2213, 373 aa
1>>>pF1KE2213 373 - 373 aa - 373 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8678+/-0.000412; mu= 18.3929+/- 0.025
mean_var=55.7783+/-11.713, 0's: 0 Z-trim(111.1): 50 B-trim: 767 in 1/50
Lambda= 0.171728
statistics sampled from 19503 (19551) to 19503 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.605), E-opt: 0.2 (0.229), width: 16
Scan time: 7.170
The best scores are: opt bits E(85289)
NP_001164509 (OMIM: 300015,402500) acetylserotonin ( 373) 2468 619.8 3.1e-177
NP_004034 (OMIM: 300015,402500) acetylserotonin O- ( 373) 2468 619.8 3.1e-177
NP_001164510 (OMIM: 300015,402500) acetylserotonin ( 298) 1238 315.0 1.4e-85
XP_016885573 (OMIM: 300162,400011) PREDICTED: N-ac ( 512) 510 134.8 4.4e-31
XP_016885408 (OMIM: 300162,400011) PREDICTED: N-ac ( 512) 510 134.8 4.4e-31
XP_011543940 (OMIM: 300162,400011) PREDICTED: N-ac ( 538) 510 134.8 4.6e-31
XP_011544487 (OMIM: 300162,400011) PREDICTED: N-ac ( 538) 510 134.8 4.6e-31
NP_001166944 (OMIM: 300162,400011) N-acetylseroton ( 563) 510 134.8 4.7e-31
NP_001166945 (OMIM: 300162,400011) N-acetylseroton ( 605) 510 134.8 5e-31
XP_005274840 (OMIM: 300162,400011) PREDICTED: N-ac ( 621) 510 134.8 5.1e-31
NP_004183 (OMIM: 300162,400011) N-acetylserotonin ( 621) 510 134.8 5.1e-31
XP_005274491 (OMIM: 300162,400011) PREDICTED: N-ac ( 621) 510 134.8 5.1e-31
XP_016867166 (OMIM: 604368) PREDICTED: transmembra ( 559) 131 40.9 0.0087
XP_016867165 (OMIM: 604368) PREDICTED: transmembra ( 600) 131 40.9 0.0092
>>NP_001164509 (OMIM: 300015,402500) acetylserotonin O-m (373 aa)
initn: 2468 init1: 2468 opt: 2468 Z-score: 3302.8 bits: 619.8 E(85289): 3.1e-177
Smith-Waterman score: 2468; 99.7% identity (99.7% similar) in 373 aa overlap (1-373:1-373)
10 20 30 40 50 60
pF1KE2 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 PLMCDLGGTRIKLETIILSKLSQGQKTKHRVFSLIGGAGALAKECMSLYPGCKITVFDIP
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLMCDLGGTWIKLETIILSKLSQGQKTKHRVFSLIGGAGALAKECMSLYPGCKITVFDIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 EVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 CKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFK
310 320 330 340 350 360
370
pF1KE2 KTGAIYDAILARK
:::::::::::::
NP_001 KTGAIYDAILARK
370
>>NP_004034 (OMIM: 300015,402500) acetylserotonin O-meth (373 aa)
initn: 2468 init1: 2468 opt: 2468 Z-score: 3302.8 bits: 619.8 E(85289): 3.1e-177
Smith-Waterman score: 2468; 99.7% identity (99.7% similar) in 373 aa overlap (1-373:1-373)
10 20 30 40 50 60
pF1KE2 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 PLMCDLGGTRIKLETIILSKLSQGQKTKHRVFSLIGGAGALAKECMSLYPGCKITVFDIP
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PLMCDLGGTWIKLETIILSKLSQGQKTKHRVFSLIGGAGALAKECMSLYPGCKITVFDIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 EVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 CKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFK
310 320 330 340 350 360
370
pF1KE2 KTGAIYDAILARK
:::::::::::::
NP_004 KTGAIYDAILARK
370
>>NP_001164510 (OMIM: 300015,402500) acetylserotonin O-m (298 aa)
initn: 1238 init1: 1238 opt: 1238 Z-score: 1657.4 bits: 315.0 E(85289): 1.4e-85
Smith-Waterman score: 1823; 79.9% identity (79.9% similar) in 373 aa overlap (1-373:1-298)
10 20 30 40 50 60
pF1KE2 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 PLMCDLGGTRIKLETIILSKLSQGQKTKHRVFSLIGGAGALAKECMSLYPGCKITVFDIP
::::::::
NP_001 PLMCDLGG----------------------------------------------------
250 260 270 280 290 300
pF1KE2 EVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHT
:::::::::::::::::::::::::::::::::::::
NP_001 -----------------------DFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHT
190 200 210 220
310 320 330 340 350 360
pF1KE2 CKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFK
230 240 250 260 270 280
370
pF1KE2 KTGAIYDAILARK
:::::::::::::
NP_001 KTGAIYDAILARK
290
>>XP_016885573 (OMIM: 300162,400011) PREDICTED: N-acetyl (512 aa)
initn: 808 init1: 425 opt: 510 Z-score: 679.1 bits: 134.8 E(85289): 4.4e-31
Smith-Waterman score: 794; 40.3% identity (63.8% similar) in 367 aa overlap (10-373:178-509)
10 20 30
pF1KE2 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAE
::: . .:::.:. :..::.: ::::: .
XP_016 DEKAEAGEAGQATAEAECHRTRETLPPFPTRLL-ELIEGFMLSKGLLTACKLKVFDLLKD
150 160 170 180 190 200
40 50 60 70 80 90
pF1KE2 APGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSP
.: .: .:. : ::: : : :::::... ::. .: : ::: .. ::.. .
XP_016 E-APQKAADIASKVDASACGMERLLDICAAMGLLEKTEQG----YSNTETANVYLASDGE
210 220 230 240 250 260
100 110 120 130 140 150
pF1KE2 TSQCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFGVPAEELFT-AIYRSEGERLQFMQ
: ... . . .. . .: :.::: ::. ...: ::.:: : :.: ::.::.
XP_016 YSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMR
270 280 290 300 310 320
160 170 180 190 200 210
pF1KE2 ALQEVWSVNGRSVLTAFDLSVFPLMCDLGGTRIKLETIILSKLSQGQKTKHRVFSLIGGA
:.. . .... .: :::.:: : ::.:: .
XP_016 AMHGMTKLTACQVATAFNLSRFSSACDVGGC----------------------------T
330 340 350
220 230 240 250 260 270
pF1KE2 GALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEE--QIDFQEGDFFKDPLPEADLY
::::.: :: ..::::.:... : ::. . :: : ::::.:::: :.::
XP_016 GALARELAREYPRMQVTVFDLPDIIELAA-HFQPPGPQAVQIHFAAGDFFRDPLPSAELY
360 370 380 390 400 410
280 290 300 310 320 330
pF1KE2 ILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTE
.: :.:::: : : .:: :. ..::::.:.:..:.::::..: . . :::::::::
XP_016 VLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTE
420 430 440 450 460 470
340 350 360 370
pF1KE2 GQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK
:.::. .:. :: ::.. : . :.. ::::: :
XP_016 GKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP
480 490 500 510
>>XP_016885408 (OMIM: 300162,400011) PREDICTED: N-acetyl (512 aa)
initn: 808 init1: 425 opt: 510 Z-score: 679.1 bits: 134.8 E(85289): 4.4e-31
Smith-Waterman score: 794; 40.3% identity (63.8% similar) in 367 aa overlap (10-373:178-509)
10 20 30
pF1KE2 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAE
::: . .:::.:. :..::.: ::::: .
XP_016 DEKAEAGEAGQATAEAECHRTRETLPPFPTRLL-ELIEGFMLSKGLLTACKLKVFDLLKD
150 160 170 180 190 200
40 50 60 70 80 90
pF1KE2 APGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSP
.: .: .:. : ::: : : :::::... ::. .: : ::: .. ::.. .
XP_016 E-APQKAADIASKVDASACGMERLLDICAAMGLLEKTEQG----YSNTETANVYLASDGE
210 220 230 240 250 260
100 110 120 130 140 150
pF1KE2 TSQCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFGVPAEELFT-AIYRSEGERLQFMQ
: ... . . .. . .: :.::: ::. ...: ::.:: : :.: ::.::.
XP_016 YSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMR
270 280 290 300 310 320
160 170 180 190 200 210
pF1KE2 ALQEVWSVNGRSVLTAFDLSVFPLMCDLGGTRIKLETIILSKLSQGQKTKHRVFSLIGGA
:.. . .... .: :::.:: : ::.:: .
XP_016 AMHGMTKLTACQVATAFNLSRFSSACDVGGC----------------------------T
330 340 350
220 230 240 250 260 270
pF1KE2 GALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEE--QIDFQEGDFFKDPLPEADLY
::::.: :: ..::::.:... : ::. . :: : ::::.:::: :.::
XP_016 GALARELAREYPRMQVTVFDLPDIIELAA-HFQPPGPQAVQIHFAAGDFFRDPLPSAELY
360 370 380 390 400 410
280 290 300 310 320 330
pF1KE2 ILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTE
.: :.:::: : : .:: :. ..::::.:.:..:.::::..: . . :::::::::
XP_016 VLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTE
420 430 440 450 460 470
340 350 360 370
pF1KE2 GQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK
:.::. .:. :: ::.. : . :.. ::::: :
XP_016 GKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP
480 490 500 510
>>XP_011543940 (OMIM: 300162,400011) PREDICTED: N-acetyl (538 aa)
initn: 808 init1: 425 opt: 510 Z-score: 678.7 bits: 134.8 E(85289): 4.6e-31
Smith-Waterman score: 794; 40.3% identity (63.8% similar) in 367 aa overlap (10-373:204-535)
10 20 30
pF1KE2 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAE
::: . .:::.:. :..::.: ::::: .
XP_011 DEKAEAGEAGQATAEAECHRTRETLPPFPTRLL-ELIEGFMLSKGLLTACKLKVFDLLKD
180 190 200 210 220 230
40 50 60 70 80 90
pF1KE2 APGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSP
.: .: .:. : ::: : : :::::... ::. .: : ::: .. ::.. .
XP_011 E-APQKAADIASKVDASACGMERLLDICAAMGLLEKTEQG----YSNTETANVYLASDGE
240 250 260 270 280
100 110 120 130 140 150
pF1KE2 TSQCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFGVPAEELFT-AIYRSEGERLQFMQ
: ... . . .. . .: :.::: ::. ...: ::.:: : :.: ::.::.
XP_011 YSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMR
290 300 310 320 330 340
160 170 180 190 200 210
pF1KE2 ALQEVWSVNGRSVLTAFDLSVFPLMCDLGGTRIKLETIILSKLSQGQKTKHRVFSLIGGA
:.. . .... .: :::.:: : ::.:: .
XP_011 AMHGMTKLTACQVATAFNLSRFSSACDVGGC----------------------------T
350 360 370
220 230 240 250 260 270
pF1KE2 GALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEE--QIDFQEGDFFKDPLPEADLY
::::.: :: ..::::.:... : ::. . :: : ::::.:::: :.::
XP_011 GALARELAREYPRMQVTVFDLPDIIELAA-HFQPPGPQAVQIHFAAGDFFRDPLPSAELY
380 390 400 410 420 430
280 290 300 310 320 330
pF1KE2 ILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTE
.: :.:::: : : .:: :. ..::::.:.:..:.::::..: . . :::::::::
XP_011 VLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTE
440 450 460 470 480 490
340 350 360 370
pF1KE2 GQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK
:.::. .:. :: ::.. : . :.. ::::: :
XP_011 GKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP
500 510 520 530
>>XP_011544487 (OMIM: 300162,400011) PREDICTED: N-acetyl (538 aa)
initn: 808 init1: 425 opt: 510 Z-score: 678.7 bits: 134.8 E(85289): 4.6e-31
Smith-Waterman score: 794; 40.3% identity (63.8% similar) in 367 aa overlap (10-373:204-535)
10 20 30
pF1KE2 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAE
::: . .:::.:. :..::.: ::::: .
XP_011 DEKAEAGEAGQATAEAECHRTRETLPPFPTRLL-ELIEGFMLSKGLLTACKLKVFDLLKD
180 190 200 210 220 230
40 50 60 70 80 90
pF1KE2 APGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSP
.: .: .:. : ::: : : :::::... ::. .: : ::: .. ::.. .
XP_011 E-APQKAADIASKVDASACGMERLLDICAAMGLLEKTEQG----YSNTETANVYLASDGE
240 250 260 270 280
100 110 120 130 140 150
pF1KE2 TSQCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFGVPAEELFT-AIYRSEGERLQFMQ
: ... . . .. . .: :.::: ::. ...: ::.:: : :.: ::.::.
XP_011 YSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMR
290 300 310 320 330 340
160 170 180 190 200 210
pF1KE2 ALQEVWSVNGRSVLTAFDLSVFPLMCDLGGTRIKLETIILSKLSQGQKTKHRVFSLIGGA
:.. . .... .: :::.:: : ::.:: .
XP_011 AMHGMTKLTACQVATAFNLSRFSSACDVGGC----------------------------T
350 360 370
220 230 240 250 260 270
pF1KE2 GALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEE--QIDFQEGDFFKDPLPEADLY
::::.: :: ..::::.:... : ::. . :: : ::::.:::: :.::
XP_011 GALARELAREYPRMQVTVFDLPDIIELAA-HFQPPGPQAVQIHFAAGDFFRDPLPSAELY
380 390 400 410 420 430
280 290 300 310 320 330
pF1KE2 ILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTE
.: :.:::: : : .:: :. ..::::.:.:..:.::::..: . . :::::::::
XP_011 VLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTE
440 450 460 470 480 490
340 350 360 370
pF1KE2 GQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK
:.::. .:. :: ::.. : . :.. ::::: :
XP_011 GKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP
500 510 520 530
>>NP_001166944 (OMIM: 300162,400011) N-acetylserotonin O (563 aa)
initn: 808 init1: 425 opt: 510 Z-score: 678.4 bits: 134.8 E(85289): 4.7e-31
Smith-Waterman score: 794; 40.3% identity (63.8% similar) in 367 aa overlap (10-373:229-560)
10 20 30
pF1KE2 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAE
::: . .:::.:. :..::.: ::::: .
NP_001 DEKAEAGEAGQATAEAECHRTRETLPPFPTRLL-ELIEGFMLSKGLLTACKLKVFDLLKD
200 210 220 230 240 250
40 50 60 70 80 90
pF1KE2 APGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSP
.: .: .:. : ::: : : :::::... ::. .: : ::: .. ::.. .
NP_001 E-APQKAADIASKVDASACGMERLLDICAAMGLLEKTEQG----YSNTETANVYLASDGE
260 270 280 290 300 310
100 110 120 130 140 150
pF1KE2 TSQCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFGVPAEELFT-AIYRSEGERLQFMQ
: ... . . .. . .: :.::: ::. ...: ::.:: : :.: ::.::.
NP_001 YSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMR
320 330 340 350 360 370
160 170 180 190 200 210
pF1KE2 ALQEVWSVNGRSVLTAFDLSVFPLMCDLGGTRIKLETIILSKLSQGQKTKHRVFSLIGGA
:.. . .... .: :::.:: : ::.:: .
NP_001 AMHGMTKLTACQVATAFNLSRFSSACDVGGC----------------------------T
380 390 400
220 230 240 250 260 270
pF1KE2 GALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEE--QIDFQEGDFFKDPLPEADLY
::::.: :: ..::::.:... : ::. . :: : ::::.:::: :.::
NP_001 GALARELAREYPRMQVTVFDLPDIIELAA-HFQPPGPQAVQIHFAAGDFFRDPLPSAELY
410 420 430 440 450 460
280 290 300 310 320 330
pF1KE2 ILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTE
.: :.:::: : : .:: :. ..::::.:.:..:.::::..: . . :::::::::
NP_001 VLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTE
470 480 490 500 510 520
340 350 360 370
pF1KE2 GQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK
:.::. .:. :: ::.. : . :.. ::::: :
NP_001 GKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP
530 540 550 560
>>NP_001166945 (OMIM: 300162,400011) N-acetylserotonin O (605 aa)
initn: 808 init1: 425 opt: 510 Z-score: 678.0 bits: 134.8 E(85289): 5e-31
Smith-Waterman score: 794; 40.3% identity (63.8% similar) in 367 aa overlap (10-373:271-602)
10 20 30
pF1KE2 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAE
::: . .:::.:. :..::.: ::::: .
NP_001 DEKAEAGEAGQATAEAECHRTRETLPPFPTRLL-ELIEGFMLSKGLLTACKLKVFDLLKD
250 260 270 280 290
40 50 60 70 80 90
pF1KE2 APGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSP
.: .: .:. : ::: : : :::::... ::. .: : ::: .. ::.. .
NP_001 E-APQKAADIASKVDASACGMERLLDICAAMGLLEKTEQG----YSNTETANVYLASDGE
300 310 320 330 340 350
100 110 120 130 140 150
pF1KE2 TSQCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFGVPAEELFT-AIYRSEGERLQFMQ
: ... . . .. . .: :.::: ::. ...: ::.:: : :.: ::.::.
NP_001 YSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMR
360 370 380 390 400 410
160 170 180 190 200 210
pF1KE2 ALQEVWSVNGRSVLTAFDLSVFPLMCDLGGTRIKLETIILSKLSQGQKTKHRVFSLIGGA
:.. . .... .: :::.:: : ::.:: .
NP_001 AMHGMTKLTACQVATAFNLSRFSSACDVGGC----------------------------T
420 430 440
220 230 240 250 260 270
pF1KE2 GALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEE--QIDFQEGDFFKDPLPEADLY
::::.: :: ..::::.:... : ::. . :: : ::::.:::: :.::
NP_001 GALARELAREYPRMQVTVFDLPDIIELAA-HFQPPGPQAVQIHFAAGDFFRDPLPSAELY
450 460 470 480 490 500
280 290 300 310 320 330
pF1KE2 ILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTE
.: :.:::: : : .:: :. ..::::.:.:..:.::::..: . . :::::::::
NP_001 VLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTE
510 520 530 540 550 560
340 350 360 370
pF1KE2 GQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK
:.::. .:. :: ::.. : . :.. ::::: :
NP_001 GKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP
570 580 590 600
>>XP_005274840 (OMIM: 300162,400011) PREDICTED: N-acetyl (621 aa)
initn: 808 init1: 425 opt: 510 Z-score: 677.8 bits: 134.8 E(85289): 5.1e-31
Smith-Waterman score: 794; 40.3% identity (63.8% similar) in 367 aa overlap (10-373:287-618)
10 20 30
pF1KE2 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAE
::: . .:::.:. :..::.: ::::: .
XP_005 DEKAEAGEAGQATAEAECHRTRETLPPFPTRLL-ELIEGFMLSKGLLTACKLKVFDLLKD
260 270 280 290 300 310
40 50 60 70 80 90
pF1KE2 APGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSP
.: .: .:. : ::: : : :::::... ::. .: : ::: .. ::.. .
XP_005 E-APQKAADIASKVDASACGMERLLDICAAMGLLEKTEQG----YSNTETANVYLASDGE
320 330 340 350 360 370
100 110 120 130 140 150
pF1KE2 TSQCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFGVPAEELFT-AIYRSEGERLQFMQ
: ... . . .. . .: :.::: ::. ...: ::.:: : :.: ::.::.
XP_005 YSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMR
380 390 400 410 420 430
160 170 180 190 200 210
pF1KE2 ALQEVWSVNGRSVLTAFDLSVFPLMCDLGGTRIKLETIILSKLSQGQKTKHRVFSLIGGA
:.. . .... .: :::.:: : ::.:: .
XP_005 AMHGMTKLTACQVATAFNLSRFSSACDVGGC----------------------------T
440 450 460
220 230 240 250 260 270
pF1KE2 GALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEE--QIDFQEGDFFKDPLPEADLY
::::.: :: ..::::.:... : ::. . :: : ::::.:::: :.::
XP_005 GALARELAREYPRMQVTVFDLPDIIELAA-HFQPPGPQAVQIHFAAGDFFRDPLPSAELY
470 480 490 500 510 520
280 290 300 310 320 330
pF1KE2 ILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTE
.: :.:::: : : .:: :. ..::::.:.:..:.::::..: . . :::::::::
XP_005 VLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTE
530 540 550 560 570 580
340 350 360 370
pF1KE2 GQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK
:.::. .:. :: ::.. : . :.. ::::: :
XP_005 GKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP
590 600 610 620
373 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:32:53 2016 done: Sun Nov 6 04:32:54 2016
Total Scan time: 7.170 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]