Result of FASTA (ccds) for
pFN21AE2185
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2185, 282 aa
1>>>pF1KE2185 282 - 282 aa - 282 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3036+/-0.0012; mu= 9.8702+/- 0.072
mean_var=102.1840+/-20.796, 0's: 0 Z-trim(102.3): 100 B-trim: 5 in 2/51
Lambda= 0.126877
statistics sampled from 6799 (6901) to 6799 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.569), E-opt: 0.2 (0.212), width: 16
Scan time: 2.250
The best scores are: opt bits E(32554)
CCDS894.1 VTCN1 gene_id:79679|Hs108|chr1 ( 282) 1808 342.0 2.9e-94
CCDS58019.1 VTCN1 gene_id:79679|Hs108|chr1 ( 187) 1206 231.7 3.1e-61
CCDS58020.1 VTCN1 gene_id:79679|Hs108|chr1 ( 166) 870 170.1 9.3e-43
CCDS10251.1 CD276 gene_id:80381|Hs108|chr15 ( 316) 335 72.4 4.7e-13
CCDS32288.1 CD276 gene_id:80381|Hs108|chr15 ( 534) 325 70.7 2.5e-12
CCDS47358.1 BTNL3 gene_id:10917|Hs108|chr5 ( 466) 308 67.6 2e-11
CCDS74975.1 HHLA2 gene_id:11148|Hs108|chr3 ( 397) 298 65.7 6.2e-11
CCDS46883.1 HHLA2 gene_id:11148|Hs108|chr3 ( 414) 298 65.7 6.4e-11
>>CCDS894.1 VTCN1 gene_id:79679|Hs108|chr1 (282 aa)
initn: 1808 init1: 1808 opt: 1808 Z-score: 1805.7 bits: 342.0 E(32554): 2.9e-94
Smith-Waterman score: 1808; 100.0% identity (100.0% similar) in 282 aa overlap (1-282:1-282)
10 20 30 40 50 60
pF1KE2 MASLGQILFWSIISIIIILAGAIALIIGFGISGRHSITVTTVASAGNIGEDGILSCTFEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 MASLGQILFWSIISIIIILAGAIALIIGFGISGRHSITVTTVASAGNIGEDGILSCTFEP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 DIKLSDIVIQWLKEGVLGLVHEFKEGKDELSEQDEMFRGRTAVFADQVIVGNASLRLKNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 DIKLSDIVIQWLKEGVLGLVHEFKEGKDELSEQDEMFRGRTAVFADQVIVGNASLRLKNV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 QLTDAGTYKCYIITSKGKGNANLEYKTGAFSMPEVNVDYNASSETLRCEAPRWFPQPTVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 QLTDAGTYKCYIITSKGKGNANLEYKTGAFSMPEVNVDYNASSETLRCEAPRWFPQPTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 WASQVDQGANFSEVSNTSFELNSENVTMKVVSVLYNVTINNTYSCMIENDIAKATGDIKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 WASQVDQGANFSEVSNTSFELNSENVTMKVVSVLYNVTINNTYSCMIENDIAKATGDIKV
190 200 210 220 230 240
250 260 270 280
pF1KE2 TESEIKRRSHLQLLNSKASLCVSSFFAISWALLPLSPYLMLK
::::::::::::::::::::::::::::::::::::::::::
CCDS89 TESEIKRRSHLQLLNSKASLCVSSFFAISWALLPLSPYLMLK
250 260 270 280
>>CCDS58019.1 VTCN1 gene_id:79679|Hs108|chr1 (187 aa)
initn: 1206 init1: 1206 opt: 1206 Z-score: 1212.8 bits: 231.7 E(32554): 3.1e-61
Smith-Waterman score: 1206; 100.0% identity (100.0% similar) in 187 aa overlap (96-282:1-187)
70 80 90 100 110 120
pF1KE2 DIVIQWLKEGVLGLVHEFKEGKDELSEQDEMFRGRTAVFADQVIVGNASLRLKNVQLTDA
::::::::::::::::::::::::::::::
CCDS58 MFRGRTAVFADQVIVGNASLRLKNVQLTDA
10 20 30
130 140 150 160 170 180
pF1KE2 GTYKCYIITSKGKGNANLEYKTGAFSMPEVNVDYNASSETLRCEAPRWFPQPTVVWASQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 GTYKCYIITSKGKGNANLEYKTGAFSMPEVNVDYNASSETLRCEAPRWFPQPTVVWASQV
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE2 DQGANFSEVSNTSFELNSENVTMKVVSVLYNVTINNTYSCMIENDIAKATGDIKVTESEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 DQGANFSEVSNTSFELNSENVTMKVVSVLYNVTINNTYSCMIENDIAKATGDIKVTESEI
100 110 120 130 140 150
250 260 270 280
pF1KE2 KRRSHLQLLNSKASLCVSSFFAISWALLPLSPYLMLK
:::::::::::::::::::::::::::::::::::::
CCDS58 KRRSHLQLLNSKASLCVSSFFAISWALLPLSPYLMLK
160 170 180
>>CCDS58020.1 VTCN1 gene_id:79679|Hs108|chr1 (166 aa)
initn: 870 init1: 870 opt: 870 Z-score: 881.1 bits: 170.1 E(32554): 9.3e-43
Smith-Waterman score: 870; 90.7% identity (92.7% similar) in 151 aa overlap (132-282:16-166)
110 120 130 140 150 160
pF1KE2 AVFADQVIVGNASLRLKNVQLTDAGTYKCYIITSKGKGNANLEYKTGAFSMPEVNVDYNA
:: : . . .:::::::::::::
CCDS58 MASLGQILFWSIISIIIILAGAIALIIGFGISAFSMPEVNVDYNA
10 20 30 40
170 180 190 200 210 220
pF1KE2 SSETLRCEAPRWFPQPTVVWASQVDQGANFSEVSNTSFELNSENVTMKVVSVLYNVTINN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SSETLRCEAPRWFPQPTVVWASQVDQGANFSEVSNTSFELNSENVTMKVVSVLYNVTINN
50 60 70 80 90 100
230 240 250 260 270 280
pF1KE2 TYSCMIENDIAKATGDIKVTESEIKRRSHLQLLNSKASLCVSSFFAISWALLPLSPYLML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 TYSCMIENDIAKATGDIKVTESEIKRRSHLQLLNSKASLCVSSFFAISWALLPLSPYLML
110 120 130 140 150 160
pF1KE2 K
:
CCDS58 K
>>CCDS10251.1 CD276 gene_id:80381|Hs108|chr15 (316 aa)
initn: 224 init1: 119 opt: 335 Z-score: 347.8 bits: 72.4 E(32554): 4.7e-13
Smith-Waterman score: 335; 29.8% identity (58.7% similar) in 235 aa overlap (18-241:12-238)
10 20 30 40 50
pF1KE2 MASLGQILFWSIISIIIILAGAIALIIGFGISGRHSITVTTVASAGNIGEDGILSCTF--
. .:: . : ..: . : .. .: :. : :.:
CCDS10 MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSP
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 EPDIKLSDIVIQWLKEGVLGLVHEFKEGKDELSEQDEMFRGRTAVFADQVIVGNASLRLK
:: ..:... . : . ::: : ::.: : . .:::.: : . :::::::.
CCDS10 EPGFSLAQLNLIWQLTDTKQLVHSFAEGQD----QGSAYANRTALFPDLLAQGNASLRLQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 NVQLTDAGTYKCYIITSKGKGNANLEYKTGA-FSMPEVNVDYN-----ASSETLRCEAPR
:...: :.. :.. . . :.: . ...: .: : .... : ... :. : . :
CCDS10 RVRVADEGSFTCFV-SIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYR
120 130 140 150 160
180 190 200 210 220 230
pF1KE2 WFPQPTVVWASQVDQGANFSEVSNTSFELNSENVTMKVVSVLYNVT-INNTYSCMIENDI
.:. : : : ::. .. .:: .. .:. . : ::: : :.::::...: .
CCDS10 GYPEAEVFW--QDGQGVPLTGNVTTS-QMANEQGLFDVHSVLRVVLGANGTYSCLVRNPV
170 180 190 200 210 220
240 250 260 270 280
pF1KE2 AK--ATGDIKVTESEIKRRSHLQLLNSKASLCVSSFFAISWALLPLSPYLMLK
. : :.. .:
CCDS10 LQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVALAFVCWRKIKQSCEEENAGAE
230 240 250 260 270 280
>>CCDS32288.1 CD276 gene_id:80381|Hs108|chr15 (534 aa)
initn: 329 init1: 119 opt: 325 Z-score: 334.7 bits: 70.7 E(32554): 2.5e-12
Smith-Waterman score: 325; 31.7% identity (61.0% similar) in 205 aa overlap (48-241:260-456)
20 30 40 50 60 70
pF1KE2 ILAGAIALIIGFGISGRHSITVTTVASAGNIGEDGILSCTF--EPDIKLSDIVIQWLKEG
.: :. : :.: :: ..:... . :
CCDS32 DAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTD
230 240 250 260 270 280
80 90 100 110 120 130
pF1KE2 VLGLVHEFKEGKDELSEQDEMFRGRTAVFADQVIVGNASLRLKNVQLTDAGTYKCYIITS
. ::: : ::.: : . .:::.: : . :::::::. :...: :.. :.. .
CCDS32 TKQLVHSFTEGRD----QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFV-SI
290 300 310 320 330 340
140 150 160 170 180
pF1KE2 KGKGNANLEYKTGA-FSMPEVNVDYN-----ASSETLRCEAPRWFPQPTVVWASQVDQGA
. :.: . ...: .: : .... : ... :. : . : .:. : : : ::.
CCDS32 RDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFW--QDGQGV
350 360 370 380 390 400
190 200 210 220 230 240
pF1KE2 NFSEVSNTSFELNSENVTMKVVSVLYNVT-INNTYSCMIENDIAK--ATGDIKVTESEIK
.. .:: .. .:. . : ::: : :.::::...: . . : :.. .:
CCDS32 PLTGNVTTS-QMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMT
410 420 430 440 450 460
250 260 270 280
pF1KE2 RRSHLQLLNSKASLCVSSFFAISWALLPLSPYLMLK
CCDS32 FPPEALWVTVGLSVCLIALLVALAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLK
470 480 490 500 510 520
>>CCDS47358.1 BTNL3 gene_id:10917|Hs108|chr5 (466 aa)
initn: 275 init1: 221 opt: 308 Z-score: 318.7 bits: 67.6 E(32554): 2e-11
Smith-Waterman score: 308; 29.8% identity (63.5% similar) in 178 aa overlap (19-192:1-176)
10 20 30 40 50
pF1KE2 MASLGQILFWSIISIIIILAGAIALIIGFG--ISGRHSITVTTVASAGNIGEDGILSCTF
.: .. :...: .::. ..: . .:::...::..
CCDS47 MAFVLILVLSFYELVSGQWQVTGPGKFVQALVGEDAVFSCSL
10 20 30 40
60 70 80 90 100 110
pF1KE2 EPDIKLSDIVIQWLKEGVLGLVHEFKEGKDELSEQDEMFRGRTAVFADQVIVGNASLRLK
:. . . ...... ..:: ...:.: :.: ..:::: :.. : .:::::
CCDS47 FPETSAEAMEVRFFRNQFHAVVHLYRDGEDWESKQMPQYRGRTEFVKDSIAGGRVSLRLK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 NVQLTDAGTYKCYIITSKGKGNANLEYKTGAF-SMPEVN-VDYNASSETLRCEAPRWFPQ
:. .: : : :.. .. .:. : ...:. :.: .. : : .. : : . ::::
CCDS47 NITPSDIGLYGCWFSSQIYDEEATWELRVAALGSLPLISIVGYVDGGIQLLCLSSGWFPQ
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 PTVVWASQVDQGANFSEVSNTSFELNSENVTMKVVSVLYNVTINNTYSCMIENDIAKATG
::. : . :: ..:
CCDS47 PTAKWKGP--QGQDLSSDSRANADGYSLYDVEISIIVQENAGSILCSIHLAEQSHEVESK
170 180 190 200 210 220
>>CCDS74975.1 HHLA2 gene_id:11148|Hs108|chr3 (397 aa)
initn: 227 init1: 159 opt: 298 Z-score: 309.8 bits: 65.7 E(32554): 6.2e-11
Smith-Waterman score: 298; 26.6% identity (58.5% similar) in 241 aa overlap (46-281:41-271)
20 30 40 50 60 70
pF1KE2 IIILAGAIALIIGFGISGRHSITVTTVASAGNIGEDGILSCTFEPDIKLSDIVIQWLKEG
: . :: :: .:: . :..::.: .
CCDS74 LILITSLSGSQGIFPLAFFIYVPMNEQIVIGRLDEDIILPSSFE---RGSEVVIHWKYQD
20 30 40 50 60
80 90 100 110 120 130
pF1KE2 VLGLVHEFKEGKDELSEQDEMFRGRTAVFADQVIVGNASLRLKNVQLTDAGTYKCYIITS
:: . .:.:.: :: . .::..: ... ::::: .. :.: : : : ::. :.
CCDS74 SYK-VHSYYKGSDHLESQDPRYANRTSLFYNEIQNGNASLFFRRVSLLDEGIYTCYVGTA
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE2 KGKGNANLEYKTGAFSMPEVNVDYNASSETLRCEAPRWFPQPTVVWASQVDQGANFSEVS
. .. :.:.: : .. . .. : : . .:.: ..: ..:. . .:
CCDS74 IQVITNKVVLKVGVFLTPVMKYEKRNTNSFLICSVLSVYPRPIITW--KMDN----TPIS
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE2 NTSFELNSENVTMKVVSVLYNVTINNTYSCMIENDIAKAT--GDIKVTESEIKRRS-HLQ
....: .. .... : : . :..: : :::.. : : : . .. : .: :..
CCDS74 ENNMEETGSLDSFSINSPLNITGSNSSYECTIENSLLKQTWTGRWTMKDGLHKMQSEHVS
190 200 210 220 230 240
260 270 280
pF1KE2 LLNSKAS--LCVSSFFAISWALLPLSPYLMLK
: . .. . .. : ..:. . . . .:
CCDS74 LSCQPVNDYFSPNQDFKVTWSRMKSGTFSVLAYYLSSSQNTIINESRFSWNKELINQSDF
250 260 270 280 290 300
CCDS74 SMNLMDLNLSDSGEYLCNISSDEYTLLTIHTVHVEPSQETASHNKGLWILVPSAILAAFL
310 320 330 340 350 360
>>CCDS46883.1 HHLA2 gene_id:11148|Hs108|chr3 (414 aa)
initn: 227 init1: 159 opt: 298 Z-score: 309.6 bits: 65.7 E(32554): 6.4e-11
Smith-Waterman score: 298; 26.6% identity (58.5% similar) in 241 aa overlap (46-281:41-271)
20 30 40 50 60 70
pF1KE2 IIILAGAIALIIGFGISGRHSITVTTVASAGNIGEDGILSCTFEPDIKLSDIVIQWLKEG
: . :: :: .:: . :..::.: .
CCDS46 LILITSLSGSQGIFPLAFFIYVPMNEQIVIGRLDEDIILPSSFE---RGSEVVIHWKYQD
20 30 40 50 60
80 90 100 110 120 130
pF1KE2 VLGLVHEFKEGKDELSEQDEMFRGRTAVFADQVIVGNASLRLKNVQLTDAGTYKCYIITS
:: . .:.:.: :: . .::..: ... ::::: .. :.: : : : ::. :.
CCDS46 SYK-VHSYYKGSDHLESQDPRYANRTSLFYNEIQNGNASLFFRRVSLLDEGIYTCYVGTA
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE2 KGKGNANLEYKTGAFSMPEVNVDYNASSETLRCEAPRWFPQPTVVWASQVDQGANFSEVS
. .. :.:.: : .. . .. : : . .:.: ..: ..:. . .:
CCDS46 IQVITNKVVLKVGVFLTPVMKYEKRNTNSFLICSVLSVYPRPIITW--KMDN----TPIS
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE2 NTSFELNSENVTMKVVSVLYNVTINNTYSCMIENDIAKAT--GDIKVTESEIKRRS-HLQ
....: .. .... : : . :..: : :::.. : : : . .. : .: :..
CCDS46 ENNMEETGSLDSFSINSPLNITGSNSSYECTIENSLLKQTWTGRWTMKDGLHKMQSEHVS
190 200 210 220 230 240
260 270 280
pF1KE2 LLNSKAS--LCVSSFFAISWALLPLSPYLMLK
: . .. . .. : ..:. . . . .:
CCDS46 LSCQPVNDYFSPNQDFKVTWSRMKSGTFSVLAYYLSSSQNTIINESRFSWNKELINQSDF
250 260 270 280 290 300
CCDS46 SMNLMDLNLSDSGEYLCNISSDEYTLLTIHTVHVEPSQETASHNKGLWILVPSAILAAFL
310 320 330 340 350 360
282 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:57:54 2016 done: Sun Nov 6 18:57:54 2016
Total Scan time: 2.250 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]