Result of FASTA (ccds) for
pFN21AE2149
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2149, 607 aa
1>>>pF1KE2149 607 - 607 aa - 607 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.3200+/-0.00107; mu= -10.4333+/- 0.064
mean_var=475.5337+/-95.271, 0's: 0 Z-trim(116.9): 59 B-trim: 0 in 0/53
Lambda= 0.058814
statistics sampled from 17538 (17586) to 17538 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.54), width: 16
Scan time: 4.570
The best scores are: opt bits E(32554)
CCDS12561.1 NUMBL gene_id:9253|Hs108|chr19 ( 609) 4203 371.0 2.5e-102
CCDS77298.1 NUMBL gene_id:9253|Hs108|chr19 ( 568) 3896 345.0 1.6e-94
CCDS55927.1 NUMB gene_id:8650|Hs108|chr14 ( 592) 1820 168.8 1.8e-41
CCDS9814.1 NUMB gene_id:8650|Hs108|chr14 ( 640) 1660 155.3 2.3e-37
CCDS32115.1 NUMB gene_id:8650|Hs108|chr14 ( 603) 1423 135.1 2.5e-31
CCDS32116.1 NUMB gene_id:8650|Hs108|chr14 ( 651) 1263 121.6 3.2e-27
>>CCDS12561.1 NUMBL gene_id:9253|Hs108|chr19 (609 aa)
initn: 3057 init1: 3057 opt: 4203 Z-score: 1950.7 bits: 371.0 E(32554): 2.5e-102
Smith-Waterman score: 4203; 99.7% identity (99.7% similar) in 609 aa overlap (1-607:1-609)
10 20 30 40 50 60
pF1KE2 MSRSAAASGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MSRSAAASGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 SRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 SADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 SADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 GERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 KKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 VRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 NALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 NALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEV
370 380 390 400 410 420
430 440 450 460 470
pF1KE2 SQVAKAQQQQQQQQQQQQQQQQQQ--AASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVF
:::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
CCDS12 SQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVF
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 LPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAF
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 PPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNPFSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 PPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNPFSGD
550 560 570 580 590 600
600
pF1KE2 LQKTFEIEL
:::::::::
CCDS12 LQKTFEIEL
>>CCDS77298.1 NUMBL gene_id:9253|Hs108|chr19 (568 aa)
initn: 2750 init1: 2750 opt: 3896 Z-score: 1810.4 bits: 345.0 E(32554): 1.6e-94
Smith-Waterman score: 3896; 99.6% identity (99.6% similar) in 568 aa overlap (42-607:1-568)
20 30 40 50 60 70
pF1KE2 RRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEASRPHQWQADED
::::::::::::::::::::::::::::::
CCDS77 MNKLRQSLRRRKPAYVPEASRPHQWQADED
10 20 30
80 90 100 110 120 130
pF1KE2 AVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 AVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDK
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE2 TKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 TKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCA
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE2 FAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPDKKKAEAAAAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 FAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPDKKKAEAAAAPT
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE2 VAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 VAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPA
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE2 LSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 LSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSF
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE2 ASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 ASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQ
340 350 360 370 380 390
440 450 460 470 480
pF1KE2 QQQQQQQQQQQQQ--AASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFV
::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
CCDS77 QQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFV
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE2 PAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGS
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE2 QARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNPFSGDLQKTFEIEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 QARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNPFSGDLQKTFEIEL
520 530 540 550 560
>>CCDS55927.1 NUMB gene_id:8650|Hs108|chr14 (592 aa)
initn: 1943 init1: 1174 opt: 1820 Z-score: 858.1 bits: 168.8 E(32554): 1.8e-41
Smith-Waterman score: 2068; 56.9% identity (72.4% similar) in 624 aa overlap (42-607:1-592)
20 30 40 50 60 70
pF1KE2 RRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEASRPHQWQADED
:::::::.::.: .::::::::::::.::.
CCDS55 MNKLRQSFRRKKDVYVPEASRPHQWQTDEE
10 20 30
80 90 100 110 120 130
pF1KE2 AVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDK
.:: : :::::.:::::::.::::::.::::::.::: :.:.::.:::::::::::::.:
CCDS55 GVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAVKAVLWVSADGLRVVDEK
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE2 TKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCA
::::.::::::::::::::::.:.:::::::::::::::::::.:.::.:::::::::::
CCDS55 TKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCA
100 110 120 130 140 150
200 210 220 230 240
pF1KE2 FAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREA-----PDKKKAEA
:::::::::.:::::::::.::::::.:.::::::.. . . :::: : ::::.
CCDS55 FAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAET
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 ---AAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQ
... .:::: . :. ::: :.. . : ..: ::::::::.:::.::
CCDS55 DKIVVGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNP-------HAIPRRHAPIEQLARQ
220 230 240 250 260
310 320 330 340 350 360
pF1KE2 GSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINAL
:::::::::::: ::::::::::.::::::.::.::: .:..:::.: :...::..:
CCDS55 GSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVE----GEAESISSL
270 280 290 300 310
370 380 390 400 410
pF1KE2 CTQISSSFASAGAP---APGPPPATT---------GTSAWGEPS-VPPAAAFQPGHKRTP
:.::...:.. : :: :.:. :: ::. : . . :: ::.:::
CCDS55 CSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQGTE-WGQSSGAASPGLFQAGHRRTP
320 330 340 350 360 370
420 430 440 450 460 470
pF1KE2 SEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDA
:::.:::::::. ..::: : ::.:: . :.::: : . :
CCDS55 SEADRWLEEVSKSVRAQQPQ---------------ASAAP---LQPVLQPPPPTAISQPA
380 390 400 410 420
480 490 500 510
pF1KE2 APAQVAVFL---P-P----PHMQPPFVPA--YP-GLGYP-PMPRVPVVGITPSQMVANAF
.: : .:: : : : .:: :::: :: . :.: : : ::::::::::::::.:
CCDS55 SPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVF
430 440 450 460 470 480
520 530 540 550
pF1KE2 CSAAQLQ---PQPATLLGKAGAFP--------------PPAIPSAPGSQA-----RPRPN
.:.. : :. . : . .:: ::: :: : :
CCDS55 GTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPA-QHLNGSAAFNGVDDGRLA
490 500 510 520 530
560 570 580 590 600
pF1KE2 GAPWPPEPAPAPAPELDPFEAQWAALEGKA---TVEKPSNPFSGDLQKTFEIEL
.: : .:. . .:::::::::::.:. : .:.::::.::::::::::
CCDS55 SADRHTE-VPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL
540 550 560 570 580 590
>>CCDS9814.1 NUMB gene_id:8650|Hs108|chr14 (640 aa)
initn: 1943 init1: 1174 opt: 1660 Z-score: 784.3 bits: 155.3 E(32554): 2.3e-37
Smith-Waterman score: 1850; 54.3% identity (69.4% similar) in 591 aa overlap (42-549:1-562)
20 30 40 50 60 70
pF1KE2 RRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEASRPHQWQADED
:::::::.::.: .::::::::::::.::.
CCDS98 MNKLRQSFRRKKDVYVPEASRPHQWQTDEE
10 20 30
80 90 100 110 120 130
pF1KE2 AVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDK
.:: : :::::.:::::::.::::::.::::::.::: :.:.::.:::::::::::::.:
CCDS98 GVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAVKAVLWVSADGLRVVDEK
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE2 TKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCA
::::.::::::::::::::::.:.:::::::::::::::::::.:.::.:::::::::::
CCDS98 TKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCA
100 110 120 130 140 150
200 210 220 230 240
pF1KE2 FAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREA-----PDKKKAEA
:::::::::.:::::::::.::::::.:.::::::.. . . :::: : ::::.
CCDS98 FAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAET
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 ---AAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQ
... .:::: . :. ::: :.. . : ..: ::::::::.:::.::
CCDS98 DKIVVGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNP-------HAIPRRHAPIEQLARQ
220 230 240 250 260
310 320 330 340 350 360
pF1KE2 GSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINAL
:::::::::::: ::::::::::.::::::.::.::: .:..:::.: :...::..:
CCDS98 GSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVE----GEAESISSL
270 280 290 300 310
370 380
pF1KE2 CTQISSSFAS-----AGAP--------APGPP----------------PATTGT------
:.::...:.. ..:: :: : :: :.
CCDS98 CSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTALAPVAMP
320 330 340 350 360 370
390 400 410 420
pF1KE2 ------------------------SAWGEPS-VPPAAAFQPGHKRTPSEAERWLEEVSQV
. ::. : . . :: ::.::::::.:::::::.
CCDS98 VRETNPWAHAPDAANKEIAATCSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKS
380 390 400 410 420 430
430 440 450 460 470 480
pF1KE2 AKAQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFL---P
..::: : ::.:: . :.::: : . :.: : .:: :
CCDS98 VRAQQPQ---------------ASAAP---LQPVLQPPPPTAISQPASPFQGNAFLTSQP
440 450 460 470 480
490 500 510 520
pF1KE2 -P----PHMQPPFVPA--YP-GLGYP-PMPRVPVVGITPSQMVANAFCSAAQLQ---PQP
: : .:: :::: :: . :.: : : ::::::::::::::.: .:.. : :.
CCDS98 VPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQ
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE2 ATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATV
. : . .:: :: :
CCDS98 SPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCP
550 560 570 580 590 600
>>CCDS32115.1 NUMB gene_id:8650|Hs108|chr14 (603 aa)
initn: 1930 init1: 777 opt: 1423 Z-score: 676.0 bits: 135.1 E(32554): 2.5e-31
Smith-Waterman score: 2036; 55.9% identity (71.2% similar) in 635 aa overlap (42-607:1-603)
20 30 40 50 60 70
pF1KE2 RRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEASRPHQWQADED
:::::::.::.: .::::::::::::.::.
CCDS32 MNKLRQSFRRKKDVYVPEASRPHQWQTDEE
10 20 30
80 90 100 110 120
pF1KE2 AVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKA-----------MGRKSVKSVLWV
.:: : :::::.:::::::.::::::.::::::.::: :.:.::.::::
CCDS32 GVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 SADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDS
:::::::::.:::::.::::::::::::::::.:.:::::::::::::::::::.:.::.
CCDS32 SADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDT
100 110 120 130 140 150
190 200 210 220 230
pF1KE2 GERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREA--
::::::::::::::::::::.:::::::::.::::::.:.::::::.. . . ::::
CCDS32 GERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIM
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE2 ---PDKKKAEA---AAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPR
: ::::. ... .:::: . :. ::: :.. . : ..: ::::
CCDS32 KQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNP-------HAIPR
220 230 240 250 260
300 310 320 330 340 350
pF1KE2 RHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPP
::::.:::.:::::::::::::: ::::::::::.::::::.::.::: .:..:::.:
CCDS32 RHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVE--
270 280 290 300 310 320
360 370 380 390
pF1KE2 GAGDSDSINALCTQISSSFASAGAP---APGPPPATT---------GTSAWGEPS-VPPA
:...::..::.::...:.. : :: :.:. :: ::. : .
CCDS32 --GEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQGTE-WGQSSGAASP
330 340 350 360 370
400 410 420 430 440 450
pF1KE2 AAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQ
. :: ::.::::::.:::::::. ..::: : ::.:: . :.::
CCDS32 GLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ---------------ASAAP---LQPVLQ
380 390 400 410 420
460 470 480 490 500
pF1KE2 PFPAPVGPFDAAPAQVAVFL---P-P----PHMQPPFVPA--YP-GLGYP-PMPRVPVVG
: : . :.: : .:: : : : .:: :::: :: . :.: : : :::::
CCDS32 PPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVG
430 440 450 460 470 480
510 520 530 540 550
pF1KE2 ITPSQMVANAFCSAAQLQ---PQPATLLGKAGAFP--------------PPAIPSAPGSQ
:::::::::.: .:.. : :. . : . .:: ::: ::
CCDS32 ITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPA-QHLNGSA
490 500 510 520 530
560 570 580 590 600
pF1KE2 A-----RPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKA---TVEKPSNPFSGDLQKT
: : .: : .:. . .:::::::::::.:. : .:.::::.:::::
CCDS32 AFNGVDDGRLASADRHTE-VPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKT
540 550 560 570 580 590
pF1KE2 FEIEL
:::::
CCDS32 FEIEL
600
>>CCDS32116.1 NUMB gene_id:8650|Hs108|chr14 (651 aa)
initn: 1930 init1: 777 opt: 1263 Z-score: 602.2 bits: 121.6 E(32554): 3.2e-27
Smith-Waterman score: 1818; 53.3% identity (68.1% similar) in 602 aa overlap (42-549:1-573)
20 30 40 50 60 70
pF1KE2 RRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEASRPHQWQADED
:::::::.::.: .::::::::::::.::.
CCDS32 MNKLRQSFRRKKDVYVPEASRPHQWQTDEE
10 20 30
80 90 100 110 120
pF1KE2 AVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKA-----------MGRKSVKSVLWV
.:: : :::::.:::::::.::::::.::::::.::: :.:.::.::::
CCDS32 GVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 SADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDS
:::::::::.:::::.::::::::::::::::.:.:::::::::::::::::::.:.::.
CCDS32 SADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDT
100 110 120 130 140 150
190 200 210 220 230
pF1KE2 GERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREA--
::::::::::::::::::::.:::::::::.::::::.:.::::::.. . . ::::
CCDS32 GERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIM
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE2 ---PDKKKAEA---AAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPR
: ::::. ... .:::: . :. ::: :.. . : ..: ::::
CCDS32 KQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNP-------HAIPR
220 230 240 250 260
300 310 320 330 340 350
pF1KE2 RHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPP
::::.:::.:::::::::::::: ::::::::::.::::::.::.::: .:..:::.:
CCDS32 RHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVE--
270 280 290 300 310 320
360 370 380
pF1KE2 GAGDSDSINALCTQISSSFAS-----AGAP--------APGPP----------------P
:...::..::.::...:.. ..:: :: : :
CCDS32 --GEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQANGTDSAFHVLAKP
330 340 350 360 370
390 400 410
pF1KE2 ATTGT------------------------------SAWGEPS-VPPAAAFQPGHKRTPSE
: :. . ::. : . . :: ::.:::::
CCDS32 AHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQSSGAASPGLFQAGHRRTPSE
380 390 400 410 420 430
420 430 440 450 460 470
pF1KE2 AERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAP
:.:::::::. ..::: : ::.:: . :.::: : . :.:
CCDS32 ADRWLEEVSKSVRAQQPQ---------------ASAAP---LQPVLQPPPPTAISQPASP
440 450 460 470 480
480 490 500 510 520
pF1KE2 AQVAVFL---P-P----PHMQPPFVPA--YP-GLGYP-PMPRVPVVGITPSQMVANAFCS
: .:: : : : .:: :::: :: . :.: : : ::::::::::::::.: .
CCDS32 FQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGT
490 500 510 520 530 540
530 540 550 560 570
pF1KE2 AAQLQ---PQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEA
:.. : :. . : . .:: :: :
CCDS32 AGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASAD
550 560 570 580 590 600
580 590 600
pF1KE2 QWAALEGKATVEKPSNPFSGDLQKTFEIEL
CCDS32 RHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL
610 620 630 640 650
607 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:01:15 2016 done: Sun Nov 6 05:01:16 2016
Total Scan time: 4.570 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]