Result of FASTA (omim) for
pFN21AE2111
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2111, 826 aa
1>>>pF1KE2111 826 - 826 aa - 826 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4008+/-0.000312; mu= 13.2461+/- 0.020
mean_var=163.3277+/-33.531, 0's: 0 Z-trim(121.4): 110 B-trim: 410 in 1/55
Lambda= 0.100356
statistics sampled from 37748 (37888) to 37748 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.444), width: 16
Scan time: 11.500
The best scores are: opt bits E(85289)
NP_851393 (OMIM: 114550,603816,607864) axin-1 isof ( 826) 5656 831.2 0
XP_016879233 (OMIM: 114550,603816,607864) PREDICTE ( 875) 5656 831.2 0
XP_011520985 (OMIM: 114550,603816,607864) PREDICTE ( 880) 5636 828.3 0
NP_003493 (OMIM: 114550,603816,607864) axin-1 isof ( 862) 5011 737.8 4.8e-212
XP_016879232 (OMIM: 114550,603816,607864) PREDICTE ( 911) 5011 737.8 5e-212
XP_011520986 (OMIM: 114550,603816,607864) PREDICTE ( 867) 4991 734.9 3.6e-211
XP_011520984 (OMIM: 114550,603816,607864) PREDICTE ( 916) 4991 734.9 3.8e-211
XP_011520988 (OMIM: 114550,603816,607864) PREDICTE ( 581) 3001 446.6 1.5e-124
XP_016879236 (OMIM: 114550,603816,607864) PREDICTE ( 479) 2804 418.0 4.9e-116
XP_016879237 (OMIM: 114550,603816,607864) PREDICTE ( 478) 2800 417.5 7.2e-116
XP_016879235 (OMIM: 114550,603816,607864) PREDICTE ( 512) 2579 385.5 3.3e-106
XP_016879234 (OMIM: 114550,603816,607864) PREDICTE ( 582) 2503 374.5 7.4e-103
XP_016880682 (OMIM: 604025,608615) PREDICTED: axin ( 778) 418 72.8 6.8e-12
XP_016880683 (OMIM: 604025,608615) PREDICTED: axin ( 778) 418 72.8 6.8e-12
XP_011523623 (OMIM: 604025,608615) PREDICTED: axin ( 843) 417 72.7 8e-12
NP_004646 (OMIM: 604025,608615) axin-2 [Homo sapie ( 843) 417 72.7 8e-12
XP_011523622 (OMIM: 604025,608615) PREDICTED: axin ( 843) 417 72.7 8e-12
XP_016880681 (OMIM: 604025,608615) PREDICTED: axin ( 843) 417 72.7 8e-12
XP_011523621 (OMIM: 604025,608615) PREDICTED: axin ( 843) 417 72.7 8e-12
NP_001005339 (OMIM: 602856) regulator of G-protein ( 181) 270 50.8 6.5e-06
NP_002916 (OMIM: 602856) regulator of G-protein si ( 167) 266 50.2 9.2e-06
NP_001263191 (OMIM: 602189) regulator of G-protein ( 168) 263 49.8 1.2e-05
NP_602299 (OMIM: 602189) regulator of G-protein si ( 168) 263 49.8 1.2e-05
NP_001263190 (OMIM: 602189) regulator of G-protein ( 591) 270 51.2 1.6e-05
NP_652760 (OMIM: 602189) regulator of G-protein si ( 311) 263 50.0 2e-05
XP_011517199 (OMIM: 602189) PREDICTED: regulator o ( 519) 263 50.2 2.9e-05
XP_011517198 (OMIM: 602189) PREDICTED: regulator o ( 519) 263 50.2 2.9e-05
XP_006717293 (OMIM: 602189) PREDICTED: regulator o ( 519) 263 50.2 2.9e-05
XP_011517203 (OMIM: 602189) PREDICTED: regulator o ( 519) 263 50.2 2.9e-05
XP_016870495 (OMIM: 602189) PREDICTED: regulator o ( 519) 263 50.2 2.9e-05
XP_016870494 (OMIM: 602189) PREDICTED: regulator o ( 519) 263 50.2 2.9e-05
XP_011517202 (OMIM: 602189) PREDICTED: regulator o ( 519) 263 50.2 2.9e-05
XP_006717289 (OMIM: 602189) PREDICTED: regulator o ( 519) 263 50.2 2.9e-05
NP_001263189 (OMIM: 602189) regulator of G-protein ( 519) 263 50.2 2.9e-05
XP_011517200 (OMIM: 602189) PREDICTED: regulator o ( 519) 263 50.2 2.9e-05
NP_001269851 (OMIM: 602189) regulator of G-protein ( 519) 263 50.2 2.9e-05
XP_006717288 (OMIM: 602189) PREDICTED: regulator o ( 521) 263 50.2 2.9e-05
NP_001309144 (OMIM: 602189) regulator of G-protein ( 537) 263 50.2 3e-05
XP_011517196 (OMIM: 602189) PREDICTED: regulator o ( 545) 263 50.2 3e-05
XP_006717285 (OMIM: 602189) PREDICTED: regulator o ( 824) 263 50.3 4.1e-05
NP_570613 (OMIM: 602189) regulator of G-protein si ( 917) 263 50.4 4.4e-05
XP_016870493 (OMIM: 602189) PREDICTED: regulator o ( 961) 263 50.4 4.5e-05
XP_006717283 (OMIM: 602189) PREDICTED: regulator o (1086) 263 50.4 5e-05
NP_001269852 (OMIM: 602189) regulator of G-protein (1088) 263 50.4 5e-05
XP_006717282 (OMIM: 602189) PREDICTED: regulator o (1094) 263 50.5 5e-05
XP_016870492 (OMIM: 602189) PREDICTED: regulator o (1157) 263 50.5 5.2e-05
NP_652759 (OMIM: 602189) regulator of G-protein si (1198) 263 50.5 5.4e-05
NP_570138 (OMIM: 607192) regulator of G-protein si ( 235) 249 47.9 6.5e-05
NP_001241678 (OMIM: 145500,603276) regulator of G- ( 185) 247 47.5 6.7e-05
NP_001034241 (OMIM: 612407) regulator of G-protein ( 152) 239 46.2 0.00013
>>NP_851393 (OMIM: 114550,603816,607864) axin-1 isoform (826 aa)
initn: 5656 init1: 5656 opt: 5656 Z-score: 4432.7 bits: 831.2 E(85289): 0
Smith-Waterman score: 5656; 99.9% identity (100.0% similar) in 826 aa overlap (1-826:1-826)
10 20 30 40 50 60
pF1KE2 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EGEDSDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 ASRAPSKQRTRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 ASRAPSKQRTRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTK
730 740 750 760 770 780
790 800 810 820
pF1KE2 KGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD
::::::::::::::::::::::::::::::::::::::::::::::
NP_851 KGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD
790 800 810 820
>>XP_016879233 (OMIM: 114550,603816,607864) PREDICTED: a (875 aa)
initn: 5656 init1: 5656 opt: 5656 Z-score: 4432.4 bits: 831.2 E(85289): 0
Smith-Waterman score: 5656; 99.9% identity (100.0% similar) in 826 aa overlap (1-826:50-875)
10 20 30
pF1KE2 MNIQEQGFPLDLGASFTEDAPRPPVPGEEG
::::::::::::::::::::::::::::::
XP_016 RARDRLIHFGAVSTDVLGCSAHCSLTQSPKMNIQEQGFPLDLGASFTEDAPRPPVPGEEG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE2 ELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLH
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE2 SLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYIL
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE2 DNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEY
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE2 TRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQK
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE2 LLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDA
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE2 DTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPRTYRVPKEVRVEPQKFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPRTYRVPKEVRVEPQKFAE
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE2 ELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDSDPSSGPPGPCHKLPPAPAWHHFPPR
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_016 ELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGDPSSGPPGPCHKLPPAPAWHHFPPR
440 450 460 470 480 490
460 470 480 490 500 510
pF1KE2 CVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSGHVAKMPVALGGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSGHVAKMPVALGGAA
500 510 520 530 540 550
520 530 540 550 560 570
pF1KE2 SGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRRAQSSFAWGLEPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRRAQSSFAWGLEPHS
560 570 580 590 600 610
580 590 600 610 620 630
pF1KE2 HGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGASEDAEKNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGASEDAEKNQ
620 630 640 650 660 670
640 650 660 670 680 690
pF1KE2 KIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSRPLSLEHPWAGPQLRTSVQPSHLFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSRPLSLEHPWAGPQLRTSVQPSHLFI
680 690 700 710 720 730
700 710 720 730 740 750
pF1KE2 QDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQRTRSQRKVGGGSAQPCDSIVVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQRTRSQRKVGGGSAQPCDSIVVA
740 750 760 770 780 790
760 770 780 790 800 810
pF1KE2 YYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAV
800 810 820 830 840 850
820
pF1KE2 LPVFEEKIIGKVEKVD
::::::::::::::::
XP_016 LPVFEEKIIGKVEKVD
860 870
>>XP_011520985 (OMIM: 114550,603816,607864) PREDICTED: a (880 aa)
initn: 5642 init1: 3125 opt: 5636 Z-score: 4416.7 bits: 828.3 E(85289): 0
Smith-Waterman score: 5636; 99.3% identity (99.4% similar) in 831 aa overlap (1-826:50-880)
10 20 30
pF1KE2 MNIQEQGFPLDLGASFTEDAPRPPVPGEEG
::::::::::::::::::::::::::::::
XP_011 RARDRLIHFGAVSTDVLGCSAHCSLTQSPKMNIQEQGFPLDLGASFTEDAPRPPVPGEEG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE2 ELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLH
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE2 SLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYIL
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE2 DNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEY
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE2 TRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQK
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE2 LLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDA
320 330 340 350 360 370
340 350 360 370 380
pF1KE2 DTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIP-----RTYRVPKEVRVEP
:::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_011 DTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPSCPSQRTYRVPKEVRVEP
380 390 400 410 420 430
390 400 410 420 430 440
pF1KE2 QKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDSDPSSGPPGPCHKLPPAPAWH
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_011 QKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGDPSSGPPGPCHKLPPAPAWH
440 450 460 470 480 490
450 460 470 480 490 500
pF1KE2 HFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSGHVAKMPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSGHVAKMPVA
500 510 520 530 540 550
510 520 530 540 550 560
pF1KE2 LGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRRAQSSFAWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRRAQSSFAWG
560 570 580 590 600 610
570 580 590 600 610 620
pF1KE2 LEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGASED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGASED
620 630 640 650 660 670
630 640 650 660 670 680
pF1KE2 AEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSRPLSLEHPWAGPQLRTSVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSRPLSLEHPWAGPQLRTSVQP
680 690 700 710 720 730
690 700 710 720 730 740
pF1KE2 SHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQRTRSQRKVGGGSAQPCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQRTRSQRKVGGGSAQPCD
740 750 760 770 780 790
750 760 770 780 790 800
pF1KE2 SIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVR
800 810 820 830 840 850
810 820
pF1KE2 EDEAVLPVFEEKIIGKVEKVD
:::::::::::::::::::::
XP_011 EDEAVLPVFEEKIIGKVEKVD
860 870 880
>>NP_003493 (OMIM: 114550,603816,607864) axin-1 isoform (862 aa)
initn: 5010 init1: 5010 opt: 5011 Z-score: 3927.8 bits: 737.8 E(85289): 4.8e-212
Smith-Waterman score: 5549; 95.7% identity (95.8% similar) in 858 aa overlap (1-822:1-858)
10 20 30 40 50 60
pF1KE2 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EGEDSDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR
670 680 690 700 710 720
730 740
pF1KE2 ASRAPSKQR------------------------------------TRSQRKVGGGSAQPC
::::::::: :::::::::::::::
NP_003 ASRAPSKQRYVQEVMRRGRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPC
730 740 750 760 770 780
750 760 770 780 790 800
pF1KE2 DSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEV
790 800 810 820 830 840
810 820
pF1KE2 REDEAVLPVFEEKIIGKVEKVD
::::::::::::::::::
NP_003 REDEAVLPVFEEKIIGKVEKVD
850 860
>>XP_016879232 (OMIM: 114550,603816,607864) PREDICTED: a (911 aa)
initn: 5010 init1: 5010 opt: 5011 Z-score: 3927.5 bits: 737.8 E(85289): 5e-212
Smith-Waterman score: 5549; 95.7% identity (95.8% similar) in 858 aa overlap (1-822:50-907)
10 20 30
pF1KE2 MNIQEQGFPLDLGASFTEDAPRPPVPGEEG
::::::::::::::::::::::::::::::
XP_016 RARDRLIHFGAVSTDVLGCSAHCSLTQSPKMNIQEQGFPLDLGASFTEDAPRPPVPGEEG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE2 ELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLH
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE2 SLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYIL
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE2 DNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEY
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE2 TRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQK
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE2 LLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDA
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE2 DTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPRTYRVPKEVRVEPQKFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPRTYRVPKEVRVEPQKFAE
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE2 ELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDSDPSSGPPGPCHKLPPAPAWHHFPPR
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_016 ELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGDPSSGPPGPCHKLPPAPAWHHFPPR
440 450 460 470 480 490
460 470 480 490 500 510
pF1KE2 CVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSGHVAKMPVALGGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSGHVAKMPVALGGAA
500 510 520 530 540 550
520 530 540 550 560 570
pF1KE2 SGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRRAQSSFAWGLEPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRRAQSSFAWGLEPHS
560 570 580 590 600 610
580 590 600 610 620 630
pF1KE2 HGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGASEDAEKNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGASEDAEKNQ
620 630 640 650 660 670
640 650 660 670 680 690
pF1KE2 KIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSRPLSLEHPWAGPQLRTSVQPSHLFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSRPLSLEHPWAGPQLRTSVQPSHLFI
680 690 700 710 720 730
700 710 720
pF1KE2 QDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQR---------------------
:::::::::::::::::::::::::::::::::::::::
XP_016 QDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQRYVQEVMRRGRACVRPACAPVL
740 750 760 770 780 790
730 740 750 760 770
pF1KE2 ---------------TRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQF
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVVPAVSDMELSETETRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQF
800 810 820 830 840 850
780 790 800 810 820
pF1KE2 KELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD
860 870 880 890 900 910
>>XP_011520986 (OMIM: 114550,603816,607864) PREDICTED: a (867 aa)
initn: 4996 init1: 2531 opt: 4991 Z-score: 3912.1 bits: 734.9 E(85289): 3.6e-211
Smith-Waterman score: 5500; 95.1% identity (95.2% similar) in 858 aa overlap (1-817:1-858)
10 20 30 40 50 60
pF1KE2 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 QVNGRVPLPHIP-----RTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKR
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_011 QVNGRVPLPHIPSCPSQRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 VRMEEEGEDSDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHV
:::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRMEEEGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 QRVLRTPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRVLRTPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 HHHVHHSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHHVHHSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHS
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 GKVGVACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKVGVACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSG
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 TRKPQPHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRKPQPHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLE
670 680 690 700 710 720
720 730
pF1KE2 EEEKRASRAPSKQR------------------------------------TRSQRKVGGG
:::::::::::::: ::::::::::
XP_011 EEEKRASRAPSKQRYVQEVMRRGRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGG
730 740 750 760 770 780
740 750 760 770 780 790
pF1KE2 SAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGV
790 800 810 820 830 840
800 810 820
pF1KE2 VFEEVREDEAVLPVFEEKIIGKVEKVD
::::::::::::::::::
XP_011 VFEEVREDEAVLPVFEEKIIGKVEKVD
850 860
>>XP_011520984 (OMIM: 114550,603816,607864) PREDICTED: a (916 aa)
initn: 4996 init1: 2531 opt: 4991 Z-score: 3911.8 bits: 734.9 E(85289): 3.8e-211
Smith-Waterman score: 5500; 95.1% identity (95.2% similar) in 858 aa overlap (1-817:50-907)
10 20 30
pF1KE2 MNIQEQGFPLDLGASFTEDAPRPPVPGEEG
::::::::::::::::::::::::::::::
XP_011 RARDRLIHFGAVSTDVLGCSAHCSLTQSPKMNIQEQGFPLDLGASFTEDAPRPPVPGEEG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE2 ELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLH
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE2 SLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYIL
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE2 DNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEY
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE2 TRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQK
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE2 LLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDA
320 330 340 350 360 370
340 350 360 370 380
pF1KE2 DTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIP-----RTYRVPKEVRVEP
:::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_011 DTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPSCPSQRTYRVPKEVRVEP
380 390 400 410 420 430
390 400 410 420 430 440
pF1KE2 QKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDSDPSSGPPGPCHKLPPAPAWH
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_011 QKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGDPSSGPPGPCHKLPPAPAWH
440 450 460 470 480 490
450 460 470 480 490 500
pF1KE2 HFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSGHVAKMPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSGHVAKMPVA
500 510 520 530 540 550
510 520 530 540 550 560
pF1KE2 LGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRRAQSSFAWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRRAQSSFAWG
560 570 580 590 600 610
570 580 590 600 610 620
pF1KE2 LEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGASED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGASED
620 630 640 650 660 670
630 640 650 660 670 680
pF1KE2 AEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSRPLSLEHPWAGPQLRTSVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSRPLSLEHPWAGPQLRTSVQP
680 690 700 710 720 730
690 700 710 720
pF1KE2 SHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQR----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQRYVQEVMRRGRACVRPA
740 750 760 770 780 790
730 740 750 760
pF1KE2 --------------------TRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAV
::::::::::::::::::::::::::::::::::::::::
XP_011 CAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAV
800 810 820 830 840 850
770 780 790 800 810 820
pF1KE2 TLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD
860 870 880 890 900 910
>>XP_011520988 (OMIM: 114550,603816,607864) PREDICTED: a (581 aa)
initn: 3006 init1: 2479 opt: 3001 Z-score: 2357.3 bits: 446.6 E(85289): 1.5e-124
Smith-Waterman score: 3539; 92.6% identity (92.8% similar) in 571 aa overlap (293-822:7-577)
270 280 290 300 310 320
pF1KE2 PPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSE
::::::::::::::::::::::::::::::
XP_011 MLLERRRYGSWREPVNPYYVNAGYALAPATSANDSE
10 20 30
330 340 350 360 370
pF1KE2 QQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIP-----RTYRV
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_011 QQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPSCPSQRTYRV
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE2 PKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDSDPSSGPPGPCHK
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_011 PKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGDPSSGPPGPCHK
100 110 120 130 140 150
440 450 460 470 480 490
pF1KE2 LPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSG
160 170 180 190 200 210
500 510 520 530 540 550
pF1KE2 HVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRR
220 230 240 250 260 270
560 570 580 590 600 610
pF1KE2 AQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSAST
280 290 300 310 320 330
620 630 640 650 660 670
pF1KE2 EVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSRPLSLEHPWAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSRPLSLEHPWAGP
340 350 360 370 380 390
680 690 700 710 720
pF1KE2 QLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQR--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQRYVQEVMRR
400 410 420 430 440 450
730 740 750 760
pF1KE2 ----------------------------TRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYR
::::::::::::::::::::::::::::::::
XP_011 GRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYR
460 470 480 490 500 510
770 780 790 800 810 820
pF1KE2 TLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGK
520 530 540 550 560 570
pF1KE2 VEKVD
:
XP_011 VEKVD
580
>>XP_016879236 (OMIM: 114550,603816,607864) PREDICTED: a (479 aa)
initn: 2806 init1: 2531 opt: 2804 Z-score: 2204.3 bits: 418.0 E(85289): 4.9e-116
Smith-Waterman score: 2804; 97.7% identity (97.9% similar) in 429 aa overlap (1-424:50-478)
10 20 30
pF1KE2 MNIQEQGFPLDLGASFTEDAPRPPVPGEEG
::::::::::::::::::::::::::::::
XP_016 RARDRLIHFGAVSTDVLGCSAHCSLTQSPKMNIQEQGFPLDLGASFTEDAPRPPVPGEEG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE2 ELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLH
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE2 SLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYIL
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE2 DNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEY
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE2 TRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQK
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE2 LLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDA
320 330 340 350 360 370
340 350 360 370 380
pF1KE2 DTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIP-----RTYRVPKEVRVEP
:::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_016 DTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPSCPSQRTYRVPKEVRVEP
380 390 400 410 420 430
390 400 410 420 430 440
pF1KE2 QKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDSDPSSGPPGPCHKLPPAPAWH
::::::::::::::::::::::::::::::::: : .
XP_016 QKFAEELIHRLEAVQRTREAEEKLEERLKRVRMCAAGAER
440 450 460 470
450 460 470 480 490 500
pF1KE2 HFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSGHVAKMPVA
>>XP_016879237 (OMIM: 114550,603816,607864) PREDICTED: a (478 aa)
initn: 2806 init1: 2531 opt: 2800 Z-score: 2201.2 bits: 417.5 E(85289): 7.2e-116
Smith-Waterman score: 2800; 98.8% identity (98.8% similar) in 423 aa overlap (1-418:50-472)
10 20 30
pF1KE2 MNIQEQGFPLDLGASFTEDAPRPPVPGEEG
::::::::::::::::::::::::::::::
XP_016 RARDRLIHFGAVSTDVLGCSAHCSLTQSPKMNIQEQGFPLDLGASFTEDAPRPPVPGEEG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE2 ELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLH
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE2 SLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYIL
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE2 DNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEY
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE2 TRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQK
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE2 LLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDA
320 330 340 350 360 370
340 350 360 370 380
pF1KE2 DTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIP-----RTYRVPKEVRVEP
:::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_016 DTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPSCPSQRTYRVPKEVRVEP
380 390 400 410 420 430
390 400 410 420 430 440
pF1KE2 QKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDSDPSSGPPGPCHKLPPAPAWH
:::::::::::::::::::::::::::::::::
XP_016 QKFAEELIHRLEAVQRTREAEEKLEERLKRVRMISFSTC
440 450 460 470
450 460 470 480 490 500
pF1KE2 HFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSGHVAKMPVA
826 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:46:51 2016 done: Sun Nov 6 05:46:53 2016
Total Scan time: 11.500 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]