Result of FASTA (omim) for
pFN21AE2079
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2079, 752 aa
1>>>pF1KE2079 752 - 752 aa - 752 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7427+/-0.000446; mu= 18.7150+/- 0.028
mean_var=117.5188+/-23.008, 0's: 0 Z-trim(113.4): 329 B-trim: 0 in 0/53
Lambda= 0.118310
statistics sampled from 22354 (22765) to 22354 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.267), width: 16
Scan time: 8.790
The best scores are: opt bits E(85289)
NP_000054 (OMIM: 217000,613927,615489) complement ( 752) 5174 895.3 0
NP_001269387 (OMIM: 217000,613927,615489) compleme ( 723) 4561 790.6 0
NP_001139375 (OMIM: 217000,613927,615489) compleme ( 620) 4104 712.6 1.2e-204
NP_001269386 (OMIM: 217000,613927,615489) compleme ( 506) 3171 553.2 9.4e-157
NP_001171534 (OMIM: 217000,613927,615489) compleme ( 538) 2902 507.3 6.5e-143
NP_001269388 (OMIM: 217000,613927,615489) compleme ( 328) 2007 354.3 4.5e-97
NP_001701 (OMIM: 138470,612924,615489,615561) comp ( 764) 1849 327.8 1.1e-88
XP_011533056 (OMIM: 608397) PREDICTED: CUB and sus (2238) 360 74.1 7e-12
XP_011533055 (OMIM: 608397) PREDICTED: CUB and sus (2595) 360 74.2 7.8e-12
XP_016869220 (OMIM: 608397) PREDICTED: CUB and sus (3327) 360 74.3 9.2e-12
XP_011533054 (OMIM: 608397) PREDICTED: CUB and sus (3549) 360 74.3 9.6e-12
NP_150094 (OMIM: 608397) CUB and sushi domain-cont (3564) 360 74.3 9.6e-12
XP_016855679 (OMIM: 608398) PREDICTED: CUB and sus (3362) 341 71.1 8.8e-11
XP_016855678 (OMIM: 608398) PREDICTED: CUB and sus (3506) 341 71.1 9e-11
XP_016855683 (OMIM: 608398) PREDICTED: CUB and sus (3566) 341 71.1 9.1e-11
XP_016855677 (OMIM: 608398) PREDICTED: CUB and sus (3567) 341 71.1 9.1e-11
XP_016855676 (OMIM: 608398) PREDICTED: CUB and sus (3606) 341 71.1 9.2e-11
XP_016855675 (OMIM: 608398) PREDICTED: CUB and sus (3607) 341 71.1 9.2e-11
XP_016855674 (OMIM: 608398) PREDICTED: CUB and sus (3607) 341 71.1 9.2e-11
NP_001268885 (OMIM: 608398) CUB and sushi domain-c (3631) 341 71.1 9.2e-11
XP_011515117 (OMIM: 608399) PREDICTED: CUB and sus (2173) 323 67.8 5.5e-10
XP_016868501 (OMIM: 608399) PREDICTED: CUB and sus (3463) 323 68.0 7.5e-10
XP_016868500 (OMIM: 608399) PREDICTED: CUB and sus (3507) 323 68.0 7.6e-10
NP_443132 (OMIM: 608399) CUB and sushi domain-cont (3538) 323 68.0 7.6e-10
XP_016868499 (OMIM: 608399) PREDICTED: CUB and sus (3577) 323 68.0 7.7e-10
XP_011515118 (OMIM: 608399) PREDICTED: CUB and sus (3603) 323 68.0 7.7e-10
XP_016868498 (OMIM: 608399) PREDICTED: CUB and sus (3637) 323 68.0 7.8e-10
NP_937757 (OMIM: 608399) CUB and sushi domain-cont (3667) 323 68.0 7.8e-10
XP_016868497 (OMIM: 608399) PREDICTED: CUB and sus (3681) 323 68.0 7.8e-10
NP_937756 (OMIM: 608399) CUB and sushi domain-cont (3707) 323 68.0 7.9e-10
NP_443128 (OMIM: 608398) CUB and sushi domain-cont (3487) 313 66.3 2.5e-09
NP_000441 (OMIM: 131210,145500) E-selectin precurs ( 610) 298 62.9 4.5e-09
XP_011528291 (OMIM: 206200,609862) PREDICTED: tran ( 680) 293 62.1 8.7e-09
NP_001275929 (OMIM: 206200,609862) transmembrane p ( 824) 293 62.2 9.9e-09
XP_005245493 (OMIM: 147050,173610) PREDICTED: P-se ( 830) 273 58.8 1.1e-07
XP_005245492 (OMIM: 147050,173610) PREDICTED: P-se ( 830) 273 58.8 1.1e-07
NP_002996 (OMIM: 147050,173610) P-selectin precurs ( 830) 273 58.8 1.1e-07
XP_011507508 (OMIM: 120650,240500,610927,614699) P ( 969) 260 56.7 5.5e-07
NP_000033 (OMIM: 138700) beta-2-glycoprotein 1 pre ( 345) 254 55.2 5.5e-07
NP_001868 (OMIM: 120650,240500,610927,614699) comp (1033) 260 56.7 5.7e-07
NP_001006659 (OMIM: 120650,240500,610927,614699) c (1092) 260 56.7 5.9e-07
XP_005245497 (OMIM: 147050,173610) PREDICTED: P-se ( 768) 246 54.2 2.4e-06
NP_000564 (OMIM: 120620,607486,611162) complement (2039) 247 54.8 4.2e-06
XP_006711229 (OMIM: 120620,607486,611162) PREDICTE (2459) 247 54.9 4.8e-06
NP_000642 (OMIM: 120620,607486,611162) complement (2489) 247 54.9 4.8e-06
XP_011507507 (OMIM: 120620,607486,611162) PREDICTE (2554) 247 54.9 4.9e-06
NP_699197 (OMIM: 611691) sushi, von Willebrand fac (3571) 246 54.9 7e-06
XP_016882221 (OMIM: 142440) PREDICTED: serine prot ( 393) 232 51.5 8.1e-06
XP_005258895 (OMIM: 142440) PREDICTED: serine prot ( 417) 232 51.5 8.5e-06
NP_002142 (OMIM: 142440) serine protease hepsin pr ( 417) 232 51.5 8.5e-06
>>NP_000054 (OMIM: 217000,613927,615489) complement C2 i (752 aa)
initn: 5174 init1: 5174 opt: 5174 Z-score: 4780.7 bits: 895.3 E(85289): 0
Smith-Waterman score: 5174; 100.0% identity (100.0% similar) in 752 aa overlap (1-752:1-752)
10 20 30 40 50 60
pF1KE2 MGPLMVLFCLLFLYPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGPLMVLFCLLFLYPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 FILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIITFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIITFAS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 EPKVLMSVLNDNSRDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EPKVLMSVLNDNSRDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGME
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMAWQEIRHAIILLTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLDVDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TMAWQEIRHAIILLTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLDVDW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 RELNELGSKKDGERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RELNELGSKKDGERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 HVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 RDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 DQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRS
670 680 690 700 710 720
730 740 750
pF1KE2 KVPPPRDFHINLFRMQPWLRQHLGDVLNFLPL
::::::::::::::::::::::::::::::::
NP_000 KVPPPRDFHINLFRMQPWLRQHLGDVLNFLPL
730 740 750
>>NP_001269387 (OMIM: 217000,613927,615489) complement C (723 aa)
initn: 4559 init1: 4559 opt: 4561 Z-score: 4215.5 bits: 790.6 E(85289): 0
Smith-Waterman score: 4572; 94.8% identity (95.8% similar) in 714 aa overlap (57-752:10-723)
30 40 50 60 70
pF1KE2 NVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPASRLCK-----------SSGQWQTP--
:.:: : : .::. : :
NP_001 MAGLLGAFSPTPAPRACTHPQHHGCARAADSGRPQEPPG
10 20 30
80 90 100 110 120
pF1KE2 -----GATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPV
.:. : . . ::::::::::::::::::::::::::::::::::::::::::
NP_001 LCLRRSANVRLPVGFAQAVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 RQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSE
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 RECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGRKIQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGRKIQIQ
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 RSGHLNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSGHLNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE2 LNDNSRDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNDNSRDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIR
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE2 HAIILLTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLDVDWRELNELGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAIILLTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLDVDWRELNELGS
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE2 KKDGERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKDGERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE2 QETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFA
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE2 KKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELL
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE2 NKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGT
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE2 QEDESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDF
640 650 660 670 680 690
730 740 750
pF1KE2 HINLFRMQPWLRQHLGDVLNFLPL
::::::::::::::::::::::::
NP_001 HINLFRMQPWLRQHLGDVLNFLPL
700 710 720
>>NP_001139375 (OMIM: 217000,613927,615489) complement C (620 aa)
initn: 4199 init1: 4104 opt: 4104 Z-score: 3794.7 bits: 712.6 E(85289): 1.2e-204
Smith-Waterman score: 4104; 100.0% identity (100.0% similar) in 605 aa overlap (148-752:16-620)
120 130 140 150 160 170
pF1KE2 EDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRC
::::::::::::::::::::::::::::::
NP_001 MGPLMVLFCLLFLYPAGHCPNPGISLGAVRTGFRFGHGDKVRYRC
10 20 30 40
180 190 200 210 220 230
pF1KE2 SSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKT
50 60 70 80 90 100
240 250 260 270 280 290
pF1KE2 KESLGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KESLGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIIT
110 120 130 140 150 160
300 310 320 330 340 350
pF1KE2 FASEPKVLMSVLNDNSRDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FASEPKVLMSVLNDNSRDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLL
170 180 190 200 210 220
360 370 380 390 400 410
pF1KE2 GMETMAWQEIRHAIILLTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMETMAWQEIRHAIILLTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLD
230 240 250 260 270 280
420 430 440 450 460 470
pF1KE2 VDWRELNELGSKKDGERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDWRELNELGSKKDGERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQER
290 300 310 320 330 340
480 490 500 510 520 530
pF1KE2 TPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEK
350 360 370 380 390 400
540 550 560 570 580 590
pF1KE2 AVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQG
410 420 430 440 450 460
600 610 620 630 640 650
pF1KE2 STCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVRE
470 480 490 500 510 520
660 670 680 690 700 710
pF1KE2 VVTDQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVTDQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRA
530 540 550 560 570 580
720 730 740 750
pF1KE2 PRSKVPPPRDFHINLFRMQPWLRQHLGDVLNFLPL
:::::::::::::::::::::::::::::::::::
NP_001 PRSKVPPPRDFHINLFRMQPWLRQHLGDVLNFLPL
590 600 610 620
>>NP_001269386 (OMIM: 217000,613927,615489) complement C (506 aa)
initn: 3171 init1: 3171 opt: 3171 Z-score: 2935.2 bits: 553.2 E(85289): 9.4e-157
Smith-Waterman score: 3171; 100.0% identity (100.0% similar) in 469 aa overlap (284-752:38-506)
260 270 280 290 300 310
pF1KE2 NLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSVLNDNS
::::::::::::::::::::::::::::::
NP_001 AAPRILCSRGLRSGSARATGSGVERSPSAAIFSFEINVSVAIITFASEPKVLMSVLNDNS
10 20 30 40 50 60
320 330 340 350 360 370
pF1KE2 RDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIRHAIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIRHAIIL
70 80 90 100 110 120
380 390 400 410 420 430
pF1KE2 LTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLDVDWRELNELGSKKDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLDVDWRELNELGSKKDGE
130 140 150 160 170 180
440 450 460 470 480 490
pF1KE2 RHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETCR
190 200 210 220 230 240
500 510 520 530 540 550
pF1KE2 GALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQG
250 260 270 280 290 300
560 570 580 590 600 610
pF1KE2 ILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSV
310 320 330 340 350 360
620 630 640 650 660 670
pF1KE2 PAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDES
370 380 390 400 410 420
680 690 700 710 720 730
pF1KE2 PCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINLF
430 440 450 460 470 480
740 750
pF1KE2 RMQPWLRQHLGDVLNFLPL
:::::::::::::::::::
NP_001 RMQPWLRQHLGDVLNFLPL
490 500
>>NP_001171534 (OMIM: 217000,613927,615489) complement C (538 aa)
initn: 2902 init1: 2902 opt: 2902 Z-score: 2686.7 bits: 507.3 E(85289): 6.5e-143
Smith-Waterman score: 3352; 85.0% identity (85.0% similar) in 605 aa overlap (148-752:25-538)
120 130 140 150 160 170
pF1KE2 EDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRC
::::::::::::::::::::::::::::::
NP_001 MRALCIRETCSSELGFSRNWSRRKAGHCPNPGISLGAVRTGFRFGHGDKVRYRC
10 20 30 40 50
180 190 200 210 220 230
pF1KE2 SSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKT
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE2 KESLGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIIT
:
NP_001 K-----------------------------------------------------------
300 310 320 330 340 350
pF1KE2 FASEPKVLMSVLNDNSRDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLL
::::::::::::::::::::::::::::
NP_001 --------------------------------DHENGTGTNTYAALNSVYLMMNNQMRLL
120 130 140
360 370 380 390 400 410
pF1KE2 GMETMAWQEIRHAIILLTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMETMAWQEIRHAIILLTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLD
150 160 170 180 190 200
420 430 440 450 460 470
pF1KE2 VDWRELNELGSKKDGERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDWRELNELGSKKDGERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQER
210 220 230 240 250 260
480 490 500 510 520 530
pF1KE2 TPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEK
270 280 290 300 310 320
540 550 560 570 580 590
pF1KE2 AVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQG
330 340 350 360 370 380
600 610 620 630 640 650
pF1KE2 STCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVRE
390 400 410 420 430 440
660 670 680 690 700 710
pF1KE2 VVTDQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVTDQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRA
450 460 470 480 490 500
720 730 740 750
pF1KE2 PRSKVPPPRDFHINLFRMQPWLRQHLGDVLNFLPL
:::::::::::::::::::::::::::::::::::
NP_001 PRSKVPPPRDFHINLFRMQPWLRQHLGDVLNFLPL
510 520 530
>>NP_001269388 (OMIM: 217000,613927,615489) complement C (328 aa)
initn: 2007 init1: 2007 opt: 2007 Z-score: 1863.7 bits: 354.3 E(85289): 4.5e-97
Smith-Waterman score: 2009; 88.4% identity (93.3% similar) in 328 aa overlap (1-316:1-328)
10 20 30 40 50 60
pF1KE2 MGPLMVLFCLLFLYPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGPLMVLFCLLFLYPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 FILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKES
190 200 210 220 230 240
250 260 270 280 290
pF1KE2 LGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFE---------INV
:::::::::::::::::::::::::::::::::::::::::::. . : ...
NP_001 LGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLMVDRVRNQESACSRGLPVLTI
250 260 270 280 290 300
300 310 320 330 340
pF1KE2 SVAIITFASEP---KVLMSVLNDNSRDMTEVISSLENANYKDHENGTGTNTYAALNSVYL
:. .. . : ..:. :..: .. :
NP_001 SLCLLPLLRTPLTAHLLQEVFSDYTHAM
310 320
>>NP_001701 (OMIM: 138470,612924,615489,615561) compleme (764 aa)
initn: 1524 init1: 548 opt: 1849 Z-score: 1713.5 bits: 327.8 E(85289): 1.1e-88
Smith-Waterman score: 1849; 39.8% identity (69.6% similar) in 757 aa overlap (17-750:30-764)
10 20 30 40
pF1KE2 MGPLMVLFCLLFLYPGLADSAPSCP-QNVNISGGTFTLSHGWAPGSL
:: :: ..:.:.::.: : . :.
NP_001 MGSNLSPQLCLMPFILGLLSGGVTTTPWSLARPQGSCSLEGVEIKGGSFRLLQ---EGQA
10 20 30 40 50
50 60 70 80 90 100
pF1KE2 LTYSCPQGLYPSPA-SRLCKSSGQWQT--PGATRSLSKAVCKPVRCPAPVSFENGIYTPR
: : ::.:.:: :. .: :.:.:.:.: ... :: :. ..:: : .:::: : ::
NP_001 LEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPR
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE2 LGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRT
: :. ..::.: ::. :::: : :. :: :.:.::.::::::.: :::: .:. ..
NP_001 SPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKV
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 GFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTS
: .. :.: :.:: .:.: ::..: :: .: :::::: :.. . :: :..:: :. .:
NP_001 GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAEAFLSS
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 FSHMLGATNPT--QKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLMV
... . ... . :. ::: .. :: .:.::.:: :.:.. ..: :. ..
NP_001 LTETIEGVDAEDGHGPGEQQKRKIVLDPSGSMNIYLVLDGSDSIGASNFTGAKKCLVNLI
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE2 DRIFSFEINVSVAIITFASEPKVLMSVLNDNSRDMTEVISSLENANYKDHENGTGTNTYA
... :. .. ...:.:. ::. ..: . .: . : ..:.. ::.::. .::::
NP_001 EKVASYGVKPRYGLVTYATYPKIWVKVSEADSSNADWVTKQLNEINYEDHKLKSGTNTKK
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE2 ALNSVYLMMNNQMRLLGMETMAWQEIRHAIILLTDGKSNMGGSPKTAVDHIREILNINQK
::..:: ::. . .:.. ::.:::.::: ::::.: :..:.::..: :..
NP_001 ALQAVYSMMSWPD---DVPPEGWNRTRHVIILMTDGLHNMGGDPITVIDEIRDLLYIGKD
360 370 380 390 400 410
410 420 430 440 450
pF1KE2 RN----DYLDIYAIGVGKLDVDWRELNELGSKKDGERHAFILQDTKALHQVFEHMLDVSK
:. ::::.:..::: : :. ..: :.::::.:.:.: ..: . :..:: .:.: :.
NP_001 RKNPREDYLDVYVFGVGPL-VNQVNINALASKKDNEQHVFKVKDMENLEDVFYQMIDESQ
420 430 440 450 460 470
460 470 480 490 500 510
pF1KE2 LTDTICGVGNMSANASDQERTPWHV---TIKP-KSQETCRGALISDQWVLTAAHCFR-DG
. ..::. ...: .. ::.. .:.: :..:.: ::..:. .:::::::: :
NP_001 -SLSLCGMVWEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDD
480 490 500 510 520 530
520 530 540 550 560 570
pF1KE2 NDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVK
..::. .:.:: : ... :: ... :.... .::. :: ::: :.::.:: .:.:
NP_001 KEHSI-KVSVGGEK----RDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLK
540 550 560 570 580
580 590 600 610 620
pF1KE2 MSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLN---INL
.. :::::::: .. ::: : .::.....::: :.. : ::. . .::. . .
NP_001 YGQTIRPICLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYI
590 600 610 620 630 640
630 640 650 660 670 680
pF1KE2 KMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSG---TQEDESPCKGESGGAVFLE
: : . :: : .: . .. :. :::: .:::.: : . :.:.::: ....
NP_001 KNGDKKGSC-ERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVH
650 660 670 680 690 700
690 700 710 720 730 740
pF1KE2 RRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPP-PRDFHINLFRMQPWLRQHLGD
.: ::.:::..:::. . : ::... ...:: ::::::::.. :::...: :
NP_001 KRSRFIQVGVISWGVVDVC-----KNQKR---QKQVPAHARDFHINLFQVLPWLKEKLQD
710 720 730 740 750
750
pF1KE2 V-LNFLPL
:.::
NP_001 EDLGFL
760
>>XP_011533056 (OMIM: 608397) PREDICTED: CUB and sushi d (2238 aa)
initn: 352 init1: 194 opt: 360 Z-score: 334.3 bits: 74.1 E(85289): 7e-12
Smith-Waterman score: 380; 31.7% identity (56.2% similar) in 224 aa overlap (20-231:1702-1912)
10 20 30 40
pF1KE2 MGPLMVLFCLLFLYPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLLT-
.::.: .. : ::..: :. .:
XP_011 SSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDC--TIISCGDPGTLANGIQFGTDFTF
1680 1690 1700 1710 1720
50 60 70 80 90 100
pF1KE2 -----YSCPQGLYP---SPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIY
:.: : . :. : ..:.:. : :: ::: : :: : .::
XP_011 NKTVSYQCNPGYVMEAVTSATIRCTKDGRWN-P------SKPVCKAVLCPQPPPVQNG--
1730 1740 1750 1760 1770 1780
110 120 130 140 150 160
pF1KE2 TPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGA
: . ... :...:. : ::. : : . .:. :.: :: : : .::: .
XP_011 TVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCL--PVFCGDPGIPAEG
1790 1800 1810 1820 1830
170 180 190 200 210 220
pF1KE2 VRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPAL
.: : . ..: ..:.: ..:.:::.: ::..:.::: .: : .: :. .: .
XP_011 RLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHF
1840 1850 1860 1870 1880 1890
230 240 250 260 270
pF1KE2 G---TSFSHMLGATNPTQKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESA
: .: .. .:.:
XP_011 GIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHA
1900 1910 1920 1930 1940 1950
>--
initn: 341 init1: 151 opt: 335 Z-score: 311.2 bits: 69.8 E(85289): 1.4e-10
Smith-Waterman score: 335; 32.5% identity (53.6% similar) in 194 aa overlap (22-204:1405-1586)
10 20 30 40
pF1KE2 MGPLMVLFCLLFLYPGLADSAPSC-PQNVNISGGTFTLSHGWAPGS-----
: : : . . :. .::.. ::
XP_011 TVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNP---AHGFTNGSEFNLN
1380 1390 1400 1410 1420 1430
50 60 70 80 90 100
pF1KE2 -LLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPR
.....: : . .:: :.:.:::..: : :. : : : ::.: .
XP_011 DVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPT-------CRVVNCSDPGFVENAIRHGQ
1440 1450 1460 1470 1480
110 120 130 140 150 160
pF1KE2 LG---SYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGA
. :. : .. ..:. :: : :: . : ::.:: : : : .::. .:
XP_011 QNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKC--LAISCGHPGVPANA
1490 1500 1510 1520 1530 1540
170 180 190 200 210 220
pF1KE2 VRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPAL
: :: : .: :.: : .. : :.. : :: .. :::. : :
XP_011 VLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAH
1550 1560 1570 1580 1590 1600
230 240 250 260 270 280
pF1KE2 GTSFSHMLGATNPTQKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLM
XP_011 GSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGM
1610 1620 1630 1640 1650 1660
>--
initn: 220 init1: 144 opt: 278 Z-score: 258.6 bits: 60.1 E(85289): 1.1e-07
Smith-Waterman score: 278; 33.3% identity (55.3% similar) in 159 aa overlap (44-199:1255-1402)
20 30 40 50 60 70
pF1KE2 YPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPASRL-CKSSGQWQT
:. . :: : : : :...: :.
XP_011 TCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNI
1230 1240 1250 1260 1270 1280
80 90 100 110 120 130
pF1KE2 PGATRSLSKAVCKPVRCPAPVSFE-NGIYTPRLGSYPVGGNVS-FECEDGFILRGSPVRQ
: : :. . : . .:: :: ..:. : : .. : :. :. : :: ::.
XP_011 -GDERP----SCRVISCGS-LSFPPNG---NKIGTLTVYGATAIFTCNTGYTLVGSHVRE
1290 1300 1310 1320 1330
140 150 160 170 180 190
pF1KE2 CRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERE
: ::.:.: . : :::: .: ... .: :.. : : :.:. .. :.:.: :
XP_011 CLANGLWSGSETRCL--AGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRI
1340 1350 1360 1370 1380 1390
200 210 220 230 240 250
pF1KE2 CQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGRKIQIQRS
: . :::
XP_011 CLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCR
1400 1410 1420 1430 1440 1450
>>XP_011533055 (OMIM: 608397) PREDICTED: CUB and sushi d (2595 aa)
initn: 439 init1: 165 opt: 360 Z-score: 333.5 bits: 74.2 E(85289): 7.8e-12
Smith-Waterman score: 380; 31.7% identity (56.2% similar) in 224 aa overlap (20-231:2059-2269)
10 20 30 40
pF1KE2 MGPLMVLFCLLFLYPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLLT-
.::.: .. : ::..: :. .:
XP_011 SSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDC--TIISCGDPGTLANGIQFGTDFTF
2030 2040 2050 2060 2070 2080
50 60 70 80 90 100
pF1KE2 -----YSCPQGLYP---SPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIY
:.: : . :. : ..:.:. : :: ::: : :: : .::
XP_011 NKTVSYQCNPGYVMEAVTSATIRCTKDGRWN-P------SKPVCKAVLCPQPPPVQNG--
2090 2100 2110 2120 2130
110 120 130 140 150 160
pF1KE2 TPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGA
: . ... :...:. : ::. : : . .:. :.: :: : : .::: .
XP_011 TVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCL--PVFCGDPGIPAEG
2140 2150 2160 2170 2180 2190
170 180 190 200 210 220
pF1KE2 VRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPAL
.: : . ..: ..:.: ..:.:::.: ::..:.::: .: : .: :. .: .
XP_011 RLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHF
2200 2210 2220 2230 2240 2250
230 240 250 260 270
pF1KE2 G---TSFSHMLGATNPTQKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESA
: .: .. .:.:
XP_011 GIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHA
2260 2270 2280 2290 2300 2310
>--
initn: 288 init1: 151 opt: 335 Z-score: 310.4 bits: 69.9 E(85289): 1.5e-10
Smith-Waterman score: 335; 32.5% identity (53.6% similar) in 194 aa overlap (22-204:1762-1943)
10 20 30 40
pF1KE2 MGPLMVLFCLLFLYPGLADSAPSC-PQNVNISGGTFTLSHGWAPGS-----
: : : . . :. .::.. ::
XP_011 TVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNP---AHGFTNGSEFNLN
1740 1750 1760 1770 1780
50 60 70 80 90 100
pF1KE2 -LLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPR
.....: : . .:: :.:.:::..: : :. : : : ::.: .
XP_011 DVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPT-------CRVVNCSDPGFVENAIRHGQ
1790 1800 1810 1820 1830 1840
110 120 130 140 150 160
pF1KE2 LG---SYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGA
. :. : .. ..:. :: : :: . : ::.:: : : : .::. .:
XP_011 QNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKC--LAISCGHPGVPANA
1850 1860 1870 1880 1890
170 180 190 200 210 220
pF1KE2 VRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPAL
: :: : .: :.: : .. : :.. : :: .. :::. : :
XP_011 VLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAH
1900 1910 1920 1930 1940 1950
230 240 250 260 270 280
pF1KE2 GTSFSHMLGATNPTQKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLM
XP_011 GSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGM
1960 1970 1980 1990 2000 2010
>--
initn: 220 init1: 144 opt: 278 Z-score: 257.8 bits: 60.2 E(85289): 1.3e-07
Smith-Waterman score: 278; 33.3% identity (55.3% similar) in 159 aa overlap (44-199:1612-1759)
20 30 40 50 60 70
pF1KE2 YPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPASRL-CKSSGQWQT
:. . :: : : : :...: :.
XP_011 TCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNI
1590 1600 1610 1620 1630 1640
80 90 100 110 120 130
pF1KE2 PGATRSLSKAVCKPVRCPAPVSFE-NGIYTPRLGSYPVGGNVS-FECEDGFILRGSPVRQ
: : :. . : . .:: :: ..:. : : .. : :. :. : :: ::.
XP_011 -GDERP----SCRVISCGS-LSFPPNG---NKIGTLTVYGATAIFTCNTGYTLVGSHVRE
1650 1660 1670 1680 1690
140 150 160 170 180 190
pF1KE2 CRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERE
: ::.:.: . : :::: .: ... .: :.. : : :.:. .. :.:.: :
XP_011 CLANGLWSGSETRCL--AGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRI
1700 1710 1720 1730 1740 1750
200 210 220 230 240 250
pF1KE2 CQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGRKIQIQRS
: . :::
XP_011 CLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCR
1760 1770 1780 1790 1800 1810
>>XP_016869220 (OMIM: 608397) PREDICTED: CUB and sushi d (3327 aa)
initn: 597 init1: 165 opt: 360 Z-score: 332.2 bits: 74.3 E(85289): 9.2e-12
Smith-Waterman score: 380; 31.7% identity (56.2% similar) in 224 aa overlap (20-231:3028-3238)
10 20 30 40
pF1KE2 MGPLMVLFCLLFLYPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLLT-
.::.: .. : ::..: :. .:
XP_016 SSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDC--TIISCGDPGTLANGIQFGTDFTF
3000 3010 3020 3030 3040 3050
50 60 70 80 90 100
pF1KE2 -----YSCPQGLYP---SPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIY
:.: : . :. : ..:.:. : :: ::: : :: : .::
XP_016 NKTVSYQCNPGYVMEAVTSATIRCTKDGRWN-P------SKPVCKAVLCPQPPPVQNG--
3060 3070 3080 3090 3100
110 120 130 140 150 160
pF1KE2 TPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGA
: . ... :...:. : ::. : : . .:. :.: :: : : .::: .
XP_016 TVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCL--PVFCGDPGIPAEG
3110 3120 3130 3140 3150 3160
170 180 190 200 210 220
pF1KE2 VRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPAL
.: : . ..: ..:.: ..:.:::.: ::..:.::: .: : .: :. .: .
XP_016 RLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHF
3170 3180 3190 3200 3210 3220
230 240 250 260 270
pF1KE2 G---TSFSHMLGATNPTQKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESA
: .: .. .:.:
XP_016 GIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECILWFPRTGSITIGW
3230 3240 3250 3260 3270 3280
>--
initn: 446 init1: 151 opt: 335 Z-score: 309.1 bits: 70.0 E(85289): 1.8e-10
Smith-Waterman score: 335; 32.5% identity (53.6% similar) in 194 aa overlap (22-204:2731-2912)
10 20 30 40
pF1KE2 MGPLMVLFCLLFLYPGLADSAPSC-PQNVNISGGTFTLSHGWAPGS-----
: : : . . :. .::.. ::
XP_016 TVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNP---AHGFTNGSEFNLN
2710 2720 2730 2740 2750
50 60 70 80 90 100
pF1KE2 -LLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPR
.....: : . .:: :.:.:::..: : :. : : : ::.: .
XP_016 DVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPT-------CRVVNCSDPGFVENAIRHGQ
2760 2770 2780 2790 2800 2810
110 120 130 140 150 160
pF1KE2 LG---SYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGA
. :. : .. ..:. :: : :: . : ::.:: : : : .::. .:
XP_016 QNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKC--LAISCGHPGVPANA
2820 2830 2840 2850 2860
170 180 190 200 210 220
pF1KE2 VRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPAL
: :: : .: :.: : .. : :.. : :: .. :::. : :
XP_016 VLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAH
2870 2880 2890 2900 2910 2920
230 240 250 260 270 280
pF1KE2 GTSFSHMLGATNPTQKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLM
XP_016 GSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGM
2930 2940 2950 2960 2970 2980
752 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 20:30:55 2016 done: Sun Nov 6 20:30:56 2016
Total Scan time: 8.790 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]