Result of FASTA (omim) for
pFN21AE2064
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2064, 712 aa
1>>>pF1KE2064 712 - 712 aa - 712 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4891+/-0.000394; mu= 9.4699+/- 0.025
mean_var=133.8047+/-25.626, 0's: 0 Z-trim(116.8): 209 B-trim: 314 in 1/56
Lambda= 0.110876
statistics sampled from 28117 (28343) to 28117 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.684), E-opt: 0.2 (0.332), width: 16
Scan time: 12.840
The best scores are: opt bits E(85289)
NP_001317101 (OMIM: 600128) cAMP-specific 3',5'-cy ( 712) 4716 766.4 0
NP_000914 (OMIM: 600128) cAMP-specific 3',5'-cycli ( 712) 4716 766.4 0
NP_001092288 (OMIM: 600128) cAMP-specific 3',5'-cy ( 680) 4139 674.1 5.1e-193
NP_001092289 (OMIM: 600128) cAMP-specific 3',5'-cy ( 606) 3963 645.9 1.4e-184
XP_011526358 (OMIM: 600128) PREDICTED: cAMP-specif ( 606) 3963 645.9 1.4e-184
XP_011526360 (OMIM: 600128) PREDICTED: cAMP-specif ( 481) 3142 514.5 3.9e-145
NP_001098101 (OMIM: 600129,606799,614613) cAMP-spe ( 809) 3105 508.7 3.6e-143
NP_001184148 (OMIM: 600129,606799,614613) cAMP-spe ( 687) 3052 500.2 1.1e-140
XP_016865058 (OMIM: 600129,606799,614613) PREDICTE ( 699) 3045 499.1 2.5e-140
XP_005248594 (OMIM: 600129,606799,614613) PREDICTE ( 699) 3045 499.1 2.5e-140
XP_005248595 (OMIM: 600129,606799,614613) PREDICTE ( 673) 3035 497.5 7.3e-140
NP_006194 (OMIM: 600129,606799,614613) cAMP-specif ( 673) 3035 497.5 7.3e-140
NP_001184149 (OMIM: 600129,606799,614613) cAMP-spe ( 679) 3035 497.5 7.3e-140
NP_001184147 (OMIM: 600129,606799,614613) cAMP-spe ( 745) 3032 497.0 1.1e-139
XP_011541779 (OMIM: 600129,606799,614613) PREDICTE ( 662) 3031 496.8 1.1e-139
XP_016865057 (OMIM: 600129,606799,614613) PREDICTE ( 738) 3031 496.8 1.2e-139
XP_016865056 (OMIM: 600129,606799,614613) PREDICTE ( 743) 3031 496.8 1.2e-139
NP_001159371 (OMIM: 600129,606799,614613) cAMP-spe ( 748) 3031 496.8 1.2e-139
XP_011541773 (OMIM: 600129,606799,614613) PREDICTE ( 748) 3031 496.8 1.2e-139
XP_016865055 (OMIM: 600129,606799,614613) PREDICTE ( 748) 3031 496.8 1.2e-139
XP_011541775 (OMIM: 600129,606799,614613) PREDICTE ( 748) 3031 496.8 1.2e-139
XP_011541771 (OMIM: 600129,606799,614613) PREDICTE ( 797) 3031 496.9 1.3e-139
XP_016865054 (OMIM: 600129,606799,614613) PREDICTE ( 797) 3031 496.9 1.3e-139
XP_011541772 (OMIM: 600129,606799,614613) PREDICTE ( 797) 3031 496.9 1.3e-139
NP_001032417 (OMIM: 600127) cAMP-specific 3',5'-cy ( 721) 2858 469.2 2.6e-131
NP_001284370 (OMIM: 600127) cAMP-specific 3',5'-cy ( 661) 2825 463.9 9.3e-130
NP_001284369 (OMIM: 600127) cAMP-specific 3',5'-cy ( 644) 2823 463.5 1.1e-129
NP_002591 (OMIM: 600127) cAMP-specific 3',5'-cycli ( 736) 2823 463.6 1.3e-129
NP_001032418 (OMIM: 600127) cAMP-specific 3',5'-cy ( 736) 2823 463.6 1.3e-129
NP_001184151 (OMIM: 600129,606799,614613) cAMP-spe ( 585) 2564 422.1 3.1e-117
XP_016865060 (OMIM: 600129,606799,614613) PREDICTE ( 553) 2560 421.4 4.6e-117
XP_016865059 (OMIM: 600129,606799,614613) PREDICTE ( 553) 2560 421.4 4.6e-117
XP_016856934 (OMIM: 600127) PREDICTED: cAMP-specif ( 597) 2550 419.8 1.5e-116
NP_001032416 (OMIM: 600127) cAMP-specific 3',5'-cy ( 564) 2418 398.7 3.2e-110
XP_006710743 (OMIM: 600127) PREDICTED: cAMP-specif ( 531) 2412 397.7 6e-110
XP_016856935 (OMIM: 600127) PREDICTED: cAMP-specif ( 530) 2402 396.1 1.8e-109
XP_011539868 (OMIM: 600127) PREDICTED: cAMP-specif ( 530) 2402 396.1 1.8e-109
XP_005270981 (OMIM: 600127) PREDICTED: cAMP-specif ( 517) 2377 392.1 2.8e-108
XP_005270982 (OMIM: 600127) PREDICTED: cAMP-specif ( 517) 2377 392.1 2.8e-108
NP_001184150 (OMIM: 600129,606799,614613) cAMP-spe ( 507) 2374 391.7 3.9e-108
NP_001184152 (OMIM: 600129,606799,614613) cAMP-spe ( 518) 2350 387.8 5.7e-107
NP_001284371 (OMIM: 600127) cAMP-specific 3',5'-cy ( 503) 2220 367.0 1e-100
NP_006193 (OMIM: 600126) cAMP-specific 3',5'-cycli ( 647) 2071 343.2 1.8e-93
XP_005259990 (OMIM: 600126) PREDICTED: cAMP-specif ( 582) 2070 343.1 1.9e-93
NP_001104779 (OMIM: 600126) cAMP-specific 3',5'-cy ( 825) 2070 343.1 2.5e-93
NP_001104778 (OMIM: 600126) cAMP-specific 3',5'-cy ( 860) 2070 343.2 2.6e-93
XP_011526356 (OMIM: 600126) PREDICTED: cAMP-specif ( 864) 2070 343.2 2.6e-93
NP_001230050 (OMIM: 600126) cAMP-specific 3',5'-cy ( 864) 2070 343.2 2.6e-93
XP_016882354 (OMIM: 600126) PREDICTED: cAMP-specif ( 885) 2070 343.2 2.7e-93
NP_001104777 (OMIM: 600126) cAMP-specific 3',5'-cy ( 886) 2070 343.2 2.7e-93
>>NP_001317101 (OMIM: 600128) cAMP-specific 3',5'-cyclic (712 aa)
initn: 4716 init1: 4716 opt: 4716 Z-score: 4084.9 bits: 766.4 E(85289): 0
Smith-Waterman score: 4716; 100.0% identity (100.0% similar) in 712 aa overlap (1-712:1-712)
10 20 30 40 50 60
pF1KE2 MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LSPRPELRKSRLSWPVSSCRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSPRPELRKSRLSWPVSSCRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 AKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 ALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 IDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFEL
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 TLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
670 680 690 700 710
>>NP_000914 (OMIM: 600128) cAMP-specific 3',5'-cyclic ph (712 aa)
initn: 4716 init1: 4716 opt: 4716 Z-score: 4084.9 bits: 766.4 E(85289): 0
Smith-Waterman score: 4716; 100.0% identity (100.0% similar) in 712 aa overlap (1-712:1-712)
10 20 30 40 50 60
pF1KE2 MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LSPRPELRKSRLSWPVSSCRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSPRPELRKSRLSWPVSSCRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 AKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 ALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 IDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFEL
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 TLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
670 680 690 700 710
>>NP_001092288 (OMIM: 600128) cAMP-specific 3',5'-cyclic (680 aa)
initn: 4138 init1: 4138 opt: 4139 Z-score: 3586.3 bits: 674.1 E(85289): 5.1e-193
Smith-Waterman score: 4139; 98.3% identity (98.9% similar) in 645 aa overlap (68-712:40-680)
40 50 60 70 80 90
pF1KE2 RPIRIQQRFYSDPDKSAGCRERDLSPRPELRKSRLSWPVSSCRRFDLENGLSCGRRALDP
:. .. :. : ::::::::::::::::
NP_001 VPGPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPL--C--FDLENGLSCGRRALDP
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE2 QSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQ
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE2 VLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCL
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE2 DQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPK
190 200 210 220 230 240
280 290 300 310 320 330
pF1KE2 VTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKV
250 260 270 280 290 300
340 350 360 370 380 390
pF1KE2 AELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVA
310 320 330 340 350 360
400 410 420 430 440 450
pF1KE2 QSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVL
370 380 390 400 410 420
460 470 480 490 500 510
pF1KE2 ENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVET
430 440 450 460 470 480
520 530 540 550 560 570
pF1KE2 KKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERE
490 500 510 520 530 540
580 590 600 610 620 630
pF1KE2 SGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSK
550 560 570 580 590 600
640 650 660 670 680 690
pF1KE2 IPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPE
610 620 630 640 650 660
700 710
pF1KE2 AGPDPGDLPLDNQRT
:::::::::::::::
NP_001 AGPDPGDLPLDNQRT
670 680
>>NP_001092289 (OMIM: 600128) cAMP-specific 3',5'-cyclic (606 aa)
initn: 3963 init1: 3963 opt: 3963 Z-score: 3434.9 bits: 645.9 E(85289): 1.4e-184
Smith-Waterman score: 3963; 100.0% identity (100.0% similar) in 606 aa overlap (107-712:1-606)
80 90 100 110 120 130
pF1KE2 SSCRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMS
::::::::::::::::::::::::::::::
NP_001 MQAPVPHSQRRESFLYRSDSDYELSPKAMS
10 20 30
140 150 160 170 180 190
pF1KE2 RNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLP
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 PAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGN
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE2 QVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQ
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE2 EEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLM
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE2 LEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVS
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE2 NQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMV
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE2 LATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPL
400 410 420 430 440 450
560 570 580 590 600 610
pF1KE2 YRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLV
460 470 480 490 500 510
620 630 640 650 660 670
pF1KE2 HPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEG
520 530 540 550 560 570
680 690 700 710
pF1KE2 EETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
::::::::::::::::::::::::::::::::::::
NP_001 EETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
580 590 600
>>XP_011526358 (OMIM: 600128) PREDICTED: cAMP-specific 3 (606 aa)
initn: 3963 init1: 3963 opt: 3963 Z-score: 3434.9 bits: 645.9 E(85289): 1.4e-184
Smith-Waterman score: 3963; 100.0% identity (100.0% similar) in 606 aa overlap (107-712:1-606)
80 90 100 110 120 130
pF1KE2 SSCRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMS
::::::::::::::::::::::::::::::
XP_011 MQAPVPHSQRRESFLYRSDSDYELSPKAMS
10 20 30
140 150 160 170 180 190
pF1KE2 RNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLP
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 PAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGN
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE2 QVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQ
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE2 EEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLM
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE2 LEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVS
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE2 NQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMV
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE2 LATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPL
400 410 420 430 440 450
560 570 580 590 600 610
pF1KE2 YRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLV
460 470 480 490 500 510
620 630 640 650 660 670
pF1KE2 HPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEG
520 530 540 550 560 570
680 690 700 710
pF1KE2 EETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
::::::::::::::::::::::::::::::::::::
XP_011 EETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
580 590 600
>>XP_011526360 (OMIM: 600128) PREDICTED: cAMP-specific 3 (481 aa)
initn: 3142 init1: 3142 opt: 3142 Z-score: 2726.7 bits: 514.5 E(85289): 3.9e-145
Smith-Waterman score: 3142; 100.0% identity (100.0% similar) in 481 aa overlap (232-712:1-481)
210 220 230 240 250 260
pF1KE2 GQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEY
::::::::::::::::::::::::::::::
XP_011 MASNKFKRILNRELTHLSETSRSGNQVSEY
10 20 30
270 280 290 300 310 320
pF1KE2 ISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLA
40 50 60 70 80 90
330 340 350 360 370 380
pF1KE2 KELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHY
100 110 120 130 140 150
390 400 410 420 430 440
pF1KE2 HANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLI
160 170 180 190 200 210
450 460 470 480 490 500
pF1KE2 NTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDM
220 230 240 250 260 270
510 520 530 540 550 560
pF1KE2 SKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWT
280 290 300 310 320 330
570 580 590 600 610 620
pF1KE2 DRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQ
340 350 360 370 380 390
630 640 650 660 670 680
pF1KE2 DLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETAL
400 410 420 430 440 450
690 700 710
pF1KE2 AKEALELPDTELLSPEAGPDPGDLPLDNQRT
:::::::::::::::::::::::::::::::
XP_011 AKEALELPDTELLSPEAGPDPGDLPLDNQRT
460 470 480
>>NP_001098101 (OMIM: 600129,606799,614613) cAMP-specifi (809 aa)
initn: 3214 init1: 2084 opt: 3105 Z-score: 2691.3 bits: 508.7 E(85289): 3.6e-143
Smith-Waterman score: 3138; 71.3% identity (85.3% similar) in 686 aa overlap (41-710:103-783)
20 30 40 50 60
pF1KE2 EACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERDLSP-------
:...: ::: .. :: : .
NP_001 LQPPPPPPLPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGH
80 90 100 110 120 130
70 80 90 100 110 120
pF1KE2 RPELRKSRLSWPVS--SCRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFL
:: :.:::.::: : . ::::..:: : :: :::..::: : :.:: :::::::::
NP_001 RPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFL
140 150 160 170 180 190
130 140 150 160 170 180
pF1KE2 YRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAA
:::::::.::::.::::::.:::.::.:.::::::::::::::::.: :::. : . .
NP_001 YRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPS
200 210 220 230 240 250
190 200 210 220 230 240
pF1KE2 KQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRIL
:..:. : : :. .:.. :::: :::.::::::::::::::::::.:::::::::.:
NP_001 KRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRML
260 270 280 290 300 310
250 260 270 280 290
pF1KE2 NRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ---PMSRISGLHGLCH
::::::::: :::::::::.:: ::::.: :::.:. : .: . :::.:::.. : :
NP_001 NRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMH
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE2 SASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERD
:.::.....:::::.:.::. :::::::.::::: ::..::::::::::.:. .::::::
NP_001 SSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERD
380 390 400 410 420 430
360 370 380 390 400 410
pF1KE2 LLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEI
:::::.::.::: :::. :: ::::.:::::..:::::.:::::::.:::::::::::::
NP_001 LLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEI
440 450 460 470 480 490
420 430 440 450 460 470
pF1KE2 LAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQ
:::.:::::::::::::::::::::::::::::::.:::::::::::::::: :::::::
NP_001 LAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQ
500 510 520 530 540 550
480 490 500 510 520 530
pF1KE2 NLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVL
::. ::: :::.::::.::::::::::::::::::::::::::: :::::::::::::::
NP_001 NLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVL
560 570 580 590 600 610
540 550 560 570 580 590
pF1KE2 QNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQV
::.::::::::::::: :::::::::: :::.::::::: :..::::::::.::::::::
NP_001 QNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQV
620 630 640 650 660 670
600 610 620 630 640 650
pF1KE2 GFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTN-PE--RDGP-D
::::::.:::::::::::::::::.::::::::::::: ::.::: . :: :.: .
NP_001 GFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTE
680 690 700 710 720 730
660 670 680 690 700 710
pF1KE2 RFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
.::::::::: : : :.. : .. .: :.. : . . . ..:::.:
NP_001 KFQFELTLEEDGESDTEKDS-GSQV---EEDTSCSDSKTLCTQDS-ESTEIPLDEQVEEE
740 750 760 770 780
NP_001 AVGEEEESQPEACVIDDRSPDT
790 800
>>NP_001184148 (OMIM: 600129,606799,614613) cAMP-specifi (687 aa)
initn: 3037 init1: 2084 opt: 3052 Z-score: 2646.6 bits: 500.2 E(85289): 1.1e-140
Smith-Waterman score: 3052; 72.7% identity (86.3% similar) in 656 aa overlap (63-710:13-661)
40 50 60 70 80 90
pF1KE2 WRQPRRPIRIQQRFYSDPDKSAGCRERDLSPRPELR-KSRLSWPVSSCRRFDLENGLSCG
: : : :::: . :. ::..:: : :
NP_001 MAFVWDPLGATVPGPSTRAKSRLRF--SKSYSFDVDNGTSAG
10 20 30 40
100 110 120 130 140 150
pF1KE2 RRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMI
: :::..::: : :.:: ::::::::::::::::.::::.::::::.:::.::.:.:
NP_001 RSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLI
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE2 VTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLD
:::::::::::::::.: :::. : . .:..:. : : :. .:.. :::: :::.
NP_001 VTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE2 ELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQT
::::::::::::::::::.:::::::::.:::::::::: :::::::::.:: ::::.:
NP_001 ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQH
170 180 190 200 210 220
280 290 300 310 320
pF1KE2 EVELPKVTAEEAPQ---PMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTN
:::.:. : .: . :::.:::.. : ::.::.....:::::.:.::. :::::::.:
NP_001 EVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVN
230 240 250 260 270 280
330 340 350 360 370 380
pF1KE2 KWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYH
:::: ::..::::::::::.:. .:::::::::::.::.::: :::. :: ::::.::::
NP_001 KWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
290 300 310 320 330 340
390 400 410 420 430 440
pF1KE2 NSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELA
:..:::::.:::::::.::::::::::::::::.::::::::::::::::::::::::::
NP_001 NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
350 360 370 380 390 400
450 460 470 480 490 500
pF1KE2 LMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLL
:::::.:::::::::::::::: :::::::::. ::: :::.::::.:::::::::::::
NP_001 LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLL
410 420 430 440 450 460
510 520 530 540 550 560
pF1KE2 ADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEF
:::::::::::::: :::::::::::::::::.::::::::::::: :::::::::: ::
NP_001 ADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEF
470 480 490 500 510 520
570 580 590 600 610 620
pF1KE2 FQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLE
:.::::::: :..::::::::.::::::::::::::.:::::::::::::::::.:::::
NP_001 FRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
530 540 550 560 570 580
630 640 650 660 670 680
pF1KE2 DNREWYQSKIPRSPSDLTN-PE--RDGP-DRFQFELTLEEAEEEDEEEEEEGEETALAKE
:::::::: ::.::: . :: :.: ..::::::::: : : :.. : .. .:
NP_001 DNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDS-GSQV---EE
590 600 610 620 630
690 700 710
pF1KE2 ALELPDTELLSPEAGPDPGDLPLDNQRT
:.. : . . . ..:::.:
NP_001 DTSCSDSKTLCTQDS-ESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
640 650 660 670 680
>>XP_016865058 (OMIM: 600129,606799,614613) PREDICTED: c (699 aa)
initn: 3049 init1: 2084 opt: 3045 Z-score: 2640.4 bits: 499.1 E(85289): 2.5e-140
Smith-Waterman score: 3045; 73.8% identity (87.3% similar) in 638 aa overlap (80-710:41-673)
50 60 70 80 90 100
pF1KE2 PDKSAGCRERDLSPRPELRKSRLSWPVSSCRRFDLENGLSCGRRALDPQSSPGLGRIMQA
::::..:: : :: :::..::: : :.::
XP_016 TLGKVARFRSAYVHGSPYAINMPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQA
20 30 40 50 60 70
110 120 130 140 150 160
pF1KE2 PVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNV
::::::::::::::::.::::.::::::.:::.::.:.::::::::::::::::.:
XP_016 NFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
80 90 100 110 120 130
170 180 190 200 210 220
pF1KE2 AALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSV
:::. : . .:..:. : : :. .:.. :::: :::.::::::::::::::::::
XP_016 AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSV
140 150 160 170 180 190
230 240 250 260 270 280
pF1KE2 GEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ---P
.:::::::::.:::::::::: :::::::::.:: ::::.: :::.:. : .: . :
XP_016 SEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRP
200 210 220 230 240 250
290 300 310 320 330 340
pF1KE2 MSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPL
::.:::.. : ::.::.....:::::.:.::. :::::::.::::: ::..:::::::::
XP_016 MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPL
260 270 280 290 300 310
350 360 370 380 390 400
pF1KE2 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT
:.:. .:::::::::::.::.::: :::. :: ::::.:::::..:::::.:::::::.:
XP_016 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
320 330 340 350 360 370
410 420 430 440 450 460
pF1KE2 PALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGF
:::::::::::::::.:::::::::::::::::::::::::::::::.::::::::::::
XP_016 PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
380 390 400 410 420 430
470 480 490 500 510 520
pF1KE2 KLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVL
:::: :::::::::. ::: :::.::::.::::::::::::::::::::::::::: :::
XP_016 KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
440 450 460 470 480 490
530 540 550 560 570 580
pF1KE2 LLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMC
::::::::::::::.::::::::::::: :::::::::: :::.::::::: :..:::::
XP_016 LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMC
500 510 520 530 540 550
590 600 610 620 630 640
pF1KE2 DKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLT
:::.::::::::::::::.:::::::::::::::::.::::::::::::: ::.:::
XP_016 DKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
560 570 580 590 600 610
650 660 670 680 690 700
pF1KE2 N-PE--RDGP-DRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDP
. :: :.: ..::::::::: : : :.. : .. .: :.. : . .
XP_016 DDPEEGRQGQTEKFQFELTLEEDGESDTEKDS-GSQV---EEDTSCSDSKTLCTQ-DSES
620 630 640 650 660
710
pF1KE2 GDLPLDNQRT
..:::.:
XP_016 TEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
670 680 690
>>XP_005248594 (OMIM: 600129,606799,614613) PREDICTED: c (699 aa)
initn: 3049 init1: 2084 opt: 3045 Z-score: 2640.4 bits: 499.1 E(85289): 2.5e-140
Smith-Waterman score: 3045; 73.8% identity (87.3% similar) in 638 aa overlap (80-710:41-673)
50 60 70 80 90 100
pF1KE2 PDKSAGCRERDLSPRPELRKSRLSWPVSSCRRFDLENGLSCGRRALDPQSSPGLGRIMQA
::::..:: : :: :::..::: : :.::
XP_005 TLGKVARFRSAYVHGSPYAINMPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQA
20 30 40 50 60 70
110 120 130 140 150 160
pF1KE2 PVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNV
::::::::::::::::.::::.::::::.:::.::.:.::::::::::::::::.:
XP_005 NFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
80 90 100 110 120 130
170 180 190 200 210 220
pF1KE2 AALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSV
:::. : . .:..:. : : :. .:.. :::: :::.::::::::::::::::::
XP_005 AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSV
140 150 160 170 180 190
230 240 250 260 270 280
pF1KE2 GEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ---P
.:::::::::.:::::::::: :::::::::.:: ::::.: :::.:. : .: . :
XP_005 SEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRP
200 210 220 230 240 250
290 300 310 320 330 340
pF1KE2 MSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPL
::.:::.. : ::.::.....:::::.:.::. :::::::.::::: ::..:::::::::
XP_005 MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPL
260 270 280 290 300 310
350 360 370 380 390 400
pF1KE2 TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLAT
:.:. .:::::::::::.::.::: :::. :: ::::.:::::..:::::.:::::::.:
XP_005 TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
320 330 340 350 360 370
410 420 430 440 450 460
pF1KE2 PALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGF
:::::::::::::::.:::::::::::::::::::::::::::::::.::::::::::::
XP_005 PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
380 390 400 410 420 430
470 480 490 500 510 520
pF1KE2 KLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVL
:::: :::::::::. ::: :::.::::.::::::::::::::::::::::::::: :::
XP_005 KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
440 450 460 470 480 490
530 540 550 560 570 580
pF1KE2 LLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMC
::::::::::::::.::::::::::::: :::::::::: :::.::::::: :..:::::
XP_005 LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMC
500 510 520 530 540 550
590 600 610 620 630 640
pF1KE2 DKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLT
:::.::::::::::::::.:::::::::::::::::.::::::::::::: ::.:::
XP_005 DKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
560 570 580 590 600 610
650 660 670 680 690 700
pF1KE2 N-PE--RDGP-DRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDP
. :: :.: ..::::::::: : : :.. : .. .: :.. : . .
XP_005 DDPEEGRQGQTEKFQFELTLEEDGESDTEKDS-GSQV---EEDTSCSDSKTLCTQ-DSES
620 630 640 650 660
710
pF1KE2 GDLPLDNQRT
..:::.:
XP_005 TEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
670 680 690
712 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:24:36 2016 done: Sun Nov 6 13:24:38 2016
Total Scan time: 12.840 Total Display time: 0.170
Function used was FASTA [36.3.4 Apr, 2011]