Result of FASTA (omim) for
pFN21AE2046
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2046, 664 aa
1>>>pF1KE2046 664 - 664 aa - 664 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8056+/-0.000378; mu= 17.1077+/- 0.023
mean_var=78.2750+/-16.311, 0's: 0 Z-trim(113.3): 90 B-trim: 904 in 1/51
Lambda= 0.144965
statistics sampled from 22489 (22579) to 22489 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.265), width: 16
Scan time: 7.980
The best scores are: opt bits E(85289)
NP_620130 (OMIM: 613306) alkylated DNA repair prot ( 664) 4487 948.4 0
NP_001287939 (OMIM: 613306) alkylated DNA repair p ( 667) 4487 948.4 0
XP_005271786 (OMIM: 613306) PREDICTED: alkylated D ( 527) 3597 762.3 0
XP_005271785 (OMIM: 613306) PREDICTED: alkylated D ( 527) 3597 762.3 0
XP_016874043 (OMIM: 613306) PREDICTED: alkylated D ( 614) 2875 611.3 3.3e-174
XP_016874042 (OMIM: 613306) PREDICTED: alkylated D ( 617) 2875 611.3 3.4e-174
XP_016874044 (OMIM: 613306) PREDICTED: alkylated D ( 412) 2789 593.2 6.2e-169
XP_016874046 (OMIM: 613306) PREDICTED: alkylated D ( 357) 2292 489.2 1.1e-137
XP_016874045 (OMIM: 613306) PREDICTED: alkylated D ( 362) 1263 274.0 6.6e-73
XP_011542898 (OMIM: 615666) PREDICTED: probable tR ( 539) 547 124.4 1.1e-27
XP_011542899 (OMIM: 615666) PREDICTED: probable tR ( 539) 547 124.4 1.1e-27
XP_005273641 (OMIM: 615666) PREDICTED: probable tR ( 523) 541 123.1 2.6e-27
XP_011542900 (OMIM: 615666) PREDICTED: probable tR ( 474) 535 121.8 5.6e-27
XP_005273642 (OMIM: 615666) PREDICTED: probable tR ( 474) 535 121.8 5.6e-27
XP_011542903 (OMIM: 615666) PREDICTED: probable tR ( 474) 535 121.8 5.6e-27
XP_011542902 (OMIM: 615666) PREDICTED: probable tR ( 474) 535 121.8 5.6e-27
XP_016869196 (OMIM: 615666) PREDICTED: probable tR ( 454) 533 121.4 7.2e-27
XP_005273643 (OMIM: 615666) PREDICTED: probable tR ( 454) 533 121.4 7.2e-27
XP_016869195 (OMIM: 615666) PREDICTED: probable tR ( 454) 533 121.4 7.2e-27
NP_065895 (OMIM: 615666) probable tRNA methyltrans ( 454) 533 121.4 7.2e-27
XP_016869194 (OMIM: 615666) PREDICTED: probable tR ( 454) 533 121.4 7.2e-27
XP_016869198 (OMIM: 615666) PREDICTED: probable tR ( 423) 373 87.9 8.1e-17
XP_016869200 (OMIM: 615666) PREDICTED: probable tR ( 423) 373 87.9 8.1e-17
XP_005273644 (OMIM: 615666) PREDICTED: probable tR ( 423) 373 87.9 8.1e-17
XP_016869197 (OMIM: 615666) PREDICTED: probable tR ( 423) 373 87.9 8.1e-17
XP_016869199 (OMIM: 615666) PREDICTED: probable tR ( 423) 373 87.9 8.1e-17
XP_005273645 (OMIM: 615666) PREDICTED: probable tR ( 423) 373 87.9 8.1e-17
XP_005273648 (OMIM: 615666) PREDICTED: probable tR ( 418) 367 86.7 1.9e-16
XP_016869201 (OMIM: 615666) PREDICTED: probable tR ( 418) 367 86.7 1.9e-16
XP_005273647 (OMIM: 615666) PREDICTED: probable tR ( 418) 367 86.7 1.9e-16
XP_016869203 (OMIM: 615666) PREDICTED: probable tR ( 367) 244 60.9 9.5e-09
XP_016869202 (OMIM: 615666) PREDICTED: probable tR ( 367) 244 60.9 9.5e-09
XP_016869204 (OMIM: 615666) PREDICTED: probable tR ( 328) 182 47.9 6.9e-05
NP_001093147 (OMIM: 615666) probable tRNA methyltr ( 328) 182 47.9 6.9e-05
NP_001284630 (OMIM: 613304) alpha-ketoglutarate-de ( 238) 146 40.3 0.0097
XP_005259414 (OMIM: 613304) PREDICTED: alpha-ketog ( 238) 146 40.3 0.0097
>>NP_620130 (OMIM: 613306) alkylated DNA repair protein (664 aa)
initn: 4487 init1: 4487 opt: 4487 Z-score: 5070.0 bits: 948.4 E(85289): 0
Smith-Waterman score: 4487; 100.0% identity (100.0% similar) in 664 aa overlap (1-664:1-664)
10 20 30 40 50 60
pF1KE2 MDSNHQSNYKLSKTEKKFLRKQIKAKHTLLRHEGIETVSYATQSLVVANGGLGNGVSRNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MDSNHQSNYKLSKTEKKFLRKQIKAKHTLLRHEGIETVSYATQSLVVANGGLGNGVSRNQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LLPVLEKCGLVDALLMPPNKPYSFARYRTTEESKRAYVTLNGKEVVDDLGQKITLYLNFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LLPVLEKCGLVDALLMPPNKPYSFARYRTTEESKRAYVTLNGKEVVDDLGQKITLYLNFV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVKHFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 EKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVKHFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTINQYEPGQGIPAHID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 YEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTINQYEPGQGIPAHID
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 THSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESRYLWTHGITCRKFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 THSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESRYLWTHGITCRKFD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRKETPPSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRKETPPSF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGNGKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGNGKY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDACISIAVIHHFATAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDACISIAVIHHFATAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 RRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGKKEEMNSDTSVQRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 RRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGKKEEMNSDTSVQRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSFYSQDVLVPWHLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSFYSQDVLVPWHLKG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 NPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRTVSDVRILQSYYDQGNWCVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 NPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRTVSDVRILQSYYDQGNWCVI
610 620 630 640 650 660
pF1KE2 LQKA
::::
NP_620 LQKA
>>NP_001287939 (OMIM: 613306) alkylated DNA repair prote (667 aa)
initn: 4487 init1: 4487 opt: 4487 Z-score: 5069.9 bits: 948.4 E(85289): 0
Smith-Waterman score: 4487; 100.0% identity (100.0% similar) in 664 aa overlap (1-664:4-667)
10 20 30 40 50
pF1KE2 MDSNHQSNYKLSKTEKKFLRKQIKAKHTLLRHEGIETVSYATQSLVVANGGLGNGVS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFAMDSNHQSNYKLSKTEKKFLRKQIKAKHTLLRHEGIETVSYATQSLVVANGGLGNGVS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 RNQLLPVLEKCGLVDALLMPPNKPYSFARYRTTEESKRAYVTLNGKEVVDDLGQKITLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNQLLPVLEKCGLVDALLMPPNKPYSFARYRTTEESKRAYVTLNGKEVVDDLGQKITLYL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 NFVEKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFVEKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 HFGYEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTINQYEPGQGIPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HFGYEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTINQYEPGQGIPA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 HIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESRYLWTHGITCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESRYLWTHGITCR
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 KFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRKETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRKETP
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 PSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGN
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 GKYLGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDACISIAVIHHFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKYLGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDACISIAVIHHFA
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 TAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGKKEEMNSDTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGKKEEMNSDTSV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 QRSLVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSFYSQDVLVPWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRSLVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSFYSQDVLVPWH
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 LKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRTVSDVRILQSYYDQGNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRTVSDVRILQSYYDQGNW
610 620 630 640 650 660
660
pF1KE2 CVILQKA
:::::::
NP_001 CVILQKA
>>XP_005271786 (OMIM: 613306) PREDICTED: alkylated DNA r (527 aa)
initn: 3597 init1: 3597 opt: 3597 Z-score: 4065.5 bits: 762.3 E(85289): 0
Smith-Waterman score: 3597; 100.0% identity (100.0% similar) in 527 aa overlap (138-664:1-527)
110 120 130 140 150 160
pF1KE2 DLGQKITLYLNFVEKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNS
::::::::::::::::::::::::::::::
XP_005 MVVEEIISSEEEKMLLESVDWTEDTDNQNS
10 20 30
170 180 190 200 210 220
pF1KE2 QKSLKHRRVKHFGYEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKSLKHRRVKHFGYEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTIN
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE2 QYEPGQGIPAHIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QYEPGQGIPAHIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESR
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE2 YLWTHGITCRKFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLWTHGITCRKFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPL
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE2 VCDSQRKETPPSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCDSQRKETPPSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSG
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE2 SIVADIGCGNGKYLGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIVADIGCGNGKYLGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDAC
280 290 300 310 320 330
470 480 490 500 510 520
pF1KE2 ISIAVIHHFATAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISIAVIHHFATAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGK
340 350 360 370 380 390
530 540 550 560 570 580
pF1KE2 KEEMNSDTSVQRSLVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEEMNSDTSVQRSLVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSF
400 410 420 430 440 450
590 600 610 620 630 640
pF1KE2 YSQDVLVPWHLKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRTVSDVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSQDVLVPWHLKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRTVSDVRI
460 470 480 490 500 510
650 660
pF1KE2 LQSYYDQGNWCVILQKA
:::::::::::::::::
XP_005 LQSYYDQGNWCVILQKA
520
>>XP_005271785 (OMIM: 613306) PREDICTED: alkylated DNA r (527 aa)
initn: 3597 init1: 3597 opt: 3597 Z-score: 4065.5 bits: 762.3 E(85289): 0
Smith-Waterman score: 3597; 100.0% identity (100.0% similar) in 527 aa overlap (138-664:1-527)
110 120 130 140 150 160
pF1KE2 DLGQKITLYLNFVEKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNS
::::::::::::::::::::::::::::::
XP_005 MVVEEIISSEEEKMLLESVDWTEDTDNQNS
10 20 30
170 180 190 200 210 220
pF1KE2 QKSLKHRRVKHFGYEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKSLKHRRVKHFGYEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTIN
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE2 QYEPGQGIPAHIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QYEPGQGIPAHIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESR
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE2 YLWTHGITCRKFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLWTHGITCRKFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPL
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE2 VCDSQRKETPPSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCDSQRKETPPSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSG
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE2 SIVADIGCGNGKYLGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIVADIGCGNGKYLGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDAC
280 290 300 310 320 330
470 480 490 500 510 520
pF1KE2 ISIAVIHHFATAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISIAVIHHFATAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGK
340 350 360 370 380 390
530 540 550 560 570 580
pF1KE2 KEEMNSDTSVQRSLVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEEMNSDTSVQRSLVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSF
400 410 420 430 440 450
590 600 610 620 630 640
pF1KE2 YSQDVLVPWHLKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRTVSDVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSQDVLVPWHLKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRTVSDVRI
460 470 480 490 500 510
650 660
pF1KE2 LQSYYDQGNWCVILQKA
:::::::::::::::::
XP_005 LQSYYDQGNWCVILQKA
520
>>XP_016874043 (OMIM: 613306) PREDICTED: alkylated DNA r (614 aa)
initn: 4124 init1: 2875 opt: 2875 Z-score: 3248.5 bits: 611.3 E(85289): 3.3e-174
Smith-Waterman score: 4028; 92.5% identity (92.5% similar) in 664 aa overlap (1-664:1-614)
10 20 30 40 50 60
pF1KE2 MDSNHQSNYKLSKTEKKFLRKQIKAKHTLLRHEGIETVSYATQSLVVANGGLGNGVSRNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDSNHQSNYKLSKTEKKFLRKQIKAKHTLLRHEGIETVSYATQSLVVANGGLGNGVSRNQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LLPVLEKCGLVDALLMPPNKPYSFARYRTTEESKRAYVTLNGKEVVDDLGQKITLYLNFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLPVLEKCGLVDALLMPPNKPYSFARYRTTEESKRAYVTLNGKEVVDDLGQKITLYLNFV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVKHFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVKHFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTINQYEPGQGIPAHID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTINQYEPGQGIPAHID
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 THSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESRYLWTHGITCRKFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESRYLWTHGITCRKFD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRKETPPSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRKETPPSF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGNGKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGNGKY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDACISIAVIHHFATAE
::::::::: :
XP_016 LGINKELYM--------------------------------------------------E
430
490 500 510 520 530 540
pF1KE2 RRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGKKEEMNSDTSVQRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGKKEEMNSDTSVQRS
440 450 460 470 480 490
550 560 570 580 590 600
pF1KE2 LVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSFYSQDVLVPWHLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSFYSQDVLVPWHLKG
500 510 520 530 540 550
610 620 630 640 650 660
pF1KE2 NPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRTVSDVRILQSYYDQGNWCVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRTVSDVRILQSYYDQGNWCVI
560 570 580 590 600 610
pF1KE2 LQKA
::::
XP_016 LQKA
>>XP_016874042 (OMIM: 613306) PREDICTED: alkylated DNA r (617 aa)
initn: 4124 init1: 2875 opt: 2875 Z-score: 3248.4 bits: 611.3 E(85289): 3.4e-174
Smith-Waterman score: 4028; 92.5% identity (92.5% similar) in 664 aa overlap (1-664:4-617)
10 20 30 40 50
pF1KE2 MDSNHQSNYKLSKTEKKFLRKQIKAKHTLLRHEGIETVSYATQSLVVANGGLGNGVS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFAMDSNHQSNYKLSKTEKKFLRKQIKAKHTLLRHEGIETVSYATQSLVVANGGLGNGVS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 RNQLLPVLEKCGLVDALLMPPNKPYSFARYRTTEESKRAYVTLNGKEVVDDLGQKITLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNQLLPVLEKCGLVDALLMPPNKPYSFARYRTTEESKRAYVTLNGKEVVDDLGQKITLYL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 NFVEKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFVEKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 HFGYEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTINQYEPGQGIPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFGYEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTINQYEPGQGIPA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 HIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESRYLWTHGITCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESRYLWTHGITCR
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 KFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRKETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRKETP
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 PSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGN
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 GKYLGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDACISIAVIHHFA
::::::::::::
XP_016 GKYLGINKELYM------------------------------------------------
430
480 490 500 510 520 530
pF1KE2 TAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGKKEEMNSDTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --ERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGKKEEMNSDTSV
440 450 460 470 480 490
540 550 560 570 580 590
pF1KE2 QRSLVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSFYSQDVLVPWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRSLVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSFYSQDVLVPWH
500 510 520 530 540 550
600 610 620 630 640 650
pF1KE2 LKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRTVSDVRILQSYYDQGNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRTVSDVRILQSYYDQGNW
560 570 580 590 600 610
660
pF1KE2 CVILQKA
:::::::
XP_016 CVILQKA
>>XP_016874044 (OMIM: 613306) PREDICTED: alkylated DNA r (412 aa)
initn: 2784 init1: 2784 opt: 2789 Z-score: 3153.9 bits: 593.2 E(85289): 6.2e-169
Smith-Waterman score: 2789; 99.0% identity (99.8% similar) in 413 aa overlap (252-664:1-412)
230 240 250 260 270 280
pF1KE2 DQMTINQYEPGQGIPAHIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLV
..:: .::::::::::::::::::::::::
XP_016 MNLG-KIVMDFKHPDGIAVPVMLPRRSLLV
10 20
290 300 310 320 330 340
pF1KE2 MTGESRYLWTHGITCRKFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTGESRYLWTHGITCRKFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPC
30 40 50 60 70 80
350 360 370 380 390 400
pF1KE2 NCSYPLVCDSQRKETPPSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCSYPLVCDSQRKETPPSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFL
90 100 110 120 130 140
410 420 430 440 450 460
pF1KE2 KALPSGSIVADIGCGNGKYLGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALPSGSIVADIGCGNGKYLGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRS
150 160 170 180 190 200
470 480 490 500 510 520
pF1KE2 GSCDACISIAVIHHFATAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSCDACISIAVIHHFATAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGN
210 220 230 240 250 260
530 540 550 560 570 580
pF1KE2 RNSQGKKEEMNSDTSVQRSLVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNSQGKKEEMNSDTSVQRSLVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVH
270 280 290 300 310 320
590 600 610 620 630 640
pF1KE2 VNRTSFYSQDVLVPWHLKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNRTSFYSQDVLVPWHLKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRT
330 340 350 360 370 380
650 660
pF1KE2 VSDVRILQSYYDQGNWCVILQKA
:::::::::::::::::::::::
XP_016 VSDVRILQSYYDQGNWCVILQKA
390 400 410
>>XP_016874046 (OMIM: 613306) PREDICTED: alkylated DNA r (357 aa)
initn: 2286 init1: 2286 opt: 2292 Z-score: 2593.1 bits: 489.2 E(85289): 1.1e-137
Smith-Waterman score: 2292; 98.9% identity (99.1% similar) in 349 aa overlap (1-349:4-352)
10 20 30 40 50
pF1KE2 MDSNHQSNYKLSKTEKKFLRKQIKAKHTLLRHEGIETVSYATQSLVVANGGLGNGVS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFAMDSNHQSNYKLSKTEKKFLRKQIKAKHTLLRHEGIETVSYATQSLVVANGGLGNGVS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 RNQLLPVLEKCGLVDALLMPPNKPYSFARYRTTEESKRAYVTLNGKEVVDDLGQKITLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNQLLPVLEKCGLVDALLMPPNKPYSFARYRTTEESKRAYVTLNGKEVVDDLGQKITLYL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 NFVEKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFVEKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 HFGYEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTINQYEPGQGIPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFGYEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTINQYEPGQGIPA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 HIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESRYLWTHGITCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESRYLWTHGITCR
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 KFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRKETP
::::::::::::::::::::::::::::::::::::::::::::::: . :
XP_016 KFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSTLIPCLGCCE
310 320 330 340 350
360 370 380 390 400 410
pF1KE2 PSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGN
>>XP_016874045 (OMIM: 613306) PREDICTED: alkylated DNA r (362 aa)
initn: 2421 init1: 1263 opt: 1263 Z-score: 1429.9 bits: 274.0 E(85289): 6.6e-73
Smith-Waterman score: 2330; 86.9% identity (87.7% similar) in 413 aa overlap (252-664:1-362)
230 240 250 260 270 280
pF1KE2 DQMTINQYEPGQGIPAHIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLV
..:: .::::::::::::::::::::::::
XP_016 MNLG-KIVMDFKHPDGIAVPVMLPRRSLLV
10 20
290 300 310 320 330 340
pF1KE2 MTGESRYLWTHGITCRKFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTGESRYLWTHGITCRKFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPC
30 40 50 60 70 80
350 360 370 380 390 400
pF1KE2 NCSYPLVCDSQRKETPPSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCSYPLVCDSQRKETPPSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFL
90 100 110 120 130 140
410 420 430 440 450 460
pF1KE2 KALPSGSIVADIGCGNGKYLGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRS
::::::::::::::::::::::::::::
XP_016 KALPSGSIVADIGCGNGKYLGINKELYM--------------------------------
150 160 170
470 480 490 500 510 520
pF1KE2 GSCDACISIAVIHHFATAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGN
::::::::::::::::::::::::::::::::::::::::::
XP_016 ------------------ERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGN
180 190 200 210
530 540 550 560 570 580
pF1KE2 RNSQGKKEEMNSDTSVQRSLVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNSQGKKEEMNSDTSVQRSLVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVH
220 230 240 250 260 270
590 600 610 620 630 640
pF1KE2 VNRTSFYSQDVLVPWHLKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNRTSFYSQDVLVPWHLKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEGACRT
280 290 300 310 320 330
650 660
pF1KE2 VSDVRILQSYYDQGNWCVILQKA
:::::::::::::::::::::::
XP_016 VSDVRILQSYYDQGNWCVILQKA
340 350 360
>>XP_011542898 (OMIM: 615666) PREDICTED: probable tRNA m (539 aa)
initn: 724 init1: 524 opt: 547 Z-score: 618.0 bits: 124.4 E(85289): 1.1e-27
Smith-Waterman score: 547; 47.0% identity (75.0% similar) in 168 aa overlap (349-513:74-239)
320 330 340 350 360 370
pF1KE2 DLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRKETPPSFPESDKEASRLEQEYVHQV
: . : .. : : :.::..::...::.:
XP_011 GAERSFCCALDPLPRRPPAGRRGRDRSSSACPGARARVWP--PGMDHEAAQLEKQHVHNV
50 60 70 80 90 100
380 390 400 410 420 430
pF1KE2 YEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGNGKYLGINKELYMIGCDRSQNL
:: : .::. . ::.. .::. ::..::::::.:::: .:.... .::: :
XP_011 YESTAPYFSDLQSKAWPRVRQFLQEQKPGSLIADIGCGTGKYLKVNSQVHTVGCDYCGPL
110 120 130 140 150 160
440 450 460 470 480 490
pF1KE2 VDICRERQFQAFVCDALAVPVRSGSCDACISIAVIHHFATAERRVAALQEIVRLLRPGGK
:.: :.: .:.::: : .: :. . :: :::.:::::.: .::. :..:..:.: :::.
XP_011 VEIARNRGCEAMVCDNLNLPFRDEGFDAIISIGVIHHFSTKQRRIRAIKEMARVLVPGGQ
170 180 190 200 210 220
500 510 520 530 540 550
pF1KE2 ALIYVWAMEQE---YNKQKSKYLRGNRNSQGKKEEMNSDTSVQRSLVEQMRDMGSRDSAS
.::::::::. ..::
XP_011 LMIYVWAMEQKNRHFEKQDVLVPWNRALCSQLFSESSQSGRKRQCGYPERGHPYHPPCSE
230 240 250 260 270 280
>--
initn: 234 init1: 97 opt: 182 Z-score: 205.5 bits: 48.0 E(85289): 0.0001
Smith-Waterman score: 182; 50.0% identity (67.2% similar) in 64 aa overlap (601-663:473-534)
580 590 600 610 620 630
pF1KE2 RQVSNSKLPVHVNRTSFYSQDVLVPWHLKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVF
::: :: : . : .: ::::::
XP_011 NCVDAGNIEDDNPSASKILRRISAVDSTDFNPDDTMSVE--DPQTDVLDSTAFMRYYHVF
450 460 470 480 490 500
640 650 660
pF1KE2 REGELEGACR-TVSDVRILQSYYDQGNWCVILQKA
::::: . . .::..:::.: :.::::.: .:
XP_011 REGELCSLLKENVSELRILSSGNDHGNWCIIAEKKRGCD
510 520 530
664 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:00:05 2016 done: Sun Nov 6 15:00:06 2016
Total Scan time: 7.980 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]