Result of FASTA (omim) for
pFN21AE2031
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2031, 621 aa
1>>>pF1KE2031 621 - 621 aa - 621 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2066+/-0.000392; mu= 20.0469+/- 0.025
mean_var=73.6613+/-14.445, 0's: 0 Z-trim(112.9): 19 B-trim: 0 in 0/54
Lambda= 0.149436
statistics sampled from 21930 (21942) to 21930 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.257), width: 16
Scan time: 11.330
The best scores are: opt bits E(85289)
XP_005274491 (OMIM: 300162,400011) PREDICTED: N-ac ( 621) 4113 896.5 0
XP_005274840 (OMIM: 300162,400011) PREDICTED: N-ac ( 621) 4113 896.5 0
NP_004183 (OMIM: 300162,400011) N-acetylserotonin ( 621) 4113 896.5 0
NP_001166944 (OMIM: 300162,400011) N-acetylseroton ( 563) 3740 816.1 0
XP_011544487 (OMIM: 300162,400011) PREDICTED: N-ac ( 538) 3538 772.5 0
XP_011543940 (OMIM: 300162,400011) PREDICTED: N-ac ( 538) 3538 772.5 0
NP_001166945 (OMIM: 300162,400011) N-acetylseroton ( 605) 3538 772.6 0
XP_016885573 (OMIM: 300162,400011) PREDICTED: N-ac ( 512) 3421 747.3 3e-215
XP_016885408 (OMIM: 300162,400011) PREDICTED: N-ac ( 512) 3421 747.3 3e-215
NP_004034 (OMIM: 300015,402500) acetylserotonin O- ( 373) 510 119.6 2e-26
NP_001164509 (OMIM: 300015,402500) acetylserotonin ( 373) 510 119.6 2e-26
NP_001164510 (OMIM: 300015,402500) acetylserotonin ( 298) 408 97.5 6.9e-20
>>XP_005274491 (OMIM: 300162,400011) PREDICTED: N-acetyl (621 aa)
initn: 4113 init1: 4113 opt: 4113 Z-score: 4790.5 bits: 896.5 E(85289): 0
Smith-Waterman score: 4113; 100.0% identity (100.0% similar) in 621 aa overlap (1-621:1-621)
10 20 30 40 50 60
pF1KE2 MVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 ANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 FDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 RVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFH
550 560 570 580 590 600
610 620
pF1KE2 QVQVVHLGGVLDAILATKVAP
:::::::::::::::::::::
XP_005 QVQVVHLGGVLDAILATKVAP
610 620
>>XP_005274840 (OMIM: 300162,400011) PREDICTED: N-acetyl (621 aa)
initn: 4113 init1: 4113 opt: 4113 Z-score: 4790.5 bits: 896.5 E(85289): 0
Smith-Waterman score: 4113; 100.0% identity (100.0% similar) in 621 aa overlap (1-621:1-621)
10 20 30 40 50 60
pF1KE2 MVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 ANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 FDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 RVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFH
550 560 570 580 590 600
610 620
pF1KE2 QVQVVHLGGVLDAILATKVAP
:::::::::::::::::::::
XP_005 QVQVVHLGGVLDAILATKVAP
610 620
>>NP_004183 (OMIM: 300162,400011) N-acetylserotonin O-me (621 aa)
initn: 4113 init1: 4113 opt: 4113 Z-score: 4790.5 bits: 896.5 E(85289): 0
Smith-Waterman score: 4113; 100.0% identity (100.0% similar) in 621 aa overlap (1-621:1-621)
10 20 30 40 50 60
pF1KE2 MVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 ANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 FDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 RVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFH
550 560 570 580 590 600
610 620
pF1KE2 QVQVVHLGGVLDAILATKVAP
:::::::::::::::::::::
NP_004 QVQVVHLGGVLDAILATKVAP
610 620
>>NP_001166944 (OMIM: 300162,400011) N-acetylserotonin O (563 aa)
initn: 3740 init1: 3740 opt: 3740 Z-score: 4356.5 bits: 816.1 E(85289): 0
Smith-Waterman score: 3740; 100.0% identity (100.0% similar) in 563 aa overlap (59-621:1-563)
30 40 50 60 70 80
pF1KE2 SNAGLRFEVVPSKFKEKLDKASFATPYGYAMETAKQKALEVANRLYQKDLRAPDVVIGAD
::::::::::::::::::::::::::::::
NP_001 METAKQKALEVANRLYQKDLRAPDVVIGAD
10 20 30
90 100 110 120 130 140
pF1KE2 TIVTVGGLILEKPVDKQDAYRMLSRLSGREHSVFTGVAIVHCSSKDHQLDTRVSEFYEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIVTVGGLILEKPVDKQDAYRMLSRLSGREHSVFTGVAIVHCSSKDHQLDTRVSEFYEET
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 KVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGFPLNHFCKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGFPLNHFCKQL
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE2 VKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQA
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE2 TAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQKAADIASKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQKAADIASKV
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE2 DASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMHNNDLTWNLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMHNNDLTWNLF
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE2 TYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLTACQVATAFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLTACQVATAFN
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE2 LSRFSSACDVGGCTGALARELAREYPRMQVTVFDLPDIIELAAHFQPPGPQAVQIHFAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSRFSSACDVGGCTGALARELAREYPRMQVTVFDLPDIIELAAHFQPPGPQAVQIHFAAG
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE2 DFFRDPLPSAELYVLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLLDEEKRVAQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFFRDPLPSAELYVLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLLDEEKRVAQR
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE2 ALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP
520 530 540 550 560
>>XP_011544487 (OMIM: 300162,400011) PREDICTED: N-acetyl (538 aa)
initn: 3538 init1: 3538 opt: 3538 Z-score: 4121.4 bits: 772.5 E(85289): 0
Smith-Waterman score: 3538; 100.0% identity (100.0% similar) in 530 aa overlap (92-621:9-538)
70 80 90 100 110 120
pF1KE2 AKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHSV
::::::::::::::::::::::::::::::
XP_011 MTTPRPQQTVGGLILEKPVDKQDAYRMLSRLSGREHSV
10 20 30
130 140 150 160 170 180
pF1KE2 FTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQAL
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE2 GGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDV
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE2 EGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGL
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE2 LTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETA
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE2 NVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQS
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE2 PETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVF
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE2 DLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSR
400 410 420 430 440 450
550 560 570 580 590 600
pF1KE2 VAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQ
460 470 480 490 500 510
610 620
pF1KE2 VQVVHLGGVLDAILATKVAP
::::::::::::::::::::
XP_011 VQVVHLGGVLDAILATKVAP
520 530
>>XP_011543940 (OMIM: 300162,400011) PREDICTED: N-acetyl (538 aa)
initn: 3538 init1: 3538 opt: 3538 Z-score: 4121.4 bits: 772.5 E(85289): 0
Smith-Waterman score: 3538; 100.0% identity (100.0% similar) in 530 aa overlap (92-621:9-538)
70 80 90 100 110 120
pF1KE2 AKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHSV
::::::::::::::::::::::::::::::
XP_011 MTTPRPQQTVGGLILEKPVDKQDAYRMLSRLSGREHSV
10 20 30
130 140 150 160 170 180
pF1KE2 FTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQAL
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE2 GGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDV
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE2 EGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGL
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE2 LTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETA
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE2 NVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQS
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE2 PETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVF
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE2 DLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSR
400 410 420 430 440 450
550 560 570 580 590 600
pF1KE2 VAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQ
460 470 480 490 500 510
610 620
pF1KE2 VQVVHLGGVLDAILATKVAP
::::::::::::::::::::
XP_011 VQVVHLGGVLDAILATKVAP
520 530
>>NP_001166945 (OMIM: 300162,400011) N-acetylserotonin O (605 aa)
initn: 3999 init1: 3538 opt: 3538 Z-score: 4120.7 bits: 772.6 E(85289): 0
Smith-Waterman score: 3971; 97.4% identity (97.4% similar) in 621 aa overlap (1-621:1-605)
10 20 30 40 50 60
pF1KE2 MVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHS
::::::::::::::: :::::::::::::::::::::::::::::
NP_001 TAKQKALEVANRLYQ----------------TVGGLILEKPVDKQDAYRMLSRLSGREHS
70 80 90 100
130 140 150 160 170 180
pF1KE2 VFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 LGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSD
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE2 VEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKG
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE2 LLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTET
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE2 ANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQ
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE2 SPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTV
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE2 FDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLS
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE2 RVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFH
530 540 550 560 570 580
610 620
pF1KE2 QVQVVHLGGVLDAILATKVAP
:::::::::::::::::::::
NP_001 QVQVVHLGGVLDAILATKVAP
590 600
>>XP_016885573 (OMIM: 300162,400011) PREDICTED: N-acetyl (512 aa)
initn: 3421 init1: 3421 opt: 3421 Z-score: 3985.3 bits: 747.3 E(85289): 3e-215
Smith-Waterman score: 3421; 100.0% identity (100.0% similar) in 512 aa overlap (110-621:1-512)
80 90 100 110 120 130
pF1KE2 APDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHSVFTGVAIVHCSSKDHQLDT
::::::::::::::::::::::::::::::
XP_016 MLSRLSGREHSVFTGVAIVHCSSKDHQLDT
10 20 30
140 150 160 170 180 190
pF1KE2 RVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGF
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 PLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEK
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE2 AEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQ
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE2 KAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMH
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE2 NNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLT
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE2 ACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVFDLPDIIELAAHFQPPGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVFDLPDIIELAAHFQPPGPQ
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE2 AVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLL
400 410 420 430 440 450
560 570 580 590 600 610
pF1KE2 DEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKV
460 470 480 490 500 510
620
pF1KE2 AP
::
XP_016 AP
>>XP_016885408 (OMIM: 300162,400011) PREDICTED: N-acetyl (512 aa)
initn: 3421 init1: 3421 opt: 3421 Z-score: 3985.3 bits: 747.3 E(85289): 3e-215
Smith-Waterman score: 3421; 100.0% identity (100.0% similar) in 512 aa overlap (110-621:1-512)
80 90 100 110 120 130
pF1KE2 APDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHSVFTGVAIVHCSSKDHQLDT
::::::::::::::::::::::::::::::
XP_016 MLSRLSGREHSVFTGVAIVHCSSKDHQLDT
10 20 30
140 150 160 170 180 190
pF1KE2 RVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGF
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 PLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEK
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE2 AEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQ
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE2 KAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMH
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE2 NNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLT
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE2 ACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVFDLPDIIELAAHFQPPGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVFDLPDIIELAAHFQPPGPQ
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE2 AVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLL
400 410 420 430 440 450
560 570 580 590 600 610
pF1KE2 DEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKV
460 470 480 490 500 510
620
pF1KE2 AP
::
XP_016 AP
>>NP_004034 (OMIM: 300015,402500) acetylserotonin O-meth (373 aa)
initn: 808 init1: 425 opt: 510 Z-score: 595.5 bits: 119.6 E(85289): 2e-26
Smith-Waterman score: 794; 40.3% identity (63.8% similar) in 367 aa overlap (287-618:10-373)
260 270 280 290 300 310
pF1KE2 DEKAEAGEAGQATAEAECHRTRETLPPFPTRLL-ELIEGFMLSKGLLTACKLKVFDLLKD
::: . .:::.:. :..::.: ::::: .
NP_004 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAE
10 20 30
320 330 340 350 360 370
pF1KE2 E-APQKAADIASKVDASACGMERLLDICAAMGLLEKTEQG----YSNTETANVYLASDGE
.: .: .:. : ::: : : :::::... ::. .: : ::: .. ::.. .
NP_004 APGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSP
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE2 YSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMR
: ... . . .. . .: :.::: ::. ...: ::.:: : :.: ::.::.
NP_004 TSQCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFGVPAEELFT-AIYRSEGERLQFMQ
100 110 120 130 140 150
440 450 460
pF1KE2 AMHGMTKLTACQVATAFNLSRFSSACDVGGC----------------------------T
:.. . .... .: :::.:: : ::.:: .
NP_004 ALQEVWSVNGRSVLTAFDLSVFPLMCDLGGTWIKLETIILSKLSQGQKTKHRVFSLIGGA
160 170 180 190 200 210
470 480 490 500 510 520
pF1KE2 GALARELAREYPRMQVTVFDLPDIIELAA-HFQPPGPQAVQIHFAAGDFFRDPLPSAELY
::::.: :: ..::::.:... : ::. . :: : ::::.:::: :.::
NP_004 GALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQ--EEEQIDFQEGDFFKDPLPEADLY
220 230 240 250 260 270
530 540 550 560 570 580
pF1KE2 VLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTE
.: :.:::: : : .:: :. ..::::.:.:..:.::::..: . . :::::::::
NP_004 ILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTE
280 290 300 310 320 330
590 600 610 620
pF1KE2 GKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP
:.::. .:. :: ::.. : . :.. ::::: :
NP_004 GQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK
340 350 360 370
621 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 10:51:42 2016 done: Sun Nov 6 10:51:44 2016
Total Scan time: 11.330 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]