Result of FASTA (omim) for
pFN21AE2023
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2023, 599 aa
1>>>pF1KE2023 599 - 599 aa - 599 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8450+/-0.000349; mu= -0.0651+/- 0.022
mean_var=285.5664+/-61.003, 0's: 0 Z-trim(123.7): 19 B-trim: 3600 in 2/60
Lambda= 0.075896
statistics sampled from 44026 (44046) to 44026 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.812), E-opt: 0.2 (0.516), width: 16
Scan time: 13.730
The best scores are: opt bits E(85289)
NP_001310479 (OMIM: 610562) endoribonuclease ZC3H1 ( 599) 4173 470.3 8.3e-132
NP_079355 (OMIM: 610562) endoribonuclease ZC3H12A ( 599) 4173 470.3 8.3e-132
NP_001310480 (OMIM: 610562) endoribonuclease ZC3H1 ( 325) 2314 266.5 9.9e-71
XP_011540500 (OMIM: 610562) PREDICTED: bifunctiona ( 394) 1852 216.0 1.9e-55
XP_011541357 (OMIM: 615001) PREDICTED: probable ri ( 852) 1395 166.2 4e-40
NP_203748 (OMIM: 615001) probable ribonuclease ZC3 ( 883) 1395 166.2 4.1e-40
XP_005271772 (OMIM: 615001) PREDICTED: probable ri ( 884) 1395 166.2 4.1e-40
XP_016873966 (OMIM: 615001) PREDICTED: probable ri ( 884) 1395 166.2 4.1e-40
XP_016884969 (OMIM: 300889) PREDICTED: probable ri ( 836) 1384 165.0 9e-40
XP_016884968 (OMIM: 300889) PREDICTED: probable ri ( 836) 1384 165.0 9e-40
XP_016884972 (OMIM: 300889) PREDICTED: probable ri ( 836) 1384 165.0 9e-40
XP_016884973 (OMIM: 300889) PREDICTED: probable ri ( 836) 1384 165.0 9e-40
XP_016884971 (OMIM: 300889) PREDICTED: probable ri ( 836) 1384 165.0 9e-40
XP_011529241 (OMIM: 300889) PREDICTED: probable ri ( 836) 1384 165.0 9e-40
XP_016884970 (OMIM: 300889) PREDICTED: probable ri ( 836) 1384 165.0 9e-40
NP_001010888 (OMIM: 300889) probable ribonuclease ( 836) 1384 165.0 9e-40
XP_016884967 (OMIM: 300889) PREDICTED: probable ri ( 836) 1384 165.0 9e-40
NP_997243 (OMIM: 611106) probable ribonuclease ZC3 ( 527) 1263 151.6 6.2e-36
>>NP_001310479 (OMIM: 610562) endoribonuclease ZC3H12A i (599 aa)
initn: 4173 init1: 4173 opt: 4173 Z-score: 2487.4 bits: 470.3 E(85289): 8.3e-132
Smith-Waterman score: 4173; 100.0% identity (100.0% similar) in 599 aa overlap (1-599:1-599)
10 20 30 40 50 60
pF1KE2 MSGPCGEKPVLEASPTMSLWEFEDSHSRQGTPRPGQELAAEEASALELQMKVDFFRKLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGPCGEKPVLEASPTMSLWEFEDSHSRQGTPRPGQELAAEEASALELQMKVDFFRKLGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SSTEIHSVLQKLGVQADTNTVLGELVKHGTATERERQTSPDPCPQLPLVPRGGGTPKAPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSTEIHSVLQKLGVQADTNTVLGELVKHGTATERERQTSPDPCPQLPLVPRGGGTPKAPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LEPPLPEEEKEGSDLRPVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEPPLPEEEKEGSDLRPVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SWRKEQPRPDVPITDQHILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAYESDGIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWRKEQPRPDVPITDQHILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAYESDGIV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VSNDTYRDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLTLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSNDTYRDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLTLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 HRKQPCPYGRKCTYGIKCRFFHPERPSCPQRSVADELRANALLSPPRAPSKDKNGRRPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRKQPCPYGRKCTYGIKCRFFHPERPSCPQRSVADELRANALLSPPRAPSKDKNGRRPSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 SSQSSSLLTESEQCSLDGKKLGAQASPGSRQEGLTQTYAPSGRSLAPSGGSGSSFGPTDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSQSSSLLTESEQCSLDGKKLGAQASPGSRQEGLTQTYAPSGRSLAPSGGSGSSFGPTDW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LPQTLDSLPYVSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPQTLDSLPYVSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 TAAFSAFGRAMGAGHFSVPADYPPAPPAFPPREYWSEPYPLPPPTSVLQEPPVQSPGAGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAAFSAFGRAMGAGHFSVPADYPPAPPAFPPREYWSEPYPLPPPTSVLQEPPVQSPGAGR
490 500 510 520 530 540
550 560 570 580 590
pF1KE2 SPWGRAGSLAKEQASVYTKLCGVFPPHLVEAVMGRFPQLLDPQQLAAEILSYKSQHPSE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPWGRAGSLAKEQASVYTKLCGVFPPHLVEAVMGRFPQLLDPQQLAAEILSYKSQHPSE
550 560 570 580 590
>>NP_079355 (OMIM: 610562) endoribonuclease ZC3H12A isof (599 aa)
initn: 4173 init1: 4173 opt: 4173 Z-score: 2487.4 bits: 470.3 E(85289): 8.3e-132
Smith-Waterman score: 4173; 100.0% identity (100.0% similar) in 599 aa overlap (1-599:1-599)
10 20 30 40 50 60
pF1KE2 MSGPCGEKPVLEASPTMSLWEFEDSHSRQGTPRPGQELAAEEASALELQMKVDFFRKLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MSGPCGEKPVLEASPTMSLWEFEDSHSRQGTPRPGQELAAEEASALELQMKVDFFRKLGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SSTEIHSVLQKLGVQADTNTVLGELVKHGTATERERQTSPDPCPQLPLVPRGGGTPKAPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SSTEIHSVLQKLGVQADTNTVLGELVKHGTATERERQTSPDPCPQLPLVPRGGGTPKAPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LEPPLPEEEKEGSDLRPVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LEPPLPEEEKEGSDLRPVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SWRKEQPRPDVPITDQHILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAYESDGIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SWRKEQPRPDVPITDQHILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAYESDGIV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VSNDTYRDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLTLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VSNDTYRDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLTLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 HRKQPCPYGRKCTYGIKCRFFHPERPSCPQRSVADELRANALLSPPRAPSKDKNGRRPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 HRKQPCPYGRKCTYGIKCRFFHPERPSCPQRSVADELRANALLSPPRAPSKDKNGRRPSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 SSQSSSLLTESEQCSLDGKKLGAQASPGSRQEGLTQTYAPSGRSLAPSGGSGSSFGPTDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SSQSSSLLTESEQCSLDGKKLGAQASPGSRQEGLTQTYAPSGRSLAPSGGSGSSFGPTDW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LPQTLDSLPYVSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LPQTLDSLPYVSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 TAAFSAFGRAMGAGHFSVPADYPPAPPAFPPREYWSEPYPLPPPTSVLQEPPVQSPGAGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 TAAFSAFGRAMGAGHFSVPADYPPAPPAFPPREYWSEPYPLPPPTSVLQEPPVQSPGAGR
490 500 510 520 530 540
550 560 570 580 590
pF1KE2 SPWGRAGSLAKEQASVYTKLCGVFPPHLVEAVMGRFPQLLDPQQLAAEILSYKSQHPSE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SPWGRAGSLAKEQASVYTKLCGVFPPHLVEAVMGRFPQLLDPQQLAAEILSYKSQHPSE
550 560 570 580 590
>>NP_001310480 (OMIM: 610562) endoribonuclease ZC3H12A i (325 aa)
initn: 2314 init1: 2314 opt: 2314 Z-score: 1390.8 bits: 266.5 E(85289): 9.9e-71
Smith-Waterman score: 2314; 100.0% identity (100.0% similar) in 325 aa overlap (275-599:1-325)
250 260 270 280 290 300
pF1KE2 TYRDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLTLEHRKQ
::::::::::::::::::::::::::::::
NP_001 MPPDDPLGRHGPSLDNFLRKKPLTLEHRKQ
10 20 30
310 320 330 340 350 360
pF1KE2 PCPYGRKCTYGIKCRFFHPERPSCPQRSVADELRANALLSPPRAPSKDKNGRRPSPSSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCPYGRKCTYGIKCRFFHPERPSCPQRSVADELRANALLSPPRAPSKDKNGRRPSPSSQS
40 50 60 70 80 90
370 380 390 400 410 420
pF1KE2 SSLLTESEQCSLDGKKLGAQASPGSRQEGLTQTYAPSGRSLAPSGGSGSSFGPTDWLPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLLTESEQCSLDGKKLGAQASPGSRQEGLTQTYAPSGRSLAPSGGSGSSFGPTDWLPQT
100 110 120 130 140 150
430 440 450 460 470 480
pF1KE2 LDSLPYVSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPATAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDSLPYVSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPATAAF
160 170 180 190 200 210
490 500 510 520 530 540
pF1KE2 SAFGRAMGAGHFSVPADYPPAPPAFPPREYWSEPYPLPPPTSVLQEPPVQSPGAGRSPWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAFGRAMGAGHFSVPADYPPAPPAFPPREYWSEPYPLPPPTSVLQEPPVQSPGAGRSPWG
220 230 240 250 260 270
550 560 570 580 590
pF1KE2 RAGSLAKEQASVYTKLCGVFPPHLVEAVMGRFPQLLDPQQLAAEILSYKSQHPSE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAGSLAKEQASVYTKLCGVFPPHLVEAVMGRFPQLLDPQQLAAEILSYKSQHPSE
280 290 300 310 320
>>XP_011540500 (OMIM: 610562) PREDICTED: bifunctional en (394 aa)
initn: 1877 init1: 1852 opt: 1852 Z-score: 1116.3 bits: 216.0 E(85289): 1.9e-55
Smith-Waterman score: 1852; 99.6% identity (100.0% similar) in 274 aa overlap (1-274:1-274)
10 20 30 40 50 60
pF1KE2 MSGPCGEKPVLEASPTMSLWEFEDSHSRQGTPRPGQELAAEEASALELQMKVDFFRKLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSGPCGEKPVLEASPTMSLWEFEDSHSRQGTPRPGQELAAEEASALELQMKVDFFRKLGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SSTEIHSVLQKLGVQADTNTVLGELVKHGTATERERQTSPDPCPQLPLVPRGGGTPKAPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSTEIHSVLQKLGVQADTNTVLGELVKHGTATERERQTSPDPCPQLPLVPRGGGTPKAPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LEPPLPEEEKEGSDLRPVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEPPLPEEEKEGSDLRPVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SWRKEQPRPDVPITDQHILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAYESDGIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWRKEQPRPDVPITDQHILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAYESDGIV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VSNDTYRDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLTLE
:::::::::::::::::::::::::::::::::.
XP_011 VSNDTYRDLQGERQEWKRFIEERLLMYSFVNDKLAIGPFSAIRSPCMAPTSREFFAPSAG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 HRKQPCPYGRKCTYGIKCRFFHPERPSCPQRSVADELRANALLSPPRAPSKDKNGRRPSP
XP_011 LCPLMTHWAGTGPAWTTSCVRSHSLWSTGSSRVPMEGNAPMGSSADSSTQSGQAAPSALW
310 320 330 340 350 360
>>XP_011541357 (OMIM: 615001) PREDICTED: probable ribonu (852 aa)
initn: 1534 init1: 1247 opt: 1395 Z-score: 841.4 bits: 166.2 E(85289): 4e-40
Smith-Waterman score: 1423; 53.0% identity (71.5% similar) in 445 aa overlap (4-423:93-525)
10 20 30
pF1KE2 MSGPCGEKPVLEASPTMSLWEFEDSHSRQGTPR
:: : .:. . .. .. :.:.. . .
XP_011 TNSDHESEQLGSISVEPGLITKTHRQLCRSPCLEPHILKRNEILQDFKPEESQTTSKEAK
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE2 PGQELAAEEASALELQMKVDFFRKLGYSSTEIHSVLQKLGVQADTNTVLGELVKHGTATE
... : : :..: ::::: ... ::.:::..: : .:::::: :. .:
XP_011 KPPDVVRE------YQTKLEFALKLGYSEEQVQLVLNKLGTDALINDILGELVKLGNKSE
130 140 150 160 170
100 110 120 130 140 150
pF1KE2 RERQTSPDPCPQLPLVPRGGGTPKAPNLEPPLPE-EEKEGSDLRPVVIDGSNVAMSHGNK
.. .: . . : .. .. : :. : .: .:::.::::::::::::::
XP_011 ADQTVST-----INTITRETSSLESQRSESPMQEIVTDDGENLRPIVIDGSNVAMSHGNK
180 190 200 210 220 230
160 170 180 190 200 210
pF1KE2 EVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQPRPDVPITDQHILRELEKKKILVFTP
:::::::: :::.::::::: :::::::.::::: :::. ::::.:::.:::.:::::::
XP_011 EVFSCRGIKLAVDWFLERGHKDITVFVPAWRKEQSRPDALITDQEILRKLEKEKILVFTP
240 250 260 270 280 290
220 230 240 250 260 270
pF1KE2 SRRVGGKRVVCYDDRFIVKLAYESDGIVVSNDTYRDLQGERQEWKRFIEERLLMYSFVND
:::: :.::::::::::::::.:::::.::::.:::: .:. :::.::.:::::::::::
XP_011 SRRVQGRRVVCYDDRFIVKLAFESDGIIVSNDNYRDLANEKPEWKKFIDERLLMYSFVND
300 310 320 330 340 350
280 290 300 310 320 330
pF1KE2 KFMPPDDPLGRHGPSLDNFLRKKPLTLEHRKQPCPYGRKCTYGIKCRFFHPERPSCPQRS
::::::::::::::::::::::::.. ::.:::::::.::::: ::...:::: : ::::
XP_011 KFMPPDDPLGRHGPSLDNFLRKKPIVPEHKKQPCPYGKKCTYGHKCKYYHPERGSQPQRS
360 370 380 390 400 410
340 350 360 370
pF1KE2 VADELRA------------NALLSPPRAPSKDKNG-----RRPSPSSQSS-SLLTESEQC
::::::: ..:.. .: . : .: .:. ::. :. :. :
XP_011 VADELRAMSRNTAAKTANEGGLVKSNSVPCSTKADSTSDVKRGAPKRQSDPSIRTQVYQ-
420 430 440 450 460 470
380 390 400 410 420
pF1KE2 SLDGK-----KLGAQASPGSRQEGLTQTYAP-SGRSLAPSGGSGSSFGPTDWLPQTLDSL
.:. : :: ... :. . :.: : : ::. . :: : : : ::
XP_011 DLEEKLPTKNKLETRSVPSLVSIPATSTAKPQSTTSLSNGLPSGVHFPPQDQRPQGQYPS
480 490 500 510 520 530
430 440 450 460 470 480
pF1KE2 PYVSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPATAAFSAFG
XP_011 MMMATKNHGTPMPYEQYPKCDSPVDIGYYSMLNAYSNLSLSGPRSPERRFSLDTDYRISS
540 550 560 570 580 590
>>NP_203748 (OMIM: 615001) probable ribonuclease ZC3H12C (883 aa)
initn: 1534 init1: 1247 opt: 1395 Z-score: 841.2 bits: 166.2 E(85289): 4.1e-40
Smith-Waterman score: 1423; 53.0% identity (71.5% similar) in 445 aa overlap (4-423:124-556)
10 20 30
pF1KE2 MSGPCGEKPVLEASPTMSLWEFEDSHSRQGTPR
:: : .:. . .. .. :.:.. . .
NP_203 TNSDHESEQLGSISVEPGLITKTHRQLCRSPCLEPHILKRNEILQDFKPEESQTTSKEAK
100 110 120 130 140 150
40 50 60 70 80 90
pF1KE2 PGQELAAEEASALELQMKVDFFRKLGYSSTEIHSVLQKLGVQADTNTVLGELVKHGTATE
... : : :..: ::::: ... ::.:::..: : .:::::: :. .:
NP_203 KPPDVVRE------YQTKLEFALKLGYSEEQVQLVLNKLGTDALINDILGELVKLGNKSE
160 170 180 190 200
100 110 120 130 140 150
pF1KE2 RERQTSPDPCPQLPLVPRGGGTPKAPNLEPPLPE-EEKEGSDLRPVVIDGSNVAMSHGNK
.. .: . . : .. .. : :. : .: .:::.::::::::::::::
NP_203 ADQTVST-----INTITRETSSLESQRSESPMQEIVTDDGENLRPIVIDGSNVAMSHGNK
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE2 EVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQPRPDVPITDQHILRELEKKKILVFTP
:::::::: :::.::::::: :::::::.::::: :::. ::::.:::.:::.:::::::
NP_203 EVFSCRGIKLAVDWFLERGHKDITVFVPAWRKEQSRPDALITDQEILRKLEKEKILVFTP
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE2 SRRVGGKRVVCYDDRFIVKLAYESDGIVVSNDTYRDLQGERQEWKRFIEERLLMYSFVND
:::: :.::::::::::::::.:::::.::::.:::: .:. :::.::.:::::::::::
NP_203 SRRVQGRRVVCYDDRFIVKLAFESDGIIVSNDNYRDLANEKPEWKKFIDERLLMYSFVND
330 340 350 360 370 380
280 290 300 310 320 330
pF1KE2 KFMPPDDPLGRHGPSLDNFLRKKPLTLEHRKQPCPYGRKCTYGIKCRFFHPERPSCPQRS
::::::::::::::::::::::::.. ::.:::::::.::::: ::...:::: : ::::
NP_203 KFMPPDDPLGRHGPSLDNFLRKKPIVPEHKKQPCPYGKKCTYGHKCKYYHPERGSQPQRS
390 400 410 420 430 440
340 350 360 370
pF1KE2 VADELRA------------NALLSPPRAPSKDKNG-----RRPSPSSQSS-SLLTESEQC
::::::: ..:.. .: . : .: .:. ::. :. :. :
NP_203 VADELRAMSRNTAAKTANEGGLVKSNSVPCSTKADSTSDVKRGAPKRQSDPSIRTQVYQ-
450 460 470 480 490 500
380 390 400 410 420
pF1KE2 SLDGK-----KLGAQASPGSRQEGLTQTYAP-SGRSLAPSGGSGSSFGPTDWLPQTLDSL
.:. : :: ... :. . :.: : : ::. . :: : : : ::
NP_203 DLEEKLPTKNKLETRSVPSLVSIPATSTAKPQSTTSLSNGLPSGVHFPPQDQRPQGQYPS
510 520 530 540 550 560
430 440 450 460 470 480
pF1KE2 PYVSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPATAAFSAFG
NP_203 MMMATKNHGTPMPYEQYPKCDSPVDIGYYSMLNAYSNLSLSGPRSPERRFSLDTDYRISS
570 580 590 600 610 620
>>XP_005271772 (OMIM: 615001) PREDICTED: probable ribonu (884 aa)
initn: 1534 init1: 1247 opt: 1395 Z-score: 841.2 bits: 166.2 E(85289): 4.1e-40
Smith-Waterman score: 1423; 53.0% identity (71.5% similar) in 445 aa overlap (4-423:125-557)
10 20 30
pF1KE2 MSGPCGEKPVLEASPTMSLWEFEDSHSRQGTPR
:: : .:. . .. .. :.:.. . .
XP_005 TNSDHESEQLGSISVEPGLITKTHRQLCRSPCLEPHILKRNEILQDFKPEESQTTSKEAK
100 110 120 130 140 150
40 50 60 70 80 90
pF1KE2 PGQELAAEEASALELQMKVDFFRKLGYSSTEIHSVLQKLGVQADTNTVLGELVKHGTATE
... : : :..: ::::: ... ::.:::..: : .:::::: :. .:
XP_005 KPPDVVRE------YQTKLEFALKLGYSEEQVQLVLNKLGTDALINDILGELVKLGNKSE
160 170 180 190 200
100 110 120 130 140 150
pF1KE2 RERQTSPDPCPQLPLVPRGGGTPKAPNLEPPLPE-EEKEGSDLRPVVIDGSNVAMSHGNK
.. .: . . : .. .. : :. : .: .:::.::::::::::::::
XP_005 ADQTVST-----INTITRETSSLESQRSESPMQEIVTDDGENLRPIVIDGSNVAMSHGNK
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE2 EVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQPRPDVPITDQHILRELEKKKILVFTP
:::::::: :::.::::::: :::::::.::::: :::. ::::.:::.:::.:::::::
XP_005 EVFSCRGIKLAVDWFLERGHKDITVFVPAWRKEQSRPDALITDQEILRKLEKEKILVFTP
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE2 SRRVGGKRVVCYDDRFIVKLAYESDGIVVSNDTYRDLQGERQEWKRFIEERLLMYSFVND
:::: :.::::::::::::::.:::::.::::.:::: .:. :::.::.:::::::::::
XP_005 SRRVQGRRVVCYDDRFIVKLAFESDGIIVSNDNYRDLANEKPEWKKFIDERLLMYSFVND
330 340 350 360 370 380
280 290 300 310 320 330
pF1KE2 KFMPPDDPLGRHGPSLDNFLRKKPLTLEHRKQPCPYGRKCTYGIKCRFFHPERPSCPQRS
::::::::::::::::::::::::.. ::.:::::::.::::: ::...:::: : ::::
XP_005 KFMPPDDPLGRHGPSLDNFLRKKPIVPEHKKQPCPYGKKCTYGHKCKYYHPERGSQPQRS
390 400 410 420 430 440
340 350 360 370
pF1KE2 VADELRA------------NALLSPPRAPSKDKNG-----RRPSPSSQSS-SLLTESEQC
::::::: ..:.. .: . : .: .:. ::. :. :. :
XP_005 VADELRAMSRNTAAKTANEGGLVKSNSVPCSTKADSTSDVKRGAPKRQSDPSIRTQVYQ-
450 460 470 480 490 500
380 390 400 410 420
pF1KE2 SLDGK-----KLGAQASPGSRQEGLTQTYAP-SGRSLAPSGGSGSSFGPTDWLPQTLDSL
.:. : :: ... :. . :.: : : ::. . :: : : : ::
XP_005 DLEEKLPTKNKLETRSVPSLVSIPATSTAKPQSTTSLSNGLPSGVHFPPQDQRPQGQYPS
510 520 530 540 550 560
430 440 450 460 470 480
pF1KE2 PYVSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPATAAFSAFG
XP_005 MMMATKNHGTPMPYEQYPKCDSPVDIGYYSMLNAYSNLSLSGPRSPERRFSLDTDYRISS
570 580 590 600 610 620
>>XP_016873966 (OMIM: 615001) PREDICTED: probable ribonu (884 aa)
initn: 1534 init1: 1247 opt: 1395 Z-score: 841.2 bits: 166.2 E(85289): 4.1e-40
Smith-Waterman score: 1423; 53.0% identity (71.5% similar) in 445 aa overlap (4-423:125-557)
10 20 30
pF1KE2 MSGPCGEKPVLEASPTMSLWEFEDSHSRQGTPR
:: : .:. . .. .. :.:.. . .
XP_016 TNSDHESEQLGSISVEPGLITKTHRQLCRSPCLEPHILKRNEILQDFKPEESQTTSKEAK
100 110 120 130 140 150
40 50 60 70 80 90
pF1KE2 PGQELAAEEASALELQMKVDFFRKLGYSSTEIHSVLQKLGVQADTNTVLGELVKHGTATE
... : : :..: ::::: ... ::.:::..: : .:::::: :. .:
XP_016 KPPDVVRE------YQTKLEFALKLGYSEEQVQLVLNKLGTDALINDILGELVKLGNKSE
160 170 180 190 200
100 110 120 130 140 150
pF1KE2 RERQTSPDPCPQLPLVPRGGGTPKAPNLEPPLPE-EEKEGSDLRPVVIDGSNVAMSHGNK
.. .: . . : .. .. : :. : .: .:::.::::::::::::::
XP_016 ADQTVST-----INTITRETSSLESQRSESPMQEIVTDDGENLRPIVIDGSNVAMSHGNK
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE2 EVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQPRPDVPITDQHILRELEKKKILVFTP
:::::::: :::.::::::: :::::::.::::: :::. ::::.:::.:::.:::::::
XP_016 EVFSCRGIKLAVDWFLERGHKDITVFVPAWRKEQSRPDALITDQEILRKLEKEKILVFTP
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE2 SRRVGGKRVVCYDDRFIVKLAYESDGIVVSNDTYRDLQGERQEWKRFIEERLLMYSFVND
:::: :.::::::::::::::.:::::.::::.:::: .:. :::.::.:::::::::::
XP_016 SRRVQGRRVVCYDDRFIVKLAFESDGIIVSNDNYRDLANEKPEWKKFIDERLLMYSFVND
330 340 350 360 370 380
280 290 300 310 320 330
pF1KE2 KFMPPDDPLGRHGPSLDNFLRKKPLTLEHRKQPCPYGRKCTYGIKCRFFHPERPSCPQRS
::::::::::::::::::::::::.. ::.:::::::.::::: ::...:::: : ::::
XP_016 KFMPPDDPLGRHGPSLDNFLRKKPIVPEHKKQPCPYGKKCTYGHKCKYYHPERGSQPQRS
390 400 410 420 430 440
340 350 360 370
pF1KE2 VADELRA------------NALLSPPRAPSKDKNG-----RRPSPSSQSS-SLLTESEQC
::::::: ..:.. .: . : .: .:. ::. :. :. :
XP_016 VADELRAMSRNTAAKTANEGGLVKSNSVPCSTKADSTSDVKRGAPKRQSDPSIRTQVYQ-
450 460 470 480 490 500
380 390 400 410 420
pF1KE2 SLDGK-----KLGAQASPGSRQEGLTQTYAP-SGRSLAPSGGSGSSFGPTDWLPQTLDSL
.:. : :: ... :. . :.: : : ::. . :: : : : ::
XP_016 DLEEKLPTKNKLETRSVPSLVSIPATSTAKPQSTTSLSNGLPSGVHFPPQDQRPQGQYPS
510 520 530 540 550 560
430 440 450 460 470 480
pF1KE2 PYVSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPATAAFSAFG
XP_016 MMMATKNHGTPMPYEQYPKCDSPVDIGYYSMLNAYSNLSLSGPRSPERRFSLDTDYRISS
570 580 590 600 610 620
>>XP_016884969 (OMIM: 300889) PREDICTED: probable ribonu (836 aa)
initn: 1501 init1: 1274 opt: 1384 Z-score: 835.0 bits: 165.0 E(85289): 9e-40
Smith-Waterman score: 1384; 59.2% identity (78.0% similar) in 368 aa overlap (47-408:107-464)
20 30 40 50 60 70
pF1KE2 MSLWEFEDSHSRQGTPRPGQELAAEEASALELQMKVDFFRKLGYSSTEIHSVLQKLGVQA
: : :..: ::::. .:.:::.::: ..
XP_016 HRQLCRSPCLDRPSFSQSSILQDGKLDLEKEYQAKMEFALKLGYAEEQIQSVLNKLGPES
80 90 100 110 120 130
80 90 100 110 120 130
pF1KE2 DTNTVLGELVKHGTATERERQTSPDPCPQLPLVPRGGGTPKAPNLEPPLPEEEKEGSDLR
: ::.:::. :. . : : . . ::::: .. . . : : .: ....::
XP_016 LINDVLAELVRLGNKGDSEGQINLSL-----LVPRGPSSREIASPELSLEDEIDNSDNLR
140 150 160 170 180 190
140 150 160 170 180 190
pF1KE2 PVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQPRPDVPITDQ
::::::::::::::::: :::::: :::.:::..:: :::::::.::::: :::.:::::
XP_016 PVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQ
200 210 220 230 240 250
200 210 220 230 240 250
pF1KE2 HILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAYESDGIVVSNDTYRDLQGERQEW
:::.:::.::::::::::: :.::::::::::::::..::::.::::.::::: :. ::
XP_016 DILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEW
260 270 280 290 300 310
260 270 280 290 300 310
pF1KE2 KRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLTLEHRKQPCPYGRKCTYGI
:.::::::::::::::::::::::::::::::.:::::.:.. ::.:::::::.:::::
XP_016 KKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPIVPEHKKQPCPYGKKCTYGH
320 330 340 350 360 370
320 330 340 350 360 370
pF1KE2 KCRFFHPERPSCPQRSVADELRANALLSPPRAPSKDKNGRRPSPSSQSSSLLTESEQCSL
::...:::: . :::::::::: .: :: .. :. .. . :.... .: :: .
XP_016 KCKYYHPERANQPQRSVADELRISAKLSTVKTMSEGTLAKCGTGMSSAKGEIT-SEVKRV
380 390 400 410 420 430
380 390 400 410 420 430
pF1KE2 DGKKLGAQASPGSR------QEGLTQTYAPSGRSLAPSGGSGSSFGPTDWLPQTLDSLPY
:. :..:. : .: :. . : . :. ::
XP_016 APKR---QSDPSIRSVAMEPEEWLSIARKPEASSV-PSLVTALSVPTIPPPKSHAVGALN
440 450 460 470 480
440 450 460 470 480 490
pF1KE2 VSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPATAAFSAFGRA
XP_016 TRSASSPVPGSSHFPHQKASLEHMASMQYPPILVTNSHGTPISYAEQYPKFESMGDHGYY
490 500 510 520 530 540
>>XP_016884968 (OMIM: 300889) PREDICTED: probable ribonu (836 aa)
initn: 1501 init1: 1274 opt: 1384 Z-score: 835.0 bits: 165.0 E(85289): 9e-40
Smith-Waterman score: 1384; 59.2% identity (78.0% similar) in 368 aa overlap (47-408:107-464)
20 30 40 50 60 70
pF1KE2 MSLWEFEDSHSRQGTPRPGQELAAEEASALELQMKVDFFRKLGYSSTEIHSVLQKLGVQA
: : :..: ::::. .:.:::.::: ..
XP_016 HRQLCRSPCLDRPSFSQSSILQDGKLDLEKEYQAKMEFALKLGYAEEQIQSVLNKLGPES
80 90 100 110 120 130
80 90 100 110 120 130
pF1KE2 DTNTVLGELVKHGTATERERQTSPDPCPQLPLVPRGGGTPKAPNLEPPLPEEEKEGSDLR
: ::.:::. :. . : : . . ::::: .. . . : : .: ....::
XP_016 LINDVLAELVRLGNKGDSEGQINLSL-----LVPRGPSSREIASPELSLEDEIDNSDNLR
140 150 160 170 180 190
140 150 160 170 180 190
pF1KE2 PVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQPRPDVPITDQ
::::::::::::::::: :::::: :::.:::..:: :::::::.::::: :::.:::::
XP_016 PVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQ
200 210 220 230 240 250
200 210 220 230 240 250
pF1KE2 HILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAYESDGIVVSNDTYRDLQGERQEW
:::.:::.::::::::::: :.::::::::::::::..::::.::::.::::: :. ::
XP_016 DILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEW
260 270 280 290 300 310
260 270 280 290 300 310
pF1KE2 KRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLTLEHRKQPCPYGRKCTYGI
:.::::::::::::::::::::::::::::::.:::::.:.. ::.:::::::.:::::
XP_016 KKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPIVPEHKKQPCPYGKKCTYGH
320 330 340 350 360 370
320 330 340 350 360 370
pF1KE2 KCRFFHPERPSCPQRSVADELRANALLSPPRAPSKDKNGRRPSPSSQSSSLLTESEQCSL
::...:::: . :::::::::: .: :: .. :. .. . :.... .: :: .
XP_016 KCKYYHPERANQPQRSVADELRISAKLSTVKTMSEGTLAKCGTGMSSAKGEIT-SEVKRV
380 390 400 410 420 430
380 390 400 410 420 430
pF1KE2 DGKKLGAQASPGSR------QEGLTQTYAPSGRSLAPSGGSGSSFGPTDWLPQTLDSLPY
:. :..:. : .: :. . : . :. ::
XP_016 APKR---QSDPSIRSVAMEPEEWLSIARKPEASSV-PSLVTALSVPTIPPPKSHAVGALN
440 450 460 470 480
440 450 460 470 480 490
pF1KE2 VSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPATAAFSAFGRA
XP_016 TRSASSPVPGSSHFPHQKASLEHMASMQYPPILVTNSHGTPISYAEQYPKFESMGDHGYY
490 500 510 520 530 540
599 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:22:19 2016 done: Sun Nov 6 19:22:21 2016
Total Scan time: 13.730 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]