Result of FASTA (omim) for
pFN21AE2014
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2014, 592 aa
1>>>pF1KE2014 592 - 592 aa - 592 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4482+/-0.000575; mu= 6.5329+/- 0.035
mean_var=295.2593+/-62.072, 0's: 0 Z-trim(116.1): 42 B-trim: 889 in 1/52
Lambda= 0.074640
statistics sampled from 27037 (27077) to 27037 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.317), width: 16
Scan time: 8.330
The best scores are: opt bits E(85289)
NP_006759 (OMIM: 604986) BRCA1-associated protein ( 592) 3936 438.2 3.6e-122
XP_005254001 (OMIM: 604986) PREDICTED: BRCA1-assoc ( 633) 3768 420.2 1e-116
XP_016875481 (OMIM: 604986) PREDICTED: BRCA1-assoc ( 538) 3429 383.6 9.2e-106
XP_016875482 (OMIM: 604986) PREDICTED: BRCA1-assoc ( 443) 2980 335.1 2.9e-91
XP_016875484 (OMIM: 604986) PREDICTED: BRCA1-assoc ( 443) 2980 335.1 2.9e-91
XP_016875483 (OMIM: 604986) PREDICTED: BRCA1-assoc ( 443) 2980 335.1 2.9e-91
XP_011537091 (OMIM: 604986) PREDICTED: BRCA1-assoc ( 305) 1976 226.8 8.1e-59
>>NP_006759 (OMIM: 604986) BRCA1-associated protein [Hom (592 aa)
initn: 3936 init1: 3936 opt: 3936 Z-score: 2314.4 bits: 438.2 E(85289): 3.6e-122
Smith-Waterman score: 3936; 100.0% identity (100.0% similar) in 592 aa overlap (1-592:1-592)
10 20 30 40 50 60
pF1KE2 MSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 HQHLGRREMTDVIIETMKSNPDELKTTVEERKSSEASPTAQRSKDHSKECINAAPDSPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HQHLGRREMTDVIIETMKSNPDELKTTVEERKSSEASPTAQRSKDHSKECINAAPDSPSK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 QLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMKF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 RAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 PVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 IYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYL
490 500 510 520 530 540
550 560 570 580 590
pF1KE2 ETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK
550 560 570 580 590
>>XP_005254001 (OMIM: 604986) PREDICTED: BRCA1-associate (633 aa)
initn: 3922 init1: 3768 opt: 3768 Z-score: 2216.3 bits: 420.2 E(85289): 1e-116
Smith-Waterman score: 3795; 93.4% identity (93.4% similar) in 624 aa overlap (10-592:10-633)
10 20
pF1KE2 MSVSLVVIRLELAEHSPVPAGFGFSAA---------------------------------
::::::::::::::::::
XP_005 MSVSLVVIRLELAEHSPVPAGFGFSAAGESRGLAAFPVAGSGPGGLPFPKHWPGKSPRRG
10 20 30 40 50 60
30 40 50 60 70
pF1KE2 --------AGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIHQHLGRREMTDVIIETMKS
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLPRKTRRAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIHQHLGRREMTDVIIETMKS
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE2 NPDELKTTVEERKSSEASPTAQRSKDHSKECINAAPDSPSKQLPDQISFFSGNPSVEIVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NPDELKTTVEERKSSEASPTAQRSKDHSKECINAAPDSPSKQLPDQISFFSGNPSVEIVH
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE2 GIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMKFVAPFNEVIEQMKIIRDSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMKFVAPFNEVIEQMKIIRDSTP
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE2 NQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYVERAEVLKSEDGASLPVMDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYVERAEVLKSEDGASLPVMDLT
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE2 ELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTCPVCRYCQTPEPVEENKCFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTCPVCRYCQTPEPVEENKCFE
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE2 CGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHRLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHRLVA
370 380 390 400 410 420
380 390 400 410 420 430
pF1KE2 SKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEIN
430 440 450 460 470 480
440 450 460 470 480 490
pF1KE2 NMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRA
490 500 510 520 530 540
500 510 520 530 540 550
pF1KE2 NQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQE
550 560 570 580 590 600
560 570 580 590
pF1KE2 GQINIAMASASSPASSGGSGKLPSRKGRSKRGK
:::::::::::::::::::::::::::::::::
XP_005 GQINIAMASASSPASSGGSGKLPSRKGRSKRGK
610 620 630
>>XP_016875481 (OMIM: 604986) PREDICTED: BRCA1-associate (538 aa)
initn: 3429 init1: 3429 opt: 3429 Z-score: 2019.8 bits: 383.6 E(85289): 9.2e-106
Smith-Waterman score: 3476; 90.9% identity (90.9% similar) in 592 aa overlap (1-592:1-538)
10 20 30 40 50 60
pF1KE2 MSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAII
:::::::::::::::::::::::::::
XP_016 MSVSLVVIRLELAEHSPVPAGFGFSAA---------------------------------
10 20
70 80 90 100 110 120
pF1KE2 HQHLGRREMTDVIIETMKSNPDELKTTVEERKSSEASPTAQRSKDHSKECINAAPDSPSK
:::::::::::::::::::::::::::::::::::::::
XP_016 ---------------------DELKTTVEERKSSEASPTAQRSKDHSKECINAAPDSPSK
30 40 50 60
130 140 150 160 170 180
pF1KE2 QLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMKF
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE2 VAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYVE
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE2 RAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTC
190 200 210 220 230 240
310 320 330 340 350 360
pF1KE2 PVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQL
250 260 270 280 290 300
370 380 390 400 410 420
pF1KE2 TNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQR
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE2 IYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKV
370 380 390 400 410 420
490 500 510 520 530 540
pF1KE2 AKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYL
430 440 450 460 470 480
550 560 570 580 590
pF1KE2 ETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK
490 500 510 520 530
>>XP_016875482 (OMIM: 604986) PREDICTED: BRCA1-associate (443 aa)
initn: 2980 init1: 2980 opt: 2980 Z-score: 1759.4 bits: 335.1 E(85289): 2.9e-91
Smith-Waterman score: 2980; 100.0% identity (100.0% similar) in 443 aa overlap (150-592:1-443)
120 130 140 150 160 170
pF1KE2 KQLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMK
::::::::::::::::::::::::::::::
XP_016 MTSLKEDVRRSAMLCILTVPAAMTSHDLMK
10 20 30
180 190 200 210 220 230
pF1KE2 FVAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYV
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE2 ERAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTT
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE2 CPVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQ
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE2 LTNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQ
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE2 RIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTK
280 290 300 310 320 330
480 490 500 510 520 530
pF1KE2 VAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFY
340 350 360 370 380 390
540 550 560 570 580 590
pF1KE2 LETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK
400 410 420 430 440
>>XP_016875484 (OMIM: 604986) PREDICTED: BRCA1-associate (443 aa)
initn: 2980 init1: 2980 opt: 2980 Z-score: 1759.4 bits: 335.1 E(85289): 2.9e-91
Smith-Waterman score: 2980; 100.0% identity (100.0% similar) in 443 aa overlap (150-592:1-443)
120 130 140 150 160 170
pF1KE2 KQLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMK
::::::::::::::::::::::::::::::
XP_016 MTSLKEDVRRSAMLCILTVPAAMTSHDLMK
10 20 30
180 190 200 210 220 230
pF1KE2 FVAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYV
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE2 ERAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTT
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE2 CPVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQ
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE2 LTNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQ
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE2 RIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTK
280 290 300 310 320 330
480 490 500 510 520 530
pF1KE2 VAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFY
340 350 360 370 380 390
540 550 560 570 580 590
pF1KE2 LETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK
400 410 420 430 440
>>XP_016875483 (OMIM: 604986) PREDICTED: BRCA1-associate (443 aa)
initn: 2980 init1: 2980 opt: 2980 Z-score: 1759.4 bits: 335.1 E(85289): 2.9e-91
Smith-Waterman score: 2980; 100.0% identity (100.0% similar) in 443 aa overlap (150-592:1-443)
120 130 140 150 160 170
pF1KE2 KQLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMK
::::::::::::::::::::::::::::::
XP_016 MTSLKEDVRRSAMLCILTVPAAMTSHDLMK
10 20 30
180 190 200 210 220 230
pF1KE2 FVAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYV
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE2 ERAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTT
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE2 CPVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQ
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE2 LTNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQ
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE2 RIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTK
280 290 300 310 320 330
480 490 500 510 520 530
pF1KE2 VAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFY
340 350 360 370 380 390
540 550 560 570 580 590
pF1KE2 LETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK
400 410 420 430 440
>>XP_011537091 (OMIM: 604986) PREDICTED: BRCA1-associate (305 aa)
initn: 1976 init1: 1976 opt: 1976 Z-score: 1177.0 bits: 226.8 E(85289): 8.1e-59
Smith-Waterman score: 1976; 100.0% identity (100.0% similar) in 293 aa overlap (300-592:13-305)
270 280 290 300 310 320
pF1KE2 RMDESVNGILTTLCNHSFHSQCLQRWDDTTCPVCRYCQTPEPVEENKCFECGVQENLWIC
::::::::::::::::::::::::::::::
XP_011 MWKELKCSNLKMCPVCRYCQTPEPVEENKCFECGVQENLWIC
10 20 30 40
330 340 350 360 370 380
pF1KE2 LICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHRLVASKTDGKIVQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHRLVASKTDGKIVQY
50 60 70 80 90 100
390 400 410 420 430 440
pF1KE2 ECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETI
110 120 130 140 150 160
450 460 470 480 490 500
pF1KE2 EKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLK
170 180 190 200 210 220
510 520 530 540 550 560
pF1KE2 EEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQEGQINIAMASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQEGQINIAMASA
230 240 250 260 270 280
570 580 590
pF1KE2 SSPASSGGSGKLPSRKGRSKRGK
:::::::::::::::::::::::
XP_011 SSPASSGGSGKLPSRKGRSKRGK
290 300
592 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:42:36 2016 done: Sun Nov 6 14:42:37 2016
Total Scan time: 8.330 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]