Result of FASTA (omim) for
pFN21AE2011
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2011, 590 aa
1>>>pF1KE2011 590 - 590 aa - 590 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1760+/-0.000546; mu= 6.6897+/- 0.033
mean_var=512.7504+/-116.548, 0's: 0 Z-trim(117.2): 1622 B-trim: 36 in 1/53
Lambda= 0.056640
statistics sampled from 26859 (29078) to 26859 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.341), width: 16
Scan time: 8.750
The best scores are: opt bits E(85289)
NP_005299 (OMIM: 600870) G protein-coupled recepto ( 590) 4022 344.6 5.3e-94
XP_005269765 (OMIM: 600870) PREDICTED: G protein-c ( 558) 3700 318.3 4.3e-86
NP_002073 (OMIM: 600869) G protein-coupled recepto ( 589) 2836 247.7 7.9e-65
NP_001004105 (OMIM: 600869) G protein-coupled rece ( 560) 2831 247.3 1e-64
NP_001004106 (OMIM: 600869) G protein-coupled rece ( 576) 2831 247.3 1e-64
NP_892027 (OMIM: 137026) G protein-coupled recepto ( 578) 2662 233.5 1.5e-60
XP_006714922 (OMIM: 600869) PREDICTED: G protein-c ( 557) 2643 231.9 4.3e-60
XP_006714921 (OMIM: 600869) PREDICTED: G protein-c ( 559) 2555 224.7 6.3e-58
NP_001004057 (OMIM: 137026) G protein-coupled rece ( 532) 2541 223.5 1.4e-57
NP_001004056 (OMIM: 137026) G protein-coupled rece ( 546) 2426 214.2 9.3e-55
XP_011532839 (OMIM: 600869) PREDICTED: G protein-c ( 550) 2376 210.1 1.6e-53
NP_005298 (OMIM: 137026) G protein-coupled recepto ( 500) 2305 204.2 8.5e-52
XP_005269764 (OMIM: 600870) PREDICTED: G protein-c ( 560) 2187 194.7 7.1e-49
XP_016863545 (OMIM: 137026) PREDICTED: G protein-c ( 440) 2064 184.4 6.8e-46
XP_016863543 (OMIM: 137026) PREDICTED: G protein-c ( 486) 2064 184.5 7.1e-46
XP_016863549 (OMIM: 137026) PREDICTED: G protein-c ( 384) 1839 165.9 2.2e-40
XP_016863548 (OMIM: 137026) PREDICTED: G protein-c ( 384) 1839 165.9 2.2e-40
XP_016863547 (OMIM: 137026) PREDICTED: G protein-c ( 384) 1839 165.9 2.2e-40
XP_016863546 (OMIM: 137026) PREDICTED: G protein-c ( 384) 1839 165.9 2.2e-40
XP_011511751 (OMIM: 137026) PREDICTED: G protein-c ( 585) 1841 166.4 2.4e-40
XP_016863544 (OMIM: 137026) PREDICTED: G protein-c ( 454) 1828 165.2 4.4e-40
XP_016863541 (OMIM: 137026) PREDICTED: G protein-c ( 591) 1830 165.5 4.4e-40
XP_011511750 (OMIM: 137026) PREDICTED: G protein-c ( 611) 1830 165.5 4.5e-40
XP_011511749 (OMIM: 137026) PREDICTED: G protein-c ( 617) 1830 165.6 4.5e-40
NP_002920 (OMIM: 180381,613411) rhodopsin kinase [ ( 563) 1758 159.6 2.6e-38
XP_006713943 (OMIM: 137026) PREDICTED: G protein-c ( 367) 1751 158.7 3.1e-38
XP_005248019 (OMIM: 137026) PREDICTED: G protein-c ( 367) 1751 158.7 3.1e-38
XP_016863551 (OMIM: 137026) PREDICTED: G protein-c ( 367) 1751 158.7 3.1e-38
XP_016863550 (OMIM: 137026) PREDICTED: G protein-c ( 367) 1751 158.7 3.1e-38
XP_016863552 (OMIM: 137026) PREDICTED: G protein-c ( 338) 1718 155.9 1.9e-37
XP_011511752 (OMIM: 137026) PREDICTED: G protein-c ( 571) 1709 155.6 4.1e-37
XP_016861206 (OMIM: 606987) PREDICTED: rhodopsin k ( 553) 1627 148.9 4.2e-35
NP_631948 (OMIM: 606987) rhodopsin kinase [Homo sa ( 553) 1627 148.9 4.2e-35
XP_011532840 (OMIM: 600869) PREDICTED: G protein-c ( 324) 1518 139.6 1.6e-32
XP_011511755 (OMIM: 137026) PREDICTED: G protein-c ( 525) 1454 134.7 7.4e-31
XP_016863555 (OMIM: 137026) PREDICTED: G protein-c ( 292) 1241 116.8 9.8e-26
XP_016863553 (OMIM: 137026) PREDICTED: G protein-c ( 338) 1241 117.0 1.1e-25
XP_011511757 (OMIM: 137026) PREDICTED: G protein-c ( 479) 1232 116.5 2.1e-25
XP_011511756 (OMIM: 137026) PREDICTED: G protein-c ( 525) 1232 116.6 2.1e-25
XP_011511754 (OMIM: 137026) PREDICTED: G protein-c ( 565) 1232 116.6 2.2e-25
XP_011511753 (OMIM: 137026) PREDICTED: G protein-c ( 571) 1232 116.6 2.2e-25
XP_016876173 (OMIM: 180381,613411) PREDICTED: rhod ( 328) 1148 109.3 2e-23
NP_001610 (OMIM: 109635) beta-adrenergic receptor ( 689) 1089 105.1 8e-22
NP_005151 (OMIM: 109636) beta-adrenergic receptor ( 688) 1081 104.4 1.3e-21
XP_011543075 (OMIM: 109635) PREDICTED: beta-adrene ( 659) 1071 103.6 2.2e-21
XP_011528277 (OMIM: 109636) PREDICTED: beta-adrene ( 523) 957 94.1 1.2e-18
XP_016863542 (OMIM: 137026) PREDICTED: G protein-c ( 587) 940 92.8 3.4e-18
XP_016863554 (OMIM: 137026) PREDICTED: G protein-c ( 290) 834 83.6 1e-15
XP_011511759 (OMIM: 137026) PREDICTED: G protein-c ( 306) 834 83.6 1e-15
XP_011511758 (OMIM: 137026) PREDICTED: G protein-c ( 370) 728 75.1 4.6e-13
>>NP_005299 (OMIM: 600870) G protein-coupled receptor ki (590 aa)
initn: 4022 init1: 4022 opt: 4022 Z-score: 1808.6 bits: 344.6 E(85289): 5.3e-94
Smith-Waterman score: 4022; 100.0% identity (100.0% similar) in 590 aa overlap (1-590:1-590)
10 20 30 40 50 60
pF1KE2 MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 EQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLNRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLNRN
490 500 510 520 530 540
550 560 570 580 590
pF1KE2 HPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS
550 560 570 580 590
>>XP_005269765 (OMIM: 600870) PREDICTED: G protein-coupl (558 aa)
initn: 3782 init1: 3699 opt: 3700 Z-score: 1666.6 bits: 318.3 E(85289): 4.3e-86
Smith-Waterman score: 3722; 94.6% identity (94.6% similar) in 590 aa overlap (1-590:1-558)
10 20 30 40 50 60
pF1KE2 MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ
::::::::::::::::: :::::::::::
XP_005 MELENIVANTVLLKARE--------------------------------DRDYCSLCDKQ
10 20
70 80 90 100 110 120
pF1KE2 PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ
30 40 50 60 70 80
130 140 150 160 170 180
pF1KE2 VGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQP
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE2 VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE2 DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE2 RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE2 KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE2 EQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLNRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLNRN
450 460 470 480 490 500
550 560 570 580 590
pF1KE2 HPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS
510 520 530 540 550
>>NP_002073 (OMIM: 600869) G protein-coupled receptor ki (589 aa)
initn: 2866 init1: 2729 opt: 2836 Z-score: 1284.8 bits: 247.7 E(85289): 7.9e-65
Smith-Waterman score: 2836; 70.9% identity (88.7% similar) in 573 aa overlap (1-572:1-573)
10 20 30 40 50 60
pF1KE2 MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ
:::::::::::::::::::::.::::::::...:.::::::::.:: ...::: :::..:
NP_002 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ
::::::::.:: ::: : . :::.:::::::::.: :... ..:. .: .: .
NP_002 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQP
: ..::.. ..: : :::.::. .. .:::: :: .::::..:.::::::::::::
NP_002 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
:::::::::::::::::::::::::::::::::::.::::::::::::.:::::::::::
NP_002 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE
:::.:::.::::::::::::::::.:::::::::::.::. :: : ::.:::::: ::::
NP_002 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ
::::: ::::::::::::::.::::::::::::..:::. :.:::::::::::::..:.
NP_002 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC
:: .:::.:.::::.:::: :::::. ::.:.:::::.: : :. : ::..:: .:.:.:
NP_002 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI
..:: :: .::::. .: :::.::.:...::::: ::::.::: :::.:.::::::::
NP_002 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI
430 440 450 460 470 480
490 500 510 520 530
pF1KE2 EQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLN-R
:::::::::.:. ::.:::.::.:::: :::::::.:::::.:::::: .:..::::. .
NP_002 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 NHPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS
..:: :::::::::::.::. .. . :.:
NP_002 GQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR
550 560 570 580
>>NP_001004105 (OMIM: 600869) G protein-coupled receptor (560 aa)
initn: 2866 init1: 2729 opt: 2831 Z-score: 1282.8 bits: 247.3 E(85289): 1e-64
Smith-Waterman score: 2831; 72.3% identity (89.6% similar) in 559 aa overlap (1-558:1-559)
10 20 30 40 50 60
pF1KE2 MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ
:::::::::::::::::::::.::::::::...:.::::::::.:: ...::: :::..:
NP_001 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ
::::::::.:: ::: : . :::.:::::::::.: :... ..:. .: .: .
NP_001 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQP
: ..::.. ..: : :::.::. .. .:::: :: .::::..:.::::::::::::
NP_001 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
:::::::::::::::::::::::::::::::::::.::::::::::::.:::::::::::
NP_001 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE
:::.:::.::::::::::::::::.:::::::::::.::. :: : ::.:::::: ::::
NP_001 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ
::::: ::::::::::::::.::::::::::::..:::. :.:::::::::::::..:.
NP_001 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC
:: .:::.:.::::.:::: :::::. ::.:.:::::.: : :. : ::..:: .:.:.:
NP_001 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI
..:: :: .::::. .: :::.::.:...::::: ::::.::: :::.:.::::::::
NP_001 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI
430 440 450 460 470 480
490 500 510 520 530
pF1KE2 EQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLN-R
:::::::::.:. ::.:::.::.:::: :::::::.:::::.:::::: .:..::::. .
NP_001 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 NHPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS
..:: :::::::::::.::
NP_001 GQPPAPPKKGLLQRLFSRQR
550 560
>>NP_001004106 (OMIM: 600869) G protein-coupled receptor (576 aa)
initn: 2866 init1: 2729 opt: 2831 Z-score: 1282.7 bits: 247.3 E(85289): 1e-64
Smith-Waterman score: 2831; 72.3% identity (89.6% similar) in 559 aa overlap (1-558:1-559)
10 20 30 40 50 60
pF1KE2 MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ
:::::::::::::::::::::.::::::::...:.::::::::.:: ...::: :::..:
NP_001 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ
::::::::.:: ::: : . :::.:::::::::.: :... ..:. .: .: .
NP_001 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQP
: ..::.. ..: : :::.::. .. .:::: :: .::::..:.::::::::::::
NP_001 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
:::::::::::::::::::::::::::::::::::.::::::::::::.:::::::::::
NP_001 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE
:::.:::.::::::::::::::::.:::::::::::.::. :: : ::.:::::: ::::
NP_001 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ
::::: ::::::::::::::.::::::::::::..:::. :.:::::::::::::..:.
NP_001 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC
:: .:::.:.::::.:::: :::::. ::.:.:::::.: : :. : ::..:: .:.:.:
NP_001 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI
..:: :: .::::. .: :::.::.:...::::: ::::.::: :::.:.::::::::
NP_001 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI
430 440 450 460 470 480
490 500 510 520 530
pF1KE2 EQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLN-R
:::::::::.:. ::.:::.::.:::: :::::::.:::::.:::::: .:..::::. .
NP_001 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 NHPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS
..:: :::::::::::.::
NP_001 GQPPAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL
550 560 570
>>NP_892027 (OMIM: 137026) G protein-coupled receptor ki (578 aa)
initn: 2620 init1: 2125 opt: 2662 Z-score: 1208.1 bits: 233.5 E(85289): 1.5e-60
Smith-Waterman score: 2662; 68.2% identity (87.9% similar) in 560 aa overlap (1-557:1-560)
10 20 30 40 50 60
pF1KE2 MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ
:::::::::..:::::.:: ::..:.:::::::: .: .::: .::..:..:: ::::::
NP_892 MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ
:::: ::::::.:.: :. .:.:::.::::::. :: .. : :. .... : . . .
NP_892 PIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPE
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 VGQDLVSQTEEKLLQK-PCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQ
. :.:.. . : .. : :. : :.. .:.:::::::.:: .: .:..::::::::::
NP_892 IPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQ
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILE
::::::::.:::::::::::::::::::::::::::.:.::::::::::.::::::.:::
NP_892 PVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 KVNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGL
::.:.:::.:::::::::::::::::::::::::::::.:::::.:.::.:::::. :::
NP_892 KVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 EDLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNN
:::.:: :::::::::::::: :::::::::::..::::. .::::::::::::::.::
NP_892 EDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNN
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 QRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSI
..: .:::.:::::::::::.:.:::. ::::: ::::.:. . : ::.::::.::::
NP_892 EKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSI
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 CKMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLD
:.:::::. ..::::. :::: ::.:: :...::.::::.::.::: :::.:::::::::
NP_892 CRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLD
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 IEQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLNR
:::::.:::. :: .:.:::..:.:: :::::::::::. :::..: . .:: ::..
NP_892 IEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEMIESGCFKDINKSESEEALPLDLDK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 N-HPPEP-PKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS
: : : :..:.. :::.:
NP_892 NIHTPVSRPNRGFFYRLFRRGGCLTMVPSEKEVEPKQC
550 560 570
>>XP_006714922 (OMIM: 600869) PREDICTED: G protein-coupl (557 aa)
initn: 2664 init1: 2527 opt: 2643 Z-score: 1199.8 bits: 231.9 E(85289): 4.3e-60
Smith-Waterman score: 2643; 69.7% identity (88.0% similar) in 541 aa overlap (33-572:1-541)
10 20 30 40 50 60
pF1KE2 LENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQPI
.:.::::::::.:: ...::: :::..:::
XP_006 MLQFPHISQCEELRLSLERDYHSLCERQPI
10 20 30
70 80 90 100 110 120
pF1KE2 GRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQVG
::::::.:: ::: : . :::.:::::::::.: :... ..:. .: .: .:
XP_006 GRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVP
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 QDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQPVT
..::.. ..: : :::.::. .. .:::: :: .::::..:.::::::::::::::
XP_006 RQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQPVT
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 KNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVN
:::::::::::::::::::::::::::::::::.::::::::::::.:::::::::::::
XP_006 KNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVN
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 SQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLEDL
:.:::.::::::::::::::::.:::::::::::.::. :: : ::.:::::: ::::::
XP_006 SRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE2 HRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQRY
::: ::::::::::::::.::::::::::::..:::. :.:::::::::::::..:.::
XP_006 HRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERY
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE2 GLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSICKM
.:::.:.::::.:::: :::::. ::.:.:::::.: : :. : ::..:: .:.:.:..
XP_006 TFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQ
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE2 LLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDIEQ
:: :: .::::. .: :::.::.:...::::: ::::.::: :::.:.::::::::::
XP_006 LLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQ
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE2 FSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLN-RNH
:::::::.:. ::.:::.::.:::: :::::::.:::::.:::::: .:..::::. ...
XP_006 FSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQ
460 470 480 490 500 510
550 560 570 580 590
pF1KE2 PPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS
:: :::::::::::.::. .. . :.:
XP_006 PPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR
520 530 540 550
>>XP_006714921 (OMIM: 600869) PREDICTED: G protein-coupl (559 aa)
initn: 2583 init1: 2446 opt: 2555 Z-score: 1160.9 bits: 224.7 E(85289): 6.3e-58
Smith-Waterman score: 2555; 69.8% identity (87.8% similar) in 524 aa overlap (50-572:20-543)
20 30 40 50 60 70
pF1KE2 GGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQPIGRLLFRQFCETRPGLEC
.::: :::..:::::::::.:: ::: :
XP_006 MPHPCALGLWTQQLPSLPTERDYHSLCERQPIGRLLFREFCATRPELSR
10 20 30 40
80 90 100 110 120 130
pF1KE2 YIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQVGQDLVSQTEEKLLQKPCK
. :::.:::::::::.: :... ..:. .: .: .: ..::.. ..: : :::
XP_006 CVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCK
50 60 70 80 90 100
140 150 160 170 180 190
pF1KE2 ELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQPVTKNTFRQYRVLGKGGFGE
.::. .. .:::: :: .::::..:.:::::::::::::::::::::::::::::::
XP_006 DLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGE
110 120 130 140 150 160
200 210 220 230 240 250
pF1KE2 VCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSQFVVNLAYAYETKDAL
::::::::::::::::.::::::::::::.::::::::::::::.:::.:::::::::::
XP_006 VCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDAL
170 180 190 200 210 220
260 270 280 290 300 310
pF1KE2 CLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLEDLHRENTVYRDLKPENILL
:::::.:::::::::::.::. :: : ::.:::::: ::::::::: ::::::::::::
XP_006 CLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILL
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE2 DDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMI
::.::::::::::::..:::. :.:::::::::::::..:.:: .:::.:.::::.::::
XP_006 DDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMI
290 300 310 320 330 340
380 390 400 410 420 430
pF1KE2 EGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSICKMLLTKDAKQRLGCQEEGA
:::::. ::.:.:::::.: : :. : ::..:: .:.:.:..:: :: .::::. .:
XP_006 AGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSA
350 360 370 380 390 400
440 450 460 470 480 490
pF1KE2 AEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDIEQFSTVKGVNLDHTDDDFY
:::.::.:...::::: ::::.::: :::.:.:::::::::::::::::.:. ::.:::
XP_006 REVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVELEPTDQDFY
410 420 430 440 450 460
500 510 520 530 540 550
pF1KE2 SKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLN-RNHPPEPPKKGLLQRLFKRQ
.::.:::: :::::::.:::::.:::::: .:..::::. ...:: :::::::::::.::
XP_006 QKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFSRQ
470 480 490 500 510 520
560 570 580 590
pF1KE2 HQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS
. .. . :.:
XP_006 RIAVETAATARKSSPPASSPQPEAPTSSWR
530 540 550
>>NP_001004057 (OMIM: 137026) G protein-coupled receptor (532 aa)
initn: 2542 init1: 2047 opt: 2541 Z-score: 1154.9 bits: 223.5 E(85289): 1.4e-57
Smith-Waterman score: 2541; 70.3% identity (89.3% similar) in 515 aa overlap (1-514:1-515)
10 20 30 40 50 60
pF1KE2 MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ
:::::::::..:::::.:: ::..:.:::::::: .: .::: .::..:..:: ::::::
NP_001 MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ
:::: ::::::.:.: :. .:.:::.::::::. :: .. : :. .... : . . .
NP_001 PIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPE
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 VGQDLVSQTEEKLLQK-PCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQ
. :.:.. . : .. : :. : :.. .:.:::::::.:: .: .:..::::::::::
NP_001 IPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQ
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILE
::::::::.:::::::::::::::::::::::::::.:.::::::::::.::::::.:::
NP_001 PVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 KVNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGL
::.:.:::.:::::::::::::::::::::::::::::.:::::.:.::.:::::. :::
NP_001 KVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 EDLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNN
:::.:: :::::::::::::: :::::::::::..::::. .::::::::::::::.::
NP_001 EDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNN
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 QRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSI
..: .:::.:::::::::::.:.:::. ::::: ::::.:. . : ::.::::.::::
NP_001 EKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSI
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 CKMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLD
:.:::::. ..::::. :::: ::.:: :...::.::::.::.::: :::.:::::::::
NP_001 CRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLD
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 IEQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLNR
:::::.:::. :: .:.:::..:.:: ::::::::
NP_001 IEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEGCLTMVPSEKEVEPKQC
490 500 510 520 530
540 550 560 570 580 590
pF1KE2 NHPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS
>>NP_001004056 (OMIM: 137026) G protein-coupled receptor (546 aa)
initn: 2454 init1: 2125 opt: 2426 Z-score: 1104.0 bits: 214.2 E(85289): 9.3e-55
Smith-Waterman score: 2436; 64.6% identity (82.9% similar) in 560 aa overlap (1-557:1-528)
10 20 30 40 50 60
pF1KE2 MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ
:::::::::..:::::. ..:: ::::::
NP_001 MELENIVANSLLLKARQ--------------------------------EKDYSSLCDKQ
10 20
70 80 90 100 110 120
pF1KE2 PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ
:::: ::::::.:.: :. .:.:::.::::::. :: .. : :. .... : . . .
NP_001 PIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPE
30 40 50 60 70 80
130 140 150 160 170
pF1KE2 VGQDLVSQTEEKLLQK-PCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQ
. :.:.. . : .. : :. : :.. .:.:::::::.:: .: .:..::::::::::
NP_001 IPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQ
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE2 PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILE
::::::::.:::::::::::::::::::::::::::.:.::::::::::.::::::.:::
NP_001 PVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILE
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE2 KVNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGL
::.:.:::.:::::::::::::::::::::::::::::.:::::.:.::.:::::. :::
NP_001 KVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGL
210 220 230 240 250 260
300 310 320 330 340 350
pF1KE2 EDLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNN
:::.:: :::::::::::::: :::::::::::..::::. .::::::::::::::.::
NP_001 EDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNN
270 280 290 300 310 320
360 370 380 390 400 410
pF1KE2 QRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSI
..: .:::.:::::::::::.:.:::. ::::: ::::.:. . : ::.::::.::::
NP_001 EKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSI
330 340 350 360 370 380
420 430 440 450 460 470
pF1KE2 CKMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLD
:.:::::. ..::::. :::: ::.:: :...::.::::.::.::: :::.:::::::::
NP_001 CRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLD
390 400 410 420 430 440
480 490 500 510 520 530
pF1KE2 IEQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLNR
:::::.:::. :: .:.:::..:.:: :::::::::::. :::..: . .:: ::..
NP_001 IEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEMIESGCFKDINKSESEEALPLDLDK
450 460 470 480 490 500
540 550 560 570 580 590
pF1KE2 N-HPPEP-PKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS
: : : :..:.. :::.:
NP_001 NIHTPVSRPNRGFFYRLFRRGGCLTMVPSEKEVEPKQC
510 520 530 540
590 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:21:28 2016 done: Sun Nov 6 15:21:29 2016
Total Scan time: 8.750 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]