Result of FASTA (omim) for
pFN21AE1996
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1996, 575 aa
1>>>pF1KE1996 575 - 575 aa - 575 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.9694+/-0.000427; mu= -1.2408+/- 0.027
mean_var=271.4031+/-55.465, 0's: 0 Z-trim(120.5): 20 B-trim: 40 in 1/54
Lambda= 0.077851
statistics sampled from 35769 (35789) to 35769 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.747), E-opt: 0.2 (0.42), width: 16
Scan time: 11.830
The best scores are: opt bits E(85289)
NP_037371 (OMIM: 300339) serine/threonine-protein ( 575) 3956 457.8 4.5e-128
XP_011544479 (OMIM: 300339) PREDICTED: serine/thre ( 565) 3627 420.8 5.8e-117
XP_011543932 (OMIM: 300339) PREDICTED: serine/thre ( 565) 3627 420.8 5.8e-117
NP_871626 (OMIM: 604944) serine/threonine-protein ( 529) 1980 235.8 2.7e-61
NP_002709 (OMIM: 604944) serine/threonine-protein (1150) 1980 236.1 4.9e-61
XP_006713749 (OMIM: 604944) PREDICTED: serine/thre (1150) 1980 236.1 4.9e-61
XP_011511258 (OMIM: 604944) PREDICTED: serine/thre (1150) 1980 236.1 4.9e-61
NP_001177376 (OMIM: 604944) serine/threonine-prote ( 414) 1887 225.3 3.1e-58
XP_016862276 (OMIM: 604944) PREDICTED: serine/thre (1061) 1860 222.6 5.3e-57
NP_001292085 (OMIM: 615902) serine/threonine-prote ( 343) 402 58.4 4.3e-08
NP_001292084 (OMIM: 615902) serine/threonine-prote ( 343) 402 58.4 4.3e-08
XP_016876878 (OMIM: 615902) PREDICTED: serine/thre ( 401) 402 58.5 4.9e-08
XP_005267839 (OMIM: 615902) PREDICTED: serine/thre ( 453) 402 58.5 5.4e-08
NP_060387 (OMIM: 615902) serine/threonine-protein ( 453) 402 58.5 5.4e-08
>>NP_037371 (OMIM: 300339) serine/threonine-protein phos (575 aa)
initn: 3956 init1: 3956 opt: 3956 Z-score: 2420.4 bits: 457.8 E(85289): 4.5e-128
Smith-Waterman score: 3956; 99.7% identity (100.0% similar) in 575 aa overlap (1-575:1-575)
10 20 30 40 50 60
pF1KE1 MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPGAWPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPGAWPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 APLAAPRPSGLEPPGTPGPGPALPLGAASSPRNAPHVRGTRRSAGTRVVQTRKEEPLPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 APLAAPRPSGLEPPGTPGPGPALPLGAASSPRNAPHVRGTRRSAGTRVVQTRKEEPLPPA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TSQSIPTFYFPRGRPQDSVNVDAVISKIESTFTRFPHERATMDDMGLVAKACGCPLYWKG
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_037 TSQSIPTFYFPRGRPQDSVNVDAVISKIESTFARFPHERATMDDMGLVAKACGCPLYWKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQEDFVPFLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 PLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQEDFVPFLQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 VVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 EADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 TRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 TRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 CRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 CRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 EQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETVGEPWEDGFEAELSPVEQKLSA
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_037 EQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETAGEPWEDGFEAELSPVEQKLSA
490 500 510 520 530 540
550 560 570
pF1KE1 LRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL
:::::::::::::::::::::::::::::::::::
NP_037 LRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL
550 560 570
>>XP_011544479 (OMIM: 300339) PREDICTED: serine/threonin (565 aa)
initn: 3627 init1: 3627 opt: 3627 Z-score: 2220.8 bits: 420.8 E(85289): 5.8e-117
Smith-Waterman score: 3630; 93.2% identity (94.4% similar) in 575 aa overlap (1-575:1-561)
10 20 30 40 50 60
pF1KE1 MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPGAWPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPGAWPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 APLAAPRPSGLEPPGTPGPGPALPLGAASSPRNAPHVRGTRRSAGTRVVQTRKEEPLPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APLAAPRPSGLEPPGTPGPGPALPLGAASSPRNAPHVRGTRRSAGTRVVQTRKEEPLPPA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TSQSIPTFYFPRGRPQDSVNVDAVISKIESTFTRFPHERATMDDMGLVAKACGCPLYWKG
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_011 TSQSIPTFYFPRGRPQDSVNVDAVISKIESTFARFPHERATMDDMGLVAKACGCPLYWKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQEDFVPFLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQEDFVPFLQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 TRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 CRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 EQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETVGEPWEDGFEAELSPVEQKLSA
::::::::::::::::::::::::::::::::::::::.::::::: .:: :
XP_011 EQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETAGEPWEDG--DGVSPCCPGWSW
490 500 510 520 530
550 560 570
pF1KE1 LRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL
. : .:. :: .: : :::
XP_011 M-------PELEGSPRLGPPTCRNYRC-----EPLPSLE
540 550 560
>>XP_011543932 (OMIM: 300339) PREDICTED: serine/threonin (565 aa)
initn: 3627 init1: 3627 opt: 3627 Z-score: 2220.8 bits: 420.8 E(85289): 5.8e-117
Smith-Waterman score: 3630; 93.2% identity (94.4% similar) in 575 aa overlap (1-575:1-561)
10 20 30 40 50 60
pF1KE1 MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPGAWPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPGAWPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 APLAAPRPSGLEPPGTPGPGPALPLGAASSPRNAPHVRGTRRSAGTRVVQTRKEEPLPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APLAAPRPSGLEPPGTPGPGPALPLGAASSPRNAPHVRGTRRSAGTRVVQTRKEEPLPPA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TSQSIPTFYFPRGRPQDSVNVDAVISKIESTFTRFPHERATMDDMGLVAKACGCPLYWKG
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_011 TSQSIPTFYFPRGRPQDSVNVDAVISKIESTFARFPHERATMDDMGLVAKACGCPLYWKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQEDFVPFLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQEDFVPFLQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 TRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 CRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 EQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETVGEPWEDGFEAELSPVEQKLSA
::::::::::::::::::::::::::::::::::::::.::::::: .:: :
XP_011 EQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETAGEPWEDG--DGVSPCCPGWSW
490 500 510 520 530
550 560 570
pF1KE1 LRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL
. : .:. :: .: : :::
XP_011 M-------PELEGSPRLGPPTCRNYRC-----EPLPSLE
540 550 560
>>NP_871626 (OMIM: 604944) serine/threonine-protein phos (529 aa)
initn: 2028 init1: 1980 opt: 1980 Z-score: 1221.4 bits: 235.8 E(85289): 2.7e-61
Smith-Waterman score: 2011; 62.4% identity (84.9% similar) in 458 aa overlap (74-528:53-491)
50 60 70 80 90 100
pF1KE1 RDQPTPGDGEQPGAWPTAPLAAPRPSGLEPPGTPGPGPALPLGAASSPRN---APHVRGT
:::: : :: . :::: .::: .
NP_871 RGCDFVLPSRFKKRLKSFQQTQIQNKPEKKPGTPLPPPAT---SPSSPRPLSPVPHVNN-
30 40 50 60 70
110 120 130 140 150 160
pF1KE1 RRSAGTRVVQTRKEEPLPPATSQSIPTFYFPRGRPQDSVNVDAVISKIESTFTRFPHERA
::.. :: : .:: ::::.: :. : . ..:.::..: . ...:
NP_871 -------VVNA----PL----SINIPRFYFPEGLPDTCSNHEQTLSRIETAFMDIEEQKA
80 90 100 110 120
170 180 190 200 210 220
pF1KE1 TMDDMGLVAKACGCPLYWKGPLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHL
. .:: .::.::::::::.:.: .::::.:: :....:.:::::.:.: ::::.::. :
NP_871 DIYEMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICL
130 140 150 160 170 180
230 240 250 260 270 280
pF1KE1 LMSPGCNYLVQEDFVPFLQDVVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGR
: .:.:. : ::::.:.:::::.:::::.:::.: ::::::::::::::::.:::::::.
NP_871 LAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGK
190 200 210 220 230 240
290 300 310 320 330 340
pF1KE1 ITCAELRRSSFLQNVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLA
:: .:.:.:.:::..:::::: ::::.:..:::::::::::::::::::::: :. ::.
NP_871 ITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLS
250 260 270 280 290 300
350 360 370 380 390 400
pF1KE1 RHNDHALSTKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCM
:.::.: :...:.::::::::::. .::::..:::::::::::::::..:::::::::::
NP_871 RYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCM
310 320 330 340 350 360
410 420 430 440 450 460
pF1KE1 DLDGDGALSMFELEYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKR
:.::::.:::.::::::::::.:...:.:: :::.: :::::::::: ..:::::.::::
NP_871 DVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKR
370 380 390 400 410 420
470 480 490 500 510 520
pF1KE1 CKLANVFFDTFFNIEKYLDHEQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETVG
:..:..:.:::::.::::::::.. ... .: .. ::: :::...:::::. :::::..
NP_871 CRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQ
430 440 450 460 470 480
530 540 550 560 570
pF1KE1 EPWEDGFEAELSPVEQKLSALRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL
...:::
NP_871 AQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEKCGKLQSVDEE
490 500 510 520
>>NP_002709 (OMIM: 604944) serine/threonine-protein phos (1150 aa)
initn: 2028 init1: 1980 opt: 1980 Z-score: 1216.7 bits: 236.1 E(85289): 4.9e-61
Smith-Waterman score: 2014; 58.2% identity (80.6% similar) in 505 aa overlap (27-528:632-1112)
10 20 30 40 50
pF1KE1 MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPG
:.: :. : . ..: . .:
NP_002 AQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT-
610 620 630 640 650 660
60 70 80 90 100 110
pF1KE1 AWPTAPLAAPRPSGLEPPGTPGPGPALPLGAASSPRN---APHVRGTRRSAGTRVVQTRK
: . .: . :::: : :: . :::: .::: . ::..
NP_002 --PEVIKIQNKPE--KKPGTPLPPPAT---SPSSPRPLSPVPHVNN--------VVNA--
670 680 690 700
120 130 140 150 160 170
pF1KE1 EEPLPPATSQSIPTFYFPRGRPQDSVNVDAVISKIESTFTRFPHERATMDDMGLVAKACG
:: : .:: ::::.: :. : . ..:.::..: . ...: . .:: .::.::
NP_002 --PL----SINIPRFYFPEGLPDTCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCG
710 720 730 740 750
180 190 200 210 220 230
pF1KE1 CPLYWKGPLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQED
::::::.:.: .::::.:: :....:.:::::.:.: ::::.::. :: .:.:. : :::
NP_002 CPLYWKAPMFRAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQED
760 770 780 790 800 810
240 250 260 270 280 290
pF1KE1 FVPFLQDVVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQ
:.:.:::::.:::::.:::.: ::::::::::::::::.:::::::.:: .:.:.:.:::
NP_002 FIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQ
820 830 840 850 860 870
300 310 320 330 340 350
pF1KE1 NVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMID
..:::::: ::::.:..:::::::::::::::::::::: :. ::.:.::.: :...:.
NP_002 TLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIE
880 890 900 910 920 930
360 370 380 390 400 410
pF1KE1 RIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFEL
::::::::::. .::::..:::::::::::::::..::::::::::::.::::.:::.::
NP_002 RIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYEL
940 950 960 970 980 990
420 430 440 450 460 470
pF1KE1 EYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFN
::::::::.:...:.:: :::.: :::::::::: ..:::::.:::::..:..:.:::::
NP_002 EYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFN
1000 1010 1020 1030 1040 1050
480 490 500 510 520 530
pF1KE1 IEKYLDHEQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETVGEPWEDGFEAELSP
.::::::::.. ... .: .. ::: :::...:::::. :::::.. ...:::
NP_002 LEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETD
1060 1070 1080 1090 1100 1110
540 550 560 570
pF1KE1 VEQKLSALRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL
NP_002 EPASPSEFGNKSNKILSASLPEKCGKLQSVDEE
1120 1130 1140 1150
>>XP_006713749 (OMIM: 604944) PREDICTED: serine/threonin (1150 aa)
initn: 2028 init1: 1980 opt: 1980 Z-score: 1216.7 bits: 236.1 E(85289): 4.9e-61
Smith-Waterman score: 2014; 58.2% identity (80.6% similar) in 505 aa overlap (27-528:632-1112)
10 20 30 40 50
pF1KE1 MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPG
:.: :. : . ..: . .:
XP_006 AQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT-
610 620 630 640 650 660
60 70 80 90 100 110
pF1KE1 AWPTAPLAAPRPSGLEPPGTPGPGPALPLGAASSPRN---APHVRGTRRSAGTRVVQTRK
: . .: . :::: : :: . :::: .::: . ::..
XP_006 --PEVIKIQNKPE--KKPGTPLPPPAT---SPSSPRPLSPVPHVNN--------VVNA--
670 680 690 700
120 130 140 150 160 170
pF1KE1 EEPLPPATSQSIPTFYFPRGRPQDSVNVDAVISKIESTFTRFPHERATMDDMGLVAKACG
:: : .:: ::::.: :. : . ..:.::..: . ...: . .:: .::.::
XP_006 --PL----SINIPRFYFPEGLPDTCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCG
710 720 730 740 750
180 190 200 210 220 230
pF1KE1 CPLYWKGPLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQED
::::::.:.: .::::.:: :....:.:::::.:.: ::::.::. :: .:.:. : :::
XP_006 CPLYWKAPMFRAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQED
760 770 780 790 800 810
240 250 260 270 280 290
pF1KE1 FVPFLQDVVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQ
:.:.:::::.:::::.:::.: ::::::::::::::::.:::::::.:: .:.:.:.:::
XP_006 FIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQ
820 830 840 850 860 870
300 310 320 330 340 350
pF1KE1 NVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMID
..:::::: ::::.:..:::::::::::::::::::::: :. ::.:.::.: :...:.
XP_006 TLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIE
880 890 900 910 920 930
360 370 380 390 400 410
pF1KE1 RIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFEL
::::::::::. .::::..:::::::::::::::..::::::::::::.::::.:::.::
XP_006 RIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYEL
940 950 960 970 980 990
420 430 440 450 460 470
pF1KE1 EYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFN
::::::::.:...:.:: :::.: :::::::::: ..:::::.:::::..:..:.:::::
XP_006 EYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFN
1000 1010 1020 1030 1040 1050
480 490 500 510 520 530
pF1KE1 IEKYLDHEQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETVGEPWEDGFEAELSP
.::::::::.. ... .: .. ::: :::...:::::. :::::.. ...:::
XP_006 LEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETD
1060 1070 1080 1090 1100 1110
540 550 560 570
pF1KE1 VEQKLSALRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL
XP_006 EPASPSEFGNKSNKILSASLPEKCGKLQSVDEE
1120 1130 1140 1150
>>XP_011511258 (OMIM: 604944) PREDICTED: serine/threonin (1150 aa)
initn: 2028 init1: 1980 opt: 1980 Z-score: 1216.7 bits: 236.1 E(85289): 4.9e-61
Smith-Waterman score: 2014; 58.2% identity (80.6% similar) in 505 aa overlap (27-528:632-1112)
10 20 30 40 50
pF1KE1 MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPG
:.: :. : . ..: . .:
XP_011 AQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT-
610 620 630 640 650 660
60 70 80 90 100 110
pF1KE1 AWPTAPLAAPRPSGLEPPGTPGPGPALPLGAASSPRN---APHVRGTRRSAGTRVVQTRK
: . .: . :::: : :: . :::: .::: . ::..
XP_011 --PEVIKIQNKPE--KKPGTPLPPPAT---SPSSPRPLSPVPHVNN--------VVNA--
670 680 690 700
120 130 140 150 160 170
pF1KE1 EEPLPPATSQSIPTFYFPRGRPQDSVNVDAVISKIESTFTRFPHERATMDDMGLVAKACG
:: : .:: ::::.: :. : . ..:.::..: . ...: . .:: .::.::
XP_011 --PL----SINIPRFYFPEGLPDTCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCG
710 720 730 740 750
180 190 200 210 220 230
pF1KE1 CPLYWKGPLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQED
::::::.:.: .::::.:: :....:.:::::.:.: ::::.::. :: .:.:. : :::
XP_011 CPLYWKAPMFRAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQED
760 770 780 790 800 810
240 250 260 270 280 290
pF1KE1 FVPFLQDVVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQ
:.:.:::::.:::::.:::.: ::::::::::::::::.:::::::.:: .:.:.:.:::
XP_011 FIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQ
820 830 840 850 860 870
300 310 320 330 340 350
pF1KE1 NVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMID
..:::::: ::::.:..:::::::::::::::::::::: :. ::.:.::.: :...:.
XP_011 TLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIE
880 890 900 910 920 930
360 370 380 390 400 410
pF1KE1 RIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFEL
::::::::::. .::::..:::::::::::::::..::::::::::::.::::.:::.::
XP_011 RIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYEL
940 950 960 970 980 990
420 430 440 450 460 470
pF1KE1 EYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFN
::::::::.:...:.:: :::.: :::::::::: ..:::::.:::::..:..:.:::::
XP_011 EYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFN
1000 1010 1020 1030 1040 1050
480 490 500 510 520 530
pF1KE1 IEKYLDHEQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETVGEPWEDGFEAELSP
.::::::::.. ... .: .. ::: :::...:::::. :::::.. ...:::
XP_011 LEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETD
1060 1070 1080 1090 1100 1110
540 550 560 570
pF1KE1 VEQKLSALRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL
XP_011 EPASPSEFGNKSNKILSASLPEKCGKLQSVDEE
1120 1130 1140 1150
>>NP_001177376 (OMIM: 604944) serine/threonine-protein p (414 aa)
initn: 1887 init1: 1887 opt: 1887 Z-score: 1166.5 bits: 225.3 E(85289): 3.1e-58
Smith-Waterman score: 1887; 68.5% identity (91.9% similar) in 371 aa overlap (158-528:6-376)
130 140 150 160 170 180
pF1KE1 FYFPRGRPQDSVNVDAVISKIESTFTRFPHERATMDDMGLVAKACGCPLYWKGPLFYGAG
..: . .:: .::.::::::::.:.: .::
NP_001 MDIEEQKADIYEMGKIAKVCGCPLYWKAPMFRAAG
10 20 30
190 200 210 220 230 240
pF1KE1 GERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQEDFVPFLQDVVNTHPG
::.:: :....:.:::::.:.: ::::.::. :: .:.:. : ::::.:.:::::.::::
NP_001 GEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPG
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE1 LSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEEEADINQL
:.:::.: ::::::::::::::::.:::::::.:: .:.:.:.:::..:::::: ::::.
NP_001 LTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQI
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE1 TEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAVTRGRKVQ
:..:::::::::::::::::::::: :. ::.:.::.: :...:.::::::::::. .:
NP_001 TDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQ
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE1 KEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQCRRLDSM
:::..:::::::::::::::..::::::::::::.::::.:::.::::::::::.:...:
NP_001 KEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAM
220 230 240 250 260 270
430 440 450 460 470 480
pF1KE1 AIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLDHEQKEQIS
.:: :::.: :::::::::: ..:::::.:::::..:..:.:::::.::::::::.. ..
NP_001 GIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFA
280 290 300 310 320 330
490 500 510 520 530 540
pF1KE1 LLRDGDSGGPELSDWEKYAAEEYDILVAEETVGEPWEDGFEAELSPVEQKLSALRSPLAQ
. .: .. ::: :::...:::::. :::::.. ...:::
NP_001 VQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNK
340 350 360 370 380 390
550 560 570
pF1KE1 RPFFEAPSPLGAVDLYEYACGDEDLEPL
NP_001 ILSASLPEKCGKLQSVDEE
400 410
>>XP_016862276 (OMIM: 604944) PREDICTED: serine/threonin (1061 aa)
initn: 1860 init1: 1860 opt: 1860 Z-score: 1144.4 bits: 222.6 E(85289): 5.3e-57
Smith-Waterman score: 1860; 69.5% identity (92.2% similar) in 361 aa overlap (168-528:663-1023)
140 150 160 170 180 190
pF1KE1 SVNVDAVISKIESTFTRFPHERATMDDMGLVAKACGCPLYWKGPLFYGAGGERTGSVSVH
: :.::::::::.:.: .::::.:: :...
XP_016 SQANLSVCRSPVGDKAKDTTSAVLIQQTPEVIKVCGCPLYWKAPMFRAAGGEKTGFVTAQ
640 650 660 670 680 690
200 210 220 230 240 250
pF1KE1 KFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQEDFVPFLQDVVNTHPGLSFLKEASEF
.:.:::::.:.: ::::.::. :: .:.:. : ::::.:.:::::.:::::.:::.: ::
XP_016 SFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPEF
700 710 720 730 740 750
260 270 280 290 300 310
pF1KE1 HSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEEEADINQLTEFFSYEHFY
::::::::::::::.:::::::.:: .:.:.:.:::..:::::: ::::.:..:::::::
XP_016 HSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHFY
760 770 780 790 800 810
320 330 340 350 360 370
pF1KE1 VIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAVTRGRKVQKEGKISYADF
::::::::::::::: :. ::.:.::.: :...:.::::::::::. .::::..:::::
XP_016 VIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYADF
820 830 840 850 860 870
380 390 400 410 420 430
pF1KE1 VWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQCRRLDSMAIEALPFQDC
::::::::::..::::::::::::.::::.:::.::::::::::.:...:.:: :::.:
XP_016 VWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDL
880 890 900 910 920 930
440 450 460 470 480 490
pF1KE1 LCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLDHEQKEQISLLRDGDSGGP
:::::::::: ..:::::.:::::..:..:.:::::.::::::::.. ... .: .. ::
XP_016 LCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDGP
940 950 960 970 980 990
500 510 520 530 540 550
pF1KE1 ELSDWEKYAAEEYDILVAEETVGEPWEDGFEAELSPVEQKLSALRSPLAQRPFFEAPSPL
: :::...:::::. :::::.. ...:::
XP_016 EPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEKC
1000 1010 1020 1030 1040 1050
560 570
pF1KE1 GAVDLYEYACGDEDLEPL
XP_016 GKLQSVDEE
1060
>>NP_001292085 (OMIM: 615902) serine/threonine-protein p (343 aa)
initn: 284 init1: 186 opt: 402 Z-score: 266.2 bits: 58.4 E(85289): 4.3e-08
Smith-Waterman score: 405; 24.3% identity (62.3% similar) in 313 aa overlap (192-501:43-342)
170 180 190 200 210 220
pF1KE1 MDDMGLVAKACGCPLYWKGPLFYGAGGERTGSVSVHKFVA-MWRKILQNCHDDAAKFVHL
: .:. .: . ::. :. . :
NP_001 FLKVGEKAGAKCKQFFTAKVFAKLLHTDSYGRISIMQFFNYVMRKVWL--HQTRIGL-SL
20 30 40 50 60
230 240 250 260 270 280
pF1KE1 LMSPGCNYLVQEDFVPFLQDVVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGR
: .:: . :. .. ... : : :. :... :.: :. :.....:. .. .:.
NP_001 YDVAGQGYLRESDLENYILELIPTLPQLDGLEKS--FYSFYVCTAVRKFFFFLDPLRTGK
70 80 90 100 110 120
290 300 310 320 330
pF1KE1 ITCAELRRSSFLQNVALL--EEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADD
: .. :::... : :: . .: :..:: .: .. .:: ::. ... ..
NP_001 IKIQDILACSFLDDLLELRDEELSKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEE
130 140 150 160 170 180
340 350 360 370 380 390
pF1KE1 LARHNDHALSTKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFR
:.:.. .... ..::.:. .: .:...: .. :... :..: :....: :.
NP_001 LSRYGTATMTNVFLDRVFQECLTY------DGEMDYKTYLDFVLALENRKEPAALQYIFK
190 200 210 220 230 240
400 410 420 430 440 450
pF1KE1 CMDLDGDGALSMFELEYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDL
.:... : :..: :.::.. . . . . . ::: ...:.:::. ::.::::
NP_001 LLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDL
250 260 270 280 290 300
460 470 480 490 500 510
pF1KE1 KRCKLANVFFDTFFNIEKYLDHEQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEET
. ... ..... . .:..: .:. . . .. .:.:
NP_001 INSNQGDTVTTILIDLNGFWTYENRE--ALVANDSENSADLDDT
310 320 330 340
520 530 540 550 560 570
pF1KE1 VGEPWEDGFEAELSPVEQKLSALRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL
575 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:53:46 2016 done: Sun Nov 6 12:53:47 2016
Total Scan time: 11.830 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]