Result of FASTA (omim) for
pFN21AE1973
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1973, 541 aa
1>>>pF1KE1973 541 - 541 aa - 541 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8697+/-0.000521; mu= 21.2354+/- 0.032
mean_var=76.5267+/-15.153, 0's: 0 Z-trim(108.1): 156 B-trim: 0 in 0/49
Lambda= 0.146611
statistics sampled from 16005 (16184) to 16005 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.533), E-opt: 0.2 (0.19), width: 16
Scan time: 6.980
The best scores are: opt bits E(85289)
NP_003846 (OMIM: 604494) interleukin-18 receptor 1 ( 541) 3587 769.1 0
XP_005264096 (OMIM: 604494) PREDICTED: interleukin ( 540) 3570 765.5 0
XP_016860670 (OMIM: 604494) PREDICTED: interleukin ( 386) 2529 545.2 1.3e-154
NP_001269328 (OMIM: 604494) interleukin-18 recepto ( 385) 2512 541.6 1.6e-153
XP_005264097 (OMIM: 604494) PREDICTED: interleukin ( 488) 2472 533.2 6.8e-151
XP_011510401 (OMIM: 604494) PREDICTED: interleukin ( 487) 2125 459.8 8.4e-129
XP_016860671 (OMIM: 604494) PREDICTED: interleukin ( 292) 1905 413.1 6e-115
XP_016860672 (OMIM: 604494) PREDICTED: interleukin ( 291) 1888 409.5 7.2e-114
XP_016860673 (OMIM: 604494) PREDICTED: interleukin ( 291) 1888 409.5 7.2e-114
XP_011529207 (OMIM: 300277) PREDICTED: X-linked in ( 562) 655 149.0 3.7e-35
XP_016884892 (OMIM: 300277) PREDICTED: X-linked in ( 686) 655 149.1 4.3e-35
NP_059112 (OMIM: 300277) X-linked interleukin-1 re ( 686) 655 149.1 4.3e-35
XP_016884730 (OMIM: 300143,300206) PREDICTED: inte ( 570) 625 142.6 3e-33
XP_016884729 (OMIM: 300143,300206) PREDICTED: inte ( 696) 625 142.7 3.5e-33
NP_055086 (OMIM: 300143,300206) interleukin-1 rece ( 696) 625 142.7 3.5e-33
NP_001307912 (OMIM: 147810) interleukin-1 receptor ( 425) 597 136.6 1.5e-31
XP_011509418 (OMIM: 147810) PREDICTED: interleukin ( 569) 597 136.7 1.8e-31
XP_011509419 (OMIM: 147810) PREDICTED: interleukin ( 569) 597 136.7 1.8e-31
XP_005263987 (OMIM: 147810) PREDICTED: interleukin ( 569) 597 136.7 1.8e-31
XP_011509417 (OMIM: 147810) PREDICTED: interleukin ( 569) 597 136.7 1.8e-31
XP_005263991 (OMIM: 147810) PREDICTED: interleukin ( 569) 597 136.7 1.8e-31
XP_011509420 (OMIM: 147810) PREDICTED: interleukin ( 569) 597 136.7 1.8e-31
NP_001307910 (OMIM: 147810) interleukin-1 receptor ( 569) 597 136.7 1.8e-31
NP_000868 (OMIM: 147810) interleukin-1 receptor ty ( 569) 597 136.7 1.8e-31
XP_016859478 (OMIM: 147810) PREDICTED: interleukin ( 569) 597 136.7 1.8e-31
NP_001307911 (OMIM: 147810) interleukin-1 receptor ( 569) 597 136.7 1.8e-31
NP_001307909 (OMIM: 147810) interleukin-1 receptor ( 569) 597 136.7 1.8e-31
NP_001307907 (OMIM: 147810) interleukin-1 receptor ( 569) 597 136.7 1.8e-31
NP_001161401 (OMIM: 602626) interleukin-1 receptor ( 570) 578 132.7 3e-30
NP_001161400 (OMIM: 602626) interleukin-1 receptor ( 570) 578 132.7 3e-30
NP_002173 (OMIM: 602626) interleukin-1 receptor ac ( 570) 578 132.7 3e-30
XP_011510389 (OMIM: 604509) PREDICTED: interleukin ( 457) 561 129.0 3.1e-29
XP_011510390 (OMIM: 604509) PREDICTED: interleukin ( 457) 561 129.0 3.1e-29
NP_003844 (OMIM: 604509) interleukin-18 receptor a ( 599) 561 129.1 3.7e-29
NP_001307913 (OMIM: 147810) interleukin-1 receptor ( 386) 558 128.3 4.2e-29
NP_001161403 (OMIM: 602626) interleukin-1 receptor ( 687) 544 125.6 5e-28
XP_016861837 (OMIM: 602626) PREDICTED: interleukin ( 376) 540 124.5 5.8e-28
NP_003845 (OMIM: 604512) interleukin-1 receptor-li ( 575) 542 125.1 5.9e-28
XP_005264093 (OMIM: 604512) PREDICTED: interleukin ( 575) 542 125.1 5.9e-28
XP_011510396 (OMIM: 604512) PREDICTED: interleukin ( 595) 542 125.1 6e-28
XP_005264092 (OMIM: 604512) PREDICTED: interleukin ( 603) 542 125.1 6.1e-28
XP_016860663 (OMIM: 604512) PREDICTED: interleukin ( 606) 542 125.1 6.1e-28
XP_011510394 (OMIM: 604512) PREDICTED: interleukin ( 617) 542 125.1 6.2e-28
XP_011510393 (OMIM: 604512) PREDICTED: interleukin ( 622) 535 123.6 1.7e-27
XP_016860667 (OMIM: 604512) PREDICTED: interleukin ( 424) 532 122.8 2.1e-27
XP_016860668 (OMIM: 604512) PREDICTED: interleukin ( 424) 532 122.8 2.1e-27
XP_006712885 (OMIM: 604512) PREDICTED: interleukin ( 444) 532 122.9 2.1e-27
XP_006712883 (OMIM: 604512) PREDICTED: interleukin ( 529) 526 121.7 5.8e-27
XP_016860666 (OMIM: 604512) PREDICTED: interleukin ( 443) 525 121.4 5.9e-27
XP_016860664 (OMIM: 604512) PREDICTED: interleukin ( 508) 519 120.2 1.6e-26
>>NP_003846 (OMIM: 604494) interleukin-18 receptor 1 iso (541 aa)
initn: 3587 init1: 3587 opt: 3587 Z-score: 4104.0 bits: 769.1 E(85289): 0
Smith-Waterman score: 3587; 100.0% identity (100.0% similar) in 541 aa overlap (1-541:1-541)
10 20 30 40 50 60
pF1KE1 MNCRELPLTLWVLISVSTAESCTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MNCRELPLTLWVLISVSTAESCTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 HLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 PGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 DFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSE
490 500 510 520 530 540
pF1KE1 S
:
NP_003 S
>>XP_005264096 (OMIM: 604494) PREDICTED: interleukin-18 (540 aa)
initn: 2125 init1: 2125 opt: 3570 Z-score: 4084.6 bits: 765.5 E(85289): 0
Smith-Waterman score: 3570; 99.8% identity (99.8% similar) in 541 aa overlap (1-541:1-540)
10 20 30 40 50 60
pF1KE1 MNCRELPLTLWVLISVSTAESCTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNCRELPLTLWVLISVSTAESCTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYR
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_005 ASTGGTDTKSFILVRK-DMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYR
310 320 330 340 350
370 380 390 400 410 420
pF1KE1 HLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVV
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE1 PGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVT
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE1 DFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSE
480 490 500 510 520 530
pF1KE1 S
:
XP_005 S
540
>>XP_016860670 (OMIM: 604494) PREDICTED: interleukin-18 (386 aa)
initn: 2529 init1: 2529 opt: 2529 Z-score: 2896.5 bits: 545.2 E(85289): 1.3e-154
Smith-Waterman score: 2529; 100.0% identity (100.0% similar) in 385 aa overlap (157-541:2-386)
130 140 150 160 170 180
pF1KE1 SKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQGYYSCV
::::::::::::::::::::::::::::::
XP_016 MNCKKLLLENNKNPTIKKNAEFEDQGYYSCV
10 20 30
190 200 210 220 230 240
pF1KE1 HFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSALLNEEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSALLNEEDV
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE1 IYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTVASTGGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTVASTGGT
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE1 DTKSFILVRKADMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYRHLTRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTKSFILVRKADMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYRHLTRRD
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE1 ETLTDGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETLTDGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVV
220 230 240 250 260 270
430 440 450 460 470 480
pF1KE1 DEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVTDFTFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVTDFTFLP
280 290 300 310 320 330
490 500 510 520 530 540
pF1KE1 QSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSES
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSES
340 350 360 370 380
>>NP_001269328 (OMIM: 604494) interleukin-18 receptor 1 (385 aa)
initn: 1459 init1: 1459 opt: 2512 Z-score: 2877.1 bits: 541.6 E(85289): 1.6e-153
Smith-Waterman score: 2512; 99.7% identity (99.7% similar) in 385 aa overlap (157-541:2-385)
130 140 150 160 170 180
pF1KE1 SKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQGYYSCV
::::::::::::::::::::::::::::::
NP_001 MNCKKLLLENNKNPTIKKNAEFEDQGYYSCV
10 20 30
190 200 210 220 230 240
pF1KE1 HFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSALLNEEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSALLNEEDV
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE1 IYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTVASTGGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTVASTGGT
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE1 DTKSFILVRKADMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYRHLTRRD
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTKSFILVRK-DMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYRHLTRRD
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE1 ETLTDGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETLTDGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVV
220 230 240 250 260 270
430 440 450 460 470 480
pF1KE1 DEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVTDFTFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVTDFTFLP
280 290 300 310 320 330
490 500 510 520 530 540
pF1KE1 QSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSES
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSES
340 350 360 370 380
>>XP_005264097 (OMIM: 604494) PREDICTED: interleukin-18 (488 aa)
initn: 3203 init1: 2471 opt: 2472 Z-score: 2830.0 bits: 533.2 E(85289): 6.8e-151
Smith-Waterman score: 3101; 90.2% identity (90.2% similar) in 541 aa overlap (1-541:1-488)
10 20 30 40 50 60
pF1KE1 MNCRELPLTLWVLISVSTAESCTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNCRELPLTLWVLISVSTAESCTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 HLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVV
::::::::::
XP_005 HLTRRDETLT--------------------------------------------------
370
430 440 450 460 470 480
pF1KE1 PGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ---AVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVT
380 390 400 410 420
490 500 510 520 530 540
pF1KE1 DFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSE
430 440 450 460 470 480
pF1KE1 S
:
XP_005 S
>>XP_011510401 (OMIM: 604494) PREDICTED: interleukin-18 (487 aa)
initn: 3227 init1: 2125 opt: 2125 Z-score: 2433.4 bits: 459.8 E(85289): 8.4e-129
Smith-Waterman score: 3123; 90.0% identity (90.0% similar) in 541 aa overlap (1-541:1-487)
10 20 30 40 50 60
pF1KE1 MNCRELPLTLWVLISVSTAESCTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNCRELPLTLWVLISVSTAESCTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYR
::::::::::::::::
XP_011 ASTGGTDTKSFILVRK--------------------------------------------
310
370 380 390 400 410 420
pF1KE1 HLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVV
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ----------DGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVV
320 330 340 350 360
430 440 450 460 470 480
pF1KE1 PGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVT
370 380 390 400 410 420
490 500 510 520 530 540
pF1KE1 DFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSE
430 440 450 460 470 480
pF1KE1 S
:
XP_011 S
>>XP_016860671 (OMIM: 604494) PREDICTED: interleukin-18 (292 aa)
initn: 1905 init1: 1905 opt: 1905 Z-score: 2184.7 bits: 413.1 E(85289): 6e-115
Smith-Waterman score: 1905; 100.0% identity (100.0% similar) in 292 aa overlap (250-541:1-292)
220 230 240 250 260 270
pF1KE1 PKLNHVAVELGKNVRLNCSALLNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHAS
::::::::::::::::::::::::::::::
XP_016 MFGEENGSDPNIHEEKEMRIMTPEGKWHAS
10 20 30
280 290 300 310 320 330
pF1KE1 KVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILV
40 50 60 70 80 90
340 350 360 370 380 390
pF1KE1 AVVCLVTVCVIYRVDLVLFYRHLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVVCLVTVCVIYRVDLVLFYRHLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEI
100 110 120 130 140 150
400 410 420 430 440 450
pF1KE1 LPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESG
160 170 180 190 200 210
460 470 480 490 500 510
pF1KE1 LHEALVERKIKIILIEFTPVTDFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHEALVERKIKIILIEFTPVTDFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYL
220 230 240 250 260 270
520 530 540
pF1KE1 MPAKTVKPGRDEPEVLPVLSES
::::::::::::::::::::::
XP_016 MPAKTVKPGRDEPEVLPVLSES
280 290
>>XP_016860672 (OMIM: 604494) PREDICTED: interleukin-18 (291 aa)
initn: 1459 init1: 1459 opt: 1888 Z-score: 2165.3 bits: 409.5 E(85289): 7.2e-114
Smith-Waterman score: 1888; 99.7% identity (99.7% similar) in 292 aa overlap (250-541:1-291)
220 230 240 250 260 270
pF1KE1 PKLNHVAVELGKNVRLNCSALLNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHAS
::::::::::::::::::::::::::::::
XP_016 MFGEENGSDPNIHEEKEMRIMTPEGKWHAS
10 20 30
280 290 300 310 320 330
pF1KE1 KVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILV
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_016 KVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRK-DMADIPGHVFTRGMIIAVLILV
40 50 60 70 80
340 350 360 370 380 390
pF1KE1 AVVCLVTVCVIYRVDLVLFYRHLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVVCLVTVCVIYRVDLVLFYRHLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEI
90 100 110 120 130 140
400 410 420 430 440 450
pF1KE1 LPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESG
150 160 170 180 190 200
460 470 480 490 500 510
pF1KE1 LHEALVERKIKIILIEFTPVTDFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHEALVERKIKIILIEFTPVTDFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYL
210 220 230 240 250 260
520 530 540
pF1KE1 MPAKTVKPGRDEPEVLPVLSES
::::::::::::::::::::::
XP_016 MPAKTVKPGRDEPEVLPVLSES
270 280 290
>>XP_016860673 (OMIM: 604494) PREDICTED: interleukin-18 (291 aa)
initn: 1459 init1: 1459 opt: 1888 Z-score: 2165.3 bits: 409.5 E(85289): 7.2e-114
Smith-Waterman score: 1888; 99.7% identity (99.7% similar) in 292 aa overlap (250-541:1-291)
220 230 240 250 260 270
pF1KE1 PKLNHVAVELGKNVRLNCSALLNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHAS
::::::::::::::::::::::::::::::
XP_016 MFGEENGSDPNIHEEKEMRIMTPEGKWHAS
10 20 30
280 290 300 310 320 330
pF1KE1 KVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILV
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_016 KVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRK-DMADIPGHVFTRGMIIAVLILV
40 50 60 70 80
340 350 360 370 380 390
pF1KE1 AVVCLVTVCVIYRVDLVLFYRHLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVVCLVTVCVIYRVDLVLFYRHLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEI
90 100 110 120 130 140
400 410 420 430 440 450
pF1KE1 LPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESG
150 160 170 180 190 200
460 470 480 490 500 510
pF1KE1 LHEALVERKIKIILIEFTPVTDFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHEALVERKIKIILIEFTPVTDFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYL
210 220 230 240 250 260
520 530 540
pF1KE1 MPAKTVKPGRDEPEVLPVLSES
::::::::::::::::::::::
XP_016 MPAKTVKPGRDEPEVLPVLSES
270 280 290
>>XP_011529207 (OMIM: 300277) PREDICTED: X-linked interl (562 aa)
initn: 555 init1: 223 opt: 655 Z-score: 752.2 bits: 149.0 E(85289): 3.7e-35
Smith-Waterman score: 668; 33.4% identity (61.9% similar) in 446 aa overlap (109-523:7-435)
80 90 100 110 120 130
pF1KE1 HDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCFTERQVTSKIVEVKKFFQI
:.: . .. :.. : . :: : .:
XP_011 MKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEI
10 20 30
140 150 160 170 180 190
pF1KE1 TCEN--SYYQTLVNSTSL-YKNCK----KLLLENNKNPTIKKNAEFEDQGYYSCVHFLHH
.: . .. .. . . ::.:: . .. .. : . .... :: : :.: :..
XP_011 SCPDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCE--LKY
40 50 60 70 80 90
200 210 220 230 240
pF1KE1 NGKLFNITKTFNIT-IVEDRSNIVPVLLGPKLNH---VAVELGKNVRLNCSALLNEED--
.::: : ...: .. :. : : : :. . :.::: . . :.:...
XP_011 EGKLVRRTTELKVTALLTDKP---PKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGES
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE1 --VIYWMFGEENGSDPNIH-EEKEMRIMTPE-GKWHASKVLRIENIGESNLNVLYNCTVA
.:::: ::. . : .: :.:.. . :. .. .: .... :..: . :.: :
XP_011 GPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELALIFDSVVEADL-ANYTCHVE
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE1 STGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYRH
. .: : .:.:: :. .. : . :...:.... .. : : ..:.::::.
XP_011 NRNGRKHAS-VLLRKKDLIY---KIELAGGLGAIFLLLVLLVVIYKC--YNIELMLFYRQ
220 230 240 250 260
370 380 390 400 410
pF1KE1 LTRRDETLTDGKTYDAFVSYLK------ECRPENGEEHTFAVEILPRVLEKHFGYKLCIF
::: :.: :::..:: : .: .: ::. ::.:.:: :::::.:::: :
XP_011 HFGADETNDDNKEYDAYLSYTKVDQDTLDC--DNPEEEQFALEVLPDVLEKHYGYKLFIP
270 280 290 300 310 320
420 430 440 450 460 470
pF1KE1 ERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMSNE--VRYELESGLHEALVERKIKIIL
:::..:.:. .... .:.::::::::. .:. . .:::: ::. :: .::.::
XP_011 ERDLIPSGTYMEDLTRYVEQSRRLIIVLTPDYILRRGWSIFELESRLHNMLVSGEIKVIL
330 340 350 360 370 380
480 490 500 510 520
pF1KE1 IEFTPVT------DFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKP
:: : . . : .:.:::. ..:::..:: . ::.:::.:.: :: :
XP_011 IECTELKGKVNCQEVESLKRSIKLLS---LIKWKGSKSSKLNSKFWKHLVYEMPIKKKEM
390 400 410 420 430
530 540
pF1KE1 GRDEPEVLPVLSES
XP_011 LPRCHVLDSAEQGLFGELQPIPSIAMTSTSATLVSSQADLPEFHPSDSMQIRHCCRGYKH
440 450 460 470 480 490
541 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:22:42 2016 done: Sun Nov 6 18:22:43 2016
Total Scan time: 6.980 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]