Result of FASTA (omim) for
pFN21AE1958
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1958, 514 aa
1>>>pF1KE1958 514 - 514 aa - 514 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2859+/-0.000349; mu= 18.8053+/- 0.022
mean_var=78.6225+/-16.060, 0's: 0 Z-trim(115.2): 20 B-trim: 27 in 1/54
Lambda= 0.144644
statistics sampled from 25458 (25477) to 25458 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.299), width: 16
Scan time: 8.990
The best scores are: opt bits E(85289)
NP_005856 (OMIM: 607169) thymus-specific serine pr ( 514) 3439 727.4 2.4e-209
XP_016865651 (OMIM: 607169) PREDICTED: thymus-spec ( 454) 2564 544.8 2e-154
XP_016865650 (OMIM: 607169) PREDICTED: thymus-spec ( 488) 1927 411.9 2.2e-114
XP_016865653 (OMIM: 607169) PREDICTED: thymus-spec ( 357) 1605 344.6 2.9e-94
XP_016865652 (OMIM: 607169) PREDICTED: thymus-spec ( 417) 1605 344.6 3.3e-94
XP_016865654 (OMIM: 607169) PREDICTED: thymus-spec ( 257) 1210 262.0 1.5e-69
NP_037511 (OMIM: 610537) dipeptidyl peptidase 2 pr ( 492) 624 140.0 1.6e-32
XP_011516901 (OMIM: 610537) PREDICTED: dipeptidyl ( 514) 566 127.9 7.2e-29
XP_011516902 (OMIM: 610537) PREDICTED: dipeptidyl ( 484) 557 126.0 2.5e-28
XP_016870141 (OMIM: 610537) PREDICTED: dipeptidyl ( 436) 491 112.2 3.2e-24
XP_016870140 (OMIM: 610537) PREDICTED: dipeptidyl ( 458) 433 100.1 1.5e-20
NP_005031 (OMIM: 176785) lysosomal Pro-X carboxype ( 496) 410 95.3 4.4e-19
NP_955450 (OMIM: 176785) lysosomal Pro-X carboxype ( 517) 391 91.4 7.1e-18
XP_005274150 (OMIM: 176785) PREDICTED: lysosomal P ( 391) 302 72.7 2.2e-12
NP_001306143 (OMIM: 176785) lysosomal Pro-X carbox ( 391) 302 72.7 2.2e-12
XP_006717146 (OMIM: 610537) PREDICTED: dipeptidyl ( 509) 254 62.8 2.8e-09
XP_005266132 (OMIM: 610537) PREDICTED: dipeptidyl ( 565) 254 62.8 3.1e-09
>>NP_005856 (OMIM: 607169) thymus-specific serine protea (514 aa)
initn: 3439 init1: 3439 opt: 3439 Z-score: 3879.5 bits: 727.4 E(85289): 2.4e-209
Smith-Waterman score: 3439; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514)
10 20 30 40 50 60
pF1KE1 MAVWLAQWLGPLLLVSLWGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAVWLAQWLGPLLLVSLWGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 WLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AWGALVISLEHRFYGLSIPAGGLEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AWGALVISLEHRFYGLSIPAGGLEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 CFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLEC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RAAVSVAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELLGALQALVGGVVQYDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RAAVSVAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELLGALQALVGGVVQYDG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QTGAPLSVRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLGQKCLSFSRAETVAQLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QTGAPLSVRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLGQKCLSFSRAETVAQLRS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 TEPQLSGVGDRQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLDLCEQVFGLSALSVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TEPQLSGVGDRQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLDLCEQVFGLSALSVAQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 AVAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AVAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPER
430 440 450 460 470 480
490 500 510
pF1KE1 PSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
::::::::::::::::::::::::::::::::::
NP_005 PSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
490 500 510
>>XP_016865651 (OMIM: 607169) PREDICTED: thymus-specific (454 aa)
initn: 2584 init1: 2561 opt: 2564 Z-score: 2893.4 bits: 544.8 E(85289): 2e-154
Smith-Waterman score: 2896; 88.1% identity (88.3% similar) in 514 aa overlap (1-514:1-454)
10 20 30 40 50 60
pF1KE1 MAVWLAQWLGPLLLVSLWGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAVWLAQWLGPLLLVSLWGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 WLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AWGALVISLEHRFYGLSIPAGGLEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWGALVISLEHRFYGLSIPAGGLEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 CFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLEC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RAAVSVAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELLGALQALVGGVVQYDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAAVSVAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELLGALQALVGGVVQYDG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QTGAPLSVRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLGQKCLSFSRAETVAQLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTGAPLSVRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLGQKCLSFSRAETVAQLRS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 TEPQLSGVGDRQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLDLCEQVFGLSALSVAQ
:::::::::::::::::::::::.
XP_016 TEPQLSGVGDRQWLYQTCTEFGFW------------------------------------
370 380
430 440 450 460 470 480
pF1KE1 AVAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPER
::::::::::::::::::::::::::::::::::::
XP_016 ------------------------DTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPER
390 400 410 420
490 500 510
pF1KE1 PSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
::::::::::::::::::::::::::::::::::
XP_016 PSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
430 440 450
>>XP_016865650 (OMIM: 607169) PREDICTED: thymus-specific (488 aa)
initn: 3257 init1: 1927 opt: 1927 Z-score: 2174.6 bits: 411.9 E(85289): 2.2e-114
Smith-Waterman score: 3209; 94.9% identity (94.9% similar) in 514 aa overlap (1-514:1-488)
10 20 30 40 50 60
pF1KE1 MAVWLAQWLGPLLLVSLWGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAVWLAQWLGPLLLVSLWGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 WLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AWGALVISLEHRFYGLSIPAGGLEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWGALVISLEHRFYGLSIPAGGLEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 CFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLEC
::::::::::::::::: :::::::::::::::::
XP_016 CFGGSYAGSLAAWARLK--------------------------VVSRSLMSTAIGGSLEC
190 200 210
250 260 270 280 290 300
pF1KE1 RAAVSVAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELLGALQALVGGVVQYDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAAVSVAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELLGALQALVGGVVQYDG
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 QTGAPLSVRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLGQKCLSFSRAETVAQLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTGAPLSVRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLGQKCLSFSRAETVAQLRS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 TEPQLSGVGDRQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLDLCEQVFGLSALSVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEPQLSGVGDRQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLDLCEQVFGLSALSVAQ
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 AVAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPER
400 410 420 430 440 450
490 500 510
pF1KE1 PSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
::::::::::::::::::::::::::::::::::
XP_016 PSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
460 470 480
>>XP_016865653 (OMIM: 607169) PREDICTED: thymus-specific (357 aa)
initn: 2055 init1: 1603 opt: 1605 Z-score: 1813.3 bits: 344.6 E(85289): 2.9e-94
Smith-Waterman score: 2055; 69.3% identity (69.5% similar) in 514 aa overlap (1-514:1-357)
10 20 30 40 50 60
pF1KE1 MAVWLAQWLGPLLLVSLWGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAVWLAQWLGPLLLVSLWGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 WLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AWGALVISLEHRFYGLSIPAGGLEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWGALVISLEHRFYGLSIPAGGLEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 CFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLEC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLE-
190 200 210 220 230
250 260 270 280 290 300
pF1KE1 RAAVSVAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELLGALQALVGGVVQYDG
XP_016 ------------------------------------------------------------
310 320 330 340 350 360
pF1KE1 QTGAPLSVRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLGQKCLSFSRAETVAQLRS
::::::::::::::::::::::::
XP_016 ------------------------------------IVLHSLGQKCLSFSRAETVAQLRS
240 250 260
370 380 390 400 410 420
pF1KE1 TEPQLSGVGDRQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLDLCEQVFGLSALSVAQ
:::::::::::::::::::::::.
XP_016 TEPQLSGVGDRQWLYQTCTEFGFW------------------------------------
270 280
430 440 450 460 470 480
pF1KE1 AVAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPER
::::::::::::::::::::::::::::::::::::
XP_016 ------------------------DTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPER
290 300 310 320
490 500 510
pF1KE1 PSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
::::::::::::::::::::::::::::::::::
XP_016 PSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
330 340 350
>>XP_016865652 (OMIM: 607169) PREDICTED: thymus-specific (417 aa)
initn: 1603 init1: 1603 opt: 1605 Z-score: 1812.3 bits: 344.6 E(85289): 3.3e-94
Smith-Waterman score: 2598; 81.1% identity (81.1% similar) in 514 aa overlap (1-514:1-417)
10 20 30 40 50 60
pF1KE1 MAVWLAQWLGPLLLVSLWGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAVWLAQWLGPLLLVSLWGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 WLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AWGALVISLEHRFYGLSIPAGGLEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWGALVISLEHRFYGLSIPAGGLEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 CFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLEC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLE-
190 200 210 220 230
250 260 270 280 290 300
pF1KE1 RAAVSVAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELLGALQALVGGVVQYDG
XP_016 ------------------------------------------------------------
310 320 330 340 350 360
pF1KE1 QTGAPLSVRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLGQKCLSFSRAETVAQLRS
::::::::::::::::::::::::
XP_016 ------------------------------------IVLHSLGQKCLSFSRAETVAQLRS
240 250 260
370 380 390 400 410 420
pF1KE1 TEPQLSGVGDRQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLDLCEQVFGLSALSVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEPQLSGVGDRQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLDLCEQVFGLSALSVAQ
270 280 290 300 310 320
430 440 450 460 470 480
pF1KE1 AVAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPER
330 340 350 360 370 380
490 500 510
pF1KE1 PSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
::::::::::::::::::::::::::::::::::
XP_016 PSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
390 400 410
>>XP_016865654 (OMIM: 607169) PREDICTED: thymus-specific (257 aa)
initn: 1210 init1: 1210 opt: 1210 Z-score: 1369.8 bits: 262.0 E(85289): 1.5e-69
Smith-Waterman score: 1210; 98.4% identity (98.9% similar) in 183 aa overlap (332-514:75-257)
310 320 330 340 350 360
pF1KE1 TGAPLSVRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLGQKCLSFSRAETVAQLRST
: .::::::::::::::::::::::::::
XP_016 LGLSLGPGAAALPKVGWLEQLLDPFNVSDRRSFLQIVLHSLGQKCLSFSRAETVAQLRST
50 60 70 80 90 100
370 380 390 400 410 420
pF1KE1 EPQLSGVGDRQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLDLCEQVFGLSALSVAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPQLSGVGDRQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLDLCEQVFGLSALSVAQA
110 120 130 140 150 160
430 440 450 460 470 480
pF1KE1 VAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPERP
170 180 190 200 210 220
490 500 510
pF1KE1 SDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
:::::::::::::::::::::::::::::::::
XP_016 SDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
230 240 250
>--
initn: 502 init1: 502 opt: 502 Z-score: 571.3 bits: 114.3 E(85289): 4.4e-25
Smith-Waterman score: 502; 100.0% identity (100.0% similar) in 74 aa overlap (1-74:1-74)
10 20 30 40 50 60
pF1KE1 MAVWLAQWLGPLLLVSLWGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAVWLAQWLGPLLLVSLWGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 WLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAP
::::::::::::::
XP_016 WLEQLLDPFNVSDRRSFLQIVLHSLGQKCLSFSRAETVAQLRSTEPQLSGVGDRQWLYQT
70 80 90 100 110 120
>>NP_037511 (OMIM: 610537) dipeptidyl peptidase 2 prepro (492 aa)
initn: 499 init1: 184 opt: 624 Z-score: 705.0 bits: 140.0 E(85289): 1.6e-32
Smith-Waterman score: 624; 30.5% identity (57.3% similar) in 485 aa overlap (45-509:14-480)
20 30 40 50 60
pF1KE1 VSLWGLLAPASLLRRLGEHIQQFQESSAQGLGL-SLGPGAAALPKVGWLE----QLLDPF
::: .: :: : :. : : :: :
NP_037 MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHF
10 20 30 40
70 80 90 100 110 120
pF1KE1 NVS--DRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAPAWGALVI
: ..: ::. :.:. :: .::::.. :.::.. . . : :: :::..
NP_037 NFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 SLEHRFYGLSIPAGG--LEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWICFGGS
:::.:: :.: :. . .. ..:. . :::: . :: : .. ....: : ::::
NP_037 FAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLG-AQDAPAIAFGGS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 YAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLECRAAVS
:.: :.:. :.:.:::. ...:.:::: :: ... :. :.. . : : .: .:
NP_037 YGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFF-RDVTADFEGQSPKCTQGVR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 VAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELL----GALQALVGGVVQYDGQ
:: ... . .: : ..: :...: ::. .. ..:. .:. .:. : .
NP_037 EAFRQIKDLFLQG--AYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTD
230 240 250 260 270
310 320 330 340 350
pF1KE1 TGAPLS---VRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLG-QKCLSFSRAETVAQ
.:: :. : :: :.. ::: . .: .. : ..: .. :
NP_037 FLGPLPANPVKVGCDRLL------SEAQRITGLRALAGLVYNASGSEHCYDIYR----LY
280 290 300 310 320
360 370 380 390 400 410
pF1KE1 LRSTEPQLSGVGD--RQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLDLCEQVFGLSA
..: :.: : : ::.:::... . .: : .:: : .: . :..
NP_037 HSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFT----DELRQRYCLDT
330 340 350 360 370 380
420 430 440 450 460 470
pF1KE1 LSV-AQAVAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCL
.: . .:..::. .:....: ::. ::: .. . :..: .. :. :.: :
NP_037 WGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHL
390 400 410 420 430 440
480 490 500 510
pF1KE1 DMAPERPSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
:. .: : :. .:. . :.: :.. :
NP_037 DLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL
450 460 470 480 490
>>XP_011516901 (OMIM: 610537) PREDICTED: dipeptidyl pept (514 aa)
initn: 460 init1: 145 opt: 566 Z-score: 639.3 bits: 127.9 E(85289): 7.2e-29
Smith-Waterman score: 566; 29.5% identity (55.7% similar) in 526 aa overlap (6-509:4-502)
10 20 30 40 50
pF1KE1 MAVWLAQWLGPLLLVSLWGL--LAPASLLRRLGEH-------IQQFQESSAQGLGLSLGP
: : .:.::..: :: : .. :: : .. . : :: : : :
XP_011 MGSAPW-APVLLLAL-GLRGLQAGGEWRRPPAHSPVPAPPLRFASPHSPQGPGPRL-P
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 GAAALPKVGWLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVM
:: :: .. :: . :.. : . :: .::::.. :.::.. .
XP_011 GAL-LPAASGPLQLR-----ALRQQDLPSALPGVGFWVRGEGPIFFYTGNEGDVWAFANN
60 70 80 90 100
120 130 140 150 160
pF1KE1 RGHPAALAPAWGALVISLEHRFYGLSIPAGG--LEMAQLRFLSSRLALADVVSARLALSR
. : :: :::.. :::.:: :.: :. . .. ..:. . :::: . :: :
XP_011 SAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRR
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE1 LFNISSSSPWICFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSL
.. ....: : :::::.: :.:. :.:.:::. ...:.:::: :: ... :. :..
XP_011 DLG-AQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFF-RDV
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 MSTAIGGSLECRAAVSVAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELL----
. : : .: .: :: ... . .: : ..: :...: ::. .. ..:.
XP_011 TADFEGQSPKCTQGVREAFRQIKDLFLQG--AYDTVRWEFGTCQPLSDEKDLTQLFMFAR
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE1 GALQALVGGVVQYDGQTGAPLS---VRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSL
.:. .:. : . .:: :. : :: :.. ::: . .: ..
XP_011 NAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLL------SEAQRITGLRALAGLVYNAS
290 300 310 320 330
350 360 370 380 390
pF1KE1 G-QKCLSFSRAETVAQLRSTEPQLSGVGD--RQWLYQTCTEFGFYVTCENPRCPFSQLPA
: ..: .. : ..: :.: : : ::.:::... . .: : .::
XP_011 GSEHCYDIYRLYH----SCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPF
340 350 360 370 380 390
400 410 420 430 440 450
pF1KE1 LPSQLDLCEQVFGLSALSV-AQAVAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQAL
: .: . :.. .: . .:..::. .:....: ::. ::: .. . :
XP_011 T----DELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNL
400 410 420 430 440 450
460 470 480 490 500 510
pF1KE1 GSSESTLLIRTGSHCLDMAPERPSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
..: .. :. :.: ::. .: : :. .:. . :.: :.. :
XP_011 SASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPR
460 470 480 490 500 510
XP_011 LSL
>>XP_011516902 (OMIM: 610537) PREDICTED: dipeptidyl pept (484 aa)
initn: 460 init1: 145 opt: 557 Z-score: 629.5 bits: 126.0 E(85289): 2.5e-28
Smith-Waterman score: 557; 29.7% identity (57.9% similar) in 435 aa overlap (88-509:56-472)
60 70 80 90 100 110
pF1KE1 KVGWLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAA
:: .::::.. :.::.. . . :
XP_011 GALLPAASGPLQLRALRQQDLPSALPGVGFWVRGEGPIFFYTGNEGDVWAFANNSAFVAE
30 40 50 60 70 80
120 130 140 150 160 170
pF1KE1 LAPAWGALVISLEHRFYGLSIPAGG--LEMAQLRFLSSRLALADVVSARLALSRLFNISS
:: :::.. :::.:: :.: :. . .. ..:. . :::: . :: : .. ..
XP_011 LAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLG-AQ
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE1 SSPWICFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIG
..: : :::::.: :.:. :.:.:::. ...:.:::: :: ... :. :.. . :
XP_011 DAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFF-RDVTADFEG
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE1 GSLECRAAVSVAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELL----GALQAL
: .: .: :: ... . .: : ..: :...: ::. .. ..:. .:. .:
XP_011 QSPKCTQGVREAFRQIKDLFLQG--AYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVL
210 220 230 240 250 260
300 310 320 330 340
pF1KE1 VGGVVQYDGQTGAPLS---VRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLG-QKCL
. : . .:: :. : :: :.. ::: . .: .. : ..:
XP_011 AMMDYPYPTDFLGPLPANPVKVGCDRLL------SEAQRITGLRALAGLVYNASGSEHCY
270 280 290 300 310
350 360 370 380 390 400
pF1KE1 SFSRAETVAQLRSTEPQLSGVGD--RQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLD
.. : ..: :.: : : ::.:::... . .: : .:: :
XP_011 DIYRL----YHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPF----TD
320 330 340 350 360
410 420 430 440 450 460
pF1KE1 LCEQVFGLSALSV-AQAVAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSEST
.: . :.. .: . .:..::. .:....: ::. ::: .. . :..: .
XP_011 ELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIA
370 380 390 400 410 420
470 480 490 500 510
pF1KE1 LLIRTGSHCLDMAPERPSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV
. :. :.: ::. .: : :. .:. . :.: :.. :
XP_011 VTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL
430 440 450 460 470 480
>>XP_016870141 (OMIM: 610537) PREDICTED: dipeptidyl pept (436 aa)
initn: 372 init1: 184 opt: 491 Z-score: 555.7 bits: 112.2 E(85289): 3.2e-24
Smith-Waterman score: 491; 31.9% identity (57.6% similar) in 373 aa overlap (45-398:14-372)
20 30 40 50 60
pF1KE1 VSLWGLLAPASLLRRLGEHIQQFQESSAQGLGL-SLGPGAAALPKVGWLE----QLLDPF
::: .: :: : :. : : :: :
XP_016 MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHF
10 20 30 40
70 80 90 100 110 120
pF1KE1 NVS--DRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAPAWGALVI
: ..: ::. :.:. :: .::::.. :.::.. . . : :: :::..
XP_016 NFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 SLEHRFYGLSIPAGG--LEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWICFGGS
:::.:: :.: :. . .. ..:. . :::: . :: : .. ....: : ::::
XP_016 FAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLG-AQDAPAIAFGGS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 YAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLECRAAVS
:.: :.:. :.:.:::. ...:.:::: :: ... :. :.. . : : .: .:
XP_016 YGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFF-RDVTADFEGQSPKCTQGVR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 VAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELL----GALQALVGGVVQYDGQ
:: ... . .: : ..: :...: ::. .. ..:. .:. .:. : .
XP_016 EAFRQIKDLFLQG--AYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTD
230 240 250 260 270
310 320 330 340 350
pF1KE1 TGAPLS---VRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLG-QKCLSFSRAETVAQ
.:: :. : :: :.. ::: . .: .. : ..: .. :
XP_016 FLGPLPANPVKVGCDRLL------SEAQRITGLRALAGLVYNASGSEHCYDIYRLYH---
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE1 LRSTEPQLSGVGD--RQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLDLCEQVFGLSA
..: :.: : : ::.:::... . .: : .::
XP_016 -SCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRSQSRQQHHL
340 350 360 370 380
420 430 440 450 460 470
pF1KE1 LSVAQAVAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLD
XP_016 LQREPGPLGRGRDSEEPECLSHRRHHPGGSAPPRPQSLPPRRSCFRG
390 400 410 420 430
514 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:19:31 2016 done: Sun Nov 6 21:19:33 2016
Total Scan time: 8.990 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]