Result of FASTA (omim) for
pFN21AE1944
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1944, 500 aa
1>>>pF1KE1944 500 - 500 aa - 500 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.4917+/-0.000432; mu= -9.2562+/- 0.027
mean_var=412.7631+/-82.689, 0's: 0 Z-trim(123.1): 32 B-trim: 667 in 1/54
Lambda= 0.063128
statistics sampled from 42377 (42431) to 42377 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.497), width: 16
Scan time: 12.100
The best scores are: opt bits E(85289)
NP_004547 (OMIM: 604548) NF-kappa-B inhibitor epsi ( 500) 3408 324.5 4.4e-88
XP_011525499 (OMIM: 109560) PREDICTED: B-cell lymp ( 539) 651 73.4 1.8e-12
XP_011525500 (OMIM: 109560) PREDICTED: B-cell lymp ( 696) 651 73.5 2.2e-12
NP_005169 (OMIM: 109560) B-cell lymphoma 3 protein ( 454) 592 68.0 6.6e-11
XP_016882599 (OMIM: 109560) PREDICTED: B-cell lymp ( 356) 582 67.0 1e-10
XP_016882598 (OMIM: 109560) PREDICTED: B-cell lymp ( 434) 582 67.1 1.2e-10
XP_011525502 (OMIM: 109560) PREDICTED: B-cell lymp ( 378) 573 66.2 1.9e-10
NP_065390 (OMIM: 164008,612132) NF-kappa-B inhibit ( 317) 483 57.9 5e-08
XP_011538132 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 460 56.2 4e-07
XP_011538133 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 460 56.2 4e-07
NP_001309864 (OMIM: 164012,615577) nuclear factor ( 858) 460 56.2 4.4e-07
NP_002493 (OMIM: 164012,615577) nuclear factor NF- ( 899) 460 56.2 4.5e-07
NP_001248332 (OMIM: 164012,615577) nuclear factor ( 899) 460 56.2 4.5e-07
NP_001275653 (OMIM: 164012,615577) nuclear factor ( 899) 460 56.2 4.5e-07
NP_001309863 (OMIM: 164012,615577) nuclear factor ( 900) 460 56.2 4.5e-07
NP_001070962 (OMIM: 164012,615577) nuclear factor ( 900) 460 56.2 4.5e-07
XP_016871767 (OMIM: 164012,615577) PREDICTED: nucl (1081) 460 56.3 5.2e-07
XP_011530310 (OMIM: 164011,616576) PREDICTED: nucl ( 916) 452 55.5 7.6e-07
NP_001158884 (OMIM: 164011,616576) nuclear factor ( 968) 452 55.5 7.9e-07
NP_001306155 (OMIM: 164011,616576) nuclear factor ( 968) 452 55.5 7.9e-07
NP_003989 (OMIM: 164011,616576) nuclear factor NF- ( 969) 452 55.5 7.9e-07
XP_011530308 (OMIM: 164011,616576) PREDICTED: nucl ( 976) 452 55.5 7.9e-07
NP_002494 (OMIM: 604495) NF-kappa-B inhibitor beta ( 356) 372 47.9 6e-05
>>NP_004547 (OMIM: 604548) NF-kappa-B inhibitor epsilon (500 aa)
initn: 3408 init1: 3408 opt: 3408 Z-score: 1702.3 bits: 324.5 E(85289): 4.4e-88
Smith-Waterman score: 3408; 100.0% identity (100.0% similar) in 500 aa overlap (1-500:1-500)
10 20 30 40 50 60
pF1KE1 MNQRRSESRPGNHRLQAYAEPGKGDSGGAGPLSGSARRGRGGGGAIRVRRPCWSGGAGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MNQRRSESRPGNHRLQAYAEPGKGDSGGAGPLSGSARRGRGGGGAIRVRRPCWSGGAGRG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GGPAWAVRLPTVTAGWTWPALRTLSSLRAGPSEPHSPGRRPPRAGRPLCQADPQPGKAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GGPAWAVRLPTVTAGWTWPALRTLSSLRAGPSEPHSPGRRPPRAGRPLCQADPQPGKAAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RSLEPDPAQTGPRPARAAGMSEARKGPDEAEESQYDSGIESLRSLRSLPESTSAPASGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RSLEPDPAQTGPRPARAAGMSEARKGPDEAEESQYDSGIESLRSLRSLPESTSAPASGPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 DGSPQPCTHPPGPVKEPQEKEDADGERADSTYGSSSLTYTLSLLGGPEAEDPAPRLPLPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DGSPQPCTHPPGPVKEPQEKEDADGERADSTYGSSSLTYTLSLLGGPEAEDPAPRLPLPH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VGALSPQQLEALTYISEDGDTLVHLAVIHEAPAVLLCCLALLPQEVLDIQNNLYQTALHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VGALSPQQLEALTYISEDGDTLVHLAVIHEAPAVLLCCLALLPQEVLDIQNNLYQTALHL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 AVHLDQPGAVRALVLKGASRALQDRHGDTALHVACQRQHLACARCLLEGRPEPGRGTSHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AVHLDQPGAVRALVLKGASRALQDRHGDTALHVACQRQHLACARCLLEGRPEPGRGTSHS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LDLQLQNWQGLACLHIATLQKNQPLMELLLRNGADIDVQEGTSGKTALHLAVETQERGLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LDLQLQNWQGLACLHIATLQKNQPLMELLLRNGADIDVQEGTSGKTALHLAVETQERGLV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 QFLLQAGAQVDARMLNGCTPLHLAAGRGLMGISSTLCKAGADSLLRNVEDETPQDLTEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QFLLQAGAQVDARMLNGCTPLHLAAGRGLMGISSTLCKAGADSLLRNVEDETPQDLTEES
430 440 450 460 470 480
490 500
pF1KE1 LVLLPFDDLKISGKLLLCTD
::::::::::::::::::::
NP_004 LVLLPFDDLKISGKLLLCTD
490 500
>>XP_011525499 (OMIM: 109560) PREDICTED: B-cell lymphoma (539 aa)
initn: 546 init1: 324 opt: 651 Z-score: 344.9 bits: 73.4 E(85289): 1.8e-12
Smith-Waterman score: 651; 35.7% identity (54.9% similar) in 448 aa overlap (53-473:9-430)
30 40 50 60 70
pF1KE1 KGDSGGAGPLSGSARRGRGGGGAIRVRRPCWSGGAGRGGGPAWAVRLPTVTA--G--WTW
:. : ::: :. :::... : .
XP_011 MRHVEWQRWKRG-GRGIVPG---RLPSASPCPGCVSSL
10 20 30
80 90 100 110 120 130
pF1KE1 PALRTLSSLRAGPSEPHSPGRRPPRAGRPLCQADPQPGKAARRSLEPDPAQTGPRPARAA
: : . :: : . : :. : : :..::. : : . :: : :
XP_011 PLRR--KRLREGKCLAKVTQRFSRLQGKSRRPAKP-PSRAAEPSRSPAAVPGGPMPRCPA
40 50 60 70 80 90
140 150 160 170 180
pF1KE1 GMSEARKGPDEAEESQYDSGIESL------RSLRSLPESTSAP--ASG---PSDGSPQPC
: . .:: . . .:. . : ::. .:: :.: : : :
XP_011 GAMD--EGPVDLRTRPKAAGLPGAALPLRKRPLRAPSPEPAAPRGAAGLVVPLDPLRGGC
100 110 120 130 140
190 200 210 220 230 240
pF1KE1 THP--PGPVKEPQEKEDADGERADSTYGSSSLT--YTLSLLGGPEAEDPAPRLPLPHVGA
: ::: :. : .. : ..: : .:.: : :: :
XP_011 DLPAVPGP---PH-----GLARPEALYYPGALLPLYPTRAMGSPF---PLVNLPTPLYPM
150 160 170 180 190
250 260 270 280 290
pF1KE1 LSPQQ------LEALTYISEDGDTLVHLAVIH-EAPAVL-LCCLALLPQEVLDIQNNLYQ
. :.. . : .::::: .:.::.. . ::: : : . ::: ::: :
XP_011 MCPMEHPLSADIAMATRADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQ
200 210 220 230 240 250
300 310 320 330 340 350
pF1KE1 TALHLAVHLDQPGAVRALVLKGASRALQDRHGDTALHVACQRQHLACARCLLEGRPEPGR
: ::::: :..:: :: ::: ::::.:: :.::... .: : ::.. ::
XP_011 TPLHLAVITTLPSVVRLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDS-AAPG-
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE1 GTSHSLDLQLQNWQGLACLHIATLQKNQPLMELLLRNGADIDVQEGTSGKTALHLAVETQ
.:::. .:..::. ::.:. . : ..:::. :::::. . ::.. : :::..
XP_011 ----TLDLEARNYDGLTALHVAVNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENN
320 330 340 350 360 370
420 430 440 450 460 470
pF1KE1 ERGLVQFLLQAGAQVDARMLNGCTPLHLAAGRGLMGISSTLCKAGADSLLRNVEDETPQD
..::.::: ::.:.:.: .: . :: :.::::. . :: ..:::: :.: ...::
XP_011 SLSMVQLLLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLM
380 390 400 410 420 430
480 490 500
pF1KE1 LTEESLVLLPFDDLKISGKLLLCTD
XP_011 VARSRRVIDILRGKATRPASTSQPDPSPDRSANTSPESSSRLSSNGLLSASPSSSPSQSP
440 450 460 470 480 490
>>XP_011525500 (OMIM: 109560) PREDICTED: B-cell lymphoma (696 aa)
initn: 513 init1: 324 opt: 651 Z-score: 343.4 bits: 73.5 E(85289): 2.2e-12
Smith-Waterman score: 651; 35.7% identity (54.9% similar) in 448 aa overlap (53-473:146-567)
30 40 50 60 70
pF1KE1 KGDSGGAGPLSGSARRGRGGGGAIRVRRPCWSGGAGRGGGPAWAVRLPTVTA--G--WTW
:. : ::: :. :::... : .
XP_011 RDTISGALPTLTPPPAPLDPQLMRHVEWQRWKRG-GRGIVPG---RLPSASPCPGCVSSL
120 130 140 150 160 170
80 90 100 110 120 130
pF1KE1 PALRTLSSLRAGPSEPHSPGRRPPRAGRPLCQADPQPGKAARRSLEPDPAQTGPRPARAA
: : . :: : . : :. : : :..::. : : . :: : :
XP_011 PLRR--KRLREGKCLAKVTQRFSRLQGKSRRPAKP-PSRAAEPSRSPAAVPGGPMPRCPA
180 190 200 210 220
140 150 160 170 180
pF1KE1 GMSEARKGPDEAEESQYDSGIESL------RSLRSLPESTSAP--ASG---PSDGSPQPC
: . .:: . . .:. . : ::. .:: :.: : : :
XP_011 GAMD--EGPVDLRTRPKAAGLPGAALPLRKRPLRAPSPEPAAPRGAAGLVVPLDPLRGGC
230 240 250 260 270 280
190 200 210 220 230 240
pF1KE1 THP--PGPVKEPQEKEDADGERADSTYGSSSLT--YTLSLLGGPEAEDPAPRLPLPHVGA
: ::: :. : .. : ..: : .:.: : :: :
XP_011 DLPAVPGP---PH-----GLARPEALYYPGALLPLYPTRAMGSPF---PLVNLPTPLYPM
290 300 310 320 330
250 260 270 280 290
pF1KE1 LSPQQ------LEALTYISEDGDTLVHLAVIH-EAPAVL-LCCLALLPQEVLDIQNNLYQ
. :.. . : .::::: .:.::.. . ::: : : . ::: ::: :
XP_011 MCPMEHPLSADIAMATRADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQ
340 350 360 370 380 390
300 310 320 330 340 350
pF1KE1 TALHLAVHLDQPGAVRALVLKGASRALQDRHGDTALHVACQRQHLACARCLLEGRPEPGR
: ::::: :..:: :: ::: ::::.:: :.::... .: : ::.. ::
XP_011 TPLHLAVITTLPSVVRLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDS-AAPG-
400 410 420 430 440 450
360 370 380 390 400 410
pF1KE1 GTSHSLDLQLQNWQGLACLHIATLQKNQPLMELLLRNGADIDVQEGTSGKTALHLAVETQ
.:::. .:..::. ::.:. . : ..:::. :::::. . ::.. : :::..
XP_011 ----TLDLEARNYDGLTALHVAVNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENN
460 470 480 490 500
420 430 440 450 460 470
pF1KE1 ERGLVQFLLQAGAQVDARMLNGCTPLHLAAGRGLMGISSTLCKAGADSLLRNVEDETPQD
..::.::: ::.:.:.: .: . :: :.::::. . :: ..:::: :.: ...::
XP_011 SLSMVQLLLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLM
510 520 530 540 550 560
480 490 500
pF1KE1 LTEESLVLLPFDDLKISGKLLLCTD
XP_011 VARSRRVSRGSCGHAPCTRVSAGWLQVIDILRGKATRPASTSQPDPSPDRSANTSPESSS
570 580 590 600 610 620
>>NP_005169 (OMIM: 109560) B-cell lymphoma 3 protein [Ho (454 aa)
initn: 513 init1: 324 opt: 592 Z-score: 316.8 bits: 68.0 E(85289): 6.6e-11
Smith-Waterman score: 592; 39.0% identity (59.1% similar) in 328 aa overlap (163-473:35-345)
140 150 160 170 180
pF1KE1 RPARAAGMSEARKGPDEAEESQYDSGIESLRSLRSLPESTSAP--ASG---PSDGSPQPC
: ::. .:: :.: : : :
NP_005 PAGAMDEGPVDLRTRPKAAGLPGAALPLRKRPLRAPSPEPAAPRGAAGLVVPLDPLRGGC
10 20 30 40 50 60
190 200 210 220 230 240
pF1KE1 THP--PGPVKEPQEKEDADGERADSTYGSSSLT--YTLSLLGGPEAEDPAPRLPLPHVGA
: ::: :. : .. : ..: : .:.: : :: :
NP_005 DLPAVPGP---PH-----GLARPEALYYPGALLPLYPTRAMGSPF---PLVNLPTPLYPM
70 80 90 100 110
250 260 270 280 290
pF1KE1 LSPQQ------LEALTYISEDGDTLVHLAVIH-EAPAVL-LCCLALLPQEVLDIQNNLYQ
. :.. . : .::::: .:.::.. . ::: : : . ::: ::: :
NP_005 MCPMEHPLSADIAMATRADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQ
120 130 140 150 160 170
300 310 320 330 340 350
pF1KE1 TALHLAVHLDQPGAVRALVLKGASRALQDRHGDTALHVACQRQHLACARCLLEGRPEPGR
: ::::: :..:: :: ::: ::::.:: :.::... .: : ::.. ::
NP_005 TPLHLAVITTLPSVVRLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDS-AAPG-
180 190 200 210 220 230
360 370 380 390 400 410
pF1KE1 GTSHSLDLQLQNWQGLACLHIATLQKNQPLMELLLRNGADIDVQEGTSGKTALHLAVETQ
.:::. .:..::. ::.:. . : ..:::. :::::. . ::.. : :::..
NP_005 ----TLDLEARNYDGLTALHVAVNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENN
240 250 260 270 280
420 430 440 450 460 470
pF1KE1 ERGLVQFLLQAGAQVDARMLNGCTPLHLAAGRGLMGISSTLCKAGADSLLRNVEDETPQD
..::.::: ::.:.:.: .: . :: :.::::. . :: ..:::: :.: ...::
NP_005 SLSMVQLLLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLM
290 300 310 320 330 340
480 490 500
pF1KE1 LTEESLVLLPFDDLKISGKLLLCTD
NP_005 VARSRRVIDILRGKATRPASTSQPDPSPDRSANTSPESSSRLSSNGLLSASPSSSPSQSP
350 360 370 380 390 400
>>XP_016882599 (OMIM: 109560) PREDICTED: B-cell lymphoma (356 aa)
initn: 513 init1: 324 opt: 582 Z-score: 313.2 bits: 67.0 E(85289): 1e-10
Smith-Waterman score: 582; 39.4% identity (61.6% similar) in 302 aa overlap (184-473:13-305)
160 170 180 190 200 210
pF1KE1 QYDSGIESLRSLRSLPESTSAPASGPSDGSPQPC-THPPGPVKEPQEKEDAD-GERADST
: : . : . : ..: :. :: .
XP_016 MEEGRERNRSWPPAECQSLPRVRLFTPTKEETAQRGEVFGQG
10 20 30 40
220 230 240 250 260
pF1KE1 YGSSSLT--YTLSLLGGPEAEDPAPRLPLPHVGALSPQQ------LEALTYISEDGDTLV
. . .: : .:.: : :: : . :.. . : .::::: .
XP_016 HPARALLPLYPTRAMGSPF---PLVNLPTPLYPMMCPMEHPLSADIAMATRADEDGDTPL
50 60 70 80 90
270 280 290 300 310 320
pF1KE1 HLAVIH-EAPAVL-LCCLALLPQEVLDIQNNLYQTALHLAVHLDQPGAVRALVLKGASRA
:.::.. . ::: : : . ::: ::: :: ::::: :..:: :: :::
XP_016 HIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLLVTAGASPM
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE1 LQDRHGDTALHVACQRQHLACARCLLEGRPEPGRGTSHSLDLQLQNWQGLACLHIATLQK
::::.:: :.::... .: : ::.. :: .:::. .:..::. ::.:. .
XP_016 ALDRHGQTAAHLACEHRSPTCLRALLDS-AAPG-----TLDLEARNYDGLTALHVAVNTE
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE1 NQPLMELLLRNGADIDVQEGTSGKTALHLAVETQERGLVQFLLQAGAQVDARMLNGCTPL
: ..:::. :::::. . ::.. : :::.. ..::.::: ::.:.:.: .: . :
XP_016 CQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQLLLQHGANVNAQMYSGSSAL
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE1 HLAAGRGLMGISSTLCKAGADSLLRNVEDETPQDLTEESLVLLPFDDLKISGKLLLCTD
: :.::::. . :: ..:::: :.: ...::
XP_016 HSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVARSRRVSRGSCGHAPCTRVSAGWLQ
280 290 300 310 320 330
XP_016 ASVPERRGVRVSVPLRGGEWVSL
340 350
>>XP_016882598 (OMIM: 109560) PREDICTED: B-cell lymphoma (434 aa)
initn: 513 init1: 324 opt: 582 Z-score: 312.1 bits: 67.1 E(85289): 1.2e-10
Smith-Waterman score: 582; 39.4% identity (61.6% similar) in 302 aa overlap (184-473:13-305)
160 170 180 190 200 210
pF1KE1 QYDSGIESLRSLRSLPESTSAPASGPSDGSPQPC-THPPGPVKEPQEKEDAD-GERADST
: : . : . : ..: :. :: .
XP_016 MEEGRERNRSWPPAECQSLPRVRLFTPTKEETAQRGEVFGQG
10 20 30 40
220 230 240 250 260
pF1KE1 YGSSSLT--YTLSLLGGPEAEDPAPRLPLPHVGALSPQQ------LEALTYISEDGDTLV
. . .: : .:.: : :: : . :.. . : .::::: .
XP_016 HPARALLPLYPTRAMGSPF---PLVNLPTPLYPMMCPMEHPLSADIAMATRADEDGDTPL
50 60 70 80 90
270 280 290 300 310 320
pF1KE1 HLAVIH-EAPAVL-LCCLALLPQEVLDIQNNLYQTALHLAVHLDQPGAVRALVLKGASRA
:.::.. . ::: : : . ::: ::: :: ::::: :..:: :: :::
XP_016 HIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLLVTAGASPM
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE1 LQDRHGDTALHVACQRQHLACARCLLEGRPEPGRGTSHSLDLQLQNWQGLACLHIATLQK
::::.:: :.::... .: : ::.. :: .:::. .:..::. ::.:. .
XP_016 ALDRHGQTAAHLACEHRSPTCLRALLDS-AAPG-----TLDLEARNYDGLTALHVAVNTE
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE1 NQPLMELLLRNGADIDVQEGTSGKTALHLAVETQERGLVQFLLQAGAQVDARMLNGCTPL
: ..:::. :::::. . ::.. : :::.. ..::.::: ::.:.:.: .: . :
XP_016 CQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQLLLQHGANVNAQMYSGSSAL
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE1 HLAAGRGLMGISSTLCKAGADSLLRNVEDETPQDLTEESLVLLPFDDLKISGKLLLCTD
: :.::::. . :: ..:::: :.: ...::
XP_016 HSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVARSRRVSRGSCGHAPCTRVSAGWLQ
280 290 300 310 320 330
XP_016 VIDILRGKATRPASTSQPDPSPDRSANTSPESSSRLSSNGLLSASPSSSPSQSPPRDPPG
340 350 360 370 380 390
>>XP_011525502 (OMIM: 109560) PREDICTED: B-cell lymphoma (378 aa)
initn: 513 init1: 324 opt: 573 Z-score: 308.5 bits: 66.2 E(85289): 1.9e-10
Smith-Waterman score: 573; 43.4% identity (66.5% similar) in 251 aa overlap (227-473:6-249)
200 210 220 230 240 250
pF1KE1 PQEKEDADGERADSTYGSSSLTYTLSLLGGPEAEDPAPRLPL--PHVGALSPQQLEALTY
: .. :.: :. : :: . . :
XP_011 MGSPFPLVNLPTPLYPMMCPMEHPLSAD-IAMATR
10 20 30
260 270 280 290 300 310
pF1KE1 ISEDGDTLVHLAVIH-EAPAVL-LCCLALLPQEVLDIQNNLYQTALHLAVHLDQPGAVRA
.::::: .:.::.. . ::: : : . ::: ::: :: ::::: :..::
XP_011 ADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRL
40 50 60 70 80 90
320 330 340 350 360 370
pF1KE1 LVLKGASRALQDRHGDTALHVACQRQHLACARCLLEGRPEPGRGTSHSLDLQLQNWQGLA
:: ::: ::::.:: :.::... .: : ::.. :: .:::. .:..::.
XP_011 LVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDS-AAPG-----TLDLEARNYDGLT
100 110 120 130 140
380 390 400 410 420 430
pF1KE1 CLHIATLQKNQPLMELLLRNGADIDVQEGTSGKTALHLAVETQERGLVQFLLQAGAQVDA
::.:. . : ..:::. :::::. . ::.. : :::.. ..::.::: ::.:.:
XP_011 ALHVAVNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQLLLQHGANVNA
150 160 170 180 190 200
440 450 460 470 480 490
pF1KE1 RMLNGCTPLHLAAGRGLMGISSTLCKAGADSLLRNVEDETPQDLTEESLVLLPFDDLKIS
.: .: . :: :.::::. . :: ..:::: :.: ...::
XP_011 QMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVARSRRVSRGSCGHAPC
210 220 230 240 250 260
500
pF1KE1 GKLLLCTD
XP_011 TRVSAGWLQVIDILRGKATRPASTSQPDPSPDRSANTSPESSSRLSSNGLLSASPSSSPS
270 280 290 300 310 320
>>NP_065390 (OMIM: 164008,612132) NF-kappa-B inhibitor a (317 aa)
initn: 457 init1: 237 opt: 483 Z-score: 265.2 bits: 57.9 E(85289): 5e-08
Smith-Waterman score: 483; 37.6% identity (65.6% similar) in 250 aa overlap (255-496:70-315)
230 240 250 260 270 280
pF1KE1 GGPEAEDPAPRLPLPHVGALSPQQLEALTYISEDGDTLVHLAVIHEAPAVLLCCLALLPQ
..::::...:::.::: :. . . .
NP_065 EEYEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKG
40 50 60 70 80 90
290 300 310 320 330 340
pF1KE1 EV--LDIQNNLYQTALHLAVHLDQPGAVRALVLKGASRALQDRHGDTALHVACQRQHLAC
.. :..:::: :: ::::: .:: ..::. : . :.: .:.: ::.::.. ::
NP_065 DLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS
100 110 120 130 140 150
350 360 370 380 390 400
pF1KE1 ARCLLEGRPEPGRGTSHSLDLQLQNWQGLACLHIATLQKNQPLMELLLRNGADIDVQEGT
. : .. : ::. :. :..: .:::.:... ..:::. :::...::
NP_065 VGVLTQSCTTPHL---HSI-LKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPC
160 170 180 190 200 210
410 420 430 440 450 460
pF1KE1 SGKTALHLAVETQERGLVQFLLQAGAQVDARMLNGCTPLHLAAGRGLMGISSTLCKAGAD
.:.:::::::. :. ::..::. ::.:. .: .: .:. :: :.. : . .
NP_065 NGRTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLE
220 230 240 250 260 270
470 480 490 500
pF1KE1 SL--LRNVEDE----TPQDLTEESLVLLPFDDLKISGKLLLCTD
.: : . ::: : ...:: . ::.:: ..:. :
NP_065 NLQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL
280 290 300 310
>>XP_011538132 (OMIM: 164012,615577) PREDICTED: nuclear (755 aa)
initn: 418 init1: 136 opt: 460 Z-score: 248.9 bits: 56.2 E(85289): 4e-07
Smith-Waterman score: 460; 32.8% identity (58.1% similar) in 332 aa overlap (147-473:235-559)
120 130 140 150 160 170
pF1KE1 KAARRSLEPDPAQTGPRPARAAGMSEARKGPDEAEESQYDSGIESLRSLRSLPESTSAPA
:. : :.:: . . ... :
XP_011 FGGGSHMGGGSGGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAA
210 220 230 240 250 260
180 190 200 210 220 230
pF1KE1 SGPSDGSPQPCTHPPGPVKEPQEKEDADGERADSTYGSSSLTYTLSLLGGPEAEDPAPRL
. :: : . ..: .: . :: . .: : . . .. . :. .. : .
XP_011 TVPSRDSGEEAAEPSAPSRTPQCEPQAP-EMLQRAREYNARLFGLAQRSARALLDYGV--
270 280 290 300 310 320
240 250 260 270 280 290
pF1KE1 PLPHVGALSPQQLEALTYISEDGDTLVHLAVIHEAPAVLLCCLALLPQE----VLDIQNN
. :: : . :: .:.::: .:::.:: .:. . .. . :... :.
XP_011 -TADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNH
330 340 350 360 370 380
300 310 320 330 340 350
pF1KE1 LYQTALHLAVHLDQPGAVRALVLKGASRALQDRHGDTALHVACQRQHLACARCLLEGRPE
:.:: ::::: : ..: :. ::. :: :::::.:.:.: . : : ::.. .
XP_011 LHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAG--AGAPELLRALLQ
390 400 410 420 430
360 370 380 390 400 410
pF1KE1 PGRGTSHSLDLQLQNWQGLACLHIATLQKNQPLMELLLRNGADIDVQEGTSGKTALHLAV
: . .: :.. ...:: .:.:. .. ..::. .::.... : .:.::::::.
XP_011 SGAPAVPQL-LHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLAT
440 450 460 470 480 490
420 430 440 450 460 470
pF1KE1 ETQERGLVQFLL-QAGAQVDARMLNGCTPLHLAAGRGLMGISSTLCKAGADSLLRNVEDE
: .: ::: :. . :.:.:: . : :::::::: : .. : ::::: .: :
XP_011 EMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPL
500 510 520 530 540 550
480 490 500
pF1KE1 TPQDLTEESLVLLPFDDLKISGKLLLCTD
:
XP_011 CPLPSPPTSDSDSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPS
560 570 580 590 600 610
>>XP_011538133 (OMIM: 164012,615577) PREDICTED: nuclear (755 aa)
initn: 418 init1: 136 opt: 460 Z-score: 248.9 bits: 56.2 E(85289): 4e-07
Smith-Waterman score: 460; 32.8% identity (58.1% similar) in 332 aa overlap (147-473:235-559)
120 130 140 150 160 170
pF1KE1 KAARRSLEPDPAQTGPRPARAAGMSEARKGPDEAEESQYDSGIESLRSLRSLPESTSAPA
:. : :.:: . . ... :
XP_011 FGGGSHMGGGSGGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAA
210 220 230 240 250 260
180 190 200 210 220 230
pF1KE1 SGPSDGSPQPCTHPPGPVKEPQEKEDADGERADSTYGSSSLTYTLSLLGGPEAEDPAPRL
. :: : . ..: .: . :: . .: : . . .. . :. .. : .
XP_011 TVPSRDSGEEAAEPSAPSRTPQCEPQAP-EMLQRAREYNARLFGLAQRSARALLDYGV--
270 280 290 300 310 320
240 250 260 270 280 290
pF1KE1 PLPHVGALSPQQLEALTYISEDGDTLVHLAVIHEAPAVLLCCLALLPQE----VLDIQNN
. :: : . :: .:.::: .:::.:: .:. . .. . :... :.
XP_011 -TADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNH
330 340 350 360 370 380
300 310 320 330 340 350
pF1KE1 LYQTALHLAVHLDQPGAVRALVLKGASRALQDRHGDTALHVACQRQHLACARCLLEGRPE
:.:: ::::: : ..: :. ::. :: :::::.:.:.: . : : ::.. .
XP_011 LHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAG--AGAPELLRALLQ
390 400 410 420 430
360 370 380 390 400 410
pF1KE1 PGRGTSHSLDLQLQNWQGLACLHIATLQKNQPLMELLLRNGADIDVQEGTSGKTALHLAV
: . .: :.. ...:: .:.:. .. ..::. .::.... : .:.::::::.
XP_011 SGAPAVPQL-LHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLAT
440 450 460 470 480 490
420 430 440 450 460 470
pF1KE1 ETQERGLVQFLL-QAGAQVDARMLNGCTPLHLAAGRGLMGISSTLCKAGADSLLRNVEDE
: .: ::: :. . :.:.:: . : :::::::: : .. : ::::: .: :
XP_011 EMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPL
500 510 520 530 540 550
480 490 500
pF1KE1 TPQDLTEESLVLLPFDDLKISGKLLLCTD
:
XP_011 CPLPSPPTSDSDSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPS
560 570 580 590 600 610
500 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 11:19:03 2016 done: Sun Nov 6 11:19:04 2016
Total Scan time: 12.100 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]