Result of FASTA (omim) for
pFN21AE1936
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1936, 475 aa
1>>>pF1KE1936 475 - 475 aa - 475 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2588+/-0.000322; mu= 19.3090+/- 0.020
mean_var=95.2070+/-19.319, 0's: 0 Z-trim(116.2): 261 B-trim: 0 in 0/58
Lambda= 0.131444
statistics sampled from 26977 (27279) to 26977 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.32), width: 16
Scan time: 10.360
The best scores are: opt bits E(85289)
XP_011538872 (OMIM: 111620,111750,609017) PREDICTE ( 475) 3197 616.7 4.3e-176
NP_061008 (OMIM: 111620,111750,609017) erythroid m ( 475) 3197 616.7 4.3e-176
NP_001017922 (OMIM: 111620,111750,609017) erythroi ( 475) 3197 616.7 4.3e-176
XP_006710376 (OMIM: 111620,111750,609017) PREDICTE ( 475) 3197 616.7 4.3e-176
XP_011538873 (OMIM: 111620,111750,609017) PREDICTE ( 468) 3133 604.6 1.9e-172
XP_006715046 (OMIM: 613593) PREDICTED: butyrophili ( 419) 754 153.4 1.1e-36
NP_932078 (OMIM: 613595) butyrophilin subfamily 3 ( 535) 728 148.6 4.1e-35
NP_008925 (OMIM: 613595) butyrophilin subfamily 3 ( 584) 720 147.1 1.3e-34
XP_016878725 (OMIM: 134610,249100,608107) PREDICTE ( 780) 720 147.2 1.5e-34
NP_000234 (OMIM: 134610,249100,608107) pyrin isofo ( 781) 720 147.2 1.5e-34
NP_001184162 (OMIM: 613590) butyrophilin subfamily ( 466) 696 142.4 2.5e-33
NP_008980 (OMIM: 613590) butyrophilin subfamily 2 ( 527) 696 142.5 2.7e-33
NP_006501 (OMIM: 602165) zinc finger protein RFP [ ( 513) 688 141.0 7.7e-33
XP_005248890 (OMIM: 613593) PREDICTED: butyrophili ( 506) 669 137.3 9.3e-32
XP_016865655 (OMIM: 613591) PREDICTED: butyrophili ( 461) 663 136.2 1.9e-31
XP_011512531 (OMIM: 613591) PREDICTED: butyrophili ( 461) 663 136.2 1.9e-31
NP_853509 (OMIM: 613591) butyrophilin subfamily 2 ( 407) 660 135.5 2.6e-31
XP_005248855 (OMIM: 613591) PREDICTED: butyrophili ( 407) 660 135.5 2.6e-31
XP_016865656 (OMIM: 613591) PREDICTED: butyrophili ( 407) 660 135.5 2.6e-31
NP_001184166 (OMIM: 613591) butyrophilin subfamily ( 523) 660 135.7 3.1e-31
XP_006715016 (OMIM: 613591) PREDICTED: butyrophili ( 523) 660 135.7 3.1e-31
XP_005248854 (OMIM: 613591) PREDICTED: butyrophili ( 523) 660 135.7 3.1e-31
NP_008926 (OMIM: 613591) butyrophilin subfamily 2 ( 523) 660 135.7 3.1e-31
XP_011512530 (OMIM: 613591) PREDICTED: butyrophili ( 523) 660 135.7 3.1e-31
NP_001138480 (OMIM: 613593) butyrophilin subfamily ( 461) 658 135.2 3.7e-31
NP_008979 (OMIM: 613593) butyrophilin subfamily 3 ( 513) 658 135.3 4e-31
NP_001723 (OMIM: 601610) butyrophilin subfamily 1 ( 526) 658 135.3 4e-31
NP_003132 (OMIM: 109092) E3 ubiquitin-protein liga ( 475) 657 135.0 4.3e-31
XP_005249397 (OMIM: 601610) PREDICTED: butyrophili ( 626) 658 135.4 4.6e-31
NP_742013 (OMIM: 605700) E3 ubiquitin-protein liga ( 488) 651 133.9 9.6e-31
NP_067076 (OMIM: 605700) E3 ubiquitin-protein liga ( 518) 651 133.9 1e-30
XP_011512533 (OMIM: 613591) PREDICTED: butyrophili ( 313) 643 132.2 2e-30
NP_001184168 (OMIM: 613591) butyrophilin subfamily ( 313) 643 132.2 2e-30
NP_001229732 (OMIM: 613595) butyrophilin subfamily ( 374) 630 129.8 1.3e-29
NP_001291425 (OMIM: 613184) E3 ubiquitin-protein l ( 262) 621 128.0 3.2e-29
NP_060543 (OMIM: 613184) E3 ubiquitin-protein liga ( 485) 621 128.2 4.9e-29
NP_001288073 (OMIM: 616017) E3 ubiquitin-protein l ( 296) 586 121.4 3.5e-27
NP_542783 (OMIM: 616017) E3 ubiquitin-protein liga ( 341) 586 121.4 3.9e-27
NP_892030 (OMIM: 616017) E3 ubiquitin-protein liga ( 500) 586 121.6 5e-27
NP_001288074 (OMIM: 616017) E3 ubiquitin-protein l ( 279) 581 120.4 6.5e-27
XP_011542587 (OMIM: 607868) PREDICTED: E3 ubiquiti ( 391) 581 120.5 8.2e-27
XP_016857901 (OMIM: 607868) PREDICTED: E3 ubiquiti ( 467) 581 120.6 9.2e-27
NP_660215 (OMIM: 607868) E3 ubiquitin-protein liga ( 468) 581 120.6 9.3e-27
NP_001288075 (OMIM: 616017) E3 ubiquitin-protein l ( 263) 576 119.4 1.2e-26
NP_001317412 (OMIM: 616755) E3 ubiquitin-protein l ( 354) 527 110.3 9.2e-24
NP_060677 (OMIM: 616755) E3 ubiquitin-protein liga ( 475) 527 110.4 1.1e-23
XP_016857119 (OMIM: 616755) PREDICTED: E3 ubiquiti ( 544) 527 110.5 1.2e-23
XP_016857118 (OMIM: 616755) PREDICTED: E3 ubiquiti ( 555) 527 110.5 1.3e-23
XP_011532955 (OMIM: 615606) PREDICTED: butyrophili ( 292) 509 106.8 8.6e-23
NP_001153182 (OMIM: 615606) butyrophilin-like prot ( 316) 509 106.8 9.1e-23
>>XP_011538872 (OMIM: 111620,111750,609017) PREDICTED: e (475 aa)
initn: 3197 init1: 3197 opt: 3197 Z-score: 3282.4 bits: 616.7 E(85289): 4.3e-176
Smith-Waterman score: 3197; 99.8% identity (100.0% similar) in 475 aa overlap (1-475:1-475)
10 20 30 40 50 60
pF1KE1 MEMASSAGSWLSGCLIPLVFLRLSVYVSGHAGDAGKFHVALLGGTAELLCPLSLWPGTVP
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
XP_011 MEMASSAGSWLSGCLIPLVFLRLSVHVSGHAGDAGKFHVALLGGTAELLCPLSLWPGTVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KEVRWLRSPFPQRSQAVHIFRDGKDQDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEVRWLRSPFPQRSQAVHIFRDGKDQDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLED
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QGSYRCLIQVGNLSKEDTVILQVAAPSVGSLSPSAVALAVILPVLVLLIMVCLCLIWKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGSYRCLIQVGNLSKEDTVILQVAAPSVGSLSPSAVALAVILPVLVLLIMVCLCLIWKQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 DKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEE
370 380 390 400 410 420
430 440 450 460 470
pF1KE1 SIVPRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIVPRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
430 440 450 460 470
>>NP_061008 (OMIM: 111620,111750,609017) erythroid membr (475 aa)
initn: 3197 init1: 3197 opt: 3197 Z-score: 3282.4 bits: 616.7 E(85289): 4.3e-176
Smith-Waterman score: 3197; 99.8% identity (100.0% similar) in 475 aa overlap (1-475:1-475)
10 20 30 40 50 60
pF1KE1 MEMASSAGSWLSGCLIPLVFLRLSVYVSGHAGDAGKFHVALLGGTAELLCPLSLWPGTVP
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
NP_061 MEMASSAGSWLSGCLIPLVFLRLSVHVSGHAGDAGKFHVALLGGTAELLCPLSLWPGTVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KEVRWLRSPFPQRSQAVHIFRDGKDQDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 KEVRWLRSPFPQRSQAVHIFRDGKDQDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLED
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QGSYRCLIQVGNLSKEDTVILQVAAPSVGSLSPSAVALAVILPVLVLLIMVCLCLIWKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 QGSYRCLIQVGNLSKEDTVILQVAAPSVGSLSPSAVALAVILPVLVLLIMVCLCLIWKQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 DKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEE
370 380 390 400 410 420
430 440 450 460 470
pF1KE1 SIVPRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SIVPRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
430 440 450 460 470
>>NP_001017922 (OMIM: 111620,111750,609017) erythroid me (475 aa)
initn: 3197 init1: 3197 opt: 3197 Z-score: 3282.4 bits: 616.7 E(85289): 4.3e-176
Smith-Waterman score: 3197; 99.8% identity (100.0% similar) in 475 aa overlap (1-475:1-475)
10 20 30 40 50 60
pF1KE1 MEMASSAGSWLSGCLIPLVFLRLSVYVSGHAGDAGKFHVALLGGTAELLCPLSLWPGTVP
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
NP_001 MEMASSAGSWLSGCLIPLVFLRLSVHVSGHAGDAGKFHVALLGGTAELLCPLSLWPGTVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KEVRWLRSPFPQRSQAVHIFRDGKDQDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEVRWLRSPFPQRSQAVHIFRDGKDQDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLED
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QGSYRCLIQVGNLSKEDTVILQVAAPSVGSLSPSAVALAVILPVLVLLIMVCLCLIWKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGSYRCLIQVGNLSKEDTVILQVAAPSVGSLSPSAVALAVILPVLVLLIMVCLCLIWKQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 DKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEE
370 380 390 400 410 420
430 440 450 460 470
pF1KE1 SIVPRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIVPRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
430 440 450 460 470
>>XP_006710376 (OMIM: 111620,111750,609017) PREDICTED: e (475 aa)
initn: 3197 init1: 3197 opt: 3197 Z-score: 3282.4 bits: 616.7 E(85289): 4.3e-176
Smith-Waterman score: 3197; 99.8% identity (100.0% similar) in 475 aa overlap (1-475:1-475)
10 20 30 40 50 60
pF1KE1 MEMASSAGSWLSGCLIPLVFLRLSVYVSGHAGDAGKFHVALLGGTAELLCPLSLWPGTVP
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
XP_006 MEMASSAGSWLSGCLIPLVFLRLSVHVSGHAGDAGKFHVALLGGTAELLCPLSLWPGTVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KEVRWLRSPFPQRSQAVHIFRDGKDQDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEVRWLRSPFPQRSQAVHIFRDGKDQDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLED
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QGSYRCLIQVGNLSKEDTVILQVAAPSVGSLSPSAVALAVILPVLVLLIMVCLCLIWKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QGSYRCLIQVGNLSKEDTVILQVAAPSVGSLSPSAVALAVILPVLVLLIMVCLCLIWKQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 DKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEE
370 380 390 400 410 420
430 440 450 460 470
pF1KE1 SIVPRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SIVPRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
430 440 450 460 470
>>XP_011538873 (OMIM: 111620,111750,609017) PREDICTED: e (468 aa)
initn: 1776 init1: 1776 opt: 3133 Z-score: 3216.9 bits: 604.6 E(85289): 1.9e-172
Smith-Waterman score: 3133; 98.3% identity (98.5% similar) in 475 aa overlap (1-475:1-468)
10 20 30 40 50 60
pF1KE1 MEMASSAGSWLSGCLIPLVFLRLSVYVSGHAGDAGKFHVALLGGTAELLCPLSLWPGTVP
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
XP_011 MEMASSAGSWLSGCLIPLVFLRLSVHVSGHAGDAGKFHVALLGGTAELLCPLSLWPGTVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KEVRWLRSPFPQRSQAVHIFRDGKDQDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEVRWLRSPFPQRSQAVHIFRDGKDQDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLED
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QGSYRCLIQVGNLSKEDTVILQVAAPSVGSLSPSAVALAVILPVLVLLIMVCLCLIWKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGSYRCLIQVGNLSKEDTVILQVAAPSVGSLSPSAVALAVILPVLVLLIMVCLCLIWKQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAV
::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_011 RAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVK-------LKRAAANSGWRRARLHFVAV
190 200 210 220 230
250 260 270 280 290 300
pF1KE1 TLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVG
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 DKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGI
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE1 FLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEE
360 370 380 390 400 410
430 440 450 460 470
pF1KE1 SIVPRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIVPRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
420 430 440 450 460
>>XP_006715046 (OMIM: 613593) PREDICTED: butyrophilin su (419 aa)
initn: 746 init1: 547 opt: 754 Z-score: 779.3 bits: 153.4 E(85289): 1.1e-36
Smith-Waterman score: 825; 37.1% identity (64.1% similar) in 410 aa overlap (1-395:1-404)
10 20 30 40 50
pF1KE1 MEMASSAGSWLSGCLIPLVFLRLSVYVSGH---AGDAGKFHVALLGGTAELLCPLSLWPG
:.::: . : . . :..:.: . :.. : .: . .:..: :.: : : .
XP_006 MKMASFLAFLLLNFRVCLLLLQLLMPHSAQFSVLGPSGPI-LAMVGEDADLPCHLFPTMS
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TVPKEVRWLRSPFPQRSQAVHIFRDGKDQDEDLMPEYKGRTVLVRDA-QEGSVTLQILDV
. :..:. : . :.:... :::. .. :.::: ..::. :...:.: .:
XP_006 AETMELKWVSSSL---RQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 RLEDQGSYRCLIQVGNLSKEDTVILQVAAPSVGSLSPSAVALAVILPVLVLLIMVCLCLI
:.:.: : .: :.. .. : :.:: : : . .::: ::::.::. ..
XP_006 TASDSGKYLCYFQDGDFYEKALVELKVADPFFRSAQRWIAALAGTLPVLLLLLGGAGYFL
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 WKQRRAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVK-KLRSELKLK---------RAAA
:.:.. :. . .. : . : . : : ..... :: ::. . : .:
XP_006 WQQQEEKKTQFRKKKREQE--LREMAWSTMKQEQSTRVKLLEELRWRSIQYASRGERHSA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 NSGWRRARLHFVAVTLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSE
. :..: .. . : ::: ::.: :..::::: :. . . : .::::.::.. .:: :
XP_006 YNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCE
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 YFTTGCHYWEVYVGDKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQ
: .: ::::: :::. .: .::::..:.::: : .: :: : . . ::.:..:: :.
XP_006 SFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPR
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE1 TSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIFTFTH-NFSGPLRPFFEPCLHDGGKN
:...: .::. ::.:::::.: :::::... ::: :: .:: : : :
XP_006 TNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTAL
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE1 TAPLVICSELHKSEESIVPRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGP
XP_006 TICPA
>>NP_932078 (OMIM: 613595) butyrophilin subfamily 3 memb (535 aa)
initn: 700 init1: 303 opt: 728 Z-score: 751.3 bits: 148.6 E(85289): 4.1e-35
Smith-Waterman score: 739; 39.8% identity (64.8% similar) in 347 aa overlap (116-446:168-508)
90 100 110 120 130 140
pF1KE1 QDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLEDQGSYRCLIQVGNLSKEDTVILQVAA
.: . :. :.:. . :. : :. ...:
NP_932 SDTKGENIPAVEAPVVADGVGLYAVAASVIMRGSSGGGVSCIIRNSLLGLEKTASISIAD
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE1 PSVGSLSPSAVALAVILPVLVLLIMVCLCLIWKQRRAKEKLLYEHVTEVDNLLSDH---A
: : .: .::: ::. .::. ..:.:. :::. . :: . ... :
NP_932 PFFRSAQPWIAALAGTLPISLLLLAGASYFLWRQQ--KEKIALSRETEREREMKEMGYAA
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE1 KEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAVTLDPDTAHPKLILSEDQRCVRL
:. . .:.. . ... : :. : .. . : ::::::. :..::::: :.
NP_932 TEQEISLREWRKIQYMARGEKSLAYHEWKMALFKPADVILDPDTANAILLVSEDQRSVQR
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE1 GDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVGDKTKWILGVCSESVSRK-GKVT
... . .::::.::.. .:: : ::.: ::::: :::. .: .::::..: :: : :
NP_932 AEEPRDLPDNPERFEWRYCVLGCENFTSGRHYWEVEVGDRKEWHIGVCSKNVERKKGWVK
320 330 340 350 360 370
330 340 350 360 370 380
pF1KE1 ASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIF
.: ::.: . . ::.:.::: :.:...: :::: ::::::::.: :::::.:. :::.
NP_932 MTPENGYWTMGLTDGNKYRALTEPRTNLKLPEPPRKVGIFLDYETGEISFYNATDGSHIY
380 390 400 410 420 430
390 400 410 420 430
pF1KE1 TFTH-NFSGPLRPFFEPCLHDGGKNTAPLVIC---SELHKSEE-SIVP-----RPEGKGH
:: : .:: :: : :. . :: :.:: .:...: . ..:: : :
NP_932 TFPHASFSEPLYPVFRILTLE---PTA-LTICPIPKEVESSPDPDLVPDHSLETPLTPGL
440 450 460 470 480 490
440 450 460 470
pF1KE1 AN--GDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
:: :. . .:.: :::
NP_932 ANESGEPQAEVTSLLLPAHPGAEVSPSATTNQNHKLQARTEALY
500 510 520 530
>>NP_008925 (OMIM: 613595) butyrophilin subfamily 3 memb (584 aa)
initn: 700 init1: 303 opt: 720 Z-score: 742.7 bits: 147.1 E(85289): 1.3e-34
Smith-Waterman score: 734; 39.5% identity (64.4% similar) in 354 aa overlap (116-446:210-557)
90 100 110 120 130 140
pF1KE1 QDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLEDQGSYRCLIQVGNLSKEDTVILQVAA
.: . :. :.:. . :. : :. ...:
NP_008 SDTKGENIPAVEAPVVADGVGLYAVAASVIMRGSSGGGVSCIIRNSLLGLEKTASISIAD
180 190 200 210 220 230
150 160 170 180 190 200
pF1KE1 PSVGSLSPSAVALAVILPVLVLLIMVCLCLIWKQRRAKEKLLYEHVTEVDNLLSDHAKEK
: : .: .::: ::. .::. ..:.:. :::. . :: . ... .
NP_008 PFFRSAQPWIAALAGTLPISLLLLAGASYFLWRQQ--KEKIALSRETEREREMKEMGYAA
240 250 260 270 280 290
210 220 230 240 250
pF1KE1 GKLHKAVK-KLRSELKLKR---------AAANSGWRRARLHFVAVTLDPDTAHPKLILSE
. . ... ::. ::: .. . : :. : .. . : ::::::. :..::
NP_008 TEQEISLREKLQEELKWRKIQYMARGEKSLAYHEWKMALFKPADVILDPDTANAILLVSE
300 310 320 330 340 350
260 270 280 290 300 310
pF1KE1 DQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVGDKTKWILGVCSESVS
::: :. ... . .::::.::.. .:: : ::.: ::::: :::. .: .::::..:
NP_008 DQRSVQRAEEPRDLPDNPERFEWRYCVLGCENFTSGRHYWEVEVGDRKEWHIGVCSKNVE
360 370 380 390 400 410
320 330 340 350 360 370
pF1KE1 RK-GKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDYEAGVISFYNV
:: : : .: ::.: . . ::.:.::: :.:...: :::: ::::::::.: :::::.
NP_008 RKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEPPRKVGIFLDYETGEISFYNA
420 430 440 450 460 470
380 390 400 410 420
pF1KE1 TNKSHIFTFTH-NFSGPLRPFFEPCLHDGGKNTAPLVIC---SELHKSEE-SIVP-----
:. :::.:: : .:: :: : :. . :: :.:: .:...: . ..::
NP_008 TDGSHIYTFPHASFSEPLYPVFRILTLE---PTA-LTICPIPKEVESSPDPDLVPDHSLE
480 490 500 510 520 530
430 440 450 460 470
pF1KE1 RPEGKGHAN--GDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
: : :: :. . .:.: :::
NP_008 TPLTPGLANESGEPQAEVTSLLLPAHPGAEVSPSATTNQNHKLQARTEALY
540 550 560 570 580
>--
initn: 101 init1: 83 opt: 210 Z-score: 220.0 bits: 50.4 E(85289): 1.6e-05
Smith-Waterman score: 210; 31.5% identity (61.7% similar) in 149 aa overlap (1-145:1-145)
10 20 30 40 50
pF1KE1 MEMASSAGSWLSGCLIPLVFLRLSVYVSGH---AGDAGKFHVALLGGTAELLCPLSLWPG
:.:::: . : . . : ...: . :.. : .: . .:..: :.: : : .
NP_008 MKMASSLAFLLLNFHVSLFLVQLLTPCSAQFSVLGPSGPI-LAMVGEDADLPCHLFPTMS
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TVPKEVRWLRSPFPQRSQAVHIFRDGKDQDEDLMPEYKGRTVLVRDA-QEGSVTLQILDV
. :.::. : . :.:... :::. .. :.::: ..::. :...:.: .:
NP_008 AETMELRWVSSSL---RQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 RLEDQGSYRCLIQVGNLSKEDTVILQVAAPSVGSLSPSAVALAVILPVLVLLIMVCLCLI
:.:.: : .: :.. .. : :.:::
NP_008 TASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHIEVKGYEDGGIHLECRSTGWYPQPQ
120 130 140 150 160 170
>>XP_016878725 (OMIM: 134610,249100,608107) PREDICTED: p (780 aa)
initn: 711 init1: 584 opt: 720 Z-score: 741.1 bits: 147.2 E(85289): 1.5e-34
Smith-Waterman score: 720; 53.8% identity (76.9% similar) in 199 aa overlap (215-412:577-772)
190 200 210 220 230 240
pF1KE1 KLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAVTLDP
::::... . : :. : : : ::
XP_016 TTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIG---AQAHAVNVILDA
550 560 570 580 590 600
250 260 270 280 290 300
pF1KE1 DTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVGDKTK
.::.:.::.:.: . ::::.. . .::.::::: . .::: : .: .:::: :::::
XP_016 ETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTA
610 620 630 640 650 660
310 320 330 340 350 360
pF1KE1 WILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDY
::::.:. :.::::..: :: ::.:.. . . :::.: . : : . .::::. ::::.::
XP_016 WILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDY
670 680 690 700 710 720
370 380 390 400 410 420
pF1KE1 EAGVISFYNVTNKSHIFTFTH-NFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEESIV
..: ::::::: .:::.::. .:::::.:.: : .:::::::::.::
XP_016 RVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGPD
730 740 750 760 770 780
430 440 450 460 470
pF1KE1 PRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
>>NP_000234 (OMIM: 134610,249100,608107) pyrin isoform 1 (781 aa)
initn: 711 init1: 584 opt: 720 Z-score: 741.1 bits: 147.2 E(85289): 1.5e-34
Smith-Waterman score: 720; 53.8% identity (76.9% similar) in 199 aa overlap (215-412:578-773)
190 200 210 220 230 240
pF1KE1 KLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAVTLDP
::::... . : :. : : : ::
NP_000 TTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIG---AQAHAVNVILDA
550 560 570 580 590 600
250 260 270 280 290 300
pF1KE1 DTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVGDKTK
.::.:.::.:.: . ::::.. . .::.::::: . .::: : .: .:::: :::::
NP_000 ETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTA
610 620 630 640 650 660
310 320 330 340 350 360
pF1KE1 WILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDY
::::.:. :.::::..: :: ::.:.. . . :::.: . : : . .::::. ::::.::
NP_000 WILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDY
670 680 690 700 710 720
370 380 390 400 410 420
pF1KE1 EAGVISFYNVTNKSHIFTFTH-NFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEESIV
..: ::::::: .:::.::. .:::::.:.: : .:::::::::.::
NP_000 RVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGPD
730 740 750 760 770 780
430 440 450 460 470
pF1KE1 PRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF
475 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:20:59 2016 done: Sun Nov 6 19:21:01 2016
Total Scan time: 10.360 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]