Result of FASTA (omim) for
pFN21AE1921
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1921, 457 aa
1>>>pF1KE1921 457 - 457 aa - 457 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6464+/-0.000359; mu= 21.1928+/- 0.022
mean_var=72.1329+/-14.500, 0's: 0 Z-trim(114.4): 303 B-trim: 0 in 0/56
Lambda= 0.151011
statistics sampled from 23912 (24231) to 23912 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.284), width: 16
Scan time: 8.220
The best scores are: opt bits E(85289)
NP_004615 (OMIM: 192321) vasoactive intestinal pol ( 457) 3158 697.5 1.9e-200
XP_005265494 (OMIM: 192321) PREDICTED: vasoactive ( 456) 3139 693.4 3.3e-199
NP_001238814 (OMIM: 192321) vasoactive intestinal ( 430) 2936 649.1 6.6e-186
XP_011532381 (OMIM: 192321) PREDICTED: vasoactive ( 416) 2858 632.1 8.4e-181
XP_005265495 (OMIM: 192321) PREDICTED: vasoactive ( 416) 2858 632.1 8.4e-181
NP_001238811 (OMIM: 192321) vasoactive intestinal ( 416) 2858 632.1 8.4e-181
XP_005265496 (OMIM: 192321) PREDICTED: vasoactive ( 410) 2729 604.0 2.4e-172
NP_001238813 (OMIM: 192321) vasoactive intestinal ( 409) 2710 599.9 4.2e-171
XP_011532382 (OMIM: 192321) PREDICTED: vasoactive ( 351) 2342 519.6 5.2e-147
NP_001186566 (OMIM: 102981) pituitary adenylate cy ( 447) 1514 339.3 1.2e-92
NP_002971 (OMIM: 182098) secretin receptor precurs ( 440) 1447 324.7 3e-88
XP_016860159 (OMIM: 182098) PREDICTED: secretin re ( 435) 1431 321.2 3.4e-87
XP_011509923 (OMIM: 182098) PREDICTED: secretin re ( 445) 1429 320.8 4.6e-87
XP_016860161 (OMIM: 182098) PREDICTED: secretin re ( 377) 1368 307.5 4.1e-83
NP_003373 (OMIM: 601970) vasoactive intestinal pol ( 438) 1359 305.6 1.8e-82
XP_005249675 (OMIM: 102981) PREDICTED: pituitary a ( 411) 1358 305.3 2e-82
NP_001109 (OMIM: 102981) pituitary adenylate cycla ( 468) 1358 305.4 2.2e-82
XP_005249618 (OMIM: 601970) PREDICTED: vasoactive ( 463) 1352 304.1 5.3e-82
NP_001238812 (OMIM: 192321) vasoactive intestinal ( 247) 1331 299.2 8.2e-81
XP_006716170 (OMIM: 601970) PREDICTED: vasoactive ( 455) 1309 294.7 3.5e-79
XP_016860160 (OMIM: 182098) PREDICTED: secretin re ( 409) 1254 282.7 1.3e-75
NP_000814 (OMIM: 139191,612781) growth hormone-rel ( 423) 1233 278.1 3.2e-74
XP_006716171 (OMIM: 601970) PREDICTED: vasoactive ( 392) 1160 262.2 1.8e-69
NP_001295188 (OMIM: 601970) vasoactive intestinal ( 422) 1121 253.7 7e-67
XP_016867226 (OMIM: 102981) PREDICTED: pituitary a ( 475) 1072 243.1 1.2e-63
XP_011514852 (OMIM: 601970) PREDICTED: vasoactive ( 439) 1071 242.8 1.4e-63
XP_016868069 (OMIM: 601970) PREDICTED: vasoactive ( 300) 1066 241.6 2.2e-63
XP_005263787 (OMIM: 182098) PREDICTED: secretin re ( 262) 1038 235.4 1.4e-61
XP_011513565 (OMIM: 139191,612781) PREDICTED: grow ( 359) 1037 235.3 2e-61
XP_016860162 (OMIM: 182098) PREDICTED: secretin re ( 267) 1020 231.5 2.1e-60
NP_000155 (OMIM: 137241) gastric inhibitory polype ( 466) 924 210.8 6.3e-54
XP_016867227 (OMIM: 102981) PREDICTED: pituitary a ( 439) 916 209.0 2e-53
XP_016867225 (OMIM: 102981) PREDICTED: pituitary a ( 489) 916 209.1 2.2e-53
NP_001186565 (OMIM: 102981) pituitary adenylate cy ( 495) 916 209.1 2.2e-53
NP_001186564 (OMIM: 102981) pituitary adenylate cy ( 496) 916 209.1 2.2e-53
XP_006715708 (OMIM: 102981) PREDICTED: pituitary a ( 496) 916 209.1 2.2e-53
NP_001291451 (OMIM: 601970) vasoactive intestinal ( 358) 895 204.4 4.2e-52
NP_001295347 (OMIM: 137241) gastric inhibitory pol ( 430) 870 199.0 2.1e-50
NP_001733 (OMIM: 114131,166710) calcitonin recepto ( 474) 766 176.4 1.5e-43
NP_001158210 (OMIM: 114131,166710) calcitonin rece ( 474) 766 176.4 1.5e-43
XP_005265401 (OMIM: 125350,156400,168468,215045,60 ( 562) 736 169.9 1.5e-41
NP_000307 (OMIM: 125350,156400,168468,215045,60000 ( 593) 736 170.0 1.6e-41
NP_001171673 (OMIM: 125350,156400,168468,215045,60 ( 593) 736 170.0 1.6e-41
XP_016862422 (OMIM: 125350,156400,168468,215045,60 ( 593) 736 170.0 1.6e-41
XP_011532270 (OMIM: 125350,156400,168468,215045,60 ( 600) 736 170.0 1.6e-41
XP_011532269 (OMIM: 125350,156400,168468,215045,60 ( 606) 736 170.0 1.6e-41
XP_016862421 (OMIM: 125350,156400,168468,215045,60 ( 606) 736 170.0 1.6e-41
NP_001189404 (OMIM: 602034) corticotropin-releasin ( 438) 723 167.0 9.1e-41
NP_004373 (OMIM: 122561) corticotropin-releasing f ( 415) 721 166.5 1.2e-40
NP_001296445 (OMIM: 601469) parathyroid hormone 2 ( 439) 711 164.4 5.6e-40
>>NP_004615 (OMIM: 192321) vasoactive intestinal polypep (457 aa)
initn: 3158 init1: 3158 opt: 3158 Z-score: 3719.7 bits: 697.5 E(85289): 1.9e-200
Smith-Waterman score: 3158; 100.0% identity (100.0% similar) in 457 aa overlap (1-457:1-457)
10 20 30 40 50 60
pF1KE1 MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 YTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 PDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRH
370 380 390 400 410 420
430 440 450
pF1KE1 PSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV
:::::::::::::::::::::::::::::::::::::
NP_004 PSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV
430 440 450
>>XP_005265494 (OMIM: 192321) PREDICTED: vasoactive inte (456 aa)
initn: 2197 init1: 2197 opt: 3139 Z-score: 3697.3 bits: 693.4 E(85289): 3.3e-199
Smith-Waterman score: 3139; 99.8% identity (99.8% similar) in 457 aa overlap (1-457:1-456)
10 20 30 40 50 60
pF1KE1 MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
XP_005 ACGLDDKAASLDEQ-TMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH
130 140 150 160 170
190 200 210 220 230 240
pF1KE1 LFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 YTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGP
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 ILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFF
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE1 PDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRH
360 370 380 390 400 410
430 440 450
pF1KE1 PSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV
:::::::::::::::::::::::::::::::::::::
XP_005 PSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV
420 430 440 450
>>NP_001238814 (OMIM: 192321) vasoactive intestinal poly (430 aa)
initn: 2936 init1: 2936 opt: 2936 Z-score: 3458.6 bits: 649.1 E(85289): 6.6e-186
Smith-Waterman score: 2936; 99.5% identity (100.0% similar) in 429 aa overlap (29-457:2-430)
10 20 30 40 50 60
pF1KE1 MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENET
.:.:::::::::::::::::::::::::::::
NP_001 MRAGRLQEECDYVQMIEVQHKQCLEEAQLENET
10 20 30
70 80 90 100 110 120
pF1KE1 IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPI
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 ACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 LFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 YTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGP
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 ILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFF
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 PDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRH
340 350 360 370 380 390
430 440 450
pF1KE1 PSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV
:::::::::::::::::::::::::::::::::::::
NP_001 PSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV
400 410 420 430
>>XP_011532381 (OMIM: 192321) PREDICTED: vasoactive inte (416 aa)
initn: 2858 init1: 2858 opt: 2858 Z-score: 3366.9 bits: 632.1 E(85289): 8.4e-181
Smith-Waterman score: 2858; 100.0% identity (100.0% similar) in 416 aa overlap (42-457:1-416)
20 30 40 50 60 70
pF1KE1 LCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENETIGCSKMWDNLT
::::::::::::::::::::::::::::::
XP_011 MIEVQHKQCLEEAQLENETIGCSKMWDNLT
10 20 30
80 90 100 110 120 130
pF1KE1 CWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE1 DEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAA
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE1 VFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSE
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE1 RKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFIL
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE1 FICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMV
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE1 FELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCS
340 350 360 370 380 390
440 450
pF1KE1 TQVSMLTRVSPGARRSSSFQAEVSLV
::::::::::::::::::::::::::
XP_011 TQVSMLTRVSPGARRSSSFQAEVSLV
400 410
>>XP_005265495 (OMIM: 192321) PREDICTED: vasoactive inte (416 aa)
initn: 2858 init1: 2858 opt: 2858 Z-score: 3366.9 bits: 632.1 E(85289): 8.4e-181
Smith-Waterman score: 2858; 100.0% identity (100.0% similar) in 416 aa overlap (42-457:1-416)
20 30 40 50 60 70
pF1KE1 LCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENETIGCSKMWDNLT
::::::::::::::::::::::::::::::
XP_005 MIEVQHKQCLEEAQLENETIGCSKMWDNLT
10 20 30
80 90 100 110 120 130
pF1KE1 CWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE1 DEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAA
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE1 VFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSE
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE1 RKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFIL
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE1 FICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMV
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE1 FELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCS
340 350 360 370 380 390
440 450
pF1KE1 TQVSMLTRVSPGARRSSSFQAEVSLV
::::::::::::::::::::::::::
XP_005 TQVSMLTRVSPGARRSSSFQAEVSLV
400 410
>>NP_001238811 (OMIM: 192321) vasoactive intestinal poly (416 aa)
initn: 2858 init1: 2858 opt: 2858 Z-score: 3366.9 bits: 632.1 E(85289): 8.4e-181
Smith-Waterman score: 2858; 100.0% identity (100.0% similar) in 416 aa overlap (42-457:1-416)
20 30 40 50 60 70
pF1KE1 LCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENETIGCSKMWDNLT
::::::::::::::::::::::::::::::
NP_001 MIEVQHKQCLEEAQLENETIGCSKMWDNLT
10 20 30
80 90 100 110 120 130
pF1KE1 CWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE1 DEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAA
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE1 VFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSE
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE1 RKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFIL
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE1 FICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMV
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE1 FELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCS
340 350 360 370 380 390
440 450
pF1KE1 TQVSMLTRVSPGARRSSSFQAEVSLV
::::::::::::::::::::::::::
NP_001 TQVSMLTRVSPGARRSSSFQAEVSLV
400 410
>>XP_005265496 (OMIM: 192321) PREDICTED: vasoactive inte (410 aa)
initn: 2729 init1: 2729 opt: 2729 Z-score: 3215.1 bits: 604.0 E(85289): 2.4e-172
Smith-Waterman score: 2729; 100.0% identity (100.0% similar) in 396 aa overlap (62-457:15-410)
40 50 60 70 80 90
pF1KE1 RLQEECDYVQMIEVQHKQCLEEAQLENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFK
::::::::::::::::::::::::::::::
XP_005 MRAGRRPRLGPWAGGCSKMWDNLTCWPATPRGQVVVLACPLIFK
10 20 30 40
100 110 120 130 140 150
pF1KE1 LFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYG
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE1 LSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEG
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE1 SVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTM
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE1 VWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKS
230 240 250 260 270 280
340 350 360 370 380 390
pF1KE1 DSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFL
290 300 310 320 330 340
400 410 420 430 440 450
pF1KE1 NGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTRVSPGARRSSSFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTRVSPGARRSSSFQ
350 360 370 380 390 400
pF1KE1 AEVSLV
::::::
XP_005 AEVSLV
410
>>NP_001238813 (OMIM: 192321) vasoactive intestinal poly (409 aa)
initn: 2197 init1: 2197 opt: 2710 Z-score: 3192.8 bits: 599.9 E(85289): 4.2e-171
Smith-Waterman score: 2710; 99.7% identity (99.7% similar) in 396 aa overlap (62-457:15-409)
40 50 60 70 80 90
pF1KE1 RLQEECDYVQMIEVQHKQCLEEAQLENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFK
::::::::::::::::::::::::::::::
NP_001 MRAGRRPRLGPWAGGCSKMWDNLTCWPATPRGQVVVLACPLIFK
10 20 30 40
100 110 120 130 140 150
pF1KE1 LFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYG
::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
NP_001 LFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASLDEQ-TMFYGSVKTGYTIGYG
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE1 LSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEG
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE1 SVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTM
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE1 VWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKS
230 240 250 260 270 280
340 350 360 370 380 390
pF1KE1 DSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFL
290 300 310 320 330 340
400 410 420 430 440 450
pF1KE1 NGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTRVSPGARRSSSFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTRVSPGARRSSSFQ
350 360 370 380 390 400
pF1KE1 AEVSLV
::::::
NP_001 AEVSLV
>>XP_011532382 (OMIM: 192321) PREDICTED: vasoactive inte (351 aa)
initn: 2342 init1: 2342 opt: 2342 Z-score: 2760.3 bits: 519.6 E(85289): 5.2e-147
Smith-Waterman score: 2342; 100.0% identity (100.0% similar) in 337 aa overlap (1-337:1-337)
10 20 30 40 50 60
pF1KE1 MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 YTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFF
:::::::::::::::::::::::::::::::::::::
XP_011 ILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSYASAAKPGSSRGHR
310 320 330 340 350
370 380 390 400 410 420
pF1KE1 PDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRH
>>NP_001186566 (OMIM: 102981) pituitary adenylate cyclas (447 aa)
initn: 1432 init1: 686 opt: 1514 Z-score: 1784.1 bits: 339.3 E(85289): 1.2e-92
Smith-Waterman score: 1514; 50.3% identity (76.1% similar) in 443 aa overlap (15-447:9-438)
10 20 30 40 50 60
pF1KE1 MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENET
::. : ..:: .. .: ... .. .:::. : ::
NP_001 MAGVVHVSLAALLLLPMAPA------MHSDC----IFKKEQAMCLEKIQRANEL
10 20 30 40
70 80 90 100 110
pF1KE1 IG-------CSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNV-SRSCTDEGWTH
.: : ::::.::: . :..:...:: .:..:. : .: ::.::..::.
NP_001 MGFNDSSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQDMGVVSRNCTEDGWS-
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 LEPGP-YPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLH
:: : : :::.:. . .:. ..: :::. ::.::. ::.:: .: .:: :::::
NP_001 -EPFPHYFDACGFDEYESETGDQD-YYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLH
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 CTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFF
::::.:::.::.::.::: .::::: :. .:..: ..: :::.::::.:::..:.:
NP_001 CTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYF
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 WLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINS
::..:::::.:::. .:: ::.::. : .::::.:.. . ::. :..:.: :::: .:
NP_001 WLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDS
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 S-LWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLF
. :::.::::.. ::.:::.::: :: ::.:::. ::. ..:: : :::::::::::::
NP_001 TALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLF
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE1 GVHYIMFAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQG
:.:: .::: :.: . . ..:::: .:::::::::.::::::::::::..:::: :...
NP_001 GIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNR
350 360 370 380 390 400
420 430 440 450
pF1KE1 VLGWNPKYRHPSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV
.. . :.:::: .:.:.. .::.:.:.. : : :
NP_001 YFAVDFKHRHPSLASSGVNGGTQLSILSKSSSQIRMSGLPADNLAT
410 420 430 440
457 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:51:54 2016 done: Sun Nov 6 17:51:55 2016
Total Scan time: 8.220 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]