Result of FASTA (omim) for
pFN21AE1886
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1886, 412 aa
1>>>pF1KE1886 412 - 412 aa - 412 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0977+/-0.000366; mu= 18.2805+/- 0.023
mean_var=64.4847+/-12.845, 0's: 0 Z-trim(114.1): 81 B-trim: 465 in 1/48
Lambda= 0.159715
statistics sampled from 23616 (23703) to 23616 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.278), width: 16
Scan time: 8.590
The best scores are: opt bits E(85289)
NP_001316868 (OMIM: 107970,190230,615582) transfor ( 412) 2828 660.4 2.3e-189
NP_003230 (OMIM: 107970,190230,615582) transformin ( 412) 2828 660.4 2.3e-189
NP_001316867 (OMIM: 107970,190230,615582) transfor ( 309) 2081 488.2 1.2e-137
NP_003229 (OMIM: 190220,614816) transforming growt ( 414) 1559 368.0 2.4e-101
NP_001129071 (OMIM: 190220,614816) transforming gr ( 442) 1232 292.7 1.2e-78
NP_000651 (OMIM: 131300,190180,219700) transformin ( 390) 700 170.0 8.9e-42
XP_011525544 (OMIM: 131300,190180,219700) PREDICTE ( 391) 700 170.0 8.9e-42
NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431) 374 95.0 3.9e-19
XP_016867665 (OMIM: 147290) PREDICTED: inhibin bet ( 426) 317 81.8 3.5e-15
NP_002183 (OMIM: 147290) inhibin beta A chain prep ( 426) 317 81.8 3.5e-15
XP_016867664 (OMIM: 147290) PREDICTED: inhibin bet ( 483) 317 81.9 3.9e-15
XP_016867663 (OMIM: 147290) PREDICTED: inhibin bet ( 548) 317 81.9 4.3e-15
NP_113667 (OMIM: 612031) inhibin beta E chain prep ( 350) 303 78.5 2.8e-14
XP_006719257 (OMIM: 603936) PREDICTED: growth/diff ( 407) 298 77.4 7e-14
NP_005802 (OMIM: 603936) growth/differentiation fa ( 407) 298 77.4 7e-14
NP_005250 (OMIM: 601788,614160) growth/differentia ( 375) 297 77.2 7.7e-14
NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513) 289 75.4 3.6e-13
NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455) 276 72.4 2.6e-12
XP_011527377 (OMIM: 112600,113100,200700,201250,22 ( 501) 275 72.2 3.3e-12
NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501) 275 72.2 3.3e-12
NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501) 275 72.2 3.3e-12
XP_011527625 (OMIM: 112261,112600,235200) PREDICTE ( 240) 266 69.9 7.6e-12
NP_001191 (OMIM: 112261,112600,235200) bone morpho ( 396) 266 70.0 1.1e-11
NP_002184 (OMIM: 147390) inhibin beta B chain prep ( 407) 264 69.6 1.6e-11
NP_005529 (OMIM: 601233) inhibin beta C chain prep ( 352) 260 68.6 2.7e-11
XP_016866687 (OMIM: 112265) PREDICTED: bone morpho ( 239) 258 68.1 2.7e-11
NP_878248 (OMIM: 604651) growth/differentiation fa ( 450) 259 68.5 3.9e-11
NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454) 258 68.2 4.6e-11
NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424) 247 65.7 2.5e-10
NP_001483 (OMIM: 187500,208530,217095,602880,61385 ( 372) 243 64.7 4.3e-10
NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364) 242 64.5 4.9e-10
XP_016877094 (OMIM: 112262,600625,607932) PREDICTE ( 345) 239 63.8 7.6e-10
XP_016877093 (OMIM: 112262,600625,607932) PREDICTE ( 345) 239 63.8 7.6e-10
XP_016877092 (OMIM: 112262,600625,607932) PREDICTE ( 408) 239 63.8 8.7e-10
XP_005268072 (OMIM: 112262,600625,607932) PREDICTE ( 408) 239 63.8 8.7e-10
NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408) 239 63.8 8.7e-10
NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408) 239 63.8 8.7e-10
NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402) 228 61.3 5e-09
NP_004855 (OMIM: 605312) growth/differentiation fa ( 308) 223 60.1 8.9e-09
NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472) 223 60.2 1.3e-08
NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214) 190 52.4 1.3e-06
NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347) 190 52.5 1.9e-06
NP_004953 (OMIM: 601361) growth/differentiation fa ( 478) 189 52.4 2.9e-06
NP_057288 (OMIM: 605120,615506) growth/differentia ( 429) 187 51.9 3.7e-06
NP_003231 (OMIM: 601877) left-right determination ( 366) 175 49.1 2.2e-05
NP_066277 (OMIM: 603037) left-right determination ( 366) 170 47.9 4.9e-05
NP_001165896 (OMIM: 601877) left-right determinati ( 332) 163 46.3 0.00014
XP_011541613 (OMIM: 601918) PREDICTED: growth/diff ( 276) 153 43.9 0.00058
XP_005272014 (OMIM: 601918) PREDICTED: growth/diff ( 366) 153 44.0 0.00074
XP_011541611 (OMIM: 601918) PREDICTED: growth/diff ( 366) 153 44.0 0.00074
>>NP_001316868 (OMIM: 107970,190230,615582) transforming (412 aa)
initn: 2828 init1: 2828 opt: 2828 Z-score: 3520.7 bits: 660.4 E(85289): 2.3e-189
Smith-Waterman score: 2828; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KE1 MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
370 380 390 400 410
>>NP_003230 (OMIM: 107970,190230,615582) transforming gr (412 aa)
initn: 2828 init1: 2828 opt: 2828 Z-score: 3520.7 bits: 660.4 E(85289): 2.3e-189
Smith-Waterman score: 2828; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KE1 MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
370 380 390 400 410
>>NP_001316867 (OMIM: 107970,190230,615582) transforming (309 aa)
initn: 2081 init1: 2081 opt: 2081 Z-score: 2592.3 bits: 488.2 E(85289): 1.2e-137
Smith-Waterman score: 2081; 100.0% identity (100.0% similar) in 309 aa overlap (1-309:1-309)
10 20 30 40 50 60
pF1KE1 MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST
:::::::::
NP_001 ALDTNYCFR
>>NP_003229 (OMIM: 190220,614816) transforming growth fa (414 aa)
initn: 1532 init1: 725 opt: 1559 Z-score: 1940.4 bits: 368.0 E(85289): 2.4e-101
Smith-Waterman score: 1559; 55.7% identity (79.2% similar) in 418 aa overlap (3-412:1-414)
10 20 30 40 50 60
pF1KE1 MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPT
:: .: .. .:...::.::::::.:::. .. .::.:::::::::::.::::::
NP_003 MHYC-VLSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDY
10 20 30 40 50
70 80 90 100 110
pF1KE1 VMTH-VPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNE
. :: .:...:::::.::.: ..: .: .: .. ::::::..:.:: . .:
NP_003 PEPEEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSEN-
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LAVCPKGITS--KVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRP-
:. : .. ::.::..::: .:: .:::::.:. ::... ::::::.:::.
NP_003 -AIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEFRVFRLQNPKARVPEQRIELYQILKSK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 DEHIAKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQP-N
: :::: .: . ::. .:::::::::.:.::: ... :::..::.:::: :: : :
NP_003 DLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPSN
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 GDILENIHEVMEIKFKGVDNEDDHGRGDLGRLK---KQKDHHNPHLILMMIPPHRLDNPG
. :. : : .: .: :.:. . . :: .: :... ..:::.::..: .::..
NP_003 NYIIPNKSEELEARFAGIDGTSTYTSGDQKTIKSTRKKNSGKTPHLLLMLLPSYRLESQ-
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 QGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLR
: ..:::::::. :::::...:::.:::::::..::::::.:::::: ::::.: ::::
NP_003 QTNRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLW
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 SADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
:.:: :: ::.::::.::::::::::: :::::::::::.:.:::.::::::.:::::::
NP_003 SSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS
360 370 380 390 400 410
>>NP_001129071 (OMIM: 190220,614816) transforming growth (442 aa)
initn: 1535 init1: 725 opt: 1232 Z-score: 1532.8 bits: 292.7 E(85289): 1.2e-78
Smith-Waterman score: 1516; 52.7% identity (75.2% similar) in 444 aa overlap (3-412:1-442)
10 20 30 40 50 60
pF1KE1 MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPT
:: .: .. .:...::.::::::.:::. .. .::.:::::::::::.::::::
NP_001 MHYC-VLSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDY
10 20 30 40 50
70 80 90 100 110
pF1KE1 VMTH-VPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDM---------
. :: .:...:::::.::.: ..: .: .: .. ::::::..:.::
NP_001 PEPEEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSETV
60 70 80 90 100 110
120 130 140 150
pF1KE1 ----------IQGLAEHNELAVC------PKGITSKVFR---FNVSSVEKNRTNLFRAEF
. .: .. ..: : . :: :.::..::: .:: .:::
NP_001 CPVVTTPSGSVGSLCSRQSQVLCGYLDAIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEF
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE1 RVLRVPNPSSKRNEQRIELFQILRP-DEHIAKQRYIGGKNLPTRGTAEWLSFDVTDTVRE
::.:. ::... ::::::.:::. : :::: .: . ::. .:::::::::.:.:
NP_001 RVFRLQNPKARVPEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVHE
180 190 200 210 220 230
220 230 240 250 260
pF1KE1 WLLRRESNLGLEISIHCPCHTFQP-NGDILENIHEVMEIKFKGVDNEDDHGRGDLGRLK-
:: ... :::..::.:::: :: : :. :. : : .: .: :.:. . . :: .:
NP_001 WLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYTSGDQKTIKS
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE1 --KQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQ
:... ..:::.::..: .::.. : ..:::::::. :::::...:::.:::::::..
NP_001 TRKKNSGKTPHLLLMLLPSYRLESQ-QTNRRKKRALDAAYCFRNVQDNCCLRPLYIDFKR
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE1 DLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPL
::::::.:::::: ::::.: :::: :.:: :: ::.::::.::::::::::: ::::::
NP_001 DLGWKWIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPL
360 370 380 390 400 410
390 400 410
pF1KE1 TILYYVGRTPKVEQLSNMVVKSCKCS
:::::.:.:::.::::::.:::::::
NP_001 TILYYIGKTPKIEQLSNMIVKSCKCS
420 430 440
>>NP_000651 (OMIM: 131300,190180,219700) transforming gr (390 aa)
initn: 1022 init1: 669 opt: 700 Z-score: 871.1 bits: 170.0 E(85289): 8.9e-42
Smith-Waterman score: 1093; 46.3% identity (67.3% similar) in 410 aa overlap (9-412:15-390)
10 20 30 40 50
pF1KE1 MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLT
:. : .:. . . .:::: :.:. .:.::.:::::::::::::.
NP_000 MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 SPPEPTVMTH--VPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQ
::: . .: :::::::::. .. :: : . . :..:::::. . :..
NP_000 SPPSQGEVPPGPLPEAVLALYNSTRD---RVAGESAE--PEPEPEADYYAKEVTRVLMVE
70 80 90 100 110
120 130 140 150 160
pF1KE1 GLAEHNELAVCPKGITSKVFRF-NVSSVEKNRTN---LFRAEFRVLRVPNPSSKRNEQRI
:::. : : ... : :.: ... . : :::.:.::. . . ::..
NP_000 ---THNEIYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRL----KLKVEQHV
120 130 140 150 160
170 180 190 200 210 220
pF1KE1 ELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCP
::.: . . ::.... : . :::::::: .::.:: : :...: ::
NP_000 ELYQKYSNN----SWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCS
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 CHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRL
: : .: .... ..: . ::::. .. . : :.:: : .:
NP_000 C-------DSRDN---TLQVDINGFTTGR---RGDLATIH---GMNRPFLLLMATPLERA
230 240 250 260
290 300 310 320 330 340
pF1KE1 DNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPC
.. ..:..::::::::: . :.::::: ::::::.::::::.::::::.:::: :::
NP_000 QH--LQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPC
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE1 PYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKS
::. : :: .: ::.::: :: :::.:::::: :::: :.::::: :::::::::.:.:
NP_000 PYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRS
330 340 350 360 370 380
410
pF1KE1 CKCS
::::
NP_000 CKCS
390
>>XP_011525544 (OMIM: 131300,190180,219700) PREDICTED: t (391 aa)
initn: 1022 init1: 669 opt: 700 Z-score: 871.0 bits: 170.0 E(85289): 8.9e-42
Smith-Waterman score: 1087; 46.3% identity (65.6% similar) in 410 aa overlap (9-412:15-391)
10 20 30 40 50
pF1KE1 MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLT
:. : .:. . . .:::: :.:. .:.::.:::::::::::::.
XP_011 MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 SPPEPTVMTH--VPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQ
::: . .: :::::::::. .. :: : . . :..:::::. . :..
XP_011 SPPSQGEVPPGPLPEAVLALYNSTRD---RVAGESAE--PEPEPEADYYAKEVTRVLMVE
70 80 90 100 110
120 130 140 150 160
pF1KE1 GLAEHNELAVCPKGITSKVFRF-NVSSVEKNRTN---LFRAEFRVLRVPNPSSKRNEQRI
:::. : : ... : :.: ... . : :::.:.::. . . ::..
XP_011 ---THNEIYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRL----KLKVEQHV
120 130 140 150 160
170 180 190 200 210 220
pF1KE1 ELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCP
::.: . . ::.... : . :::::::: .::.:: : :...: ::
XP_011 ELYQKYSNN----SWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCS
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 CHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRL
: : .: .: : . : : : . . : :.:: : .:
XP_011 C-------DSRDNTLQV--------DINAGFTTGRRGDLATIHGMNRPFLLLMATPLERA
230 240 250 260
290 300 310 320 330 340
pF1KE1 DNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPC
.. ..:..::::::::: . :.::::: ::::::.::::::.::::::.:::: :::
XP_011 QH--LQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPC
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE1 PYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKS
::. : :: .: ::.::: :: :::.:::::: :::: :.::::: :::::::::.:.:
XP_011 PYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRS
330 340 350 360 370 380
410
pF1KE1 CKCS
::::
XP_011 CKCS
390
>>NP_001710 (OMIM: 112267) bone morphogenetic protein 7 (431 aa)
initn: 308 init1: 115 opt: 374 Z-score: 464.5 bits: 95.0 E(85289): 3.9e-19
Smith-Waterman score: 408; 26.6% identity (56.1% similar) in 433 aa overlap (12-411:21-430)
10 20 30 40
pF1KE1 MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGH--IKKKRVEAIRGQILS
: :: : ...::.. . .: : ..... . .. .:::
NP_001 MHVRSLRAAAPHSFVALWAPLFLLRSALADFSLDNEVHSSFIHRRLRSQERREMQREILS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 KLRLTSPPEPTVM-TH--VPYQVLALYNSTRELLEEMHGEREEGCTQE-----NTESEYY
: : :.: .. : .:. .: :::. .:: : .: . .:..
NP_001 ILGLPHRPRPHLQGKHNSAPMFMLDLYNAMA--VEEGGGPGGQGFSYPYKAVFSTQGPPL
70 80 90 100 110
110 120 130 140 150
pF1KE1 A--KEIHKF---DMIQG---LAEHNELAVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRV
: .. : . ::... :.::.. :. . :::..:.. .... . ::::.
NP_001 ASLQDSHFLTDADMVMSFVNLVEHDKEFFHPR-YHHREFRFDLSKIPEGEA-VTAAEFRI
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE1 LRVPNPSSKRNEQ-RIELFQILRPDEHIAKQRYIGGKNLPTRGTAE--WLSFDVTDTVRE
. :: :: ..:.:. ::.... . . : ..: :: ::.: : .
NP_001 YKDYIRERFDNETFRISVYQVLQ--EHLGRESDLFLLDSRTLWASEEGWLVFDITATSNH
180 190 200 210 220 230
220 230 240 250 260
pF1KE1 WLLRRESNLGLEISIHC-PCHTFQPNGDIL------ENIHEVMEIKFKGVDNEDDHGRGD
:.. . ::::..:.. ....:. : .: . : ::... . :.
NP_001 WVVNPRHNLGLQLSVETLDGQSINPKLAGLIGRHGPQNKQPFMVAFFKATEVHFRSIRST
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE1 LGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYID
.. ..:. ..:. . :. : ..... .: . : . ::..
NP_001 GSKQRSQNRSKTPKNQEAL----RMANVAENSSSDQR------------QACKKHELYVS
300 310 320 330
330 340 350 360 370
pF1KE1 FRQDLGWK-WVHEPKGYYANFCSGPCPY-LRS--ADTTHSTVLGLYNTLNPEASASPCCV
:: ::::. :. :.:: : .: : : . : : :.:. : : . .:::. .:::.
NP_001 FR-DLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCA
340 350 360 370 380 390
380 390 400 410
pF1KE1 PQDLEPLTILYYVGRTPKV-EQLSNMVVKSCKCS
: .:. ...::. . . .. ::::..: :
NP_001 PTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH
400 410 420 430
>>XP_016867665 (OMIM: 147290) PREDICTED: inhibin beta A (426 aa)
initn: 285 init1: 129 opt: 317 Z-score: 393.5 bits: 81.8 E(85289): 3.5e-15
Smith-Waterman score: 412; 26.7% identity (56.6% similar) in 408 aa overlap (31-412:46-426)
10 20 30 40 50 60
pF1KE1 MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPT
: . . . :::.. .::. :.: . .:
XP_016 IIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKK--RPD
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE1 VMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNEL
: :: :: :. :.: : : . :: : .. .: . . . .:.
XP_016 VTQPVPKA--ALLNAIRKL----H----VGKVGENGYVEIEDDIGRRAEMNELMEQTSEI
80 90 100 110 120
130 140 150 160 170
pF1KE1 AVCPK-GITSKVFRFNVSSVEKNRTNLFRAEFRV-LRVPNPSSKRNEQRIELFQILR-PD
. . : . :...:..:. .. . . ::: . :.::. . :.. :.::: . :.
XP_016 ITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQ
130 140 150 160 170 180
180 190 200 210 220
pF1KE1 EHI-----AKQRYIGG---------KNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEI
. :.. . : : . .: .. : : :...... : . .:.: ..:
XP_016 GSLDTGEEAEEVGLKGERSELLLSEKVVDARKST-WHVFPVSSSIQRLLDQGKSSLDVRI
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE1 SIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMI
. :. : .: : . . . . .: .. :.: : ..... : : .::.
XP_016 A----CEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRP--FLMLQ
250 260 270 280 290
290 300 310 320 330 340
pF1KE1 PPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWK-WVHEPKGYYAN
. :.: .:..:.:. . :. :: . ....:. :.::. :. :.::.::
XP_016 ARQSEDHPH---RRRRRGLECDGKV-NI---CCKKQFFVSFK-DIGWNDWIIAPSGYHAN
300 310 320 330 340
350 360 370 380 390
pF1KE1 FCSGPCP-YLR----SADTTHSTVLGLYNTL--NPEASASPCCVPQDLEPLTILYYV-GR
.: : :: .. :. . ::::.. : .: :. . :::: :.:...::: :.
XP_016 YCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQ
350 360 370 380 390 400
400 410
pF1KE1 TPKVEQLSNMVVKSCKCS
. ....::.:. : ::
XP_016 NIIKKDIQNMIVEECGCS
410 420
>>NP_002183 (OMIM: 147290) inhibin beta A chain prepropr (426 aa)
initn: 285 init1: 129 opt: 317 Z-score: 393.5 bits: 81.8 E(85289): 3.5e-15
Smith-Waterman score: 412; 26.7% identity (56.6% similar) in 408 aa overlap (31-412:46-426)
10 20 30 40 50 60
pF1KE1 MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPT
: . . . :::.. .::. :.: . .:
NP_002 IIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKK--RPD
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE1 VMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNEL
: :: :: :. :.: : : . :: : .. .: . . . .:.
NP_002 VTQPVPKA--ALLNAIRKL----H----VGKVGENGYVEIEDDIGRRAEMNELMEQTSEI
80 90 100 110 120
130 140 150 160 170
pF1KE1 AVCPK-GITSKVFRFNVSSVEKNRTNLFRAEFRV-LRVPNPSSKRNEQRIELFQILR-PD
. . : . :...:..:. .. . . ::: . :.::. . :.. :.::: . :.
NP_002 ITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQ
130 140 150 160 170 180
180 190 200 210 220
pF1KE1 EHI-----AKQRYIGG---------KNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEI
. :.. . : : . .: .. : : :...... : . .:.: ..:
NP_002 GSLDTGEEAEEVGLKGERSELLLSEKVVDARKST-WHVFPVSSSIQRLLDQGKSSLDVRI
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE1 SIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMI
. :. : .: : . . . . .: .. :.: : ..... : : .::.
NP_002 A----CEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRP--FLMLQ
250 260 270 280 290
290 300 310 320 330 340
pF1KE1 PPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWK-WVHEPKGYYAN
. :.: .:..:.:. . :. :: . ....:. :.::. :. :.::.::
NP_002 ARQSEDHPH---RRRRRGLECDGKV-NI---CCKKQFFVSFK-DIGWNDWIIAPSGYHAN
300 310 320 330 340
350 360 370 380 390
pF1KE1 FCSGPCP-YLR----SADTTHSTVLGLYNTL--NPEASASPCCVPQDLEPLTILYYV-GR
.: : :: .. :. . ::::.. : .: :. . :::: :.:...::: :.
NP_002 YCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQ
350 360 370 380 390 400
400 410
pF1KE1 TPKVEQLSNMVVKSCKCS
. ....::.:. : ::
NP_002 NIIKKDIQNMIVEECGCS
410 420
412 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:24:29 2016 done: Sun Nov 6 14:24:31 2016
Total Scan time: 8.590 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]