Result of FASTA (omim) for
pFN21AE1885
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1885, 411 aa
1>>>pF1KE1885 411 - 411 aa - 411 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9948+/-0.000396; mu= 18.6792+/- 0.024
mean_var=76.3679+/-15.828, 0's: 0 Z-trim(111.8): 278 B-trim: 319 in 1/53
Lambda= 0.146764
statistics sampled from 20159 (20475) to 20159 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.24), width: 16
Scan time: 6.950
The best scores are: opt bits E(85289)
NP_001874 (OMIM: 602034) corticotropin-releasing f ( 411) 2835 610.2 2.9e-174
NP_001189411 (OMIM: 602034) corticotropin-releasin ( 410) 2816 606.2 4.8e-173
NP_001189410 (OMIM: 602034) corticotropin-releasin ( 397) 2611 562.8 5.4e-160
XP_016867241 (OMIM: 602034) PREDICTED: corticotrop ( 397) 2611 562.8 5.4e-160
NP_001189404 (OMIM: 602034) corticotropin-releasin ( 438) 2604 561.3 1.6e-159
XP_011513430 (OMIM: 602034) PREDICTED: corticotrop ( 370) 2520 543.5 3.3e-154
NP_001189412 (OMIM: 602034) corticotropin-releasin ( 387) 2520 543.5 3.4e-154
XP_011513431 (OMIM: 602034) PREDICTED: corticotrop ( 387) 2520 543.5 3.4e-154
XP_011513429 (OMIM: 602034) PREDICTED: corticotrop ( 559) 2130 461.1 3.2e-129
XP_016867240 (OMIM: 602034) PREDICTED: corticotrop ( 558) 2111 457.0 5.2e-128
NP_004373 (OMIM: 122561) corticotropin-releasing f ( 415) 2016 436.8 4.7e-122
NP_001138619 (OMIM: 122561) corticotropin-releasin ( 375) 1819 395.0 1.6e-109
NP_001289949 (OMIM: 122561) corticotropin-releasin ( 314) 1689 367.5 2.7e-101
NP_001138620 (OMIM: 122561) corticotropin-releasin ( 401) 1658 361.0 3e-99
NP_001138618 (OMIM: 122561) corticotropin-releasin ( 444) 1535 335.0 2.3e-91
NP_001289947 (OMIM: 122561) corticotropin-releasin ( 240) 1368 299.4 6.3e-81
NP_001158210 (OMIM: 114131,166710) calcitonin rece ( 474) 772 173.5 1e-42
NP_001733 (OMIM: 114131,166710) calcitonin recepto ( 474) 772 173.5 1e-42
NP_002971 (OMIM: 182098) secretin receptor precurs ( 440) 741 166.9 9.1e-41
XP_016860159 (OMIM: 182098) PREDICTED: secretin re ( 435) 724 163.3 1.1e-39
XP_011509923 (OMIM: 182098) PREDICTED: secretin re ( 445) 724 163.3 1.1e-39
NP_001258680 (OMIM: 114190) calcitonin gene-relate ( 461) 722 162.9 1.5e-39
NP_005786 (OMIM: 114190) calcitonin gene-related p ( 461) 722 162.9 1.5e-39
XP_005246291 (OMIM: 114190) PREDICTED: calcitonin ( 472) 722 162.9 1.6e-39
XP_005246289 (OMIM: 114190) PREDICTED: calcitonin ( 472) 722 162.9 1.6e-39
XP_016858640 (OMIM: 114190) PREDICTED: calcitonin ( 472) 722 162.9 1.6e-39
XP_005246288 (OMIM: 114190) PREDICTED: calcitonin ( 472) 722 162.9 1.6e-39
NP_001238813 (OMIM: 192321) vasoactive intestinal ( 409) 711 160.5 7e-39
XP_005265496 (OMIM: 192321) PREDICTED: vasoactive ( 410) 710 160.3 8.2e-39
XP_005265494 (OMIM: 192321) PREDICTED: vasoactive ( 456) 705 159.3 1.8e-38
XP_016860161 (OMIM: 182098) PREDICTED: secretin re ( 377) 704 159.0 1.9e-38
XP_011532381 (OMIM: 192321) PREDICTED: vasoactive ( 416) 704 159.0 2e-38
XP_005265495 (OMIM: 192321) PREDICTED: vasoactive ( 416) 704 159.0 2e-38
NP_001238811 (OMIM: 192321) vasoactive intestinal ( 416) 704 159.0 2e-38
NP_001238814 (OMIM: 192321) vasoactive intestinal ( 430) 704 159.0 2e-38
NP_004615 (OMIM: 192321) vasoactive intestinal pol ( 457) 704 159.0 2.1e-38
NP_001186566 (OMIM: 102981) pituitary adenylate cy ( 447) 684 154.8 4e-37
NP_003373 (OMIM: 601970) vasoactive intestinal pol ( 438) 650 147.6 5.7e-35
XP_005249618 (OMIM: 601970) PREDICTED: vasoactive ( 463) 650 147.6 6e-35
XP_016860160 (OMIM: 182098) PREDICTED: secretin re ( 409) 637 144.8 3.7e-34
XP_006716170 (OMIM: 601970) PREDICTED: vasoactive ( 455) 637 144.9 4e-34
NP_000814 (OMIM: 139191,612781) growth hormone-rel ( 423) 632 143.8 7.8e-34
XP_005249675 (OMIM: 102981) PREDICTED: pituitary a ( 411) 629 143.1 1.2e-33
NP_001109 (OMIM: 102981) pituitary adenylate cycla ( 468) 629 143.2 1.3e-33
NP_001158209 (OMIM: 114131,166710) calcitonin rece ( 508) 593 135.6 2.7e-31
NP_001295188 (OMIM: 601970) vasoactive intestinal ( 422) 575 131.7 3.4e-30
XP_011514852 (OMIM: 601970) PREDICTED: vasoactive ( 439) 562 129.0 2.3e-29
XP_006716171 (OMIM: 601970) PREDICTED: vasoactive ( 392) 558 128.1 3.9e-29
XP_011513565 (OMIM: 139191,612781) PREDICTED: grow ( 359) 547 125.7 1.8e-28
XP_005263787 (OMIM: 182098) PREDICTED: secretin re ( 262) 545 125.2 1.9e-28
>>NP_001874 (OMIM: 602034) corticotropin-releasing facto (411 aa)
initn: 2835 init1: 2835 opt: 2835 Z-score: 3249.5 bits: 610.2 E(85289): 2.9e-174
Smith-Waterman score: 2835; 100.0% identity (100.0% similar) in 411 aa overlap (1-411:1-411)
10 20 30 40 50 60
pF1KE1 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 FFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
370 380 390 400 410
>>NP_001189411 (OMIM: 602034) corticotropin-releasing fa (410 aa)
initn: 2111 init1: 2089 opt: 2816 Z-score: 3227.7 bits: 606.2 E(85289): 4.8e-173
Smith-Waterman score: 2816; 99.8% identity (99.8% similar) in 411 aa overlap (1-411:1-410)
10 20 30 40 50 60
pF1KE1 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_001 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDK-RKYDLHYRIALVVN
70 80 90 100 110
130 140 150 160 170 180
pF1KE1 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
300 310 320 330 340 350
370 380 390 400 410
pF1KE1 FFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
360 370 380 390 400 410
>>NP_001189410 (OMIM: 602034) corticotropin-releasing fa (397 aa)
initn: 2606 init1: 2606 opt: 2611 Z-score: 2993.3 bits: 562.8 E(85289): 5.4e-160
Smith-Waterman score: 2611; 99.0% identity (99.2% similar) in 383 aa overlap (29-411:15-397)
10 20 30 40 50 60
pF1KE1 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
: : .::::::::::::::::::::::::::
NP_001 MGREPWPEDRDLGFPQLFCQGPYSYCNTTLDQIGTCWPRSAAGALV
10 20 30 40
70 80 90 100 110 120
pF1KE1 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE1 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
290 300 310 320 330 340
370 380 390 400 410
pF1KE1 FFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
350 360 370 380 390
>>XP_016867241 (OMIM: 602034) PREDICTED: corticotropin-r (397 aa)
initn: 2606 init1: 2606 opt: 2611 Z-score: 2993.3 bits: 562.8 E(85289): 5.4e-160
Smith-Waterman score: 2611; 99.0% identity (99.2% similar) in 383 aa overlap (29-411:15-397)
10 20 30 40 50 60
pF1KE1 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
: : .::::::::::::::::::::::::::
XP_016 MGREPWPEDRDLGFPQLFCQGPYSYCNTTLDQIGTCWPRSAAGALV
10 20 30 40
70 80 90 100 110 120
pF1KE1 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE1 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
290 300 310 320 330 340
370 380 390 400 410
pF1KE1 FFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
350 360 370 380 390
>>NP_001189404 (OMIM: 602034) corticotropin-releasing fa (438 aa)
initn: 2604 init1: 2604 opt: 2604 Z-score: 2984.8 bits: 561.3 E(85289): 1.6e-159
Smith-Waterman score: 2604; 100.0% identity (100.0% similar) in 377 aa overlap (35-411:62-438)
10 20 30 40 50 60
pF1KE1 LLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALVERPC
::::::::::::::::::::::::::::::
NP_001 AGQSQMPKDQPLWALLEQYCHTIMTLTNLSGPYSYCNTTLDQIGTCWPRSAAGALVERPC
40 50 60 70 80 90
70 80 90 100 110 120
pF1KE1 PEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVNYLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVNYLGH
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE1 CVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESNEVWC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESNEVWC
160 170 180 190 200 210
190 200 210 220 230 240
pF1KE1 RCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAI
220 230 240 250 260 270
250 260 270 280 290 300
pF1KE1 GKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQ
280 290 300 310 320 330
310 320 330 340 350 360
pF1KE1 YRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNG
340 350 360 370 380 390
370 380 390 400 410
pF1KE1 EVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
400 410 420 430
>>XP_011513430 (OMIM: 602034) PREDICTED: corticotropin-r (370 aa)
initn: 2520 init1: 2520 opt: 2520 Z-score: 2889.6 bits: 543.5 E(85289): 3.3e-154
Smith-Waterman score: 2520; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365)
10 20 30 40 50 60
pF1KE1 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 FFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
:::::
XP_011 FFNGEGLEPV
370
>>NP_001189412 (OMIM: 602034) corticotropin-releasing fa (387 aa)
initn: 2520 init1: 2520 opt: 2520 Z-score: 2889.4 bits: 543.5 E(85289): 3.4e-154
Smith-Waterman score: 2520; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365)
10 20 30 40 50 60
pF1KE1 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 FFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
:::::
NP_001 FFNGESWVSKEAQAAGPHGREKPEQRW
370 380
>>XP_011513431 (OMIM: 602034) PREDICTED: corticotropin-r (387 aa)
initn: 2520 init1: 2520 opt: 2520 Z-score: 2889.4 bits: 543.5 E(85289): 3.4e-154
Smith-Waterman score: 2520; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365)
10 20 30 40 50 60
pF1KE1 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 FFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
:::::
XP_011 FFNGESWVSKEAQAAGPHGREKPEQRW
370 380
>>XP_011513429 (OMIM: 602034) PREDICTED: corticotropin-r (559 aa)
initn: 2127 init1: 2127 opt: 2130 Z-score: 2441.0 bits: 461.1 E(85289): 3.2e-129
Smith-Waterman score: 2130; 96.9% identity (98.1% similar) in 320 aa overlap (1-320:1-317)
10 20 30 40 50 60
pF1KE1 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
:::::: :...: : .:
XP_011 ETIQYRY-VRGSL--DPTMGTGGGHRAVPLLPGRALCPRPHPGSSLKLPEETPPLSPAAH
310 320 330 340 350
>>XP_016867240 (OMIM: 602034) PREDICTED: corticotropin-r (558 aa)
initn: 1381 init1: 1381 opt: 2111 Z-score: 2419.2 bits: 457.0 E(85289): 5.2e-128
Smith-Waterman score: 2111; 96.6% identity (97.8% similar) in 320 aa overlap (1-320:1-316)
10 20 30 40 50 60
pF1KE1 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_016 ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDK-RKYDLHYRIALVVN
70 80 90 100 110
130 140 150 160 170 180
pF1KE1 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
:::::: :...: : .:
XP_016 ETIQYRY-VRGSL--DPTMGTGGGHRAVPLLPGRALCPRPHPGSSLKLPEETPPLSPAAH
300 310 320 330 340 350
411 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:05:34 2016 done: Sun Nov 6 08:05:35 2016
Total Scan time: 6.950 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]