Result of FASTA (omim) for
pFN21AE1883
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1883, 409 aa
1>>>pF1KE1883 409 - 409 aa - 409 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3698+/-0.000466; mu= 16.4584+/- 0.029
mean_var=67.5388+/-13.595, 0's: 0 Z-trim(108.4): 130 B-trim: 80 in 1/53
Lambda= 0.156062
statistics sampled from 16324 (16455) to 16324 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.548), E-opt: 0.2 (0.193), width: 16
Scan time: 6.990
The best scores are: opt bits E(85289)
NP_001130002 (OMIM: 177010) glia-derived nexin iso ( 409) 2667 610.1 3.2e-174
XP_005246698 (OMIM: 177010) PREDICTED: glia-derive ( 410) 2647 605.6 7.3e-173
XP_016859821 (OMIM: 177010) PREDICTED: glia-derive ( 397) 2588 592.3 7.1e-169
NP_001130000 (OMIM: 177010) glia-derived nexin iso ( 397) 2588 592.3 7.1e-169
XP_016859820 (OMIM: 177010) PREDICTED: glia-derive ( 397) 2588 592.3 7.1e-169
XP_016859818 (OMIM: 177010) PREDICTED: glia-derive ( 398) 2568 587.8 1.6e-167
XP_016859819 (OMIM: 177010) PREDICTED: glia-derive ( 398) 2568 587.8 1.6e-167
NP_006207 (OMIM: 177010) glia-derived nexin isofor ( 398) 2568 587.8 1.6e-167
NP_000593 (OMIM: 173360,613329) plasminogen activa ( 402) 1012 237.4 4.7e-62
XP_016867749 (OMIM: 173360,613329) PREDICTED: plas ( 440) 841 199.0 2e-50
XP_016862107 (OMIM: 602445,604218) PREDICTED: neur ( 410) 804 190.6 6e-48
NP_001116224 (OMIM: 602445,604218) neuroserpin pre ( 410) 804 190.6 6e-48
NP_005016 (OMIM: 602445,604218) neuroserpin precur ( 410) 804 190.6 6e-48
NP_006208 (OMIM: 605587) serpin I2 isoform 2 precu ( 405) 740 176.2 1.3e-43
NP_001012303 (OMIM: 605587) serpin I2 isoform 1 pr ( 415) 740 176.2 1.3e-43
XP_011512974 (OMIM: 173321,613453) PREDICTED: serp ( 454) 661 158.4 3.2e-38
NP_001258752 (OMIM: 173321,613453) serpin B6 isofo ( 395) 659 157.9 3.9e-38
NP_001258751 (OMIM: 173321,613453) serpin B6 isofo ( 390) 658 157.7 4.5e-38
NP_001284628 (OMIM: 173321,613453) serpin B6 isofo ( 376) 657 157.5 5.1e-38
NP_004559 (OMIM: 173321,613453) serpin B6 isoform ( 376) 657 157.5 5.1e-38
NP_001258753 (OMIM: 173321,613453) serpin B6 isofo ( 376) 657 157.5 5.1e-38
NP_001284629 (OMIM: 173321,613453) serpin B6 isofo ( 376) 657 157.5 5.1e-38
XP_011512976 (OMIM: 173321,613453) PREDICTED: serp ( 376) 657 157.5 5.1e-38
XP_011512975 (OMIM: 173321,613453) PREDICTED: serp ( 376) 657 157.5 5.1e-38
NP_001258754 (OMIM: 173321,613453) serpin B6 isofo ( 376) 657 157.5 5.1e-38
XP_016866429 (OMIM: 173321,613453) PREDICTED: serp ( 380) 657 157.5 5.2e-38
NP_001182220 (OMIM: 173321,613453) serpin B6 isofo ( 380) 657 157.5 5.2e-38
XP_011512636 (OMIM: 130135) PREDICTED: leukocyte e ( 379) 650 155.9 1.5e-37
NP_109591 (OMIM: 130135) leukocyte elastase inhibi ( 379) 650 155.9 1.5e-37
XP_011512635 (OMIM: 130135) PREDICTED: leukocyte e ( 379) 650 155.9 1.5e-37
XP_005245255 (OMIM: 107300,613118) PREDICTED: anti ( 416) 615 148.1 3.9e-35
NP_000479 (OMIM: 107300,613118) antithrombin-III p ( 464) 615 148.1 4.3e-35
NP_942130 (OMIM: 601697,617115) serpin B8 isoform ( 374) 605 145.8 1.7e-34
NP_002631 (OMIM: 601697,617115) serpin B8 isoform ( 374) 605 145.8 1.7e-34
XP_005249241 (OMIM: 601799) PREDICTED: serpin B9 i ( 376) 598 144.2 5.1e-34
NP_004146 (OMIM: 601799) serpin B9 [Homo sapiens] ( 376) 598 144.2 5.1e-34
XP_016866430 (OMIM: 173321,613453) PREDICTED: serp ( 332) 583 140.8 4.8e-33
XP_011512978 (OMIM: 173321,613453) PREDICTED: serp ( 332) 583 140.8 4.8e-33
NP_002965 (OMIM: 600518) serpin B4 isoform 1 [Homo ( 390) 574 138.8 2.2e-32
XP_011524440 (OMIM: 600518) PREDICTED: serpin B4 i ( 390) 574 138.8 2.2e-32
NP_536723 (OMIM: 615682) serpin B11 isoform a [Hom ( 392) 565 136.8 9.1e-32
XP_011524553 (OMIM: 615682) PREDICTED: serpin B11 ( 392) 565 136.8 9.1e-32
XP_011512637 (OMIM: 130135) PREDICTED: leukocyte e ( 330) 557 134.9 2.8e-31
NP_008850 (OMIM: 600517) serpin B3 [Homo sapiens] ( 390) 557 135.0 3.2e-31
NP_536722 (OMIM: 615662) serpin B12 isoform 2 [Hom ( 405) 537 130.5 7.4e-30
NP_001137290 (OMIM: 173390) plasminogen activator ( 415) 537 130.5 7.6e-30
NP_002566 (OMIM: 173390) plasminogen activator inh ( 415) 537 130.5 7.6e-30
NP_001294857 (OMIM: 615662) serpin B12 isoform 1 [ ( 425) 537 130.5 7.7e-30
XP_016881556 (OMIM: 615662) PREDICTED: serpin B12 ( 425) 537 130.5 7.7e-30
XP_011524551 (OMIM: 615662) PREDICTED: serpin B12 ( 425) 537 130.5 7.7e-30
>>NP_001130002 (OMIM: 177010) glia-derived nexin isoform (409 aa)
initn: 2667 init1: 2667 opt: 2667 Z-score: 3248.7 bits: 610.1 E(85289): 3.2e-174
Smith-Waterman score: 2667; 100.0% identity (100.0% similar) in 409 aa overlap (1-409:1-409)
10 20 30 40 50 60
pF1KE1 MSDCRSSLVEGTMNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSDCRSSLVEGTMNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSE
310 320 330 340 350 360
370 380 390 400
pF1KE1 DGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
370 380 390 400
>>XP_005246698 (OMIM: 177010) PREDICTED: glia-derived ne (410 aa)
initn: 2215 init1: 2215 opt: 2647 Z-score: 3224.4 bits: 605.6 E(85289): 7.3e-173
Smith-Waterman score: 2647; 99.5% identity (99.5% similar) in 410 aa overlap (1-409:1-410)
10 20 30 40 50 60
pF1KE1 MSDCRSSLVEGTMNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSDCRSSLVEGTMNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
250 260 270 280 290 300
310 320 330 340 350
pF1KE1 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITR-SENLHVSHILQKAKIEVS
:::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_005 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVS
310 320 330 340 350 360
360 370 380 390 400
pF1KE1 EDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
370 380 390 400 410
>>XP_016859821 (OMIM: 177010) PREDICTED: glia-derived ne (397 aa)
initn: 2588 init1: 2588 opt: 2588 Z-score: 3152.8 bits: 592.3 E(85289): 7.1e-169
Smith-Waterman score: 2588; 100.0% identity (100.0% similar) in 397 aa overlap (13-409:1-397)
10 20 30 40 50 60
pF1KE1 MSDCRSSLVEGTMNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
10 20 30 40
70 80 90 100 110 120
pF1KE1 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE1 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSE
290 300 310 320 330 340
370 380 390 400
pF1KE1 DGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
350 360 370 380 390
>>NP_001130000 (OMIM: 177010) glia-derived nexin isoform (397 aa)
initn: 2588 init1: 2588 opt: 2588 Z-score: 3152.8 bits: 592.3 E(85289): 7.1e-169
Smith-Waterman score: 2588; 100.0% identity (100.0% similar) in 397 aa overlap (13-409:1-397)
10 20 30 40 50 60
pF1KE1 MSDCRSSLVEGTMNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
10 20 30 40
70 80 90 100 110 120
pF1KE1 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE1 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSE
290 300 310 320 330 340
370 380 390 400
pF1KE1 DGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
350 360 370 380 390
>>XP_016859820 (OMIM: 177010) PREDICTED: glia-derived ne (397 aa)
initn: 2588 init1: 2588 opt: 2588 Z-score: 3152.8 bits: 592.3 E(85289): 7.1e-169
Smith-Waterman score: 2588; 100.0% identity (100.0% similar) in 397 aa overlap (13-409:1-397)
10 20 30 40 50 60
pF1KE1 MSDCRSSLVEGTMNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
10 20 30 40
70 80 90 100 110 120
pF1KE1 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE1 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSE
290 300 310 320 330 340
370 380 390 400
pF1KE1 DGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
350 360 370 380 390
>>XP_016859818 (OMIM: 177010) PREDICTED: glia-derived ne (398 aa)
initn: 2136 init1: 2136 opt: 2568 Z-score: 3128.5 bits: 587.8 E(85289): 1.6e-167
Smith-Waterman score: 2568; 99.5% identity (99.5% similar) in 398 aa overlap (13-409:1-398)
10 20 30 40 50 60
pF1KE1 MSDCRSSLVEGTMNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
10 20 30 40
70 80 90 100 110 120
pF1KE1 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
230 240 250 260 270 280
310 320 330 340 350
pF1KE1 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITR-SENLHVSHILQKAKIEVS
:::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_016 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVS
290 300 310 320 330 340
360 370 380 390 400
pF1KE1 EDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
350 360 370 380 390
>>XP_016859819 (OMIM: 177010) PREDICTED: glia-derived ne (398 aa)
initn: 2136 init1: 2136 opt: 2568 Z-score: 3128.5 bits: 587.8 E(85289): 1.6e-167
Smith-Waterman score: 2568; 99.5% identity (99.5% similar) in 398 aa overlap (13-409:1-398)
10 20 30 40 50 60
pF1KE1 MSDCRSSLVEGTMNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
10 20 30 40
70 80 90 100 110 120
pF1KE1 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
230 240 250 260 270 280
310 320 330 340 350
pF1KE1 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITR-SENLHVSHILQKAKIEVS
:::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_016 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVS
290 300 310 320 330 340
360 370 380 390 400
pF1KE1 EDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
350 360 370 380 390
>>NP_006207 (OMIM: 177010) glia-derived nexin isoform a (398 aa)
initn: 2136 init1: 2136 opt: 2568 Z-score: 3128.5 bits: 587.8 E(85289): 1.6e-167
Smith-Waterman score: 2568; 99.5% identity (99.5% similar) in 398 aa overlap (13-409:1-398)
10 20 30 40 50 60
pF1KE1 MSDCRSSLVEGTMNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPH
10 20 30 40
70 80 90 100 110 120
pF1KE1 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
230 240 250 260 270 280
310 320 330 340 350
pF1KE1 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITR-SENLHVSHILQKAKIEVS
:::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
NP_006 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVS
290 300 310 320 330 340
360 370 380 390 400
pF1KE1 EDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
350 360 370 380 390
>>NP_000593 (OMIM: 173360,613329) plasminogen activator (402 aa)
initn: 986 init1: 706 opt: 1012 Z-score: 1235.0 bits: 237.4 E(85289): 4.7e-62
Smith-Waterman score: 1012; 41.4% identity (73.9% similar) in 379 aa overlap (33-409:25-402)
10 20 30 40 50 60
pF1KE1 DCRSSLVEGTMNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDN
: : . .:.:. :..::.:.... :
NP_000 MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRN
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 IVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVN--GVGKILKKINKAIVSKKNKDIV
.:.::.:.::::.:::: . :.:..:. .: . .. :.. :... : ... ::: .
NP_000 VVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
....:.::. .. :. . .:. :..:.: . : :: :::..:. ::.::
NP_000 STTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
:. .: :::::::::.::.: ::. : .:..: : .::.. .:::.:: . :
NP_000 LGKGAVDQ-LTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
..:. .:...::::::...::.:: : :. .::::. .:.. :. : . :.
NP_000 TEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLP
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSE
..::::. ...::..::. ::.:::: . .:.:.... .: :::.. :::.::::.:
NP_000 RLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNE
300 310 320 330 340 350
370 380 390 400
pF1KE1 DGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
.:: ::..:..:. :: .: .:.:::::: .::::::.::::::. .:
NP_000 SGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
360 370 380 390 400
>>XP_016867749 (OMIM: 173360,613329) PREDICTED: plasmino (440 aa)
initn: 811 init1: 531 opt: 841 Z-score: 1026.4 bits: 199.0 E(85289): 2e-50
Smith-Waterman score: 841; 38.8% identity (71.1% similar) in 353 aa overlap (33-380:25-376)
10 20 30 40 50 60
pF1KE1 DCRSSLVEGTMNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDN
: : . .:.:. :..::.:.... :
XP_016 MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRN
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 IVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVN--GVGKILKKINKAIVSKKNKDIV
.:.::.:.::::.:::: . :.:..:. .: . .. :.. :... : ... ::: .
XP_016 VVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
....:.::. .. :. . .:. :..:.: . : :: :::..:. ::.::
XP_016 STTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
:. .: :::::::::.::.: ::. : .:..: : .::.. .:::.:: . :
XP_016 LGKGAVDQ-LTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
..:. .:...::::::...::.:: : :. .::::. .:.. :. : . :.
XP_016 TEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLP
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSE
..::::. ...::..::. ::.:::: . .:.:.... .: :::.. :::.::::.:
XP_016 RLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNE
300 310 320 330 340 350
370 380 390 400
pF1KE1 DGTKASAATT---AILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
.:: ::..: . : :::
XP_016 SGTVASSSTGESGSGEAPRVSPPSPFRITGPQTRKGPRSPLGTEQLCLCSAITHSPPVSQ
360 370 380 390 400 410
409 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:59:32 2016 done: Sun Nov 6 17:59:33 2016
Total Scan time: 6.990 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]