Result of FASTA (omim) for
pFN21AE1840
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1840, 357 aa
1>>>pF1KE1840 357 - 357 aa - 357 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2432+/-0.00033; mu= 17.5929+/- 0.021
mean_var=79.2816+/-15.456, 0's: 0 Z-trim(117.1): 64 B-trim: 147 in 2/53
Lambda= 0.144042
statistics sampled from 28672 (28741) to 28672 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.337), width: 16
Scan time: 7.560
The best scores are: opt bits E(85289)
NP_003387 (OMIM: 602864) protein Wnt-9b isoform 1 ( 357) 2492 527.2 2.2e-149
XP_011523480 (OMIM: 602864) PREDICTED: protein Wnt ( 363) 2318 491.0 1.7e-138
NP_001307387 (OMIM: 602864) protein Wnt-9b isoform ( 329) 2063 438.0 1.4e-122
NP_003386 (OMIM: 602863) protein Wnt-9a precursor ( 365) 1540 329.3 8.1e-90
XP_011542573 (OMIM: 602863) PREDICTED: protein Wnt ( 295) 1400 300.2 3.9e-81
NP_110388 (OMIM: 158330,603490,611812) protein Wnt ( 351) 837 183.2 7.4e-46
XP_011539899 (OMIM: 158330,603490,611812) PREDICTE ( 373) 837 183.3 7.8e-46
NP_005421 (OMIM: 164820,615220,615221) proto-oncog ( 370) 833 182.4 1.4e-45
NP_478679 (OMIM: 601967) protein Wnt-7b precursor ( 349) 828 181.4 2.7e-45
NP_004616 (OMIM: 228930,276820,601570) protein Wnt ( 349) 824 180.5 4.8e-45
XP_011528668 (OMIM: 601967) PREDICTED: protein Wnt ( 353) 823 180.3 5.6e-45
XP_011539900 (OMIM: 158330,603490,611812) PREDICTE ( 296) 805 176.5 6.6e-44
XP_011532393 (OMIM: 228930,276820,601570) PREDICTE ( 282) 783 171.9 1.5e-42
NP_004617 (OMIM: 603699) protein Wnt-11 precursor ( 354) 745 164.1 4.3e-40
XP_005274288 (OMIM: 603699) PREDICTED: protein Wnt ( 354) 745 164.1 4.3e-40
NP_110380 (OMIM: 165330,273395) proto-oncogene Wnt ( 355) 726 160.2 6.6e-39
NP_003384 (OMIM: 601396) protein Wnt-8b precursor ( 351) 715 157.9 3.2e-38
NP_149122 (OMIM: 606359) protein Wnt-3a precursor ( 352) 714 157.7 3.7e-38
XP_011542621 (OMIM: 606359) PREDICTED: protein Wnt ( 446) 714 157.8 4.4e-38
NP_057171 (OMIM: 606267) protein Wnt-16 isoform 2 ( 355) 699 154.6 3.2e-37
NP_476509 (OMIM: 606267) protein Wnt-16 isoform 1 ( 365) 699 154.6 3.3e-37
NP_001278809 (OMIM: 601968) protein Wnt-2b isoform ( 299) 660 146.4 7.8e-35
NP_004176 (OMIM: 601968) protein Wnt-2b isoform WN ( 372) 660 146.5 9.2e-35
NP_078613 (OMIM: 601968) protein Wnt-2b isoform WN ( 391) 660 146.5 9.5e-35
XP_011543541 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 655 145.4 1.9e-34
XP_011543540 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 655 145.4 1.9e-34
XP_011543542 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 655 145.4 1.9e-34
XP_016873730 (OMIM: 603699) PREDICTED: protein Wnt ( 251) 650 144.3 2.9e-34
XP_011543543 (OMIM: 603699) PREDICTED: protein Wnt ( 251) 650 144.3 2.9e-34
NP_003382 (OMIM: 147870) protein Wnt-2 precursor [ ( 360) 642 142.7 1.2e-33
NP_490645 (OMIM: 606360) protein Wnt-8a isoform 3 ( 351) 596 133.1 8.9e-31
NP_001287868 (OMIM: 606360) protein Wnt-8a isoform ( 369) 596 133.2 9.2e-31
NP_001287867 (OMIM: 606360) protein Wnt-8a isoform ( 386) 596 133.2 9.5e-31
XP_016865314 (OMIM: 606360) PREDICTED: protein Wnt ( 391) 596 133.2 9.6e-31
XP_016865313 (OMIM: 606360) PREDICTED: protein Wnt ( 408) 596 133.2 9.9e-31
XP_011541927 (OMIM: 606360) PREDICTED: protein Wnt ( 337) 590 131.9 2e-30
XP_011537024 (OMIM: 225300,601906,617073) PREDICTE ( 267) 520 117.3 4.1e-26
XP_016875408 (OMIM: 225300,601906,617073) PREDICTE ( 267) 520 117.3 4.1e-26
NP_003385 (OMIM: 225300,601906,617073) protein Wnt ( 389) 520 117.4 5.4e-26
NP_006513 (OMIM: 604663) protein Wnt-6 precursor [ ( 365) 510 115.3 2.2e-25
NP_116031 (OMIM: 606361) protein Wnt-5b precursor ( 359) 482 109.5 1.2e-23
NP_110402 (OMIM: 606361) protein Wnt-5b precursor ( 359) 482 109.5 1.2e-23
XP_016862617 (OMIM: 164975,180700) PREDICTED: prot ( 365) 480 109.1 1.6e-23
XP_006713387 (OMIM: 164975,180700) PREDICTED: prot ( 365) 480 109.1 1.6e-23
XP_011532391 (OMIM: 164975,180700) PREDICTED: prot ( 365) 480 109.1 1.6e-23
XP_011532390 (OMIM: 164975,180700) PREDICTED: prot ( 365) 480 109.1 1.6e-23
XP_011532389 (OMIM: 164975,180700) PREDICTED: prot ( 365) 480 109.1 1.6e-23
XP_011532387 (OMIM: 164975,180700) PREDICTED: prot ( 365) 480 109.1 1.6e-23
NP_001243034 (OMIM: 164975,180700) protein Wnt-5a ( 365) 480 109.1 1.6e-23
XP_011532388 (OMIM: 164975,180700) PREDICTED: prot ( 365) 480 109.1 1.6e-23
>>NP_003387 (OMIM: 602864) protein Wnt-9b isoform 1 prec (357 aa)
initn: 2492 init1: 2492 opt: 2492 Z-score: 2802.8 bits: 527.2 E(85289): 2.2e-149
Smith-Waterman score: 2492; 99.7% identity (99.7% similar) in 357 aa overlap (1-357:1-357)
10 20 30 40 50 60
pF1KE1 MRPPPALALAGLCLLALPAAAASYFGLTGREVLTPFPGLGTAAAPAQGGAHLKQCDLLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MRPPPALALAGLCLLALPAAAASYFGLTGREVLTPFPGLGTAAAPAQGGAHLKQCDLLKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEGRTGLLKRGFKETAFLY
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_003 SRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEGRMGLLKRGFKETAFLY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RYDSAVKVSSATNEALGRLELWAPARQGSLTKGLAPRSGDLVYMEDSPSFCRPSKYSPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RYDSAVKVSSATNEALGRLELWAPARQGSLTKGLAPRSGDLVYMEDSPSFCRPSKYSPGT
250 260 270 280 290 300
310 320 330 340 350
pF1KE1 AGRVCSREASCSSLCCGRGYDTQSRLVAFSCHCQVQWCCYVECQQCVQEELVYTCKH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AGRVCSREASCSSLCCGRGYDTQSRLVAFSCHCQVQWCCYVECQQCVQEELVYTCKH
310 320 330 340 350
>>XP_011523480 (OMIM: 602864) PREDICTED: protein Wnt-9b (363 aa)
initn: 2318 init1: 2318 opt: 2318 Z-score: 2607.3 bits: 491.0 E(85289): 1.7e-138
Smith-Waterman score: 2318; 99.7% identity (99.7% similar) in 331 aa overlap (27-357:33-363)
10 20 30 40 50
pF1KE1 MRPPPALALAGLCLLALPAAAASYFGLTGREVLTPFPGLGTAAAPAQGGAHLKQCD
::::::::::::::::::::::::::::::
XP_011 GRAVSFDPLACQGLNASPGSLTSPLRRIRSLTGREVLTPFPGLGTAAAPAQGGAHLKQCD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 LLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEGRTGLLKRGFKET
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 LLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEGRMGLLKRGFKET
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 AFLYAVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFLYAVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 LGSKRGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGSKRGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 VLKLRYDSAVKVSSATNEALGRLELWAPARQGSLTKGLAPRSGDLVYMEDSPSFCRPSKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLKLRYDSAVKVSSATNEALGRLELWAPARQGSLTKGLAPRSGDLVYMEDSPSFCRPSKY
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE1 SPGTAGRVCSREASCSSLCCGRGYDTQSRLVAFSCHCQVQWCCYVECQQCVQEELVYTCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPGTAGRVCSREASCSSLCCGRGYDTQSRLVAFSCHCQVQWCCYVECQQCVQEELVYTCK
310 320 330 340 350 360
pF1KE1 H
:
XP_011 H
>>NP_001307387 (OMIM: 602864) protein Wnt-9b isoform 2 p (329 aa)
initn: 2063 init1: 2063 opt: 2063 Z-score: 2321.5 bits: 438.0 E(85289): 1.4e-122
Smith-Waterman score: 2063; 99.7% identity (99.7% similar) in 302 aa overlap (1-302:1-302)
10 20 30 40 50 60
pF1KE1 MRPPPALALAGLCLLALPAAAASYFGLTGREVLTPFPGLGTAAAPAQGGAHLKQCDLLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRPPPALALAGLCLLALPAAAASYFGLTGREVLTPFPGLGTAAAPAQGGAHLKQCDLLKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEGRTGLLKRGFKETAFLY
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_001 SRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEGRMGLLKRGFKETAFLY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RYDSAVKVSSATNEALGRLELWAPARQGSLTKGLAPRSGDLVYMEDSPSFCRPSKYSPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYDSAVKVSSATNEALGRLELWAPARQGSLTKGLAPRSGDLVYMEDSPSFCRPSKYSPGT
250 260 270 280 290 300
310 320 330 340 350
pF1KE1 AGRVCSREASCSSLCCGRGYDTQSRLVAFSCHCQVQWCCYVECQQCVQEELVYTCKH
::
NP_001 AGWSAVARSQLITTSTSRIQAILPSQLPE
310 320
>>NP_003386 (OMIM: 602863) protein Wnt-9a precursor [Hom (365 aa)
initn: 1223 init1: 453 opt: 1540 Z-score: 1733.5 bits: 329.3 E(85289): 8.1e-90
Smith-Waterman score: 1540; 61.2% identity (82.9% similar) in 356 aa overlap (6-356:12-364)
10 20 30 40 50
pF1KE1 MRPPPALALAGLCLLALPAAAASYFGLTGREVLTPFPGLGTAAAPAQGGAHLKQ
: :.. ::: .:.:::::: : :: .: : :: :: :
NP_003 MLDGSPLARWLAAAFGLTLLLAALRPSAAYFGLTGSEPLTILPLTLEPEAAAQ--AHYKA
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 CDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEGR--TGLLKRG
:: ::: :.:...:::.::.:::: .:. .. :::::::: :::::.:::: ..:::::
NP_003 CDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFERWNCTLEGRYRASLLKRG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 FKETAFLYAVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKF
:::::::::.:::.:::.::.:::::::::::::..: ::.:.::::: ::::::::.::
NP_003 FKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKYSSKF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 LSNFLGSKRGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFR
...::: .:..::::::.: ::. ::.:..:.:..::::::::::::.:::::.::.::.
NP_003 VKEFLG-RRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFH
180 190 200 210 220 230
240 250 260 270 280
pF1KE1 ETGQVLKLRYDSAVKVSSATNEALGRLELWAPAR---QGSLTKGLAPRSGDLVYMEDSPS
:.:. :: .:..:.::.:.:::: :. .: : .:. . ::. .::...::::
NP_003 EVGKHLKHKYETALKVGSTTNEAAGEAGAISPPRGRASGAGGSDPLPRTPELVHLDDSPS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 FCRPSKYSPGTAGRVCSREASCSSLCCGRGYDTQSRLVAFSCHCQVQWCCYVECQQCVQE
:: ...::::::: : :: .: :.:::::..::::.:. :.:::.:::::::.::.:.
NP_003 FCLAGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQVRWCCYVECRQCTQR
300 310 320 330 340 350
350
pF1KE1 ELVYTCKH
: :::::
NP_003 EEVYTCKG
360
>>XP_011542573 (OMIM: 602863) PREDICTED: protein Wnt-9a (295 aa)
initn: 1202 init1: 437 opt: 1400 Z-score: 1577.6 bits: 300.2 E(85289): 3.9e-81
Smith-Waterman score: 1400; 64.1% identity (87.5% similar) in 295 aa overlap (67-356:1-294)
40 50 60 70 80 90
pF1KE1 PGLGTAAAPAQGGAHLKQCDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHE
.:::.::.:::: .:. .. :::::::: :
XP_011 MCRRDPGVAETLVEAVSMSALECQFQFRFE
10 20 30
100 110 120 130 140 150
pF1KE1 RWNCSLEGR--TGLLKRGFKETAFLYAVSSAALTHTLARACSAGRMERCTCDDSPGLESR
::::.:::: ..::::::::::::::.:::.:::.::.:::::::::::::..: ::.:
XP_011 RWNCTLEGRYRASLLKRGFKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE1 QAWQWGVCGDNLKYSTKFLSNFLGSKRGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHG
.::::: ::::::::.::...::: .:..::::::.: ::. ::.:..:.:..:::::::
XP_011 EAWQWGGCGDNLKYSSKFVKEFLG-RRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHG
100 110 120 130 140
220 230 240 250 260 270
pF1KE1 VSGSCAVRTCWKQLSPFRETGQVLKLRYDSAVKVSSATNEALGRLELWAPAR---QGSLT
:::::.:::::.::.::.:.:. :: .:..:.::.:.:::: :. .: : .:.
XP_011 VSGSCTVRTCWRQLAPFHEVGKHLKHKYETALKVGSTTNEAAGEAGAISPPRGRASGAGG
150 160 170 180 190 200
280 290 300 310 320 330
pF1KE1 KGLAPRSGDLVYMEDSPSFCRPSKYSPGTAGRVCSREASCSSLCCGRGYDTQSRLVAFSC
. ::. .::...:::::: ...::::::: : :: .: :.:::::..::::.:. :
XP_011 SDPLPRTPELVHLDDSPSFCLAGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPC
210 220 230 240 250 260
340 350
pF1KE1 HCQVQWCCYVECQQCVQEELVYTCKH
.:::.:::::::.::.:.: :::::
XP_011 QCQVRWCCYVECRQCTQREEVYTCKG
270 280 290
>>NP_110388 (OMIM: 158330,603490,611812) protein Wnt-4 p (351 aa)
initn: 569 init1: 255 opt: 837 Z-score: 944.2 bits: 183.2 E(85289): 7.4e-46
Smith-Waterman score: 846; 38.9% identity (68.2% similar) in 324 aa overlap (55-356:43-351)
30 40 50 60 70 80
pF1KE1 FGLTGREVLTPFPGLGTAAAPAQGGAHLKQCDLLK-LSRRQKQLCRREPGLAETLRDAAH
:. :: : .:: :.:.:. . ...: .:.
NP_110 LVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQ
20 30 40 50 60 70
90 100 110 120 130
pF1KE1 LGLLECQFQFRHERWNCS----LEGRTGLLKRGFKETAFLYAVSSAALTHTLARACSAGR
:.. :::.:::..::::: : .. .: .:.::.::.:::... ...::::.:.
NP_110 LAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGE
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE1 MERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGSK---RGNKDLRARADAHNTH
.:.: :: . : :..::. :.::. :.. : ..:. . .: .. :: . ::..
NP_110 LEKCGCDRTVHGVSPQGFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNE
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE1 VGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDSAVKVSSATNEAL
.: ::. . .:. :::::::::: :.:::. . :::..:..:: ..:.:..:
NP_110 AGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVE-------
200 210 220 230 240
260 270 280 290 300
pF1KE1 GRLELWAPARQGSLTKGLAPRSG--------DLVYMEDSPSFCRPSKYSP--GTAGRVCS
: : :: ...:.::.. ::::.: ::.::. . : :: ::.:.
NP_110 -------PRRVGS-SRALVPRNAQFKPHTDEDLVYLEPSPDFCEQDMRSGVLGTRGRTCN
250 260 270 280 290
310 320 330 340 350
pF1KE1 REAS----CSSLCCGRGYDTQSRLVAFSCHCQVQWCCYVECQQCVQEELVYTCKH
. .. : ::::::. : . .: : :. .:::.:.:.:: . ..::.
NP_110 KTSKAIDGCELLCCGRGFHTAQVELAERCSCKFHWCCFVKCRQCQRLVELHTCR
300 310 320 330 340 350
>>XP_011539899 (OMIM: 158330,603490,611812) PREDICTED: p (373 aa)
initn: 604 init1: 255 opt: 837 Z-score: 943.9 bits: 183.3 E(85289): 7.8e-46
Smith-Waterman score: 866; 35.9% identity (64.9% similar) in 382 aa overlap (3-356:8-373)
10 20 30 40
pF1KE1 MRPPPALALAGLCLLA------LPAAAASYFGLTGREVLTPFPGLGTAAAPAQGG
:::: . ..:: :: . . : :... .: . . . .
XP_011 MTQLTPAPPPASSQGSLCSTQGKRNKRLPRTLPNQRGYEGEDT-GHIPRYLAKLSSVGSI
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 AHLKQCDLLK-LSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCS----LEG
.. . :. :: : .:: :.:.:. . ...: .:.:.. :::.:::..::::: :
XP_011 SEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCSTLDSLPV
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 RTGLLKRGFKETAFLYAVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGD
.. .: .:.::.::.:::... ...::::.:..:.: :: . : :..::. :.:
XP_011 FGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELEKCGCDRTVHGVSPQGFQWSGCSD
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 NLKYSTKFLSNFLGSK---RGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAV
:. :.. : ..:. . .: .. :: . ::...: ::. . .:. :::::::::: :
XP_011 NIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEV
180 190 200 210 220 230
230 240 250 260 270
pF1KE1 RTCWKQLSPFRETGQVLKLRYDSAVKVSSATNEALGRLELWAPARQGSLTKGLAPRSG--
.:::. . :::..:..:: ..:.:..: : : :: ...:.::..
XP_011 KTCWRAVPPFRQVGHALKEKFDGATEVE--------------PRRVGS-SRALVPRNAQF
240 250 260 270 280
280 290 300 310 320
pF1KE1 ------DLVYMEDSPSFCRPSKYSP--GTAGRVCSREAS----CSSLCCGRGYDTQSRLV
::::.: ::.::. . : :: ::.:.. .. : ::::::. : . .
XP_011 KPHTDEDLVYLEPSPDFCEQDMRSGVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAQVEL
290 300 310 320 330 340
330 340 350
pF1KE1 AFSCHCQVQWCCYVECQQCVQEELVYTCKH
: : :. .:::.:.:.:: . ..::.
XP_011 AERCSCKFHWCCFVKCRQCQRLVELHTCR
350 360 370
>>NP_005421 (OMIM: 164820,615220,615221) proto-oncogene (370 aa)
initn: 804 init1: 480 opt: 833 Z-score: 939.4 bits: 182.4 E(85289): 1.4e-45
Smith-Waterman score: 833; 37.1% identity (63.7% similar) in 372 aa overlap (12-355:17-369)
10 20 30 40
pF1KE1 MRPPPALALAGLCLLALPAAAAS-----YFGL----TGREVLTPFPGLGTAAAPA
: : ::::: :. ..:. .. ..:: .: . :.
NP_005 MGLWALLPGWVSATLLLALAALPAALAANSSGRWWGIVNVASSTNLLTDSKSLQLVLEPS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 QGGAHLKQCDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCS-----
: :::.:..: :..::. ... . . .. ::..:::..::::
NP_005 ----------LQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGP
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 -LEGRTGLLKRGFKETAFLYAVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWG
: :. ...:: .::::..:..::..::..::.:: : .: :::: . :.::
NP_005 HLFGK--IVNRGCRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWG
120 130 140 150 160
170 180 190 200 210 220
pF1KE1 VCGDNLKYSTKFLSNFLGSKRGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCA
:.::. .. : .:. : . ..::: . ::...: .: : .: :::::.::::.
NP_005 GCSDNIDFGRLFGREFVDSGEKGRDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCT
170 180 190 200 210 220
230 240 250 260 270
pF1KE1 VRTCWKQLSPFRETGQVLKLRYDSAVKV---SSATNEA----LGRLELWAPARQGSLTKG
::::: .: .: .:.::. :.:.: .: . ..:.: : ::: ::..
NP_005 VRTCWMRLPTLRAVGDVLRDRFDGASRVLYGNRGSNRASRAELLRLEPEDPAHK------
230 240 250 260 270 280
280 290 300 310 320
pF1KE1 LAPRSGDLVYMEDSPSFCRPSKY--SPGTAGRVCSREA----SCSSLCCGRGYDTQSRLV
: ::::.: ::.:: : . :::::.:. . .: ::::::. :... :
NP_005 -PPSPHDLVYFEKSPNFCTYSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRV
290 300 310 320 330 340
330 340 350
pF1KE1 AFSCHCQVQWCCYVECQQCVQEELVYTCKH
. :.: .:::.: :..:.. .... :
NP_005 TERCNCTFHWCCHVSCRNCTHTRVLHECL
350 360 370
>>NP_478679 (OMIM: 601967) protein Wnt-7b precursor [Hom (349 aa)
initn: 799 init1: 281 opt: 828 Z-score: 934.2 bits: 181.4 E(85289): 2.7e-45
Smith-Waterman score: 828; 35.5% identity (67.6% similar) in 330 aa overlap (39-356:23-349)
10 20 30 40 50 60
pF1KE1 LAGLCLLALPAAAASYFGLTGREVLTPFPGLGTAAAPAQGGAHLKQCDLLKLSRRQKQLC
::. .. . ::.. . :. ::. .:
NP_478 MHRNFRKWIFYVFLCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAIC
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 RREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEGRTGL----LKRGFKETAFLYAVSS
. .: .. ..:..:. :::.::: ::::: :. . :. : .:.:: ::...
NP_478 QSRPDAIIVIGEGAQMGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 AALTHTLARACSAGRMERCTCD-DSPGLESR-QAWQWGVCGDNLKYSTKFLSNFLGSKRG
:...:... ::: : . : :: .. : .. ..:.:: :. ...:. : :. ...
NP_478 AGVAHAVTAACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 NKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRY
.:. : . ::...: :.... .. ::::::::::...::: : :::.:..:: .:
NP_478 KKNARRLMNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 DSAVKVSSATNEALGRLELWAPARQGSLTKGLAPRSGDLVYMEDSPSFCRPSKY--SPGT
..::.: . .::. . : .: . : ::::.: ::..:. . : ::
NP_478 NAAVQVEVVRA---SRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGT
240 250 260 270 280
310 320 330 340 350
pF1KE1 AGRVCSREA----SCSSLCCGRGYDTQSRLVAFSCHCQVQWCCYVECQQCVQEELVYTCK
::.:.: . .:...::::::.:.. ...:.:. .:::.:.:. : .. :.:::
NP_478 QGRLCNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
290 300 310 320 330 340
pF1KE1 H
>>NP_004616 (OMIM: 228930,276820,601570) protein Wnt-7a (349 aa)
initn: 777 init1: 278 opt: 824 Z-score: 929.7 bits: 180.5 E(85289): 4.8e-45
Smith-Waterman score: 824; 37.0% identity (66.1% similar) in 330 aa overlap (40-356:25-349)
10 20 30 40 50 60
pF1KE1 AGLCLLALPAAAASYFGLTGREVLTPFPGLGTAAAPAQGGAHLKQCDLLK-LSRRQKQLC
: ... : :.. . :. . :. ::. .:
NP_004 MNRKARRCLGHLFLSLGMVYLRIGGFSSVVALGASII--CNKIPGLAPRQRAIC
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 RREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEG-RTGL---LKRGFKETAFLYAVSS
. .: .. .....:: :::::::. ::::: : :: . :: : .:.:: ::. .
NP_004 QSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 AALTHTLARACSAGRMERCTCD-DSPGLESR-QAWQWGVCGDNLKYSTKFLSNFLGSKRG
:...:... ::. : . : :: .. : : ..:.:: :. ...:. : . :. ...
NP_004 AGVAHAITAACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGIGFAKVFVDAREI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 NKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRY
... :. . ::...: : .. ... ::::::::::...::: : ::: : ::: .:
NP_004 KQNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 DSAVKVSSATNEALGRLELWAPARQGSLTKGLAPRSGDLVYMEDSPSFCR--PSKYSPGT
. ::.: . : . . : : : . ::::.: ::..:. : : ::
NP_004 NEAVHVEPVRASRNKRPTFLKIKKPLSYRK---PMDTDLVYIEKSPNYCEEDPVTGSVGT
240 250 260 270 280
310 320 330 340 350
pF1KE1 AGRVCSREA----SCSSLCCGRGYDTQSRLVAFSCHCQVQWCCYVECQQCVQEELVYTCK
::.:.. : .:. .::::::.:.. ...:.:. .:::::.:. : .. .::::
NP_004 QGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK
290 300 310 320 330 340
pF1KE1 H
357 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:49:15 2016 done: Sun Nov 6 13:49:16 2016
Total Scan time: 7.560 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]