Result of FASTA (omim) for
pFN21AE1831
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1831, 349 aa
1>>>pF1KE1831 349 - 349 aa - 349 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9898+/-0.000379; mu= 19.1900+/- 0.024
mean_var=81.7235+/-16.305, 0's: 0 Z-trim(113.9): 71 B-trim: 70 in 1/51
Lambda= 0.141873
statistics sampled from 23334 (23413) to 23334 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.275), width: 16
Scan time: 5.730
The best scores are: opt bits E(85289)
NP_478679 (OMIM: 601967) protein Wnt-7b precursor ( 349) 2473 515.9 5.3e-146
XP_011528668 (OMIM: 601967) PREDICTED: protein Wnt ( 353) 2296 479.6 4.3e-135
NP_004616 (OMIM: 228930,276820,601570) protein Wnt ( 349) 2026 424.4 1.9e-118
XP_011532393 (OMIM: 228930,276820,601570) PREDICTE ( 282) 1703 358.2 1.3e-98
NP_004176 (OMIM: 601968) protein Wnt-2b isoform WN ( 372) 1232 261.9 1.6e-69
NP_078613 (OMIM: 601968) protein Wnt-2b isoform WN ( 391) 1232 261.9 1.7e-69
NP_110388 (OMIM: 158330,603490,611812) protein Wnt ( 351) 1212 257.8 2.7e-68
NP_116031 (OMIM: 606361) protein Wnt-5b precursor ( 359) 1206 256.5 6.3e-68
NP_110402 (OMIM: 606361) protein Wnt-5b precursor ( 359) 1206 256.5 6.3e-68
XP_011539899 (OMIM: 158330,603490,611812) PREDICTE ( 373) 1190 253.3 6.3e-67
XP_011532389 (OMIM: 164975,180700) PREDICTED: prot ( 365) 1183 251.8 1.7e-66
XP_011532387 (OMIM: 164975,180700) PREDICTED: prot ( 365) 1183 251.8 1.7e-66
XP_016862617 (OMIM: 164975,180700) PREDICTED: prot ( 365) 1183 251.8 1.7e-66
XP_011532388 (OMIM: 164975,180700) PREDICTED: prot ( 365) 1183 251.8 1.7e-66
XP_011532390 (OMIM: 164975,180700) PREDICTED: prot ( 365) 1183 251.8 1.7e-66
NP_001243034 (OMIM: 164975,180700) protein Wnt-5a ( 365) 1183 251.8 1.7e-66
XP_006713387 (OMIM: 164975,180700) PREDICTED: prot ( 365) 1183 251.8 1.7e-66
XP_011532391 (OMIM: 164975,180700) PREDICTED: prot ( 365) 1183 251.8 1.7e-66
NP_003383 (OMIM: 164975,180700) protein Wnt-5a iso ( 380) 1183 251.9 1.7e-66
XP_016862616 (OMIM: 164975,180700) PREDICTED: prot ( 394) 1183 251.9 1.8e-66
NP_003382 (OMIM: 147870) protein Wnt-2 precursor [ ( 360) 1144 243.9 4.2e-64
NP_110380 (OMIM: 165330,273395) proto-oncogene Wnt ( 355) 1143 243.6 4.8e-64
XP_011539900 (OMIM: 158330,603490,611812) PREDICTE ( 296) 1132 241.3 2e-63
NP_057171 (OMIM: 606267) protein Wnt-16 isoform 2 ( 355) 1131 241.2 2.6e-63
NP_476509 (OMIM: 606267) protein Wnt-16 isoform 1 ( 365) 1131 241.2 2.7e-63
NP_149122 (OMIM: 606359) protein Wnt-3a precursor ( 352) 1124 239.7 7.1e-63
XP_011542621 (OMIM: 606359) PREDICTED: protein Wnt ( 446) 1124 239.8 8.3e-63
NP_001278809 (OMIM: 601968) protein Wnt-2b isoform ( 299) 1106 236.0 8.1e-62
NP_005421 (OMIM: 164820,615220,615221) proto-oncog ( 370) 976 209.5 9.6e-54
NP_004617 (OMIM: 603699) protein Wnt-11 precursor ( 354) 910 195.9 1.1e-49
XP_005274288 (OMIM: 603699) PREDICTED: protein Wnt ( 354) 910 195.9 1.1e-49
NP_003384 (OMIM: 601396) protein Wnt-8b precursor ( 351) 905 194.9 2.2e-49
XP_011543540 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 881 190.0 6.8e-48
XP_011543541 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 881 190.0 6.8e-48
XP_011543542 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 881 190.0 6.8e-48
NP_490645 (OMIM: 606360) protein Wnt-8a isoform 3 ( 351) 840 181.6 2.2e-45
NP_001287868 (OMIM: 606360) protein Wnt-8a isoform ( 369) 840 181.6 2.3e-45
XP_016865314 (OMIM: 606360) PREDICTED: protein Wnt ( 391) 840 181.7 2.4e-45
NP_003386 (OMIM: 602863) protein Wnt-9a precursor ( 365) 835 180.6 4.6e-45
NP_001287867 (OMIM: 606360) protein Wnt-8a isoform ( 386) 834 180.4 5.6e-45
XP_016865313 (OMIM: 606360) PREDICTED: protein Wnt ( 408) 834 180.5 5.8e-45
NP_003387 (OMIM: 602864) protein Wnt-9b isoform 1 ( 357) 827 179.0 1.4e-44
XP_011523480 (OMIM: 602864) PREDICTED: protein Wnt ( 363) 827 179.0 1.4e-44
XP_011542573 (OMIM: 602863) PREDICTED: protein Wnt ( 295) 812 175.8 1e-43
XP_016873730 (OMIM: 603699) PREDICTED: protein Wnt ( 251) 776 168.4 1.5e-41
XP_011543543 (OMIM: 603699) PREDICTED: protein Wnt ( 251) 776 168.4 1.5e-41
XP_011541927 (OMIM: 606360) PREDICTED: protein Wnt ( 337) 725 158.1 2.6e-38
XP_016875408 (OMIM: 225300,601906,617073) PREDICTE ( 267) 708 154.5 2.5e-37
XP_011537024 (OMIM: 225300,601906,617073) PREDICTE ( 267) 708 154.5 2.5e-37
NP_003385 (OMIM: 225300,601906,617073) protein Wnt ( 389) 708 154.6 3.2e-37
>>NP_478679 (OMIM: 601967) protein Wnt-7b precursor [Hom (349 aa)
initn: 2473 init1: 2473 opt: 2473 Z-score: 2742.1 bits: 515.9 E(85289): 5.3e-146
Smith-Waterman score: 2473; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:1-349)
10 20 30 40 50 60
pF1KE1 MHRNFRKWIFYVFLCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAICQSRPDAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_478 MHRNFRKWIFYVFLCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAICQSRPDAII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VIGEGAQMGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_478 VIGEGAQMGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKNARRLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_478 AACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKNARRLM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 NLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_478 NLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRTSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_478 VRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRTSPG
250 260 270 280 290 300
310 320 330 340
pF1KE1 ADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_478 ADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
310 320 330 340
>>XP_011528668 (OMIM: 601967) PREDICTED: protein Wnt-7b (353 aa)
initn: 2296 init1: 2296 opt: 2296 Z-score: 2546.3 bits: 479.6 E(85289): 4.3e-135
Smith-Waterman score: 2296; 100.0% identity (100.0% similar) in 325 aa overlap (25-349:29-353)
10 20 30 40 50
pF1KE1 MHRNFRKWIFYVFLCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAICQSRP
::::::::::::::::::::::::::::::::
XP_011 MLLLSPRSALVSVYCPQIFLLLSSGSYLALSSVVALGANIICNKIPGLAPRQRAICQSRP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 DAIIVIGEGAQMGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAIIVIGEGAQMGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 HAVTAACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAVTAACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKNA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 RRLMNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRLMNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 QVEVVRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVEVVRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNR
250 260 270 280 290 300
300 310 320 330 340
pF1KE1 TSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
310 320 330 340 350
>>NP_004616 (OMIM: 228930,276820,601570) protein Wnt-7a (349 aa)
initn: 2011 init1: 2011 opt: 2026 Z-score: 2247.7 bits: 424.4 E(85289): 1.9e-118
Smith-Waterman score: 2026; 77.9% identity (94.0% similar) in 349 aa overlap (1-349:1-349)
10 20 30 40 50 60
pF1KE1 MHRNFRKWIFYVFLCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAICQSRPDAII
:.:. :. . ..:: .:..:...:..::::::::.:::::::::::::::::::::::::
NP_004 MNRKARRCLGHLFLSLGMVYLRIGGFSSVVALGASIICNKIPGLAPRQRAICQSRPDAII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VIGEGAQMGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVT
:::::.:::..:::.::: ::::::::::.::::.::.:::::::::::: :::::::.:
NP_004 VIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKNARRLM
:::.:::::.::::.:::: :.. :::::::::::.:::: :.. ::::::::.::: ::
NP_004 AACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQNARTLM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 NLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEV
::::::::::.::. :.::::::::::::::::::::::.:::.:..::.::: ::.::
NP_004 NLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRTSPG
::::: ..::::.::. ::.:::.:::::::::::::::: .::::::::: ::.:.:
NP_004 VRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQ
250 260 270 280 290 300
310 320 330 340
pF1KE1 ADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
:.::: ::::::::::::..::::::::::::.:::::::::::..:::
NP_004 ASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK
310 320 330 340
>>XP_011532393 (OMIM: 228930,276820,601570) PREDICTED: p (282 aa)
initn: 1703 init1: 1703 opt: 1703 Z-score: 1891.5 bits: 358.2 E(85289): 1.3e-98
Smith-Waterman score: 1703; 79.8% identity (94.0% similar) in 282 aa overlap (68-349:1-282)
40 50 60 70 80 90
pF1KE1 CNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGINECQYQFRFGRWNCSALGEKTVFGQEL
::..:::.::: ::::::::::.::::.::
XP_011 MGLDECQFQFRNGRWNCSALGERTVFGKEL
10 20 30
100 110 120 130 140 150
pF1KE1 RVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVR
.:::::::::::: :::::::.::::.:::::.::::.:::: :.. :::::::::::.:
XP_011 KVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE1 YGIDFSRRFVDAREIKKNARRLMNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTT
::: :.. ::::::::.::: ::::::::::::.::. :.::::::::::::::::::::
XP_011 YGIGFAKVFVDAREIKQNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE1 LPKFREVGHLLKEKYNAAVQVEVVRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNY
::.:::.:..::.::: ::.:: ::::: ..::::.::. ::.:::.::::::::::::
XP_011 LPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNY
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE1 CEEDAATGSVGTQGRLCNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCN
:::: .::::::::: ::.:.: :.::: ::::::::::::..::::::::::::.::::
XP_011 CEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCN
220 230 240 250 260 270
340
pF1KE1 TCSERTEVFTCK
:::::::..:::
XP_011 TCSERTEMYTCK
280
>>NP_004176 (OMIM: 601968) protein Wnt-2b isoform WNT-2B (372 aa)
initn: 1236 init1: 429 opt: 1232 Z-score: 1369.0 bits: 261.9 E(85289): 1.6e-69
Smith-Waterman score: 1232; 52.2% identity (78.0% similar) in 322 aa overlap (31-349:46-361)
10 20 30 40 50 60
pF1KE1 MHRNFRKWIFYVFLCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAICQSRPDAII
:::: .::..::::. ::: .:: :: .
NP_004 QLKTEGSLRTAVPGIPTQSAFNKCLQRYIGALGARVICDNIPGLVSRQRQLCQRYPDIMR
20 30 40 50 60 70
70 80 90 100 110
pF1KE1 VIGEGAQMGINECQYQFRFGRWNCSALG-EKTVFGQELRVGSREAAFTYAITAAGVAHAV
.::::. : :::.::: ::::..: ..::::. . .::::::.:::..:::.::.
NP_004 SVGEGAREWIRECQHQFRHHRWNCTTLDRDHTVFGRVMLRSSREAAFVYAISSAGVVHAI
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE1 TAACSQGNLSNCGCDREKQGYYNQAEG-WKWGGCSADVRYGIDFSRRFVDAREIK-KNAR
: :::::.:: :.:: .: ... .: . ::::: ...::. :.. ::::.: . :.::
NP_004 TRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDAR
140 150 160 170 180 190
180 190 200 210 220 230
pF1KE1 RLMNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQ
:::::::. :: ... ..::::::::::::: .::: .: ::..: :...:..:::
NP_004 ALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQ
200 210 220 230 240 250
240 250 260 270 280 290
pF1KE1 VEVVRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRT
: ... . .: .: .:.. .:::::...::.:: : :.::.:: ::.:..:
NP_004 VMATQDG----ANFTAARQ--GYRRATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKT
260 270 280 290 300
300 310 320 330 340
pF1KE1 SPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
: :.:::. :::::::.: . :.: ::.::::::: :.:. : . ..: :::
NP_004 SKGTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTCKAPKKAEWL
310 320 330 340 350 360
NP_004 DQT
370
>>NP_078613 (OMIM: 601968) protein Wnt-2b isoform WNT-2B (391 aa)
initn: 1236 init1: 429 opt: 1232 Z-score: 1368.7 bits: 261.9 E(85289): 1.7e-69
Smith-Waterman score: 1232; 52.2% identity (78.0% similar) in 322 aa overlap (31-349:65-380)
10 20 30 40 50 60
pF1KE1 MHRNFRKWIFYVFLCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAICQSRPDAII
:::: .::..::::. ::: .:: :: .
NP_078 ASARLGLACLLLLLLLTLPARVDTSWWYIGALGARVICDNIPGLVSRQRQLCQRYPDIMR
40 50 60 70 80 90
70 80 90 100 110
pF1KE1 VIGEGAQMGINECQYQFRFGRWNCSALG-EKTVFGQELRVGSREAAFTYAITAAGVAHAV
.::::. : :::.::: ::::..: ..::::. . .::::::.:::..:::.::.
NP_078 SVGEGAREWIRECQHQFRHHRWNCTTLDRDHTVFGRVMLRSSREAAFVYAISSAGVVHAI
100 110 120 130 140 150
120 130 140 150 160 170
pF1KE1 TAACSQGNLSNCGCDREKQGYYNQAEG-WKWGGCSADVRYGIDFSRRFVDAREIK-KNAR
: :::::.:: :.:: .: ... .: . ::::: ...::. :.. ::::.: . :.::
NP_078 TRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDAR
160 170 180 190 200 210
180 190 200 210 220 230
pF1KE1 RLMNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQ
:::::::. :: ... ..::::::::::::: .::: .: ::..: :...:..:::
NP_078 ALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQ
220 230 240 250 260 270
240 250 260 270 280 290
pF1KE1 VEVVRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRT
: ... . .: .: .:.. .:::::...::.:: : :.::.:: ::.:..:
NP_078 VMATQDG----ANFTAARQ--GYRRATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKT
280 290 300 310 320
300 310 320 330 340
pF1KE1 SPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
: :.:::. :::::::.: . :.: ::.::::::: :.:. : . ..: :::
NP_078 SKGTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTCKAPKKAEWL
330 340 350 360 370 380
NP_078 DQT
390
>>NP_110388 (OMIM: 158330,603490,611812) protein Wnt-4 p (351 aa)
initn: 1168 init1: 397 opt: 1212 Z-score: 1347.2 bits: 257.8 E(85289): 2.7e-68
Smith-Waterman score: 1212; 49.4% identity (73.3% similar) in 352 aa overlap (3-349:8-351)
10 20 30 40 50
pF1KE1 MHRNFRKWIFYVFLCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAICQSR
:..: .: :: . .. :. :::: ... . :.:. :: :: .:.
NP_110 MSPRSCLRSLRLLVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 PDAIIVIGEGAQMGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGV
... . .:::..:.::::::: :::::.: :::. . :.:::::.:::..:::
NP_110 LEVMDSVRRGAQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAFVYAISSAGV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 AHAVTAACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKN
: ::: :::.:.: .::::: .: : :..:.::: .. ::. ::. :::.:: .:.
NP_110 AFAVTRACSSGELEKCGCDRTVHGVSPQ--GFQWSGCSDNIAYGVAFSQSFVDVRERSKG
130 140 150 160 170
180 190 200 210 220 230
pF1KE1 A---RRLMNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKY
: : ::::::::::::.. .:..::::::::::: .:::: ..: ::.::: ::::.
NP_110 ASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 NAAVQVEVVR--ASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQ
..:..:: : .:: : : :.. . . ::::.: ::..::.: .: .::.
NP_110 DGATEVEPRRVGSSRALVP---RNAQFKPHT---DEDLVYLEPSPDFCEQDMRSGVLGTR
240 250 260 270 280 290
300 310 320 330 340
pF1KE1 GRLCNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
:: ::.:: . :::. .:::::..: : . .:.::::::::::: :.. .:. ::.
NP_110 GRTCNKTSKAIDGCELLCCGRGFHTAQVELAERCSCKFHWCCFVKCRQCQRLVELHTCR
300 310 320 330 340 350
>>NP_116031 (OMIM: 606361) protein Wnt-5b precursor [Hom (359 aa)
initn: 712 init1: 712 opt: 1206 Z-score: 1340.4 bits: 256.5 E(85289): 6.3e-68
Smith-Waterman score: 1206; 49.4% identity (74.8% similar) in 326 aa overlap (32-349:42-359)
10 20 30 40 50 60
pF1KE1 HRNFRKWIFYVFLCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIV
.::. .:...:::.: :: .:: . .
NP_116 LLSSWAQLLTDANSWWSLALNPVQRPEMFIIGAQPVCSQLPGLSPGQRKLCQLYQEHMAY
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE1 IGEGAQMGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTA
:::::. ::.:::.::: :::::. . .:::. ...::::.:::.:..::::..:..
NP_116 IGEGAKTGIKECQHQFRQRRWNCSTADNASVFGRVMQIGSRETAFTHAVSAAGVVNAISR
80 90 100 110 120 130
130 140 150 160 170
pF1KE1 ACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKN------
:: .:.::.:::.: . . . : ::::. .:.:: :...:::::: .::
NP_116 ACREGELSTCGCSRTARPK-DLPRDWLWGGCGDNVEYGYRFAKEFVDAREREKNFAKGSE
140 150 160 170 180 190
180 190 200 210 220 230
pF1KE1 --ARRLMNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYN
.: ::::.::::::... .. ::::::::::. :::: : .::.:: :::::.
NP_116 EQGRVLMNLQNNEAGRRAVYKMADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKYD
200 210 220 230 240 250
240 250 260 270 280 290
pF1KE1 AAVQVEVVRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRL
.:. ..:.: .::. . . .: ::::.. ::.:: .. .:::.::::::
NP_116 SAAAMRVTRKGRLELVN-------SRFTQPTPEDLVYVDPSPDYCLRNESTGSLGTQGRL
260 270 280 290 300
300 310 320 330 340
pF1KE1 CNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
::.:: : :::. :::::::: . ..: .:.:::::::::.:. :.: .. . ::
NP_116 CNKTSEGMDGCELMCCGRGYNQFKSVQVERCHCKFHWCCFVRCKKCTEIVDQYICK
310 320 330 340 350
>>NP_110402 (OMIM: 606361) protein Wnt-5b precursor [Hom (359 aa)
initn: 712 init1: 712 opt: 1206 Z-score: 1340.4 bits: 256.5 E(85289): 6.3e-68
Smith-Waterman score: 1206; 49.4% identity (74.8% similar) in 326 aa overlap (32-349:42-359)
10 20 30 40 50 60
pF1KE1 HRNFRKWIFYVFLCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIV
.::. .:...:::.: :: .:: . .
NP_110 LLSSWAQLLTDANSWWSLALNPVQRPEMFIIGAQPVCSQLPGLSPGQRKLCQLYQEHMAY
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE1 IGEGAQMGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTA
:::::. ::.:::.::: :::::. . .:::. ...::::.:::.:..::::..:..
NP_110 IGEGAKTGIKECQHQFRQRRWNCSTADNASVFGRVMQIGSRETAFTHAVSAAGVVNAISR
80 90 100 110 120 130
130 140 150 160 170
pF1KE1 ACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKN------
:: .:.::.:::.: . . . : ::::. .:.:: :...:::::: .::
NP_110 ACREGELSTCGCSRTARPK-DLPRDWLWGGCGDNVEYGYRFAKEFVDAREREKNFAKGSE
140 150 160 170 180 190
180 190 200 210 220 230
pF1KE1 --ARRLMNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYN
.: ::::.::::::... .. ::::::::::. :::: : .::.:: :::::.
NP_110 EQGRVLMNLQNNEAGRRAVYKMADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKYD
200 210 220 230 240 250
240 250 260 270 280 290
pF1KE1 AAVQVEVVRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRL
.:. ..:.: .::. . . .: ::::.. ::.:: .. .:::.::::::
NP_110 SAAAMRVTRKGRLELVN-------SRFTQPTPEDLVYVDPSPDYCLRNESTGSLGTQGRL
260 270 280 290 300
300 310 320 330 340
pF1KE1 CNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
::.:: : :::. :::::::: . ..: .:.:::::::::.:. :.: .. . ::
NP_110 CNKTSEGMDGCELMCCGRGYNQFKSVQVERCHCKFHWCCFVRCKKCTEIVDQYICK
310 320 330 340 350
>>XP_011539899 (OMIM: 158330,603490,611812) PREDICTED: p (373 aa)
initn: 1163 init1: 397 opt: 1190 Z-score: 1322.5 bits: 253.3 E(85289): 6.3e-67
Smith-Waterman score: 1190; 50.9% identity (74.4% similar) in 332 aa overlap (23-349:50-373)
10 20 30 40 50
pF1KE1 MHRNFRKWIFYVFLCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAIC
:. :::: ... . :.:. :: :: .:
XP_011 TQGKRNKRLPRTLPNQRGYEGEDTGHIPRYLAKLSSVGSISEEETCEKLKGLIQRQVQMC
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE1 QSRPDAIIVIGEGAQMGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITA
. ... . .:::..:.::::::: :::::.: :::. . :.:::::.:::..
XP_011 KRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAFVYAISS
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE1 AGVAHAVTAACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREI
:::: ::: :::.:.: .::::: .: : :..:.::: .. ::. ::. :::.::
XP_011 AGVAFAVTRACSSGELEKCGCDRTVHGVSPQ--GFQWSGCSDNIAYGVAFSQSFVDVRER
140 150 160 170 180 190
180 190 200 210 220
pF1KE1 KKNA---RRLMNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLK
.:.: : ::::::::::::.. .:..::::::::::: .:::: ..: ::.::: ::
XP_011 SKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALK
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE1 EKYNAAVQVEVVR--ASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSV
::...:..:: : .:: : : :.. . . ::::.: ::..::.: .: .
XP_011 EKFDGATEVEPRRVGSSRALVP---RNAQFKPHT---DEDLVYLEPSPDFCEQDMRSGVL
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE1 GTQGRLCNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFT
::.:: ::.:: . :::. .:::::..: : . .:.::::::::::: :.. .:. :
XP_011 GTRGRTCNKTSKAIDGCELLCCGRGFHTAQVELAERCSCKFHWCCFVKCRQCQRLVELHT
320 330 340 350 360 370
pF1KE1 CK
:.
XP_011 CR
349 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:01:24 2016 done: Sun Nov 6 12:01:25 2016
Total Scan time: 5.730 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]