Result of FASTA (omim) for
pFN21AE1820
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1820, 334 aa
1>>>pF1KE1820 334 - 334 aa - 334 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3879+/-0.000252; mu= 8.7661+/- 0.016
mean_var=146.2351+/-30.100, 0's: 0 Z-trim(125.2): 18 B-trim: 3040 in 2/55
Lambda= 0.106059
statistics sampled from 48547 (48570) to 48547 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.843), E-opt: 0.2 (0.569), width: 16
Scan time: 10.040
The best scores are: opt bits E(85289)
NP_619580 (OMIM: 610837) bcl-2-like protein 12 iso ( 334) 2341 368.7 9.7e-102
NP_001035758 (OMIM: 610837) bcl-2-like protein 12 ( 333) 2322 365.8 7.3e-101
NP_001269445 (OMIM: 610837) bcl-2-like protein 12 ( 243) 1616 257.7 1.9e-68
NP_001269448 (OMIM: 610837) bcl-2-like protein 12 ( 269) 1615 257.5 2.3e-68
XP_016882834 (OMIM: 610837) PREDICTED: bcl-2-like ( 242) 1597 254.8 1.4e-67
NP_001269449 (OMIM: 610837) bcl-2-like protein 12 ( 222) 1427 228.7 8.9e-60
NP_001269450 (OMIM: 610837) bcl-2-like protein 12 ( 193) 1240 200.1 3.3e-51
XP_016882835 (OMIM: 610837) PREDICTED: bcl-2-like ( 176) 884 145.6 7.6e-35
NP_001269446 (OMIM: 610837) bcl-2-like protein 12 ( 176) 884 145.6 7.6e-35
>>NP_619580 (OMIM: 610837) bcl-2-like protein 12 isoform (334 aa)
initn: 2341 init1: 2341 opt: 2341 Z-score: 1947.5 bits: 368.7 E(85289): 9.7e-102
Smith-Waterman score: 2341; 100.0% identity (100.0% similar) in 334 aa overlap (1-334:1-334)
10 20 30 40 50 60
pF1KE1 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQKLASDPALRSKLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQKLASDPALRSKLVR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LSSDSFARLVELFCSRDDSSRPSRACPGPPPPSPEPLARLALAMELSRRVAGLGGTLAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_619 LSSDSFARLVELFCSRDDSSRPSRACPGPPPPSPEPLARLALAMELSRRVAGLGGTLAGL
250 260 270 280 290 300
310 320 330
pF1KE1 SVEHVHSFTPWIQAHGGWEGILAVSPVDLNLPLD
::::::::::::::::::::::::::::::::::
NP_619 SVEHVHSFTPWIQAHGGWEGILAVSPVDLNLPLD
310 320 330
>>NP_001035758 (OMIM: 610837) bcl-2-like protein 12 isof (333 aa)
initn: 1464 init1: 1464 opt: 2322 Z-score: 1931.8 bits: 365.8 E(85289): 7.3e-101
Smith-Waterman score: 2322; 99.7% identity (99.7% similar) in 334 aa overlap (1-334:1-333)
10 20 30 40 50 60
pF1KE1 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPP-
70 80 90 100 110
130 140 150 160 170 180
pF1KE1 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQKLASDPALRSKLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQKLASDPALRSKLVR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 LSSDSFARLVELFCSRDDSSRPSRACPGPPPPSPEPLARLALAMELSRRVAGLGGTLAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSSDSFARLVELFCSRDDSSRPSRACPGPPPPSPEPLARLALAMELSRRVAGLGGTLAGL
240 250 260 270 280 290
310 320 330
pF1KE1 SVEHVHSFTPWIQAHGGWEGILAVSPVDLNLPLD
::::::::::::::::::::::::::::::::::
NP_001 SVEHVHSFTPWIQAHGGWEGILAVSPVDLNLPLD
300 310 320 330
>>NP_001269445 (OMIM: 610837) bcl-2-like protein 12 isof (243 aa)
initn: 1702 init1: 1614 opt: 1616 Z-score: 1349.9 bits: 257.7 E(85289): 1.9e-68
Smith-Waterman score: 1616; 97.9% identity (98.3% similar) in 235 aa overlap (1-232:1-235)
10 20 30 40 50 60
pF1KE1 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
130 140 150 160 170 180
190 200 210 220 230
pF1KE1 RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQK---LASDPALRSK
::::::::::::::::::::::::::::::::::::::::::::::: :: .:
NP_001 RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQKEGILAVSPVDLNL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 LVRLSSDSFARLVELFCSRDDSSRPSRACPGPPPPSPEPLARLALAMELSRRVAGLGGTL
NP_001 PLD
>>NP_001269448 (OMIM: 610837) bcl-2-like protein 12 isof (269 aa)
initn: 1664 init1: 1615 opt: 1615 Z-score: 1348.5 bits: 257.5 E(85289): 2.3e-68
Smith-Waterman score: 1615; 99.6% identity (100.0% similar) in 228 aa overlap (1-228:1-228)
10 20 30 40 50 60
pF1KE1 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQKLASDPALRSKLVR
:::::::::::::::::::::::::::::::::::::::::::::::.
NP_001 RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQKVMGICPTPWQGQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LSSDSFARLVELFCSRDDSSRPSRACPGPPPPSPEPLARLALAMELSRRVAGLGGTLAGL
NP_001 LRNGGHPGCFTRGLELAIGLSSFSEAATR
250 260
>>XP_016882834 (OMIM: 610837) PREDICTED: bcl-2-like prot (242 aa)
initn: 1053 init1: 881 opt: 1597 Z-score: 1334.2 bits: 254.8 E(85289): 1.4e-67
Smith-Waterman score: 1597; 97.4% identity (97.9% similar) in 235 aa overlap (1-232:1-234)
10 20 30 40 50 60
pF1KE1 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPP-
70 80 90 100 110
130 140 150 160 170 180
pF1KE1 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
120 130 140 150 160 170
190 200 210 220 230
pF1KE1 RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQK---LASDPALRSK
::::::::::::::::::::::::::::::::::::::::::::::: :: .:
XP_016 RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQKEGILAVSPVDLNL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 LVRLSSDSFARLVELFCSRDDSSRPSRACPGPPPPSPEPLARLALAMELSRRVAGLGGTL
XP_016 PLD
240
>>NP_001269449 (OMIM: 610837) bcl-2-like protein 12 isof (222 aa)
initn: 1427 init1: 1427 opt: 1427 Z-score: 1194.2 bits: 228.7 E(85289): 8.9e-60
Smith-Waterman score: 1427; 100.0% identity (100.0% similar) in 196 aa overlap (1-196:1-196)
10 20 30 40 50 60
pF1KE1 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQKLASDPALRSKLVR
::::::::::::::::
NP_001 RLEQLVQEQLKSPPSPGGHPGCFTRGLELAIGLSSFSEAATR
190 200 210 220
>>NP_001269450 (OMIM: 610837) bcl-2-like protein 12 isof (193 aa)
initn: 1240 init1: 1240 opt: 1240 Z-score: 1040.4 bits: 200.1 E(85289): 3.3e-51
Smith-Waterman score: 1240; 100.0% identity (100.0% similar) in 168 aa overlap (1-168:1-168)
10 20 30 40 50 60
pF1KE1 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGGHPGCFTRGLEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQKLASDPALRSKLVR
NP_001 AIGLSSFSEAATR
190
>>XP_016882835 (OMIM: 610837) PREDICTED: bcl-2-like prot (176 aa)
initn: 884 init1: 884 opt: 884 Z-score: 746.6 bits: 145.6 E(85289): 7.6e-35
Smith-Waterman score: 894; 81.4% identity (85.1% similar) in 161 aa overlap (1-161:1-148)
10 20 30 40 50 60
pF1KE1 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
:. ::: : .: :: . .:: . .:
XP_016 ------PS--YSRLL----C-FGGPAAGTAGPRAAEISAQPRITGSPIDREGSHTAEAGG
130 140 150 160
190 200 210 220 230 240
pF1KE1 RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQKLASDPALRSKLVR
XP_016 PAGGGGRSH
170
>>NP_001269446 (OMIM: 610837) bcl-2-like protein 12 isof (176 aa)
initn: 884 init1: 884 opt: 884 Z-score: 746.6 bits: 145.6 E(85289): 7.6e-35
Smith-Waterman score: 894; 81.4% identity (85.1% similar) in 161 aa overlap (1-161:1-148)
10 20 30 40 50 60
pF1KE1 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ
:. ::: : .: :: . .:: . .:
NP_001 ------PS--YSRLL----C-FGGPAAGTAGPRAAEISAQPRITGSPIDREGSHTAEAGG
130 140 150 160
190 200 210 220 230 240
pF1KE1 RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQKLASDPALRSKLVR
NP_001 PAGGGGRSH
170
334 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:16:39 2016 done: Sun Nov 6 13:16:40 2016
Total Scan time: 10.040 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]