FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1781, 289 aa
  1>>>pF1KE1781 289 - 289 aa - 289 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1153+/-0.000362; mu= 16.5302+/- 0.022
 mean_var=64.3681+/-13.507, 0's: 0 Z-trim(113.6): 2  B-trim: 1227 in 1/54
 Lambda= 0.159860
 statistics sampled from 23062 (23064) to 23062 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.27), width:  16
 Scan time:  6.950

The best scores are:                                      opt bits E(85289)
NP_000261 (OMIM: 164050,613179) purine nucleoside  ( 289) 1953 459.0 4.8e-129
NP_002442 (OMIM: 156540) S-methyl-5'-thioadenosine ( 283)  274 71.8 1.7e-12


>>NP_000261 (OMIM: 164050,613179) purine nucleoside phos  (289 aa)
 initn: 1953 init1: 1953 opt: 1953  Z-score: 2437.7  bits: 459.0 E(85289): 4.8e-129
Smith-Waterman score: 1953; 100.0% identity (100.0% similar) in 289 aa overlap (1-289:1-289)

               10        20        30        40        50        60
pF1KE1 MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL
              190       200       210       220       230       240

              250       260       270       280         
pF1KE1 ITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS
              250       260       270       280         

>>NP_002442 (OMIM: 156540) S-methyl-5'-thioadenosine pho  (283 aa)
 initn: 181 init1: 137 opt: 274  Z-score: 345.1  bits: 71.8 E(85289): 1.7e-12
Smith-Waterman score: 274; 27.5% identity (58.8% similar) in 262 aa overlap (26-283:11-256)

               10        20        30        40        50        60
pF1KE1 MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST
                                ...:: :.::     .. ...   : . : : .  
NP_002                MASGTTTTAVKIGIIGGTGLD--DPEILEGRTEKYVDTP-FGK--
                              10        20          30         40  

               70        80          90       100         110      
pF1KE1 VPGHAGRLVFGFLNGRACVMM--QGRFHMYEGYPLWKVTFPVRVFHLL--GVDTLVVTNA
        :. :  :..: ...  ::..  .:: :    .:  ::.. . .. :   :   ..::.:
NP_002 -PSDA--LILGKIKNVDCVLLARHGRQHTI--MPS-KVNYQANIWALKEEGCTHVIVTTA
                  50        60          70         80        90    

        120       130       140       150       160       170      
pF1KE1 AGGLNPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALS
        :.:  ... :::..: . :.   .  :.   : ..   :     :.. .    :.  . 
NP_002 CGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIE
          100       110       120       130       140       150    

        180       190       200       210       220       230      
pF1KE1 TWKQMGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVF
       : :..:  :  ..::.: . :: : . ::  ...  :::...:.:::::..:.. :.   
NP_002 TAKKLG-LRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYA
          160        170       180       190       200       210   

        240       250       260       270       280                
pF1KE1 GFSLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS       
       .... :.      :  : .. ..:: . :. :.: .   :.:...::             
NP_002 SIAMATDYDCWK-EHEEAVSVDRVLKTLKENANKAK---SLLLTTIPQIGSTEWSETLHN
           220        230       240          250       260         

NP_002 LKNMAQFSVLLPRH
     270       280   




289 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 09:51:45 2016 done: Sun Nov  6 09:51:46 2016
 Total Scan time:  6.950 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]