Result of FASTA (omim) for
pFN21AE1778
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1778, 285 aa
1>>>pF1KE1778 285 - 285 aa - 285 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4122+/-0.000416; mu= 14.0206+/- 0.026
mean_var=59.7106+/-12.081, 0's: 0 Z-trim(110.8): 52 B-trim: 862 in 2/49
Lambda= 0.165977
statistics sampled from 19187 (19223) to 19187 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.225), width: 16
Scan time: 6.690
The best scores are: opt bits E(85289)
XP_016856949 (OMIM: 611075) PREDICTED: diphthine m ( 285) 1851 451.8 6.7e-127
NP_057042 (OMIM: 611075) diphthine methyl ester sy ( 285) 1851 451.8 6.7e-127
NP_001070862 (OMIM: 611075) diphthine methyl ester ( 285) 1851 451.8 6.7e-127
NP_001070863 (OMIM: 611075) diphthine methyl ester ( 284) 1834 447.8 1.1e-125
XP_011539871 (OMIM: 611075) PREDICTED: diphthine m ( 239) 1149 283.7 2.3e-76
XP_005270995 (OMIM: 611075) PREDICTED: diphthine m ( 240) 1147 283.2 3.2e-76
XP_005270996 (OMIM: 611075) PREDICTED: diphthine m ( 172) 1143 282.2 4.6e-76
XP_016856950 (OMIM: 611075) PREDICTED: diphthine m ( 172) 1143 282.2 4.6e-76
XP_011539872 (OMIM: 611075) PREDICTED: diphthine m ( 172) 1143 282.2 4.6e-76
XP_006710746 (OMIM: 611075) PREDICTED: diphthine m ( 164) 974 241.8 6.7e-64
XP_005270998 (OMIM: 611075) PREDICTED: diphthine m ( 164) 974 241.8 6.7e-64
XP_016856951 (OMIM: 611075) PREDICTED: diphthine m ( 163) 957 237.7 1.1e-62
>>XP_016856949 (OMIM: 611075) PREDICTED: diphthine methy (285 aa)
initn: 1851 init1: 1851 opt: 1851 Z-score: 2399.3 bits: 451.8 E(85289): 6.7e-127
Smith-Waterman score: 1851; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KE1 MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM
190 200 210 220 230 240
250 260 270 280
pF1KE1 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
250 260 270 280
>>NP_057042 (OMIM: 611075) diphthine methyl ester syntha (285 aa)
initn: 1851 init1: 1851 opt: 1851 Z-score: 2399.3 bits: 451.8 E(85289): 6.7e-127
Smith-Waterman score: 1851; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KE1 MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM
190 200 210 220 230 240
250 260 270 280
pF1KE1 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
:::::::::::::::::::::::::::::::::::::::::::::
NP_057 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
250 260 270 280
>>NP_001070862 (OMIM: 611075) diphthine methyl ester syn (285 aa)
initn: 1851 init1: 1851 opt: 1851 Z-score: 2399.3 bits: 451.8 E(85289): 6.7e-127
Smith-Waterman score: 1851; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KE1 MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM
190 200 210 220 230 240
250 260 270 280
pF1KE1 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
250 260 270 280
>>NP_001070863 (OMIM: 611075) diphthine methyl ester syn (284 aa)
initn: 1382 init1: 1382 opt: 1834 Z-score: 2377.3 bits: 447.8 E(85289): 1.1e-125
Smith-Waterman score: 1834; 99.6% identity (99.6% similar) in 285 aa overlap (1-285:1-284)
10 20 30 40 50 60
pF1KE1 MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_001 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEP-VTEETLCVGLARVGADDQKIAAGTLRQM
190 200 210 220 230
250 260 270 280
pF1KE1 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
240 250 260 270 280
>>XP_011539871 (OMIM: 611075) PREDICTED: diphthine methy (239 aa)
initn: 1149 init1: 1149 opt: 1149 Z-score: 1492.1 bits: 283.7 E(85289): 2.3e-76
Smith-Waterman score: 1149; 98.9% identity (99.4% similar) in 179 aa overlap (1-179:1-179)
10 20 30 40 50 60
pF1KE1 MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::. :
XP_011 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLINYRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM
XP_011 DTLCWLSQGWSRRPENCSRHFKANVHCGLGRTIAFLDHHRRQHTSNGDGDAKSVFHTRK
190 200 210 220 230
>>XP_005270995 (OMIM: 611075) PREDICTED: diphthine methy (240 aa)
initn: 1147 init1: 1147 opt: 1147 Z-score: 1489.4 bits: 283.2 E(85289): 3.2e-76
Smith-Waterman score: 1147; 97.8% identity (99.4% similar) in 180 aa overlap (1-180:1-180)
10 20 30 40 50 60
pF1KE1 MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.. .
XP_005 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLINSYR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM
XP_005 GDTLCWLSQGWSRRPENCSRHFKANVHCGLGRTIAFLDHHRRQHTSNGDGDAKSVFHTRK
190 200 210 220 230 240
>>XP_005270996 (OMIM: 611075) PREDICTED: diphthine methy (172 aa)
initn: 1143 init1: 1143 opt: 1143 Z-score: 1486.6 bits: 282.2 E(85289): 4.6e-76
Smith-Waterman score: 1143; 100.0% identity (100.0% similar) in 172 aa overlap (114-285:1-172)
90 100 110 120 130 140
pF1KE1 DPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCCGLQLYKFGETVSIVFWTDTWRPE
::::::::::::::::::::::::::::::
XP_005 MNAVGCCGLQLYKFGETVSIVFWTDTWRPE
10 20 30
150 160 170 180 190 200
pF1KE1 SFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQN
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE1 QRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQMCTVDLGEPLHSLIITGGSIHPME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQMCTVDLGEPLHSLIITGGSIHPME
100 110 120 130 140 150
270 280
pF1KE1 MEMLSLFSIPENSSESQSINGL
::::::::::::::::::::::
XP_005 MEMLSLFSIPENSSESQSINGL
160 170
>>XP_016856950 (OMIM: 611075) PREDICTED: diphthine methy (172 aa)
initn: 1143 init1: 1143 opt: 1143 Z-score: 1486.6 bits: 282.2 E(85289): 4.6e-76
Smith-Waterman score: 1143; 100.0% identity (100.0% similar) in 172 aa overlap (114-285:1-172)
90 100 110 120 130 140
pF1KE1 DPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCCGLQLYKFGETVSIVFWTDTWRPE
::::::::::::::::::::::::::::::
XP_016 MNAVGCCGLQLYKFGETVSIVFWTDTWRPE
10 20 30
150 160 170 180 190 200
pF1KE1 SFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQN
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE1 QRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQMCTVDLGEPLHSLIITGGSIHPME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQMCTVDLGEPLHSLIITGGSIHPME
100 110 120 130 140 150
270 280
pF1KE1 MEMLSLFSIPENSSESQSINGL
::::::::::::::::::::::
XP_016 MEMLSLFSIPENSSESQSINGL
160 170
>>XP_011539872 (OMIM: 611075) PREDICTED: diphthine methy (172 aa)
initn: 1143 init1: 1143 opt: 1143 Z-score: 1486.6 bits: 282.2 E(85289): 4.6e-76
Smith-Waterman score: 1143; 100.0% identity (100.0% similar) in 172 aa overlap (114-285:1-172)
90 100 110 120 130 140
pF1KE1 DPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCCGLQLYKFGETVSIVFWTDTWRPE
::::::::::::::::::::::::::::::
XP_011 MNAVGCCGLQLYKFGETVSIVFWTDTWRPE
10 20 30
150 160 170 180 190 200
pF1KE1 SFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQN
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE1 QRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQMCTVDLGEPLHSLIITGGSIHPME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQMCTVDLGEPLHSLIITGGSIHPME
100 110 120 130 140 150
270 280
pF1KE1 MEMLSLFSIPENSSESQSINGL
::::::::::::::::::::::
XP_011 MEMLSLFSIPENSSESQSINGL
160 170
>>XP_006710746 (OMIM: 611075) PREDICTED: diphthine methy (164 aa)
initn: 974 init1: 974 opt: 974 Z-score: 1268.2 bits: 241.8 E(85289): 6.7e-64
Smith-Waterman score: 974; 97.4% identity (98.7% similar) in 153 aa overlap (133-285:12-164)
110 120 130 140 150 160
pF1KE1 IPYRVIHNASIMNAVGCCGLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCL
.:. :::::::::::::::::::::::::
XP_006 MLISVMLHSLWLVIHLDTWRPESFFDKVKKNRQNGMHTLCL
10 20 30 40
170 180 190 200 210 220
pF1KE1 LDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGL
50 60 70 80 90 100
230 240 250 260 270 280
pF1KE1 ARVGADDQKIAAGTLRQMCTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARVGADDQKIAAGTLRQMCTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSI
110 120 130 140 150 160
pF1KE1 NGL
:::
XP_006 NGL
285 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 11:10:34 2016 done: Sun Nov 6 11:10:35 2016
Total Scan time: 6.690 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]