Result of FASTA (omim) for
pFN21AE1764
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1764, 270 aa
1>>>pF1KE1764 270 - 270 aa - 270 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0715+/-0.000288; mu= 11.8792+/- 0.018
mean_var=82.4291+/-16.547, 0's: 0 Z-trim(119.5): 5 B-trim: 1611 in 1/55
Lambda= 0.141265
statistics sampled from 33499 (33504) to 33499 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.393), width: 16
Scan time: 6.840
The best scores are: opt bits E(85289)
XP_005253966 (OMIM: 602740) PREDICTED: 5'-AMP-acti ( 270) 1855 387.0 1.9e-107
NP_006244 (OMIM: 602740) 5'-AMP-activated protein ( 270) 1855 387.0 1.9e-107
NP_005390 (OMIM: 602741) 5'-AMP-activated protein ( 272) 1298 273.5 2.9e-73
XP_011508031 (OMIM: 602741) PREDICTED: 5'-AMP-acti ( 265) 1148 242.9 4.5e-64
XP_016857186 (OMIM: 602741) PREDICTED: 5'-AMP-acti ( 197) 581 127.3 2.1e-29
>>XP_005253966 (OMIM: 602740) PREDICTED: 5'-AMP-activate (270 aa)
initn: 1855 init1: 1855 opt: 1855 Z-score: 2049.9 bits: 387.0 E(85289): 1.9e-107
Smith-Waterman score: 1855; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270)
10 20 30 40 50 60
pF1KE1 MGNTSSERAALERHGGHKTPRRDSSGGTKDGDRPKILMDSPEDADLFHSEEIKAPEKEEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGNTSSERAALERHGGHKTPRRDSSGGTKDGDRPKILMDSPEDADLFHSEEIKAPEKEEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LAWQHDLEVNDKAPAQARPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAILDLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAWQHDLEVNDKAPAQARPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAILDLPE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SSPPGPYHQEPYVCKPEERFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSPPGPYHQEPYVCKPEERFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLY
190 200 210 220 230 240
250 260 270
pF1KE1 ALSIKDGVMVLSATHRYKKKYVTTLLYKPI
::::::::::::::::::::::::::::::
XP_005 ALSIKDGVMVLSATHRYKKKYVTTLLYKPI
250 260 270
>>NP_006244 (OMIM: 602740) 5'-AMP-activated protein kina (270 aa)
initn: 1855 init1: 1855 opt: 1855 Z-score: 2049.9 bits: 387.0 E(85289): 1.9e-107
Smith-Waterman score: 1855; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270)
10 20 30 40 50 60
pF1KE1 MGNTSSERAALERHGGHKTPRRDSSGGTKDGDRPKILMDSPEDADLFHSEEIKAPEKEEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MGNTSSERAALERHGGHKTPRRDSSGGTKDGDRPKILMDSPEDADLFHSEEIKAPEKEEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LAWQHDLEVNDKAPAQARPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAILDLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LAWQHDLEVNDKAPAQARPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAILDLPE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SSPPGPYHQEPYVCKPEERFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SSPPGPYHQEPYVCKPEERFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLY
190 200 210 220 230 240
250 260 270
pF1KE1 ALSIKDGVMVLSATHRYKKKYVTTLLYKPI
::::::::::::::::::::::::::::::
NP_006 ALSIKDGVMVLSATHRYKKKYVTTLLYKPI
250 260 270
>>NP_005390 (OMIM: 602741) 5'-AMP-activated protein kina (272 aa)
initn: 1276 init1: 555 opt: 1298 Z-score: 1436.4 bits: 273.5 E(85289): 2.9e-73
Smith-Waterman score: 1298; 70.3% identity (87.2% similar) in 273 aa overlap (1-270:1-272)
10 20 30 40 50 60
pF1KE1 MGNTSSERAALERHGGHKTPRRDSSGGTKDGDRPKILMDSPEDADLFHSEEIKAPEKEEF
::::.:.:.. ::::. :. : ...:: : . ::.. : .: ..: . : : .::
NP_005 MGNTTSDRVSGERHGA-KAARSEGAGGHAPGKEHKIMVGSTDDPSVFSLPDSKLPGDKEF
10 20 30 40 50
70 80 90 100 110
pF1KE1 LAWQHDLEVNDKAPAQARPTVFRWTGGGKEVYLSGSFNNWS-KLPLTRSHNNFVAILDLP
..::.::: . : ::::::.::. :::::..:::::::: :.:: .:::.::::::::
NP_005 VSWQQDLEDSVKPTQQARPTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAILDLP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 EGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVS--
::::::::::::::.::::::.:::::::.::.:.:::.:::::::: .::.. :..:
NP_005 EGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSDFEVFDALKLDSMESSETSCR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 ELSSSPPGPYHQEPYVCKPEERFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLN
.::::::::: :: :. . ::::..:::::::::::::::::.:::::::::::::::::
NP_005 DLSSSPPGPYGQEMYAFRSEERFKSPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLN
180 190 200 210 220 230
240 250 260 270
pF1KE1 HLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI
:::::::::.:::::::::::::::::::::::
NP_005 HLYALSIKDSVMVLSATHRYKKKYVTTLLYKPI
240 250 260 270
>>XP_011508031 (OMIM: 602741) PREDICTED: 5'-AMP-activate (265 aa)
initn: 1126 init1: 458 opt: 1148 Z-score: 1271.3 bits: 242.9 E(85289): 4.5e-64
Smith-Waterman score: 1148; 67.7% identity (85.9% similar) in 248 aa overlap (1-245:1-247)
10 20 30 40 50 60
pF1KE1 MGNTSSERAALERHGGHKTPRRDSSGGTKDGDRPKILMDSPEDADLFHSEEIKAPEKEEF
::::.:.:.. ::::. :. : ...:: : . ::.. : .: ..: . : : .::
XP_011 MGNTTSDRVSGERHGA-KAARSEGAGGHAPGKEHKIMVGSTDDPSVFSLPDSKLPGDKEF
10 20 30 40 50
70 80 90 100 110
pF1KE1 LAWQHDLEVNDKAPAQARPTVFRWTGGGKEVYLSGSFNNWS-KLPLTRSHNNFVAILDLP
..::.::: . : ::::::.::. :::::..:::::::: :.:: .:::.::::::::
XP_011 VSWQQDLEDSVKPTQQARPTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAILDLP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 EGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVS--
::::::::::::::.::::::.:::::::.::.:.:::.:::::::: .::.. :..:
XP_011 EGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSDFEVFDALKLDSMESSETSCR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 ELSSSPPGPYHQEPYVCKPEERFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLN
.::::::::: :: :. . ::::..:::::::::::::::::.:::::::::::::::::
XP_011 DLSSSPPGPYGQEMYAFRSEERFKSPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLN
180 190 200 210 220 230
240 250 260 270
pF1KE1 HLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI
::::::::
XP_011 HLYALSIKIKKLRLREGQIARQCDGP
240 250 260
>>XP_016857186 (OMIM: 602741) PREDICTED: 5'-AMP-activate (197 aa)
initn: 291 init1: 291 opt: 581 Z-score: 648.8 bits: 127.3 E(85289): 2.1e-29
Smith-Waterman score: 581; 60.0% identity (80.7% similar) in 140 aa overlap (1-139:1-139)
10 20 30 40 50 60
pF1KE1 MGNTSSERAALERHGGHKTPRRDSSGGTKDGDRPKILMDSPEDADLFHSEEIKAPEKEEF
::::.:.:.. ::::. :. : ...:: : . ::.. : .: ..: . : : .::
XP_016 MGNTTSDRVSGERHGA-KAARSEGAGGHAPGKEHKIMVGSTDDPSVFSLPDSKLPGDKEF
10 20 30 40 50
70 80 90 100 110
pF1KE1 LAWQHDLEVNDKAPAQARPTVFRWTGGGKEVYLSGSFNNWS-KLPLTRSHNNFVAILDLP
..::.::: . : ::::::.::. :::::..:::::::: :.:: .:::.::::::::
XP_016 VSWQQDLEDSVKPTQQARPTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAILDLP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 EGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSEL
::::::::::::::.:::::
XP_016 EGEHQYKFFVDGQWVHDPSETFPAHPQGLMVKKCMRFDLRKDSNPHPSFLLIYFKLFLTK
120 130 140 150 160 170
270 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:41:58 2016 done: Sun Nov 6 14:41:59 2016
Total Scan time: 6.840 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]