Result of FASTA (omim) for
pFN21AE1749
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1749, 252 aa
1>>>pF1KE1749 252 - 252 aa - 252 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4331+/-0.000298; mu= 14.9274+/- 0.019
mean_var=89.3475+/-18.149, 0's: 0 Z-trim(118.9): 173 B-trim: 402 in 1/53
Lambda= 0.135685
statistics sampled from 32116 (32324) to 32116 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.379), width: 16
Scan time: 6.750
The best scores are: opt bits E(85289)
XP_005273311 (OMIM: 120831) PREDICTED: C4b-binding ( 252) 1796 361.0 1.2e-99
NP_000707 (OMIM: 120831) C4b-binding protein beta ( 252) 1796 361.0 1.2e-99
NP_001017365 (OMIM: 120831) C4b-binding protein be ( 252) 1796 361.0 1.2e-99
NP_001017367 (OMIM: 120831) C4b-binding protein be ( 252) 1796 361.0 1.2e-99
NP_001017366 (OMIM: 120831) C4b-binding protein be ( 251) 1779 357.6 1.2e-98
NP_001017364 (OMIM: 120831) C4b-binding protein be ( 251) 1779 357.6 1.2e-98
XP_005273312 (OMIM: 120831) PREDICTED: C4b-binding ( 227) 982 201.6 1e-51
XP_011533056 (OMIM: 608397) PREDICTED: CUB and sus (2238) 455 99.3 6.3e-20
XP_011533055 (OMIM: 608397) PREDICTED: CUB and sus (2595) 455 99.3 7e-20
XP_016869220 (OMIM: 608397) PREDICTED: CUB and sus (3327) 455 99.4 8.4e-20
XP_011533054 (OMIM: 608397) PREDICTED: CUB and sus (3549) 455 99.5 8.8e-20
NP_150094 (OMIM: 608397) CUB and sushi domain-cont (3564) 455 99.5 8.8e-20
XP_016855679 (OMIM: 608398) PREDICTED: CUB and sus (3362) 393 87.3 3.8e-16
XP_016855678 (OMIM: 608398) PREDICTED: CUB and sus (3506) 393 87.3 3.9e-16
XP_016855683 (OMIM: 608398) PREDICTED: CUB and sus (3566) 393 87.3 4e-16
XP_016855677 (OMIM: 608398) PREDICTED: CUB and sus (3567) 393 87.3 4e-16
XP_016855676 (OMIM: 608398) PREDICTED: CUB and sus (3606) 393 87.3 4e-16
XP_016855674 (OMIM: 608398) PREDICTED: CUB and sus (3607) 393 87.3 4e-16
XP_016855675 (OMIM: 608398) PREDICTED: CUB and sus (3607) 393 87.3 4e-16
XP_011515117 (OMIM: 608399) PREDICTED: CUB and sus (2173) 375 83.6 3.2e-15
XP_016868501 (OMIM: 608399) PREDICTED: CUB and sus (3463) 375 83.8 4.5e-15
XP_016868500 (OMIM: 608399) PREDICTED: CUB and sus (3507) 375 83.8 4.5e-15
NP_443132 (OMIM: 608399) CUB and sushi domain-cont (3538) 375 83.8 4.5e-15
XP_016868499 (OMIM: 608399) PREDICTED: CUB and sus (3577) 375 83.8 4.6e-15
XP_011515118 (OMIM: 608399) PREDICTED: CUB and sus (3603) 375 83.8 4.6e-15
XP_016868498 (OMIM: 608399) PREDICTED: CUB and sus (3637) 375 83.8 4.6e-15
NP_937757 (OMIM: 608399) CUB and sushi domain-cont (3667) 375 83.8 4.7e-15
XP_016868497 (OMIM: 608399) PREDICTED: CUB and sus (3681) 375 83.8 4.7e-15
NP_937756 (OMIM: 608399) CUB and sushi domain-cont (3707) 375 83.8 4.7e-15
NP_443128 (OMIM: 608398) CUB and sushi domain-cont (3487) 371 83.0 7.7e-15
NP_699197 (OMIM: 611691) sushi, von Willebrand fac (3571) 344 77.7 3.1e-13
XP_005245497 (OMIM: 147050,173610) PREDICTED: P-se ( 768) 298 68.1 5.1e-11
NP_001268885 (OMIM: 608398) CUB and sushi domain-c (3631) 305 70.1 6.2e-11
NP_001701 (OMIM: 138470,612924,615489,615561) comp ( 764) 292 67.0 1.1e-10
XP_011507508 (OMIM: 120650,240500,610927,614699) P ( 969) 280 64.7 6.9e-10
NP_001006659 (OMIM: 120650,240500,610927,614699) c (1092) 280 64.8 7.6e-10
NP_000564 (OMIM: 120620,607486,611162) complement (2039) 277 64.4 1.8e-09
XP_006711229 (OMIM: 120620,607486,611162) PREDICTE (2459) 277 64.5 2.1e-09
NP_000642 (OMIM: 120620,607486,611162) complement (2489) 277 64.5 2.1e-09
XP_011507507 (OMIM: 120620,607486,611162) PREDICTE (2554) 277 64.5 2.1e-09
XP_005273308 (OMIM: 120830) PREDICTED: C4b-binding ( 597) 267 62.0 2.8e-09
XP_005273309 (OMIM: 120830) PREDICTED: C4b-binding ( 597) 267 62.0 2.8e-09
NP_000706 (OMIM: 120830) C4b-binding protein alpha ( 597) 267 62.0 2.8e-09
NP_000033 (OMIM: 138700) beta-2-glycoprotein 1 pre ( 345) 261 60.6 4.3e-09
NP_000441 (OMIM: 131210,145500) E-selectin precurs ( 610) 263 61.2 4.9e-09
NP_110414 (OMIM: 608593,614809) complement factor ( 569) 253 59.2 1.8e-08
XP_011508322 (OMIM: 608593,614809) PREDICTED: comp ( 572) 253 59.2 1.8e-08
NP_001868 (OMIM: 120650,240500,610927,614699) comp (1033) 255 59.8 2.2e-08
XP_011507588 (OMIM: 134580,613235) PREDICTED: coag ( 628) 246 57.9 5.1e-08
NP_001985 (OMIM: 134580,613235) coagulation factor ( 661) 246 57.9 5.3e-08
>>XP_005273311 (OMIM: 120831) PREDICTED: C4b-binding pro (252 aa)
initn: 1796 init1: 1796 opt: 1796 Z-score: 1910.0 bits: 361.0 E(85289): 1.2e-99
Smith-Waterman score: 1796; 100.0% identity (100.0% similar) in 252 aa overlap (1-252:1-252)
10 20 30 40 50 60
pF1KE1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
190 200 210 220 230 240
250
pF1KE1 ELKKAELKAKLL
::::::::::::
XP_005 ELKKAELKAKLL
250
>>NP_000707 (OMIM: 120831) C4b-binding protein beta chai (252 aa)
initn: 1796 init1: 1796 opt: 1796 Z-score: 1910.0 bits: 361.0 E(85289): 1.2e-99
Smith-Waterman score: 1796; 100.0% identity (100.0% similar) in 252 aa overlap (1-252:1-252)
10 20 30 40 50 60
pF1KE1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
190 200 210 220 230 240
250
pF1KE1 ELKKAELKAKLL
::::::::::::
NP_000 ELKKAELKAKLL
250
>>NP_001017365 (OMIM: 120831) C4b-binding protein beta c (252 aa)
initn: 1796 init1: 1796 opt: 1796 Z-score: 1910.0 bits: 361.0 E(85289): 1.2e-99
Smith-Waterman score: 1796; 100.0% identity (100.0% similar) in 252 aa overlap (1-252:1-252)
10 20 30 40 50 60
pF1KE1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
190 200 210 220 230 240
250
pF1KE1 ELKKAELKAKLL
::::::::::::
NP_001 ELKKAELKAKLL
250
>>NP_001017367 (OMIM: 120831) C4b-binding protein beta c (252 aa)
initn: 1796 init1: 1796 opt: 1796 Z-score: 1910.0 bits: 361.0 E(85289): 1.2e-99
Smith-Waterman score: 1796; 100.0% identity (100.0% similar) in 252 aa overlap (1-252:1-252)
10 20 30 40 50 60
pF1KE1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
190 200 210 220 230 240
250
pF1KE1 ELKKAELKAKLL
::::::::::::
NP_001 ELKKAELKAKLL
250
>>NP_001017366 (OMIM: 120831) C4b-binding protein beta c (251 aa)
initn: 1777 init1: 1637 opt: 1779 Z-score: 1892.1 bits: 357.6 E(85289): 1.2e-98
Smith-Waterman score: 1779; 99.6% identity (99.6% similar) in 252 aa overlap (1-252:1-251)
10 20 30 40 50 60
pF1KE1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 MFFWCACCLMVAWRVSASD-EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
180 190 200 210 220 230
250
pF1KE1 ELKKAELKAKLL
::::::::::::
NP_001 ELKKAELKAKLL
240 250
>>NP_001017364 (OMIM: 120831) C4b-binding protein beta c (251 aa)
initn: 1777 init1: 1637 opt: 1779 Z-score: 1892.1 bits: 357.6 E(85289): 1.2e-98
Smith-Waterman score: 1779; 99.6% identity (99.6% similar) in 252 aa overlap (1-252:1-251)
10 20 30 40 50 60
pF1KE1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 MFFWCACCLMVAWRVSASD-EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
180 190 200 210 220 230
250
pF1KE1 ELKKAELKAKLL
::::::::::::
NP_001 ELKKAELKAKLL
240 250
>>XP_005273312 (OMIM: 120831) PREDICTED: C4b-binding pro (227 aa)
initn: 1001 init1: 840 opt: 982 Z-score: 1049.5 bits: 201.6 E(85289): 1e-51
Smith-Waterman score: 982; 99.3% identity (99.3% similar) in 136 aa overlap (1-136:1-135)
10 20 30 40 50 60
pF1KE1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_005 MFFWCACCLMVAWRVSASD-EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
::::::::::::::::
XP_005 CLEDHTWAPPFPICKSIPQTRPLPFQPCSPLFLFLLRQSLALFPRLECSGRILAHCNLHL
120 130 140 150 160 170
>>XP_011533056 (OMIM: 608397) PREDICTED: CUB and sushi d (2238 aa)
initn: 435 init1: 351 opt: 455 Z-score: 478.8 bits: 99.3 E(85289): 6.3e-20
Smith-Waterman score: 455; 35.3% identity (64.7% similar) in 204 aa overlap (26-226:1301-1498)
10 20 30 40 50
pF1KE1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHL
.:: :.: . : : . ..: :: :
XP_011 WRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLT-VYGAT-AIFTCNTGYTL
1280 1290 1300 1310 1320
60 70 80 90 100 110
pF1KE1 VGKKTLFCNASKEWDNTTTECRLGHC--PDPVLVNGEFSSSGPVNVSDKITFMCNDHYIL
::... : :. :... :.: ::: :::. :::..:..: . : ....:: . :
XP_011 VGSHVRECLANGLWSGSETRCLAGHCGSPDPI-VNGHISGDG-FSYRDTVVYQCNPGFRL
1330 1340 1350 1360 1370 1380
120 130 140 150 160 170
pF1KE1 KGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVG
:.. ::.:: :. :.: : ::::.::. .:..:.:...... :. : : :
XP_011 VGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQG
1390 1400 1410 1420 1430 1440
180 190 200 210 220 230
pF1KE1 VQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMT
:.. :: .:.::: ::.:.... . :.:. :. :. :..: :. :
XP_011 VSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQ--NFPESFEYGMSILYHCKKG
1450 1460 1470 1480 1490 1500
240 250
pF1KE1 MEELKYSLELKKAELKAKLL
XP_011 FYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSES
1510 1520 1530 1540 1550 1560
>--
initn: 380 init1: 193 opt: 292 Z-score: 306.4 bits: 67.4 E(85289): 2.5e-10
Smith-Waterman score: 292; 27.0% identity (55.7% similar) in 185 aa overlap (23-201:1771-1953)
10 20 30 40 50
pF1KE1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKG
::. :::.:. ... . .: :. :
XP_011 YVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDG
1750 1760 1770 1780 1790 1800
60 70 80 90 100 110
pF1KE1 YHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITFMCNDHY
:.: . : :.. : . .: : :: . ..:..:... . .... :.:.. .
XP_011 YQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKS-FTYKSEVFFQCKSPF
1810 1820 1830 1840 1850
120 130 140 150 160
pF1KE1 ILKGSNRSQCLEDHTWAPPFPIC---KSRDCDPPGNPVHGYFEGN-NFTLGSTISYYCED
:: ::.: : : ::. : : : ::.: : ... .. .:::. . :.
XP_011 ILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRK
1860 1870 1880 1890 1900 1910
170 180 190 200 210 220
pF1KE1 RYYLVGVQEQQCVDG-EWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQL
:.. : . :. . ::. : . . .::
XP_011 GYHIQGSTTRTCLANLTWSGIQTEC-IPHACRQPETPAHADVRAIDLPTFGYTLVYTCHP
1920 1930 1940 1950 1960 1970
230 240 250
pF1KE1 KESGMTMEELKYSLELKKAELKAKLL
XP_011 GFFLAGGSEHRTCKADMKWTGKSPVCKSKGVREVNETVTKTPVPSDVFFVNSLWKGYYEY
1980 1990 2000 2010 2020 2030
>--
initn: 420 init1: 171 opt: 271 Z-score: 284.1 bits: 63.3 E(85289): 4.4e-09
Smith-Waterman score: 271; 28.3% identity (55.3% similar) in 152 aa overlap (47-194:1618-1769)
20 30 40 50 60 70
pF1KE1 ASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC
. : :..: :. : . :.. :
XP_011 GNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVC
1590 1600 1610 1620 1630 1640
80 90 100 110 120 130
pF1KE1 RLGHCPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICK
. : .: . .:: . :: . :... . : . : .: .: . ::. : :
XP_011 EAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCT
1650 1660 1670 1680 1690 1700
140 150 160 170 180 190
pF1KE1 SRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQ--QCV-DGEWSSALPVCK
.: ::. ..: :..::...:.:: :. : . .: .:. ::.:. . ::::
XP_011 IISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCK
1710 1720 1730 1740 1750 1760
200 210 220 230 240 250
pF1KE1 LIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLELKKAELKAKLL
.
XP_011 AVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV
1770 1780 1790 1800 1810 1820
>--
initn: 243 init1: 128 opt: 206 Z-score: 215.4 bits: 50.5 E(85289): 2.9e-05
Smith-Waterman score: 222; 29.3% identity (52.0% similar) in 123 aa overlap (47-161:1499-1616)
20 30 40 50 60 70
pF1KE1 ASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC
: : ::..:.:...: : :. :: . .:
XP_011 NCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKC
1470 1480 1490 1500 1510 1520
80 90 100 110 120 130
pF1KE1 RLGHCPDP-----VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPF
: : ....::. . : : . . : : :.. : :: :. .
XP_011 LAISCGHPGVPANAVLTGELFTYGAV-----VHYSCRGSESLIGNDTRVCQEDSHWSGAL
1530 1540 1550 1560 1570 1580
140 150 160 170 180
pF1KE1 PICKSRD---CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSAL
: : . . : ::.:.:: :..: : .
XP_011 PHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGL
1590 1600 1610 1620 1630 1640
190 200 210 220 230 240
pF1KE1 PVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLELKKAELK
XP_011 QPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTA
1650 1660 1670 1680 1690 1700
>>XP_011533055 (OMIM: 608397) PREDICTED: CUB and sushi d (2595 aa)
initn: 435 init1: 351 opt: 455 Z-score: 477.9 bits: 99.3 E(85289): 7e-20
Smith-Waterman score: 455; 35.3% identity (64.7% similar) in 204 aa overlap (26-226:1658-1855)
10 20 30 40 50
pF1KE1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHL
.:: :.: . : : . ..: :: :
XP_011 WRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLT-VYGAT-AIFTCNTGYTL
1630 1640 1650 1660 1670 1680
60 70 80 90 100 110
pF1KE1 VGKKTLFCNASKEWDNTTTECRLGHC--PDPVLVNGEFSSSGPVNVSDKITFMCNDHYIL
::... : :. :... :.: ::: :::. :::..:..: . : ....:: . :
XP_011 VGSHVRECLANGLWSGSETRCLAGHCGSPDPI-VNGHISGDG-FSYRDTVVYQCNPGFRL
1690 1700 1710 1720 1730 1740
120 130 140 150 160 170
pF1KE1 KGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVG
:.. ::.:: :. :.: : ::::.::. .:..:.:...... :. : : :
XP_011 VGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQG
1750 1760 1770 1780 1790 1800
180 190 200 210 220 230
pF1KE1 VQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMT
:.. :: .:.::: ::.:.... . :.:. :. :. :..: :. :
XP_011 VSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQ--NFPESFEYGMSILYHCKKG
1810 1820 1830 1840 1850 1860
240 250
pF1KE1 MEELKYSLELKKAELKAKLL
XP_011 FYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSES
1870 1880 1890 1900 1910 1920
>--
initn: 380 init1: 193 opt: 292 Z-score: 305.5 bits: 67.4 E(85289): 2.8e-10
Smith-Waterman score: 292; 27.0% identity (55.7% similar) in 185 aa overlap (23-201:2128-2310)
10 20 30 40 50
pF1KE1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKG
::. :::.:. ... . .: :. :
XP_011 YVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDG
2100 2110 2120 2130 2140 2150
60 70 80 90 100 110
pF1KE1 YHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITFMCNDHY
:.: . : :.. : . .: : :: . ..:..:... . .... :.:.. .
XP_011 YQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKS-FTYKSEVFFQCKSPF
2160 2170 2180 2190 2200 2210
120 130 140 150 160
pF1KE1 ILKGSNRSQCLEDHTWAPPFPIC---KSRDCDPPGNPVHGYFEGN-NFTLGSTISYYCED
:: ::.: : : ::. : : : ::.: : ... .. .:::. . :.
XP_011 ILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRK
2220 2230 2240 2250 2260 2270
170 180 190 200 210 220
pF1KE1 RYYLVGVQEQQCVDG-EWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQL
:.. : . :. . ::. : . . .::
XP_011 GYHIQGSTTRTCLANLTWSGIQTEC-IPHACRQPETPAHADVRAIDLPTFGYTLVYTCHP
2280 2290 2300 2310 2320 2330
230 240 250
pF1KE1 KESGMTMEELKYSLELKKAELKAKLL
XP_011 GFFLAGGSEHRTCKADMKWTGKSPVCKSKGVREVNETVTKTPVPSDVFFVNSLWKGYYEY
2340 2350 2360 2370 2380 2390
>--
initn: 420 init1: 171 opt: 271 Z-score: 283.3 bits: 63.3 E(85289): 4.9e-09
Smith-Waterman score: 271; 28.3% identity (55.3% similar) in 152 aa overlap (47-194:1975-2126)
20 30 40 50 60 70
pF1KE1 ASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC
. : :..: :. : . :.. :
XP_011 GNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVC
1950 1960 1970 1980 1990 2000
80 90 100 110 120 130
pF1KE1 RLGHCPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICK
. : .: . .:: . :: . :... . : . : .: .: . ::. : :
XP_011 EAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCT
2010 2020 2030 2040 2050 2060
140 150 160 170 180 190
pF1KE1 SRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQ--QCV-DGEWSSALPVCK
.: ::. ..: :..::...:.:: :. : . .: .:. ::.:. . ::::
XP_011 IISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCK
2070 2080 2090 2100 2110 2120
200 210 220 230 240 250
pF1KE1 LIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLELKKAELKAKLL
.
XP_011 AVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV
2130 2140 2150 2160 2170 2180
>--
initn: 243 init1: 128 opt: 206 Z-score: 214.5 bits: 50.6 E(85289): 3.3e-05
Smith-Waterman score: 222; 29.3% identity (52.0% similar) in 123 aa overlap (47-161:1856-1973)
20 30 40 50 60 70
pF1KE1 ASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC
: : ::..:.:...: : :. :: . .:
XP_011 NCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKC
1830 1840 1850 1860 1870 1880
80 90 100 110 120 130
pF1KE1 RLGHCPDP-----VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPF
: : ....::. . : : . . : : :.. : :: :. .
XP_011 LAISCGHPGVPANAVLTGELFTYGAV-----VHYSCRGSESLIGNDTRVCQEDSHWSGAL
1890 1900 1910 1920 1930 1940
140 150 160 170 180
pF1KE1 PICKSRD---CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSAL
: : . . : ::.:.:: :..: : .
XP_011 PHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGL
1950 1960 1970 1980 1990 2000
190 200 210 220 230 240
pF1KE1 PVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLELKKAELK
XP_011 QPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTA
2010 2020 2030 2040 2050 2060
>>XP_016869220 (OMIM: 608397) PREDICTED: CUB and sushi d (3327 aa)
initn: 417 init1: 351 opt: 455 Z-score: 476.5 bits: 99.4 E(85289): 8.4e-20
Smith-Waterman score: 455; 35.3% identity (64.7% similar) in 204 aa overlap (26-226:2627-2824)
10 20 30 40 50
pF1KE1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHL
.:: :.: . : : . ..: :: :
XP_016 WRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLT-VYGAT-AIFTCNTGYTL
2600 2610 2620 2630 2640 2650
60 70 80 90 100 110
pF1KE1 VGKKTLFCNASKEWDNTTTECRLGHC--PDPVLVNGEFSSSGPVNVSDKITFMCNDHYIL
::... : :. :... :.: ::: :::. :::..:..: . : ....:: . :
XP_016 VGSHVRECLANGLWSGSETRCLAGHCGSPDPI-VNGHISGDG-FSYRDTVVYQCNPGFRL
2660 2670 2680 2690 2700 2710
120 130 140 150 160 170
pF1KE1 KGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVG
:.. ::.:: :. :.: : ::::.::. .:..:.:...... :. : : :
XP_016 VGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQG
2720 2730 2740 2750 2760 2770
180 190 200 210 220 230
pF1KE1 VQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMT
:.. :: .:.::: ::.:.... . :.:. :. :. :..: :. :
XP_016 VSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQ--NFPESFEYGMSILYHCKKG
2780 2790 2800 2810 2820 2830
240 250
pF1KE1 MEELKYSLELKKAELKAKLL
XP_016 FYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSES
2840 2850 2860 2870 2880 2890
>--
initn: 380 init1: 193 opt: 293 Z-score: 305.1 bits: 67.7 E(85289): 2.9e-10
Smith-Waterman score: 293; 27.7% identity (55.9% similar) in 177 aa overlap (23-193:3097-3272)
10 20 30 40 50
pF1KE1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKG
::. :::.:. ... . .: :. :
XP_016 YVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDG
3070 3080 3090 3100 3110 3120
60 70 80 90 100 110
pF1KE1 YHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITFMCNDHY
:.: . : :.. : . .: : :: . ..:..:... . .... :.:.. .
XP_016 YQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKS-FTYKSEVFFQCKSPF
3130 3140 3150 3160 3170 3180
120 130 140 150 160
pF1KE1 ILKGSNRSQCLEDHTWAPPFPIC---KSRDCDPPGNPVHGYFEGN-NFTLGSTISYYCED
:: ::.: : : ::. : : : ::.: : ... .. .:::. . :.
XP_016 ILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRK
3190 3200 3210 3220 3230 3240
170 180 190 200 210 220
pF1KE1 RYYLVGVQEQQCVDG-EWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQL
:.. : . :. . ::. : :
XP_016 GYHIQGSTTRTCLANLTWSGIQTECILWFPRTGSITIGWTLGCEGCSQAPSLTLNQSLWR
3250 3260 3270 3280 3290 3300
>--
initn: 420 init1: 171 opt: 271 Z-score: 281.9 bits: 63.4 E(85289): 5.8e-09
Smith-Waterman score: 271; 28.3% identity (55.3% similar) in 152 aa overlap (47-194:2944-3095)
20 30 40 50 60 70
pF1KE1 ASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC
. : :..: :. : . :.. :
XP_016 GNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVC
2920 2930 2940 2950 2960 2970
80 90 100 110 120 130
pF1KE1 RLGHCPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICK
. : .: . .:: . :: . :... . : . : .: .: . ::. : :
XP_016 EAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCT
2980 2990 3000 3010 3020 3030
140 150 160 170 180 190
pF1KE1 SRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQ--QCV-DGEWSSALPVCK
.: ::. ..: :..::...:.:: :. : . .: .:. ::.:. . ::::
XP_016 IISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCK
3040 3050 3060 3070 3080 3090
200 210 220 230 240 250
pF1KE1 LIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLELKKAELKAKLL
.
XP_016 AVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV
3100 3110 3120 3130 3140 3150
>--
initn: 243 init1: 128 opt: 206 Z-score: 213.1 bits: 50.7 E(85289): 3.9e-05
Smith-Waterman score: 222; 29.3% identity (52.0% similar) in 123 aa overlap (47-161:2825-2942)
20 30 40 50 60 70
pF1KE1 ASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC
: : ::..:.:...: : :. :: . .:
XP_016 NCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKC
2800 2810 2820 2830 2840 2850
80 90 100 110 120 130
pF1KE1 RLGHCPDP-----VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPF
: : ....::. . : : . . : : :.. : :: :. .
XP_016 LAISCGHPGVPANAVLTGELFTYGAV-----VHYSCRGSESLIGNDTRVCQEDSHWSGAL
2860 2870 2880 2890 2900
140 150 160 170 180
pF1KE1 PICKSRD---CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSAL
: : . . : ::.:.:: :..: : .
XP_016 PHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGL
2910 2920 2930 2940 2950 2960
190 200 210 220 230 240
pF1KE1 PVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLELKKAELK
XP_016 QPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTA
2970 2980 2990 3000 3010 3020
252 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:40:22 2016 done: Sun Nov 6 18:40:23 2016
Total Scan time: 6.750 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]