FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1744, 245 aa
  1>>>pF1KE1744 245 - 245 aa - 245 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.5131+/-0.000316; mu= 18.7803+/- 0.020
 mean_var=54.4005+/-11.157, 0's: 0 Z-trim(115.0): 11  B-trim: 221 in 1/54
 Lambda= 0.173889
 statistics sampled from 25212 (25220) to 25212 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.688), E-opt: 0.2 (0.296), width:  16
 Scan time:  6.150

The best scores are:                                      opt bits E(85289)
NP_000358 (OMIM: 187680,610460) thiopurine S-methy ( 245) 1692 432.0 4.6e-121
XP_016866730 (OMIM: 187680,610460) PREDICTED: thio ( 245) 1692 432.0 4.6e-121
XP_011513141 (OMIM: 187680,610460) PREDICTED: thio ( 230) 1328 340.7 1.4e-93


>>NP_000358 (OMIM: 187680,610460) thiopurine S-methyltra  (245 aa)
 initn: 1692 init1: 1692 opt: 1692  Z-score: 2294.4  bits: 432.0 E(85289): 4.6e-121
Smith-Waterman score: 1692; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245)

               10        20        30        40        50        60
pF1KE1 MDGTRTSLDIEEYSDTEVQKNQVLTLEEWQDKWVNGKTAFHQEQGHQLLKKHLDTFLKGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MDGTRTSLDIEEYSDTEVQKNQVLTLEEWQDKWVNGKTAFHQEQGHQLLKKHLDTFLKGK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 SGLRVFFPLCGKAVEMKWFADRGHSVVGVEISELGIQEFFTEQNLSYSEEPITEIPGTKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SGLRVFFPLCGKAVEMKWFADRGHSVVGVEISELGIQEFFTEQNLSYSEEPITEIPGTKV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 FKSSSGNISLYCCSIFDLPRTNIGKFDMIWDRGALVAINPGDRKCYADTMFSLLGKKFQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FKSSSGNISLYCCSIFDLPRTNIGKFDMIWDRGALVAINPGDRKCYADTMFSLLGKKFQY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 LLCVLSYDPTKHPGPPFYVPHAEIERLFGKICNIRCLEKVDAFEERHKSWGIDCLFEKLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LLCVLSYDPTKHPGPPFYVPHAEIERLFGKICNIRCLEKVDAFEERHKSWGIDCLFEKLY
              190       200       210       220       230       240

            
pF1KE1 LLTEK
       :::::
NP_000 LLTEK
            

>>XP_016866730 (OMIM: 187680,610460) PREDICTED: thiopuri  (245 aa)
 initn: 1692 init1: 1692 opt: 1692  Z-score: 2294.4  bits: 432.0 E(85289): 4.6e-121
Smith-Waterman score: 1692; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245)

               10        20        30        40        50        60
pF1KE1 MDGTRTSLDIEEYSDTEVQKNQVLTLEEWQDKWVNGKTAFHQEQGHQLLKKHLDTFLKGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDGTRTSLDIEEYSDTEVQKNQVLTLEEWQDKWVNGKTAFHQEQGHQLLKKHLDTFLKGK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 SGLRVFFPLCGKAVEMKWFADRGHSVVGVEISELGIQEFFTEQNLSYSEEPITEIPGTKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGLRVFFPLCGKAVEMKWFADRGHSVVGVEISELGIQEFFTEQNLSYSEEPITEIPGTKV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 FKSSSGNISLYCCSIFDLPRTNIGKFDMIWDRGALVAINPGDRKCYADTMFSLLGKKFQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKSSSGNISLYCCSIFDLPRTNIGKFDMIWDRGALVAINPGDRKCYADTMFSLLGKKFQY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 LLCVLSYDPTKHPGPPFYVPHAEIERLFGKICNIRCLEKVDAFEERHKSWGIDCLFEKLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLCVLSYDPTKHPGPPFYVPHAEIERLFGKICNIRCLEKVDAFEERHKSWGIDCLFEKLY
              190       200       210       220       230       240

            
pF1KE1 LLTEK
       :::::
XP_016 LLTEK
            

>>XP_011513141 (OMIM: 187680,610460) PREDICTED: thiopuri  (230 aa)
 initn: 1328 init1: 1328 opt: 1328  Z-score: 1801.3  bits: 340.7 E(85289): 1.4e-93
Smith-Waterman score: 1541; 93.9% identity (93.9% similar) in 245 aa overlap (1-245:1-230)

               10        20        30        40        50        60
pF1KE1 MDGTRTSLDIEEYSDTEVQKNQVLTLEEWQDKWVNGKTAFHQEQGHQLLKKHLDTFLKGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDGTRTSLDIEEYSDTEVQKNQVLTLEEWQDKWVNGKTAFHQEQGHQLLKKHLDTFLKGK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 SGLRVFFPLCGKAVEMKWFADRGHSVVGVEISELGIQEFFTEQNLSYSEEPITEIPGTKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLRVFFPLCGKAVEMKWFADRGHSVVGVEISELGIQEFFTEQNLSYSEEPITEIPGTKV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 FKSSSGNISLYCCSIFDLPRTNIGKFDMIWDRGALVAINPGDRKCYADTMFSLLGKKFQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FKSSSGNISLYCCSIFDLPRTNIGKFDMIWDRGALVAINPGDRKCYADTMFSLLGKKFQY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 LLCVLSYDPTKHPGPPFYVPHAEIERLFGKICNIRCLEKVDAFEERHKSWGIDCLFEKLY
       ::::::::::::::               :::::::::::::::::::::::::::::::
XP_011 LLCVLSYDPTKHPG---------------KICNIRCLEKVDAFEERHKSWGIDCLFEKLY
              190                      200       210       220     

            
pF1KE1 LLTEK
       :::::
XP_011 LLTEK
         230




245 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 16:58:58 2016 done: Sun Nov  6 16:58:58 2016
 Total Scan time:  6.150 Total Display time: -0.040

Function used was FASTA [36.3.4 Apr, 2011]