FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1713, 216 aa
  1>>>pF1KE1713 216 - 216 aa - 216 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5767+/-0.000715; mu= 12.6157+/- 0.043
 mean_var=67.4983+/-13.371, 0's: 0 Z-trim(109.7): 37  B-trim: 0 in 0/51
 Lambda= 0.156109
 statistics sampled from 11025 (11062) to 11025 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.34), width:  16
 Scan time:  2.240

The best scores are:                                      opt bits E(32554)
CCDS8193.1 FGF19 gene_id:9965|Hs108|chr11          ( 216) 1486 343.0 8.6e-95
CCDS12734.1 FGF21 gene_id:26291|Hs108|chr19        ( 209)  362 89.8 1.3e-18
CCDS8526.1 FGF23 gene_id:8074|Hs108|chr12          ( 251)  252 65.1 4.5e-11


>>CCDS8193.1 FGF19 gene_id:9965|Hs108|chr11               (216 aa)
 initn: 1486 init1: 1486 opt: 1486  Z-score: 1815.3  bits: 343.0 E(32554): 8.6e-95
Smith-Waterman score: 1486; 100.0% identity (100.0% similar) in 216 aa overlap (1-216:1-216)

               10        20        30        40        50        60
pF1KE1 MRSGCVVVHVWILAGLWLAVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MRSGCVVVHVWILAGLWLAVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 RIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 RIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 AFEEEIRPDGYNVYRSEKHRLPVSLSSAKQRQLYKNRGFLPLSHFLPMLPMVPEEPEDLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 AFEEEIRPDGYNVYRSEKHRLPVSLSSAKQRQLYKNRGFLPLSHFLPMLPMVPEEPEDLR
              130       140       150       160       170       180

              190       200       210      
pF1KE1 GHLESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK
       ::::::::::::::::::::::::::::::::::::
CCDS81 GHLESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK
              190       200       210      

>>CCDS12734.1 FGF21 gene_id:26291|Hs108|chr19             (209 aa)
 initn: 297 init1: 259 opt: 362  Z-score: 447.4  bits: 89.8 E(32554): 1.3e-18
Smith-Waterman score: 362; 38.7% identity (61.8% similar) in 212 aa overlap (10-214:13-207)

                  10           20        30        40        50    
pF1KE1    MRSGCVVVHVWI--LAGLWL-AVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHG
                   .:.  :::: : :  ..:.   :..: ...: :. .: :.:::.  . 
CCDS12 MDSDETGFEHSGLWVSVLAGLLLGACQAHPI--PDSSPLLQFG-GQ-VRQRYLYTDDAQQ
               10        20        30          40          50      

           60        70        80        90       100       110    
pF1KE1 LSSCFLRIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQ
        .   :.:: ::.:  :  :: .:::..::.   .. : ::.. :.::.  :: . : :.
CCDS12 -TEAHLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLH
          60        70        80        90       100       110     

          120       130       140       150           160       170
pF1KE1 YSEEDCAFEEEIRPDGYNVYRSEKHRLPVSLSSAKQ-RQLYKNRG---FLPLSHFLPMLP
       .. : :.:.: .  ::::::.:: : ::. : . :. ..    ::   ::::   ::  :
CCDS12 FDPEACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPG-LP--P
         120       130       140       150       160        170    

              180       190       200       210      
pF1KE1 MVPEEPEDLRGHLESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK
        .:: :    : :      .: .. : ::...: :    ::::.  
CCDS12 ALPEPP----GILA----PQPPDVGSSDPLSMV-GPSQGRSPSYAS
                180           190        200         

>>CCDS8526.1 FGF23 gene_id:8074|Hs108|chr12               (251 aa)
 initn: 208 init1: 180 opt: 252  Z-score: 312.3  bits: 65.1 E(32554): 4.5e-11
Smith-Waterman score: 252; 31.4% identity (56.5% similar) in 191 aa overlap (8-192:6-190)

               10        20        30        40        50        60
pF1KE1 MRSGCVVVHVWILAGLWLAVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFL
              ...:. :   .   .   :. .:.: .  .::  :   ::::.  .  .:  :
CCDS85   MLGARLRLWVCALCSVCSMSVLRAYPNASPLLGSSWGGLI---HLYTATAR--NSYHL
                 10        20        30        40             50   

               70        80        90       100       110       120
pF1KE1 RIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDC
       .:. .: :: :  :. .: : :..     :.: :: : :::::   :.. :   .. :.:
CCDS85 QIHKNGHVDGAPHQTIYSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGSHYFDPENC
            60        70        80        90       100       110   

              130       140       150       160          170       
pF1KE1 AFEEEIRPDGYNVYRSEKHRLPVSLSSAKQRQLYKNRGFLPLSHFLPM---LPMVPEEPE
        :...   .::.::.: .... :::. :: : .  . .  : :.::     .:..  .  
CCDS85 RFQHQTLENGYDVYHSPQYHFLVSLGRAK-RAFLPGMNPPPYSQFLSRRNEIPLIHFNTP
           120       130       140        150       160       170  

       180          190       200       210                        
pF1KE1 DLRGHL---ESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK                  
         : :    :.:   .::                                          
CCDS85 IPRRHTRSAEDDSERDPLNVLKPRARMTPAPASCSQELPSAEDNSPMASDPLGVVRGGRV
            180       190       200       210       220       230  




216 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 15:06:56 2016 done: Sun Nov  6 15:06:56 2016
 Total Scan time:  2.240 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]