Result of FASTA (omim) for
pFN21AE1712
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1712, 216 aa
1>>>pF1KE1712 216 - 216 aa - 216 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7755+/-0.000339; mu= 16.9030+/- 0.021
mean_var=66.6969+/-13.188, 0's: 0 Z-trim(114.0): 204 B-trim: 0 in 0/55
Lambda= 0.157044
statistics sampled from 23363 (23577) to 23363 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.276), width: 16
Scan time: 4.560
The best scores are: opt bits E(85289)
NP_031386 (OMIM: 611817) NKG2-D type II integral m ( 216) 1544 358.4 5.2e-99
NP_001107868 (OMIM: 602894) natural killer cells a ( 179) 307 78.0 1.1e-14
NP_002253 (OMIM: 602894) natural killer cells anti ( 179) 307 78.0 1.1e-14
NP_031360 (OMIM: 602894) natural killer cells anti ( 148) 305 77.5 1.3e-14
XP_016874780 (OMIM: 602894) PREDICTED: natural kil ( 179) 305 77.6 1.5e-14
XP_016874778 (OMIM: 602894) PREDICTED: natural kil ( 188) 291 74.4 1.4e-13
XP_016874776 (OMIM: 602894) PREDICTED: natural kil ( 219) 291 74.5 1.5e-13
XP_016874777 (OMIM: 602894) PREDICTED: natural kil ( 189) 288 73.8 2.2e-13
XP_016874775 (OMIM: 602894) PREDICTED: natural kil ( 220) 288 73.8 2.4e-13
XP_016874774 (OMIM: 602894) PREDICTED: natural kil ( 220) 288 73.8 2.4e-13
XP_011518952 (OMIM: 602894) PREDICTED: natural kil ( 220) 288 73.8 2.4e-13
XP_016874885 (OMIM: 606783) PREDICTED: C-type lect ( 173) 285 73.0 3.3e-13
NP_001092901 (OMIM: 606783) C-type lectin domain f ( 196) 285 73.1 3.6e-13
XP_011518987 (OMIM: 606783) PREDICTED: C-type lect ( 196) 285 73.1 3.6e-13
NP_057593 (OMIM: 606783) C-type lectin domain fami ( 229) 285 73.1 4e-13
XP_016874884 (OMIM: 606783) PREDICTED: C-type lect ( 229) 285 73.1 4e-13
XP_005253439 (OMIM: 606783) PREDICTED: C-type lect ( 229) 285 73.1 4e-13
NP_002534 (OMIM: 602601,608446) oxidized low-densi ( 273) 284 73.0 5.4e-13
XP_016874779 (OMIM: 602894) PREDICTED: natural kil ( 185) 280 71.9 7.6e-13
XP_006719130 (OMIM: 602894) PREDICTED: natural kil ( 185) 280 71.9 7.6e-13
XP_011518953 (OMIM: 602894) PREDICTED: natural kil ( 186) 280 71.9 7.6e-13
NP_997228 (OMIM: 612252) C-type lectin domain fami ( 241) 276 71.1 1.7e-12
NP_001138379 (OMIM: 605872) C-type lectin domain f ( 332) 268 69.4 7.7e-12
NP_001138378 (OMIM: 605872) C-type lectin domain f ( 263) 265 68.7 1e-11
XP_005272529 (OMIM: 604672,607948,609423,614371) P ( 266) 264 68.4 1.2e-11
XP_006722677 (OMIM: 605872) PREDICTED: C-type lect ( 343) 265 68.8 1.3e-11
NP_001138376 (OMIM: 605872) C-type lectin domain f ( 348) 265 68.8 1.3e-11
NP_001138381 (OMIM: 605872) C-type lectin domain f ( 353) 265 68.8 1.3e-11
XP_006722675 (OMIM: 605872) PREDICTED: C-type lect ( 371) 265 68.8 1.3e-11
XP_006722676 (OMIM: 605872) PREDICTED: C-type lect ( 371) 265 68.8 1.3e-11
XP_016874174 (OMIM: 604874) PREDICTED: killer cell ( 199) 262 67.9 1.3e-11
XP_016874172 (OMIM: 604874) PREDICTED: killer cell ( 199) 262 67.9 1.3e-11
XP_016874173 (OMIM: 604874) PREDICTED: killer cell ( 199) 262 67.9 1.3e-11
XP_016874171 (OMIM: 604874) PREDICTED: killer cell ( 199) 262 67.9 1.3e-11
NP_001138377 (OMIM: 605872) C-type lectin domain f ( 375) 265 68.8 1.4e-11
NP_001138382 (OMIM: 605872) C-type lectin domain f ( 376) 265 68.8 1.4e-11
XP_006722674 (OMIM: 605872) PREDICTED: C-type lect ( 398) 265 68.8 1.4e-11
NP_055072 (OMIM: 605872) C-type lectin domain fami ( 399) 265 68.8 1.4e-11
NP_001138371 (OMIM: 604672,607948,609423,614371) C ( 243) 261 67.7 1.8e-11
NP_001138365 (OMIM: 604672,607948,609423,614371) C ( 268) 261 67.8 2e-11
NP_001138367 (OMIM: 604672,607948,609423,614371) C ( 312) 261 67.8 2.2e-11
NP_001138366 (OMIM: 604672,607948,609423,614371) C ( 360) 261 67.9 2.5e-11
NP_001138368 (OMIM: 604672,607948,609423,614371) C ( 380) 261 67.9 2.6e-11
NP_066978 (OMIM: 604672,607948,609423,614371) CD20 ( 404) 261 67.9 2.7e-11
NP_005801 (OMIM: 604874) killer cell lectin-like r ( 189) 257 66.7 2.8e-11
NP_001316028 (OMIM: 604874) killer cell lectin-lik ( 195) 257 66.7 2.9e-11
XP_011518988 (OMIM: 606783) PREDICTED: C-type lect ( 189) 254 66.1 4.6e-11
NP_001284678 (OMIM: 606782) C-type lectin domain f ( 188) 251 65.4 7.3e-11
NP_002250 (OMIM: 161555) NKG2-A/NKG2-B type II int ( 233) 252 65.7 7.3e-11
NP_998823 (OMIM: 161555) NKG2-A/NKG2-B type II int ( 233) 252 65.7 7.3e-11
>>NP_031386 (OMIM: 611817) NKG2-D type II integral membr (216 aa)
initn: 1544 init1: 1544 opt: 1544 Z-score: 1898.5 bits: 358.4 E(85289): 5.2e-99
Smith-Waterman score: 1544; 99.5% identity (100.0% similar) in 216 aa overlap (1-216:1-216)
10 20 30 40 50 60
pF1KE1 MGWIRGRRSRHSWEMSEFHNYNLDLKKSDFSTRWQKQRCPVVKSKCRENASPFFFCCFIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 MGWIRGRRSRHSWEMSEFHNYNLDLKKSDFSTRWQKQRCPVVKSKCRENASPFFFCCFIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VAMGIRFIIMVAIWSAVFLNSLFNQEVQIPLTESYCGPCPKNWICYKNNCYQFFDESKNW
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 VAMGIRFIIMVTIWSAVFLNSLFNQEVQIPLTESYCGPCPKNWICYKNNCYQFFDESKNW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YESQASCMSQNASLLKVYSKEDQDLLKLVKSYHWMGLVHIPTNGSWQWEDGSILSPNLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 YESQASCMSQNASLLKVYSKEDQDLLKLVKSYHWMGLVHIPTNGSWQWEDGSILSPNLLT
130 140 150 160 170 180
190 200 210
pF1KE1 IIEMQKGDCALYASSFKGYIENCSTPNTYICMQRTV
::::::::::::::::::::::::::::::::::::
NP_031 IIEMQKGDCALYASSFKGYIENCSTPNTYICMQRTV
190 200 210
>>NP_001107868 (OMIM: 602894) natural killer cells antig (179 aa)
initn: 221 init1: 200 opt: 307 Z-score: 384.9 bits: 78.0 E(85289): 1.1e-14
Smith-Waterman score: 308; 28.4% identity (60.9% similar) in 169 aa overlap (58-216:11-179)
30 40 50 60 70 80
pF1KE1 SDFSTRWQKQRCPVVKSKCRENASPFFFCCFIAVAMGIRFIIMVAIWSAVFLNSLFNQEV
.:. ..:: . ..: . .. ::. . .
NP_001 MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSI
10 20 30 40
90 100 110 120 130
pF1KE1 QIPLT---------ESYCGPCPKNWICYKNNCYQFFDESKNWYESQASCMSQNASLLKVY
. .: .: : : ..:. :. ::: . .:.:.: ::. : ::..:::..
NP_001 EPAFTPGPNIELQKDSDCCSCQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQ
50 60 70 80 90 100
140 150 160 170 180 190
pF1KE1 SKEDQDLLKLVKSYHWMGLVHIPTNGSWQWEDGSILSPNLLTIIE-MQKGDCALYASSFK
. .. :... ....:.:: . . .: ::.:: :: :. .: .. .: : . .
NP_001 NTDELDFMSSSQQFYWIGLSYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGN
110 120 130 140 150 160
200 210
pF1KE1 GYIENCSTPNTYICMQRTV
. :.: : ::: :. .
NP_001 ALDESCEDKNRYICKQQLI
170
>>NP_002253 (OMIM: 602894) natural killer cells antigen (179 aa)
initn: 221 init1: 200 opt: 307 Z-score: 384.9 bits: 78.0 E(85289): 1.1e-14
Smith-Waterman score: 308; 28.4% identity (60.9% similar) in 169 aa overlap (58-216:11-179)
30 40 50 60 70 80
pF1KE1 SDFSTRWQKQRCPVVKSKCRENASPFFFCCFIAVAMGIRFIIMVAIWSAVFLNSLFNQEV
.:. ..:: . ..: . .. ::. . .
NP_002 MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSI
10 20 30 40
90 100 110 120 130
pF1KE1 QIPLT---------ESYCGPCPKNWICYKNNCYQFFDESKNWYESQASCMSQNASLLKVY
. .: .: : : ..:. :. ::: . .:.:.: ::. : ::..:::..
NP_002 EPAFTPGPNIELQKDSDCCSCQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQ
50 60 70 80 90 100
140 150 160 170 180 190
pF1KE1 SKEDQDLLKLVKSYHWMGLVHIPTNGSWQWEDGSILSPNLLTIIE-MQKGDCALYASSFK
. .. :... ....:.:: . . .: ::.:: :: :. .: .. .: : . .
NP_002 NTDELDFMSSSQQFYWIGLSYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGN
110 120 130 140 150 160
200 210
pF1KE1 GYIENCSTPNTYICMQRTV
. :.: : ::: :. .
NP_002 ALDESCEDKNRYICKQQLI
170
>>NP_031360 (OMIM: 602894) natural killer cells antigen (148 aa)
initn: 221 init1: 200 opt: 305 Z-score: 383.6 bits: 77.5 E(85289): 1.3e-14
Smith-Waterman score: 305; 32.8% identity (63.4% similar) in 134 aa overlap (84-216:18-148)
60 70 80 90 100 110
pF1KE1 FFCCFIAVAMGIRFIIMVAIWSAVFLNSLFNQEVQIPLTESYCGPCPKNWICYKNNCYQF
: :.: .: : : ..:. :. ::: .
NP_031 MAAFTKLSIEPAFTPGPNIELQ---KDSDCCSCQEKWVGYRCNCYFI
10 20 30 40
120 130 140 150 160 170
pF1KE1 FDESKNWYESQASCMSQNASLLKVYSKEDQDLLKLVKSYHWMGLVHIPTNGSWQWEDGSI
.:.:.: ::. : ::..:::.. . .. :... ....:.:: . . .: ::.::
NP_031 SSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLSYSEEHTAWLWENGSA
50 60 70 80 90 100
180 190 200 210
pF1KE1 LSPNLLTIIE-MQKGDCALYASSFKGYIENCSTPNTYICMQRTV
:: :. .: .. .: : . .. :.: : ::: :. .
NP_031 LSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI
110 120 130 140
>>XP_016874780 (OMIM: 602894) PREDICTED: natural killer (179 aa)
initn: 221 init1: 200 opt: 305 Z-score: 382.5 bits: 77.6 E(85289): 1.5e-14
Smith-Waterman score: 305; 32.8% identity (63.4% similar) in 134 aa overlap (84-216:49-179)
60 70 80 90 100 110
pF1KE1 FFCCFIAVAMGIRFIIMVAIWSAVFLNSLFNQEVQIPLTESYCGPCPKNWICYKNNCYQF
: :.: .: : : ..:. :. ::: .
XP_016 ICLSLMSTLGILLKNSFTKLSIEPAFTPGPNIELQ---KDSDCCSCQEKWVGYRCNCYFI
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE1 FDESKNWYESQASCMSQNASLLKVYSKEDQDLLKLVKSYHWMGLVHIPTNGSWQWEDGSI
.:.:.: ::. : ::..:::.. . .. :... ....:.:: . . .: ::.::
XP_016 SSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLSYSEEHTAWLWENGSA
80 90 100 110 120 130
180 190 200 210
pF1KE1 LSPNLLTIIE-MQKGDCALYASSFKGYIENCSTPNTYICMQRTV
:: :. .: .. .: : . .. :.: : ::: :. .
XP_016 LSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI
140 150 160 170
>>XP_016874778 (OMIM: 602894) PREDICTED: natural killer (188 aa)
initn: 245 init1: 200 opt: 291 Z-score: 365.0 bits: 74.4 E(85289): 1.4e-13
Smith-Waterman score: 291; 32.8% identity (63.4% similar) in 131 aa overlap (84-213:18-145)
60 70 80 90 100 110
pF1KE1 FFCCFIAVAMGIRFIIMVAIWSAVFLNSLFNQEVQIPLTESYCGPCPKNWICYKNNCYQF
: :.: .: : : ..:. :. ::: .
XP_016 MAAFTKLSIEPAFTPGPNIELQ---KDSDCCSCQEKWVGYRCNCYFI
10 20 30 40
120 130 140 150 160 170
pF1KE1 FDESKNWYESQASCMSQNASLLKVYSKEDQDLLKLVKSYHWMGLVHIPTNGSWQWEDGSI
.:.:.: ::. : ::..:::.. . .. :... ....:.:: . . .: ::.::
XP_016 SSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLSYSEEHTAWLWENGSA
50 60 70 80 90 100
180 190 200 210
pF1KE1 LSPNLLTIIE-MQKGDCALYASSFKGYIENCSTPNTYICMQRTV
:: :. .: .. .: : . .. :.: : :: .:
XP_016 LSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYIFLQGWRSLRKLTVMTEGKANTS
110 120 130 140 150 160
XP_016 LYAWQQKGDVLSKRKNTLLLNHQI
170 180
>>XP_016874776 (OMIM: 602894) PREDICTED: natural killer (219 aa)
initn: 230 init1: 200 opt: 291 Z-score: 364.1 bits: 74.5 E(85289): 1.5e-13
Smith-Waterman score: 291; 32.8% identity (63.4% similar) in 131 aa overlap (84-213:49-176)
60 70 80 90 100 110
pF1KE1 FFCCFIAVAMGIRFIIMVAIWSAVFLNSLFNQEVQIPLTESYCGPCPKNWICYKNNCYQF
: :.: .: : : ..:. :. ::: .
XP_016 ICLSLMSTLGILLKNSFTKLSIEPAFTPGPNIELQ---KDSDCCSCQEKWVGYRCNCYFI
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE1 FDESKNWYESQASCMSQNASLLKVYSKEDQDLLKLVKSYHWMGLVHIPTNGSWQWEDGSI
.:.:.: ::. : ::..:::.. . .. :... ....:.:: . . .: ::.::
XP_016 SSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLSYSEEHTAWLWENGSA
80 90 100 110 120 130
180 190 200 210
pF1KE1 LSPNLLTIIE-MQKGDCALYASSFKGYIENCSTPNTYICMQRTV
:: :. .: .. .: : . .. :.: : :: .:
XP_016 LSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYIFLQGWRSLRKLTVMTEGKANTS
140 150 160 170 180 190
XP_016 LYAWQQKGDVLSKRKNTLLLNHQI
200 210
>>XP_016874777 (OMIM: 602894) PREDICTED: natural killer (189 aa)
initn: 240 init1: 110 opt: 288 Z-score: 361.3 bits: 73.8 E(85289): 2.2e-13
Smith-Waterman score: 288; 33.3% identity (63.6% similar) in 132 aa overlap (84-213:18-146)
60 70 80 90 100 110
pF1KE1 FFCCFIAVAMGIRFIIMVAIWSAVFLNSLFNQEVQIPLTESYCGPCPKNWICYKNNCYQF
: :.: .: : : ..:. :. ::: .
XP_016 MAAFTKLSIEPAFTPGPNIELQ---KDSDCCSCQEKWVGYRCNCYFI
10 20 30 40
120 130 140 150 160 170
pF1KE1 FDESKNWYESQASCMSQNASLLKVYSKED-QDLLKLVKSYHWMGLVHIPTNGSWQWEDGS
.:.:.: ::. : ::..:::.. . .. ::... ....:.:: . . .: ::.::
XP_016 SSEQKTWNESRHLCASQKSSLLQLQNTDELQDFMSSSQQFYWIGLSYSEEHTAWLWENGS
50 60 70 80 90 100
180 190 200 210
pF1KE1 ILSPNLLTIIE-MQKGDCALYASSFKGYIENCSTPNTYICMQRTV
:: :. .: .. .: : . .. :.: : :: .:
XP_016 ALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYIFLQGWRSLRKLTVMTEGKANT
110 120 130 140 150 160
XP_016 SLYAWQQKGDVLSKRKNTLLLNHQI
170 180
>>XP_016874775 (OMIM: 602894) PREDICTED: natural killer (220 aa)
initn: 225 init1: 110 opt: 288 Z-score: 360.4 bits: 73.8 E(85289): 2.4e-13
Smith-Waterman score: 288; 33.3% identity (63.6% similar) in 132 aa overlap (84-213:49-177)
60 70 80 90 100 110
pF1KE1 FFCCFIAVAMGIRFIIMVAIWSAVFLNSLFNQEVQIPLTESYCGPCPKNWICYKNNCYQF
: :.: .: : : ..:. :. ::: .
XP_016 ICLSLMSTLGILLKNSFTKLSIEPAFTPGPNIELQ---KDSDCCSCQEKWVGYRCNCYFI
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE1 FDESKNWYESQASCMSQNASLLKVYSKED-QDLLKLVKSYHWMGLVHIPTNGSWQWEDGS
.:.:.: ::. : ::..:::.. . .. ::... ....:.:: . . .: ::.::
XP_016 SSEQKTWNESRHLCASQKSSLLQLQNTDELQDFMSSSQQFYWIGLSYSEEHTAWLWENGS
80 90 100 110 120 130
180 190 200 210
pF1KE1 ILSPNLLTIIE-MQKGDCALYASSFKGYIENCSTPNTYICMQRTV
:: :. .: .. .: : . .. :.: : :: .:
XP_016 ALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYIFLQGWRSLRKLTVMTEGKANT
140 150 160 170 180 190
XP_016 SLYAWQQKGDVLSKRKNTLLLNHQI
200 210 220
>>XP_016874774 (OMIM: 602894) PREDICTED: natural killer (220 aa)
initn: 225 init1: 110 opt: 288 Z-score: 360.4 bits: 73.8 E(85289): 2.4e-13
Smith-Waterman score: 288; 33.3% identity (63.6% similar) in 132 aa overlap (84-213:49-177)
60 70 80 90 100 110
pF1KE1 FFCCFIAVAMGIRFIIMVAIWSAVFLNSLFNQEVQIPLTESYCGPCPKNWICYKNNCYQF
: :.: .: : : ..:. :. ::: .
XP_016 ICLSLMSTLGILLKNSFTKLSIEPAFTPGPNIELQ---KDSDCCSCQEKWVGYRCNCYFI
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE1 FDESKNWYESQASCMSQNASLLKVYSKED-QDLLKLVKSYHWMGLVHIPTNGSWQWEDGS
.:.:.: ::. : ::..:::.. . .. ::... ....:.:: . . .: ::.::
XP_016 SSEQKTWNESRHLCASQKSSLLQLQNTDELQDFMSSSQQFYWIGLSYSEEHTAWLWENGS
80 90 100 110 120 130
180 190 200 210
pF1KE1 ILSPNLLTIIE-MQKGDCALYASSFKGYIENCSTPNTYICMQRTV
:: :. .: .. .: : . .. :.: : :: .:
XP_016 ALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYIFLQGWRSLRKLTVMTEGKANT
140 150 160 170 180 190
XP_016 SLYAWQQKGDVLSKRKNTLLLNHQI
200 210 220
216 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:56:56 2016 done: Sun Nov 6 14:56:57 2016
Total Scan time: 4.560 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]