FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1707, 207 aa
  1>>>pF1KE1707 207 - 207 aa - 207 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.9315+/-0.000468; mu= 2.3031+/- 0.029
 mean_var=175.8777+/-34.305, 0's: 0 Z-trim(114.5): 32  B-trim: 290 in 1/53
 Lambda= 0.096709
 statistics sampled from 24394 (24415) to 24394 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.286), width:  16
 Scan time:  6.320

The best scores are:                                      opt bits E(85289)
NP_079349 (OMIM: 611656) suppressor of IKBKE 1 iso ( 207) 1305 193.9 1.6e-49
NP_001095866 (OMIM: 611656) suppressor of IKBKE 1  ( 211) 1287 191.4 9.2e-49
NP_001165358 (OMIM: 608858) FGFR1 oncogene partner ( 215)  667 104.9   1e-22
NP_001165359 (OMIM: 608858) FGFR1 oncogene partner ( 172)  454 75.1 7.6e-14
NP_056448 (OMIM: 608858) FGFR1 oncogene partner 2  ( 253)  454 75.2   1e-13


>>NP_079349 (OMIM: 611656) suppressor of IKBKE 1 isoform  (207 aa)
 initn: 1305 init1: 1305 opt: 1305  Z-score: 1010.1  bits: 193.9 E(85289): 1.6e-49
Smith-Waterman score: 1305; 100.0% identity (100.0% similar) in 207 aa overlap (1-207:1-207)

               10        20        30        40        50        60
pF1KE1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 AVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 AVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKEL
              130       140       150       160       170       180

              190       200       
pF1KE1 RELLSISSESLQARKENSMDTASQAIK
       :::::::::::::::::::::::::::
NP_079 RELLSISSESLQARKENSMDTASQAIK
              190       200       

>>NP_001095866 (OMIM: 611656) suppressor of IKBKE 1 isof  (211 aa)
 initn: 978 init1: 978 opt: 1287  Z-score: 996.5  bits: 191.4 E(85289): 9.2e-49
Smith-Waterman score: 1287; 98.1% identity (98.1% similar) in 211 aa overlap (1-207:1-211)

               10        20        30        40        50          
pF1KE1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQ----YQE
       :::::::::::::::::::::::::::::::::::::::::::::::::::::    :::
NP_001 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KE1 DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KE1 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE
              130       140       150       160       170       180

        180       190       200       
pF1KE1 NKELRELLSISSESLQARKENSMDTASQAIK
       :::::::::::::::::::::::::::::::
NP_001 NKELRELLSISSESLQARKENSMDTASQAIK
              190       200       210 

>>NP_001165358 (OMIM: 608858) FGFR1 oncogene partner 2 i  (215 aa)
 initn: 727 init1: 441 opt: 667  Z-score: 528.8  bits: 104.9 E(85289): 1e-22
Smith-Waterman score: 667; 51.4% identity (81.2% similar) in 208 aa overlap (1-203:1-200)

               10        20        30        40        50        60
pF1KE1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASD
       ::::::: :.:::.:.::::.:: :::::..:..::..:: ::.        ::::. ..
NP_001 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMK--------QYQEEIQE
               10        20        30        40                50  

               70            80        90       100       110      
pF1KE1 MKDMSKYKPHILL----SQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM
       ........:.  :    .::: :::.:::::.::  ::::::.::::::::::.::..:.
NP_001 LNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLL
             60        70        80        90       100       110  

        120       130       140       150       160       170      
pF1KE1 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE
       .:.:  :   ..: ...:: :.....:.: ::. :::::...:..: :: ::.. ::: :
NP_001 MASKKDDPGIIMKLKEQHSKELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQE
            120       130       140       150       160       170  

        180       190        200                  
pF1KE1 NKELRELLSISSES-LQARKENSMDTASQAIK           
       :: :::.:.:. :: :. ::... ...:               
NP_001 NKGLREILQITRESFLNLRKDDASESTSLSALVTNSDLSLRKS
            180       190       200       210     

>>NP_001165359 (OMIM: 608858) FGFR1 oncogene partner 2 i  (172 aa)
 initn: 474 init1: 243 opt: 454  Z-score: 369.6  bits: 75.1 E(85289): 7.6e-14
Smith-Waterman score: 454; 53.2% identity (80.6% similar) in 139 aa overlap (1-135:1-131)

               10        20        30        40        50        60
pF1KE1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASD
       ::::::: :.:::.:.::::.:: :::::..:..::..:: ::.        ::::. ..
NP_001 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMK--------QYQEEIQE
               10        20        30        40                50  

               70            80        90       100       110      
pF1KE1 MKDMSKYKPHILL----SQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM
       ........:.  :    .::: :::.:::::.::  ::::::.::::::::::.::..:.
NP_001 LNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLL
             60        70        80        90       100       110  

        120       130       140       150       160       170      
pF1KE1 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE
       .:.:  :   ..: ...::                                         
NP_001 MASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNVH
            120       130       140       150       160       170  

>>NP_056448 (OMIM: 608858) FGFR1 oncogene partner 2 isof  (253 aa)
 initn: 630 init1: 243 opt: 454  Z-score: 367.3  bits: 75.2 E(85289): 1e-13
Smith-Waterman score: 574; 44.0% identity (68.5% similar) in 241 aa overlap (1-198:1-233)

               10        20        30        40        50        60
pF1KE1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASD
       ::::::: :.:::.:.::::.:: :::::..:..::..:: ::.        ::::. ..
NP_056 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMK--------QYQEEIQE
               10        20        30        40                50  

               70            80        90       100       110      
pF1KE1 MKDMSKYKPHILL----SQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM
       ........:.  :    .::: :::.:::::.::  ::::::.::::::::::.::..:.
NP_056 LNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLL
             60        70        80        90       100       110  

        120       130                                              
pF1KE1 VAKKAVDAEPVLKAHQSHSA--------------------------------------EI
       .:.:  :   ..: ...::                                       :.
NP_056 MASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNEL
            120       130       140       150       160       170  

      140       150       160       170       180       190        
pF1KE1 ESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSES-LQARKEN
       ....:.: ::. :::::...:..: :: ::.. ::: ::: :::.:.:. :: :. ::..
NP_056 QAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDD
            180       190       200       210       220       230  

       200                  
pF1KE1 SMDTASQAIK           
       .                    
NP_056 ASESTSLSALVTNSDLSLRKS
            240       250   




207 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 18:59:33 2016 done: Sun Nov  6 18:59:34 2016
 Total Scan time:  6.320 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]